Tufts Medical Center

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Tufts Medical Center (Boston, MA) Tufts Medical Center originated in 1796 as the “Boston Dispensary” (upper left), created and supported by Boston’s leading citizens including patriots Paul Revere and Samuel Adams (upper right), and was New England’s first permanent medical facility and third in the U.S. Keeping faith with its mission, the Dispensary provided free healthcare for Boston’s poor. In 1894, the Floating Hospital for Children, New England’s first facility dedicated solely to pediatric medical care, was established to provide health care services to Boston’s poor children, exposing them to the therapeutic environment of sea air and sunshine as a boat in Boston Harbor (lower right). The Floating Hospital was also a leader in pediatric medical research and developed the first syn- thetic milk product for infants (still sold today as Similac). In 1929, the Dispensary affiliated with the Floating (and later with Pratt Diagnostic Clinic, built in 1931) to become the major teaching hospital of Tufts University School of Medicine. The current Medi- cal Center remains in the same downtown location as the Dispensary, still dedicated to compassionate, patient-centered care. Tufts-New England Medical Center, as it became known, was the home of numerous scientific advancements, including pivotal work in immunology, ushering in the modern transplantation era. The rich cardiovascular clinical and research heritage of what is now called Tufts Medical Center (lower left) includes seminal work in establishing the importance of diastolic function in human disease, early studies of balloon valvuloplasty and laser intervention, sudden death prevention in adults and children, the rela- tion between remodeling and outcomes in heart failure (HF), and contrast and 3D echocardiography. The Molecular Cardiology Research Institute has made numerous landmark discoveries, particularly related to the effects of estrogen and aldosterone on vascular biology. Tufts Medical Center’s prolific clinical and academic programs include advanced HF (begun in the early 1980s and now the largest ventricular assist and heart transplant program in New England), interventional HF and structural heart disease, cardiac electrophysiology, and hypertrophic cardiomyopathy (HCM), the latter with a national/international referral base and a newly-launched research institute to build a new paradigm of HCM prevention and treatment. Barry J. Maron, MD Tufts Medical Center

950 March 7, 2017 Circulation. 2017;135:939–950. DOI: 10.1161/CIRCULATIONAHA.115.016520