Anti-CX3CR1 Monoclonal Antibody, Clone 9F21.E0 (DCABH-7911) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-CX3CR1 monoclonal antibody, clone 9F21.E0 (DCABH-7911) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal to CX3CR1

Antigen Description Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1.

Immunogen Synthetic peptide corresponding to Human CX3CR1 aa 207-222 conjugated to Keyhole Limpet Haemocyanin (KLH).Sequence: MSYCYFRIIQTLFSCK Database link: P49238

Isotype IgG1

Source/Host Mouse

Species Reactivity Human

Clone 9F21.E0

Purity Protein G purified

Conjugate Unconjugated

Applications IHC-P, WB

Positive Control Human brain tissue; Human spleen lysate.

Format Liquid

Size 50 μl

Buffer Constituent: 100% PBS

Preservative None

Storage Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

Ship Shipped at 4°C.

GENE INFORMATION

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Official Symbol CX3CR1

Synonyms CX3CR1; chemokine (C-X3-C motif) receptor 1; chemokine (C X3 C) receptor 1 , CMKBRL1, GPR13; CX3C chemokine receptor 1; CCRL1; CMKDR1; V28; CMK-BRL1; CMK-BRL-1; C-X3-C CKR-1; fractalkine receptor; G protein-coupled receptor 13; G-protein coupled receptor

Entrez Gene ID 1524

Protein Refseq NP_001164642

UniProt ID P49238

Chromosome Location 3p21.3

Pathway Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; GPCR ligand binding, organism-specific biosystem.

Function C-X3-C chemokine receptor activity; G-protein coupled receptor activity; chemokine receptor activity; protein binding; receptor activity; signal transducer activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]