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1 RC-6 Internal Dosimetry the Science and Art of Internal Dose
RC-6 Internal Dosimetry The science and art of internal dose assessment H. Doerfel a, A. Andrasi b, M. Bailey c, V. Berkovski d, E. Blanchardon e, C.-M. Castellani f, R. Cruz-Suarez g, G. Etherington c, C. Hurtgen h, B. LeGuen i, I. Malatova j, J. Marsh c, J. Stather c aIDEA System GmbH, Am Burgweg 4, 76227 Karlsruhe, Germany, [email protected] bKFKI Atomic Energy Research Institute, Budapest, Hungary cRadiation Protection Division, Health Protection Agency, Chilton, Didcot, UK dRadiation Protection Institute, Kiev, Ukraine eInstitut de Radioprotection et de Sûreté Nucleaire, Fontenay-aux-Roses, France fENEA Radiation Protection Institute, Bologna, Italia gInternational Atomic Energy Agency, Vienna, Austria hSCK•CEN Belgian Nuclear Research Centre, Mol, Belgium iElectricite de France, Saint-Denis, France jNRPI, Prague, Czech Republic 1 Abstract Doses from intakes of radionuclides cannot be measured but must be assessed from monitoring, such as whole body counting or urinary excretion measurements. Such assessments require application of a biokinetic model and estimation of the exposure time, material properties, etc. Because of the variety of parameters involved, the results of such assessments may vary over a wide range, according to the skill and the experience of the assessor. The refresher course gives an overview over the state of the art of the determination of internal dose. The first part of the course deals with the measuring techniques for individual incorporation monitoring i.e (i) direct measurement of activity in the whole body or organs, (ii) measurement of activity excreted with urine and faeces, and (iii) measurement of activity in the breathing zone or at the workplace, respectively. -
RADIATION EFFECTS and SOURCES What Is Radiation? What Does Radiation Do to Us? Where Does Radiation Come From?
RADIATION EFFECTS and SOURCES What is radiation? What does radiation do to us? Where does radiation come from? United Nations Environment Programme RADIATION EFFECTS and SOURCES What is radiation? What does radiation do to us? Where does radiation come from? United Nations Environment Programme DISCLAIMER This publication is largely based on the findings of the United Nations Scientific Committee on the Effects of Atomic Radiation, a subsidiary body of the United Nations General Assembly and for which the United Nations Environment Pro- gramme provides the secretariat. This publication does not necessarily r epresent the views of the Scientific Committee or of the United Nations Environment Programme. The designations employed and the presentation of the material in this publica- tion do not imply the expression of any opinion whatsoever on the part of the United Nations Environment Programme concerning the legal status of any country, territory, city or area or of its authorities, or concerning delimitation of its frontiers or boundaries. This publication may be reproduced in whole or in part and in any form for educational or non-profit purposes without special permission from the copyright holder, provided acknowledgement of the source is made. The United Nations Environment Programme would appreciate receiving a copy of any publication that uses this publication as a source. No use of this publication may be made for resale or for any other commercial purpose whatsoever without prior permission in writing from the United Nations Environment Programme. The United Nations Environment Programme promotes environmentally sound practices globally and in its own activities. This publication was printed on recycled paper, 100 per cent chlorine free. -
Absorbed Dose in Radioactive Media Outline Introduction Radiation Equilibrium Charged-Particle Equilibrium Limiting Cases
Outline • General dose calculation considerations, Absorbed Dose in Radioactive absorbed fraction Media • Radioactive disintegration processes and associated dose deposition – Alpha disintegration Chapter 5 – Beta disintegration – Electron-capture transitions F.A. Attix, Introduction to Radiological – Internal conversion Physics and Radiation Dosimetry • Summary Introduction Radiation equilibrium • We are interested in calculating the absorbed dose in a. The atomic composition radioactive media, applicable to cases of of the medium is – Dose within a radioactive organ homogeneous – Dose in one organ due to radioactive source in another b. The density of the organ medium is • If conditions of CPE or RE are satisfied, dose homogeneous c. The radioactive source calculation is straightforward is uniformly distributed • Intermediate situation is more difficult but can be d. No external electric or handled at least in approximations magnetic fields are present Charged-particle equilibrium Limiting cases • Emitted radiation typically includes both • Each charged particle of a given type and photons (longer range) and charged energy leaving the volume is replaced by an particles (shorter range) identical particle of the same energy entering • Assume the conditions for RE are satisfied the volume • Consider two • Existence of RE is sufficient condition for CPE limited cases based • Even if RE does not exist CPE may still exist on the size of the (for a very large or a very small volume) radioactive object 1 Limiting cases: small object Limiting -
Basics of Radiation Radiation Safety Orientation Open Source Booklet 1 (June 1, 2018)
Basics of Radiation Radiation Safety Orientation Open Source Booklet 1 (June 1, 2018) Before working with radioactive material, it is helpful to recall… Radiation is energy released from a source. • Light is a familiar example of energy traveling some distance from its source. We understand that a light bulb can remain in one place and the light can move toward us to be detected by our eyes. • The Electromagnetic Spectrum is the entire range of wavelengths or frequencies of electromagnetic radiation extending from gamma rays to the longest radio waves and includes visible light. Radioactive materials release energy with enough power to cause ionizations and are on the high end of the electromagnetic spectrum. • Although our bodies cannot sense ionizing radiation, it is helpful to think ionizing radiation behaves similarly to light. o Travels in straight lines with decreasing intensity farther away from the source o May be reflected off certain surfaces (but not all) o Absorbed when interacting with materials You will be using radioactive material that releases energy in the form of ionizing radiation. Knowing about the basics of radiation will help you understand how to work safely with radioactive material. What is “ionizing radiation”? • Ionizing radiation is energy with enough power to remove tightly bound electrons from the orbit of an atom, causing the atom to become charged or ionized. • The charged atoms can damage the internal structures of living cells. The material near the charged atom absorbs the energy causing chemical bonds to break. Are all radioactive materials the same? No, not all radioactive materials are the same. -
Uranium Fact Sheet
Fact Sheet Adopted: December 2018 Health Physics Society Specialists in Radiation Safety 1 Uranium What is uranium? Uranium is a naturally occurring metallic element that has been present in the Earth’s crust since formation of the planet. Like many other minerals, uranium was deposited on land by volcanic action, dissolved by rainfall, and in some places, carried into underground formations. In some cases, geochemical conditions resulted in its concentration into “ore bodies.” Uranium is a common element in Earth’s crust (soil, rock) and in seawater and groundwater. Uranium has 92 protons in its nucleus. The isotope2 238U has 146 neutrons, for a total atomic weight of approximately 238, making it the highest atomic weight of any naturally occurring element. It is not the most dense of elements, but its density is almost twice that of lead. Uranium is radioactive and in nature has three primary isotopes with different numbers of neutrons. Natural uranium, 238U, constitutes over 99% of the total mass or weight, with 0.72% 235U, and a very small amount of 234U. An unstable nucleus that emits some form of radiation is defined as radioactive. The emitted radiation is called radioactivity, which in this case is ionizing radiation—meaning it can interact with other atoms to create charged atoms known as ions. Uranium emits alpha particles, which are ejected from the nucleus of the unstable uranium atom. When an atom emits radiation such as alpha or beta particles or photons such as x rays or gamma rays, the material is said to be undergoing radioactive decay (also called radioactive transformation). -
Industrial Radiography
RADIATION PROTECTION OF WORKERS Industrial Radiography RADIATION AND RADIOGRAPHS RADIOACTIVE SOURCES PROCEDURES RADIOGRAPHERS DO follow the procedures. Ionizing radiation can pen- Materials of higher den Sealed sources are small þ Safe storage Precautions þ DO use the appropriate equipment, including collimators. in size and contain material etrate objects and create sity absorb more radiation. þ DO confi rm that there are no other people working in the images on photographic The metal components are which emits penetrating area of radiography. fi lm. The technique is revealed inside this tele radiation continuously. Radioactive sources should be kept in a secure, fi re þ DO use clear working signs and signals. called radiography and phone because they have Special containers made þ DO set up the controlled area and the necessary barriers. the processed fi lms are absorbed more radiation of dense metal shielding resistant and adequately shielded storage location þ DO confi rm the location of the source, or that X rays are called radiographs. than the surrounding plastic. are necessary to store, not being generated, by use of a survey meter. when not in use, and should move and manipulate these þ DO secure and store the source or X ray machine when sources. Due to their small be kept separate from other not in use. materials. The storage loca- size and manoeuvrability, Portable and mobile radiographic þ DO wear your personal dosimeter. sealed sources can be containers. ~ tion for X ray machines that used in confined spaces. are not in use is not required to be shielded. OTHER WORKERS Iridium-192 is a common radioactive source used þ DO observe the access restrictions, however remote it may in gamma radiography. -
Forschungszentrum Karlsruhe Third European Intercomparison Exercise
Forschungszentrum Karlsruhe Technik und Umwelt Wissenschaftliche Berichte FZKA 6457 Third European Intercomparison Exercise on Internal Dose Assessment Results of a Research Programme in the Framework of the EULEP/EURADOS Action Group “Derivation of Parameter Values for Application to the New Model of the Human Respiratory Tract for Occupational Exposure” 1997-1999 H. Doerfel, A. Andrasi 1), M. R. Bailey 2), A. Birchall 2), C.-M. Castellani 3), C. Hurtgen 4), N. Jarvis 2), L. Johansson 5), B. LeGuen 6), G. Tarroni 3) Hauptabteilung Sicherheit 1) AERI, Budapest, Hungary 2) NRPB, Chilton Didcot, United Kingdom 3) ENEA, Bologna, Italy 4) CEN/SCK, Mol, Belgium 5) University of Umea, Umea, Sweden 6) EDF-GDF, Saint Denis Cedex, France Forschungszentrum Karlsruhe GmbH, Karlsruhe 2000 Abstract The EULEP/EURADOS Action Group „Derivation of Parameter Values for Application to the New Model of the Human Respiratory Tract for Occupational Exposure“ has initiated a new intercomparison exercise on internal dose assessment. During the last few years the ICRP has developed a new generation of more realistic internal dosimetry models, including the Human Respiratory Tract Model (ICRP Publication 66) and recycling systemic models for actinides. These models have been used to calculate dose coefficients, which have been adopted in the revised EURATOM Directive. This recent intercomparison exercise gave special consideration to the effects of the new models and the choice of input parameters on the assessment of internal doses from monitoring results. It also took into account some aspects which have not been considered in previous exercises, such as air monitoring, natural radionuclides, exposure of the public, artificially created cases and artificially reduced information. -
Development of Chemical Dosimeters Development Of
SUDANSUDAN ACADEMYAGADEMY OFOF SCIENCES(SAS)SGIENGES(SAS) ATOMICATOMIC ENERGYEhTERGYRESEARCHESRESEARCHES COORDINATIONCOORDII\rATI ON COUNCILCOUNCIL - Development of Chemical Dosimeters A dissertation Submitted in a partial Fulfillment of the Requirement forfbr Diploma Degree in Nuclear Science (Chemistry) By FareedFadl Alla MersaniMergani SupervisorDr K.S.Adam MurchMarch 2006 J - - - CONTENTS Subject Page -I - DedicationDedication........ ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... I Acknowledgement ... '" ... ... ... ... ... ... '" ... ... ... ... '" ... '" ....... .. 11II Abstract ... ... ... '" ... ... ... '" ... ... ... ... -..... ... ... ... ... ... ..... III -I Ch-lch-1 DosimetryDosimefry - 1-1t-l IntroductionLntroduction . 1I - 1-2t-2 Principle of Dosimetry '" '" . 2 1-3l-3 DosimetryDosimefiySystems . 3J 1-3-1l-3-l primary standard dosimeters '" . 4 - 1-3-2l-3-Z Reference standard dosimeters ... .. " . 4 1-3-3L-3-3 Transfer standard dosimeters ... ... '" . 4 1-3-4t-3-4 Routine dosimeters . 5 1-4I-4 Measurement of absorbed dose . 6 1-5l-5 Calibration of DosimetryDosimetrvsystemsvstem '" . 6 1-6l-6 Transit dose effects . 8 Ch-2ch-2 Requirements of chemical dosimeters 2-12-l Introduction ... ... ... .............................................. 111l 2-2 Developing of chemical dosimeters ... ... .. ....... ... .. ..... 12t2 2-3 Classification of Dosimetry methods.methods .......................... 14l4 2-4 RequirementsRequiremsnts of ideal chemical dosimeters ,. ... 15 2-5 Types of chemical system . -
General Guidelines for the Estimation of Committed Effective Dose from Incorporation Monitoring Data
Forschungszentrum Karlsruhe in der Helmholtz-Gemeinschaftt Wissenschaftliche Berichte FZKA 7243 General Guidelines for the Estimation of Committed Effective Dose from Incorporation Monitoring Data (Project IDEAS – EU Contract No. FIKR-CT2001-00160) H. Doerfel, A. Andrasi, M. Bailey, V. Berkovski, E. Blanchardon, C.-M. Castellani, C. Hurtgen, B. LeGuen, I. Malatova, J. Marsh, J. Stather Hauptabteilung Sicherheit August 2006 Forschungszentrum Karlsruhe in der Helmholtz-Gemeinschaft Wissenschaftliche Berichte FZKA 7243 GENERAL GUIDELINES FOR THE ESTIMATION OF COMMITTED EFFECTIVE DOSE FROM INCORPORATION MONITORING DATA (Project IDEAS – EU Contract No. FIKR-CT2001-00160) H. Doerfel, A. Andrasi 1, M. Bailey 2, V. Berkovski 3, E. Blanchardon 6, C.-M. Castellani 4, C. Hurtgen 5, B. LeGuen 7, I. Malatova 8, J. Marsh 2, J. Stather 2 Hauptabteilung Sicherheit 1 KFKI Atomic Energy Research Institute, Budapest, Hungary 2 Health Protection Agency, Radiation Protection Division, (formerly National Radiological Protection Board), Chilton, Didcot, United Kingdom 3 Radiation Protection Institute, Kiev, Ukraine 4 ENEA Institute for Radiation Protection, Bologna, Italy 5 Belgian Nuclear Research Centre, Mol, Belgium 7 Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France 8 Electricité de France (EDF), Saint-Denis, France 9 National Radiation Protection Institute, Praha, Czech Republic Forschungszentrum Karlsruhe GmbH, Karlsruhe 2006 Für diesen Bericht behalten wir uns alle Rechte vor Forschungszentrum Karlsruhe GmbH Postfach 3640, 76021 Karlsruhe Mitglied der Hermann von Helmholtz-Gemeinschaft Deutscher Forschungszentren (HGF) ISSN 0947-8620 urn:nbn:de:0005-072434 IDEAS General Guidelines – June 2006 Abstract Doses from intakes of radionuclides cannot be measured but must be assessed from monitoring, such as whole body counting or urinary excretion measurements. -
Measuring Radioactivity
Health Physics Society Public Education Committee Fact Sheet MEASURING RADIOACTIVITY Because ionizing radiation cannot be detected with our human senses, we use various types of instruments and radiation detectors to measure the amount of radiation present. We usually measure both the amount of radioactivity in a radioisotope source, and the ionizing radiation field density being emitted by the source. We define radioactivity as the number of atoms which decay (disintegrate) in a radioisotope sample in a given period of time. The base unit is the Becquerel (Bq) or one disintegration per second (dps). This number is very small and therefore, not very useful. For this reason we use the Curie (Ci) which is 37 billion Bq. Because we often use very large or very small numbers when discussing radioactivity, we use a series o f prefixes which express multiples of 1000. The following table shows some of these prefixes: milli (m) = 1/1,000 kilo (k) = times 1,000 micro (u) = 1/1,000,000 mega (M) = times 1,000,000 nano (n) 1/1,000,000,000 giga (G) times 1,000,000,000 Pico (P) 1/1,000,000,000,000 tera (T) times 1,000,000,000,000 Using the table, a mCi = 1/1000 of a Curie and a GBq 1,000,000,000 Becquerels. To put this in perspective, a normal home smoke detector contains a small sealed source of about 10 uCi (370,000 Bq) of radioactivity. Ionizing radiation fields are expressed in units of Roentgens (R) which is equivalent to the number of atoms of a gas which are ionized. -
The International Commission on Radiological Protection: Historical Overview
Topical report The International Commission on Radiological Protection: Historical overview The ICRP is revising its basic recommendations by Dr H. Smith Within a few weeks of Roentgen's discovery of gamma rays; 1.5 roentgen per working week for radia- X-rays, the potential of the technique for diagnosing tion, affecting only superficial tissues; and 0.03 roentgen fractures became apparent, but acute adverse effects per working week for neutrons. (such as hair loss, erythema, and dermatitis) made hospital personnel aware of the need to avoid over- Recommendations in the 1950s exposure. Similar undesirable acute effects were By then, it was accepted that the roentgen was reported shortly after the discovery of radium and its inappropriate as a measure of exposure. In 1953, the medical applications. Notwithstanding these observa- ICRU recommended that limits of exposure should be tions, protection of staff exposed to X-rays and gamma based on consideration of the energy absorbed in tissues rays from radium was poorly co-ordinated. and introduced the rad (radiation absorbed dose) as a The British X-ray and Radium Protection Committee unit of absorbed dose (that is, energy imparted by radia- and the American Roentgen Ray Society proposed tion to a unit mass of tissue). In 1954, the ICRP general radiation protection recommendations in the introduced the rem (roentgen equivalent man) as a unit early 1920s. In 1925, at the First International Congress of absorbed dose weighted for the way different types of of Radiology, the need for quantifying exposure was radiation distribute energy in tissue (called the dose recognized. As a result, in 1928 the roentgen was equivalent in 1966). -
MIRD Pamphlet No. 22 - Radiobiology and Dosimetry of Alpha- Particle Emitters for Targeted Radionuclide Therapy
Alpha-Particle Emitter Dosimetry MIRD Pamphlet No. 22 - Radiobiology and Dosimetry of Alpha- Particle Emitters for Targeted Radionuclide Therapy George Sgouros1, John C. Roeske2, Michael R. McDevitt3, Stig Palm4, Barry J. Allen5, Darrell R. Fisher6, A. Bertrand Brill7, Hong Song1, Roger W. Howell8, Gamal Akabani9 1Radiology and Radiological Science, Johns Hopkins University, Baltimore MD 2Radiation Oncology, Loyola University Medical Center, Maywood IL 3Medicine and Radiology, Memorial Sloan-Kettering Cancer Center, New York NY 4International Atomic Energy Agency, Vienna, Austria 5Centre for Experimental Radiation Oncology, St. George Cancer Centre, Kagarah, Australia 6Radioisotopes Program, Pacific Northwest National Laboratory, Richland WA 7Department of Radiology, Vanderbilt University, Nashville TN 8Division of Radiation Research, Department of Radiology, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark NJ 9Food and Drug Administration, Rockville MD In collaboration with the SNM MIRD Committee: Wesley E. Bolch, A Bertrand Brill, Darrell R. Fisher, Roger W. Howell, Ruby F. Meredith, George Sgouros (Chairman), Barry W. Wessels, Pat B. Zanzonico Correspondence and reprint requests to: George Sgouros, Ph.D. Department of Radiology and Radiological Science CRB II 4M61 / 1550 Orleans St Johns Hopkins University, School of Medicine Baltimore MD 21231 410 614 0116 (voice); 413 487-3753 (FAX) [email protected] (e-mail) - 1 - Alpha-Particle Emitter Dosimetry INDEX A B S T R A C T.........................................................................................................................