Emergency Department Triage of Traumatic Head Injury Using Brain
ORIGINAL CONTRIBUTION Emergency Department Triage of Traumatic Head Injury Using a Brain Electrical Activity Biomarker: A Multisite Prospective Observational Validation Trial Daniel Hanley, MD, Leslie S. Prichep, PhD, Jeffrey Bazarian, MD, J. Stephen Huff, MD, Rosanne Naunheim, MD, John Garrett, MD, Elizabeth B. Jones, MD, David W. Wright, MD, John O’Neill, MD, Neeraj Badjatia, MD, Dheeraj Gandhi, MD, Kenneth C. Curley, MD, Richard Chiacchierini, PhD, Brian O’Neil, MD, and Dallas C. Hack, MD ABSTRACT Objectives: A brain electrical activity biomarker for identifying traumatic brain injury (TBI) in emergency department (ED) patients presenting with high Glasgow Coma Scale (GCS) after sustaining a head injury has shown promise for objective, rapid triage. The main objective of this study was to prospectively evaluate the From the Brain Injury Outcomes, The Johns Hopkins Medical Institutions (DH), Baltimore, MD; the Department of Psychiatry, New York University School of Medicine (LSP), New York, NY; BrainScope Company, Inc. (LSP), Bethesda, MD; the University of Rochester Medical Center (JB), Rochester, NY; the University of Virginia Health System (JSH), Charlottesville, VA; the Washington University Barnes Jewish Medical Center (RN), St. Louis, MO; the Baylor University Medical Center (JG), Dallas, TX; the University of Texas Memorial Hermann Hospital (EJ), Houston, TX; the Emory University School of Medicine and Grady Memorial Hospital (DW), Atlanta, GA; the Allegheny General Hospital (JO), Pittsburgh, PA; the R. Adams Cowley Shock Trauma Center (NB), Baltimore, MD; the Department of Radiology, University of Maryland (DG), Baltimore, MD; Iatrikos Research and Development Strategies, LLC (KCC), Tampa, FL; the Department of Surgery, Uniformed Services University of the Health Sciences (KCC), Bethesda, MD; R.
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