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CHAPTER 5: THE

Copyright © 2010 Pearson Education, Inc. OVERALL STRUCTURE 3 LAYERS

Copyright © 2010 Pearson Education, Inc. Figure 5.1 Skin structure.

Hair shaft Dermal papillae Subpapillary vascular plexus Papillary layer Pore Appendages of skin

Dermis Reticular • Eccrine sweat layer gland • Hypodermis • Sebaceous (oil) gland (superficial ) • follicle Nervous structures • Hair root • Sensory nerve fiber Cutaneous vascular • Pacinian corpuscle plexus • receptor Adipose tissue (root hair plexus)

Copyright © 2010 Pearson Education, Inc. EPIDERMIS 4 (or 5) LAYERS

Copyright © 2010 Pearson Education, Inc. Figure 5.2 The main structural features of the skin epidermis.

Keratinocytes

Stratum corneum

Stratum granulosum

Epidermal dendritic cell Tactile (Merkel) cell Sensory nerve ending (a) Dermis Desmosomes Melanocyte (b) Melanin granule

Copyright © 2010 Pearson Education, Inc. DERMIS 2 LAYERS

Copyright © 2010 Pearson Education, Inc. Figure 5.3 The two regions of the dermis.

Dermis

(b) Papillary layer of dermis, SEM (22,700x)

(a) Light micrograph of thick skin identifying the extent of the dermis, (50x)

(c) Reticular layer of dermis, SEM (38,500x)

Copyright © 2010 Pearson Education, Inc. Figure 5.3a The two regions of the dermis.

Dermis

(a) Light micrograph of thick skin identifying the extent of the dermis, (50x)

Copyright © 2010 Pearson Education, Inc. Q1: The type of gland which secretes its products onto a surface is an ______gland. 1) Endocrine 2) Exocrine 3) Merocrine 4) Holocrine

Copyright © 2010 Pearson Education, Inc. Q2: The embryonic tissue which gives rise to muscle and most connective tissue is… 1) Ectoderm 2) Endoderm 3) Mesoderm

Copyright © 2010 Pearson Education, Inc. Q3: A melanocyte would be found in the _____ of the epidermis. 1) Stratum basale 2) Stratum spinosum 3) 4) 5) 6) Reticular layer 7) Papillary layer

Copyright © 2010 Pearson Education, Inc. Q4: The main cell type in the epidermis is the...

1) Melanocyte 2) Langerhans Cell 3) Merkel Cell 4) Dendritic Cell 5)

Copyright © 2010 Pearson Education, Inc. Q5: The bulk of the dermis is the ______layer.

1) Epidermal 2) Hypodermal 3) Reticular 4) Papillary

Copyright © 2010 Pearson Education, Inc. SKIN COLOR 3 PIGMENTS

Copyright © 2010 Pearson Education, Inc. SKIN APPENDAGES

Copyright © 2010 Pearson Education, Inc. CUTANEOUS GLANDS

Copyright © 2010 Pearson Education, Inc. Figure 5.5 Cutaneous glands.

Sweat pore

Sebaceous gland

Dermal Eccrine connective gland tissue duct Hair in hair follicle Duct Dermal connective tissue Secretory cells

(a) Photomicrograph of a (b) Photomicrograph of sectioned sebaceous a sectioned eccrine gland (220x) gland (220x)

Copyright © 2010 Pearson Education, Inc. A in your axilla (armpit) is which type of gland? 1) Sebaceous 2) Apocrine 3) Eccrine

Copyright © 2010 Pearson Education, Inc. HAIR FOLLICLES

Copyright © 2010 Pearson Education, Inc. Figure 5.6a Structure of a hair and hair follicle.

Follicle wall • Connective tissue • Glassy membrane • External epithelial root sheath • Internal epithelial root sheath Hair shaft Hair • Arrector pili (a) Diagram of a cross section of Sebaceous a hair within its follicle gland Hair root Hair bulb

Copyright © 2010 Pearson Education, Inc. Figure 5.6b Structure of a hair and hair follicle. Follicle wall • Connective tissue root sheath • Glassy membrane • External epithelial root sheath • Internal epithelial root sheath Hair • Cuticle • Cortex Hair shaft • Medulla

Arrector (b) Photomicrograph of a cross pili section of a hair and hair Sebaceous follicle (250x) gland Hair root Hair bulb

Copyright © 2010 Pearson Education, Inc. Figure 5.6c Structure of a hair and hair follicle. Hair shaft

Arrector pili Sebaceous gland Hair root Follicle wall Hair bulb • Connective tissue root sheath • Glassy membrane • External epithelial root sheath • Internal epithelial root sheath Hair root • Cuticle • Cortex • Medulla Hair papilla Melanocyte

Subcutaneous adipose tissue (c) Diagram of a longitudinal view of the expanded hair bulb of the follicle, which encloses the matrix

Copyright © 2010 Pearson Education, Inc. Figure 5.6d Structure of a hair and hair follicle.

Follicle wall • Connective tissue root sheath Hair shaft • Glassy membrane • External epithelial root sheath • Internal epithelial root sheath Arrector Hair root pili • Cuticle Sebaceous • Cortex gland • Medulla Hair root Hair matrix Hair bulb Hair papilla

Subcutaneous adipose tissue (d) Photomicrograph of longitudinal view of the hair bulb in the follicle (160x)

Copyright © 2010 Pearson Education, Inc. Which layer of a hair follicle wall is thickest?

1) Connective tissue root sheath 2) External epithelial root sheath 3) Internal epithelial root sheath

Copyright © 2010 Pearson Education, Inc. NAILS

Copyright © 2010 Pearson Education, Inc. Figure 5.7 Structure of a . Lateral Lunule nail fold

(a) Free edge Body of nail of nail (cuticle) Proximal nail fold Nail bed Root of nail Nail matrix

(b) Phalanx (bone of fingertip)

Copyright © 2010 Pearson Education, Inc. What is the scientific name for the cuticle?

1) Eponychium 2) Hyponychium 3) Lunule 4) Nail matrix

Copyright © 2010 Pearson Education, Inc. FUNCTIONS

Copyright © 2010 Pearson Education, Inc. DISEASES (“HOMEOSTATIC IMBALANCES”)

Copyright © 2010 Pearson Education, Inc. SKIN CANCER

Copyright © 2010 Pearson Education, Inc. Figure 5.8 Photographs of skin cancers.

Copyright © 2010 Pearson Education, Inc. True or false: all skin cancers start out looking like moles. 1) True 2) False

Copyright © 2010 Pearson Education, Inc. SKIN BURNS

Copyright © 2010 Pearson Education, Inc. Figure 5.10 Partial thickness and full thickness burns.

1st degree 3rd burn degree burn

2nd degree burn

(a) Skin bearing partial (b) Skin bearing full thickness burn (1st and thickness burn 2nd degree burns) (3rd degree burn)

Copyright © 2010 Pearson Education, Inc. Figure 5.9 Estimating the extent and severity of burns using the rule of nines. Totals 4 1 /2 % Anterior and posterior head and neck, 9% Anterior and posterior upper limbs, 18% Anterior Anterior and posterior 4 1 /2 % trunk, 4 1 /2 % 18% trunk, 36%

9% 9% (Perineum, 1%)

Anterior and posterior lower limbs, 36% 100%

Copyright © 2010 Pearson Education, Inc. A patient playing with a lighter and a can of hairspray experienced second- and third- degree burns covering his entire left arm. What percent of the body was burned?

1) 4.5 % 2) 9% 3) 18% 4) 8%

Copyright © 2010 Pearson Education, Inc.