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Honors Biology Summer Packet 2014-2015 Ms.Chorman School email: [email protected] (contact me by email if you have any questions) – must have email contact form turned in

Contents of Summer Packet  Purpose  Welcome to IRHS Honors Biology  Teacher Introduction  Summer Assignments: o I. Summer Reading o II. Are viruses alive?

When is the Summer Packet Due? The Packet will be due the first day back to school and will count as your first quiz grade. Total Points = 50 (formative) Extra Credit = 5 pts if you email it to me at least 2 days before the first day of school Purpose  The purpose of this packet is to familiarize you with the material that will be covered in HONORS BIOLOGY this coming year, and to introduce an overlying theme of the Life Processes of Living Things Welcome Every student will need:  a pencil or pen (blue/black ink)  1 or 2 inch 3-ring binder notebook  Dividers (5)  Flash drive (will help with summer and marking period projects)  Ear buds that can fit into an iPad or computer audio outlet (they do not need to be expensive)

Optional: (homework pass)  hand soap, construction paper, tissues, paper towels STUDY GUIDE QUESTIONS for “” by

Type the answers to these questions onto a word document. 12font Times New Roman, single space

Please indicate the page number(s) where you find the answers for each question.

READING SECTION I: PAGES 1-94 PART I: “THE SHADOW OF MOUNT ELGON”

Something in the Forest

1. Where is Mount Elgon? Describe the surrounding environment.

2. How may Charles Monet have been exposed to a level 4 virus?

3. Describe the symptoms experienced by Charles Monet in the days following his visit to .

4. In what ways could the virus have been passed to other people from the time Monet left his house until he arrived at Nairobi hospital?

5. How did Dr. Musoke become infected?

6. Describe the results of Dr. Musoke’s exploratory surgery.

Diagnosis 7. Who is David Silverstein?

8. What virus was found in Dr. Musoke’s blood? Describe the virus and it’s origin.

9. What is a filovirus?

10. Which is the worst of the filovirus “sisters”? What is the kill rate in humans?

11. What is one general theory for the origin of AIDS?

12. What was the outcome for Dr. Musoke?

A Woman and A Soldier 13. Who is Nancy Jaax?

14. How did Nancy Jaax cut her hand? Why is this significant?

Project 15. What does USAMRIID stand for?

16. What kinds of precautions were necessary for Nancy Jaax to be able to work in 3 conditions? What problems did she face?

17. What is unique about Biosafety Level 4?

18. Describe the first known emergence of the Ebola virus. How did it get its name?

19. Who is Eugene Johnson?

20. How many different proteins make up an Ebola virus particle? What is known about them?

21. Describe the effects of the Ebola virus. How does it appear to be spread?

22. Describe the Biosafety Level staging area. Describe the suit required for work in Biosafety Level 4.

Total Immersion 23. Describe the symptoms exhibited by the monkeys that were infected with Ebola.

24. What happened to the Ebola infected monkeys? What became of the healthy monkeys? How?

READING SECTION II: PAGES 95-153

1. Describe Ebola Sudan.

2. Describe Ebola Zaire.

3. Describe how the disease was spread through the Yambuku hospital.

4. Describe the shape of the Ebola virus.

5. What is the C.D.C.?

6. Describe how the medical teams worked to prevent the further spread of the disease throughout Kinshasa.

7. How many other people caught the virus from Nurse Mayinga?

Cardinal 8. Who is Eugene Johnson?

9. Who is Peter Cardinal?

10. Explain why a virus may be more like a predator than a parasite.

11. How might Peter Cardinal have become infected?

Going Deep 12. Describe the expedition to Kitum Cave. What was the purpose of this trip?

13. What was the result of this expedition?

READING SECTION III PAGES 157-282 PART II: “THE MONKEY HOUSE” 1. What kinds of monkeys were kept at the Reston Monkey House?

2. How many monkeys out of the original shipment did Bill Volt count as dead within one month’s time?

3. Who is Dan Delgard?

4. Describe the deaths of the monkeys.

Into Level 3 5. Who is Peter Jahrling?

6. How did Delgard ship the results of the monkey autopsy to Jahrling?

Exposure 7. Who is Tom Geisbert?

Thanksgiving 8. What significant event occurred over the Thanksgiving holiday in the monkey house?

Medusa 9. What discovery did Geisbert make about the viruses infecting the monkeys?

The First Angel 10. Who is C.J. Peters?

11. What was the purpose of the conversation between Jahrling and Geisbert? (see page 206.)

12. What came of this conversation?

The Second Angel 13. Describe Jahrling's tests with the virus samples.

14. What were the results of these tests?

Chain of Command 15. What is meant by a “chain of command” in relation to biohazard work?

Garbage Bags 16. Who is Jarvis Purdy? What happened to him?

17. How were the dead monkey’s shipped to Fort Detrick?

Space Walk 18. What were the results of the monkey autopsy?

Shoot-Out 19. Who is Joe McCormick?

The Mission 20. What are the Three Priorities?

Reconnaissance 21. Describe the conditions of the monkey house upon the team entering the building.

READING SECTION IV: PAGES 285-371 PART III: “SMASHDOWN” Insertion 1. Describe the orange Racal suits that are designed for use with airborne biological agents.

2. Describe the decontamination process upon leaving the monkey building.

3. What was located right next door to the monkey house?

A Man Down 4. Who is Milton Frantig? What happened to him?

91-Tangos 5. How many monkeys occupied the building?

Inside 6. What happened to Rhonda Williams?

A Bad Day 7. What significant event occurred on Wednesday December 6?

8. What did the team do to the remaining monkey’s that were still alive?

Decon 9. Describe how the team attempted to “Decon” the monkey house.

The Most Dangerous Strain 10. Describe the Ebola strain.

11. How many humans died from Ebola Reston?

12. Why is the Reston virus so much like Ebola Zaire, when Reston supposedly comes from Asia?

READING SECTION V: PAGES 375-411 PART IV: “KITUM CAVE” 1. Describe the author’s journey to Kitum Cave? Why did he make this journey?

2. How did AIDS likely first appear?

3. Why have vaccines against HIV been unsuccessful?

4. What became of the Reston, Virginia monkey house?

5. What is the author's view on the emergence of these destructive viruses?

Part II: Are Viruses Alive? 1. Locate a reputable website (not wiki sites) that indicates at least 6, scientifically proven, characteristics of living things. Be sure to site this website on your paper. (just cut and past the URL)

2. Go to the following sites and read up on virus characteristics and Ebola. a. http://www.microbeworld.org/types-of-microbes/viruses b. http://www.cdc.gov/vhf/ebola/

3. On the same paper that you answered the Hot Zone questions, establish a separate section and answer the following question. To get full points it must be a minimum of 4 paragraphs in length, and your answer must be supported with information you have obtained from either the Hot Zone, Microbe World website (above), the CDC website (above), and your “characteristics of living things” website you located.

4. You must site where your supporting information comes from by putting the short hand listed below in parenthesis, behind the sentence containing support information from a website (the information which is not “your” words) Source Short Hand site a. Hot Zone by Richard Preston (Preston) b. http://www.microbeworld.org/types-of-microbes/viruses (MW) c. http://www.cdc.gov/vhf/ebola/ (CDC) d. Your chosen site for char. of life (Life)

Question: Are viruses living?

Scoring: (Formative)

Part I: The Hot Zone __5__ pts Type the answers to questions in complete sentences. 12 font Times New Roman, single space

__10__ pts Please indicate the page number(s) where you find the answers for each question.

__10__ pts Answer all questions

__10__ pts A large handful of questions will be checked for correctness (teachers choice)

Part II: Viruses Alive?

_2__ pts Site a reputable website for characteristics of living things (just cut and past the URL)

_1.5__ pts Minimum of 4 paragraphs

_2.5__ pts Writing style (proper grammar, answer is clear and easy to understand)

_9__ pts Well thought out answer that is supported by external sources and sources are sited properly.

Total Points = ___/ 50

Extra Credit = 5 pts if you email it to me at least 2 days before the first day of school

Note: Sharing of reading summaries is considered a violation of the IRHS Honor Code and will be dealt with according to the procedures designated in the student handbook. Natural 1. Nature Selection Biology 4. of Evolution Science

Evidence Drug Observation & Experimental Resistant Design Bacteria Inference Primate Evolution

2. Meiosis Biochemistry

Inheritance Digestion & Enzymes

Mitosis 3. Genetics Photosynthesis Molecules of Life

DNA