Anti-CX3CR1 monoclonal antibody, clone 9F21.E0 (DCABH-7911) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Product Overview Mouse monoclonal to CX3CR1 Antigen Description Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1. Immunogen Synthetic peptide corresponding to Human CX3CR1 aa 207-222 conjugated to Keyhole Limpet Haemocyanin (KLH).Sequence: MSYCYFRIIQTLFSCK Database link: P49238 Isotype IgG1 Source/Host Mouse Species Reactivity Human Clone 9F21.E0 Purity Protein G purified Conjugate Unconjugated Applications IHC-P, WB Positive Control Human brain tissue; Human spleen lysate. Format Liquid Size 50 μl Buffer Constituent: 100% PBS Preservative None Storage Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Ship Shipped at 4°C. GENE INFORMATION 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Gene Name CX3CR1 chemokine (C-X3-C motif) receptor 1 [ Homo sapiens ] Official Symbol CX3CR1 Synonyms CX3CR1; chemokine (C-X3-C motif) receptor 1; chemokine (C X3 C) receptor 1 , CMKBRL1, GPR13; CX3C chemokine receptor 1; CCRL1; CMKDR1; V28; CMK-BRL1; CMK-BRL-1; C-X3-C CKR-1; fractalkine receptor; G protein-coupled receptor 13; G-protein coupled receptor Entrez Gene ID 1524 Protein Refseq NP_001164642 UniProt ID P49238 Chromosome Location 3p21.3 Pathway Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; GPCR ligand binding, organism-specific biosystem. Function C-X3-C chemokine receptor activity; G-protein coupled receptor activity; chemokine receptor activity; protein binding; receptor activity; signal transducer activity; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.