Debt Ceiling Negotiations Come Down to the Wire

PAGE 5 PAGE 6 INSERT Report: U.S. Lagging in Stem Cell Lawsuit The Role of the CDC in University R&D Dismissed Global Health R&D

JULY-AUGUST 2011 ReTHEsearch ADVOCATE BRINGING RESEARCH CLOSER TO HOME

Debt Ceiling Negotiations Come Down to the Wire At the time of this writing, debt ceiling tus to cut funding for health research these caps would limit the amount by negotiations between the White House and all discretionary programs has which agency budgets are able to grow. and congressional leadership have never been greater and it is up to you The National Institutes of Health stalled. Recent proposals for raising to turn the tide. budget, for example, is currently about the debt ceiling have included manda- If an agreement is reached, it could $31 billion for this fiscal year. A long- tory long-term spending cuts and result in deep cuts in funding for term spending cap would hamstring spending caps. Everyone in the health health research and long-term restric- funding for health research at NIH and research community needs to step up tions on any potential future increases other agencies. their advocacy efforts now. The impe- in discretionary spending. Ultimately, Continued on page 4

One Mind Forum Lays Out Plan the anniversary of tors and create partnerships toward the for Neuroscience Research former President goal of a greater understanding of brain John F. Kennedy’s disorders. The group hopes to raise an The One Mind for Research Forum, 1961 challenge to send a man to the additional $1.5 billion for brain held in Boston and featuring world- moon within a decade. Vice President research for each of the next 10 years renowned experts from academia, Joe Biden joined many current and for- while also reducing the cost of brain dis- government and industry, detailed a mer Members of Congress to speak at ease care by at least 10%. 10-year plan for neuro- the event; National Institutes of Research!America and several of its science research that Health Director Francis Collins, MD, members and partners—the American could bring new thera- PhD, and Research!America board College of Neuropsychopharmacology, pies and cures for neuro- member Mark McClellan, MD, PhD, the Council for American Medical logical and psychiatric also spoke. Research!America President Innovation, the Critical Path Institute, diseases. and CEO Mary Woolley presented clos- Johnson & Johnson and the Society The forum, organized The ing remarks for the event. for Neuroscience among them—are Honorable by The Honorable Patrick Patrick One Mind’s decade-long plan aims to partner organizations of One Mind Kennedy, coincided with Kennedy unify brain researchers from across sec- for Research.

AMERICA Many Believe Increased Funding for SPEAKS Federal Agencies is Important The following federal agencies play a role in improving the health of Centers for Disease Control and Prevention 46% 37% 8% 4% 5% Americans through research and National Institutes of Health 34% 39% 14% 5% 8% development. How important is it to increase funding for… Food and Drug Administration 34% 39% 17% 5% 5%

SOURCE: YOUR CONGRESS–YOUR HEALTH SURVEY, MARCH 2011, CHARLTON RESEARCH Agency for Healthcare Research and Quality 27% 40% 17% 6% 10 % COMPANY FOR RESEARCH!AMERICA Very important Somewhat important Not too important Not at all important Don’t know Texas Biomedical New ON THE Members Research Institute TAKE Texas Biomedical Research Institute was founded in 1941 by Thomas Slick, Jr. Web Action It was the first institution of its kind in Texas and the harbinger of extraordinary www.researchamerica.org growth in San Antonio’s biomedical sector, which today employs one of every The American Society of Clinical six people in the city. The Institute has a staff of 385 people, including 75 Oncology launched Cancerprogress.net, doctoral-level scientists. Texas Biomed hosts one of eight National Primate an interactive website outlining 40 years Research Centers, a biosafety level-4 laboratory and the world’s largest com- of research progress. puter cluster devoted to human genetic analysis. Kenneth P. CFIDS Association of America Trevett, JD Located on 200 acres animal models for human disease; launched Research1st.com, a website for near downtown San Antonio, the Texas undertaking research in AIDS, hepatitis current information about research being conducted on chronic fatigue syndrome. Biomedical Research Institute, formerly B and C, and, emerging infections; and the Southwest Foundation for pursuing genetic studies of cardiovascu- All PDF versions of books published by Biomedical Research, is on a mission to lar disease, diabetes, mental illnesses, the National Academies are now available for free download at www.nap.edu. build upon its strengths and enhance arthritis and cancer. its research environment. In addition to And for Trevett, Texas Biomed’s The International Aging Research a new name, Texas Biomed is planning membership with Research!America is Portfolio launched FundingTrends.org, a search engine of millions of biomedical 93,000 square feet of new research and an important way to help ensure that research projects and funding. support space, the initiation of a regen- elected officials understand the value erative medicine program and the of research. hiring of 10 additional faculty. “Research!America is invaluable to an And that’s on top of all that Texas organization like ours because it sends Biomed already has—so much so that continuous and informative messages President and CEO Kenneth P. Trevett, about the importance of basic, transla- THE JD, can’t pick a favorite aspect of the tional and clinical research to decision facility. makers,” he said. “The polling conduct- “The combination of high-quality ed by Research!America demonstrating eADVOCATEsearch R science and a unique combination of continuing and strong public support resources makes us a very impactful for the research enterprise is a powerful 1101 King Street, Suite 520 place,” Trevett said. tool that reflects national, and biparti- Alexandria, VA 22314-2960 Texas Biomed is developing new san, priorities.” www.researchamerica.org 703-739-2577 / 800-366-CURE [email protected] Research!America Adds Value Editor: Brian Hunsicker FOR OUR MEMBERS Research!America stands on a reputation of innovative advocacy that generates About Research!America results serving our mission and the interests of our members: Research!America is the nation’s largest 501(c)(3) public education • Global health R&D pays off in lives saved and economies strengthened. Our and advocacy alliance working to global health programs link the two, making the case that global health R&D make research to improve health a higher national priority. Founded in benefits communities abroad with better health and communities at home with a 1989, Research!America is supported better economic climate. by member organizations that • Research!America keeps its finger on the pulses of Congress and the public, together represent the voices of more than 125 million Americans. informing our membership of how it can effectively communicate with local Our public opinion polls, advocacy elected leadership. programs and publications reach the • Our recent media tour of the Centers for Disease Control and Prevention’s head- public and decision makers to help advance medical, health and quarters in Atlanta gave leading journalists an insider’s view of the prevention scientific research. and disease surveillance efforts that the CDC undertakes. • Research isn’t important only for America, but for each of its 50 states. In recent programs, Research!America has highlighted the research being per- formed in Illinois, New Jersey, Ohio and Maryland. Additional state-specific programs are planned.

2 research! america Media President’s MATTERS MESSAGE

Spotlight on Research Partners Forums Not so many years ago, Research!America and Northeast Ohio Medical University held a forum on summertime was greatly research and Ohio’s economy that received coverage in the Akron Beacon Journal, feared as a time of twice in the Record Courier (Ravenna, OH), and the news service Akron News Now. heightened susceptibili- Research!America’s forum on science communication with the University of ty to polio; children Maryland and Pfizer Inc. was featured in Nature’s blog, From the Lab Bench. were routinely denied entry to public swimming pools and Research!America’s Leadership Interviewed kept away from summer activities at Research!America’s chair, former Congressman John Edward Porter, talked about fairs and carnivals. Medical research his work in Congress that led to the doubling of the NIH budget in the journal changed all that forever with the intro- Oncology Times. He warned against partisan politics that stall research funding duction of the polio vaccine. This sum- decisions. He was also quoted in Nature-affiliated EMBO reports: “It’s time for mer, a different but equally compelling both parties to stand up for the country and find solutions to our problems. The fear is stalking us—the very real possi- only way to do that is to invest where we lead the world and that’s in science.” bility of budget cuts to research severe Research!America’s Mary Woolley discussed cognitive biases that can influence enough to shutter labs, put researchers scientists’ research decisions with The Scientist. She said the structure of the peer out of work and set progress back by review process is designed to minimize such biases. She commented on the current years, if not decades. Patients—and political landscape for research for Bloomberg Government and warned that the their family members who care for U.S. risks losing ground in global competitiveness if it scales back its investment in them—would just have to wait. research. She also talked about the importance of sustaining National Institutes It is apparent that the voices of of Health funding in a Nature Medicine article. research leaders, evidence of economic Research!America Board Members in the News impact and widespread public support are not enough to dissuade those in Victor Dzau, MD, chancellor for health affairs at Duke University Congress who are determined to slash and a Research!America board member, was part of a Bloomberg the budgets of agencies that have the TV panel moderated by broadcast journalist Charlie Rose. Dzau word “government” appended. What and co-panelists Craig Barrett, PhD, former chair and CEO of is needed now is increased, vocal, Intel; Sir Martin Sorrell, CEO of the WPP Group; and William persistent advocacy by large numbers of Overholt, PhD, senior research fellow at the Harvard Kennedy people—advocacy capable of compet- Victor Dzau, School of Government, discussed innovation and research. Rose ing with other interests clamoring for MD received a 2011 Research!America Advocacy Award. attention this summer. Evan Jones, managing member of jVen Capital and also a For the first time in Research!America board member, was profiled in The Washington Research!America’s 22-year history, we Post, where he recounted his career in the medical research field. He are asking all those whom we reach— said his two mentors were his grandfather, who founded the company members and everyone each member that later became Jones New York, and his stepfather Jack reaches—to either personally partici- Whitehead, founder of the Whitehead Institute for Biomedical Evan Jones pate in advocacy for research or send a Research and co-founder of Research!America. financial contribution to us for use in Global Health Research Update ramping up an aggressive advocacy Rep. Albio Sires (D-NJ) authored a guest post in The Hill’s Congress Blog about campaign in key parts of the country in the 21st Century Global Health Technology Act. He cited Research!America data the weeks ahead. If you can do both— on the economic impact of global health research in New Jersey to demonstrate participate and send a contribution— the importance of supporting this bill. so much the better! Let us hear from Michael Cassidy, president of the Georgia Research Alliance, wrote an editori- you today; contact Ellie Dehoney, our al in the Atlanta Journal-Constitution about the importance of investing in vice president for policy and programs, research and innovation. “As we grapple with the structural challenges to our at [email protected]. national and state budgets,” he wrote, “a new economic paradigm compelled by innovation and technology could help us escape the budget trap.”

The research advocate 3 Board of Policy DIRECTORS UPDATE O FFICERS The Honorable John Edward Porter, chair Martha N. Hill, PhD, RN, vice chair Mary Woolley, president and CEO Debt Ceiling Negotiations Administration. On June 16, the Georges C. Benjamin, MD, secretary Mary J.C. Hendrix, PhD, treasurer Continued from page 1 House voted on and passed the bill that B OARD M EMBERS Tenley E. Albright, MD cuts FDA funding by $285 million from Nancy Brown While the details of the budget deal FY11 levels. The Honorable Michael N. Castle Susan Dentzer are not yet known, it is clear that con- The markup for the Labor, Health Victor J. Dzau, MD Joseph M. Feczko, MD stituents and advocates have a major and Human Services, Education and Jay A. Gershen, DDS, PhD Carol W. Greider, PhD role to play in determining the out- Related Agencies (LHHS) bill, which Harry Johns Jackie Lovelace Johnson come of these negotiations. The contains funding for NIH, the Evan Jones November 2010 elections brought 108 Centers for Disease Control and Elizabeth Baker Keffer Debra R. Lappin, JD freshman lawmakers to Congress, which Prevention and the Agency for Alan I. Leshner, PhD Lucinda Maine, PhD means they are relying upon con- Healthcare Research and Quality, Mark McClellan, MD, PhD The Honorable Kweisi Mfume stituents and advocates for advice. was postponed until after the August Elizabeth G. Nabel, MD Herbert Pardes, MD Stepping up your advocacy efforts now recess. The LHHS subcommittee was Sudip S. Parikh, PhD is critical in shaping the best possible provided $18 billion less than in FY11 John R. Seffrin, PhD Larry J. Shapiro, MD future for health research. for the markup, and those reductions Ellen Sigal, PhD Laing Rogers Sisto are expected to be reflected in the Christopher A. Viehbacher Appropriations Update Jack T. Watters, MD major accounts, which include NIH Elias A. Zerhouni, MD On July 7, the House Commerce, and Pell Grants. H ONORARY D IRECTOR C. Everett Koop, MD, ScD Justice, Science appropriations subcom- E MERITUS D IRECTORS mittee completed its markup, which The CPH Foundation William G. Anlyan, MD Dennis A. Ausiello, MD was passed by the full appropriations With the Injury Prevention fact sheet Kenneth I. Berns, MD, PhD complete, The CPH Foundation is now William R. Brinkley, PhD committee July 13. The bill provides Roger J. Bulger, MD $6.9 billion for the National Science assessing interest from partner organi- G. Steven Burrill Gail H. Cassell, PhD Foundation in FY12, the same level of zations in developing two new fact Wendy Chaite, Esq. Jordan J. Cohen, MD funding as the previous fiscal year. sheets. Becton, Dickinson and Dominick P. DePaola, DDS, PhD Sam Donaldson The NSF bill cuts the Major Research Company provided The CPH John P. Donnelly Foundation with seed funding to devel- Robert Dresing Equipment and Facilities Construction Eugene Garfield, PhD account by $17 million, but increases op a new fact sheet focused on health Myron Genel, MD Irma E. Goertzen the Research and Related Activities care-associated infections. M.R.C. Greenwood, PhD Elmer E. Huerta, MD, MPH account by $43 million. The Education The CPH Foundation is also working Robert A. Ingram Caroline A. Kovac, PhD and Human Resources account was cut in partnership with the communica- Philip R. Lee, MD Ellen Levine by $26 million. tions office of the CDC’s Office of Constance E. Lieber On May 31, the House Agriculture Public Health Preparedness and John P. Margaritis Jewell Jackson McCabe appropriations subcommittee complet- Response to develop a fact sheet on Catherine E. McDermott Donnica L. Moore, MD ed markup of the bill that provides public health preparedness and James E. Mulvihill, DMD William D. Novelli appropriations for the Food and Drug response. William A. Peck, MD Edward E. Penhoet, PhD William L. Roper, MD, MPH Leon E. Rosenberg, MD Isadore Rosenfeld, MD 2012 FEDERAL RESEARCH BUDGET Raymond R. Sackler, MD Charles A. Sanders, MD Mitchel Sayare, PhD President’s 2012 R!A Carol R. Scheman M. Roy Schwarz, MD Agency C.R. for FY 11 2012 Budget Recommendation Susan C. Scrimshaw, PhD Randolph Siegel National Institutes of Health $30.2 billion $32 billion $35 billion Samuel C. Silverstein, MD Hon. Louis Stokes Centers for Disease Control Hon. Louis W. Sullivan, MD Hon. Billy Tauzin and Prevention* $5.7 billion $6.3 billion $7.7 billion Reed V. Tuckson, MD Alan G. Walton, DSc, PhD National Science Foundation $6.8 billion $7.76 billion $7.76 billion M. Cass Wheeler John Whitehead Phillip L. Williams Agency for Healthcare Ruth Wooden Research and Quality $372 million $397 million $405 million Judy Woodruff James B. Wyngaarden, MD * Reflects the CDC core program budget. 4 research! america Zerhouni Portrait Unveiled at NIH The National Institutes of Health held a ceremony to present former director Elias Zerhouni, MD, with his official portrait, to be hung in one of the institutes. Past and present institute leadership gathered for the ceremony, including NIH Director Francis Collins, MD, PhD, National Institute of Allergy and (Photo courtesy of the National Institutes Health) (Photo courtesy Infectious Diseases Director Francis Collins, MD, PhD, (left); Elias Zerhouni, MD; Harold Varmus, MD; Anthony Fauci, MD; and Nadia Anthony Fauci, MD, and Zerhouni, MD, were all on hand to observe the portrait unveiling for Elias Zerhouni. National Cancer Institute science” during his tenure, Collins said. Africa, a diploma from the University of Director Harold Varmus, MD. The portrait, by artist Steve Algiers and an ancient Arab manuscript. Zerhouni, a Research!America board Craighead, contains elements unique to Zerhouni is now president of global member, had “both heart and spine [as Algerian-born Zerhouni, including the research and development at sanofi, a he] nobly and courageously defended American flag, a globe showing North Research!America member.

Research!America extends special thanks to our principal partners Report: U.S. Lagging in 2011 ADVOCACY AWARD SPONSORS University R&D American Association for Cancer Research (partial support) A report by the Information Tech- Rosenfeld Heart Foundation (benefactor) Whitehead Institute for Biomedical Research (co-benefactor w/Whitehead Foundation) nology and Innovation Foundation found that university research funding Visit www.researchamerica.org/partnership_opportunities for ways to support Research!America. in the U.S. is falling behind that of other industrialized nations.

SPECIAL THANKS TO NEW AND RENEWING RESEARCH!AMERICA ALLIANCE MEMBERS The report found that in 2008, the U.S. ranked 22nd for government- NEW MEMBERS Coalition for Imaging and Bioengineering Research Akron General Medical Center Community Health Charities funded university research, out of 30 Friedreich’s Ataxia Research Alliance Genetics Policy Institute countries tracked by the Organisation Humility of Mary Health Partners Georgetown University Medical Center Jackson Gabriel Silver Foundation Hereditary Disease Foundation for Economic Co-Operation and Kids v Cancer Howard University College of Dentistry Development, slipping from 18th Medical Device Manufacturers Association Infectious Diseases Society of America Northeast Ohio Council on Higher Education Life Technologies place, which it held from 2000-2008. Orexigen Therapeutics The Lymphatic Research Foundation Despite the fact that U.S. invest- WebMD Health Corp. McLaughlin Research Institute ments for university research National Alliance for Eye and Vision Research RENEWING MEMBERS Academy of Radiology Research National Alliance for Hispanic Health increased by 17% as a share of GDP American College of Medical Genetics Nebraska Coalition for Lifesaving Cures invested from 2000-2008, it only National Postdoctoral Association American Dental Education Association amounted to an investment of 0.24% American Heart Association NorTech American Medical Association Northwest Association for Biomedical Research of its total GDP in university-based Oral Health America American Pain Society research in 2008, compared to the American Society of Hypertension Parent Project Muscular Dystrophy Arizona State University College Rice University 0.34% invested by other OECD coun- of Nursing & Health Innovation Society for Pediatric Research tries on average. Association for Psychological Science Union of Concerned Scientists Association of American Cancer Institutes The University of Akron While the U.S. ranks 6th in overall Association of University of California, Berkeley competitiveness, it comes in dead last American Veterinary Medical Colleges University of Cincinnati Association of Schools of Public Health University of Nebraska Medical Center in the rate of change in competitive- AstraZeneca University of North Carolina ness over the last decade, the report Austen BioInnovation Institute in Akron Gillings School of Global Public Health The California Wellness Foundation University of Wisconsin notes. This lack of change, the report Canton Regional Chamber of Commerce School of Medicine and Public Health states, means that the U.S. will trail Case Western Reserve University Whitehead Institute for Biomedical Research School of Dental Medicine Vanderbilt University School of Nursing behind countries that place a higher emphasis on university research. Not yet a member? Join Research!America today at www.researchamerica.org/supportourwork

The research advocate 5 Device Industry Announces Competitiveness Agenda Did Two executives from the medical device industry announced a six-point YOU now K “Competitiveness Agenda,” which aims to streamline regulation and prevent the Research!America was featured in a U.S. from being overtaken as a leader in medical technology. Goldman Sachs report on key take- Stephen J. Ubl, president and CEO of AdvaMed, and Stephen P. MacMillan, chair- aways—specifically the risk of NIH man, president and CEO of Stryker Corporation, unveiled the agenda during a gath- funding cuts in the FY12 budget— ering of civic and business leaders and employees at Stryker’s headquarters in from the American Society for Kalamazoo, MI. Microbiology’s annual meeting. The agenda includes making life sciences innovation a government priority; reform of the Food and Drug Administration device review process; ensuring that *** public and private health insurance payments support medical innovation; reform- The National Institute of General ing trade policy to ensure export growth; strategic tax policies, including improve- Medical Sciences named developmen- ments to the R&D tax credit; and improving America’s R&D infrastructure. tal biologist Judith H. Greenberg, PhD, its acting director. *** FOCR Study Finds More Cancer Drugs Approved For the first time in nearly two decades, More Quickly in U.S. the U.S. government has proposed Friends of Cancer Research released a study showing that approvals of new oncology changes to the “Common Rule.” For drugs are consistently faster and more numerous in the U.S. than in Europe. more, visit http://1.usa.gov/mYFpTU. The study, published in Health Affairs, found that from 2003 to 2010, the Food *** and Drug Administration approved 32 new cancer drugs—six more than its Herbert Pardes, MD, is retiring in European counterpart, the European Medicines Agency. September as head of NewYork- Results of the study also showed that the FDA approved these drugs more quickly, with Presbyterian Hospital and will a median time of 182 days from submission to approval compared to 350 days at EMA. become executive vice chairman of its Further, the drugs examined in the study became available to patients in the U.S. Board of Trustees. Pardes is a earlier than in Europe. Research!America board member. FOCR and Health Affairs are Research!America members.

Judge Dismisses Stem Cell Lawsuit tion shortly thereafter, allowing ESCR A federal judge dismissed a lawsuit Sherley, MD, PhD, and Theresa to resume. That same appellate court that challenged government policy Deisher, PhD, are expected to overturned Lamberth’s injunction in on funding for embryonic stem cell appeal the ruling to the U.S. April, allowing ESCR to continue research. Supreme Court. while Lamberth ruled on the under- Judge Royce C. Lamberth issued In August, Lamberth had ruled in lying merits of the case. the announcement July 27, handing a favor of Sherley and Deisher and The plaintiffs filed the lawsuit victory to the National Institutes of temporarily shut down federally fund- based on the claim that current Health in the case of Sherley v. ed ESCR. The U.S. Court of Appeals ESCR policy violated the Dickey- Sebelius. The plaintiffs, James for the D.C. Circuit issued an injunc- Wicker Amendment.

AMERICA PEAKS Many Americans Say Investment in Regulatory S Science is Important

Regulatory science is a field that develops new tools, standards Very important 38% and approaches to assess the safety, effectiveness, quality and performance of all FDA-regulated products. How important Somewhat important 46% would you say it is that the U.S. invest in advancing regulatory science to make the drug and device development process Not too important 7% more efficient for businesses and safer for patients? Not at all important 3% SOURCE: YOUR CONGRESS–YOUR HEALTH SURVEY, MARCH 2011, Don’t know 6% CHARLTON RESEARCH COMPANY FOR RESEARCH!AMERICA

6 research! america Obama Administration Announces GLOBAL HEALTH National Prevention Strategy President Barack Obama’s administration released its National Prevention Strategy, a framework designed to increase the number of & Americans who are healthy at every stage of life. RDADVOCACY The strategy was developed by the National Prevention, Health Promotion, and Public Health Council, which is comprised of represen- Research!America, the Global Health Council tatives from 17 federal agencies, including Surgeon General Regina and PATH hosted a Capitol Hill briefing June Benjamin, MD, MBA as chair, and Department of Health and Human 6. The event showcased the cost-effectiveness of Services Secretary Kathleen Sebelius. The council consulted with outside vaccines for global health and highlighted how experts and stakeholders to devise the strategy. innovative public- and private-sector research Called for under the Affordable Care Act, the strategy aims to move the and development partnerships can lead to sig- U.S. toward a health care system focused on prevention and includes actions nificant breakthroughs in the global health that public and private partners can take to help Americans stay healthy. arena. Panelists included Lewellys Barker, MD, The framework outlines four strategic directions to improve the senior medical advisor at Aeras; Peter Hotez, nation’s health: building healthy and safe community environments; MD, PhD, president of the Sabin Vaccine expanding quality preventive services in both clinical and community set- Institute; and Marc LaForce, MD, director of tings; empowering people to make healthy choices; and eliminating the Meningitis Vaccine Project at PATH. Eileen health disparities. Quinn of PATH moderated the briefing. All It identifies seven priority areas to achieve these goals: tobacco-free three panelists work for or with product devel- living; preventing drug abuse and excessive alcohol use; healthy eating; opment partnerships (PDPs). These nonprofit active living; injury- and violence-free living; reproductive and sexual organizations work with partners in the public health; and mental and emotional well-being. and private sectors to research, develop and foster access to new health technologies that target diseases disproportionately affecting impover- CDC Global Health Fact Sheet Released ished populations and developing countries. As part of the U.S. Federal Agency and Department Fact Sheet Series, The panelists discussed how PDPs collabo- Research!America has released a fact sheet—this month’s newsletter rate with public- and private-sector partners to insert—highlighting the Centers for Disease Control and Prevention’s develop and deliver vaccines against global contributions to global health research and development. The CDC has a killers, like meningitis, tuberculosis and other presence in every community in the U.S. and employs more than 11,000 neglected diseases of poverty, more efficiently Americans. With a focus on prevention and wellness, the CDC protects the than any one partner could do alone. The PDP health and safety of Americans by tracking and detecting diseases across model saves lives, improves health and can borders, as well as preventing and controlling outbreaks and epidemics. reduce costs over traditional vaccine R&D. The contributions of the CDC to global health were showcased in a recent Increasing vaccination in 72 countries over the media tour of CDC headquarters in Atlanta, hosted by Research!America, next decade would prevent 6.4 million deaths the Campaign for Public Health and the CDC Foundation. Visit and save $6.2 billion in treatment costs, accord- www.researchamerica.org/global_health to download the fact sheet and ing to a recent analysis in Health Affairs. find more resources about the impact of global health R&D.

AMERICA PEAKS Not Enough Support for Military S Health Research

Would you say government support for health research for the benefit of military veterans and Not enough 50% service members is… About right 33% Too much 5%

SOURCE: YOUR CONGRESS–YOUR HEALTH SURVEY, MARCH 2011, Don’t know CHARLTON RESEARCH COMPANY FOR RESEARCH!AMERICA 12%

The research advocate 7 THE

ReADVOCATEsearch 1101 King Street, Suite 520 Alexandria, VA 22314-2960 703-739-2577 phone 703-739-2372 fax www.researchamerica.org 800-366-CURE

Tell Congress: No More ComingUP Advocacy NIH Budget Cuts August 22-23, 2011—The Martin Luther The recent budget deal for FY11 King, Jr. Health Equity Summit, Willard & Intercontinental Hotel, Washington, DC. Action reduced the National Institutes of www.iammm.org/MLKsummit2011_00.html Health budget by over $300 million. The NIH director has reported that grant funding rates for the current fiscal year will be at an all-time low. October 3-5, 2011—2011 World Stem Cell Summit, Pasadena Convention Center, The NIH is critical to our nation’s health, competitiveness and economic Pasadena, CA. www.worldstemcellsummit.com vitality. Act now to tell your representatives in Washington that further cuts to the NIH budget are unacceptable. Our nation needs robust support for health research now more than ever. In addition to sending a message to your representatives, we ask that you pass this information on to others who will speak out in support of health research. The federal budget will continue to be a key issue and we need your help to make our message loud and clear in Washington. To send a message to Congress, please visit www.researchamerica.org/advocacy.

US ON THE WEB Visit www.researchamerica.org Connect with Research!America Online Follow us on Twitter: www.twitter.com/researchamerica Become a fan on Facebook: www.researchamerica.org/facebook Watch our YouTube channel: www.youtube.com/researchamerica Visit our blog: www.researchamerica.org/blog THE CENTERS FOR DISEASE CONTROL AND PREVENTION is present in every local community in the U.S. and has personnel in over 50 countries around the world. In order to protect the health and safety of Americans, the CDC tracks and detects diseases across borders, prevents and controls outbreaks and epidemics, and strengthens our relationships with communities globally through its research and work. 84% of Americans believe that it is important for the federal government to play a role in research for Global Health :: employs more than 11,000 people in the U.S. alone Source: CDC prevention and wellness* Research and :: invested (less than 1% of the total CDC (the focus of the CDC’s Development: $37.6 million budget) in global health research in FY2010 Source: CDC working to global health research improve :: is the largest single donor to global avian flu and efforts) and just as many lives at home pandemic preparedness efforts Source: Congressional Research Service believe that these and abroad. activities reduce health care costs.** “There is widespread recognition of the importance of global health. There is Source: *Your Congress – Your Health Survey, March 2011. Charlton Research Company for bipartisan commitment to making a sustainable and substantial health impact... Research!America **Your Candidates – Your Health Poll, August Prevention must be the core principle that takes global health to the next level.” 2010. Charlton Research Company for Research!America DR. THOMAS FRIEDEN Director, Centers for Disease Control and Prevention

The Meningitis Vaccine Project (MVP) is a product development partnership between PATH (an international nonprofit health organization) and the World Health Organization, created to eliminate epidemic meningitis. Working with the CDC and public and private sector partners, MVP has developed a new affordable vaccine against the most common cause of African epidemics of meningitis, which primarily attacks children and young adults and is often fatal, at less than 50 cents per dose. First introduced in 2010, MenAfriVac could save as much as $300 million if introduced in seven high-risk countries. Widespread use may prevent more than a million cases of F. MARC LAFORCE meningitis over the next decade. Source: http://www.meningvax.org/ DIRECTOR Meningitis Vaccine Project GAVI launched the Accelerated Vaccine Introduction (AVI) initiative in January 2009, a global health partnership between the GAVI Secretariat, the World Health Organization and UNICEF, supported by the CDC, PATH and the Bloomberg School of Public Health at Johns Hopkins University. Pneumonia and diarrheal disease are the world’s two biggest killers of children; through this partnership and accelerated use of rotavirus (the most common cause of severe diarrhea among infants and children) and pneumococcal vaccines, as well as other GAVI supported vaccines, GAVI can immunize nearly 250 million children by 2015 and save four million more lives. Source: http://www.rotavirusvaccine.org/

This fact sheet is part of a series exploring the commitment of U.S. Federal Agencies and Departments to Global Health Research & Development. NIH :: CDC :: DoD:: USAID :: FDA A SMART THING FOR THE U.S. Global Health R&D { THE RIGHT THING FOR THE WORLD.

PARTNERING TO SAVE LIVES Global health R&D partnerships foster success at home and abroad What Americans are saying about the CDC and R&D

Important to Increase Funding for CDC Federal agencies like the Centers for Disease Control and Prevention play a role in improving the health of Americans PARTNERS CDC, Tuberculosis Trial Consortium (TBTC), Vanderbilt University through research and development. LOCATION Brazil, Spain, South Africa, China, Vietnam, Peru How important is it to increase funding GOAL Find new treatments for TB for CDC?

The Tuberculosis Trial Consortium, funded in part by the CDC, is conducting research on new 46% Very important preventive therapies for TB infection. With over 8,000 participants, this partnership recently conducted 37% Somewhat important % the largest TB prevention clinical trial in history, which has yielded promising results. Treatment for TB 8 Not too important 4% Not at all important infections may become simpler (once a week dose instead of daily) and have an overall shorter treatment 5% Don’t know regimen. TB affects 2 billion people worldwide and approximately 11 million people in the United States alone. If successful, new treatment therapies have the potential to prevent the 1.7 million deaths that Source: Your Congress - Your Health Survey, March 2011 Charlton Research Company for Research!America. occur from active TB each year. Source: http://www.cdc.gov/tb/topic/research/tbtc/default.htm

Important for Government Global Health Research and Development Progress to Play a Role in Prevention The Centers for Disease Control and Prevention supports global health R&D that stimulates and Wellness job growth at home, promotes a stable global economy and ensures a safer, healthier world. The CDC’s multiple centers, institutes, and offices all work together to improve health equity and How important is it that the federal health protection worldwide. government plays a role in research for prevention and wellness? The CDC builds capacity and expertise though The CDC conducts critical research that helps eight Global Disease Detection Regional Centers define best practices for programs that aim to 37% Very important around the world. The Centers have discovered eliminate neglected tropical diseases, which 47% Somewhat important and identified 51 unique diseases, and have disproportionately affect the poorest populations 11% Not too important protected more than 103 million people since in the world. 5% Not at all important 2006 through disease surveillance. Source: CDC Budget 2012, p. 221 Source: CDC Budget 2012, p. 220 The CDC conducted research on the President’s Source: Research Enterprise Poll, February 2010 Since 2006, CDC’s Global Disease Detection Emergency Plan for AIDS Relief (PEPFAR) program Charlton Research Company for Research!America. Operations Center (GDDOC) has worked with impact and cost-effectiveness in over 80 ministries of health to develop 185 new diag- countries, leading to revised protocols, cost nostic tests in 59 countries, enabling these savings, and additional lives saved. •••••••• countries to test for diseases that they couldn’t Source: CDC Budget 2012, p. 215 diagnose previously. CDC researchers trained through the Brazilian Source: Morbidity and Mortality Weekly Report, June 24th, 2011; Ten Great Public Health Achievements-Worldwide 2001-2010 Field Epidemiology Training Program assisted in combating Guinea Bissau’s 2008 nationwide The CDC, as part of the Presidential Malaria cholera epidemic, conducting research into the Initiative, conducts research in 17 different efficacy of a new rapid diagnostic test in the field. 1101 King Street, Suite 520 African countries on antimalarial drug resistance Source: State of the CDC Impact Story Topics and treatment/prevention methods. Alexandria, Virginia 22314 Source: CDC Budget 2012, p. 220 703.739.2577 Fax 703.739.2372 Less than one penny of every U.S. health dollar goes toward global health R&D. www.researchamerica.org/global_health