DOCSLIB.ORG

Pharmaceutical Appendix to the Harmonized Tariff Schedule

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text

Load more

)&f1y3X PHARMACEUTICAL APPENDIX TO THE HARMONIZED TARIFF SCHEDULE )&f1y3X PHARMACEUTICAL APPENDIX TO THE TARIFF SCHEDULE 3 Table 1. This table enumerates products described by International Non-proprietary Names (INN) which shall be entered free of duty under general note 13 to the tariff schedule. The Chemical Abstracts Service (CAS) registry numbers also set forth in this table are included to assist in the identification of the products concerned. For purposes of the tariff schedule, any references to a product enumerated in this table includes such product by whatever name known. Product CAS No. Product CAS No. ABAMECTIN 65195-55-3 ACTODIGIN 36983-69-4 ABANOQUIL 90402-40-7 ADAFENOXATE 82168-26-1 ABCIXIMAB 143653-53-6 ADAMEXINE 54785-02-3 ABECARNIL 111841-85-1 ADAPALENE 106685-40-9 ABITESARTAN 137882-98-5 ADAPROLOL 101479-70-3 ABLUKAST 96566-25-5 ADATANSERIN 127266-56-2 ABUNIDAZOLE 91017-58-2 ADEFOVIR 106941-25-7 ACADESINE 2627-69-2 ADELMIDROL 1675-66-7 ACAMPROSATE 77337-76-9 ADEMETIONINE 17176-17-9 ACAPRAZINE 55485-20-6 ADENOSINE PHOSPHATE 61-19-8 ACARBOSE 56180-94-0 ADIBENDAN 100510-33-6 ACEBROCHOL 514-50-1 ADICILLIN 525-94-0 ACEBURIC ACID 26976-72-7 ADIMOLOL 78459-19-5 ACEBUTOLOL 37517-30-9 ADINAZOLAM 37115-32-5 ACECAINIDE 32795-44-1 ADIPHENINE 64-95-9 ACECARBROMAL 77-66-7 ADIPIODONE 606-17-7 ACECLIDINE 827-61-2 ADITEREN 56066-19-4 ACECLOFENAC 89796-99-6 ADITOPRIM 56066-63-8 ACEDAPSONE 77-46-3 ADOSOPINE 88124-26-9 ACEDIASULFONE SODIUM 127-60-6 ADOZELESIN 110314-48-2 ACEDOBEN 556-08-1 ADRAFINIL 63547-13-7 ACEFLURANOL 80595-73-9 ADRENALONE 99-45-6 ACEFURTIAMINE 10072-48-7 AFALANINE 2901-75-9 ACEFYLLINE PIPERAZINE 18428-63-2 AFELIMOMAB 156227-98-4 ACEFYLLINE CLOFIBROL 70788-27-1 AFLOQUALONE 56287-74-2 ACEGLATONE 642-83-1 AFOVIRSEN 151356-08-0 ACEGLUTAMIDE 2490-97-3 AFUROLOL 65776-67-2 ACEMANNAN 110042-95-0 AGANODINE 86696-87-9 ACEMETACIN 53164-05-9 AGLEPRISTONE 124478-60-0 ACENEURAMIC ACID 131-48-6 AKLOMIDE 3011-89-0 ACENOCOUMAROL 152-72-7 ALACEPRIL 74258-86-9 ACEPERONE 807-31-8 ALAFOSFALIN 60668-24-8 ACEPROMAZINE 61-00-7 ALANINE 56-41-7 ACEPROMETAZINE 13461-01-3 ALANOSINE 5854-93-3 ACEQUINOLINE 42465-20-3 ALAPROCLATE 60719-82-6 ACESULFAME 33665-90-6 ALAZANINE TRICLOFENATE 5779-59-9 ACETAMINOSALOL 118-57-0 ALBENDAZOLE OXIDE 54029-12-8 ACETARSOL 97-44-9 ALBENDAZOLE 54965-21-8 ACETAZOLAMIDE 59-66-5 ALBIFYLLINE 107767-55-5 ACETERGAMINE 3031-48-9 ALBUTOIN 830-89-7 ACETIAMINE 299-89-8 ALCLOFENAC 22131-79-9 ACETIROMATE 2260-08-4 ALCLOMETASONE 67452-97-5 ACETOHEXAMIDE 968-81-0 ALCLOXA 1317-25-5 ACETOHYDROXAMIC ACID 546-88-3 ALCURONIUM CHLORIDE 15180-03-7 ACETOPHENAZINE 2751-68-0 ALDESULFONE SODIUM 144-75-2 ACETORPHINE 25333-77-1 ALDIOXA 5579-81-7 ACETRYPTINE 3551-18-6 ALDOSTERONE 52-39-1 ACETYLCHOLINE CHLORIDE 60-31-1 ALENDRONIC ACID 66376-36-1 ACETYLCYSTEINE 616-91-1 ALENTEMOL 112891-97-1 ACETYLDIGITOXIN 1111-39-3 ALEPRIDE 66564-15-6 ACETYLLEUCINE 99-15-0 ALESTRAMUSTINE 139402-18-9 ACETYLMETHADOL 509-74-0 ALEXIDINE 22573-93-9 ACEVALTRATE 25161-41-5 ALEXITOL SODIUM 66813-51-2 ACEXAMIC ACID 57-08-9 ALFACALCIDOL 41294-56-8 ACICLOVIR 59277-89-3 ALFADEX 10016-20-3 ACIFRAN 72420-38-3 ALFADOLONE 14107-37-0 ACIPIMOX 51037-30-0 ALFAPROSTOL 74176-31-1 ACITAZANOLAST 114607-46-4 ALFAXALONE 23930-19-0 ACITEMATE 101197-99-3 ALFENTANIL 71195-58-9 ACITRETIN 55079-83-9 ALFETAMINE 4255-23-6 ACIVICIN 42228-92-2 ALFUZOSIN 81403-80-7 ACLANTATE 39633-62-0 ALGELDRATE 1330-44-5 ACLARUBICIN 57576-44-0 ALGESTONE 595-77-7 ACLATONIUM NAPADISILATE 55077-30-0 ALGLUCERASE 143003-46-7 ACODAZOLE 79152-85-5 ALIBENDOL 26750-81-2 ACONIAZIDE 13410-86-1 ALICONAZOLE 63824-12-4 ACOXATRINE 748-44-7 ALIFEDRINE 78756-61-3 ACRIDOREX 47487-22-9 ALIFLURANE 56689-41-9 ACRIFLAVINIUM CHLORIDE 8063-24-9 ALIMADOL 52742-40-2 ACRIHELLIN 67696-82-6 ALIMEMAZINE 84-96-8 ACRISORCIN 7527-91-5 ALINIDINE 33178-86-8 ACRIVASTINE 87848-99-5 ALIPAMIDE 3184-59-6 ACROCINONIDE 28971-58-6 ALIZAPRIDE 59338-93-1 ACRONINE 7008-42-6 ALLETORPHINE 23758-80-7 ACTAGARDIN ALLOBARBITAL 52-43-7 ACTAPLANIN 37305-75-2 ALLOCLAMIDE 5486-77-1 ACTARIT 18699-02-0 ALLOCUPREIDE SODIUM 5965-40-2 ACTINOQUINOL 15301-40-3 ALLOMETHADIONE 526-35-2 ACTISOMIDE 96914-39-5 ALLOPURINOL 315-30-0 )&f1y3X PHARMACEUTICAL APPENDIX TO THE TARIFF SCHEDULE 4 Table 1 (con.) Product CAS Number Product CAS Number ALLYLESTRENOL 432-60-0 AMFONELIC ACID 15180-02-6 ALLYLPRODINE 25384-17-2 AMICARBALIDE 3459-96-9 ALLYLTHIOUREA 109-57-9 AMICIBONE 23271-63-8 ALMADRATE SULFATE 60239-66-9 AMICYCLINE 5874-95-3 ALMAGATE 66827-12-1 AMIDANTEL 49745-00-8 ALMAGODRATE AMIDAPSONE 3569-77-5 ALMASILATE 71205-22-6 AMIDEFRINE MESILATE 1421-68-7 ALMECILLIN 87-09-2 AMIFLAMINE 77518-07-1 ALMESTRONE 10448-96-1 AMIFLOVERINE 54063-24-0 ALMINOPROFEN 39718-89-3 AMIFLOXACIN 86393-37-5 ALMITRINE 27469-53-0 AMIFOSTINE 20537-88-6 ALMOKALANT 123955-10-2 AMIKACIN 37517-28-5 ALMOXATONE 84145-89-1 AMIKHELLINE 4439-67-2 ALNESPIRONE 138298-79-0 AMILORIDE 2609-46-3 ALNIDITAN 152317-89-0 AMINDOCATE 31386-24-0 ALONACIC 105292-70-4 AMINEPTINE 57574-09-1 ALONIMID 2897-83-8 AMINITROZOLE 140-40-9 ALORACETAM 119610-26-3 AMINOACRIDINE 90-45-9 ALOSETRON 122852-42-0 AMINOCAPROIC ACID 60-32-2 ALOVUDINE 25526-93-6 AMINOETHYL NITRATE 646-02-6 ALOXIPRIN 9014-67-9 AMINOGLUTETHIMIDE 125-84-8 ALOXISTATIN 88321-09-9 AMINOMETRADINE 642-44-4 ALOZAFONE 65899-72-1 AMINOPHENAZONE 58-15-1 ALPERTINE 27076-46-6 AMINOPHENAZONE CYCLAMATE 747-30-8 ALPHACETYLMETHADOL 17199-58-5 AMINOPHYLLINE 317-34-0 ALPHAMEPRODINE 468-51-9 AMINOPROMAZINE 58-37-7 ALPHAMETHADOL 17199-54-1 AMINOPTERIN SODIUM 58602-66-7 ALPHAPRODINE 77-20-3 AMINOQUINOL 10023-54-8 ALPIDEM 82626-01-5 AMINOQUINURIDE 3811-56-1 ALPIROPRIDE 81982-32-3 AMINOREX 2207-50-3 ALPRAFENONE 124316-02-5 AMINOTHIAZOLE 96-50-4 ALPRAZOLAM 28981-97-7 AMINOXYTRIPHENE 5585-64-8 ALPRENOLOL 13655-52-2 AMIODARONE 1951-25-3 ALPROSTADIL 745-65-3 AMIPERONE 1580-71-8 ALRESTATIN 51411-04-2 AMIPHENAZOLE 490-55-1 ALSACTIDE 34765-96-3 AMIPIZONE 69635-63-8 ALTANSERIN 76330-71-7 AMIPRILOSE 56824-20-5 ALTAPIZONE 93277-96-4 AMIQUINSIN 13425-92-8 ALTECONAZOLE 93479-96-0 AMISOMETRADINE 550-28-7 ALTEPLASE 105857-23-6 AMISULPRIDE 71675-85-9 ALTIZIDE 5588-16-9 AMITEROL 54063-25-1 ALTOQUALINE 121029-11-6 AMITIVIR 111393-84-1 ALTRENOGEST 850-52-2 AMITRAZ 33089-61-1 ALTRETAMINE 645-05-6 AMITRIPTYLINE 50-48-6 ALTUMOMAB 156586-92-4 AMITRIPTYLINOXIDE 4317-14-0 ALUMINIUM CLOFIBRATE 24818-79-9 AMIXETRINE 24622-72-8 ALUSULF 61115-28-4 AMLEXANOX 68302-57-8 ALVERINE 150-59-4 AMLODIPINE 88150-42-9 ALVIRCEPT SUDOTOX 137487-62-8 AMOBARBITAL 57-43-2 AMADINONE 30781-27-2 AMOCARZINE 36590-19-9 AMAFOLONE 50588-47-1 AMODIAQUINE 86-42-0 AMANOZINE 537-17-7 AMOGASTRIN 16870-37-4 AMANTADINE 768-94-5 AMOLANONE 76-65-3 AMANTANIUM BROMIDE 58158-77-3 AMONAFIDE 69408-81-7 AMANTOCILLIN 10004-67-8 AMOPROXAN 22661-76-3 AMBAMUSTINE 85754-59-2 AMOPYROQUINE 550-81-2 AMBASILIDE 83991-25-7 AMOROLFINE 78613-35-1 AMBAZONE 539-21-9 AMOSCANATE 26328-53-0 AMBENONIUM CHLORIDE 115-79-7 AMOSULALOL 85320-68-9 AMBENOXAN 2455-84-7 AMOXAPINE 14028-44-5 AMBICROMIL 58805-38-2 AMOXECAINE 553-65-1 AMBOMYCIN 1402-81-9 AMOXICILLIN 26787-78-0 AMBROXOL 18683-91-5 AMOXYDRAMINE CAMSILATE 15350-99-9 AMBRUTICIN 58857-02-6 AMPEROZIDE 75558-90-6 AMBUCAINE 119-29-9 AMPHENIDONE 134-37-2 AMBUCETAMIDE 519-88-0 AMPHOTALIDE 1673-06-9 AMBUSIDE 3754-19-6 AMPHOTERICIN B 1397-89-3 AMCINAFAL 3924-70-7 AMPICILLIN 69-53-4 AMCINAFIDE 7332-27-6 AMPIROXICAM 99464-64-9 AMCINONIDE 51022-69-6 AMPROLIUM 121-25-5 AMEBUCORT 83625-35-8 AMPYRIMINE 5587-93-9 AMEDALIN 22136-26-1 AMPYZINE 5214-29-9 AMELTOLIDE 787-93-9 AMQUINATE 17230-85-2 AMESERGIDE 121588-75-8 AMRINONE 60719-84-8 AMETANTRONE 64862-96-0 AMRUBICIN 110267-81-7 AMEZEPINE 60575-32-8 AMSACRINE 51264-14-3 AMEZINIUM METILSULFATE 30578-37-1 AMTOLMETIN GUACIL 87344-06-7 AMFEBUTAMONE 34911-55-2 AMYLMETACRESOL 1300-94-3 AMFECLORAL 5581-35-1 ANAGESTONE 2740-52-5 AMFENAC 51579-82-9 ANAGRELIDE 68475-42-3 AMFEPENTOREX 15686-27-8 ANAKINRA 143090-92-0 AMFEPRAMONE 90-84-6 ANARITIDE 95896-08-5 AMFETAMINE 300-62-9 ANASTROZOLE 120511-73-1 AMFETAMINIL 17590-01-1 ANAXIRONE 77658-97-0 AMFLUTIZOLE 82114-19-0 ANAZOCINE 15378-99-1 AMFOMYCIN 1402-82-0 ANAZOLENE SODIUM 3861-73-2 )&f1y3X PHARMACEUTICAL APPENDIX TO THE TARIFF SCHEDULE 5 Table 1 (con.) ProductCAS Number Product CAS Number ANCAROLOL 75748-50-4 ATAPROST 83997-19-7 ANCITABINE 31698-14-3 ATENOLOL 29122-68-7 ANCROD 9046-56-4 ATEVIRDINE 136816-75-6 ANDOLAST 132640-22-3 ATEXAKIN ALFA 143631-61-2 ANDROSTANOLONE 521-18-6 ATIBEPRONE 153420-96-3 ANGIOTENSIN II 4474-91-3 ATIPAMEZOLE 104054-27-5 ANGIOTENSINAMIDE 53-73-6 ATIPROSIN 89303-63-9 ANIDOXIME 34297-34-2 ATOLIDE 16231-75-7 ANILAMATE 5591-49-1 ATORVASTATIN 134523-00-5 ANILERIDINE 144-14-9 ATOSIBAN 90779-69-4 ANILOPAM 53716-46-4 ATOVAQUONE 95233-18-4 ANIPAMIL 83200-10-6 ATRACURIUM BESILATE 64228-81-5 ANIRACETAM 72432-10-1 ATRIMUSTINE 75219-46-4 ANIROLAC 66635-85-6 ATRINOSITOL 28841-62-5 ANISACRIL 5129-14-6 ATROMEPINE 428-07-9 ANISINDIONE 117-37-3 ATROPINE OXIDE 4438-22-6 ANISOPIROL 442-03-5 ATROPINE METHONITRATE 52-88-0 ANISTREPLASE 81669-57-0 AURANOFIN 34031-32-8 ANITRAZAFEN 63119-27-7 AUROTHIOGLYCANIDE 16925-51-2 ANPIRTOLINE 98330-05-3 AVICATONIN 103451-84-9 ANSOXETINE 79130-64-6 AVILAMYCIN 11051-71-1 ANTAFENITE 15301-45-8 AVIZAFONE 65617-86-9 ANTAZOLINE 91-75-8 AVOBENZONE 70356-09-1 ANTAZONITE 25422-75-7 AVOPARCIN 37332-99-3 ANTELMYCIN 1402-84-2 AVRIDINE 35607-20-6 ANTHIOLIMINE 305-97-5 AXAMOZIDE 85076-06-8 ANTIENITE 5029-05-0 AZABON 1150-20-5 ANTITHROMBIN III, HUMAN 9000-94-6 AZABUPERONE 2856-81-7 ANTRAFENINE 55300-29-3 AZACITIDINE 320-67-2 ANTRAMYCIN 4803-27-4 AZACLORZINE 49864-70-2 APAFANT 105219-56-5 AZACONAZOLE
Recommended publications
  • (12) United States Patent (10) Patent No.: US 9,498,481 B2 Rao Et Al

    (12) United States Patent (10) Patent No.: US 9,498,481 B2 Rao Et Al

    USOO9498481 B2 (12) United States Patent (10) Patent No.: US 9,498,481 B2 Rao et al. (45) Date of Patent: *Nov. 22, 2016 (54) CYCLOPROPYL MODULATORS OF P2Y12 WO WO95/26325 10, 1995 RECEPTOR WO WO99/O5142 2, 1999 WO WOOO/34283 6, 2000 WO WO O1/92262 12/2001 (71) Applicant: Apharaceuticals. Inc., La WO WO O1/922.63 12/2001 olla, CA (US) WO WO 2011/O17108 2, 2011 (72) Inventors: Tadimeti Rao, San Diego, CA (US); Chengzhi Zhang, San Diego, CA (US) OTHER PUBLICATIONS Drugs of the Future 32(10), 845-853 (2007).* (73) Assignee: Auspex Pharmaceuticals, Inc., LaJolla, Tantry et al. in Expert Opin. Invest. Drugs (2007) 16(2):225-229.* CA (US) Wallentin et al. in the New England Journal of Medicine, 361 (11), 1045-1057 (2009).* (*) Notice: Subject to any disclaimer, the term of this Husted et al. in The European Heart Journal 27, 1038-1047 (2006).* patent is extended or adjusted under 35 Auspex in www.businesswire.com/news/home/20081023005201/ U.S.C. 154(b) by Od en/Auspex-Pharmaceuticals-Announces-Positive-Results-Clinical M YW- (b) by ayS. Study (published: Oct. 23, 2008).* This patent is Subject to a terminal dis- Concert In www.concertpharma. com/news/ claimer ConcertPresentsPreclinicalResultsNAMS.htm (published: Sep. 25. 2008).* Concert2 in Expert Rev. Anti Infect. Ther. 6(6), 782 (2008).* (21) Appl. No.: 14/977,056 Springthorpe et al. in Bioorganic & Medicinal Chemistry Letters 17. 6013-6018 (2007).* (22) Filed: Dec. 21, 2015 Leis et al. in Current Organic Chemistry 2, 131-144 (1998).* Angiolillo et al., Pharmacology of emerging novel platelet inhibi (65) Prior Publication Data tors, American Heart Journal, 2008, 156(2) Supp.
  • Lifestyle Drugs” for Men and Women

    Lifestyle Drugs” for Men and Women

    Development of “Lifestyle Drugs” for Men and Women Armin Schultz CRS - Clinical Research Services Mannheim GmbH AGAH Annual Meeting 2012, Leipzig, March 01 - 02 Lifestyle drugs Smart drugs, Quality-of-life drugs, Vanity drugs etc. Lifestyle? Lifestyle-Drugs? Active development? Discovery by chance? AGAH Annual Meeting 2012, Leipzig, March 01 - 02 Lifestyle A lifestyle is a characteristic bundle of behaviors that makes sense to both others and oneself in a given time and place, including social relations, consumption, entertainment, and dress. The behaviors and practices within lifestyles are a mixture of habits, conventional ways of doing things, and reasoned actions „Ein Lebensstil ist [...] der regelmäßig wiederkehrende Gesamtzusammenhang der Verhaltensweisen, Interaktionen, Meinungen, Wissensbestände und bewertenden Einstellungen eines Menschen“ (Hradil 2005: 46) Different definitions in social sciences, philosophy, psychology or medicine AGAH Annual Meeting 2012, Leipzig, March 01 - 02 Lifestyle Many “subdivisions” LOHAS: “Lifestyles of Health and Sustainability“ LOVOS: “Lifestyles of Voluntary Simplicity“ SLOHAS: “Slow Lifestyles of Happiness and Sustainability” PARKOS: “Partizipative Konsumenten“ ……. ……. ……. AGAH Annual Meeting 2012, Leipzig, March 01 - 02 Lifestyle drugs Lifestyle drug is an imprecise term commonly applied to medications which treat non-life threatening and non-painful conditions such as baldness, impotence, wrinkles, or acne, without any medical relevance at all or only minor medical relevance relative to others. Desire for increase of personal well-being and quality of life It is sometimes intended as a pejorative, bearing the implication that the scarce medical research resources allocated to develop such drugs were spent frivolously when they could have been better spent researching cures for more serious medical conditions.
  • Novel Approaches for the Treatment of Alzheimer's and Parkinson's Disease

    Novel Approaches for the Treatment of Alzheimer's and Parkinson's Disease

    International Journal of Molecular Sciences Review Novel Approaches for the Treatment of Alzheimer’s and Parkinson’s Disease Michiel Van Bulck 1,2 , Ana Sierra-Magro 1,2, Jesus Alarcon-Gil 1, Ana Perez-Castillo 1,2 and Jose A. Morales-Garcia 1,2,3,* 1 Instituto de Investigaciones Biomédicas (CSIC-UAM), Arturo Duperier, 4. 28029 Madrid, Spain; [email protected] (M.V.B.); [email protected] (A.S.-M.); [email protected] (J.A.-G.); [email protected] (A.P.-C.) 2 Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Valderrebollo, 5, 28031 Madrid, Spain 3 Departamento de Biología Celular, Facultad de Medicina, Universidad Complutense de Madrid (UCM), Plaza Ramón y Cajal s/n, 28040 Madrid, Spain * Correspondence: [email protected] Received: 31 December 2018; Accepted: 3 February 2019; Published: 8 February 2019 Abstract: Neurodegenerative disorders affect around one billion people worldwide. They can arise from a combination of genomic, epigenomic, metabolic, and environmental factors. Aging is the leading risk factor for most chronic illnesses of old age, including Alzheimer’s and Parkinson’s diseases. A progressive neurodegenerative process and neuroinflammation occur, and no current therapies can prevent, slow, or halt disease progression. To date, no novel disease-modifying therapies have been shown to provide significant benefit for patients who suffer from these devastating disorders. Therefore, early diagnosis and the discovery of new targets and novel therapies are of upmost importance. Neurodegenerative diseases, like in other age-related disorders, the progression of pathology begins many years before the onset of symptoms. Many efforts in this field have led to the conclusion that exits some similar events among these diseases that can explain why the aging brain is so vulnerable to suffer neurodegenerative diseases.
  • Therapeutic and Prophylactic Use of Oral, Low-Dose Ifns in Species of Veterinary Interest: Back to the Future

    Therapeutic and Prophylactic Use of Oral, Low-Dose Ifns in Species of Veterinary Interest: Back to the Future

    veterinary sciences Review Therapeutic and Prophylactic Use of Oral, Low-Dose IFNs in Species of Veterinary Interest: Back to the Future Sara Frazzini 1 , Federica Riva 2,* and Massimo Amadori 3 1 Gastroenterology and Endoscopy Unit, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy; [email protected] 2 Dipartimento di Medicina Veterinaria, Università degli Studi di Milano, 26900 Lodi, Italy 3 Rete Nazionale di Immunologia Veterinaria, 25125 Brescia, Italy; [email protected] * Correspondence: [email protected]; Tel.: +39-0250334519 Abstract: Cytokines are important molecules that orchestrate the immune response. Given their role, cytokines have been explored as drugs in immunotherapy in the fight against different pathological conditions such as bacterial and viral infections, autoimmune diseases, transplantation and cancer. One of the problems related to their administration consists in the definition of the correct dose to avoid severe side effects. In the 70s and 80s different studies demonstrated the efficacy of cytokines in veterinary medicine, but soon the investigations were abandoned in favor of more profitable drugs such as antibiotics. Recently, the World Health Organization has deeply discouraged the use of antibiotics in order to reduce the spread of multi-drug resistant microorganisms. In this respect, the use of cytokines to prevent or ameliorate infectious diseases has been highlighted, and several studies show the potential of their use in therapy and prophylaxis also in the veterinary field. In this review we aim to review the principles of cytokine treatments, mainly IFNs, and to update the experiences encountered in animals. Keywords: veterinary immunotherapy; cytokines; IFN; low dose treatment; oral treatment Citation: Frazzini, S.; Riva, F.; Amadori, M.
  • 1-(4-Amino-Cyclohexyl)

    1-(4-Amino-Cyclohexyl)

    (19) & (11) EP 1 598 339 B1 (12) EUROPEAN PATENT SPECIFICATION (45) Date of publication and mention (51) Int Cl.: of the grant of the patent: C07D 211/04 (2006.01) C07D 211/06 (2006.01) 24.06.2009 Bulletin 2009/26 C07D 235/24 (2006.01) C07D 413/04 (2006.01) C07D 235/26 (2006.01) C07D 401/04 (2006.01) (2006.01) (2006.01) (21) Application number: 05014116.7 C07D 401/06 C07D 403/04 C07D 403/06 (2006.01) A61K 31/44 (2006.01) A61K 31/48 (2006.01) A61K 31/415 (2006.01) (22) Date of filing: 18.04.2002 A61K 31/445 (2006.01) A61P 25/04 (2006.01) (54) 1-(4-AMINO-CYCLOHEXYL)-1,3-DIHYDRO-2H-BENZIMIDAZOLE-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS NOCICEPTIN ANALOGS AND ORL1 LIGANDS FOR THE TREATMENT OF PAIN 1-(4-AMINO-CYCLOHEXYL)-1,3-DIHYDRO-2H-BENZIMIDAZOLE-2-ON DERIVATE UND VERWANDTE VERBINDUNGEN ALS NOCICEPTIN ANALOGE UND ORL1 LIGANDEN ZUR BEHANDLUNG VON SCHMERZ DERIVÉS DE LA 1-(4-AMINO-CYCLOHEXYL)-1,3-DIHYDRO-2H-BENZIMIDAZOLE-2-ONE ET COMPOSÉS SIMILAIRES POUR L’UTILISATION COMME ANALOGUES DU NOCICEPTIN ET LIGANDES DU ORL1 POUR LE TRAITEMENT DE LA DOULEUR (84) Designated Contracting States: • Victory, Sam AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU Oak Ridge, NC 27310 (US) MC NL PT SE TR • Whitehead, John Designated Extension States: Newtown, PA 18940 (US) AL LT LV MK RO SI (74) Representative: Maiwald, Walter (30) Priority: 18.04.2001 US 284666 P Maiwald Patentanwalts GmbH 18.04.2001 US 284667 P Elisenhof 18.04.2001 US 284668 P Elisenstrasse 3 18.04.2001 US 284669 P 80335 München (DE) (43) Date of publication of application: (56) References cited: 23.11.2005 Bulletin 2005/47 EP-A- 0 636 614 EP-A- 0 990 653 EP-A- 1 142 587 WO-A-00/06545 (62) Document number(s) of the earlier application(s) in WO-A-00/08013 WO-A-01/05770 accordance with Art.
  • Afelimomab (Rinn) Ic Medicines Under the Following Names: Adonis V

    Afelimomab (Rinn) Ic Medicines Under the Following Names: Adonis V

    2248 Supplementary Drugs and Other Substances Adiphenine Hydrochloride (USAN, rINNM) Adrenalone Hydrochloride (pINNM) ⊗ Uses. The use of aesculus has been reviewed;1,2 although there is some evidence suggesting benefit in chronic venous insuffi- Adiphénine, Chlorhydrate d’; Adiphenini Hydrochloridum; Adrénalone, Chlorhydrate d’; Adrenaloni Hydrochloridum; ciency, more rigorous studies are needed.2 Cloridrato de Adifenina; Hidrocloruro de adifenina; NSC- Adrenalonu chlorowodorek; Hidrocloruro de adrenalona. 1. Sirtori CR. Aescin: pharmacology, pharmacokinetics and thera- 129224; Spasmolytine. Адреналона Гидрохлорид peutic profile. Pharmacol Res 2001; 44: 183–93. Адифенина Гидрохлорид C H NO ,HCl = 217.6. 2. Pittler MH, Ernst E. Horse chestnut seed extract for chronic ve- 9 11 3 nous insufficiency. Available in The Cochrane Database of Sys- C20H25NO2,HCl = 347.9. CAS — 62-13-5. tematic Reviews; Issue 1. Chichester: John Wiley; 2006 (ac- CAS — 50-42-0. ATC — A01AD06; B02BC05. cessed 31/03/06). ATC Vet — QA01AD06; QB02BC05. Profile Preparations Adiphenine and adiphenine hydrochloride have been used as Profile Proprietary Preparations (details are given in Part 3) antispasmodics. Adrenalone hydrochloride is used as a local haemostatic and va- Arg.: Grafic Retard; Herbaccion Venotonico; Nadem; Venastat; Venostasin; soconstrictor. It has also been used with adrenaline in eye drops Austria: Aesculaforce; Provenen; Reparil; Venosin; Venostasin; Belg.: Preparations for glaucoma. Reparil; Veinofytol; Venoplant; Braz.: Phytovein; Reparil; Varilise;
  • Modafinil and Modafinil Analogues: Free Radical Mechanism of the Eugeroic and Cognitive Enhancment Effect Clifford Fong

    Modafinil and Modafinil Analogues: Free Radical Mechanism of the Eugeroic and Cognitive Enhancment Effect Clifford Fong

    Modafinil and modafinil analogues: free radical mechanism of the eugeroic and cognitive enhancment effect Clifford Fong To cite this version: Clifford Fong. Modafinil and modafinil analogues: free radical mechanism of the eugeroic and cognitive enhancment effect. [Research Report] Eigenenergy. 2018. hal-01933737 HAL Id: hal-01933737 https://hal.archives-ouvertes.fr/hal-01933737 Submitted on 24 Nov 2018 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Modafinil and modafinil analogues: free radical mechanism of the eugeroic and cognitive enhancment effect Clifford W. Fong Eigenenergy, Adelaide, South Australia. Keywords: Modafinil, modafinil-like analogues, eugeroic effect, cognitive enhancement, free radicals, quantum mechanics Abbreviations Dopamine DA, dopamine transporter DAT, Dissociative electron transfer or attachment DET, Linear free energy relationship LFER, free energy of water desolvation ΔG desolv,CDS , lipophilicity free energy ΔG lipo,CDS, cavity dispersion solvent structure of the first solvation shell CDS, highest occupied molecular orbital HOMO, lowest unoccupied molecular orbital LUMO, multiple correlation coefficient R 2, the F test of significance, standards errors for the estimate (SEE) and standard errors of the variables SE(ΔG desolCDS ), SE(ΔG lipoCDS ), SE(Dipole Moment), SE (Molecular Volume), transition state TS, reactive oxygen species ROS.
  • )&F1y3x PHARMACEUTICAL APPENDIX to THE

    )&F1y3x PHARMACEUTICAL APPENDIX to THE

    )&f1y3X PHARMACEUTICAL APPENDIX TO THE HARMONIZED TARIFF SCHEDULE )&f1y3X PHARMACEUTICAL APPENDIX TO THE TARIFF SCHEDULE 3 Table 1. This table enumerates products described by International Non-proprietary Names (INN) which shall be entered free of duty under general note 13 to the tariff schedule. The Chemical Abstracts Service (CAS) registry numbers also set forth in this table are included to assist in the identification of the products concerned. For purposes of the tariff schedule, any references to a product enumerated in this table includes such product by whatever name known. Product CAS No. Product CAS No. ABAMECTIN 65195-55-3 ACTODIGIN 36983-69-4 ABANOQUIL 90402-40-7 ADAFENOXATE 82168-26-1 ABCIXIMAB 143653-53-6 ADAMEXINE 54785-02-3 ABECARNIL 111841-85-1 ADAPALENE 106685-40-9 ABITESARTAN 137882-98-5 ADAPROLOL 101479-70-3 ABLUKAST 96566-25-5 ADATANSERIN 127266-56-2 ABUNIDAZOLE 91017-58-2 ADEFOVIR 106941-25-7 ACADESINE 2627-69-2 ADELMIDROL 1675-66-7 ACAMPROSATE 77337-76-9 ADEMETIONINE 17176-17-9 ACAPRAZINE 55485-20-6 ADENOSINE PHOSPHATE 61-19-8 ACARBOSE 56180-94-0 ADIBENDAN 100510-33-6 ACEBROCHOL 514-50-1 ADICILLIN 525-94-0 ACEBURIC ACID 26976-72-7 ADIMOLOL 78459-19-5 ACEBUTOLOL 37517-30-9 ADINAZOLAM 37115-32-5 ACECAINIDE 32795-44-1 ADIPHENINE 64-95-9 ACECARBROMAL 77-66-7 ADIPIODONE 606-17-7 ACECLIDINE 827-61-2 ADITEREN 56066-19-4 ACECLOFENAC 89796-99-6 ADITOPRIM 56066-63-8 ACEDAPSONE 77-46-3 ADOSOPINE 88124-26-9 ACEDIASULFONE SODIUM 127-60-6 ADOZELESIN 110314-48-2 ACEDOBEN 556-08-1 ADRAFINIL 63547-13-7 ACEFLURANOL 80595-73-9 ADRENALONE
  • Infant Antibiotic Exposure Search EMBASE 1. Exp Antibiotic Agent/ 2

    Infant Antibiotic Exposure Search EMBASE 1. Exp Antibiotic Agent/ 2

    Infant Antibiotic Exposure Search EMBASE 1. exp antibiotic agent/ 2. (Acedapsone or Alamethicin or Amdinocillin or Amdinocillin Pivoxil or Amikacin or Aminosalicylic Acid or Amoxicillin or Amoxicillin-Potassium Clavulanate Combination or Amphotericin B or Ampicillin or Anisomycin or Antimycin A or Arsphenamine or Aurodox or Azithromycin or Azlocillin or Aztreonam or Bacitracin or Bacteriocins or Bambermycins or beta-Lactams or Bongkrekic Acid or Brefeldin A or Butirosin Sulfate or Calcimycin or Candicidin or Capreomycin or Carbenicillin or Carfecillin or Cefaclor or Cefadroxil or Cefamandole or Cefatrizine or Cefazolin or Cefixime or Cefmenoxime or Cefmetazole or Cefonicid or Cefoperazone or Cefotaxime or Cefotetan or Cefotiam or Cefoxitin or Cefsulodin or Ceftazidime or Ceftizoxime or Ceftriaxone or Cefuroxime or Cephacetrile or Cephalexin or Cephaloglycin or Cephaloridine or Cephalosporins or Cephalothin or Cephamycins or Cephapirin or Cephradine or Chloramphenicol or Chlortetracycline or Ciprofloxacin or Citrinin or Clarithromycin or Clavulanic Acid or Clavulanic Acids or clindamycin or Clofazimine or Cloxacillin or Colistin or Cyclacillin or Cycloserine or Dactinomycin or Dapsone or Daptomycin or Demeclocycline or Diarylquinolines or Dibekacin or Dicloxacillin or Dihydrostreptomycin Sulfate or Diketopiperazines or Distamycins or Doxycycline or Echinomycin or Edeine or Enoxacin or Enviomycin or Erythromycin or Erythromycin Estolate or Erythromycin Ethylsuccinate or Ethambutol or Ethionamide or Filipin or Floxacillin or Fluoroquinolones
  • NINDS Custom Collection II

    NINDS Custom Collection II

    ACACETIN ACEBUTOLOL HYDROCHLORIDE ACECLIDINE HYDROCHLORIDE ACEMETACIN ACETAMINOPHEN ACETAMINOSALOL ACETANILIDE ACETARSOL ACETAZOLAMIDE ACETOHYDROXAMIC ACID ACETRIAZOIC ACID ACETYL TYROSINE ETHYL ESTER ACETYLCARNITINE ACETYLCHOLINE ACETYLCYSTEINE ACETYLGLUCOSAMINE ACETYLGLUTAMIC ACID ACETYL-L-LEUCINE ACETYLPHENYLALANINE ACETYLSEROTONIN ACETYLTRYPTOPHAN ACEXAMIC ACID ACIVICIN ACLACINOMYCIN A1 ACONITINE ACRIFLAVINIUM HYDROCHLORIDE ACRISORCIN ACTINONIN ACYCLOVIR ADENOSINE PHOSPHATE ADENOSINE ADRENALINE BITARTRATE AESCULIN AJMALINE AKLAVINE HYDROCHLORIDE ALANYL-dl-LEUCINE ALANYL-dl-PHENYLALANINE ALAPROCLATE ALBENDAZOLE ALBUTEROL ALEXIDINE HYDROCHLORIDE ALLANTOIN ALLOPURINOL ALMOTRIPTAN ALOIN ALPRENOLOL ALTRETAMINE ALVERINE CITRATE AMANTADINE HYDROCHLORIDE AMBROXOL HYDROCHLORIDE AMCINONIDE AMIKACIN SULFATE AMILORIDE HYDROCHLORIDE 3-AMINOBENZAMIDE gamma-AMINOBUTYRIC ACID AMINOCAPROIC ACID N- (2-AMINOETHYL)-4-CHLOROBENZAMIDE (RO-16-6491) AMINOGLUTETHIMIDE AMINOHIPPURIC ACID AMINOHYDROXYBUTYRIC ACID AMINOLEVULINIC ACID HYDROCHLORIDE AMINOPHENAZONE 3-AMINOPROPANESULPHONIC ACID AMINOPYRIDINE 9-AMINO-1,2,3,4-TETRAHYDROACRIDINE HYDROCHLORIDE AMINOTHIAZOLE AMIODARONE HYDROCHLORIDE AMIPRILOSE AMITRIPTYLINE HYDROCHLORIDE AMLODIPINE BESYLATE AMODIAQUINE DIHYDROCHLORIDE AMOXEPINE AMOXICILLIN AMPICILLIN SODIUM AMPROLIUM AMRINONE AMYGDALIN ANABASAMINE HYDROCHLORIDE ANABASINE HYDROCHLORIDE ANCITABINE HYDROCHLORIDE ANDROSTERONE SODIUM SULFATE ANIRACETAM ANISINDIONE ANISODAMINE ANISOMYCIN ANTAZOLINE PHOSPHATE ANTHRALIN ANTIMYCIN A (A1 shown) ANTIPYRINE APHYLLIC
  • (12) United States Patent (10) Patent No.: US 6,264,917 B1 Klaveness Et Al

    (12) United States Patent (10) Patent No.: US 6,264,917 B1 Klaveness Et Al

    USOO6264,917B1 (12) United States Patent (10) Patent No.: US 6,264,917 B1 Klaveness et al. (45) Date of Patent: Jul. 24, 2001 (54) TARGETED ULTRASOUND CONTRAST 5,733,572 3/1998 Unger et al.. AGENTS 5,780,010 7/1998 Lanza et al. 5,846,517 12/1998 Unger .................................. 424/9.52 (75) Inventors: Jo Klaveness; Pál Rongved; Dagfinn 5,849,727 12/1998 Porter et al. ......................... 514/156 Lovhaug, all of Oslo (NO) 5,910,300 6/1999 Tournier et al. .................... 424/9.34 FOREIGN PATENT DOCUMENTS (73) Assignee: Nycomed Imaging AS, Oslo (NO) 2 145 SOS 4/1994 (CA). (*) Notice: Subject to any disclaimer, the term of this 19 626 530 1/1998 (DE). patent is extended or adjusted under 35 O 727 225 8/1996 (EP). U.S.C. 154(b) by 0 days. WO91/15244 10/1991 (WO). WO 93/20802 10/1993 (WO). WO 94/07539 4/1994 (WO). (21) Appl. No.: 08/958,993 WO 94/28873 12/1994 (WO). WO 94/28874 12/1994 (WO). (22) Filed: Oct. 28, 1997 WO95/03356 2/1995 (WO). WO95/03357 2/1995 (WO). Related U.S. Application Data WO95/07072 3/1995 (WO). (60) Provisional application No. 60/049.264, filed on Jun. 7, WO95/15118 6/1995 (WO). 1997, provisional application No. 60/049,265, filed on Jun. WO 96/39149 12/1996 (WO). 7, 1997, and provisional application No. 60/049.268, filed WO 96/40277 12/1996 (WO). on Jun. 7, 1997. WO 96/40285 12/1996 (WO). (30) Foreign Application Priority Data WO 96/41647 12/1996 (WO).
  • Pharmacology on Your Palms CLASSIFICATION of the DRUGS

    Pharmacology on Your Palms CLASSIFICATION of the DRUGS

    Pharmacology on your palms CLASSIFICATION OF THE DRUGS DRUGS FROM DRUGS AFFECTING THE ORGANS CHEMOTHERAPEUTIC DIFFERENT DRUGS AFFECTING THE NERVOUS SYSTEM AND TISSUES DRUGS PHARMACOLOGICAL GROUPS Drugs affecting peripheral Antitumor drugs Drugs affecting the cardiovascular Antimicrobial, antiviral, Drugs affecting the nervous system Antiallergic drugs system antiparasitic drugs central nervous system Drugs affecting the sensory Antidotes nerve endings Cardiac glycosides Antibiotics CNS DEPRESSANTS (AFFECTING THE Antihypertensive drugs Sulfonamides Analgesics (opioid, AFFERENT INNERVATION) Antianginal drugs Antituberculous drugs analgesics-antipyretics, Antiarrhythmic drugs Antihelminthic drugs NSAIDs) Local anaesthetics Antihyperlipidemic drugs Antifungal drugs Sedative and hypnotic Coating drugs Spasmolytics Antiviral drugs drugs Adsorbents Drugs affecting the excretory system Antimalarial drugs Tranquilizers Astringents Diuretics Antisyphilitic drugs Neuroleptics Expectorants Drugs affecting the hemopoietic system Antiseptics Anticonvulsants Irritant drugs Drugs affecting blood coagulation Disinfectants Antiparkinsonian drugs Drugs affecting peripheral Drugs affecting erythro- and leukopoiesis General anaesthetics neurotransmitter processes Drugs affecting the digestive system CNS STIMULANTS (AFFECTING THE Anorectic drugs Psychomotor stimulants EFFERENT PART OF THE Bitter stuffs. Drugs for replacement therapy Analeptics NERVOUS SYSTEM) Antiacid drugs Antidepressants Direct-acting-cholinomimetics Antiulcer drugs Nootropics (Cognitive