2019 RiboClub Program RNA: 20 Years of Discoveries In Association with the Gairdner Foundation September 22-27 - Hotel Chéribourg, Orford, Québec, Canada
Organizing Committee: Allan Jacobson, Robert Singer, Adrian Krainer, Françoise Stutz, Yukihide Tomari, Sandra Wolin, Nehalkumar Thakor (ARRTI co-organizer for western Canada) and the RiboClub.
Sunday, September 22, 2019 (Day1)
15:00 – 20:00 Registration / Coffee and cake
17:00 – 17:10 Welcome notes and Announcements Sherif Abou Elela RiboClub organizer and co-founder, Member of the Université de Sherbrooke RNA Group
17:15 – 17:45 Opening Lecture I: RNA Biology: Origins and Reflections Joan Steitz Sterling Professor of Molecular Biophysics and Biochemistry, Yale University First speakers of the RiboClub 1998
17:45 – 18:15 Opening Lecture II: RNA Biology: History of Discoveries Witold Filipowicz Professor of Biochemistry, Friedrich Miescher Institute for Biomedical Research
18:15 – 18:45 Special presentation by the recipient of the RiboClub 2009 life achievement award: Initiating the study of Initiation: Initiating translation initiation: a short history and perspective Nahum Sonenberg, Member of the RiboClub, Gilman Cheney Chair in Biochemistry, McGill University
18:45 – 19:45 Cocktail and social time
19:45 – 19:50 Introduction of members of the community and dignitaries Raymund Wellinger Master of ceremonies, Co-founder of the Université de Sherbrooke RNA group,
19:50 – 19:50 Welcome note Pierre Cossette President, Université de Sherbrooke
19:50 – 20:45 Networking Dinner
20:45 – 20:55 Student Recognition and Travel Awards Eric Masse RiboClub Member, Université de Sherbrooke.
20:45 – 20:50 RNA studies at the Université de Sherbrooke Nathalie Rivard Vice Dean Research, Graduate Studies and Innovation, Faculty of Medicine and Health Sciences, Université de Sherbrooke
20:50 – 21:00 RNA Biology in Canada and the Training of Future Professionals Hans-Joachim Wieden Director, Alberta RNA Research and Training Institute University of Lethbridge
21:00 – 23:30 Get Together
Monday, September 23, 2019 (Day2)
Public session: Introduction
9:00 – 9:10 Highlights of the RiboClub 2019 Sherif Abou Elela RiboClub organizer and co-founder, Member of the Université de Sherbrooke RNA Group
9:10 –9:15. Gairdner Foundation Supporting Excellence in RNA Biology Janet Rossant President and Scientific Director, Gairdner Foundation
Public session: The RiboClub and the Societal Impact of RNA Research Host: Michelle Scott, Member of the Université de Sherbrooke RNA group
9:15 – 9:25 Riboclub: Building an RNA Community to Trigger Discoveries Benoit Chabot Co-founder of the Université de Sherbrooke RNA group
9:25 –9:30 The RiboClub: A Training Playground for Future Researchers Jonathan Perreault Former students’ representative, 2017 Alumnus of the year, member of the RiboClub, Professor at INRS-Institute Armand-Frappier
9:30 –9:35 Role of Institutions in Supporting and Developing RNA Based Research Jean-Pierre Perreault Vice-President Research and Graduated Studies, co-founder of the Université de Sherbrooke RNA group
9:35 –9:40 Funding RNA Research to Improve Healthcare Michael Strong President, Canadian Institutes for Health Research (CIHR)
9:40 –9:45 The Outlook for Basic Research in Canada Mona Nemer Chief Science Advisor of the Government of Canada
9:45 - 10:00 Open Questions and Panel Discussion Moderators: Martin Simard, 2004 Alumnus of the year, Université Laval and Thomas Duchaine, 2012 Alumnus of the year, McGill University
Participants: Sherif Abou Elela, Benoit Chabot, Jean-Pierre Perreault, Janet Rossant, Michael Strong, Mona Nemer, Jonathan Perreault
10:00 – 10:30 Coffee break and social time
Public Session: RNA Based Discoveries and Impact Presenter: Stephen Rader RiboClub member, University of Northern British Columbia
10:30 –10:50 Re-Writing Genomes with CRISPR RNAs Erik Sontheimer The RNA Therapeutic Institute, University of Massachusetts Medical School, Founder of Intellia Therapeutics Inc. Developer of CRISPR-based therapy.
10:50 - 11:10 Genetic Nonsense: From Bench to Bedside and Back to the Bench Allan Jacobson Chair of the Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Professor of Pathology and Cell biology, Founder of Applied biotechnology Inc and Founder and Director of PTC Therapeutics Inc. Developer of Translarna as treatment for Duchenne Muscular Dystrophy
11:10 - 11:30 RNA Splicing: From Discovery to Treatment Adrian Krainer St. Giles Foundation Professor at Cold Spring Harbor Laboratory, Laureate of Life Sciences Breakthrough Prize 2019, Founder and Director of Stoke Therapeutics Inc., Inventor of Spinraza, the first approved drug for spinal muscular atrophy
11:30 –12:00 Panel Discussion and Questions Moderator: Katherine Borden Canada Research Chair, Professor of Pathology and Cell biology, Université de Montréal
Panel Participants: Adrian Krainer, Erik Sontheimer, Allan Jacobson
End of public session and departure of unregistered guests
Scientific Meeting
13:00 - 14:00 Lunch for registered guests
Session 1: RNA Silencing
Chair: Victor Ambros
14:00 - 14:15 Victor Ambros Introduction and history
14:15 - 14:30 Michael McManus
14:30 - 14:45 Yukihide Tomari
14:45 - 15:00 Lin He
15:00 - 15:15 Olivia Rissland
15:15 - 15:25 Selection from abstract
15:25 - 15:35 Selection from abstract
15:35 – 16:05 Questions and panel discussions Moderator: Muthiah Manoharan, Alnylam Pharmaceuticals
16:05 - 16:25 Coffee Break
Session 2: RNA editing, modification and transcriptomics
Session Chair: Brenda Bass
16:25 - 16:40 Brenda Bass Introduction and history
16:40 - 16:55 Tsutomu Suzuki
16:55 - 17:10 Wendy Gilbert
17:10 - 17:25 Pierre Close
17:25 - 17:40 Chuan He
17:40 - 17:50 Selection from abstract
17:50 – 18:00 Selection from abstract
18:00 – 18:30 Questions and panel discussion Moderator: Valerie A. De Crecy-Lagard
18:30 – 21:00 Dinner
21:00 – 22:00 Get Together
Tuesday September 24, 2019 (Day 3)
07:00 - 08:00 Breakfast
Session 3: Bacterial RNA
Chair: Susan Gottesman
08:00 - 08:15 Susan Gottesman Introduction and history
08:15 - 08:30 Jörg Vogel
08:30 - 08:45 Eric Masse
08:45 - 09:00 Lydia Contreras 09:00 - 09:15 Cynthia Sharma
09:15 - 09:25 Selection from abstract
09:25 - 09:35 Selection from abstract
09:35 - 10:05 Questions and panel discussion Moderator: Sarah Woodson
10:05 – 10:35 Coffee Break
Session 4A: Non-coding RNA
Chair: David Bartel
10:35 - 10:50 David Bartel Introduction and history
10:50 - 11:05 Wade Winkler
11:05 - 11:20 Sherif Abou Elela
11:20 - 11:35 Alena Shkumatava
11:35 - 11:50 Lingling Chen
11:50 - 12:00 Selection from abstract
12:00 - 12:10 Selection from abstract
12:10– 12:40 Questions and panel discussion Moderator: TBD
12:40 - 14:00 Mentor mentee Lunch
Session 4B: Non-coding RNA
Chair: Kathy Collins
14:00 - 14:15 Introduction and history Kathy Collins
14:15 - 14:30 Claus Azzalin
14:30 - 14:45 Jorgen Kjems
14:45 - 15:00 Howard Chang
15:00 - 15:15 Anton Petrov
15:15 - 15:25 Selection from abstract
15:25 - 15:35 Selection from abstract
15:35 – 16:05 Questions and panel discussion Moderator: Raymund Wellinger
16:05 – 16:35 Coffee break
Session 5: Ribosome structure and function
Chair: Joachim Frank
16:35 - 16:50 Introduction and history Joachim Frank
16:50 - 17:05 Marat Yusupov
17:05 - 17:20 Andrei Korostelev
17:20 - 17:35 Jamie Williamson
17:35 - 17:45 Selection from abstract
17:45 - 17:55 Selection from abstract
17:55 – 18:25 Questions and panel discussion Moderator: Gloria Culver
18:25 - 18:45 Students’ Poster Promotion Micro talks (2 minutes talks by students) Host: Daniel Lafontaine
18:45 - 19:45 Dinner
19:45 - 21:45 Poster Session I
21:45 - 23:00 Get Together
Wednesday September 25, 2019 (Day 4)
07:00 - 08:00 Breakfast
Session 6: Spliceosome structure and dynamics
Chair: Reinhardt Lührmann
08:00 - 08:15 Reinhardt Lührmann: Introduction and history
08:15 - 08:30 Dan Larson
08:30 - 08:45 Kiyoshi Nagai
08:45 - 09:00 Doug Black
09:00- 09:15 Manny Ares
09:15 - 09:25 Selection from abstract
09:25 - 09:35 Selection from abstract
09:35 - 10:05 Questions and panel discussions Moderator: Chris Trotta 10:05 - 10:35 Coffee Break
Session 7: RNA decay and surveillance
10:35 - 10:50 Introduction and history Allan Jacobson
10:50 - 11:05 Lori Passmore
11:05 - 11:20 Torben Heick Jensen
11:20 - 11:35 Lynne Maquat
11:35- 11:50 Jianjun Chen
11:50 - 12:00 Selection from abstract
12:00 - 12:10 Selection from abstract
12:10 - 12:40 Questions and panel discussion (applications and future) Moderator: Kristian Baker
12:40 – 12:55 Group photo
12:55 – 14:40 Lunch
14:40 – 16:40 Poster session II
16:40 – 19:00 Free afternoon
19:00 - 20:30 Dinner
20:30 - 20:40 The blue jacket awardees. Martin Bisaillon
20:40 - 20:50 Poster awards presentation by Michelle Scott
20:50 - 21:10 RNA biology: the early days Marvin Wickens Max Perutz Professor of Molecular Biology and Biochemistry, University of Wisconsin Introduction by Mark Schmitt, SUNY Upstate Medical University
21:30 - 23:00 Get together
Thursday September 26, 2019 (Day 5)
07:00 - 08:00 Breakfast
Session 8: RNA and Immunity
Session Chair: Sandra Wolin
8:00 - 8:15 Sandra Wolin Introduction and history
8:15 - 8:30 Daniel Stetson
8:30 - 8:45 Uttiya Basu
8:45 -9:00 Karla Kirkegaard
9:00 - 9:15 Selection from abstract
9:15 - 9:25 Selection from abstract
9:25 - 9:35 Selection from abstract
9:35 - 10:05 Questions and panel discussion Moderator: Jonathan Yingling,
10:05 - 10:35 Coffee Break
Session 9: Alternative splicing mechanisms and regulation
Chair: John Mattick
10:35 - 10:50 John Mattick: Introduction and history
10:50 - 11:05 Benoit Chabot
11:05 - 11:20 Ben Blencowe
11:20 - 11:35 Kristen Lynch
11:35 - 11:50 Karla Neugebauer
11:50 - 12:00 Selection from abstract
12:00 - 12:10 Selection from abstract
12:10 - 12:40 Questions and Panel discussion (applications and future) Moderator: TBD
12:40 - 14:40 Lunch
Session 10: RNA granules and droplets
Chair: Roy Parker
14:40 - 14:55 Roy Parker
14:55 - 15:10 Mark Ashe
15:10 - 15:25 Graciela L. Boccaccio
15:25 - 15:40 Ross Buchan
15:40 - 15:50 Selection from abstract
15:50 - 16:00 Selection from abstract
16:00 - 16:30 Questions and Panel discussion (applications and future) Moderator: Rachel Meyers
16:30 - 17:00 Coffee break
Session 11: RNA structure, evolution, aptamer and catalytic RNA
Chair: Larry Gold
17:00 - 17:15 Larry Gold
17:15 - 17:30 Jack Szostak
17:30 - 17:45 Adrian R. Ferré-D’Amare
17:45 - 18:00 Alan Lambowitz
18:00 - 18:15 David Mathews
18:15 - 18:45 Questions and panel discussion
Moderator: TBD
18:45 – 19:20 Students choice special presentation Andrew Fire
19:30 - 20:30 Closing Gala and Awards Ceremony Host: Francois Bachand, Director of the Université de Sherbrooke Center of RNA Biology, member of Université de Sherbrooke RNA group
20:30 - 20:35 The Dean’s Notes Dominque Dorion Dean, Faculty of Medicine and Health Sciences, Université de Sherbrooke
20:35 - 21:10 Special presentation of a lifetime of RNA biology Phillip Sharp Professor, Koch Institute for Integrative Cancer Research at MIT
Introduction by Andrew McMillan, Member of the RiboClub, University of Alberta
21:10 - 21:20 Presentation of the life achievement award Nahum Sonnenberg James McGill Professor of Biochemistry, McGill University and HHMI senior international research scholar,
21:20 - 21:25 Predicting the future, Closing Remarks Benoit Chabot, co-founder of Université de Sherbrooke RNA group
21:25 - 23:30 Entertainment and Music show Brendan Bell, Member of the Université de Sherbrooke RNA group
23:30 - Dance
Friday September 27, 2019 (Day 6)
07:00 - 09:00 Breakfast
Departure