Norah Boyce Science Lectures Archives (In Academic Year Order – Most Recent First)
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
A DATA-ORIENTED NETWORK ARCHITECTURE Doctoral Dissertation
TKK Dissertations 140 Espoo 2008 A DATA-ORIENTED NETWORK ARCHITECTURE Doctoral Dissertation Teemu Koponen Helsinki University of Technology Faculty of Information and Natural Sciences Department of Computer Science and Engineering TKK Dissertations 140 Espoo 2008 A DATA-ORIENTED NETWORK ARCHITECTURE Doctoral Dissertation Teemu Koponen Dissertation for the degree of Doctor of Science in Technology to be presented with due permission of the Faculty of Information and Natural Sciences for public examination and debate in Auditorium T1 at Helsinki University of Technology (Espoo, Finland) on the 2nd of October, 2008, at 12 noon. Helsinki University of Technology Faculty of Information and Natural Sciences Department of Computer Science and Engineering Teknillinen korkeakoulu Informaatio- ja luonnontieteiden tiedekunta Tietotekniikan laitos Distribution: Helsinki University of Technology Faculty of Information and Natural Sciences Department of Computer Science and Engineering P.O. Box 5400 FI - 02015 TKK FINLAND URL: http://cse.tkk.fi/ Tel. +358-9-4511 © 2008 Teemu Koponen ISBN 978-951-22-9559-3 ISBN 978-951-22-9560-9 (PDF) ISSN 1795-2239 ISSN 1795-4584 (PDF) URL: http://lib.tkk.fi/Diss/2008/isbn9789512295609/ TKK-DISS-2510 Picaset Oy Helsinki 2008 AB ABSTRACT OF DOCTORAL DISSERTATION HELSINKI UNIVERSITY OF TECHNOLOGY P. O. BOX 1000, FI-02015 TKK http://www.tkk.fi Author Teemu Koponen Name of the dissertation A Data-Oriented Network Architecture Manuscript submitted 09.06.2008 Manuscript revised 12.09.2008 Date of the defence 02.10.2008 Monograph X Article dissertation (summary + original articles) Faculty Information and Natural Sciences Department Computer Science and Engineering Field of research Networking Opponent(s) Professor Jon Crowcroft Supervisor Professor Antti Ylä-Jääski Instructor(s) Dr. -
Communications of the Acm
COMMUNICATIONS CACM.ACM.ORG OF THEACM 11/2014 VOL.57 NO.11 Scene Understanding by Labeling Pixels Evolution of the Product Manager The Data on Diversity On Facebook, Most Ties Are Weak Keeping Online Reviews Honest Association for Computing Machinery tvx-full-page.pdf-newest.pdf 1 11/10/2013 12:03 3-5 JUNE, 2015 BRUSSELS, BELGIUM Course and Workshop C proposals by M 15 November 2014 Y CM Paper Submissions by MY 12 January 2015 CY CMY K Work in Progress, Demos, DC, & Industrial Submissions by 2 March 2015 Welcoming Submissions on Content Production Systems & Infrastructures Devices & Interaction Techniques Experience Design & Evaluation Media Studies Data Science & Recommendations Business Models & Marketing Innovative Concepts & Media Art TVX2015.COM [email protected] ACM Books M MORGAN& CLAYPOOL &C PUBLISHERS Publish your next book in the ACM Digital Library ACM Books is a new series of advanced level books for the computer science community, published by ACM in collaboration with Morgan & Claypool Publishers. I’m pleased that ACM Books is directed by a volunteer organization headed by a dynamic, informed, energetic, visionary Editor-in-Chief (Tamer Özsu), working closely with a forward-looking publisher (Morgan and Claypool). —Richard Snodgrass, University of Arizona books.acm.org ACM Books ◆ will include books from across the entire spectrum of computer science subject matter and will appeal to computing practitioners, researchers, educators, and students. ◆ will publish graduate level texts; research monographs/overviews of established and emerging fields; practitioner-level professional books; and books devoted to the history and social impact of computing. ◆ will be quickly and attractively published as ebooks and print volumes at affordable prices, and widely distributed in both print and digital formats through booksellers and to libraries and individual ACM members via the ACM Digital Library platform. -
Pooled CRISPR-Activation Screening Coupled with Single-Cell RNA-Seq in Mouse Embryonic Stem Cells
ll OPEN ACCESS Protocol Pooled CRISPR-activation screening coupled with single-cell RNA-seq in mouse embryonic stem cells Celia Alda-Catalinas, Melanie A. Eckersley-Maslin, Wolf Reik celia.x.aldacatalinas@gsk. com (C.A.-C.) [email protected]. uk (W.R.) Highlights Protocol for CRISPRa screens with single- cell readout to interrogate gene function Detailed description of CRISPRa screening procedures in mouse embryonic stem cells Detailed steps on how to construct derived single-cell sgRNA amplicon libraries CRISPR/Cas9 screens are a powerful approach to identify key regulators of biological processes. By combining pooled CRISPR/Cas9 screening with a single-cell RNA-sequencing readout, individual perturbations can be assessed in parallel both comprehensively and at scale. Importantly, this allows gene function and regulation to be interrogated at a cellular level in an unbiased manner. Here, we present a protocol to perform pooled CRISPR-activation screens in mouse embryonic stem cells using 103 Genomics scRNA-seq as a readout. Alda-Catalinas et al., STAR Protocols 2, 100426 June 18, 2021 ª 2021 The Authors. https://doi.org/10.1016/ j.xpro.2021.100426 ll OPEN ACCESS Protocol Pooled CRISPR-activation screening coupled with single-cell RNA-seq in mouse embryonic stem cells Celia Alda-Catalinas,1,4,7,* Melanie A. Eckersley-Maslin,1,5,6 and Wolf Reik1,2,3,8,* 1Epigenetics Programme, Babraham Institute, Cambridge CB22 3AT, UK 2Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK 3Centre for Trophoblast Research, University of -
President's Message
Winter Issue 2013–2014 SOT News President’s Message I’m starting this President’s message with a quiz!!! It’s just one question, but it’s important that everyone knows the answer. The question is: What do prenatal programming and toxicity, perfluorinalkyl acids ,and human relevance of hemangiosarcomas in rodents have in common? [the answer appears at the end of this message]. While you ponder the answer to that question, I want to reflect on events of this fall and focus on several activities of the Society during recent times of uncertainty. The shutdown of the US government had some effect on nearly all of us. Important meetings, study sections, and day-to- day professional discussion and dialog were all furloughed during this time. However, the most significant impact was on our members who are government employees, and we can only hope that these matters are completely behind us. Unfortunately, there were significant deadlines for SOT matters scheduled during this time, particularly for abstract submissions and award President nominations. Lois D. Lehman- McKeeman I want to specifically acknowledge the work of the Scientific Program and Awards Committees for showing remarkable flexibility in modifying deadlines to accommodate member needs. As a quick review, the Awards committee moved deadlines for nominations to the last possible minute—giving them only about 1 week to review all nominations prior to meeting to select award winners. The prestigious Society awards are central to celebrating member accomplishments, and the work of this committee, against their own time limitations, underscores their commitment to this important activity. -
The Oxford – Cambridge Arc Home of the New Innovation Economy
Economic Vision: The Oxford – Cambridge Arc Home of the New Innovation Economy April 2019 Contents 1 Introduction 3 2 The Economic Vision 8 3 The New Innovation Economy: Sectors 11 4 The Innovation & Growth Network 24 5 Achieving Ambitions 29 6 Conclusion: Critical Mass 35 | Introduction 1 Introduction 1.1 This vision’s purpose The purpose of the Economic Vision is to explain the Oxford - Cambridge Arc’s unified proposition as a globally leading innovation and growth catalyst. The Arc offers access to each of the critical ingredients for business and innovation-led growth. This collective offer represents a powerful and coherent expression of the region’s current assets and future potential. This Economic Vision for the Arc sets out an ambition and series of proposals designed to unlock the economic potential of the region and deliver transformative growth for the UK between now and 2050. It provides a vision for how the Arc can better connect its unique and world-leading assets to become truly globally competitive in frontier markets, both for business investment and for top talent. With a bolder brand and stronger international presence the Arc can continue to lead the whole of the UK to the forefront of global innovation excellence in the coming years and decades. 3 | Introduction This Economic Vision is built upon the foundation of This Economic Vision has been developed in the four local industrial strategies which currently partnership with the three LEPs and the Combined demarcate the Arc’s geographic area. These have Authority, who have been given a mandate by Central been prepared by the Oxfordshire (OxLEP), South Government to drive forwards the Economic Vision for East Midlands (SEMLEP) and Buckinghamshire the Arc: Thames Valley (BTVLEP) Local Enterprise Partnerships, as well as the Cambridgeshire & Peterborough Mayoral Combined Authority (CPCA). -
Society for Developmental Biology 64Th Annual Meeting
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Elsevier - Publisher Connector Developmental Biology 283 (2005) 537 – 574 www.elsevier.com/locate/ydbio Society for Developmental Biology 64th Annual Meeting Hyatt Regency, San Francisco, CA July 27–August 1, 2005 Organizing Committee: Judith Kimble (Chair, SDB President), Kathy Barton, Minx Fuller, Nipam Patel, Didier Stainier, Xin Sun, Bill Wood Local Organizers: Didier Stainier, Ida Chow Numbers in italics are program abstract numbers and names in bold are speakers. Poster assignments are listed at the end of the meeting program. Program Wednesday, July 27 9 am–5 pm Satellite Symposia (not organized by SDB) Segmentation Seacliff AB Co-organizers: Kenro Kusumi and Olivier Pourquie´ Molecular Biology of Plant Development Seacliff CD Organizer: Kathy Barton 12–7 pm Meeting Registration Grand Foyer Poster Session I and Exhibits Set-up Pacific Concourse See poster assignments at the end of the program 7–9 pm President’s Symposium Grand Ballroom Fundamental Problems of Developmental Biology Chair: Judith Kimble, University of Wisconsin-Madison and HHMI, Madison, WI 7:00 The soma-germline dichotomy. G. Seydoux. Johns Hopkins University, Baltimore, MD 1 7:40 MicroRNAs and their regulatory roles in plants and animals. D.P. Bartel. MIT and Whitehead Institute for Biomedical Research, Cambridge, MA 8:20 The genetics and genomics of evolving new traits in vertebrates. D. Kingsley. Stanford University and HHMI, Stanford, CA 9–11 pm Opening Reception in Honor of Eric Olson, Pacific Concourse Developmental Biology Editor-in-Chief, for invaluable service to the community Poster Session I and Exhibits Pacific Concourse See poster assignments at the end of the program YDBIO-02007; No. -
Gurdon Institute 20122011 PROSPECTUS / ANNUAL REPORT 20112010
The Wellcome Trust/Cancer Research UK Gurdon Institute 20122011 PROSPECTUS / ANNUAL REPORT 20112010 Gurdon I N S T I T U T E PROSPECTUS 2012 ANNUAL REPORT 2011 http://www.gurdon.cam.ac.uk CONTENTS THE INSTITUTE IN 2011 INTRODUCTION........................................................................................................................................3 HISTORICAL BACKGROUND..........................................................................................................4 CENTRAL SUPPORT SERVICES....................................................................................................5 FUNDING.........................................................................................................................................................5 RETREAT............................................................................................................................................................5 RESEARCH GROUPS.........................................................................................................6 MEMBERS OF THE INSTITUTE................................................................................44 CATEGORIES OF APPOINTMENT..............................................................................44 POSTGRADUATE OPPORTUNITIES..........................................................................44 SENIOR GROUP LEADERS.............................................................................................44 GROUP LEADERS.......................................................................................................................48 -
NORTHWESTERN UNIVERSITY Adopting a Gateway Centric View
NORTHWESTERN UNIVERSITY Adopting a Gateway Centric View for Cellular Network Content Delivery A DISSERTATION SUBMITTED TO THE GRADUATE SCHOOL IN PARTIAL FULFILLMENT OF THE REQUIREMENTS for the degree DOCTOR OF PHILOSOPHY Field of Computer Science By John Paul Rula EVANSTON, ILLINOIS June 2017 2 c Copyright by John Paul Rula 2017 All Rights Reserved 3 Committee Fabi´anBustamante (Chair), Northwestern University Aleksandar Kuzmanovic, Northwestern University Peter Dinda, Northwestern University Jon Crowcroft, University of Cambridge 4 ABSTRACT Adopting a Gateway Centric View for Cellular Network Content Delivery John Paul Rula Mobile traffic is expected to grow tenfold by 2019, topping 24 exabytes of monthly traffic and accounting for nearly half of all Internet traffic. This growth is driven by the increasing number of smart phones and tablets, and the data demands of high bandwidth services enabled by next-generation cellular networks such as LTE/5G. As in the wired Internet, network usage is dominated by content consumption, with the vast majority served through content delivery networks (CDNs). CDNs host and replicate popular content across thousands of servers worldwide, directing users to \nearby" servers. This replica selection is a key determinant of client performance, yet replica selection for cellular clients has previously been overlooked, due to high radio latency, inconsistent throughput, and a limited number of ingress locations which dominated end-to-end latency. NGCNs and their improved performance place a renewed emphasis on replica selection policies for cellular clients. We find that the performance of existing replica selection systems in cellular networks is hindered by their opacity, the dynamic assignment of clients to infrastructure components, the emergence of centralized DNS within cellular networks, and the growth of public DNS in global mobile operators. -
3 Is Not a Crowd, It's an Anecdote
3 is Not a Crowd, It’s an Anecdote Jon Crowcroft Marconi Professor of Communications Systems, Computer Laboratory University of Cambridge Cambridge, UK [email protected] Abstract has been crowd-sourced from the Internet, we should all be Crowd-sourcing measurements from the Internet, for the extremely aware of this non-trivial risk. In some areas of Internet, and by the Internet, is naturally popular due to the studies (e.g. censorship, hacktivism,cybercrime), the risk cost scaling that this approach offers. It appears to offer a of such re-identification to some members of our crowds low barrier to entry to new researchers, when compared with may be extremely high. We are all social scientists, now. the difficulties in obtaining data about operational networks ACM CCS Concepts: C.2, Networks from their owners. Keywords: Internet Measurement, Crowdsourcing, Privacy In this talk I will outline some precautions that should be taken by researchers, including: Sample Bias – Ground truth must be established about your sample. The very fact that you are using people on the internet prepared (assuming you have informed consent – you do, don’t you?) to be part of an experiment, means you have selection bias. Establish what it is by old fashioned means. Subject Privacy – You may get more buy-in from more users, and in more ways, if you can offer assurances about maintaining their privacy: o “No, this app won’t (unlike 70% of smart phone apps) leak lots of your Personal Data”, o How you achieve this, best practice with sandboxes and cryptography and security processes, o AAA applied to your logging databases, BIO o Long term fate, care and curation. -
Minutes of the Proceedings
MINUTES OF THE PROCEEDINGS at the Thirty‐sixth Meeting of the COUNCIL of the IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE The Thirty‐sixth Meeting of the Council was held in the Council Room, 170 Queen’s Gate, South Kensington Campus, Imperial College London, at 10:00 a.m. on Friday, 16th May 2014, when there were present: The Baroness Manningham‐Buller (Chair), Professor A. Anandalingam, Mr. C. Brinsmead, Dame Ruth Carnall, Mrs. P. Couttie, Professor M.J. Dallman, Mr. P. Dilley, Mr. D. Goldsmith, Professor N. Gooderham, Professor Dame Julia Higgins, Professor D.P.A. Kelleher, Ms. J.R. Lomax, Professor J. Magee, Mr. J. Newsum, Mr. S. Newton, Ms. K. Owen, Mr. M. Sanderson, Professor J Stirling, the President & Rector and the Clerk to the Court and Council. Apologies Mr. I. Conn. MINUTES Council – 7th February 2014 1. The Minutes of the thirty‐fifth Meeting of the Council, held on Friday, 7th February 2014, were taken as read, confirmed and signed. CHAIR’S REPORT 2. The Chair advised members that, following his appointment as Chair of the Chelsea and Westminster Hospital NHS Foundation Trust, Sir Thomas Hughes‐Hallett had resigned as a co‐opted member of the Council on 11 February. PRESIDENT & RECTOR’S REPORT 3. The President & Rector reported that this year’s Imperial Festival, held on 9th and 10th May, had received many visitors at the South Kensington campus to enjoy the various demonstrations, talks 1 Council 16th May 2014 and other activities on offer. What had started as a relatively modest pilot project in 2012 to explore how Imperial College London might share its research with more people had now evolved into a large‐scale and prominent annual fixture in the College’s calendar. -
Medical Research Council Annual Report and Accounts 2006/07 HC 93
06/07 Annual Report and Accounts © Crown Copyright 2006 The text in this document (excluding any Royal Arms and departmental logos) may be reproduced free of charge in any format or medium providing that it is reproduced accurately and not used in a misleading context. The material must be acknowledged as Crown copyright and the title of the document specified. Any queries relating to the copyright in this document should be addressed to The Licensing Division, HMSO, St Clements House, 2-16 Colegate, Norwich, NR3 1BQ. Fax: 01603 723000 or e-mail: licensing@cabinet-office.x.gsi.gov.uk 2 MRC Annual Report and Accounts 2006/07 Medical Research Council Annual Report and Accounts 2006/07 Presented to Parliament by the Secretary of State, and by the Comptroller and Auditor General in pursuance of Schedule I, Sections 2(2) and 3(3) of the Science and Technology Act 1965. Sir John Chisholm Chairman Professor Sir Leszek Borysiewicz Deputy Chairman and Chief Executive Ordered by and printed on London: The Stationery Office 6 February 2008 Price: £18.55 HC 93 The Medical Research Council The MRC RCUK The Medical Research Council (MRC) was set up in 1913 to administer Research Councils UK (RCUK) is a partnership of the seven (formerly public funds for medical research. It was incorporated under its eight) UK Research Councils – public bodies funded mainly by the UK present title by Royal Charter in 1920. A supplemental charter was Government via OSI. granted in 1993 describing the MRC’s new mission following the 1993 government white paper on science and technology. -
Privacy Engineering for Social Networks
UCAM-CL-TR-825 Technical Report ISSN 1476-2986 Number 825 Computer Laboratory Privacy engineering for social networks Jonathan Anderson December 2012 15 JJ Thomson Avenue Cambridge CB3 0FD United Kingdom phone +44 1223 763500 http://www.cl.cam.ac.uk/ c 2012 Jonathan Anderson This technical report is based on a dissertation submitted July 2012 by the author for the degree of Doctor of Philosophy to the University of Cambridge, Trinity College. Technical reports published by the University of Cambridge Computer Laboratory are freely available via the Internet: http://www.cl.cam.ac.uk/techreports/ ISSN 1476-2986 Privacy engineering for social networks Jonathan Anderson In this dissertation, I enumerate several privacy problems in online social net- works (OSNs) and describe a system called Footlights that addresses them. Foot- lights is a platform for distributed social applications that allows users to control the sharing of private information. It is designed to compete with the performance of today’s centralised OSNs, but it does not trust centralised infrastructure to en- force security properties. Based on several socio-technical scenarios, I extract concrete technical problems to be solved and show how the existing research literature does not solve them. Addressing these problems fully would fundamentally change users’ interactions with OSNs, providing real control over online sharing. I also demonstrate that today’s OSNs do not provide this control: both user data and the social graph are vulnerable to practical privacy attacks. Footlights’ storage substrate provides private, scalable, sharable storage using untrusted servers. Under realistic assumptions, the direct cost of operating this storage system is less than one US dollar per user-year.