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Translational Science CLOSING THE GAP THROUGH TRANSLATIONAL SCIENCE Elias Zerhouni on Blavatnik Awards Support The Science Behind Breaking Down Barriers Early Career Success Contagion www.nyas.org • Autumn 2011 Board of Governors Chair Vice Chair Treasurer NANCY ZIMPHER KENNETH L. DAVIS ROBERT CATELL President [ex offi cio] Secretary [ex offi cio] ELLIS RUBINSTEIN LARRY SMITH Governors LEN BLAVATNIK ELAINE FUCHS THOMAS CAMPBELL JOHN E. SEXTON MARY BRABECK JAY FURMAN JACKSON GEORGE E. THIBAULT NANCY CANTOR ALICE P. GAST JOHN E. KELLY III PAUL WALKER MARTIN CHALFIE BRIAN GREENE MEHMOOD KHAN IRIS WEINSHALL MILTON COFIELD THOMAS L. HARRISON JEFFREY D. SACHS ANTHONY WELTERS ROBIN L. DAVISSON STEVE HOCHBERG KATHE SACKLER FRANK WILCZEK MIKAEL DOLSTEN TONI HOOVER MORTIMER D.A. SACKLER MICHAEL ZIGMAN International Governors Chairman Emeritus Honorary Life Governors SETH F. BERKLEY RAJENDRA K. PACHAURI TORSTEN N. WIESEL KAREN E. BURKE MANUEL CAMACHO SOLIS RUSSELL READ HERBERT J. KAYDEN GERALD CHAN PAUL STOFFELS JOHN F. NIBLACK S. KRIS GOPALAKRISHNAN President’s Council PETER AGRE AARON CIECHANOVER LEON LEDERMAN PHILLIP A. SHARP Nobel Laureate & Univ. Nobel Laureate & Nobel Laureate & Pritzker Nobel Laureate & Director, Prof. and Director, Johns Distinguished Research Prof., Prof. of Science, Illinois McGovern Inst., MIT Center Hopkins Malaria Research Tumor and Vascular Biology Inst. of Tech.; Resident for Cancer Research Inst., Dept. Molecular Research Center, Faculty of Scholar, Illinois Math & ELLIOTT SIGAL On the cover: Bill Oxford / iStockphoto.com Microbiology and Medicine, Technion-Israel Science Academy CSO, Bristol-Myers Squibb Immunology, Bloomberg Inst. of Tech., Haifa, Israel GREGORY LUCIER MICHAEL SOHLMAN School of Public Health GORDON CONWAY Chairman and CEO, Life Former Exec. Director, The RICHARD AXEL Chair in International Technologies Corporation Nobel Foundation Nobel Laureate & Development, Imperial RODERICK MACKINNON PAUL STOFFELS Professor, Columbia Univ.; College London Nobel Laureate & John Company Group Investigator, HHMI PETER DOHERTY D. Rockefeller, Jr. Prof., Chairman, World Wide LEE BABISS Nobel Laureate & The Rockefeller Univ.; Research & Development, Global Head, Pharma Researcher, St. Jude Investigator, HHMI Pharmaceuticals Group, Executive Editor Research, Roche Children’s Research JOEL S. MARCUS Johnson & Johnson Pharmaceuticals Hospital, Memphis, TN; CEO, Alexandria Real MARC TESSIER-LAVIGNE Diana Friedman DAVID BALTIMORE Univ. of Melbourne Estate Equities, Inc. President, The Rockefeller Univ. Nobel Laureate & President MIKAEL DOLSTEN GERALD J. MCDOUGALL MARY ANN TIGHE Emeritus, Caltech President, Worldwide National Partner, Global CEO, New York Tri-State Art Director ETIENNE-EMILE BAULIEU Research and Development; Pharmaceutical & Health Region, CB Richard Ellis Ash Ayman Shairzay Former President, French Sr. VP, Pfi zer Inc Sciences Practice, SHIRLEY TILGHMAN Academy of Sciences MARCELO EBRARD PricewaterhouseCoopers President, Princeton Univ. PAUL BERG CASAUBÓN LLP FRANK WALSH Contributors Nobel Laureate & Prof. Mayor, Mexico City RICHARD MENSCHEL CEO, Ossianix, Inc. Emeritus, Dept. of EDMOND H. FISCHER Sr. Director, Goldman Sachs GERALD WEISSMANN Douglas Braaten, Sonya Dougal, Biochemistry, Stanford Univ. Nobel Laureate & Prof. RONAY MENSCHEL Prof. of Medicine, NYU Brooke Grindlinger, Jamie Kass, LEN BLAVATNIK Emeritus, Dept. of Chairman of the Board, School of Medicine Chairman, Access Industries Biochemistry, Univ. of Phipps Houses; Board of JOHN WHITEHEAD Stephanie Kelly, Marci A. Landsmann, GÜNTER BLOBEL Washington Overseers, Weill Cornell Former Chairman, Lower Noah Rosenberg, Sarah Webb Nobel Laureate & Director, ALAN J. FRIEDMAN Medical College Manhattan Development Laboratory for Cell Biology, Former Director, New York FERID MURAD Corp.; former Co-Chairman The Rockefeller Univ. Hall of Science Nobel Laureate & Director, of Goldman Sachs Editorial Offi ce IRINA BOKOVA JOSEPH GOLDSTEIN IMM Center for Cell GEORGE WHITESIDES Director General, United Nobel Laureate & Chairman, Signaling, The University of Mallinckrodt Prof. of 7 World Trade Center Nations Educational, Molecular Genetics, Univ. Texas at Houston Chemistry, Harvard Univ. Scientifi c and Cultural of Texas Southwestern JOHN F. NIBLACK TORSTEN N. WIESEL 250 Greenwich St, 40th Fl Organization (UNESCO) Medical Center Former President, Pfi zer Nobel Laureate & former New York, NY 10007-2157 SYDNEY BRENNER S. GOPALAKRISHNAN Global Research & Secy. General, Human Nobel Laureate & Exec. Co-Chairman of the Development Frontier Science Program Phone: 212.298.8645 Distinguished Prof., Salk Inst. Board, Infosys Technologies PAUL NURSE Organization; President Fax: 212.298.3655 MICHAEL S. BROWN Limited Nobel Laureate & President, Emeritus, The Rockefeller Nobel Laureate & Prof. of PAUL GREENGARD The Royal Society; former Univ. Email: [email protected] Molecular Genetics, Univ. Nobel Laureate & Prof. President, The Rockefeller FRANK WILCZEK of Texas Southwestern of Molecular & Cellular Univ. Nobel Laureate & Herman Medical Center Neuroscience, The ROBERT C. RICHARDSON Feshbach Professor of Membership Director LINDA BUCK Rockefeller Univ. Nobel Laureate & Sr. Vice Physics, MIT John F. Grifferty Nobel Laureate & GLENDA GREENWALD Provost for Research, ERNST-LUDWIG Investigator for HHMI; President, Aspen Brain Floyd R. Newman Prof. of WINNACKER member of the Fred Forum Foundation Physics, Cornell Univ. Secy. General, Human Membership & Annals Orders Hutchinson Cancer PETER GRUSS RICHARD ROBERTS Frontier Science Program; Research Center President, Max Planck Nobel Laureate & CSO, former Secy. General, Phone: 212.298.8640 KAREN E. BURKE Gesellschaft, Germany New England Biolabs European Research Council; Fax: 212.298.3650 Dermatologist & Research WILLIAM A. HASELTINE EDWARD F. ROVER former President, Deutsche Scientist President, The Haseltine President, The Dana Forschungsgemeinschaft, Email: [email protected] THOMAS R. CECH Foundation for Medical Foundation Germany Nobel Laureate & Sciences and the Arts; F. SHERWOOD ROWLAND ANDREW WITTY Distinguished Prof., Univ. of Chairman, Haseltine Global Nobel Laureate & Prof. of CEO, GlaxoSmithKline Advertising Inquiries Colorado, Boulder Health, LLC Chemistry & Earth Science, ELIAS ZERHOUNI MARTIN CHALFIE ERIC KANDEL Univ. of California, Irvine President, Global Phone: 212.298.8636 Nobel Laureate & William Nobel Laureate & Prof., BENGT SAMUELSSON Research & Development, Email: [email protected] R. Kenan, Jr., Prof. of Physiology & Cell Biology, Nobel Laureate & Prof., Sanofi -Aventis Biological Sciences; Columbia Univ. Medical & Physiological AHMED ZEWAIL Chair, Dept. of Biological KIYOSHI KUROKAWA Chem., Karolinska Inst.; Nobel Laureate & Linus Visit the Academy online Sciences, Columbia Univ. Former Science Advisor to former Chairman, The Pauling Chair of Chemistry CECILIA CHAN the Prime Minister of Japan; Nobel Foundation and Physics, Caltech www.nyas.org Managing Director, Gold Prof., National Graduate IVAN SEIDENBERG GUANGZHAO ZHOU Avenue Ltd. Institute for Policy Studies Chairman of the Board, Verizon Former Chairman, Chinese (GRIPS) ISMAIL SERAGELDIN Association of Science & Director, Bibliotheca Technology Alexandrina, The Library of Alexandria, Egypt AAutumnutumn 22011011 ccontentsontents Columns Blavatnik Awards 2 Letter from the President 1100 Support System by Sarah Webb Introducing a New Editor Th e Blavatink Awards’ recognition of young scientists has proved critical to their continued success. 4 Annals Highlights Recent and upcoming Annals volumes Cover Story 7 Inside the Academy Reports from the directors of 1166 Closing the Gap through Academy programs and news Translational Science about Academy activities by Diana Friedman Moving from scientifi c discoveries to clinical therapeutics requires better 1133 Academy eBriefi ngs collaboration between scientists and clinicians. Sixth International Congress on Shwachman-Diamond Syndrome, From Crumpling Geometries to Member Memoir Graphene Materials, Trash Talk: Options for Converting Our Solid 2233 Defying Defi nition by Marci A. Landsmann Waste to Energy, Innovating on a Elias Zerhouni discusses his desire to break down artifi cial barriers Shoestring: Medical Technologies in science. for the Developing World 2244 Member News Awards, appointments, and Donor Profi le announcements about Academy 2288 A Medical Education Paradigm members for the Future 2266 Calendar by Noah Rosenberg Academy conferences and George Th ibault and the Josiah Macy Jr. Foundation help the Academy meetings in November, December, push progress. January, and February Letter from the President Introducing a New Editor am donating most of this issue’s From the Editor or VEGF, in angiogenesis, which led to President’s Letter to our dynamic groundbreaking clinical trials for cancer- I new editor, Diana Friedman. She has Dear Members, ous tumors. fearlessly taken on a non-trivial challenge: I am thrilled to introduce myself as What Ferrara and other researchers to improve on the tremendous work of the new editor of Th e New York Acad- gave my father was so much more than a our former editor, Adrienne Burke, who, emy of Sciences Magazine. My goal for drug. It was several months of seemingly through sheer magic, made this magazine this publication is two-fold: 1) to meet healthy, high-quality life, in the midst of intellectually rich and stylistically and vi- your needs for timely and scientifi cal- an otherwise relentless, multi-year dis- sually compelling on a shoestring. ly relevant content and
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