Sodium Cyanate Manufaturer… TIRUPATI CYANATE

Total Page:16

File Type:pdf, Size:1020Kb

Sodium Cyanate Manufaturer… TIRUPATI CYANATE Sodium Cyanate Manufaturer… TIRUPATI CYANATE www.tirupaticyanate.com ABOUT US___________________________________________________ Tirupati cyanate is leading manufacturer and provider of sodium cyanate. Our excellent customer service and high quality of Sodium cyanate in bulk makes us unique in the market. Tirupati cyanate is exporters of sodium cyanate in volumes to supply to the demands of its customers in local market and around the world. We undertake custom synthesis and manufacture sodium cyanate as per demand and under secrecy agreement. Please enquire and contact us for further information on sodium cynate mentioning your specific requirements. Sodium Cyanate Specification CAS No 917-61-3 Cyanic Acid, Sodium Salt, Natriumcyanat 9, Synonym Cianato de sodio, Cyanate de sodium Molecular Weight 65.01 Empirical Formula NaOCn Sodium Cyanate Physical property Purity Minimum 90% Melting Point 550°C Density 1.893 g/cm3 Solubility 10 gm at 25ºC Physical Appearance Free Flowing White Powder Soda Ash Content Less Than 5% Cyanate (-OCN) Content Between 59.5 % to 61.3 % Loss on Drying (At 110ºC)Max Maximum 0.05 Packaging Information HDPE Bags inside liner of 25kgs, 50 Kgs. Capacity Company Tirupati cyanate, chhatral GIDC industrial estate, Dist. Gandhinagar, Gujarat, India Sodium cyanate Application Sodium Cyanate is mainly used as herbicides & in heat treatment of metal. As herbicides it is used mostly to wipeout weeds in lawns and onion crops. It also used as a fertilizer because sodium cyanate contains high volume of nitrogen. Copyright © TIRUPATI CYANATE 2005-2013 Sodium Cyanate Manufaturer… TIRUPATI CYANATE www.tirupaticyanate.com Sodium cyanate is also used in the synthesis of pesticides and dyes intermediates. Because it reactios with organic compounds are formation of urea derivatives are obtained by reaction with amines. It is also used in the syntheses of pesticides, detergents and plastic additives. Please enquire for further technical information and your specific requirement in small and bulk quantities of Sodium Cynates. GRATIS SAMPLES ARE AVAILABLE. For free sample log on to http://www.tirupaticyanate.com/about_us.htm Contact us__________________________________________________________ For your requirements of Sodium Cynates contact us at- TIRUPATI CYANATES Office address: Tirupati Cyanate 27, Ambica Society Opp. Vidhyanagar school, Near Usmanpura under bridge, Usmanpura, Ahmedabad, Gujarat, India- 380013 Contact Person: Mr. Rushabh Patel +91-9033009826 Tel no : Email : [email protected] Website : www.tirupaticyanate.com Why Us? Some of our distinguishing attributes those gives us and extra edge over other market leaders are: • Complete testing of the products • Timely delivery • Sound industry knowledge • Safe and hygienic products • Relations with numerous reputed manufacturers and vendors • Capacious stocking ability to meet the bulk requirements • Wide spread network of distributors • Gujarat Pollution Control Board (GPCB) approved Copyright © TIRUPATI CYANATE 2005-2013 .
Recommended publications
  • 1 Abietic Acid R Abrasive Silica for Polishing DR Acenaphthene M (LC
    1 abietic acid R abrasive silica for polishing DR acenaphthene M (LC) acenaphthene quinone R acenaphthylene R acetal (see 1,1-diethoxyethane) acetaldehyde M (FC) acetaldehyde-d (CH3CDO) R acetaldehyde dimethyl acetal CH acetaldoxime R acetamide M (LC) acetamidinium chloride R acetamidoacrylic acid 2- NB acetamidobenzaldehyde p- R acetamidobenzenesulfonyl chloride 4- R acetamidodeoxythioglucopyranose triacetate 2- -2- -1- -β-D- 3,4,6- AB acetamidomethylthiazole 2- -4- PB acetanilide M (LC) acetazolamide R acetdimethylamide see dimethylacetamide, N,N- acethydrazide R acetic acid M (solv) acetic anhydride M (FC) acetmethylamide see methylacetamide, N- acetoacetamide R acetoacetanilide R acetoacetic acid, lithium salt R acetobromoglucose -α-D- NB acetohydroxamic acid R acetoin R acetol (hydroxyacetone) R acetonaphthalide (α)R acetone M (solv) acetone ,A.R. M (solv) acetone-d6 RM acetone cyanohydrin R acetonedicarboxylic acid ,dimethyl ester R acetonedicarboxylic acid -1,3- R acetone dimethyl acetal see dimethoxypropane 2,2- acetonitrile M (solv) acetonitrile-d3 RM acetonylacetone see hexanedione 2,5- acetonylbenzylhydroxycoumarin (3-(α- -4- R acetophenone M (LC) acetophenone oxime R acetophenone trimethylsilyl enol ether see phenyltrimethylsilyl... acetoxyacetone (oxopropyl acetate 2-) R acetoxybenzoic acid 4- DS acetoxynaphthoic acid 6- -2- R 2 acetylacetaldehyde dimethylacetal R acetylacetone (pentanedione -2,4-) M (C) acetylbenzonitrile p- R acetylbiphenyl 4- see phenylacetophenone, p- acetyl bromide M (FC) acetylbromothiophene 2- -5-
    [Show full text]
  • WO 2014/185925 Al 20 November 2014 (20.11.2014) P O P C T
    (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2014/185925 Al 20 November 2014 (20.11.2014) P O P C T (51) International Patent Classification: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BOW 53/28 (2006.01) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (21) International Application Number: HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, PCT/US20 13/04 1503 KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, (22) International Filing Date: ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, 17 May 2013 (17.05.2013) NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, (25) Filing Language: English TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, (26) Publication Language: English ZM, ZW. (71) Applicant: EMPIRE TECHNOLOGY DEVELOP¬ (84) Designated States (unless otherwise indicated, for every MENT LLC [US/US]; 271 1 Centerville Road, Suite 400, kind of regional protection available): ARIPO (BW, GH, Wilmington, Delaware 19808 (US). GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, (72) Inventors: PEPPOU, George Charles; 4 Armen Way, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, Hornsby Heights, New South Wales 2077 (AU).
    [Show full text]
  • Investigating Cell Type Specific Mechanisms Contributing to Acute Oral Toxicity
    Prieto et al.: Investigating cell type specific mechanisms contributing to acute oral toxicity Supplementary Data1 Tab. S1: Overview of collected information on specific target organ/system and general cytotoxicity for chemicals correctly assigned to the CLP acute oral toxicity category by the 3T3 NRU cytotoxicity assay General Nervous Cardiovascular GI Chemical Liver Lung Blood Kidney cytotoxicity system system system (±)-Propranolol hydrochloride x ax (4-ammonio-m-tolyl)ethyl(2- x x hydroxyethyl)ammonium sulphate 1,2,4-Trichlorobenzene x x 1,2-Dichlorobenzene x x 2,4,6- x x Tris(dimethylaminomethyl)phenol 2,4-Dichlorophenoxyacetic acid x x x 5,5-Diphenylhydantoin x x 5-Fluorouracil x x x x Acetophenone x Acetylsalicylic acid x x x x x x Acrolein x x Acrylamide x x x Ammonium chloride x ax ax Atropine sulfate monohydrate x x Benzaldehyde x x Cadmium (III) chloride x x x x x Caffeine x x x Chloroform x x ax x x x x Chloroquine bis(phosphate) x x Chlorpromazine x x x Codeine x x x x Colchicine x x x x Copper sulphate x x x Cupric sulfate pentahydrate x x Cyclosporin A x x x x Diazepam x Diphenhydramine hydrochloride x x Disopyramide x x Ethyl chloroacetate x x Ferrous sulphate x x x Glufosinate-ammonium x Glutethimide x ax x Hexachlorophene x x Lithium Carbonate x x x Lithium sulphate x x x Malathion x x Maleic acid x x Meprobamate x x Orphenadrine hydrochloride x x x x p-Benzoquinone x x x Phenol x x x x x Procainamide hydrochloride x x x Quinidine sulfate dehydrate x x x Resorcinol x x Rifampicin x x doi:10.14573/altex.1805181s2 ALTEX ##(#), SUPPLEMENTARY DATA 1 General Nervous Cardiovascular GI Chemical Liver Lung Blood Kidney cytotoxicity system system system Sodium Cyanate x x sodium oxalate x x x Sodium valproate x bx x x Thioridazine hydrochloride x x Valproic acid x x x x x GI: Gastrointestinal; CLP: Classification, labelling and packaging; NRU: Neutral Red Uptake; a Indirect effect: b chronic effect Tab.
    [Show full text]
  • United States Patent Office Patented Dec
    3,631,000 United States Patent Office Patented Dec. 28, 1971 2 SUMMARY OF THE INVENTION 3,631,000 SOCYANURATE-CONTAINING POLYSOCYA We have found that superior isocyanurate-containing NATES AND METHOD OF PREPARATION polyisocyanates are inexpensively prepared by the two Perry A. Argabright and Brian L. Philips, Littleton, Colo., step process of: (1) chloroalkylating a mono-substituted and Vernon J. Sinkey, South St. Paul, Minn., assignors benzene compound, and (2) reacting the polychloro to Marathon Oil Company, Findlay, Ohio alkylated benzene-substituted compounds with a metal No Drawing. Filed June 4, 1969, Ser. No. 830,541 cyanate in the conjoint presence of a bromide or iodide Int. C. C08g 22/18, 22/44 of an alkali metal or an alkaline earth metal, and in the U.S. C. 260-77.5 NC 1. Claims presence of an aprotic solvent, herein defined. The mole IO ratio of metal cyanate to the chloride in the polychloro alkylated benzene-substituted compound is from about ABSTRACT OF THE DESCLOSURE 0.8 to about 1.5 to produce the polyisocyanates. These Improved organic polyisocyanates are prepared by re polyisocyanate compositions are starting materials for acting chlorinated benzene-substituted compounds, espe Various polymeric systems, e.g. a rigid polyurethane foam cially chloromethylated aromatics, with metal cyanates in 5 produced by conventional polymerization or copolymeri the presence of a metal iodide or bromide and in the zation with an appropriate monomer (e.g. a polyester or presence of a dipolar aprotic solvent where the mole ratio polyether based polyol). Particularly preferred products of cyanate in the metal cyanate to chlorine in the chlo are polyurethane and polyurea foams, coatings, elasto rine-containing benzene-substituted compound is from mers and adhesives.
    [Show full text]
  • Chemical Names and CAS Numbers Final
    Chemical Abstract Chemical Formula Chemical Name Service (CAS) Number C3H8O 1‐propanol C4H7BrO2 2‐bromobutyric acid 80‐58‐0 GeH3COOH 2‐germaacetic acid C4H10 2‐methylpropane 75‐28‐5 C3H8O 2‐propanol 67‐63‐0 C6H10O3 4‐acetylbutyric acid 448671 C4H7BrO2 4‐bromobutyric acid 2623‐87‐2 CH3CHO acetaldehyde CH3CONH2 acetamide C8H9NO2 acetaminophen 103‐90‐2 − C2H3O2 acetate ion − CH3COO acetate ion C2H4O2 acetic acid 64‐19‐7 CH3COOH acetic acid (CH3)2CO acetone CH3COCl acetyl chloride C2H2 acetylene 74‐86‐2 HCCH acetylene C9H8O4 acetylsalicylic acid 50‐78‐2 H2C(CH)CN acrylonitrile C3H7NO2 Ala C3H7NO2 alanine 56‐41‐7 NaAlSi3O3 albite AlSb aluminium antimonide 25152‐52‐7 AlAs aluminium arsenide 22831‐42‐1 AlBO2 aluminium borate 61279‐70‐7 AlBO aluminium boron oxide 12041‐48‐4 AlBr3 aluminium bromide 7727‐15‐3 AlBr3•6H2O aluminium bromide hexahydrate 2149397 AlCl4Cs aluminium caesium tetrachloride 17992‐03‐9 AlCl3 aluminium chloride (anhydrous) 7446‐70‐0 AlCl3•6H2O aluminium chloride hexahydrate 7784‐13‐6 AlClO aluminium chloride oxide 13596‐11‐7 AlB2 aluminium diboride 12041‐50‐8 AlF2 aluminium difluoride 13569‐23‐8 AlF2O aluminium difluoride oxide 38344‐66‐0 AlB12 aluminium dodecaboride 12041‐54‐2 Al2F6 aluminium fluoride 17949‐86‐9 AlF3 aluminium fluoride 7784‐18‐1 Al(CHO2)3 aluminium formate 7360‐53‐4 1 of 75 Chemical Abstract Chemical Formula Chemical Name Service (CAS) Number Al(OH)3 aluminium hydroxide 21645‐51‐2 Al2I6 aluminium iodide 18898‐35‐6 AlI3 aluminium iodide 7784‐23‐8 AlBr aluminium monobromide 22359‐97‐3 AlCl aluminium monochloride
    [Show full text]
  • (12) United States Patent (10) Patent No.: US 8,877,934 B2 Berger Et Al
    US008877934B2 (12) United States Patent (10) Patent No.: US 8,877,934 B2 Berger et al. (45) Date of Patent: Nov. 4, 2014 (54) N-HETEROARYL COMPOUNDS (52) U.S. Cl. CPC ............ C07D 213/89 (2013.01); C07D401/04 (75) Inventors: Michael Berger, Schwabenheim (DE); (2013.01); C07D 213/74 (2013.01); C07D Christopher Kern, Schwabenheim 239/47 (2013.01); C07D 239/42 (2013.01); (DE); Marko Eck, Schwabenheim (DE): C07D 413/04 (2013.01); C07D491/048 Jörg Schröder, Schwabenheim (DE) (2013.01); C07D 471/04 (2013.01); C07D 215/46 (2013.01) (73) Assignee: Intervet Inc., Summit, NJ (US) USPC ........................................ 546/309; 514/235.8 (58) Field of Classification Search (*) Notice: Subject to any disclaimer, the term of this None patent is extended or adjusted under 35 See application file for complete search history. U.S.C. 154(b) by 0 days. (56) References Cited (21) Appl. No.: 13/876,724 FOREIGN PATENT DOCUMENTS (22) PCT Filed: Sep. 28, 2011 CN 1.01284.812 A 10, 2008 EP 1900 772 A2 3, 2008 (86). PCT No.: WO 2004/03.5591 A1 4/2004 WO 2008/028689 A1 3, 2008 S371 (c)(1), WO 2008/028691 A1 3, 2008 (2), (4) Date: Mar. 28, 2013 OTHER PUBLICATIONS (87) PCT Pub. No.: WO2012/041873 Silva, A., Mini-Reviews in Medicinal Chemistry, 2005, vol. 5, pp. 893-1014.* PCT Pub. Date: Apr. 5, 2012 Jabbar et al., “Anthelmintic resistance: the sate of play revisited'. Life Sciences, 2006, pp. 2413-2431, vol. 79. (65) Prior Publication Data McKellar et al., “Veterinary anthelmintics: old and new”, Trends in US 2013/O196993 A1 Aug.
    [Show full text]
  • Rpt POL-TOXIC AIR POLLUTANTS 98 BY
    SWCAA TOXIC AIR POLLUTANTS '98 by CAS ASIL TAP SQER CAS No HAP POLLUTANT NAME HAP CAT 24hr ug/m3 Ann ug/m3 Class lbs/yr lbs/hr none17 BN 1750 0.20 ALUMINUM compounds none0.00023 AY None None ARSENIC compounds (E649418) ARSENIC COMPOUNDS none0.12 AY 20 None BENZENE, TOLUENE, ETHYLBENZENE, XYLENES BENZENE none0.12 AY 20 None BTEX BENZENE none0.000083 AY None None CHROMIUM (VI) compounds CHROMIUM COMPOUN none0.000083 AY None None CHROMIUM compounds (E649962) CHROMIUM COMPOUN none0.0016 AY 0.5 None COKE OVEN COMPOUNDS (E649830) - CAA 112B COKE OVEN EMISSIONS none3.3 BN 175 0.02 COPPER compounds none0.67 BN 175 0.02 COTTON DUST (raw) none17 BY 1,750 0.20 CYANIDE compounds CYANIDE COMPOUNDS none33 BN 5,250 0.60 FIBROUS GLASS DUST none33 BY 5,250 0.60 FINE MINERAL FIBERS FINE MINERAL FIBERS none8.3 BN 175 0.20 FLUORIDES, as F, containing fluoride, NOS none0.00000003 AY None None FURANS, NITRO- DIOXINS/FURANS none5900 BY 43,748 5.0 HEXANE, other isomers none3.3 BN 175 0.02 IRON SALTS, soluble as Fe none00 AN None None ISOPROPYL OILS none0.5 AY None None LEAD compounds (E650002) LEAD COMPOUNDS none0.4 BY 175 0.02 MANGANESE compounds (E650010) MANGANESE COMPOU none0.33 BY 175 0.02 MERCURY compounds (E650028) MERCURY COMPOUND none33 BY 5,250 0.60 MINERAL FIBERS ((fine), incl glass, glass wool, rock wool, slag w FINE MINERAL FIBERS none0.0021 AY 0.5 None NICKEL 59 (NY059280) NICKEL COMPOUNDS none0.0021 AY 0.5 None NICKEL compounds (E650036) NICKEL COMPOUNDS none0.00000003 AY None None NITROFURANS (nitrofurans furazolidone) DIOXINS/FURANS none0.0013
    [Show full text]
  • 1. Give the Correct Names for Each of the Compounds Listed Below. A
    1. Give the correct names for each of the compounds listed below. a) NaCl sodium chloride n) ZrS2 zirconium sulfide b) FrBr francium bromide o) AgI silver iodide c) KF potassium fluoride p) BaSe barium selenide d) RaS radium sulfide q) MgO magnesium oxide e) LiI lithium iodide r) LaBr3 lanthanum bromide f) Li3N lithium nitride s) Sr3N2 strontium nitride g) AlBr3 aluminum bromide t) Cd3As2 cadmium arsenide h) CdCl2 cadmium chloride u) Rb2Se rubidium selenide i) K2O potassium oxide v) Rb3N rubidium nitride j) InF3 indium fluoride w) BaF2 barium fluoride k) ZnO zinc oxide x) ZrTe2 zirconium telluride l) Y2O3 yttrium oxide y) Cs3P cesium phosphide m) CaTe calcium telluride z) Y2O3 yttrium oxide 2. Write the correct chemical formula for each of the following compounds. a) potassium bromide KBr n) potassium nitride K3N b) zinc bromide ZnBr2 o) aluminum bromide AlBr3 c) lithium iodide LiI p) zinc phosphide Zn3P2 d) scandium chloride ScCl3 q) magnesium sulfide MgS e) magnesium chloride MgCl2 r) hafnium chloride HfCl4 f) magnesium oxide MgO s) barium sulfide BaS g) hydrogen sulfide H2S t) tantalum oxide Ta2O5 h) gallium iodide GaI3 u) zirconium nitride Zr3N4 i) sodium oxide Na2O v) potassium selenide K2Se j) magnesium selenide MgSe w) germanium fluoride GeF4 k) calcium fluoride CaF2 x) francium phosphide Fr3P l) aluminum oxide Al2O3 y) zinc arsenide Zn3As2 m) beryllium chloride BeCl2 z) scandium telluride Sc2Te3 L. h. s. – Chemistry – Nomenclature – Answers – Page 1 3. Give the correct names for each of the compounds listed below. a) CaSO4 calcium
    [Show full text]
  • Kinetics and Mechanism of Alkaline Hydrolysis of Urea and Sodium
    Indian Journal of Chemistry Vol. 35A, December 1996, pp. 1116-1119 Kinetics and mechanism of alkaline formed during the hydrolysis of urea. Though the hydrolysis of urea and sodium cyanate mechanism had been given, neither rate determin- ing step had been defined nor rate expression had Zaheer Khan" been given. The alkaline hydrolysis of urea was Chemistry Department, Jamia Millia Islamia, not a simple first order reaction and required JamiaNagar, New Delhi 110 025, India much more kinetic studies. Therefore, the kinetics and of the reaction has been studied in alkaline medi- um with the aim to establish the consecutive na- MZ A Rafiquee, Kabir-ud-din, M Arif Niaz & A Aziz Khan ture as well as mechanism of two step hydrolysis Chemistry Department, AIigarh Muslim University, of urea. The rate constants of the consecutive AIigarh 202 002, India steps have been calculated using Swain equation". Received 20 March 1996; revised 20 June 1996 In support of the mechanism of ureolysis, basic The kinetics of hydrolysis of urea has been studied hydrolysis of cyante was also described in the in 0.5 to 3.0 mol dm - 3 sodium hydroxide solution at note. different temperatures. Urea hydrolysis follows an irreversible first order consecutive reaction path: Experimental Urea (BDH), sodium cyanate (Fluka) and sodi- 10bs 20bs um nitrate (E. Merck) were used as such. The • • urea k cyanate k NH3 + CO2 -NH3 stock solution of carbonate free sodium hydroxide (E. Merck) at about 17 mol dm "! was prepared The variation of k10bs with [alkali] is linear. at and diluted to the required concentrations using 3 [OH-]=5.0 to 1.5 mol dm- , thereafter a sharp in- doubly distilled water.
    [Show full text]
  • PRIZE LIST 2010 Edited by Viral
    PRICE LIST 2013 NILE CHEMICALS pH INDICATORS , BIOLOGICAL STAINS CATALYST FOOD COLOURS CHEMICALS (LAB & BULK) REAGENTS (LAB & BULK) LABO ATORY REAGENTS & FINE CHEMICALS PRODUCT PROFILE PURE, EXTRA PURE, PURIFIED We have pure , extra pure and purified products , available as per buyers requirements and specifications. GUARANTEED REAGENTS (GR) Our Guaranteed Reagents are used for analytical and research work, where high purity is essential. This is similar to grade marketed by other International company. HPLC GRADE This are high performance chemicals , used in liquid chromatography used frequently in biochemistry and analytical chemistry to separate, identify, and quantify compounds SPECTROSCOPY GRADE These are solvents of high optical purity for UV/Visible/IR/Fluorescence/NMR and Mass spectroscopy. BIOLOGICAL STAIN Our Ph Indicators are ready to use solutions for Microbiology, Histology, Hematology and Cytology and are at par with certified grade stains as per International norms. Address : 202,Matruchhay ,378 /80 Narshi Natha Street ,Masjid , Mumbai -400 009 INDIA Email : [email protected] Tel: 91 22 66313162 : Fax : 91 22 23454828 Web site www.nilechemicals.com NILE CHEMICALS EXPLOSIVES: Certain Substances reacts exothermically, generating gases, which may explode on heating, hence storage may be required in water or suitable solvent OXIDISING:Some Substance reacts with oxygen and may cause fire hazard TOXIC:Certain substance on contact with human body may cause acute or chronic damage HARMFUL:Certain substance on contact with human body may cause acute or chronic damage FLAMABLE:Chemicals , Solvents with a flash point below zero degree and boiling point of 35 deg c are termed as flammable items CORROSIVE:Substance which causes severe damage to living tissues IRRITANT:Substance which causes irritation on contact with skin etc DANGEROUS: substance which causes damages to ecosystem RADIOACTIVE:Substance which evolves radiation in the ecosystem NILE CHEMICALS PRICE LSIT 2013 CAT.NOS.
    [Show full text]
  • The Sickling Process in Relation to Clinical Manifestations
    J Clin Pathol: first published as 10.1136/jcp.s3-8.1.23 on 1 January 1974. Downloaded from J. clin. Path., 27, Suppl. (Roy. Coll. Path.), 8, 23-25 The sickling process in relation to clinical manifestations A. J. BELLINGHAM From the Department of Clinical Haematology, University College Hospital Medical School, London The knowledge of the detailed structure and function sites have not been defined but the polymeriza- of the haemoglobin molecule has led to a better tion is conformational-dependent as it only occurs understanding of the pathophysiology of the in the deoxy state which is evidenced by the standard clinical syndromes associated with abnormal haemo- test in vitro with metabisulphate which examines for globins. Not least of these is the commonest haemo- the sickling of cells as they are deoxygenated. globin variant seen in the UK, sickle haemoglobin Crystallographic and electron microscopic studies (Hb-S). Sickle cell disease is characterized by have shown that the tactoid formation is ordered painful crises and a chronic haemolytic state which and regular. The sickle molecules form long strands stem from the haemoglobin's tendency to polymerize which are themselves in bundles of six having a leading to distortion and rigidity of the red cell hexagonal cross section and also having a twist causing blocking of small capillaries and the red rather like the spinning of a piece of thread. The cells' premature destruction. twist is such that it takes a strand of 48 molecules to Haemoglobin consists of a tetramer of 2ca and do a complete turn (360°) which means the length 2f chains existing in two conformational states in required for this is approximately 3000 A (Finch, equilibrium with each other: these are known as Perutz, Bertles, and Dobler, 1973).
    [Show full text]
  • Saccharomyces Cerevisiae EZ-Accu Shottm
    General Catalog of Kanto Reagents, Chemicals & Biologicals + Oct. 2021 Saccharomyces cerevisiae EZ-Accu ShotTM store at 2℃-8℃ 49944-78 MB(0699A) ATCC9763 5test JPY46,000 Saccharomyces cerevisiae KWIK-STIKTM store at 2℃-8℃ 49843-14 MB(0534P) ATCC4098 2pack JPY13,500 49843-15 MB(0900P) ATCC9080 2pack JPY13,500 49823-87 MB(0699P) ATCC9763 2pack JPY13,500 49820-65 MB(01066P) ATCC18824 2pack JPY14,500 49825-87 MB(0736P) NCYC79 2pack JPY14,500 Saccharomyces cerevisiae KWIK-STIKTM Plus store at 2℃-8℃ 49842-47 MB(0699X) ATCC9763 5pack JPY45,000 Saccharomyces kudriavzevii KWIK-STIKTM store at 2℃-8℃ 49823-86 MB(0698P) ATCC2601 2pack JPY13,500 Saccharomyces kudriavzevii KWIK-STIKTM Plus store at 2℃-8℃ 49840-76 MB(0698X) ATCC2601 5pack JPY45,000 Salmonella bongori KWIK-STIKTM store at 2℃-8℃ 49843-52 MB(0595P) ATCC43975 2pack JPY16,500 General Catalog of Kanto Reagents, Chemicals & Biologicals + Oct. 2021 Salmonella enterica subsp.arizonae EZ-Accu ShotTM store at 2℃-8℃ 49946-13 MB(0901A) ATCC13314 5test JPY46,000 Salmonella enterica subsp.arizonae KWIK-STIKTM store at 2℃-8℃ 49823-91 MB(0901P) ATCC13314 2pack JPY13,500 Salmonella enterica subsp.diarizonae KWIK-STIKTM store at 2℃-8℃ 49820-33 MB(01054P) ATCC12325 2pack JPY14,500 49844-90 MB(01045P) ATCC29934 2pack JPY14,500 Salmonella enterica subsp.enterica serotype Abony EZ-CFUTM store at 2℃-8℃ 49840-79 MB(0890C) NCTC6017 10test JPY87,000 Salmonella enterica subsp.enterica serotype Abony EZ-CFUTM One Step store at 2℃-8℃ 49842-70 MB(0890Z) NCTC6017 10test JPY86,000 Salmonella enterica subsp.enterica serotype Abony KWIK-STIKTM store at 2℃-8℃ 49825-88 MB(0890P) NCTC6017 2pack JPY11,500 General Catalog of Kanto Reagents, Chemicals & Biologicals + Oct.
    [Show full text]