DiaMed AG Diagnostics and Medical Products - 1785 Cressier Welcome Dinner Monday: 20th September, at 7.30 p.m. Meeting place: Murtenhof Restaurant,

Beginning of the course Tuesday: 21st September, at 9.00 a.m.

End of the course Banquet Thursday: 23rd September, at 7.30 p.m.

End of the course Friday: 24th September, at 2 p.m.

BISLAND Michael - Haemostasis – An Overview - Haemostasis – The Opposition / A Balanced View - Haemostasis – The Investigations - The Twilight of Anticoagulants / Point of Care Testing - Malaria Recognition

BROMILOW Imelda - From Myths to Molecules - Direct Antiglobulin Testing - Fetal and Neonatal Blood Transfusion - Quality Assurance in Transfusion Science - Case Studies and Interactive Session

OLSSON Martin - ABO – A Century of Transfusion Science - Remaining Mysteries of the P System and the GLOB Collection - Genomic Blood Group Typing in Clinical Transfusion Medicine - Some Functional Aspects of Blood Group Molecules - Modification of the Red Cell Membrane: Towards a Universal Blood Supply?

POOLE Joyce - How New Blood Group Antigens are Discovered and Defined - A Case of High Rh and Low (Kell) - The D Antigen and its Importance in the Donor, Recipient and Obstetric Populations - Problem Solving in Antibody Identification - Transfusing the Difficult Patient

Contact persons:

Imelda M. Bromilow/Suzanne Garcia phone number : ++41 26 674 51 11 fax number : ++41 26 674 56 45 e-mail addresses : [email protected] + [email protected] TUESDAY 21st September 2004

09:00 – 09:15 Introduction

09:15 – 10:15 From Myths to Molecules I. Bromilow

10:15 – 10:45 COFFEE BREAK

10:45 – 11:45 ABO – A Century of Transfusion Science M. Olsson

11:45 – 12:45 How New Blood Group Antigens are Discovered and Defined – A Case of High Rh and Low (Kell) J. Poole

13.00 – 14.00 LUNCH

14:00 – 14:30 Remaining Mysteries of the P System and the GLOB Collection M. Olssson

14:30 – 15:30 Direct Antiglobulin Testing I. Bromilow

15:30 – 16:00 COFFEE BREAK

16:00 – 17:00 Haemostasis – An Overview M. Bisland

TRANSFUSION SCIENCE COURSES DiaMed SA, CH-Cressier 3 WEDNESDAY 22nd September 2004

09:00 – 10:00 Fetal and Neonatal Blood Transfusion I. Bromilow

10:00 – 11:00 The D Antigen and its Importance in the Donor, Recipient and Obstetric Populations J. Poole

11:00 – 11:30 COFFEE BREAK

11:30 – 12:30 Genomic Blood Group Typing in Clinical Transfusion Medicine M. Olsson

12:30 – 13:30 LUNCH

13:30 – 14:30 Quality Assurance in Transfusion Science I. Bromilow

14:30 – 15:30 Haemostasis – The Opposition / A Balanced View M. Bisland

15:30 – 16:00 COFFEE BREAK

16:00- 17:00 Haemostasis – The Investigations M. Bisland

TRANSFUSION SCIENCE COURSES DiaMed SA, CH-Cressier 4 THURSDAY 23rd September 2004

09:00 – 10:00 Case Studies / Interactive Session I. Bromilow

10:00 – 11:00 Problem Solving in Antibody Identification J. Poole

11:00 – 11:30 COFFEE BREAK

11:30 – 12:30 Some Functional Aspects of Blood Group Molecules M. Olsson

12:30 – 13:30 LUNCH

13:30 – 14:30 The Twilight of Anticoagulants / Point of Care Testing M. Bisland

14:30 – 15:00 COFFEE BREAK

15:00- 16:00 Modification of the Red Cell Membrane : Towards a Universal Blood Supply? M. Olsson

OFFICIAL DINNER: 19:30 DRINKS 20:00 DINNER

TRANSFUSION SCIENCE COURSES DiaMed SA, CH-Cressier 5 FRIDAY 24th September 2004

09:00 – 10:00 Transfusing the Difficult Patient J. Poole

10:00 – 11:00 Malaria Recognition M. Bisland

11:00 – 11:30 COFFEE BREAK

11:30 – 12:00 Open Discussion

M. Bisland I. Bromilow J. Poole

12:00 – 12:30 Errors in the Transfusion Chain (NBS Video)

12:30 – 13:30 Tour of the company

13:30 LUNCH

TRANSFUSION SCIENCE COURSES DiaMed SA, CH-Cressier 6 . . . . .

INFO

AIRLINES / AIRPORTS

The Intercontinental Airports of Zurich, Geneva and Basel can be reached from various convenient gateways with scheduled services to Switzerland.

♦ Zurich and Geneva airports are fully integrated into the Swiss railroad network with an integrated railway station. Trains to the city run every 10 to 20 minutes. The ride takes approx. 10 minutes. Hourly intercity and direct trains leave right from the airport station and will connect you to many cities and towns.

♦ In Basel, a bus service links the airport with the downtown area. The bus stops right outside the main railway station. The buses leave every 30 minutes and the ride takes 15 to 20 minutes.

Distance between ♦ A Crossair taxi service connects the airport with Murten/Morat and… the downtown railway station in . The schedule is adjusted to the airline departures and arrivals. The ride takes approx. 20 minutes. Zürich 148 km

Geneva 136 km

Basel 125 km S C H E D U L E Crossair Taxi

Bern 28 km Monday - Saturday 05.15 - 08.15 Monday - Friday 09.00 - 12.30

Fribourg 17 km Monday – Friday 15.00 - 22.30

Sunday 15.00 - 22.30

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Murten/Morat SWISS FEDERAL RAILWAY Hotels STATIONS

Swiss Federal Railway Stations will accept the following credit cards: American Express, Diners Club, Eurocard/Mastercard and Visa.

Switzerland Travel Centre accepts Eurocard/Mastercard, Visa and American Express credit cards.

How to reach Murten/Morat from Geneva airport: this is an example of an itinerary

Geneva-Airport 16:21 train n° : IC 735 platform : s. *comments Genève 16:27 17:04 17:50

(No change procedures)

*comments : No responsibility accepted for platform details; please see notices at each station.

At Fribourg train station, alight and take the Fribourg/Morat train:

Fribourg 18:33 train n° : REG 4657 platform : 5 18:36 -Village 18:39 Pensier 18:43 18:46 Cressier FR 18:51 Münchenwiler 18:55 Murten/Morat 18:58

(No change procedures)

And for others connections, you will find at this website all train timetables - for

Switzerland: www.rail.ch

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BUSINESS/BANKING HOURS ♦ Business hours are weekdays 8 a.m. to 12 noon and 2 p.m. to 5 p.m., closed on weekends.

♦ Banks are usually open Monday to Friday from 8:30 a.m. to 4:30 p.m. Once a week they extend their hours. Banks are closed Saturdays, Sundays and on public holidays.

♦ Post offices in large cities are open Monday through Friday from 8:30 a.m. to 12 noon and from 1:30 p.m. to 6:00 p.m.; Saturday 7:30 to 11 a.m.

Please check locally.

MONEY & COSTS Currency: Swiss franc (CHF)

MEALS CHF US $ ♦ Budget 20 15 13 ♦ Mid-range 30-40 22-30 20-27 ♦ Top end 50-… 37-… 33-…

All major travellers’ cheques and credit cards are accepted. Commission is not charged for changing cash or cheques, but shop around for the best rates (hotels usually have the worst rates). Tipping is rarely necessary as hotels, restaurants and bars are required by law to include a 15% service charge. Even taxi fares normally have a service charge included.

Time: GMT/UTC plus one hour Electricity: 220 volts, 50Hz Weights & measures: Metric

CLIMATE Nov / Dec / Jan / Feb 0-5°C 30-36°F March / April 5-15°C 36-56°F May / June 18-22°C 62-70°F July / August 22-30°C 70-86°F Sept / Oct 15-20°C 56-66°F ......

HOTEL You should travel to Murten/Morat where hotel accommodation has been made.

As soon as you arrive at the hotel you will receive an envelope containing all information regarding the course, daily transport schedule from hotel to DiaMed AG (at Cressier), welcome dinner, etc.

WELCOME DINNER The Welcome Dinner will be held at the Murtenhof Restaurant, in Murten/Morat, on Monday evening, 20th September, at 7:30 p.m.

COURSE The course will begin on Tuesday morning, 21st September, at 9:00 a.m.

TRANSPORT Our driver will pick you up at the hotel, Tuesday morning and every morning at the hotel (8:30 a.m. approx.), and bring you to DiaMed AG where the course will be held.

Please be ready each morning to avoid delays to the course and inconvenience to other participants.

You will be taken back to the hotel when the course is finished (every afternoon – 5 p.m.)

DEPARTURE DAY You should take your luggage with you to DiaMed on Friday morning. Our driver will pick you up at the company, after the course and lunch time, and will take you to the nearest train station.

Transport back to the hotels will be organised after the lunch if you are departing from Switzerland during the weekend.

......

DiaMed AG will pay charges for:

• hotel room – only for the duration of the course (Monday to Friday inclusive) • lunches: from Tuesday to Friday • coffee breaks: from Tuesday to Friday • welcome dinner: Monday evening • end of course dinner: Thursday evening • course materials • daily transport - hotel to DiaMed and return

DiaMed will not pay charges for: - evening meals (Tuesday, Wednesday, Friday and/or supplementary days) - telephone charges - minibar - laundry - and all other personal charges

PLEASE NOTE:

1. It is not possible for us to arrange accommodation for longer stays, nor to find and book hotels for such additional days. If hotels are required, for example near to the airport, then please organise this independently: www.swisshotels.ch

2. Please inform in advance if your arrival/departure details change. Rooms reserved but not used must be paid for.

3. We do not have time to undertake return flight confirmation. A list of useful numbers will be supplied, however, so that participants requiring tickets to be confirmed may do so themselves.

4. Regrettably, we cannot organise tours or supply tourist information. Please contact Tourist Office at Murten/Morat at phone n°026 6715112 or visit them at this address: Französische Kirchgasse n°6 or check at websites: www.murtentourismus.ch, www.myswitzerland.com or www.pays-de-fribourg.ch

5. Participants departing from Switzerland after the last day of the course cannot be provided with DiaMed transport. . . . DIAMED AG . 1785 Cressier-sur-Morat . Switzerland Phone n°: 026 674 51 11 Fax n°: 026 674 53 10

USEFUL LINKS

TOURISM ƒ www.switzerlandtourism.ch ƒ www.swiss-towns.ch ƒ www.myswitzerland.com ƒ www.pays-de-fribourg.ch ƒ www.fribourgtourism.ch ƒ www.murtentourismus.ch

HOTELS ƒ www.swisshotels.ch ƒ www.murtenhof.ch ƒ www.hotel-bad-.ch ƒ www.hotel-schiff.ch ƒ www.hotel-seepark.ch ƒ www.hotel-enge.ch ƒ www.weisses-kreuz.ch ƒ www.auparc-hotel.ch ƒ www.goldentulip.ch

SWISS FEDERAL RAILWAYS ƒ www.rail.ch

CURRENCY ƒ www.oanda.com

AIRPORTS ƒ www.uniqueairport.com Zürich Airport ƒ www.gva.ch Geneva Airport ƒ www.euroairport.com Basel Airport

HOTELS

MURTENHOF HOTEL Rathausgasse 3 3280 MURTEN/MORAT

Phone n°: ++41 26 672 90 30 Fax n°: ++41 26 672 90 39 Website : www.murtenhof.ch 026 6729030

KRONE HOTEL Rathausgasse 5 3280 MURTEN/MORAT

Phone n°: ++41 26 670 52 52 Fax n°: ++41 26 670 36 10 Website : /

BAD MUNTELIER HOTEL Hauptstrasse 5 3286 MUNTELIER (Murten/Morat)

Phone n°: ++41 26 670 88 10 Fax n°: ++41 26 670 88 11 Website : www.hotel-bad-muntelier-ch

SCHIFF AM SEE HOTEL b. Dampfschiffstation 3280 MURTEN/MORAT

Phone n°: ++41 26 670 27 01 Fax n°: ++41 26 670 35 31 Website: www.hotel-schiff.ch

SEEPARK HOTEL Muntelierstrasse 25 3286 MUNTELIER (Murten/Morat)

Phone n°: ++41 26 672 66 66 Fax n°: ++41 26 672 66 77 Website : www.hotel-seepark.ch

HOTELS

ENGE HOTEL Bernstrasse 7 3280 MURTEN/MORAT

Phone n°: ++41 26 670 41 36 Fax n°: ++41 26 670 45 59 Website: www.hotel-enge.ch

WEISSES KREUZ HOTEL Rathausgasse 31 3280 MURTEN/MORAT

Phone n°: ++41 26 670 26 41 Fax n°: ++41 26 670 28 66 Website: www.weisses-kreuz.ch