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Homage to Gaia
Homage to Gaia The Life of an Independent Scientist James Lovelock Souvenir Press I dedicate this book to my beloved wife Sandy This paperback published in 2019 First published by Souvenir Press in 2014, an imprint of Profile Books Ltd 3 Holford Yard Bevin Way London WC1X 9HD www.profilebooks.com First published in Great Britain in 2000 by Oxford University Press Copyright © 2000, 2013 by J.E. Lovelock Copyright © 2000, 2013, 2019 by J. E. Lovelock First published in 2000 by Oxford University Press The right of James Lovelock to be identified as the author of this work has been Thisasserted second in accordance paperback withedition section published 77 of thein 2014 Copyright, by Souvenir Designs Press and Ltd Patents Act, 431988 Great Russell Street, London WC1B 3PD All rights reserved. No part of this publication may be reproduced, stored in a Theretrieval right system of James or Lovelocktransmitted, to be in identifiedany form oras bythe any means, electronic, mechanical, authorphotocopying, of this work or otherwise, has been withoutasserted the in accordanceprior permission with of the Copyright owner. section 77 of the Copyright, Designs and Patents Act, 1988 ISBN 978 1 78816 460 3 All rights reserved. No part of this publication may be reproduced, eISBN 978 0 28564 256 0 stored in a retrieval system or transmitted, in any form or by any means, electronic, mechanical, photocopying, or otherwise, withoutPrinted andthe priorbound permission in Great Britain of the byCopyright owner. CPI Group (UK) Ltd, Croydon, CRO 4YY ISBN 9780285642553 Offset from the Oxford University Press edition of ‘Homage to Gaia: The Life of an Independent Scientist’ by James Lovelock. -
Mothers in Science
The aim of this book is to illustrate, graphically, that it is perfectly possible to combine a successful and fulfilling career in research science with motherhood, and that there are no rules about how to do this. On each page you will find a timeline showing on one side, the career path of a research group leader in academic science, and on the other side, important events in her family life. Each contributor has also provided a brief text about their research and about how they have combined their career and family commitments. This project was funded by a Rosalind Franklin Award from the Royal Society 1 Foreword It is well known that women are under-represented in careers in These rules are part of a much wider mythology among scientists of science. In academia, considerable attention has been focused on the both genders at the PhD and post-doctoral stages in their careers. paucity of women at lecturer level, and the even more lamentable The myths bubble up from the combination of two aspects of the state of affairs at more senior levels. The academic career path has academic science environment. First, a quick look at the numbers a long apprenticeship. Typically there is an undergraduate degree, immediately shows that there are far fewer lectureship positions followed by a PhD, then some post-doctoral research contracts and than qualified candidates to fill them. Second, the mentors of early research fellowships, and then finally a more stable lectureship or career researchers are academic scientists who have successfully permanent research leader position, with promotion on up the made the transition to lectureships and beyond. -
Society for Developmental Biology 64Th Annual Meeting
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Elsevier - Publisher Connector Developmental Biology 283 (2005) 537 – 574 www.elsevier.com/locate/ydbio Society for Developmental Biology 64th Annual Meeting Hyatt Regency, San Francisco, CA July 27–August 1, 2005 Organizing Committee: Judith Kimble (Chair, SDB President), Kathy Barton, Minx Fuller, Nipam Patel, Didier Stainier, Xin Sun, Bill Wood Local Organizers: Didier Stainier, Ida Chow Numbers in italics are program abstract numbers and names in bold are speakers. Poster assignments are listed at the end of the meeting program. Program Wednesday, July 27 9 am–5 pm Satellite Symposia (not organized by SDB) Segmentation Seacliff AB Co-organizers: Kenro Kusumi and Olivier Pourquie´ Molecular Biology of Plant Development Seacliff CD Organizer: Kathy Barton 12–7 pm Meeting Registration Grand Foyer Poster Session I and Exhibits Set-up Pacific Concourse See poster assignments at the end of the program 7–9 pm President’s Symposium Grand Ballroom Fundamental Problems of Developmental Biology Chair: Judith Kimble, University of Wisconsin-Madison and HHMI, Madison, WI 7:00 The soma-germline dichotomy. G. Seydoux. Johns Hopkins University, Baltimore, MD 1 7:40 MicroRNAs and their regulatory roles in plants and animals. D.P. Bartel. MIT and Whitehead Institute for Biomedical Research, Cambridge, MA 8:20 The genetics and genomics of evolving new traits in vertebrates. D. Kingsley. Stanford University and HHMI, Stanford, CA 9–11 pm Opening Reception in Honor of Eric Olson, Pacific Concourse Developmental Biology Editor-in-Chief, for invaluable service to the community Poster Session I and Exhibits Pacific Concourse See poster assignments at the end of the program YDBIO-02007; No. -
Gurdon Institute 20122011 PROSPECTUS / ANNUAL REPORT 20112010
The Wellcome Trust/Cancer Research UK Gurdon Institute 20122011 PROSPECTUS / ANNUAL REPORT 20112010 Gurdon I N S T I T U T E PROSPECTUS 2012 ANNUAL REPORT 2011 http://www.gurdon.cam.ac.uk CONTENTS THE INSTITUTE IN 2011 INTRODUCTION........................................................................................................................................3 HISTORICAL BACKGROUND..........................................................................................................4 CENTRAL SUPPORT SERVICES....................................................................................................5 FUNDING.........................................................................................................................................................5 RETREAT............................................................................................................................................................5 RESEARCH GROUPS.........................................................................................................6 MEMBERS OF THE INSTITUTE................................................................................44 CATEGORIES OF APPOINTMENT..............................................................................44 POSTGRADUATE OPPORTUNITIES..........................................................................44 SENIOR GROUP LEADERS.............................................................................................44 GROUP LEADERS.......................................................................................................................48 -
FOI Ref 6871 Response Sent 17 March Can You Please Provide The
FOI Ref 6871 Response sent 17 March Can you please provide the following details from the most recent records which you hold under The Licensing Act 2003: On-trade alcohol licensed premises, including: Premises Licence Number Date Issued Premises Licence Status (active, expired etc.) Premises Name Premises Address Premises Postcode Premises Telephone Number Premises on-trade Category (e.g. Cafe, Bar, Theatre, Nightclub etc.) Premises Licence Holder Name Premises Licence Holder Address Premises Licence Holder Postcode Designated Premises Supervisor Name Designated Premises Supervisor Address Designated Premises Supervisor Postcode The information you have requested is held and in the attached. However the personal information relating to Designated Premises Supervisors you have requested is refused under the exemption to disclosure at Section 40(2) of the Act Further queries on this matter should be directed to [email protected] Full address Telephone number Licence type Status Date issued Licence holder 1 and 1 Rougamo Ltd, 84 Regent Street, Cambridge, 07730029914 Premises Licence Current Licence 10/03/2020 Yao Qin Cambridgeshire, CB2 1DP 2648 Cambridge, 14A Trinity Street, Cambridge, 01223 506090 Premises Licence Current Registration 03/10/2005 The New Vaults Limited Cambridgeshire, CB2 1TB 2nd View Cafe - Waterstones, 20-22 Sidney Street, Premises Licence Current Registration 17/09/2010 Waterstones Booksellers Ltd Cambridge, Cambridgeshire, CB2 3HG ADC Theatre, Park Street, Cambridge, Cambridgeshire, CB5 01223 359547 Premises Licence -
Gurdon Institute 2010 PROSPECTUS / ANNUAL REPORT 2009
The Wellcome Trust/Cancer Research UK Gurdon Institute 2010 PROSPECTUS / ANNUAL REPORT 2009 Gurdon I N S T I T U T E PROSPECTUS 2010 ANNUAL REPORT 2009 http://www.gurdon.cam.ac.uk THE GURDON INSTITUTE 1 CONTENTS THE INSTITUTE IN 2009 INTRODUCTION....................................................................................................................3 HISTORICAL BACKGROUND..........................................................................................................4 CENTRAL SUPPORT SERVICES....................................................................................................4 FUNDING...........................................................................................................................................4 RETREAT.................................................................................................................................................5 RESEARCH GROUPS.........................................................................................................6 MEMBERS OF THE INSTITUTE................................................................................38 CATEGORIES OF APPOINTMENT..............................................................................38 POSTGRADUATE OPPORTUNITIES..........................................................................38 SENIOR GROUP LEADERS.............................................................................................38 GROUP LEADERS.......................................................................................................................45 -
Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6
Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6 The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Citation Lee, Joo-Hyeon et al. “Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6.” Cell 170, 6 (September 2017): 1149–1163 © 2017 The Authors As Published http://dx.doi.org/10.1016/J.CELL.2017.07.028 Publisher Elsevier BV Version Final published version Citable link http://hdl.handle.net/1721.1/116555 Terms of Use Creative Commons Attribution 4.0 International License Detailed Terms http://creativecommons.org/licenses/by/4.0/ Article Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6 Graphical Abstract Authors Joo-Hyeon Lee, Tuomas Tammela, Matan Hofree, ..., Tyler Jacks, Aviv Regev, Carla F. Kim Correspondence [email protected] (J.-H.L.), [email protected] (C.F.K.) In Brief Heterogeneous mesenchymal cell populations in the lung play a central role in epithelial maintenance and alveolar differentiation. Highlights d Lgr5 and Lgr6 mark mesenchymal cells in adult lungs d Single-cell transcriptome analysis defines mesenchymal heterogeneity d Distinct mesenchymal niches drive airway and alveolar differentiation d Wnt activity affects epithelial differentiation specified by mesenchymal cells Lee et al., 2017, Cell 170, 1149–1163 September 7, 2017 ª 2017 The Authors. Published by Elsevier Inc. http://dx.doi.org/10.1016/j.cell.2017.07.028 Article Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6 Joo-Hyeon Lee,1,2,3,4,5,* Tuomas Tammela,6 Matan Hofree,7 Jinwook Choi,4 Nemanja Despot Marjanovic,6 Seungmin Han,4,8 David Canner,6 Katherine Wu,6 Margherita Paschini,1,2,3 Dong Ha Bhang,9 Tyler Jacks,6,10 Aviv Regev,6,7,10 and Carla F. -
Mechanistic Insights and Identification of Two Novel Factors in the C
Downloaded from genesdev.cshlp.org on September 24, 2021 - Published by Cold Spring Harbor Laboratory Press Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway Dasa Longman,1 Ronald H.A. Plasterk,2 Iain L. Johnstone,3 and Javier F. Cáceres1,4 1Medical Research Council Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, Scotland, United Kingdom; 2Hubrecht Laboratory-Koninklijke Nederlandse Akademie van Wetenschappen (KNAW), 3584 CT Utrecht, The Netherlands; 3Institute of Biomedical and Life Sciences, Division of Molecular Genetics, University of Glasgow, Anderson College, Glasgow G11 6NU, Scotland, United Kingdom The nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs harboring premature termination codons (PTCs). Seven genes (smg-1–7, for suppressor with morphological effect on genitalia) that are essential for NMD were originally identified in the nematode Caenorhabditis elegans, and orthologs of these genes have been found in several species. Whereas in humans NMD is linked to splicing, PTC definition occurs independently of exon boundaries in Drosophila. Here, we have conducted an analysis of the cis-acting sequences and trans-acting factors that are required for NMD in C. elegans. We show that a PTC codon is defined independently of introns in C. elegans and, consequently, components of the exon junction complex (EJC) are dispensable for NMD. We also show a distance-dependent effect, whereby PTCs that are closer to the 3 end of the mRNA are less sensitive to NMD. We also provide evidence for the existence of previously unidentified components of the NMD pathway that, unlike known smg genes, are essential for viability in C. -
S T O W E R S R E P O
2COMPLEX PROBLEM STOWER GONNA CALL? WHO YA S RE S EARCH ADVI S REQUIRE HIGHLY REQUIRE HIGHLY S OR S JUMP WHEN ACTION INTO S PECIALIZED EXPERTI S E STOWERS REPORT News aNd iNsight from the stowers iNstitute for medical research fall 2013 8 12 15 18 STOWERS REPORT PubliShEd by ThE STowERS inSTiTuTE FoR MEdiCAl RESEARCh FAll 2013 98 1312 dEPARTMEnTS 15 1 IN PERSPEctivE Executive message 18 2 fEatURES 12 tHE EXCHANGE 15 iN A NUTSHELL Research news 18 SCIENTIFIC SCIONS Introducing the next 2 generation inSTiTuTE nEwS 24 tHE SPOTLIGHT Awards and honors 27 ON campUS News and events 2 WHO YA GONNA caLL? 32 BacKstaGE pass Stowers research advisors jump into action when complex Glass wash: problems require highly specialized expertise A look behind the scenes 6 8 avErtiNG CHAOS Searching for the evolutionary origins of cellular order 12 A DISCUSSION WITH PETER BAUMANN ConTRibuToRS: For the newly minted HHMI investigator, Gina Kirchweger Linda Flynn Editor Copy editor chromosome biology has many faces Kristin Kessler Miller Medical Art Assistant editor Scientific Illustration 15 HIT BY TWO HAMMERS Elise Lamar Mark McDonald Deficiencies in two genes synergize to halt the Alissa Poh Don Ipock Contributing writers Photography formation of the gut nervous system Juan Carlos Grover Kuhn & Wittenborn Web editor Design and production 18 CHENGQI LIN, PHD The thrill of the scientific chase Visit the Stowers Institute at www.stowers.org or find us on Facebook at facebook.com/StowersInstitute The Stowers Report is printed on recycled paper. The Stowers Report is published by the Science Communications Department at the Stowers Institute for Medical Research. -
Back Off, Man, I'm a Scientist!'' When Marine
Ocean & Coastal Management 115 (2015) 71e76 Contents lists available at ScienceDirect Ocean & Coastal Management journal homepage: www.elsevier.com/locate/ocecoaman “Back off, man, I'm a scientist!” When marine conservation science meets policy * Naomi A. Rose a, E.C.M. Parsons b, a Animal Welfare Institute, Washington DC, USA b Department of Environmental Science & Policy, George Mason University, Fairfax, VA, USA article info abstract Article history: There is often a basic tension at the boundary between science and policy e the former seeks unbiased, Received 4 January 2015 objective descriptions of reality, while the latter must incorporate various factors in its development, Received in revised form including values, ideologies, economics, biases, and emotions. Problems may arise if, and when, marine 24 April 2015 scientists who enter the policy arena fail to understand these differing priorities, and we describe some Accepted 27 April 2015 common pitfalls. Various strategies are presented for marine conservation scientists to consider in order to avoid or minimize misunderstandings, especially with the media. Conflict of interest issues and public perception of bias are also addressed, as is misuse of research results and whether scientists have an Keywords: Marine conservation obligation to correct misrepresentation of their research. Finally, we consider how marine scientists Policy should address the inherent uncertainty in their results when those results are used to develop policy, Advocacy including the importance of incorporating the Precautionary Principle when making science-based Advice policy. Policy engagement © 2015 Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http:// Precautionary principle creativecommons.org/licenses/by-nc-nd/4.0/). -
Philip Zegerman
© 2015. Published by The Company of Biologists Ltd | Journal of Cell Science (2015) 128, 3361-3362 doi:10.1242/jcs.178145 CELL SCIENTISTS TO WATCH Cell scientist to watch – Philip Zegerman Philip Zegerman earned his undergraduate degree from the University of Cambridge, where he later also pursued a PhD in the lab of Tony Kouzarides at the Gurdon Institute. For his postdoctoral work, he switched fields from chromatin modifications to DNA replication, and joined John Diffley’s lab at Cancer Research UK, at Clare Hall in London. In 2009, Philip moved back to Cambridge to start his own group at the Gurdon Institute. He is an EMBO Young Investigator, and his lab is interested in how the initiation of DNA replication is regulated. What first motivated you to become a scientist? I have strong memories of doing experiments at school, which I think greatly influenced me. I remember one experiment very clearly, when I was probably about nine or ten. We went on a field trip and trapped and counted mice in a field. Doing experiments was really lots of fun and I was good at it. I originally thought I was going be an entomologist studying beetles because I loved insects, but when I went to university I started studying medical sciences and ended up in biochemistry and molecular biology. Your current research focuses on the regulation of DNA replication initiation. What are the particular questions your group is pursuing at the moment? It’s vitally important for all cells to make a perfect copy of the genome once and only once in every cell cycle. -
Gurdon Institute 2006 PROSPECTUS / ANNUAL REPORT 2005
The Wellcome Trust and Cancer Research UK Gurdon Institute 2006 PROSPECTUS / ANNUAL REPORT 2005 Gurdon I N S T I T U T E PROSPECTUS 2006 ANNUAL REPORT 2005 http://www.gurdon.cam.ac.uk THE GURDON INSTITUTE 1 CONTENTS THE INSTITUTE IN 2005 CHAIRMAN’S INTRODUCTION........................................................3 HISTORICAL BACKGROUND..............................................................4 CENTRAL SUPPORT SERVICES...........................................................5 FUNDING...........................................................................................................5 RESEARCH GROUPS........................................................................6 MEMBERS OF THE INSTITUTE..............................................42 CATEGORIES OF APPOINTMENT..................................................42 POSTGRADUATE OPPORTUNITIES.............................................42 SENIOR GROUP LEADERS..................................................................42 GROUP LEADERS......................................................................................48 SUPPORT STAFF..........................................................................................53 INSTITUTE PUBLICATIONS....................................................55 OTHER INFORMATION STAFF AFFILIATIONS................................................................................62 HONOURS AND AWARDS................................................................63 EDITORIAL BOARDS OF JOURNALS...........................................63