KCNB2 Antibody Cat. No.: 60-604 KCNB2 Antibody Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Bovine This KCNB2 antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 138-166 amino acids from the N-terminal region of human KCNB2. TESTED APPLICATIONS: WB APPLICATIONS: For WB starting dilution is: 1:1000 PREDICTED MOLECULAR 103 kDa WEIGHT: Properties This antibody is purified through a protein A column, followed by peptide affinity PURIFICATION: purification. CLONALITY: Polyclonal ISOTYPE: Rabbit Ig September 26, 2021 1 https://www.prosci-inc.com/kcnb2-antibody-60-604.html CONJUGATE: Unconjugated PHYSICAL STATE: Liquid BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide. CONCENTRATION: batch dependent Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. Additional Info OFFICIAL SYMBOL: KCNB2 Potassium voltage-gated channel subfamily B member 2, Voltage-gated potassium ALTERNATE NAMES: channel subunit Kv22, KCNB2 ACCESSION NO.: Q92953 PROTEIN GI NO.: 24418855 GENE ID: 9312 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. BACKGROUND: Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel. The gene is expressed in gastrointestinal smooth muscle cells. REFERENCES: 1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : 2) Cirulli, E.T., et al. Eur. J. Hum. Genet. 18(7):815-820(2010) 3) Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009) 4) Nyholt, D.R., et al. Hum. Mol. Genet. 17(21):3318-3331(2008) ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 26, 2021 2 https://www.prosci-inc.com/kcnb2-antibody-60-604.html.