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2017 National Veterinary Scholars Symposium 18th Annual August – 4 5, 2017 Natcher Conference Center, Building 45 National Institutes of Health Bethesda, Maryland Center for Cancer Research National Cancer Institute with The Association of American Veterinary Medical Colleges https://www.cancer.gov/ Table of Contents 2017 National Veterinary Scholars Symposium Program Booklet Welcome .............................................................................................................................. 1 NIH Bethesda Campus Visitor Information and Maps .........................................................2 History of the National Institutes of Health ......................................................................... 4 Sponsors ............................................................................................................................... 5 Symposium Agenda .......................................................................................................6 Bios of Speakers ................................................................................................................. 12 Bios of Award Presenters and Recipients ........................................................................... 27 Training Opportunities at the NIH ...................................................................................... 34 Abstracts Listed Alphabetically .......................................................................................... 41 Symposium Participants by College of Veterinary Medicine ..............................................61 Complete Abstracts (listed alphabetically) ......................................................................... 73 All Abstract Titles and Posters are listed on the event website: https://aavmc.z2systems.com/np/clients/aavmc/event.jsp?event=67& 1 NIH Bethesda Campus Visitor Access and Parking Information All visitors must enter campus through the NIH Gateway Center. You will be asked to submit to a vehicle or personal inspection and must provide a form of government-issued photo ID such as a driver's license or passport. Visitors are encouraged to use public transportation such as the Metrorail system which has a convenient stop on the Red Line (Medical Center) for the NIH campus. The Hyatt Hotel is located at the Bethesda Metro Stop. The NIH Gateway Center is located adjacent to the Medical Center Metro Station at the South Drive entrance to campus from Rockville Pike (Rte. 355). It combines visitor parking, non-commercial vehicle inspection and visitor ID processing, all in one location. The Gateway complex includes MLP-11, a multi- level underground parking garage. This visitor-only lot is the primary visitor parking for the NIH campus. Vehicles parking in MLP-11 are outside of the perimeter security and will not go through vehicle inspection, reducing the amount of time it takes to get on campus. The cost to park in MLP-11 on Friday is $2.00 per hour for the first three hours, $12.00 maximum for the entire day. Saturday parking is free. Visitors parking in MLP-11 should proceed to the Gateway Center to get a visitor badge and take a short walk (or take a shuttle bus) to their destination. Vehicles left in the MLP-11 parking garage after 11pm on weekdays or during weekends are subject to ticketing and towing. MLP-11 is closed on Saturdays. When MLP-11 is closed, visitors can park in visitor lots on the main campus. (See Full Campus Map on Following Page) 2 NIH Bethesda Campus Map Note: Visitor Parking in GREEN NIH Gateway Center for Visitors is located adjacent to the Medical Center Metro Station at the South Drive entrance to campus from Rockville Pike (Route 355). 3 A Brief History of the National Institutes of Health (NIH) The National Institutes of Health is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s. It is part of the U.S. Department of Health and Human Services. The NIH comprises 27 separate institutes and centers with approximately 20,262 employees. In the late 1870s, Congress allocated funds to investigate the causes of epidemics like cholera and yellow fever, and it created the National Board of Health, making medical research an official government initiative. In 1930, Congress introduced the "Ransdell Act" to establish and operate a National Institute of Health, to create a system of fellowships in said institute, and to authorize the Government to accept donations for use in ascertaining the cause, prevention, and cure of disease affecting human beings, and for other purposes. Over the next few decades, Congress would increase its funding tremendously to the NIH, and various institutes and centers within the NIH were created for specific research programs. In 1944, the Public Health Service Act was approved, and the National Cancer Institute became a division of NIH. In 1948, the name changed from National Institute of Health to National Institutes of Health. By 1971, cancer research was in full force and President Nixon signed the National Cancer Act, initiating a National Cancer Program, National Cancer Advisory Board, and 15 new research, training, and demonstration centers. During the 1990s, the NIH committee focus shifted to DNA research and the Human Genome Project was launched. More current research initiatives include the 21st Century Cures Act, the BRAIN initiative, Cancer Moonshot, and many others. For over a century, NIH scientists have paved the way for important discoveries that improve health and save lives. In fact, 148 Nobel Prize winners have received support from NIH. The NIH conducts its own scientific research through its Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. NIH devotes 10% of its funding to research within its own facilities (intramural research). The institution gives 80% of its funding in research grants to extramural (outside) researchers. The extramural funding consists of about 50,000 grants to more than 325,000 researchers at more than 3,000 institutions. 4 2017 National Veterinary Scholars Symposium Meeting Sponsors 5 2017 National Veterinary Scholars Symposium Center for Cancer Research, National Cancer Institute National Institutes of Health Bethesda, Maryland With The Association of American Veterinary Medical Colleges Washington, D.C. August 4 – 5, 2017 Symposium Schedule Friday, August 4, 2017 Scientific Sessions, NIH Bethesda Campus, Natcher Conference Center, Building 45 TIME ROOM/ LOCATION 7:00AM – Registration Natcher Center, 8:00AM Lower Lobby 7:00AM – Breakfast and Posters set up by 7:55AM Natcher Center Atrium 8:00AM (Posters displayed side by side even and odd numbers) and Rooms E1/E2, F1/F2, and G1/G2 8:05AM – Welcome! To NIH Natcher Auditorium 8:20AM Michael M. Gottesman, M.D. and Balcony A, B, C Deputy Director for Intramural Research, Office of the Director, National Institutes of Health, and Senior Investigator, Multidrug Resistance Section Head, and Chief, Laboratory of Cell Biology Center for Cancer Research, National Cancer Institute Session Introductions and meeting host: R. Mark Simpson, D.V.M., Ph.D. Senior Scientist and Head, Molecular Pathology Unit Director, Comparative Biomedical Scientist Training Program Laboratory of Cancer Biology and Genetics Center for Cancer Research, National Cancer Institute 8:20AM – Fabian M. Kausche, MS, Dr med vet Natcher Auditorium 8:30AM Head of Global Research and Development, (10 min) Animal Health Business Unit Boehringer Ingelheim, Duluth, GA “A History of the National Veterinary Scholars Symposium” Plenary Session – Global Health 8:30AM – Julie Pavlin, M.D., Ph.D., MPH Natcher Auditorium 9:20AM Director, Board on Global Health (50 min) National Academies of Sciences, Engineering and Medicine, Washington, D.C. “Global Health, Emerging Infections and One Health” 9:20AM – Corrie Brown, D.V.M., Ph.D. Natcher Auditorium 10:10AM Josiah Meigs and University Distinguished Professor 6 2017 National Veterinary Scholars Symposium Center for Cancer Research, National Cancer Institute National Institutes of Health Bethesda, Maryland With The Association of American Veterinary Medical Colleges Washington, D.C. August 4 – 5, 2017 Symposium Schedule Friday, August 4, 2017 continued (50 min) College of Veterinary Medicine, University of Georgia, Athens, GA “Lessons and Lesions from Around the World” 10:10AM – Panel Discussion 10:20AM (10 min) 10:20AM – Break 10:30AM (10 min) 10:30AM – Student Poster Session A (Even Numbers) Natcher Center Atrium 12:00PM and Rooms E1/E2, (90 min) F1/F2, and G1/G2 12:00PM – Lunch 1:00PM (60 min) 1:00PM – Student Poster Session B (Odd Numbers) Natcher Center Atrium 2:30PM and Rooms E1/E2, (90 min) F1/F2, and G1/G2 Plenary Session – Neuroscience and Genetics 2:30PM – Hugo Bellen, D.V.M., Ph.D. Natcher Auditorium 3:20PM Howard Hughes Medical Institute Investigator (50 min) Professor, Department of Molecular and Human Genetics Baylor College of Medicine, Houston, TX “Drosophila to Identify and Unravel Pathogenic Mechanisms of Human Diseases” 3:20PM – R. Douglas Fields, Ph.D. Natcher Auditorium 4:10PM Senior Investigator and Chief (50 min) Nervous System Development and Plasticity Section National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD “Beyond the Neuron Doctrine: White Matter Plasticity in Response to Functional Activity” 4:10PM – Panel Discussion 4:20PM (10
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