Facial and Palatal Development
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3 Embryology and Development
BIOL 6505 − INTRODUCTION TO FETAL MEDICINE 3. EMBRYOLOGY AND DEVELOPMENT Arlet G. Kurkchubasche, M.D. INTRODUCTION Embryology – the field of study that pertains to the developing organism/human Basic embryology –usually taught in the chronologic sequence of events. These events are the basis for understanding the congenital anomalies that we encounter in the fetus, and help explain the relationships to other organ system concerns. Below is a synopsis of some of the critical steps in embryogenesis from the anatomic rather than molecular basis. These concepts will be more intuitive and evident in conjunction with diagrams and animated sequences. This text is a synopsis of material provided in Langman’s Medical Embryology, 9th ed. First week – ovulation to fertilization to implantation Fertilization restores 1) the diploid number of chromosomes, 2) determines the chromosomal sex and 3) initiates cleavage. Cleavage of the fertilized ovum results in mitotic divisions generating blastomeres that form a 16-cell morula. The dense morula develops a central cavity and now forms the blastocyst, which restructures into 2 components. The inner cell mass forms the embryoblast and outer cell mass the trophoblast. Consequences for fetal management: Variances in cleavage, i.e. splitting of the zygote at various stages/locations - leads to monozygotic twinning with various relationships of the fetal membranes. Cleavage at later weeks will lead to conjoined twinning. Second week: the week of twos – marked by bilaminar germ disc formation. Commences with blastocyst partially embedded in endometrial stroma Trophoblast forms – 1) cytotrophoblast – mitotic cells that coalesce to form 2) syncytiotrophoblast – erodes into maternal tissues, forms lacunae which are critical to development of the uteroplacental circulation. -
Te2, Part Iii
TERMINOLOGIA EMBRYOLOGICA Second Edition International Embryological Terminology FIPAT The Federative International Programme for Anatomical Terminology A programme of the International Federation of Associations of Anatomists (IFAA) TE2, PART III Contents Caput V: Organogenesis Chapter 5: Organogenesis (continued) Systema respiratorium Respiratory system Systema urinarium Urinary system Systemata genitalia Genital systems Coeloma Coelom Glandulae endocrinae Endocrine glands Systema cardiovasculare Cardiovascular system Systema lymphoideum Lymphoid system Bibliographic Reference Citation: FIPAT. Terminologia Embryologica. 2nd ed. FIPAT.library.dal.ca. Federative International Programme for Anatomical Terminology, February 2017 Published pending approval by the General Assembly at the next Congress of IFAA (2019) Creative Commons License: The publication of Terminologia Embryologica is under a Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0) license The individual terms in this terminology are within the public domain. Statements about terms being part of this international standard terminology should use the above bibliographic reference to cite this terminology. The unaltered PDF files of this terminology may be freely copied and distributed by users. IFAA member societies are authorized to publish translations of this terminology. Authors of other works that might be considered derivative should write to the Chair of FIPAT for permission to publish a derivative work. Caput V: ORGANOGENESIS Chapter 5: ORGANOGENESIS -
Selecting Different Approaches for Palate and Pharynx Surgery
SPECIAL ISSUE 4: INVITED ARTICLE Selecting Different Approaches for Palate and Pharynx Surgery: Palatopharyngeal Arch Staging System Rodolfo Lugo-Saldaña1 , Karina Saldívar-Ponce2 , Irina González-Sáez3 , Daniela Hernández-Sirit4 , Patricia Mireles-García5 ABSTRACT The examination of the anatomical structures involved in the upper airway collapse in patients with the obstructive sleep apnea-hypopnea syndrome (OSAHS) is a key for integrated evaluation of patients. Our proposal is for a noninvasive classification system that guides us about the presence of anatomical differences between the palatopharyngeal muscle (PFM). The functions of the PFM are narrowing the isthmus, descending the palate, and raising the larynx during swallowing; these characteristics give the PFM a special role in the collapse of the lateral pharyngeal wall. Complete knowledge of the anatomy and classification of different variants can guide us to choose the appropriate surgical procedures for the lateral wall collapse. Until now there is not a consensus about description of the trajectory or anatomical variants of the PFM into oropharynx, the distance between both muscles, and the muscle tone. Here we also present the relationship between the lateral wall surgeries currently available (lateral pharyngoplasty by Cahali, expansion sphincteroplasty by Pang, relocation pharyngoplasty by Li, Roman blinds pharyngoplasty by Mantovani, and barbed sutures pharyngoplasty by Vicini) with the proposed classification of the palatopharyngeal arch staging system (PASS). Keywords: -
The Evolutionary History of the Human Face
This is a repository copy of The evolutionary history of the human face. White Rose Research Online URL for this paper: https://eprints.whiterose.ac.uk/145560/ Version: Accepted Version Article: Lacruz, Rodrigo S, Stringer, Chris B, Kimbel, William H et al. (5 more authors) (2019) The evolutionary history of the human face. Nature Ecology and Evolution. pp. 726-736. ISSN 2397-334X https://doi.org/10.1038/s41559-019-0865-7 Reuse Items deposited in White Rose Research Online are protected by copyright, with all rights reserved unless indicated otherwise. They may be downloaded and/or printed for private study, or other acts as permitted by national copyright laws. The publisher or other rights holders may allow further reproduction and re-use of the full text version. This is indicated by the licence information on the White Rose Research Online record for the item. Takedown If you consider content in White Rose Research Online to be in breach of UK law, please notify us by emailing [email protected] including the URL of the record and the reason for the withdrawal request. [email protected] https://eprints.whiterose.ac.uk/ THE EVOLUTIONARY HISTORY OF THE HUMAN FACE Rodrigo S. Lacruz1*, Chris B. Stringer2, William H. Kimbel3, Bernard Wood4, Katerina Harvati5, Paul O’Higgins6, Timothy G. Bromage7, Juan-Luis Arsuaga8 1* Department of Basic Science and Craniofacial Biology, New York University College of Dentistry; and NYCEP, New York, USA. 2 Department of Earth Sciences, Natural History Museum, London, UK 3 Institute of Human Origins and School of Human Evolution and Social Change, Arizona State University, Tempe, AZ. -
Effects of Glans Penis Augmentation Using Hyaluronic Acid Gel for Premature Ejaculation
International Journal of Impotence Research (2004) 16, 547–551 & 2004 Nature Publishing Group All rights reserved 0955-9930/04 $30.00 www.nature.com/ijir Effects of glans penis augmentation using hyaluronic acid gel for premature ejaculation JJ Kim1, TI Kwak1, BG Jeon1, J Cheon1 and DG Moon1* 1Department of Urology, Korea University College of Medicine, Sungbuk-ku, Seoul, Korea The main limitation of medical treatment for premature ejaculation is recurrence after withdrawal of medication. We evaluated the effect of glans penis augmentation using injectable hyaluronic acid (HA) gel for the treatment of premature ejaculation via blocking accessibility of tactile stimuli to nerve receptors. In 139 patients of premature ejaculation, dorsal neurectomy (Group I, n ¼ 25), dorsal neurectomy with glandular augmentation (Group II, n ¼ 49) and glandular augmentation (Group III, n ¼ 65) were carried out, respectively. Two branches of dorsal nerve preserving that of midline were cut at 2 cm proximal to coronal sulcus. For glandular augmentation, 2 cc of HA was injected into the glans penis, subcutaneously. At 6 months after each procedure, changes of glandular circumference were measured by tapeline in Groups II and III. In each groups, ejaculation time, patient’s satisfaction and partner’s satisfaction were also assessed. There was no significant difference in preoperative ejaculation time among three groups. Preoperative ejaculation times were 89.2740.29, 101.54759.42 and 96.5752.32 s in Groups I, II and III, respectively. Postoperative ejaculation times were significantly increased to 235.6758.6, 324.247107.58 and 281.9793.2 s in Groups I, II and III, respectively (Po0.01). -
Standard Human Facial Proportions
Name:_____________________________________________ Date:__________________Period: __________________ Standard Human Facial Proportions: The standard proportions for the human head can help you place facial features and find their orientation. The list below gives an idea of ideal proportions. • The eyes are halfway between the top of the head and the chin. • The face is divided into 3 parts from the hairline to the eyebrow, from the eyebrow to the bottom of the nose, and from the nose to the chin. • The bottom of the nose is halfway between the eyes and the chin. • The mouth is one third of the distance between the nose and the chin. • The distance between the eyes is equal to the width of one eye. • The face is about the width of five eyes and about the height of about seven eyes. • The base of the nose is about the width of the eye. • The mouth at rest is about the width of an eye. • The corners of the mouth line up with the centers of the eye. Their width is the distance between the pupils of the eye. • The top of the ears line up slightly above the eyes in line with the outer tips of the eyebrows. • The bottom of the ears line up with the bottom of the nose. • The width of the shoulders is equal to two head lengths. • The width of the neck is about ½ a head. Facial Feature Examples.docx Page 1 of 13 Name:_____________________________________________ Date:__________________Period: __________________ PROFILE FACIAL PROPORTIONS Facial Feature Examples.docx Page 2 of 13 Name:_____________________________________________ Date:__________________Period: -
Embryology8 Dr.Ban Facial, Nasal and Palatal Development the External Human Face Develops Between the 4Th and 6Th Weeks of Embryonic Development
Embryology8 Dr.Ban Facial, nasal and palatal development The external human face develops between the 4th and 6th weeks of embryonic development. Facial swellings arise on: -Frontonasal process (2 medial nasal and 2 lateral nasal processes) -First pharyngeal arch (2 mandibular and 2 maxillary processes). By a process of merging and some localized fusion these processes come together to form the continuous surfaces of the external face. Sequence of developmental events : During the 3rd week of development an oropharyngeal membrane (buccopharyngeal ) is first seen at the site of the future face, between the primordium of the heart and the rapidly enlarging primordium of the brain. It is composed of ectoderm externally and endoderm internally. It lies at the beginning of the digestive tract and breaks down during the 4th week in order to form the opening between the future oral cavity (primitive mouth or stomodeum) and the foregut. The oropharyngeal membrane breaks down when it stops growing and it’s non-proliferating cells are gradually pulled apart 1 because they cannot fill the expanding area.The tissues around it expand very rapidly. The face develops from five primordia that appear in the fourth week: the frontonasal prominence, the two maxillary swellings, and the two mandibular swellings. The external face forms from two sources that surround the oropharyngeal membrane 1-Tissues of the frontonasal process that cover the forebrain, predominantly of neural crest origin. 2-The tissues of the first (or mandibular) pharyngeal arch, of mixed mesoderm and neural crest origin Face initially formed by 5 mesenchymal swellings ( prominences): Two mandibular prominences Two maxillary prominences Frontonasal prominence (midline structure is a single structure that is ventral to the forebrain. -
Vocabulario De Morfoloxía, Anatomía E Citoloxía Veterinaria
Vocabulario de Morfoloxía, anatomía e citoloxía veterinaria (galego-español-inglés) Servizo de Normalización Lingüística Universidade de Santiago de Compostela COLECCIÓN VOCABULARIOS TEMÁTICOS N.º 4 SERVIZO DE NORMALIZACIÓN LINGÜÍSTICA Vocabulario de Morfoloxía, anatomía e citoloxía veterinaria (galego-español-inglés) 2008 UNIVERSIDADE DE SANTIAGO DE COMPOSTELA VOCABULARIO de morfoloxía, anatomía e citoloxía veterinaria : (galego-español- inglés) / coordinador Xusto A. Rodríguez Río, Servizo de Normalización Lingüística ; autores Matilde Lombardero Fernández ... [et al.]. – Santiago de Compostela : Universidade de Santiago de Compostela, Servizo de Publicacións e Intercambio Científico, 2008. – 369 p. ; 21 cm. – (Vocabularios temáticos ; 4). - D.L. C 2458-2008. – ISBN 978-84-9887-018-3 1.Medicina �������������������������������������������������������������������������veterinaria-Diccionarios�������������������������������������������������. 2.Galego (Lingua)-Glosarios, vocabularios, etc. políglotas. I.Lombardero Fernández, Matilde. II.Rodríguez Rio, Xusto A. coord. III. Universidade de Santiago de Compostela. Servizo de Normalización Lingüística, coord. IV.Universidade de Santiago de Compostela. Servizo de Publicacións e Intercambio Científico, ed. V.Serie. 591.4(038)=699=60=20 Coordinador Xusto A. Rodríguez Río (Área de Terminoloxía. Servizo de Normalización Lingüística. Universidade de Santiago de Compostela) Autoras/res Matilde Lombardero Fernández (doutora en Veterinaria e profesora do Departamento de Anatomía e Produción Animal. -
Abbreviations - Diagnosis
Abbreviations - Diagnosis AB abrasion AT attrition CA caries CFL cleft lip CFP cleft palate CLL cervical line lesion - See TR CMO craniomandibular osteopathy DT deciduous (primary) tooth DTC dentigerous cyst E enamel E/D enamel defect E/H enamel hypocalcification or hypoplasia FB foreign body FORL feline odontoclastic resorptive lesion - See TR FX fracture (tooth or jaw) G granuloma G/B buccal granuloma (cheek chewing lesion) G/L sublingual granuloma (tongue chewing lesion) G/E/L eosinophilic granuloma - lip G/E/P eosinophilic granuloma - palate G/E/T eosinophilic granuloma - tongue GH gingival hyperplasia GR gingival recession LAC laceration LAC/B laceration buccal (cheek) LAC/L laceration lip LAC/T laceration tongue MAL malocclusion MAL/1 class 1 malocclusion (neutroclusion - normal jaw relationship, specific teeth are incorrectly positioned) MAL/2 class 2 malocclusion (mandibular distoclusion - mandible shorter than maxilla) MAL/3 class 3 malocclusion (mandibular mesioclusion - maxilla shorter than mandible) BV buccoversion (crown directed towards cheek) CXB caudal crossbite DV distoversion (crown directed away from midline of dental arch) LABV labioversion (crown directed towards lip) LV linguoversion (crown directed towards tongue) MV mesioversion (crown directed towards midline of dental arch) OB open bite RXB rostral crossbite MN mandible or mandibular MN/FX mandibular fracture MX maxilla or maxillary MX/FX maxillary fracture OM oral mass OM/AD adenocarcinoma OM/EPA acanthomatous ameloblastoma (epulis) OM/EPF fibromatous epulis -
Angina Bullosa Haemorrhagica (Oral Blood Blister) (PDF)
Patient Information Maxillo-facial Angina Bullosa Haemorrhagica (Oral Blood Blister) What is Angina Bullosa Haemorrhagica? Angina Bullosa Hemorrhagica (ABH) is a condition where an often painful, but benign blood-filled blister suddenly develops in the mouth. The blisters are generally not due to a blood clotting disorder or any other medical disorder. It is a fairly common, sudden onset and benign blood blistering oral (mouth) disorder. It mainly affects people over 45 years and both males and females are equally affected. Usually there is no family history of the condition. It may be associated with Type 2 Diabetes, a family history of diabetes or Hyperglycaemia. What are the signs and symptoms of ABH? The first indication is a stinging pain or burning sensation just before the appearance of a blood blister The blisters last only a few minutes and then spontaneously rupture (burst), leaving a shallow ulcer that heals without scarring, discomfort or pain They can reach an average size of one to three centimetres in diameter The Soft Palate (back of the mouth) is the most affected site If they occur on the palate and are relatively big, they may need to be de-roofed (cut and drained) to ease the sensation of choking Patient Information Occasionally blisters can occur in the buccal mucosa (cheek) and tongue Approximately one third of the patients have blood blisters in more than one location. What are the causes of ABH? More than 50% of cases are related to minor trauma caused by: hot foods, restorative dentistry (fillings, crowns etc) or Periodontal Therapy (treatment of gum disease). -
Embryology of Branchial Region
TRANSCRIPTIONS OF NARRATIONS FOR EMBRYOLOGY OF THE BRANCHIAL REGION Branchial Arch Development, slide 2 This is a very familiar picture - a median sagittal section of a four week embryo. I have actually done one thing correctly, I have eliminated the oropharyngeal membrane, which does disappear sometime during the fourth week of development. The cloacal membrane, as you know, doesn't disappear until the seventh week, and therefore it is still intact here, but unlabeled. But, I've labeled a couple of things not mentioned before. First of all, the most cranial part of the foregut, that is, the part that is cranial to the chest region, is called the pharynx. The part of the foregut in the chest region is called the esophagus; you probably knew that. And then, leading to the pharynx from the outside, is an ectodermal inpocketing, which is called the stomodeum. That originally led to the oropharyngeal membrane, but now that the oropharyngeal membrane is ruptured, the stomodeum is a pathway between the amniotic cavity and the lumen of the foregut. The stomodeum is going to become your oral cavity. Branchial Arch Development, slide 3 This is an actual picture of a four-week embryo. It's about 5mm crown-rump length. The stomodeum is labeled - that is the future oral cavity that leads to the pharynx through the ruptured oropharyngeal membrane. And I've also indicated these ridges separated by grooves that lie caudal to the stomodeum and cranial to the heart, which are called branchial arches. Now, if this is a four- week old embryo, clearly these things have developed during the fourth week, and I've never mentioned them before. -
Vestibule Lingual Frenulum Tongue Hyoid Bone Trachea (A) Soft Palate
Mouth (oral cavity) Parotid gland Tongue Sublingual gland Salivary Submandibular glands gland Esophagus Pharynx Stomach Pancreas (Spleen) Liver Gallbladder Transverse colon Duodenum Descending colon Small Jejunum Ascending colon intestine Ileum Large Cecum intestine Sigmoid colon Rectum Appendix Anus Anal canal © 2018 Pearson Education, Inc. 1 Nasopharynx Hard palate Soft palate Oral cavity Uvula Lips (labia) Palatine tonsil Vestibule Lingual tonsil Oropharynx Lingual frenulum Epiglottis Tongue Laryngopharynx Hyoid bone Esophagus Trachea (a) © 2018 Pearson Education, Inc. 2 Upper lip Gingivae Hard palate (gums) Soft palate Uvula Palatine tonsil Oropharynx Tongue (b) © 2018 Pearson Education, Inc. 3 Nasopharynx Hard palate Soft palate Oral cavity Uvula Lips (labia) Palatine tonsil Vestibule Lingual tonsil Oropharynx Lingual frenulum Epiglottis Tongue Laryngopharynx Hyoid bone Esophagus Trachea (a) © 2018 Pearson Education, Inc. 4 Visceral peritoneum Intrinsic nerve plexuses • Myenteric nerve plexus • Submucosal nerve plexus Submucosal glands Mucosa • Surface epithelium • Lamina propria • Muscle layer Submucosa Muscularis externa • Longitudinal muscle layer • Circular muscle layer Serosa (visceral peritoneum) Nerve Gland in Lumen Artery mucosa Mesentery Vein Duct oF gland Lymphoid tissue outside alimentary canal © 2018 Pearson Education, Inc. 5 Diaphragm Falciform ligament Lesser Liver omentum Spleen Pancreas Gallbladder Stomach Duodenum Visceral peritoneum Transverse colon Greater omentum Mesenteries Parietal peritoneum Small intestine Peritoneal cavity Uterus Large intestine Cecum Rectum Anus Urinary bladder (a) (b) © 2018 Pearson Education, Inc. 6 Cardia Fundus Esophagus Muscularis Serosa externa • Longitudinal layer • Circular layer • Oblique layer Body Lesser Rugae curvature of Pylorus mucosa Greater curvature Duodenum Pyloric Pyloric sphincter antrum (a) (valve) © 2018 Pearson Education, Inc. 7 Fundus Body Rugae of mucosa Pyloric Pyloric (b) sphincter antrum © 2018 Pearson Education, Inc.