KCNB2 Antibody Cat. No.: 60-604

KCNB2 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Bovine

This KCNB2 antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 138-166 amino acids from the N-terminal region of human KCNB2.

TESTED APPLICATIONS: WB

APPLICATIONS: For WB starting dilution is: 1:1000

PREDICTED MOLECULAR 103 kDa WEIGHT:

Properties

This antibody is purified through a A column, followed by peptide affinity PURIFICATION: purification.

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

September 26, 2021 1 https://www.prosci-inc.com/kcnb2-antibody-60-604.html CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: KCNB2

Potassium voltage-gated channel subfamily B member 2, Voltage-gated potassium ALTERNATE NAMES: channel subunit Kv22, KCNB2

ACCESSION NO.: Q92953

PROTEIN GI NO.: 24418855

GENE ID: 9312

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. BACKGROUND: Four sequence-related - , shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel. The gene is expressed in gastrointestinal smooth muscle cells.

REFERENCES: 1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

2) Cirulli, E.T., et al. Eur. J. Hum. Genet. 18(7):815-820(2010)

3) Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)

4) Nyholt, D.R., et al. Hum. Mol. Genet. 17(21):3318-3331(2008)

ANTIBODIES FOR RESEARCH USE ONLY.

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