<p><strong>2019 RiboClub Program </strong><br><strong>RNA: 20 Years of Discoveries </strong></p><p><strong>In Association with the Gairdner Foundation </strong></p><p><em>September 22-27 - &nbsp; Hotel Chéribourg, Orford, Québec, Canada </em><br><em>Organizing Committee: Allan Jacobson, Robert Singer, Adrian Krainer, Françoise Stutz, Yukihide Tomari, Sandra Wolin, Nehalkumar Thakor (ARRTI co-organizer for western </em><br><em>Canada) and the RiboClub. </em></p><p><strong>Sunday, September 22, 2019 (Day1) </strong></p><p>15:00 – 20:00 Registration / Coffee and cake 17:00 – 17:10 Welcome notes and Announcements <br>Sherif Abou Elela </p><p><em>RiboClub organizer and co-founder, Member of the &nbsp; Université de Sherbrooke RNA Group </em></p><p>17:15 – 17:45 Opening Lecture I: RNA Biology: Origins and Reflections <br>Joan Steitz Sterling Professor of Molecular Biophysics and Biochemistry, Yale University First speakers of the RiboClub 1998 </p><p>17:45 – 18:15 Opening Lecture II: RNA Biology: History of Discoveries <br>Witold Filipowicz </p><p><em>Professor of Biochemistry, Friedrich Miescher Institute for Biomedical Research </em></p><p>18:15 – 18:45 Special presentation by the recipient of the RiboClub 2009 life achievement award: Initiating the study of Initiation: Initiating translation initiation: a short history and perspective <em>Nahum Sonenberg, </em>Member of the RiboClub, Gilman Cheney Chair in Biochemistry, McGill University </p><p>18:45 – 19:45 Cocktail and social time 19:45 – 19:50 Introduction of members of the community and dignitaries <br>Raymund Wellinger </p><p>Master of ceremonies<em>, Co-founder of the Université de Sherbrooke RNA group, </em></p><p>19:50 – 19:50 Welcome note <br>Pierre Cossette President, Université de Sherbrooke <br>19:50 – 20:45 Networking Dinner 20:45 – 20:55 Student Recognition and Travel Awards <br>Eric Masse </p><p><em>RiboClub Member, Université de Sherbrooke. </em></p><p>20:45 – 20:50 RNA studies at the Université de Sherbrooke <br>Nathalie Rivard </p><p><em>Vice Dean Research, Graduate Studies and Innovation, Faculty of Medicine and Health Sciences, Université de Sherbrooke </em></p><p>20:50 – 21:00 RNA Biology in Canada and the Training of Future Professionals <br>Hans-Joachim Wieden </p><p><em>Director, Alberta RNA Research and Training Institute University of Lethbridge </em></p><p>21:00 – 23:30 Get Together </p><p><strong>Monday, September 23, 2019 (Day2) Public session: Introduction </strong>9:00 – 9:10&nbsp;<strong>Highlights of the RiboClub 2019 </strong></p><p>Sherif Abou Elela </p><p><em>RiboClub organizer and co-founder, Member of the &nbsp; Université de Sherbrooke RNA Group </em></p><p>9:10 –9:15.&nbsp;<strong>Gairdner Foundation Supporting Excellence in RNA Biology </strong></p><p>Janet Rossant </p><p><em>President and Scientific Director, Gairdner Foundation </em></p><p><strong>Public session: The RiboClub and the Societal Impact of RNA Research </strong></p><p>Host: Michelle Scott, <em>Member of the &nbsp; Université de Sherbrooke RNA group </em></p><p>9:15 – 9:25&nbsp;<strong>Riboclub: Building an RNA Community to Trigger Discoveries </strong></p><p>Benoit Chabot </p><p><em>Co-founder of the Université de Sherbrooke RNA group </em></p><p>9:25 –9:30&nbsp;<strong>The RiboClub: A Training Playground for Future Researchers </strong></p><p>Jonathan Perreault </p><p><em>Former students’ representative, 2017 Alumnus of the year, member of the RiboClub, Professor at INRS-Institute Armand-Frappier </em></p><p>9:30 –9:35&nbsp;<strong>Role of Institutions in Supporting and Developing RNA Based Research </strong></p><p>Jean-Pierre Perreault </p><p><em>Vice-President Research and Graduated Studies, co-founder of the Université de Sherbrooke RNA group </em></p><p>9:35 –9:40&nbsp;<strong>Funding RNA Research to Improve Healthcare </strong></p><p>Michael Strong </p><p><em>President, Canadian Institutes for Health Research (CIHR) </em></p><p>9:40 –9:45&nbsp;<strong>The Outlook for Basic Research in Canada </strong></p><p>Mona Nemer </p><p><em>Chief Science Advisor of the Government of Canada </em></p><p>9:45 - 10:00&nbsp;<strong>Open Questions and Panel Discussion </strong></p><p>Moderators: Martin Simard,&nbsp;2004 Alumnus of the year, Université Laval and Thomas Duchaine, 2012 Alumnus of the year, McGill University </p><p>Participants: Sherif Abou Elela, Benoit Chabot, Jean-Pierre Perreault, Janet Rossant, Michael Strong, Mona Nemer, Jonathan Perreault </p><p>10:00 – 10:30 Coffee break and social time </p><p><strong>Public Session: RNA Based Discoveries and Impact </strong></p><p>Presenter: Stephen Rader </p><p><em>RiboClub member, University of Northern British &nbsp; Columbia </em></p><p>10:30 –10:50 <strong>Re-Writing Genomes with CRISPR RNAs </strong></p><p>Erik Sontheimer </p><p><em>The RNA Therapeutic Institute, University of Massachusetts Medical School, Founder of Intellia Therapeutics Inc. Developer of CRISPR-based therapy. </em></p><p>10:50 - 11:10 <strong>Genetic Nonsense: From Bench to Bedside and Back to the Bench </strong></p><p>Allan Jacobson </p><p><em>Chair of the Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Professor of Pathology and Cell biology, Founder of Applied biotechnology Inc and Founder and Director of PTC Therapeutics Inc. Developer of Translarna as treatment for Duchenne Muscular Dystrophy </em></p><p>11:10 - 11:30 <strong>RNA Splicing: From Discovery to Treatment </strong></p><p>Adrian Krainer </p><p><em>St. Giles Foundation Professor at Cold Spring Harbor Laboratory, Laureate of Life Sciences Breakthrough Prize 2019, Founder and Director of Stoke Therapeutics Inc., Inventor of &nbsp; Spinraza, the first approved drug for spinal muscular atrophy </em></p><p>11:30 –12:00&nbsp;<strong>Panel Discussion and Questions </strong></p><p>Moderator: Katherine Borden </p><p><em>Canada Research Chair, Professor of Pathology and Cell biology, Université de Montréal </em></p><p>Panel Participants: Adrian Krainer, Erik Sontheimer, Allan Jacobson <br>End of public session and departure of unregistered guests </p><p><strong>Scientific Meeting </strong></p><p>13:00 - 14:00 Lunch for registered guests </p><p><strong>Session 1: RNA Silencing </strong></p><p>Chair: Victor Ambros 14:00 - 14:15 Victor Ambros <br>Introduction and history </p><p>14:15 - 14:30 Michael McManus 14:30 - 14:45 Yukihide Tomari 14:45 - 15:00 Lin He 15:00 - 15:15 Olivia Rissland 15:15 - 15:25 Selection from abstract 15:25 - 15:35 Selection from abstract 15:35 – 16:05 Questions and panel discussions <br>Moderator: Muthiah Manoharan, Alnylam Pharmaceuticals </p><p>16:05 - 16:25 Coffee Break </p><p><strong>Session 2: RNA editing, modification and transcriptomics </strong></p><p>Session Chair: Brenda Bass 16:25 - 16:40 Brenda Bass <br>Introduction and history </p><p>16:40 - 16:55 Tsutomu Suzuki 16:55 - 17:10 Wendy Gilbert 17:10 - 17:25 Pierre Close 17:25 - 17:40 Chuan He 17:40 - 17:50 Selection from abstract 17:50 – 18:00 Selection from abstract 18:00 – 18:30 Questions and panel discussion <br>Moderator: Valerie A. De Crecy-Lagard </p><p>18:30 – 21:00 Dinner </p><p>21:00 – 22:00 Get Together </p><p><strong>Tuesday September 24, 2019 (Day 3) </strong></p><p>07:00 - 08:00&nbsp;Breakfast </p><p><strong>Session 3: Bacterial RNA </strong></p><p>Chair: Susan Gottesman 08:00 - 08:15 Susan Gottesman 08:15 - 08:30 Jörg Vogel 08:30 - 08:45 Eric Masse <br>Introduction and history <br>08:45 - 09:00 Lydia Contreras 09:00 - 09:15 Cynthia Sharma </p><p>09:15 - 09:25 Selection from abstract 09:25 - 09:35 Selection from abstract 09:35 - 10:05 Questions and panel discussion <br>Moderator: Sarah Woodson </p><p>10:05 – 10:35 Coffee Break </p><p><strong>Session 4A: Non-coding RNA </strong></p><p>Chair: David Bartel 10:35 - 10:50 David Bartel <br>Introduction and history </p><p>10:50 - 11:05 Wade Winkler 11:05 - 11:20 Sherif Abou Elela 11:20 - 11:35 Alena Shkumatava 11:35 - 11:50 Lingling Chen 11:50 - 12:00 Selection from abstract 12:00 - 12:10 Selection from abstract 12:10– 12:40 Questions and panel discussion <br>Moderator: TBD </p><p>12:40 - 14:00 Mentor mentee Lunch </p><p><strong>Session 4B: Non-coding RNA </strong></p><p>Chair: Kathy Collins 14:00 - 14:15 Introduction and history <br>Kathy Collins </p><p>14:15 - 14:30 Claus Azzalin 14:30 - 14:45 Jorgen Kjems 14:45 - 15:00 Howard Chang 15:00 - 15:15 Anton Petrov 15:15 - 15:25 Selection from abstract 15:25 - 15:35 Selection from abstract 15:35 – 16:05 Questions and panel discussion <br>Moderator: Raymund Wellinger </p><p>16:05 – 16:35 Coffee break </p><p><strong>Session 5: Ribosome structure and function </strong></p><p>Chair: Joachim Frank 16:35 - 16:50 Introduction and history <br>Joachim Frank </p><p>16:50 - 17:05 Marat Yusupov 17:05 - 17:20 Andrei Korostelev 17:20 - 17:35 Jamie Williamson 17:35 - 17:45 Selection from abstract 17:45 - 17:55 Selection from abstract 17:55 – 18:25 Questions and panel discussion <br>Moderator: Gloria Culver </p><p>18:25 - 18:45 Students’ Poster Promotion Micro talks (2 minutes talks by students) <br>Host: Daniel Lafontaine </p><p>18:45 - 19:45 Dinner 19:45 - 21:45&nbsp;Poster Session I 21:45 - 23:00 Get Together </p><p><strong>Wednesday September 25, 2019 (Day 4) </strong></p><p>07:00 - 08:00 Breakfast </p><p><strong>Session 6: Spliceosome structure and dynamics </strong></p><p>Chair: Reinhardt Lührmann 08:00 - 08:15 Reinhardt Lührmann: Introduction and history </p><p>08:15 - 08:30 Dan Larson 08:30 - 08:45 Kiyoshi Nagai 08:45 - 09:00 Doug Black 09:00- 09:15 Manny Ares 09:15 - 09:25 Selection from abstract 09:25 - 09:35 Selection from abstract 09:35 - 10:05 Questions and panel discussions <br>Moderator: Chris Trotta <br>10:05 - 10:35 Coffee Break </p><p><strong>Session 7: RNA decay and surveillance </strong></p><p>10:35 - 10:50 Introduction and history <br>Allan Jacobson </p><p>10:50 - 11:05 Lori Passmore 11:05 - 11:20 Torben Heick Jensen 11:20 - 11:35 Lynne Maquat 11:35- 11:50 Jianjun Chen 11:50 - 12:00 Selection from abstract 12:00 - 12:10 Selection from abstract 12:10 - 12:40 Questions and panel discussion (applications and future) <br>Moderator: Kristian Baker </p><p>12:40 – 12:55 Group photo 12:55 – 14:40 Lunch 14:40 – 16:40 Poster session II 16:40 – 19:00 Free afternoon </p><p><strong>19:00 - 20:30 </strong>Dinner </p><p>20:30 - 20:40&nbsp;The blue jacket awardees. <br>Martin Bisaillon </p><p>20:40 - 20:50&nbsp;Poster awards presentation by Michelle Scott 20:50 - 21:10&nbsp;RNA biology: the early days <br>Marvin Wickens </p><p><em>Max Perutz Professor of Molecular Biology and Biochemistry, University of Wisconsin </em></p><p>Introduction by Mark Schmitt, SUNY Upstate Medical University </p><p><strong>21:30 - 23:00&nbsp;</strong>Get together <strong>Thursday September 26, 2019 (Day 5) </strong></p><p>07:00 - 08:00&nbsp;Breakfast </p><p><strong>Session 8: RNA and Immunity </strong></p><p>Session Chair: Sandra Wolin 8:00 - 8:15&nbsp;Sandra Wolin </p><p><strong>Introduction and history </strong></p><p>8:15 - 8:30 Daniel Stetson 8:30 - 8:45 Uttiya Basu 8:45 -9:00 Karla Kirkegaard 9:00 - 9:15 Selection from abstract 9:15 - 9:25 Selection from abstract 9:25 - 9:35 Selection from abstract 9:35 - 10:05 Questions and panel discussion <br>Moderator: Jonathan Yingling, </p><p>10:05 - 10:35 Coffee Break </p><p><strong>Session 9: Alternative splicing mechanisms and regulation </strong></p><p>Chair: John Mattick 10:35 - 10:50 John Mattick: Introduction and history </p><p>10:50 - 11:05 Benoit Chabot 11:05 - 11:20 Ben Blencowe 11:20 - 11:35 Kristen Lynch 11:35 - 11:50 Karla Neugebauer 11:50 - 12:00 Selection from abstract 12:00 - 12:10 Selection from abstract 12:10 - 12:40 Questions and Panel discussion (applications and future) <br>Moderator: TBD </p><p>12:40 - 14:40 Lunch </p><p><strong>Session 10: RNA granules and droplets </strong></p><p>Chair: Roy Parker 14:40 - 14:55 Roy Parker 14:55 - 15:10 Mark Ashe 15:10 - 15:25 Graciela L. Boccaccio 15:25 - 15:40 Ross Buchan 15:40 - 15:50 Selection from abstract 15:50 - 16:00 Selection from abstract 16:00 - 16:30 Questions and Panel discussion (applications and future) <br>Moderator: Rachel Meyers </p><p>16:30 - 17:00 Coffee break </p><p><strong>Session 11: RNA structure, evolution, aptamer and catalytic RNA </strong></p><p>Chair: Larry Gold 17:00 - 17:15 Larry Gold 17:15 - 17:30 Jack Szostak 17:30 - 17:45 Adrian R. Ferré-D’Amare 17:45 - 18:00 Alan Lambowitz 18:00 - 18:15 David Mathews 18:15 -&nbsp;18:45 Questions and panel discussion <br>Moderator: TBD <br>18:45 – 19:20 Students choice special presentation Andrew Fire </p><p><strong>19:30 - 20:30&nbsp;Closing Gala and Awards Ceremony </strong></p><p>Host: Francois Bachand, <em>Director of the </em>Université de Sherbrooke Center of RNA Biology, member of Université de Sherbrooke RNA group </p><p><strong>20:30 - 20:35&nbsp;The Dean’s Notes </strong></p><p>Dominque Dorion Dean, Faculty of Medicine and Health Sciences, Université de Sherbrooke </p><p><strong>20:35 - 21:10&nbsp;Special presentation of a lifetime of RNA biology </strong></p><p>Phillip Sharp </p><p><em>Professor, Koch Institute for Integrative Cancer Research at MIT </em></p><p>Introduction by Andrew McMillan, Member of the RiboClub, University of Alberta </p><p><strong>21:10 - 21:20&nbsp;Presentation of the life achievement award </strong></p><p>Nahum Sonnenberg </p><p><em>James McGill Professor of Biochemistry, McGill University and HHMI senior international research scholar, </em></p><p><strong>21:20 - 21:25&nbsp;Predicting the future, Closing Remarks </strong></p><p>Benoit Chabot, <em>co-founder of Université de Sherbrooke RNA group </em></p><p><strong>21:25 - 23:30&nbsp;Entertainment and Music show </strong></p><p>Brendan Bell, Member of the <em>Université de Sherbrooke RNA group </em></p><p></p><ul style="display: flex;"><li style="flex:1"><strong>23:30 - </strong></li><li style="flex:1"><strong>Dance </strong></li></ul><p><strong>Friday September 27, 2019 (Day 6) </strong></p><p>07:00 - 09:00 Breakfast </p><p><strong>Departure </strong></p>