ANNUAL REPORT

2008

Northeastern Section

American Chemical Society

Local Section Name: Northeastern Section URL for Total Report: http://www.nesacs.org

1 Dr. Marietta Schwartz Chair 2008 Northeastern Section, ACS

2 TABLE OF CONTENTS

PART I - QUESTIONNAIRE

Annual Report Questionnaire...... 6

PART II: ANNUAL NARRATIVE REPORT

Activities: Activity 1 - Connections to Chemistry...... 15 Activity 2 - Northeastern Student Chemistry Research Conference...... 15 Activity 3 - National Chemistry Week Activities...... 15 Activity 4 - Fifth Annual Northeast Student Career Fair ...... 16 Activity 5 - Medicinal Chemistry Group Meetings & Symposia...... 16 Activity 6 - Fourth Annual NESACS Golf Tournament ...... 16 Activity 7 - Summerthing 2008...... 16 Activity 8 - 2008 German-NSYCC Exchange...... 17 Activity 9 - NESACS Celebrates Earth Day...... 17 Activity 10-Advances in Chemical Sciences Symposium...... 18 Summary...... 18 2008 Goal Attainment 2008 Local Section Goals and Assessment...... 20 2008 Chair’s Goals and Assessment ...... 21 2009 Goals...... 21

PART II - APPENDICES 1-5

APPENDIX 1 - SUPPORTING DOCUMENTS FOR ACTIVITIES

Supporting Documents for Activities...... 24 Activity 1 - Connections to Chemistry...... 24 Activity 2 - Northeastern Student Chemistry Research Conference...... 26 Activity 3 - National Chemistry Week Activities...... 29 Activity 4 - Fifth Annual Northeast Student Career Fair ...... 30 Activity 5 - Medicinal Chemistry Group Meetings & Symposia...... 32 Activity 6 - Fourth Annual NESACS Golf Tournament ...... 35 Activity 7 - Summerthing 2008...... 37 Activity 8 - 2008 German-NSYCC Exchange...... 38 Activity 9 - NESACS Celebrates Earth Day...... 39 Activity 10-Advances in Chemical Sciences Symposium...... 40

APPENDIX 2 - BUDGETS AND LONG-RANGE PLAN

2-A: Budget for 2008...... 42 Budget for 2009...... 45 2-B: Long-Range Plan...... 47

APPENDIX 3 - MEMBERSHIP SURVEYS AND 2008 NEWSLETTER

3-A: Membership Survey Conducted in 2008 - No survey conducted in 2008...... 52 3-B: 2008 Newsletter...... 52 May 2008 issue of The Nucleus uploaded to ACS online report (S.O.L.A.R.)

APPENDIX 4 - PUBLIC RELATIONS PLAN - TALKS TO PUBLIC - NEWSPAPER CLIPPINGS

4-A: Public Relations Plan - No plan prepared for 2008...... 53 4-B: Talks to Public ...... 54 4-C: Press Releases: None available

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APPENDIX 5 - AS NEEDED BY SECTION: NESACS REPORTS

Officers, Councilors, Directors, and Committee Chairs 2008 ...... 60 Calendar of Activities 2008 ...... 66 Reports: Archivist...... 69 Awards Committee ...... 69 Awards Presented by the Northeastern Section ...... 78 Awards & Honors Received by NESACS Members from Other Organizations ...... 79 Brauner, Phyllis A. - Memorial Lecture...... 82 Constitution & Bylaws...... 84 Continuing Education Committee ...... 84 Earth Day...... 86 Education Committee ...... 86 Education Committee / High School Subcommittee...... 95 Esselen Award Committee...... 108 Fund-raising Committee...... 115 Government Relations Committee ...... 119 Local Arrangements Committee...... 120 Medicinal Chemistry Group...... 121 Membership Committee ...... 128 National Chemistry Week Committee...... 130 Nominating Committee...... 132 Norris Award Committee ...... 133 Northeast Regional Meeting (NERM) ...... 141 Professional Relations Committee ...... 144 Program Committee / Chair-Elect...... 145 Publications, Board of...... 148 Richards Medal Committee...... 149 Summerthing 2008 ...... 153 Treasurer and Auditor...... 154 Trustees, Board of ...... 156 Younger Chemists Committee...... 157

APPENDIX 5-A; SPECIAL PROGRAMS / web pages

NSYCC: NSCRC - German Exchange Program - YCC Career Fair...... 163 Undergraduate Research Symposium at Bridgewater State College - BSC web site...... 164

APPENDIX 6 - YOUNGER CHEMISTS COMMITTEE

Report of the Younger Chemists Committee SEE APPENDIX 5 FOR YCC REPORTS...... 167

PART III - ANNUAL FINANCIAL REPORT (uploaded into SOLAR form)

Part A: Statement of Revenues and Expenses Operating Fund...... 169 Part B: Balance Sheet as of 12/31/08 ...... 170

PART IV - SELF-NOMINATIONS FOR CHEMLUMINARY AWARDS

Outstanding Performance by Local Sections (M. Schwartz)...... 172 Outstanding Event for the General Public Using the Yearly Theme ...... 174 Outstanding Event for a Specific Audience - NCW (C. Jaworek-Lopes)...... 176 Outstanding On-going NCW Event (R. Tanner) ...... 177

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ANNUAL REPORT Northeastern Section, ACS

PART I

QUESTIONNAIRE

http://www.nesacs.org

5

American Chemical Society

Form: Part I - Annual Report Questionnaire REQUIRED Organization: Northeastern Year: 2008

****Important Notice Please Read****

Web Posting of Annual Reports

Our Section would like to have Parts I and II (if applicable) posted on the Local Section Activities Committee website.

1. TOP ACTIVITIES

Please list the titles of your top activities (Rank order) and indicate if the activity was new in 2008. Check if new in 2008 Title of Activity Connections to Chemistry 1. Northeastern Student Chem. Research Conf 2. National Chemistry Week Activities 3. 5th Annual Northeast Student Career Fair 4. Medicinal Chem Group Meetings & Symposia 5. 4th Annual NESACS Golf Tournament 6. Summerthing 2008 7. x 2008 German-NSYCC Exchange 8. NESACS Celebrates Earth Day 9. x Advances in Chem Sciences Symposium 10.

2. SECTION ADMINISTRATION

EXECUTIVE COMMITTEE

10 2.1 How many times did the executive committee meet during 2008? 59 2.2 How many members are on the executive committee? 9 2.3 How many section meetings were held in 2008? 60 2.4 On average, how many members attend a regular section meetings? COUNCILORS

6 What percentage of the section's Councilors were in official attendance at the ACS spring Council 100 2.5 meeting? % What percentage of the section’s Councilors were in official attendance at the ACS fall Council 100 2.6 meeting? % 2.7 How do Councilors report to the section about national ACS matters? (check all that apply) at a section meeting X at an executive committee meeting X in thenewsletter X on the local section website COMMITTEES 2.8 Specify active committees having two or more members. Please indicate the chair's name where appropriate. Awards Mentoring Chair: Michael Dube Chair:

Budgets/Finance Minority Affairs Chair: James U. Piper Chair:

Career Assistance/Employment Newsletter/Publication Chair: Mukund Chorghade Chair: Mary Mahaney

Chemistry Olympiad Nominations Chair: Stephen Lantos Chair: Mukund Chorghade

Community Activities (e.g. National Chemistry Week or Chemists Celebrate Earth Day, etc.) Professional Relations Chair: C. Jaworek-Lopes Chair: Mukund Chorghade

Continuing Education Project SEED Chair: Alfred Viola Chair: Patricia Mabrouk

Education Public Relations Chair: Ruth Tanner Chair:

Environmental Senior Chemists Chair: Chair:

Environmental Health & Safety/ Chemical Hygiene Women Chemists Chair: Chair: Patricia Mabrouk

Government Affairs Younger Chemists Chair: Doris Lewis Chair: L.Dafik & L. Johnson

Other: Fund-raising Industry Relations Chair: Chair: Dorothy Phillips

Other: Constitution & Bylaws Long-Range Planning Chair: Marietta Schwartz Chair: Catherine Costello

Other: Local Arrangements Membership/Member Retention Chair: Michaeline Chen Chair: Mary Burgess

Other: Programs

7 Chair: E. Joseph Billo

SUBSECTIONS

1 2.9 How many subsections are active in the section? 3 2.10 How many subsection meetings were held in 2008? TOPICAL GROUPS

0 2.11 How many topical groups are active in the section?

2.12 How many topical group meetings were held in 2008? OPERATIONS AND PLANNING (check all that apply) 2.13 x The section prepared a budget for 2008 (Please include a copy in Part II Appendix 2) 2.14 x The section prepared a budget for 2009 (Please include a copy in Part II, Appendix 2) 2.15 x The section prepared a long-range plan (Please include a copy in Part II, Appendix 2) The section maintains and uses a current job manual prepared by the section as a guide for officers and 2.16 x committees. The section conducted a membership survey in 2008 to determine member's interests and needs (Please 2.17 include a copy in Part II, Appendix 3) 2.18 x A section representative attended the ACS Leaders Conference (Local Section Leaders Track) in 2008. 2.19 The section has a succession plan. SECTION COMMUNICATION

10 2.20 How many newsletters were published in 2008? 2.21 x One copy of a newsletter is included in Appendix 3.

45 2.22 How many meeting notices were published in 2008? a. URL: http://www.nesacs.org 2.23 x The section has an active website. b. Webmaster Name: David Cunningham

c. email: [email protected]

2.24 x The section used electronic communication. 2.25 x The section posted its 2007 Annual Report on its website. SECTION ELECTIONS 2.26 X The section conducted a 2008 officer election Please identify vendor or software used. 2.27 The section conducted its 2008 elections electronically. 2.28 The section revised its bylaws to allow electronic elections

462 2.29 How many members voted in the 2008 officer election? How many 2008 elected officials, councilors and committee 2.30 chairs:

9 a. have held other elected positions in the local section 19 b. have held other appointed positions in the local section 8 c. presently hold more than one elected office 2 d. are in their first two years of service

2.31 For each election that was held in 2008 please give the number of members that ran for:

2 a. Chair-elect 8 0 b. Secretary 1 c. Treasurer d. Other (not including councilor) Director-at-Large 3

2.32 For the positions of Councilor and Alternate Councilor, did your No local section vote for a single list of Councilor/Alternate Councilors candidates with the highest vote getters being elected as Councilor and those with the next highest vote counts being elected Alternate X Yes Councilor?

5 2.33 How many total Councilor positions were available for 2008? 5 2.34 How many total Alternate Councilor positions were available for 2008? 5 2.35 How many Councilor positions were filled in 2008?

5 2.36 How many total Alternate Councilor position were filled in 2008? 12 2.37 How many candidates were on the 2008 ballot for the available Councilor positions? How many candidates were on the 2008 ballot for the available Alternate Councilor 12 2.38 positions? 12 2.39 What was the total number of candidates for Councilor and Alternate Councilor in 2008? SECTION AWARDS (check all that apply) The section submitted a nomination for the ACS Regional Award in High School Chemistry Teaching 2.40 during 2008. The section submitted a nomination for the Stanley C. Israel Regional Award for Advancing Diversity in 2.41 the Chemical Sciences. The section gave awards or a Salutes to Excellence to: 2.4 2 X Primary school students (K-6) 2.4 3 X Secondary school students (7-12) 2.4 4 X College students 2.4 5 Primary school teachers (K-6) 2.4 6 X Secondary school teachers (7-12) 2.4 7 X College teachers 2.4 8 X Members of the local section for service 2.4 9 X Outstanding chemists, regardless of section affiliation

2.5 The section or local company encouraged and/or submitted a nomination for the ACS Regional Industrial 0 Innovation Awards. SECTION AFFILIATES How many paid section affiliates excluding students (teachers, technicians, others) are there in 18 2.51 the section? 2.52 Section has supported an existing Technician Affiliate Group (TAG)during 2008. 9 2.53 Section has promoted the formation of a Technician Affiliate Group during 2008. REGIONAL MEETINGS 2.54 x Does your local section have a representative to your Regional Board/Steering Committee? 2.55 x Does your section participate in the Regional Chmemjobs Employment Center? VOLUNTEERS

2.56 Please indicate the approximate number of active volunteers in your local section. (Volunteer is defined as a member who helps plan or organizes a meeting or activity, 135 serves on a committee, or is an elected official including Councilor and Alternate Councilor.) 44 a. How many of these volunteers were new in 2008?

Please indicate all the ways that you recognize 2.57 volunteers:

Certificates X Gifts

x Awards Letter to volunteer

Letter to volunteer's supervisor X Recognition at an event Other: No formal recognition program

2.58 How does your local section identify future leaders and get them into the leadership pipeline?

x Self-Nominations Solicitation or advertising x

x Identify active committee members Formal leadership training

x Outreach to new members Arm-Twisting x Other:

2.59 Aside from the Chair-Elect becoming Chair, does your local section have a long-term plan for developing new leaders and/or volunteers? Yes X No 2.60 Does your local section support travel of members (other than councilors) to:

x National meetings Regional meetings x

x Leaders Conferences Other

3 - 8 Connecting Chemistry and the Community

3. COMMUNITY BUILDING (check all that apply) 3.1 x Industrial members are active in the section's governance. The section communicated with non-ACS members working in industry and local companies about meetings 3.2 x and programs. 3.3 x Local companies have financially-sponsored an activity or donated money to the section. 3.4 Industrial members (M), local companies (C), and/or non-members employed in industry (N) participated in these section programs or activities: M C N x x x Meeting at industrial site/plant tour x x x Local Section Award/Recognition program

x Membership drive for new members x x x Industrial speaker/Industrially-focused topic x x x National Chemistry Week, Chemists Celebrate Earth Day or other community outreach activity 10 x x x Career development activities x x x Student or younger chemist activities

The section is affiliated with other technical or scientific societies or 3.5 consortia. a. The section affiliated with:

(name of technical organization)

This affiliation was approved by ACS council in what year.

Please indicate groups that your section held 3.6 joint event(s) with:

Local Section Boy/Girl Scouts

Another Professional Community Group Society NOBCChE Underrepresented Minority Community Group X Other 4. MENTORING AND LEADERSHIP (check all that apply) 4.1 x The section provided services for pre-college students. 4.2 x The section provided speakers for student affiliates chapter meetings. 4.3 x The section organized tours of local industries for student affiliates.

4.4 The section offered financial support for student affiliates chapter activities. The section offered financial support to students attending regional or national meetings (undergraduate 4.5 x and/or graduate).

4.6 The section appointed a member as student affiliates chapter liaison. The section members served as non-faculty professional advisers or contacts for students and young 4.7 x chemists.

4.8 The section provided students with free subscriptions to journals. 4.9 x The section invited student affiliates to attend regular section meetings.

4.10 The section sponsored a teacher affiliate group to engage students in ACS. 4.11 The section involved student affiliates in community outreach activities x (e.g. National Chemistry Week and/or Chemists Celebrate Earth Day, etc.). 4.12 x The section distributed career literature to students or to colleges and universities. 4.13 The section developed and maintained a networking directory. 5. PROFESSIONAL DEVELOPMENT (check all that apply) 5.1 X The section published articles on employment services in its newsletter or web site X The section sponsored local employment services (e.g., free ads in section newsletter or website, job 5.2 counseling, employment clearinghouse X A section representative attended a Local Section Career Program offered by the National ACS (if 5.3 available) during 2008 X The section referred individuals to the national ACS Department of Career Management and 5.4 Development 5.5 X The section maintained a job line for career opportunities available within the local section 5.6 X The section hosted an ACS Short Course

15 5.7 How many local section career programs or activities were conducted in 2008? 15

11 5 5 a. How many career programs were new in 2008? 5.8 X The section offered career counseling literature 5.9 X The section maintains a list (and contact information) of local organizations networking directory) that employ chemical professionals? 5.1 0 X The section have a Career Coordinator? 6. CONTINUING EDUCATION (check all that apply) 6.1 The section organized a regional meeting.

An ACS Technical Division was involved. 6.2 X The Section organized a symposium

An ACS Technical Division was involved.

6.3 The organized a Meeting-in-Miniature.

An ACS Technical Division was involved. 6.4 X The section organized an undergraduate research symposium

An ACS Technical Division was involved.

6.5 The section organized a meeting that was co-sponsored by an ACS Technical Division.

6.6 x The section has topical groups in interdisciplinary areas. 6.7 x The section has sponsored meetings with an interdisciplinary focus. The section offered activities such as symposia, seminars, or sponsored student activities on environmental 6.8 x issues. The section offered specifically tailored symposia, seminars, or sponsored activities for industrial chemical 6.9 x professionals. 7. PUBLIC OUTREACH (check all that apply)

The section provided assistance to K-12 schools by: 7.1 Providing judges for area science fair(s) 7.2 Sponsoring awards at area science fair(s) 7.3 x Participate in US National Chemistry Olympiad 7.4 x Presenting career programs and/or distributing career literature to students or schools Sponsoring or organizing student competitions (e.g., chemistry examinations, ChemBowls, poster 7.5 x competitions) 7.6 x Presenting Chemical Demonstrations 7.7 x Participating in National US Chemistry Olympiad

7.8 Members making visits to K-8 classrooms. 7.9 x Members making visits to 9-12 classrooms

The section encourages participation and leadership in all aspects of the chemical sciences by women (W), underrepresented groups (G), and persons with disabilities (D). (check all that apply) W G D The section conducted hands-on science activities in elementary and/or middle school 7.10 classrooms. 7.11 x x x The section sponsored hands-on science activities in underserved communities. 7.12 x x x The section provided summer research opportunities.

7.13 The section developed science career fairs at high schools or colleges that have high female, underrepresented minority or disabled populations.

12 7.14 The section organized summer science camps. 7.15 x x x The section sponsored contests or awards. 7.16 x x x The section maintained employment services.

7.17 x x x The section leadership (elected or appointed) includes underrepresented groups. 7.18 x x x The section sponsored community outreach activities. 7.19 x x x Section members mentored students or colleagues.

7.20 The section maintained an experts roster and provided it to local media.

7.21 The section created or updated a media list.

7.22 The section prepared a public relations plan and included a copy of this plan in Appendix 4. How many times were section activities promoted to the local media (press releases, op-eds,

7.23 advisories, etc.)? 7.24 The section used an ACS film, videotape, or other ACS visual-aid resource at a public event.

61 7.25 How many talks were given by section members to the public in 2008?

7.26 The section participated in, or conducted the following community activities: X National Chemistry Week X Chemists Celebrate Earth Day Other:

7.27 The number of community outreach events conducted during National Chemistry Week. 6

7.28 The number of community outreach activities conducted during Chemists Celebrate Earth Day. 2

7.29 x The section conducted teacher workshops. 7.30 x The section invited teachers to attend section meetings. 7.31 x The section provided teachers with free subscriptions to magazines or journals. 7.32 x The section involved teachers in section program planning. 7.33 x The section participated in Project SEED 7.34 x The section provided a forum to address educational issues. 7.35 x The section conducted a Science Cafe(s) in 2008.

8. ADVOCACY (check all that apply) 8.1 x The section has a government affairs committee that has regular activities or meetings. 8.2 x The section actively encourages members to join and participated in ACS' Legislative Action Network. Section informed its members on legislative issues and events through newsletter articles, website, or other 8.3 x communication method. The section has made efforts to communicate ACS public policy positions with elected officials or policymakers (such as invitations to local section meetings, visits to offices of elected officials/policymakers, 8.4 x etc.) The section organized or participated in a special government relations event (state capitol day, science town 8.5 x meeting, legislative hearing, public policy forum, etc.). 8.6 x Section member(s) held an office or key position in local, state or federal government in 2008.

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ANNUAL REPORT Northeastern Section, ACS

14

PART II

ANNUAL NARRATIVE REPORT

http://www.nesacs.org

Part II - Annual Narrative Report

Activity 1 - Connections to Chemistry

1. 2008 Connections to Chemistry program was held at Burlington High School. The Northeastern Section of the American Chemical Society (NESACS) and the Education Committee of the Northeastern Section invite high school chemistry teachers to a program at Burlington High School (Burlington, MA) on Thursday, October 16th, 3:30 – 8:00 PM. This program will help connect high school teachers with the numerous education resources that are available from the American Chemical Society. Four simultaneous hands-on workshops will illustrate these resources: • Activities in chemistry (and math) that pave the road to becoming a pharmacist, a career that links the chemical and health sciences in a world of miracle drugs. • Laboratory activities, experiments, and tools in forensics to process the crime scene from a real CSI Lab; • A program for the National Chemistry Week theme, Having a Ball with Chemistry, using chemistry, balls such as superballs and baseballs, and high speed videos to explain why balls bounce (or travel) and how high (or how far); • A computer workshop with programs from the Journal of Chemical Education(JCE) such as Chemistry Comes Alive, the JCE Classroom Activities on CD-ROM, and the ChemEd and National Science Digital Libraries.

Activity 2 - Northeastern Student Chemistry Research Conference

15 2. Northeastern Student Chemistry Research Conference, held April 19, 2008. An opportunity for undergraduate, graduate, and postdoctoral researchers to present their research. Northeastern Section Younger Chemists Committee (NSYCC) and its local Tufts YCC organized the tenth annual Northeast Student Chemist Research Conference on Saturday April 19th at the Chemistry Department of Tufts University. The keynote speaker was Professor Stuart L. Schreiber from the Broad Institute with a lecture titled “Small-molecule Probe and Drug Discovery”. The one day conference consisted of oral presentations given by the younger chemists from the Northeastern region, followed by a poster session where participants discussed their research with their peers and were judged by a NSYCC judging committee.

Activity 3 - National Chemistry Week

3. National Chemistry Week 2008 (October 18-25). The Northeastern Section of the American Chemical Society held several events as part of NCW 2008. The Section held two events for the general public. At both of these events, a number of hands-on activities and demonstrations related to the yearly theme were tried by visitors to the Boston Children’s Museum and the Museum of Science-Boston (MoS-Boston). More than 900 individuals participated in these events. Dr. Bassam Shakhashiri presented two lecture demonstrations as part of the Phyllis A. Brauner Memorial Lectures at the MoS-Boston. The Section partnered with the MoS for our second NCW High School Science Series event. Almost 600 students attended this event. This more than doubled the number of students we reached in 2007!! These students participated in a number of hands-on activities and demonstrations related to the yearly theme. In addition, the students attended a lecture-demonstration given by David Sittenfeld, MoS-Boston, and Patrick Drane, Lowell Baseball Institute regarding materials used in sports. Children (K-12) were able to participate in the poster competition and our two sports-related puzzle competitions. Finally, a local daycare, elementary school, and Emmanuel College all participated in a sneaker recycling event. More than 100 pairs of sneakers will be brought to the Wrentham Outlets (an official Nike drop-off location). Strem Chemicals and Creagen Biosciences, Inc. donated funds to defray the costs associated with NCW 2008.

Activity 4 - Fifth Annual Northeast Student Career Fair

4. Fifth Annual Northeast Student Career Fair, held April 24, 2008. ACS Career Services workshops on resume writing and interviewing skills were performed on-site. There was also a job fair – attendees had the opportunity to meet with representatives from companies in the Northeast about employment opportunities. A related activity was the publication of a four-part series on “Interviewing in the Bio- Pharma Industry”, written by Megan Driscoll, President, PharmLogics Recruiting, in The Nucleus.

Activity 5 - Medicinal Chemistry Group Meetings

5. Medicinal Chemistry meetings – The active participation of the Medicinal Chemistry group in NESACS program planning continued, with three very successful symposia held during the year. Topic included: May (Cost, Speed, and Quality; Emerging Opportunities for Drug Discovery in Asia), September (New Developments in Anti-Infective Research) and December (New Technologies for Drug Discovery). These were all-day events, with many small sessions on various topics related to the overall theme of the day, a keynote speaker, and a dinner. The symposia were supported by local pharmaceutical companies and more than 400 scientists attended in total.

Activity 6 - Fourth Annual NESACS Golf Tournament

16 6. The fourth annual NESACS golf tournament was held on June 25, 2008 at Butternut Farm golf course in Stow, MA (www.butternutfarm.com). It was a perfect day for golf, sunny with a moderate temperature. This year a total of 74 golfers participated in a shotgun scramble. This annual event is a great venue for networking and players came from as far as South Carolina and Wisconsin to participate. The tournament began at 1 PM and was followed by a BBQ dinner and awards ceremony.

Activity 7 - Summerthing 2008

7. Summerthing 2008 – Futures at Fenway, Saturday, August 9, 2008. 40 NESACS members and their families attended a doubleheader at Fenway Park. Boston's Triple-A affiliate, the Pawtucket Red Sox, were joined by the Lowell Spinners, the Red Sox' short-season Single-A affiliate. Lowell faced off against the Hudson Valley Renegades (Tampa Bay Organization) in the inaugural game at 12:05 p.m. while Pawtucket battled the Charlotte Knights (Chicago White Sox Organization) in the second game of the doubleheader. Both Boston affiliates were victorious, with the Lowell Spinners going into extra innings before finally coming up with a run in the 12th inning to prevail. A good time was had by all!

Activity 8 - 2008 German-NSYCC Exchange

8. 2008 German-NSYCC Exchange: The German Chemical Society (Gesellschaft Deutscher Chemiker, GDCh), and its Young Chemists Forum (Jung-Chemikerforum, JCF), welcomed to Germany 12 representatives of the NESACS Younger Chemists Committee (YCC) who had been selected by the German Exchange program steering committee. The visit was the eighth annual exchange program between the NESACS-YCC and GDCh-JCF, highlighting the close connection between the NESACS and the GDCh. The weeklong program began on Wednesday, March 26th, with a day in Rostock and a tour of Rostock University. On Thursday Wendy Iskenderian (MIT) spoke in Frühjahrssymposium about her research. At the end of the day, a poster session was held where the American graduate and undergraduate students displayed their research posters and discussed their scientific progress. In addition, on Friday two students, Brett Fors (MIT) and Raymond Moellering (Harvard University) contributed oral presentations while the rest of the American group discussed their posters. At the end of the day, Frühjahrssymposium hosted a dinner coupled with a social evening where the American contingent had the opportunity to network with their German peers. On Saturday morning, Patrick Cappillino (Boston University) gave an oral presentation and received the third place award for best oral presentation. In addition, Shuyu Wang (Harvard University) was awarded a prize for best poster presentation. In addition to the scientific talks, the program included a four-day stay in Hamburg, where students had the chance to visit Hamburg University and local laboratories such as Dow Chemical. At the end of the week, Dr. Kurt Begitt, Deputy Executive Director and Director of Education and Professional Affairs of the GDCh accompanied by representatives of the Young Chemists Forum (Jung-Chemikerforum, JCF) hosted a farewell dinner in honor of the American delegation.

Activity 9 - NESACS Celebrates Earth Day

9. NESACS Celebrates Earth Day. On April 22, 2008, NESACS partnered with the Massachusetts Bays Estuary Association (MBEA) and the Malden High School Chemistry Club for a daylong event at the Boston Children’s Museum. More than 2000 individuals visited the museum that day. The MBEA provided an Enviroscape Model and demonstrated how pollutants from our homes ultimately end up in our water supply. Children used spray bottles to simulate rain and wash away the waste products (food coloring and spices). In addition, the MBEA provided water samples from two Massachusetts bays. The 17 Malden High School Chemistry Club showed visitors to the museum how to colorimetrically test for pH, water hardness, nitrates, iron, and phosphates in these water samples. In addition, visitors to the museum could test the pH of common household items such as soda and orange juice. Finally, the Malden High School Chemistry Club demonstrated water hardness by adding detergent to samples of hard water and soft water. Children and adults alike were amazed by the difference in lathering ability of these two extremes.

Activity 10 - Advances in Chemical Sciences Symposium

10. Advances in Chemical Sciences Symposium: This was the second annual symposium catering to the needs of the pharmaceutical, biopharmaceutical and biotech industries in the Boston area. The “Advances in Chemical Sciences Symposium” conference, held on April 11, 2008 was a spectacular success. The symposium was a day-long celebration of Chemistry and was held at the Royal Sonesta Hotel in Cambridge, MA. Under the auspices of this conference, eminent scientists from the triad of government and industry and academia delivered plenary lectures. The conference brought together 330+ scientists for a scholarly event focusing on medicinal chemistry, organic synthesis and methodology. This year’s plenary lecturers were Magid Abou-Gharbia (SVP, Wyeth), Mark Goulet, (Executive Director, Merck Research Laboratories), Timothy F. Jamison, (Massachusetts Institute of Technology), John Piwinski (SVP, Schering Plough), Mathew Shair, (Professor, Harvard University), Erik J. Sorensen, (Professor, Princeton University). The topical focus areas – medicinal chemistry, pharmaceutical and organic synthesis – are areas where the chemical enterprise in our area has a well deserved reputation for excellence. A large number of pharmaceutical and biotechnology industry professionals from the metropolitan area joined us for this event, shared ideas and built networks. The response was extremely enthusiastic. A sell out symposium crowd was treated to some exhilarating science from some of the finest practitioners of the discipline. A vendor show drew 16 vendors. The symposium was co- sponsored by the US (East Coast) Section of the RSC, and IUPAC. This helped cement our relationships with our colleagues from other societies. Represented on the organizing committee were scientists from many of the pharma companies in our area. Fundraising netted over $40,000, which was $12,000 above expenses incurred.

Summary – Overall Section Activities

I had the pleasure of chairing the Northeastern Section of the American Chemical Society in 2008. The section had a very successful year again, with a wide variety of programs and events. The majority of the section events were chronicled in the section’s monthly publication, The Nucleus, and information was also posted on the NESACS and NESACS-YCC websites.

Monthly Meetings The Membership Committee sent letters to the more than 900 new members of the Section, inviting them to attend the monthly meetings as the Section’s guest at the dinner preceding the evening presentation. Attendance at the Board of Directors meetings (which immediately precede the monthly meetings) was excellent. Additionally, the Social Hours preceding the monthly dinners and talks were well attended and very enjoyable, also providing good networking opportunities for attendees. The February NESACS meeting was co-sponsored by NOBCChE (the National Organization of Black Chemists and Chemical Engineers), and the September and December meetings were co-sponsored by the NESACS Medicinal

18 Chemistry Group. Ten monthly meetings of the Executive Committee were held, in addition to a meeting dedicated to Long-Range Planning.

Awards In 2008, the Section sponsored and presented the James Flack Norris Award in Physical Organic Chemistry to Prof. Dennis Dougherty (California Institute of Technology) at the Spring 2008 ACS National Meeting in New Orleans, LA. In addition, the Section presented the following awards: the Gustavus John Esselen Award for Chemistry in the Public Interest to Prof. John A. Katzenellenbogen (University of Illinois at Urbana-Champaign); the Theodore William Richards Medal for Conspicuous Achievement in Chemistry to Prof. Robert G. Bergman (University of California-Berkeley); the Henry A. Hill Award for Outstanding Service to the Northeastern Section to Dr. Michael Singer (Sigma- Aldrich);and the James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry to Prof. David K. Gosser (City College of New York), Prof. Jack A. Kampmeier (University of Rochester) and Prof. Pratibha Varma-Nelson (Indiana U.-Purdue U.). This is the first time that the Norris Award has been given to a group of three people.

Also in the category of Awards, three NESACS members received awards from ACS entities other than NESACS this year. Steve Lantos received the 2008 ACS Division of Chemical Education Northeast Region Award for Excellence in High School Teaching. He received the award at NERM-2008 on July 2nd. Christine Jaworek-Lopes received the 2008 Northeast Regional Award for Excellence in Volunteer Services. She received the award at NERM-2008 on July 2nd. Dorothy Phillips received the Shirley B. Radding Award, given by the Santa Clara Valley local section. “This award was established in 1994 by the Santa Clara Valley Section of ACS to recognize demonstrated, dedicated, unselfish leadership, service and significant contributions, over a sustained period of time, to industrial or applied chemistry and to the American Chemical Society at local, regional and national levels. The award is named for Shirley B. Radding, charter member and long-time supporter of this section.”

NESACS/ACS Scholars This is the eighth year for the involvement of the NESACS in the ACS Scholars Program. The Section renewed its financial commitment to the ACS Scholars program in 2008 by pledging $2500/year over four years. Additionally, the Section invites all ACS Scholars attending academic institutions within the Northeastern Section to attend monthly meetings and dinners as guests of the Section. The NESACS sponsored one student, Jose Barcena, a chemistry major at MIT. In the 2008 calendar year, 21 Scholars were studying within NESACS.

Section Publications Both The Nucleus (the monthly print publication) and the section website (http://www.nesacs.org) are overseen by our Board of Publications. They maintain high standards, and in the past year have made major changes to the website in order to make it more useful for the membership. Dr. Dan Eustace continues his blog (http://blog.nesacs.org/) focusing on career management and development, and has added podcasting to his arsenal of electronic resources for NESACS members.

Education Committee

One of the shining stars of the Northeastern Section is the Education Committee, ably chaired by Prof. Ruth Tanner (UMass Lowell). This committee does a great deal within the Section. Below are some of the highlights of their activities. • The Northeastern Section of the American Chemical Society (NESACS) established the James Flack Norris and Theodore William Richards Undergraduate Summer Scholarships to honor the memories of Professors Norris and Richards by promoting research interactions between undergraduate students and faculty. Four research awards of $3250 were given for the summer of 2008. • The 15th annual Northeast Regional Undergraduate Day sponsored by the Education Committee was held on November 1, 2008 at Simmons in conjunction with National Chemistry Week 19 Activities. The registrants represented colleges and universities from Massachusetts, Rhode Island, Connecticut, New Hampshire, Ohio(Baldwin-Wallace College) and Vermont. The keynote address, “Green Chemistry: Designing a sustainable future with beakers and flasks” was given by Dr. John Warner from the Warner Babcock Institute for Green Chemistry. The program included the seminars, panel discussions, a graduate school/industry fair, and laboratory workshops. • The Education Committee of NESACS co-sponsored the Seventh Annual Undergraduate Environmental Research Symposium held on Saturday, November 15, 2008 at Bridgewater State College. The symposium focuses on undergraduate and graduate research projects, with a special emphasis on environmental issues of particular concern to Southeastern Massachusetts. This Symposium provides an annual forum for discussion of environmental research conducted by undergraduate students in the New England region, and has opened doors to potential research collaborations among the participants. The Symposium featured 54 poster presentations from undergraduate researchers representing colleges and universities from the New England region. Over 100 students, faculty and mentors were in attendance. • Held at the Massachusetts Institute of Technology on April 19, 2008, the tenth annual Research Conference brought together undergraduates, graduates students and postdoctoral fellows from the northeastern region of the country for the purpose of celebrating their accomplishments in research, and for providing a forum for the sharing of ideas and scientific understanding. The keynote address, “Small-Molecule Probe and Drug Discovery” was given by Professor Stuart Schreiber of Harvard University. Thirty-eight poster presentations were given by undergraduate and graduate students and postdoctoral fellows. In addition to the research poster presentations, there were eight student presentations: four each undergraduate and graduate student speakers. The Phyllis Brauner Undergraduate Book Award was presented to Jeffrey Garber (Dartmouth University) for his outstanding presentation. • The 2008 Avery Ashdown Chemistry Exam was held on Saturday, April 5 at Simmons College. Ninety-nine students participated from 26 schools around the section. The Simmons College Prize ($500) was awarded to Simon H. Ye from Andover High School. Our mission with the Ashdown remains three-fold: 1. To use our local section exam as a qualifier for the USNCO exam; 2. To award students for their chemical knowledge and recognize their efforts (and their teachers) on this challenging exam at the annual Education Night awards evening; 3. To increase participation with the exam and continue to publicize our efforts so that more students and schools will take the exam. • Student Affiliate Chapter Awards: Four student affiliate chapters within NESACS were cited. Designated as Commendable was Northeastern University (student leaders: Andrea Lebed, Erin Ronayne; faculty advisor:Thomas Gilbert). Receiving Honorable Mention were Simmons College (student leaders: Amanda Larson-Mekler, Daniella Plourde; faculty advisor: Richard Gurney), Stonehill College (student leaders: Devon Heath, Priscilla Tanger, Cheryl Schnitzer; faculty advisor: Marilena Hall) and Suffolk University (student leaders: Adam Marchetti, Jonathan Urbanczyk; faculty advisor: Doris Lewis). Simmons College was also designated as a Green Student Affiliate Chapter.

Local Section and Chair Goals

2008 Goal Attainment. The Local Section Activities Committee strongly encourages local section planning. As a result, the 2008 local section annual report should follow-up on the attainment of goals. Please list the goals you set at the beginning of your term for your section and yourself, and report on the attainment of the goals.

2008 Section Goals and Assessment:

Goal 1. Create and identify attractive opportunities for active participation in section activities by current/new members 20 Assessment: The YCC in particular has done a good job of reaching out to their constituency and bringing in new members to YCC events. Overall, the section has also managed to come up with some new opportunities for member participation, such as the revamped “Summerthing”.

Goal 2. Effectively and efficiently communicate these

Assessment: Communication within the section is done by (a) publication in The Nucleus; (b) publication on NESACS and YCC websites; and (c) targeted emails to section members who may be interested in a particular activity. This has worked well.

Goal 3. Add new active participants to the section leadership core

Assessment: We were able to bring in a number of new active participants to the section Board of Directors. We continue to pursue this as a goal.

2008 Chair's Goals:

Goal 1: Work with the Program Chair/Chair-Elect to identify and implement different programming types for the section’s monthly meetings, with the goal being to increase average attendance at and interest in the monthly meetings. o Assessment: Attendance is always high at section awards nights, but is still lower than we would like at “regular” meetings. We continue to discuss ways of bringing in more attendance.

Goal 2: Continue to explore possible collaborations with special interest groups such as Silver Circle and WCC with an eye to incorporating branches of these groups within the section. o Assessment: We have made progress in establishing a NESACS WCC. Pam Mabrouk (Northeastern University) is planning a WCC event; it was originally scheduled for September 2008, but had to be rescheduled for early 2009.

Goal 3: Work with the Board of Publications to improve communication within the section (monthly newsletter, website, blog, perhaps targeted emails), in order to inform the membership in as many ways as possible about new section activities o Assessment: The website received a major makeover in 2008, making it easier for the membership to find information. The NESACS blog has continued to flourish, expanding into podcasting as well.

2009 Goals. (This section should be completed by the 2009 local section chair.) Please list below at least three goals that you and your local section plan to accomplish during your term as local section chair.

2009 Section Goals:

1. Our section is a large, well-run operation, but the same few dedicated people fill the elected and non- elected positions year after year. Many of these people have been involved in the section for many years; many are retired. Many committees are "one-man" operations. The section needs to get more NESACS members involved in the operations of the section. Committee chairs will be encouraged to locate and recruit new members for their committees.

2. Our section has a well organized program of monthly meetings. In addition, we have a number of additional programs/events, such as our program of short courses, our annual golf tournament, and the Advances in Chemical Sciences symposium. These attract many people who are not regular attendees at our monthly meetings, or who are not even NESACS members. These events need to be supported and maintained, and additional similar programs developed. 21

3. The Section has the opportunity to collaborate with (and possibly incorporate) some local interest groups such as BAGIM (Boston Area Group for Informatics and Modeling) and BRIC (Boston Regional Inorganic Colloquium).

2009 Chair's Goals:

1. I plan to encourage new people, and especially young people, to join the section leadership. This can be accomplished during my year as chair, and also at the end of my term by nominating new people for elective positions for 2010.

2. I want to try to form some additional "interest groups" within the section, such as a consultants group or retired chemists group, or an interest group focused on analytical chemistry, inorganic chemistry, education, or informatics.

3. There at least three crucial members of the "operating team" of the section: the Treasurer, the Administrative Secretary, and the Nucleus Editor. I hope to work with each of these three to identify and train an assistant, who could take over in cases of vacation, illness, etc.

D. Suggestions/Concerns List any suggestions you have for the Local Section Activities Committee (LSAC). How can LSAC specifically help your section?

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ANNUAL REPORT Northeastern Section, ACS

APPENDIX 1

SUPPORTING DOCUMENTS FOR ACTIVITIES

http://www.nesacs.org

23 APPENDIX 1 - SUPPORTING DOCUMENTS FOR ACTIVITIES

ACTIVITY 1 - CONNECTIONS TO CHEMISTRY

From the Education Committee Report / Appendix 5

On October 16, 2008 NESACS sponsored Connections to Chemistry, a unique program to connect high school chemistry teachers to the educational resources of the ACS and to the members of the Northeastern Section. This is the ninth year for the program. Hosted by Burlington (MA) High School, the program drew over 110 teachers from 76 different high schools in Massachusetts, New Hampshire, Connecticut, Rhode Island, and Maine.

The high school chemistry teachers were welcomed to the program by Ruth Tanner (University of Massachusetts Lowell), Chair of the NESACS Education Committee and Chair of the Connections to Chemistry program; by Steve Lantos, Chair of the High School Education Committee; and by Dr. Thomas Lane, Chair-Elect, ACS. The participants were encouraged to utilize the ACS CHED resources, to consider affiliate membership in the Division of Chemical Education via the new Chemistry Teacher Connection (CTC) program, and of course, to become active in starting a high school chemistry club affiliated with the ACS.

Following the opening, four simultaneous workshops were offered in two sessions to showcase the ACS resources for high school chemistry teachers and students:

Prescribing Success for the Future: Nicole Clark, Intensive Care Clinical Pharmacist, Hallmark Health System The Real CSI Lab: Bill Hebard, Chemist; and Andrea Wilson, Forensic Chemist, Massachusetts State Crime Laboratory “Play Ball”, National Chemistry Week: Patrick Drane, Assistant Director, Baseball Research Center, University of Massachusetts Lowell Let Your Fingers Do the Walking: Liana Lamont, Assistant Editor, Journal of Chemical Education, Department of Chemistry, University of Wisconsin–Madison University

The evening program included dinner and a keynote address And Now for Something Completely Different by Dr. Thomas Lane, Chair-Elect, American Chemical Society, and Director of Global Science and Technology Outreach at Dow Corning Corporation. Following his address, several items were raffled, including American Chemical Society items (mugs and laser pen pointers), subscriptions to the Journal of Chemical Education (2 of which, were donated by the Journal) memberships in CHED (donated by CHED), and memberships in CTC (Chemistry Teacher Connection). In addition, Thomas Lane donated four VISA cards to the raffle each worth $100.00. To conclude the program, participants were given a certificate awarding professional development credits, a year’s subscription to ChemMatters, and a year’s associate membership in the Northeastern Section of the ACS.

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26 ACTIVITY 2 - NORTHEASTERN STUDENT CHEMISTRY RESEARCH CONFERENCE

From the YCC Report / Appendix 5 the Northeastern Section Younger Chemists Committee (NSYCC) and its local Tufts YCC organized the tenth annual Northeast Student Chemist Research Conference on Saturday April 19th at the Chemistry Department of Tufts University. The keynote speaker was Professor Stuart L. Schreiber from the Broad Institute with a lecture titled “Small-molecule Probe and Drug Discovery”. The one day long conference consisted of oral presentations given by the younger chemists from the Northeastern region followed by a poster session where participants discussed their research with their peers and were judged by a NSYCC judging committee. This year’s NSCRC distributed eight awards.

2008 NSCRC awardees Carl Christianson (Boston College) - Strem Excellent Oral Presentation Award Erin Iski (Tufts University) - Vertex Excellent Oral Presentation Award Adam Schell (Boston University) - Vertex Excellent Undergraduate Research Award Margaret Thompson (Wellesley College) - NESACS/YCC Excellent Undergraduate Research Award Raymond Moellering (Harvard University)- Vertex Excellent Graduate Research Award Gülbenk Anarat (Boston University)- NESACS/YCC Excellent Graduate Research Award Jeffrey Garber (Darmouth College) - The Brauner Book Award Wendy Iskenderian (MIT)- GWIS Award

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28 ACTIVITY 3 - NATIONAL CHEMISTRY WEEK ACTIVITIES

29 ACTIVITY 4 - FIFTH ANNUAL NORTHEAST STUDENT CAREER FAIR

From the YCC Report / Appendix 5

In early 2008, however, the economy and hiring environment had changed, and prospects for securing recruiting corporations for the Career Fair seemed pretty bleak. We decided to offer more value to our recruiting sponsors, with pre- and post-event online resume access, free parking at the event, and data CDs of resumes, to name a few. Our recruiters came from past lists, new phone calls, and responses to our announcements in The Nucleus. Recruiters this year included Adante Staffing, the Broad Institute, CreaGen Biosciences, Eisai (ERI), PCI Synthesis, Merck, Nature Publishing Group, and Sigma-Aldrich. As in the past, job seekers could also use the event to learn a bit about the job-seeking process. The ACS Career Services team, led by Dan Eustace, provided valuable and sometimes eye- opening advice regarding resume writing, interview preparation and techniques, as well as turning unexpected (bad) news from interviews into a positive learning experience. While the number of NSCCF job seekers and recruiting corporations was down from 2007, the overall event was still a success. One-on-one conversations between motivated job seekers and corporate recruiters, small group analysis and demonstration of interview skills, and personal attention to resumé content and style ruled the day. The number of younger chemist organizers and volunteers for the event increased from 2007, including UMass Boston, UMass Dartmouth, and Boston University YCC members. We would again like to thank NESACS, the corporate recruiters, the corporate representatives, and job seekers for their participation this year.

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31 ACTIVITY 5 - MEDICINAL CHEMISTRY GROUP MEETINGS & SYMPOSIA

Excerpts from the Medicinal Chemistry Group report / Appendix 5

The medicinal chemistry division of NESACS conducted three excellent symposia during the year 2008. The first symposium was held on May 14, 2008 at Holiday Inn Hotel in Woburn MA. The symposium topic was Cost, Speed, and Quality  Emerging Opportunities for Drug Discovery in Asia. Traditionally medicinal chemistry meetings focus on specific therapeutic areas. However, the main focus of this meeting was to bring the top level executives from prominent contract and collaborative research organizations from Asia to share their expertise and experiences in the drug discovery outsourcing arena. This was all day meeting attended by more than 200 people from local biotech/pharmaceutical companies and many students from academic centers. Chemistry and medicinal chemistry outsourcing, ADME outsourcing and Biology, DMPK, API outsourcing were the three main sessions. Several case studies were part of each session. Panel discussion was also part of the meeting, which was conducted by Dr. Kerry Spear of Sepracor Corporation, Marlborough, MA. The meeting was started by a welcome speech from the co-chair Dr. Liming Shao and keynote presentation was given by Dr. Bradley Miller, Director of Office of International Activities, American Chemical Society Washington DC. Dr. Norton Peet gave the opening remarks. Dr. Raj (SB) Rajur from CreaGen Biosciences, Dr. Steve Tam from Wyeth Pharmaceuticals, Dr. Dingwei Yu from AstraZeneca R&D and Dr. Kerry Spear from Sepracor Corporation chaired the sessions. The meeting was concluded with tasty dinner sponsored by SAPEA New England Chapter. The second symposium was held on September 21, 2008 at the Merkert Chemistry Center of Boston College Chestnut Hill, MA. The meeting was well attended by more than100 participants who enjoyed cutting edge research results presented by four well-known speakers from the pharmaceutical industry. Dr. John Williams, Senior Research Investigator at Microbiotix Corporation, Worcester, MA spoke on Nucleosides and the Challenge of Antivirals: ZSM-I-62 as a Candidate Anti-HCMV drug. Dr. Gregory S. Bisacchi, Associate Director at AstraZeneca R&D Boston spoke on Antibacterial Discovery: Past, Present, and Future. Dr. Roger Frechette, VP of Chemistry and R&D Operations at MaxThera, Inc, Beverly, MA spoke on the development of new antibiotics. The social hour, networking and dinner were part of the program. The keynote speaker for the evening was Dr. Milind Deshpande, Executive Vice President and Chief Scientific officer at Achillion Pharmaceuticals, New Haven, CT. Dr Deshpande spoke on the Discovery of Potent Antibacterial Agents for Treatment of Highly Drug-Resistant Pathogens. The symposium was well attended and there were more than 80 participants

The third and the annual symposium for the year 2008, was held on December 10, 2008 at Holiday Inn Hotel in Woburn MA. This symposium was a great success. There were more than 100 participants who enjoyed the topic New Technologies for Drug Discovery. Dr. John A. Porco, Jr. , Professor and Director of Boston University Chemical Methodology and Library Development Center at the Boston University, Boston, MA spoke on New Approaches for Discovery of Chemical Reactions and Chemotypes. Dr. Scott L. Harbeson, Vice President of Research at Concert Pharmaceuticals, Inc. Lexington, MA spoke on Selective Deuterium Chemistry in Drug Discovery: Improved New Chemical Entities from Clinically Validated Therapeutics. The keynote speaker for the evening was Dr. Christopher G. Newton, Senior Vice President, at BioFocus DPI, Chesterford Research Park, Saffron Walden, Essex, UK. Dr Newton Spoke on Drug Discovery in the 21st Century - the Collaborative Paradigm”.

32 Sample announcement from the Nucleus:

33

34

ACTIVITY 6 - FOURTH ANNUAL NESACS GOLF TOURNAMENT

From Fund-raising Committee Report / Appendix 5

Fourth Annual Golf-Tournament was held June 25, 2008. Funds came from the contributions made by companies as sponsors of holes. Each golfer paid a fee to play. Announcement published in May 2008 edition of Nucleus shown below. Primary organizers: Amy Tapper and Harry Mandeville

From the Nucleus

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36

ACTIVITY 7 - SUMMERTHING 2008

From Summerthing report, Appendix 5

This year’s Summerthing was a very successful commemoration of Wally Gleekman’s long association with Summerthing activities at Fenway Park. A sold-out purchase of 60 seats, many of them bought by the high school teachers from Wally’s contact list, enjoyed a day at Fenway Park with their families (see Nucleus article below). An enthusiastic Summerthing group plans expanded activities next year, with more tickets purchased and ( we hope) Summerthing hats with the NESCAS emblem honoring Wally Gleekman as well.

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ACTIVITY 8 - 2008 GERMAN-NSYCC EXCHANGE

From YCC report / Appendix 5

2008 German-NSYCC Exchange

The German Chemical Society (Gesellschaft Deutscher Chemiker, GDCh), and its Young Chemists Forum (Jung-Chemikerforum, JCF), welcomed to Germany 12 representatives of the NESACS Younger Chemists Committee (YCC) who had been selected by the German Exchange program steering committee. The delegates were accompanied by Prof. Ruth Tanner (University of Massachusetts Lowell), Prof. Mort Hoffman (Boston University- Professor Emeritus) Mike Strem (Strem Chemicals) and Dr. Bob Lichter (Merrimack Consultants, LLC). The visit came as the eight annual exchange program between the NESACS-YCC and GDCh-JCF, highlighting the close connection between the NESACS and the GDCh.

The weeklong program began on Wednesday, March 26th, with a day in Rostock and a tour of Rostock University. On Thursday Wendy Iskenderian (MIT) spoke in Frühjahrssymposium about her research. At the end of the day, a poster session was held where the American graduate and undergraduate students displayed their research posters and discussed their scientific progress. In addition, on Friday two students, Brett Fors (MIT) and Raymond Moellering (Harvard University), contributed oral presentations while the rest of the American group discussed their posters. At the end of the day, Frühjahrssymposium hosted a dinner coupled with a social evening where the American contingent had the opportunity to network with their German peers. On Saturday morning, Patrick Cappillino (Boston University) gave an oral presentation and received the third place award for best oral presentation. In addition, Shuyu Wang (Harvard University) was awarded a prize for best poster presentation.

In addition to the scientific talks, the program included a four-day stay in Hamburg, where students had the chance to visit Hamburg University and local laboratories such as Dow Chemical. At the end of the week, Dr. Kurt Begitt, Deputy Executive Director and Director of Education and Professional Affairs of the GDCh accompanied by representatives of the Young Chemists Forum (Jung-Chemikerforum,JCF) hosted a farewell dinner in honor of the American delegation. Looking ahead to the 2009 exchange program, the application will be available at the end of the summer. A delegation from NESACS will travel to Essen, March 11- 18 for the Frühjahrssymposium. We hope that NESACS-YCC and GDCh-JCF exchange continues and we look forward to greeting JCF to Boston in August 2010.

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ACTIVITY 9 - NESACS CELEBRATES EARTH DAY

From The Nucleus and Annual Report, Appendix 5

39

ACTIVITY 10 - ADVANCES IN CHEMICAL SCIENCES SYMPOSIUM

From the Professional Relations report - Appendix 5

The “Advances in Chemical Sciences Symposium”, was held on April 11, 2008: it was a spectacular success. The symposium, a day-long celebration of Chemistry was held at the Royal Sonesta Hotel in Cambridge, MA. Under the auspices of this conference, eminent scientists delivered plenary lectures. The conference brought together 300+ scientists for a scholarly event focusing on medicinal chemistry, organic synthesis and methodology. The plenary lecturers were Magid Abou-Gharbia, (Wyeth), Mark Goulet, (Merck Research Laboratory), Timothy F. Jamison, (Massachusetts Institute of Technology) John Piwinski, and (Schering Plough). Mathew Shair, (Harvard University), Eric J. Sorensen, (Princeton University). The topical focus areas – medicinal chemistry, pharmaceutical and organic synthesis are areas where the chemical enterprise in our area has a well deserved reputation for excellence.

A large number of pharmaceutical and biotechnology industry professionals from the metropolitan area joined us for this event, shared ideas and built networks. The response has been extremely enthusiastic. A sell out symposium crowd was treated to some exhilarating science from some of the finest practitioners of the discipline. A vendor show has already drawn 16 vendors. The symposium is co- sponsored by the US (East Coast) Section of the RSC, and IUPAC. This helps cement our relationships with our colleagues from other societies. Represented on the organizing committee were scientists from many of the Pharma companies in our area. We thus continue to build a nucleus for the future: there is a lot of enthusiasm for having this as an annual event. Our new Chair-elect is a distinguished member of the pharmaceutical community in our section.

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ANNUAL REPORT Northeastern Section, ACS

APPENDIX 2

BUDGETS AND LONG-RANGE PLAN

Budgets and Long-Range Plan provided below -- uploaded into ACS S.O.L.A.R. report.

http://www.nesacs.org

41 Northeastern Section 02/14/2008 Budget Proposal 2007 2007 2008 2008 2008 Annual Account # Budget Actual Requests Proposed Proposed From REVENUE General Offsetting Acct National Allotment 10 31,813.00 31,813.00 32,819.00 Travel Grants 11 11,250.00 14,656.25 18,000.00 Local Dues 12 55,000.00 57,073.99 62,000.00 New-member Commission 13 50.00 60.00 50.00 Contributions 14 32,000.00 32,835.00 14,500.00 Other Program Income 15 30,760.00 28,548.20 36,060.00 Project SEED 16 0.00 0.00 Continuing Education 17 1,000.00 0.00 1,000.00 Dinner Receipts 18 7,000.00 6,220.00 5,000.00 Savings Interest 19 200.00 131.29 200.00 Miscellaneous 20 0.00 7,401.80 100.00 Trustees: Cons. Acct. 21 750.00 0.00 750.00 Perm. Inc. Acct. 22 7,675.00 12,809.65 9,375.00 Norris Inc. Acct. 23 23,250.00 45,312.22 31,100.00 Richards Inc. Acct. 24 8,650.00 9,528.65 13,800.00 Publ. Inc. Acct. 25 8,000.00 9,000.00 8,000.00 Hill Award 26 1,500.00 2,441.89 1,500.00 Esselen Award 27 14,000.00 17,940.58 14,000.00 Levins Award 28 700.00 640.00 700.00 Brauner Lecture 29 2,000.00 2,000.00 2,000.00 NERM/Nat'l Meeting 30 4,500.00 7,056.92 Summer Programs 31 500.00 418.50 500.00 Advertising 32 48,000.00 30,636.50 42,000.00 REVENUE TOTALS 288,598.00 316,524.44 109,569.00 183,885.00 TOTAL REV 293,454.00 EXPENSE Chair 50 2,000.00 2,161.20 2,000.00 2,000.00 Business Office 51 800.00 1,113.66 1,100.00 Treasurer 52 4,600.00 4,587.59 4,850.00 850.00 4,000.00 22 Archivist 53 200.00 0.00 400.00 Website 54 4,000.00 5,099.56 11,000.00 4,000.00 2,000.00 25 Nucleus 55 70,457.00 67,651.74 65,267.00 16,267.00 48,000.00 see notes Program 56 22,000.00 21,167.91 1,000.00 Ballots 57 2,000.00 1,954.95 2,000.00 Fundraising 58 10,200.00 10,573.07 golf + 500 7,500.00 15 Career Services 59 1,500.00 465.10 2,500.00 1,500.00 100.00 20 Education 60 12,175.00 7,662.02 12,325.00 8,650.00 2,960.00 15 Newell Grants 61 1,000.00 225.00 1,000.00 1,000.00 22 Ashdown Awards 62 2,000.00 1,666.33 2,500.00 1,400.00 600.00 15 Continuing Education 63 1,000.00 0.00 1,000.00 17 Local Arrangements 64 18,000.00 21,779.22 13,000.00 5,000.00 18 Membership Committee 65 600.00 695.06 800.00 700.00 Hill Award 66 1,500.00 1,408.27 1,500.00 26 Norris Award 67 16,000.00 18,022.96 16,000.00 23 Speakers Bureau 68 400.00 0.00 400.00 23 Norris/Richards Undergrad Res 69 13,700.00 11,159.23 14,700.00 14,700.00 23 Project SEED 70 5,000.00 3,001.95 9,000.00 7,750.00 Richards Medal 71 0.00 35.00 12,000.00 24 Esselen Award 72 14,000.00 16,821.84 14,000.00 27 Levins Prize 73 700.00 610.28 700.00 28 Sec. School Award 74 1,800.00 1,745.92 1,800.00 24 Aula Laudis 75 375.00 464.98 375.00 375.00 22 Trustees 76 750.00 601.46 750.00 21 Chair-elect 77 1,700.00 516.20 1,700.00 1,000.00 National Chem. Week 78 9,650.00 12,343.88 11,725.00 9,000.00 2,000.00 29 Summer Programs 79 500.00 334.64 500.00 31 ACS Scholars 80 2,500.00 2,500.00 5,000.00 4,000.00 22 Medicinal Group 81 6,500.00 3,781.19 7,750.00 6,500.00 Travel Grants 82 15,000.00 20,266.02 8,500.00 18,000.00 11 Adm. Secretary 83 18,500.00 18,919.00 18,500.00 Miscellaneous 84 500.00 509.58 500.00 42 NERM/Nat'l Meeting 85 6,000.00 4,146.19 1,000.00 1,000.00 Younger Chemists Comm 86 10,920.00 12,694.98 5,000.00 5,000.00 15 Jung Chemiker 87 26,000.00 25,780.87 12,000.00 12,000.00 14 Women's Chemist Committee 88 3,000.00 1,500.00 Adv in Chem Science Symposium89 20,000.00 15 EXPENSE TOTALS 304,527.00 302,466.85 124,117.00 183,885.00 TOTAL EXP 308,002.00 Notes to the 2008 Budget Proposal 02/14/08 Expense accounts for which budget requests were received are shown. The "From Account" column shows the income accounts which fund the "Offset" expense budget amounts. In the places where there are two numbers, the breakdown is shown below. The budget is in deficit by $11,798 with cash on hand of about $37,000 on 12/31/07.

12 Local dues have increased from $16 to $20 but we will only see half of the increase this year. 14 Contributions are projected from Golf ($7500 ), Fundraising ($2000) and the Advances in Chem Sciences Symposium (ACSS) ($5000). 15 Other Program Income. Consists of the offsetting income from Golf, ACSS Symposium, Education and YCC activities as noted in expense categories offset by account 15. 21-29 Trustees. Approval of the budget constitutes the approval to transfer the budgeted amounts from the Trust Funds for expenditures as indicated in the expense items. In addition, the National Norris Award will cost about $9,000. 52 Treasurer. $4000 is for the CPA audits required by Massachusetts and $850 for Treasurer's expenses. 54 The request was for $10,000 for general expenses for the website and $1000 for a directory. The Budget Committee reduced the line to $6000 including $2000 from the Publication Trust. 55 Nucleus Budget Request. EXPENSE: Three 16 page issues 14424.00 Four 20 page issues 21320.00 One 24 page issue 5852.00 Two 28 page issues 12928.00 Adding links to website in pdf files 1000.00 Ballots (4 pages) 2243.00 Ad Manager 10500.00 Business Manager, Piper Ent. 2100.00 Office & Committee expense 1400.00 Reduced by Budget Committee -2000.00 69767.00 INCOME: Advertising 42000.00 Publications Trust 6000.00 Norris Award Fund (In line 67 budget) 5500.00 General Funds (55) 16267.00 69767.00 58 Fundraising expense by the Fundraising committee ($500) and golf expenses. 60 Education. The Budget request was for $12,325 including $500 for May meeting expenses, $1500 for Undergraduate Day offset by $800 income, $1725 for the Student Research Conf., $1000 for Student Affiliates, $1400 for travel grants for undergraduates, $5200 for Connections to Chemistry offset by $2160 of registration fees, $1000 for ACS Scholars. The Budget Comm. reduced the total by $715. 17,63 Continuing Education. The $1000 in these lines may be any offsetting amounts. 64 Dinner and AV costs 66 Hill Award. The budget funds dinners for guests at the local award plus $1000 for the NOBCChE Hill lectureship. 69 Norris Richards Research Scholars. This budget request includes 4 scholarships at $3000 plus $500 for each of the four institutions, $350 for a travel grant, and $700 for expenses. The Norris Trust funds all of this year's awards. 70 Project SEED. The ACS matches student stipends, but the amount here is only the Section's share. The Budget Committee reduced the line to $5000. 72 Includes $600 for contracted secretarial services to Piper Enterprises. 76 Trustees. Includes $500 for secretarial services by Piper Enterprises. 77 Chair-elect. Travel and registration to leadership meetings. 78 National Chem Week. $2000 is budgeted from the Brauner Trust for an honorarium. The Budget Comm reduced the line

43 79 Summer Programs. As for continuing education, income should offset expenses. 80 ACS Scholars program. Our student will be a junior for whom the scholarship is $5000. The Budget Comm. reduced 82 Travel Grants. National pays slightly less than 75% of costs up to a specified maximum. 83 Adm. Secretary 86 Younger Chemists. There was no budget request. Last year included $3500 for the April Research Conf., $6000 for a career fair offset by $5000 of income, $300 for a Career Symposium, and $1120 for other events. The Budget Comm. reduced the total to $10,000. 88 Women Chemist's Committee - a new budget submitted by Pam Mabrouk. The Budget Comm. reduced this to $1500. 89 ACSS - year 2 of the symposium. Income is expected to exceed expenses (see line 14).

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46 COMBINED BOARD MEETING AND LONG-RANGE PLANNING MEETING

WEDNESDAY, JULY 16, 2008 1:00 P.M. SCIENCE CENTER CONFERENCE ROOM (See specific directions to room below) UNIVERSITY OF MASSACHUSETTS BOSTON

Board Meeting

New Business: There will be an abbreviated meeting of the Board of Directors for the purpose of filling vacancies on the Board. Votes will be needed to fill vacancies in the positions of Alternate Councilor and Director-at-Large.

Long-Range Planning Meeting Items

Science Club for Girls – invitation from Connie Chow, the Executive Director, for NESACS members to participate

“Technology Milestones” presentation sent to me by Attila Pavlath, past-chair of ACS

Review of Cvent information relating to contracted services to manage Section activities. Information obtained from an on-line demonstration and follow-up phone call.

Electronic elections - “I am pleased to report that the complete text and audio transcripts of the May 28 teleconference on Best Practices for Electronic Elections in Local Sections and Divisions have been posted to the www.acs.org website.”

IF YOU HAVE ADDITIONAL ITEMS FOR THE LONG-RANGE PLANNING MEETING, PLEASE FORWARD THEM TO MARIETTA SCHWARTZ AS SOON AS POSSIBLE. [email protected]

Information received from Marietta Schwartz:

Here’s a link for directions, which also has parking info. http://www.umb.edu/parking_transport/directions.html. I would expect that most people would park in the North Lot or take the T. Either way, you wind up in the campus center.

To get to the science building, go up the stairs (or elevator) to the first floor/plaza level and walk out of the building. The building right in front of you is the science center. Walk along the side of it (it will be on your right) until you get to the door. Go into the lobby, turn left before the stairs, go through the orange fire door (you will walk right by the main chemistry office). The conference room is the last door on the left

47 Board of Directors Northeastern Section, American Chemical Society Long-Range Planning Meeting July 16, 2008, UMass Boston, 1:00 PM

Members attending: Don Rickter, Michaeline Chen, Joe Billo, Christine Jaworek-Lopes, Raj Rajur, Cathy Costello, Bob Lichter, Don Smith, Jim Piper, John Neumeyer, Kathi Browne, Mort Hoffmann, Mary Burgess, Marietta Schwartz

1. Formal Board actions required for the following:

a. Filling the open Alternate Councilor position (2007-2010) created by the resignation of Eriks Rozners, who left the section. According to NESACS tradition, this vacancy is normally offered to the top vote receiver amongst the runners up in the election year with the vacancy. That person is Mukund Chorghade. He has been contacted and has agreed to serve. The Board unanimously approved the appointment.

b. Filling the open Director-at-Large position. Last year Steve Lantos was the only candidate for two spots, and Myke Simon was appointed to fill the other spot. Myke's term from that appointment expires on 12/31/08 and he was just elected to a new term as Director beginning January 1, 2009. That will still leave five Directors on the Board for next year instead of six. According to NESACS tradition, the top vote receiver amongst the runners up in the election year with the vacancy is offered the open position. Since there is no such person, we turn to the top vote receiver amongst the runners up in the next election year from the vacancy. That person is Mukund Chorghade. The two newly elected Directors are Myke Simon and Ralph Scannell. The Board unanimously approved the appointment of Mukund to fill the vacancy, but felt that the terms should be shifted around. In other words, Ralph Scannell should be invited to take the currently vacant spot (the 2008-2010 term) and Mukund should be appointed to the later spot (2009-2011). Mukund has indicated his willingness to serve as Director-at-Large.

2. Announcements: various awards.

a. Steve Lantos received the 2008 ACS Division of Chemical Education Northeast Region Award for Excellence in High School Teaching. He received the award at NERM-2008 on July 2nd.

b. Christine Jaworek-Lopes received the 2008 Northeast Regional Award for Excellence in Volunteer Services. She received the award at NERM-2008 on July 2nd.

c. Dorothy Phillips received the Shirley B. Radding Award, given by the Santa Clara Valley local section. “This award was established in 1994 by the Santa Clara Valley Section of ACS to recognize demonstrated, dedicated, unselfish leadership, service and significant contributions, over a sustained period of time, to industrial or applied chemistry and to the American Chemical Society at local, regional and national levels. The award is named for Shirley B. Radding, charter member and long-time supporter of this section.”

48 d. NESACS has been nominated for five ChemLuminary Awards. Mukund Chorghade will represent the section at the award banquet at the Philadelphia meeting in August.

3. Various other incoming.

a. An email was received from the president of the Students’ Chemical Society of the Kwame Nkrumah University of Science and Technology, Kumasi-Ghana, West Africa. They wish to “establish a relationship between SCS-KNUST and [our] society where we could share chemical and fraternal ideas”. This may be an opportunity for one of the more active Student Affiliate chapters. Marietta will forward the email to Don Rickter (whose son is in Ghana) and to Bob Lichter.

b. Mike Strem forwarded an article from the Newburyport News on a high school visit by three chemists from Strem Chemicals that was very well received.

Link: http://www.newburyportnews.com/archivesearch/local_story_136204400.html. He encouraged all NESACS members to look into similar activities in their local communities. We will ask that the article be linked to the NESACS web page, highlighting exemplary community service by section members.

c. The complete text and audio transcripts of the May 28 teleconference on “Best Practices for Electronic Elections in Local Sections and Divisions” has been posted on www.acs.org. Cathy Costello attended the teleconference, and reported back to the group. She says that this is the coming thing – there are some local sections and divisions that have been running electronic elections on a trial basis with good results. NESACS would have to change the bylaws before we could actually do electronic elections. Such a request has to be initiated by the Committee on Nominations and Elections. There was some discussion on the best way to make the switch; after a few minutes it was obvious that what was really needed was a task force. Joe Billo will head up the task force; Bob Lichter, Mort Hoffmann, and John Neumeyer will join him. They will report back to the Board early this fall.

d. A request for “sponsorship” was received from the Science Club for Girls. This is a Cambridge-based organization that is moving into other area towns. They match girls in grades 8-12 with women scientist mentors and do many other meritorious activities. The Board thought that this might be a good project for our nascent WCC to take on. Christine also said that she would add them to her email list for NCW and Earth Day activities. Marietta will forward the emails appropriately.

e. This begged the question – “What is Sponsorship?” It could mean money, it could mean lending our good name, inviting submissions to The Nucleus, posting notices on our web page… all sorts of possibilities. Mort informed the Board that National ACS has a mechanism for dealing with these sorts of requests (a simple form and procedure). He agreed to look at that mechanism and propose a modification for NESACS consideration.

49 We are getting more and more of these sorts of requests, and it would be a good idea to have a standardized method for handling them.

f. CVent – an online event management group – had an online teleconference last month. Marilou Cashman attended on behalf of NESACS and provided a large stack of information. The Board’s feeling was that this sort of online event planning is probably too expensive for the section. It was also noted that it was rather impersonal – one of the nice things about the meeting registration is getting to actually meet people and chat with them. However, it was pointed out that it would be very useful for the section to be able to accept credit cards as payment for meeting attendance (especially the big MedChem meetings, where many attendees might be able to use corporate credit cards). We will ask Marilou to investigate.

g. Attila Pavlath, Past President of ACS, sent the section a copy of an electronic exhibit that he had put together on “Technology Milestones from the Chemist’s View”. The Board felt that sections of it might be useful as part of an NCW event; accordingly, the CD was given to Christine Jaworek-Lopes for her files.

h. Michael Singer pointed out via email that three of the USA Chemistry Olympiad Team members will be attending college within NESACS (one at Harvard, two at MIT). He thought that this was a great opportunity to get younger people involved in the section. The Board heartily agreed. We will attempt to get contact information from National ACS; then the Chair will call them with congratulations, welcome them to the section, and invite them to attend the October meeting. Christine will see about getting them involved in the high school program part of NCW; Mort will look into inviting them to the Connections to Chemistry program in October.

i. Bob Lichter led a discussion on more efficient ways of engaging the ACS Scholars in the section. There are 20-30 ACS Scholars in the area at any given time; we haven’t been terribly successful in getting them to participate in any sort of event. Bob also noted that he isn’t going to be in Boston as much, and is going to have to hand over leadership in this area to someone else. Mort noted that we have an ACS Scholar alumna in the area (Shanadeen Begay, a graduate student at BU), who is becoming more active in the section. Perhaps she might take a leadership role. Bob is willing to continue in an advisory role. He will talk to Shanadeen.

4. Programming. There was an extensive discussion on ways to get more people to attend our meetings. Spread the meetings around geographically; try to get people outside of greater Boston involved in meeting arrangements. Bob noted that so many of our monthly meetings are already scripted; it is difficult to allow for much creativity in programming. Joe wants to get more “interest groups” (such as MedChem) involved and doing separate programming. Don noted that multi-speaker meetings are popular, but they cost more. Mort thinks that we should tap into local seminar programs – if someone interesting is coming from out of state, perhaps we could share expenses and have them speak to our membership as well. Bob said that we should also target younger chemists – new hires, assistant professors. John thinks that the budget committee should 50 prioritize – if programming is a priority for the section, then we should put more money there. Bob suggested a retreat to focus on programming. Joe will discuss this all with John McKew (next year’s Program Chair) so that he can take it to the next level. This is long-range planning, after all!

5. NERM. Mort is the NESACS representative to the NERM board. They are still looking at NERM-2011. There had been some thought that it might be a joint NERM/MARM, but that would require participation by a MARM section, and Northern New Jersey, the obvious choice, declined to participate. Now it appears that the Central Massachusetts section is interested in hosting the meeting, but they are hoping that NESACS is willing to help out. The Board decided that we wouldn’t say no at this stage; we’d wait and see what comes of it, and we’d be willing to help out if it seems like the meeting is viable.

Meeting adjourned at 3:15 PM.

Respectfully submitted, Marietta Schwartz Chair

51

ANNUAL REPORT Northeastern Section, ACS

APPENDIX 3

MEMBERSHIP SURVEYS AND NEWSLETTER

http://www.nesacs.org

A. Membership Survey Conducted in 2008

No membership survey was conducted in 2008

B. 2008 Newsletter

The May 2008 issue of The Nucleus was uploaded into the ACS SOLAR report. http://www.nesacs.org/TheNucleus/May08-wLINKS_2D.pdf

52

ANNUAL REPORT Northeastern Section, ACS

APPENDIX 4

PUBLIC RELATIONS PLAN TALKS TO PUBLIC NEWSPAPER CLIPPINGS

No Public Relations Plan was prepared in 2008 Talks to Public included here and uploaded into the SOLAR report Newspaper Clippings are not available for this report

http://www.nesacs.org

53 TALKS TO THE PUBLIC By NESACS Members

Note: The following list contains information that was published in The Nucleus in 2008. Other NESACS members were speakers at various events that were not published in The Nucleus.

Grant-in-Aid: ACS National Meeting - New Orleans - April 2008 NSCRC - Boston - April 19, 2008 Kevin Robbins, Keene State College New Soft Scorpionate Complexes of Vanadium Jeffrey Garber, Dartmouth College Amphiphilic Block Copolymer Precursors to Colbalt Polymer Hybrids Jonathan Doran, University of Masschusetts Dartmouth Nucleophilic Displacement Reactions January 10 Monthly Meeting - Holiday Inn, Brookline, MA Dr. Hannah Sevian, University of Massachusetts Boston Incremental Movement Toward an Inquiry Lab Curriculum In General Chemistry: Can Changing a Single Laboratory Experiment Improve Student Performance? February 4 Harvard University Dr. Paul Clemons, Broad Institute of Harvard and MIT Merck Lecture February 4 Harvard University Dr. Mark Goulet, Merck Merck Lecture February 5 University of New Hampshire Dr. Alan Packard, Children’s Hospital / Harvard Medical School TBA February 11 Boston University Dr. Mohammad Movassaghi, MIT Cascade Reactions in Complex Alkaloid Synthesis February 13 University of Massachusetts Dartmouth Dr. Yi Sun, Dartmouth, MA February 14 Monthly Meeting - Simmons College, Boston, MA Dr. Joyce P. Foster, Williams College Dr. Valerie P Wilson, Brown University Mentoring Matters across the Diverse Populations in the Academy February 20 University of Massachusetts Dartmouth Dr. Barry Snider, Brandeis University TBA February 27 Northeastern University Dr. Sunny Zhou, Northeastern University TBA March 13 Monthly Meeting - Harvard Faculty Club Dr. Gary Weisman, University of New Hampshire Theodore William Richards March 4 University of New Hampshire Dr. John L. Marshall, Zink Imaging, Inc. 54 Zero Ink - Aorphochromic Dyes and Thermal Printing March 20 Harvard University Dr. Mohammad Movassaghi, MIT Boehringer-Ingelheim Symposium March 17 Brandeis University Dr. John R. Engen, Northeastern University TBA April 14 Boston University Prof. David Evans, Harvard University YCC Colloquium April 15 University of New Hampshire Dr. Yvon Durant, University of New Hampshire Synthesis of Multifunctional Nanoparticles for Biomedical Applications April 17 Monthly Meeting - Harvard Faculty Club Joseph A. Lima, Houghton Chemical Company, Boston Welcome - Esselen Award Dinner Dr. Myron S. Simon, NESACS The Esselen Award April 28 Brandeis University Dr. Steve Bruner, Boston College TBA May 1 University of New Hampshire Dr. Donald Sundberg, University of New Hampshire Synthetic Control & Analytical Evidence of the Physical Structure of Composite Polymer Nanoparticles May 8 Monthly Meeting - Northeastern University Dr. Angela Belcher, MIT From Nature and Back Again . . . Giving new life to Materials for energy, electronics and the environment May 13 Cost, Speed & Quality: Emerging Opportunities for Drug Discovery in Asia Holiday Inn, Woburn, MA Dr. Liming Shao, Sepracor, Marlborough, MA Opening Remarks, Medicinal Chemistry Symposium Dr. Raj (SB) Rajur, CreaGen, Woburn, MA Moderator, Medicinal Chemistry Symposium Dr. Steve Tam, Wyeth, Boston, MA Moderator, Medicinal Chemistry Symposium Dr. Kerry Spear Moderator, Medicinal Chemistry Symposium The Role of China in Drug Discovery through Integrated Chemical Operations May 20 Hampton Inn, Natick, MA New England Section: Society for Applied Spectroscopy Dr. Xiaowei Zhuang, Harvard University Single-Molecule and Super-Resolution Imaging of Biomolecules and Cells Sept 11 Monthly Meeting - Boston College Joint meeting with Medicinal Chemistry Group 55 Dr. Raj (SB) Rajur, CreaGen BioSciences, Woburn, MA Introductory Remarks Dr. Norton Peet, International Consultant, No. Andover, MA Introductory Remarks Dr. John Williams, Microbiotix, Worcester, MA Nucleosidesand the Challenge of Antivirals: ZSM-I-62 asa Candidate Anti-HCMV Drug Dr. Gregory S. Bisacchi, AstraZeneca R&D Boston Antibacterial Discovery: Past, Present and Future Sept 24 University of Massachusetts Dartmouth Dr. Bela Torok, University of Massachusetts Boston Organofluorine Chemistry: Synthetic and Medicinal Applications Oct 2 Harvard University Dr. Troy van Voorhis, MIT TBA Oct 6 Harvard University Dr. Stephen L. Buchwald, MIT TBA Oct 8 Northeastern University Dr. Ira Krull, Northeastern University Characterization of Recombinant Human Monoclonal Tissue Necrosis Factor-alpha Antibody Using Capillary Isoelectric Focusing, Cation Exchange, Size Exlusion, Chromatography And Mass Spectrometry Oct 8 University of Massachusetts Dartmouth Dr. Christopher Doona, US Army NSRDEC Comparing the Quasi-chemical and other models for controlling Food borne microbes using novel technologies Oct 15 University of Massachusetts Dartmouth Dr. Melisenda McDonald, University of Massachusetts Lowell TBA Oct 15 Monthly Meeting - Northeastern University / Henderson House Dr. Michael Singer, Sigma-Aldrich Acceptance of Henry Hill Award Dr. Peter Meltzer, Organix, Inc., Woburn, MA The Establishment & Evolution of a Small Chemical Business In Massachusetts Oct 18 NCW / Museum of Science Boston Dr. Bassam Shakhashiri (honorary NESACS member) Having a Ball with Chemistry Oct 21 University of New Hampshire Dr. Barry Snider, Brandeis University TBA Oct 22 University of Massachusetts Cartmouth Dr. Charles E. Kolb, Aerodyne Research, Inc., MA TBA Nov 1 Simmons College, Boston, MA 15th Annual ACS Northeast Regional Undergraduate Day Speakers: Dr. Rich Gurney, Simmons College 56 Welcoming Remarks Dr. John C. Warner, Warner Babcock Institute for Green Chemistry Keynote Speaker: Green Chemistry: Designing a Sustainable Future with Beakers and Flasks Dr. Nolan T. Flynn, Wellesley College An REU-based research group and metal nano- Particles: Controlling assembly at different length Scales Amy Cannon, Lowell, MA Beyond Benign Nov 4 Boston College Dr. John Porco, Boston University Organic Chemistry Seminar Nov 5 Northeastern University Dr. John Porco, Boston University New Synthetic Methods Inspired by Complex Natural Products Nov 6 Harvard University Dr. Moungi Bawendi, MIT TBA Nov 11 Boston College Dr. Catherine Drennan, MIT TBA Nov 13 Brandeis University Faculty Club Norris Award Dinner Dr. Mary Mahaney, NESACS Presentation of the Arno Heyn Book Prize Dr. Myron S. Simon, NESACS Speaking on James Flack Norris Dr. Morton Z. Hoffman Introductory Remarks on the Norris Award Dr. Barry Snider, Brandeis University Presentation of the Norris Award Nov 19 Northeastern University Dr. Anne Gershenson, Brandeis University Watching Protein-Lipid Ineractions Using Single Molecule Fluorescence Dec 5 University of Massachusetts Lowell Sukant Tripathy Annual Memorial Symposium Speakers: Peggy Cebe, Tufts University Thomas Jozefiak, Genzyme Corporation Dec 10 Monthly Meeting Joint Meeting with Medicinal Chemistry Group Symposium: New Technologies for Drug Discovery Speakers: Dr. Raj (SB) Rajur, CreaGen BioSciences, Woburn, MA Introductory Remarks Dr. Norton Peet, International R&D Consultant Introductory Remarks Dr. John A. Porco, Jr., Boston University New Approaches for Discovery of Chemical 57 Reactions and Chemotypes Dr. Scott L. Harbeson, Concert Pharmaceuticals, Lexington Selective Deuterium Chemistry in Drug Discovery: Improved New Chemical Entities from Clinically Validated Therapeutics

58

ANNUAL REPORT Northeastern Section, ACS

APPENDIX 5

AS NEEDED BY SECTION NESACS REPORTS

http://www.nesacs.org

59

NORTHEASTERN SECTION OFFICERS / COUNCILORS / CHAIRS -- 2008

Chair Dr. Marietta Schwartz Chemistry Department, University of Mass. Boston, Boston, MA 02125-3393 (P) 617-287-6146 [email protected]

Chair-elect Dr. E. Joseph Billo 13 Shattuck Street, Natick, MA 01760 (P) 508-653-3074 [email protected]

Past-Chair Dr. Mukund S. Chorghade 14 Carlson Circle, Natick, MA 01760 (P) 508-651-7809 (F) 508-651-7920 [email protected]

Secretary Dr. Michael Singer Sigma-RBI, 1 Strathmore Road, Natick, MA 01760 (P) 508-651-8151 x291 (F) 508-655-1359 [email protected]

Treasurer Dr. James U. Piper 19 Mill Road, Harvard, MA 01451 (P) 978-456-8622 (F) 978-456-8949 [email protected]

Auditor Dr. Anthony L. Rosner 1443 Beacon Street, Apt. No. 201, Brookline, MA 02446 (P) 703-276-7455 (F) 703-276-8178 [email protected]

Trustee Dr. Esther A. H. Hopkins 1550 Worcester Road, Unit 309, Framingham, MA 01702 (P) 508-872-8148 [email protected]

Trustee Mr. Joseph A. Lima 11 Morningside Avenue, Natick, MA 01760 (P) 617-244-5764 (F) 617-254-2713 [email protected]

Trustee Dr. Michael E. Strem Strem Chemicals, Inc., 7 Mulliken Way, Newburyport, MA 01950 (P) 978-499-1600 [email protected]

Councilor Miss Mary Burgess 63 Weld Hill Street, Boston, MA 02130-4150 (P) 617-522-9165 [email protected]

60 Councilor Mrs. Michaeline Chen 529 Grove Street, Needham, MA 02492 (P) 781-235-5201 [email protected]

Councilor Dr. Catherine Costello B. U. School of Medicine, 715 Albany Street R-806, Boston, MA 02118-2394 (P) 617-638-6490 (F) 617-638-6491 [email protected]

Councilor Dr. Thomas Gilbert Chemistry Department, Northeastern University, Boston, MA 02115 (P) 617-373-4505 (F) 617-373-8795 [email protected]

Councilor Dr. Robert Lichter Merrimack Consultants, Inc., Box 963, Great Barrington, MA 01230 (P) 413-528-9681 [email protected]

Councilor Dr. Morton Z. Hoffman Chemistry Department, Boston University, Boston, MA 02215-2507 (P) 617-353-2494 (F) 617-353-6466 [email protected]

Councilor Dr. Christine Jaworek-Lopes Emmanuel College, 400 The Fenway, Boston, MA 02115 (P) 617-264-7614 [email protected]

Councilor Dr. Doris I. Lewis 236 Lexington Street, Newton, MA 02466 (P) 617-573-8546 (F) 617-573-8668 [email protected]

Councilor Dr. Patricia A. Mabrouk Department of Chemistry, Northeastern University, Boston, MA 02115 (P) 617-373-2845 (F) 617-373-8795 [email protected]

Councilor Pamela Nagafuji Temp. Address: 7431 Ward Ave., El Cerrito, CA 94530-4154 [email protected]

Councilor Dr. Dorothy J. Phillips 10 Lamplight Circle, Natick, MA 01760 (P) 508-482-2860 (F) 508-482-3100 [email protected]

Councilor Dr. Donald O. Rickter 88 Hemlock Street, Arlington, MA 02474 (P) 781-643-7575 [email protected]

61 Councilor Dr. Michael Singer Sigma-RBI, 1 Strathmore Road, Natick, MA 01760 (P) 508-651-8151 x291 (F) 508-655-1359 [email protected]

Councilor Dr. Amy Tapper 182 Beacon St., #11, Boston, MA 02116 (H) 617-421-1986 [email protected]

Alternate Councilor Ms. Eva B. Chenail Wyeth Research, 200 Cambridge Park Drive, Cambridge, MA 02140 (P) 617-665-5646 [email protected]

Alternate Councilor Dr. Michael Filosa 18 Tamarack Road, Medfield, MA 02052-1816 (P) 781-386-8479 [email protected]

Alternate Councilor Dr. Timothy B. Frigo Advanced Magnetics, Inc., 61 Mooney Street, Cambridge, MA 02138 (P) 617-497-2070 (F) 617-547-2445 [email protected]

Alternate Councilor Dr. Mark Froimowitz 90 Eastbourne Road, Newton, MA 02459-1206 (P) 617-732-2851 [email protected]

Alternate Councilor Dr. Patrick M. Gordon 1 Brae Circle, Woburn, MA 01801-2222 (P) 781-932-0169 [email protected]

Alternate Councilor Dr. Barney Grubbs Chemistry Dept., Dartmouth College, Hanover, NH 03755 (P) 603-646-33519096 [email protected]

Alternate Councilor Dr. Jerry P. Jasinski Chemistry Dept., Keene State College, Keene, NH 03435 (P) 603-358-2563 [email protected]

Alternate Councilor Dr. Mukund S. Chorghade 14 Carlson Circle, Natick, MA 01760 (P) 508-651-7809 (F) 508-651-7920 [email protected]

Alternate Councilor Dr. David Cunningham P. O. Box 851, No. Andover, MA 01845 (H) 617-840-8300 [email protected] 62

Alternate Councilor Dr. Julia Miwa Chemistry Dept., Wellesley College, Wellesley, MA 02481-8203 (P) 781-283-3128 (F) 781-283-3642 [email protected]

Alternate Councilor Dr. S. B. Rajur 5 Keystone Way Andover, MA 01810 (P) 781-938-1122 : [email protected]

Alternate Councilor Dr. Lawrence T. Scott Chemistry Department, Boston College, Chestnut Hill, MA 02467 (P) 617-552-8024 [email protected]

Alternate Councilor Dr. Liming Shao Sepracor, Inc., 85 Waterford Drive, Marlborough, MA 01752 (P) 508-357-7468 [email protected]

Alternate Councilor Dr. Alfred Viola 14 Glover Road, Wayland, MA 01778 (P) 508-358-7222 [email protected]

Director-at-Large Dr. Cassandra Celatka Genzyme, 153 Second Street, Waltham, MA 02451 (P) 781-434-3540 [email protected]

Director-at-Large Dr. Ernest V. Groman 80 Columbia Street., Brookline, MA 02446 (P) 617-738-8501 [email protected]

Director-at-Large Dr. Myron S. Simon 20 Somerset Road, West Newton, MA 02465-2722 (P) 617-332-5273 [email protected]

Director-at-Large Stephen Lantos 22 McTernan Street, Cambridge, MA 02139 (P) 617-491-3637 (F) 617-730-2635 [email protected]

Director-at-Large Dr. Gary R. Weisman Dept. of Chemistry, University of New Hampshire, Durham, NH 03824 (P) 603-862-2304 [email protected]

63 Archivist Dr. Myron S. Simon 20 Somerset Road, West Newton, MA 02465-2722 (P) 617-332-5273 [email protected]

Awards Chair Dr. Michael J. Dube Nye, Inc., P. O. Box 8927, New Bedford, MA 02742-8927 (P) 508-996-6721 (F) 508-997-5285 [email protected]

Board of Pubs. Chair Dr. Mary A. Mahaney 12 Commonwealth Avenue, Dedham, MA 02026-1435 (P) 617-577-5541 [email protected]

Budget Chair Dr. James U. Piper 19 Mill Road, Harvard, MA 01451 (P) 978-456-8622 (F) 978-456-8949 [email protected]

Chem. Ed. Chair Dr. Ruth Tanner Department of Chemistry, University of Massachusetts Lowell, Lowell, MA 01854 (P) 978-934-3662 (F) 978-934-2013 [email protected]

Const./Bylaws Chair Dr. Catherine Costello B. U. School of Medicine, 715 Albany Street R-806, Boston, MA 02118-2394 (P) 617-638-6490 (F) 617-638-6491 [email protected]

Continuing Ed. Chair Dr. Alfred Viola 14 Glover Road, Wayland, MA 01778 (P) 508-358-7222 [email protected]

Corporate Funding Dr. Dorothy J. Phillips 10 Lamplight Circle, Natick, MA 01760 (P) 508-482-2860 (F) 508-482-3100 [email protected]

Esselen Chair Mr. Joseph A. Lima 11 Morningside Avenue, Natick, MA 01760 (P) 617-244-5764 (F) 617-254-2713 [email protected]

Local Arrangements Miss Mary Burgess 63 Weld Hill Street, Boston, MA 02130-4150 (P) 617-522-9165 [email protected]

Med. Chem. Rep. Dr. S. B. Rajur 5 Keystone Way, Andover, MA 01810 (P) 978-764-7068 [email protected]

64 Med. Chem. Rep Dr. Liming Shao Sepracor, Inc., 85 Waterford Drive, Marlborough, MA 01752 (Q) 508-357-7468 [email protected]

Membership Chair Mrs. Michaeline Chen 529 Grove Street, Needham, MA 02492 (P) 781-235-5201 [email protected]

NCW Chair Dr. Christine Jaworek-Lopes Emmanuel College, 400 The Fenway, Boston, MA 02115 (P) 617-264-7614 [email protected]

NERM Chair Dr. Morton Z. Hoffman Chemistry Department, Boston University, Boston, MA 02215-2507 (P) 617-353-2494 (F) 617-353-6466 [email protected]

Nominations Chair Dr. Mukund S. Chorghade 14 Carlson Circle, Natick, MA 01760 (P) 508-651-7809 (F) 508-651-7920 [email protected]

Norris Award Chair Dr. Barry Snider Dept. of Chemistry MS015, Brandeis University, Waltham, MA 02254 (P) 781-736-2559 (F) 781-736-2516 [email protected]

Nucleus / Editor Dr. Michael Filosa 18 Tamarack Road, Medfield, MA 02052-1816 (P) 781-386-8479 [email protected]

Prof. Relations/ Dr. Mukund S. Chorghade Career Service 14 Carlson Circle, Natick, MA 01760 (P) 508-651-7809 (F) 508-651-7920 [email protected]

Program Chair Dr. E. Joseph Billo 13 Shattuck Street, Natick, MA 01760 (P) 508-653-3074 [email protected]

Project SEED Chair Dr. Patricia A. Mabrouk Department of Chemistry, Northeastern University, Boston, MA 02115 (P) 617-373-2845 (F) 617-373-8795 [email protected]

Richards Medal Chair Dr. Gary R. Weisman Dept. of Chemistry, University of New Hampshire, Durham, NH 03824 (P) 603-862-2304 [email protected]

65 Senior Chemists Chair Mr. Charles J. Bardsley 61 Harrison Avenue, Braintree, MA 02184-4911 (P) 781-843-6604 [email protected]

Webmaster Dr. David Cunningham P. O. Box 851, No. Andover, MA 01845 (H) 617-840-8300 [email protected] , YCC Chair Laila Dafik Chem. Dept., Tufts University, 62 Talbot Ave., Medford, MA 02155 (P) 617-627-2558 [email protected]

NESACS CALENDAR OF ACTIVITIES - 2008

Date Activity

January 10 Monthly Meeting - Holiday Inn, Brookline Dr. Hannah Sevian, University of Massachusetts Boston Topic: Toward an Inquiry Lab Curriculum in General Chemistry: Can Changing a Single LaboratoryExperiment Improve Student Performance? January 2008 Call for Nominations: Philip L. Levins Memorial Prize for Graduate Students January 2008 Call for Nominations: J. F. Norris Award for Outstanding Achievement in the Teaching of Chemistry February 14 Monthly Meeting - Simmons College, Boston Joint meeting with NOBCChE Dr. Joyce P. Foster, Williams College / Dr. Valerie P. Wilson, Brown University Topic: Mentoring Matters across the Diverse Populations in the Academy March 2008 Call for Nominations: Norris-Richards Undergraduate Summer Research Scholarships March 2008 Call for Papers: Northeast Student Chemistry Research Conference March 2008 Call for Nominations: 2008 Northeast Regional Awards March 13 Monthly Meeting - Harvard Faculty Club, Cambridge Richards Medal Award Meeting Prof. Robert G. Bergman, University of California, Berkeley Topic: Selective Organic and Organometallic Transformations Mediated by Molecular And Supramolecular Environments April 2008 Call for Papers: Northeast Student Chemistry Research Conference (NSCRC) April 9 12th Annual AndrewH. Weinberg Memorial Lecture, Dana Farber Cancer Institute, Boston April 17 Monthly Meeting - Harvard University Gustavus John Esselen Award Dr. John A. Katzenellenbogen, University of Illinois at Champaign-Urbana Topic: Estrogens ad Estrogen Receptors as a Nexus of Chemistry and Biology in Health & Disease April 24 Northeast Student Chemistry Career Fair, Holiday Inn, Brookline May 2008 NESACS Elections conducted; ballots due by June 1 May 8 Monthly Meetng / Education Awards - Northeastern University Prof. Angela Belcher, M. I. T. Topic: From Nature and Back Again . . . Giving new life to materials for energy, electronics, And the environment Presentation of Awards: Philip L. Levins Memorial Prize 66 Norris/Richards Undergraduate Research Fellowships Undergraduate Grants-in-Aid Project SEED Certificates Richards Secondary Teaching Awards Aula Laudis Society - Induction of Members Ashdown Examination Prizes Simmons College Prize Phyllis A. Brauner Memorial Book Award May 2008 Call for Sponsors & Players: 4th Annual Golf Tournament May 14 Medicinal Chemistry Symposium (8:15 a.m. - 5:00 p.m.) Topic: Cost, Speed, and Quality: Eerging Opportunities for Drug Discovery in Asia Speakers: Liming Shao, Sepracor, Marlboro, MA Introductory Remarks Raj Rajur, Ph.D., CreaGen BioSciences, Chair Aravind y Merwade, Ph.D., Wockhardt Ltd., Aurangabad, India Chemistry & Medicinal Chemistry Outsourcing Michael Song, Ph.D., Beijing Pharma-Science Bring Value to Its Customers: A Chinese Startup CRO’s Approach Xiaodong Wang, Ph.D., PharmaAdvance The Next Wave of Outsourcing in Pharmaceutical Industry and How to Prepare for The Paradigm Shift Keynote: Ge Li, Ph.D.,Wuxi PharmaTech, Shanghai, China Steve Tam, Ph.D., Wyeth, Chair June 25 Golf Tournament - Butternut Farm Golf Club, Stow, MA Summer 2008 NESACS Election Results published Summer 2008 Call for Applications: Lyman C. Newell Grants for Secondary Teachers to attend NEACT Conference Summer 2008 James Flack Norris Award Recipient announced / Prof. David K. Gosser, Jr., Prof. Jack A. Kampmeier, And Prof. Pratibha Varma-Nelson Summer 2008 Norris-Richards Undergraduate Summer Research Scholarships awarded to four sudents August 9 Summerthing: Lowell Spinners (Red Sox Single A) vs. Hudson Valley Renegades (Tampa Bay Single A) Pawtucket Red Sox (Red Sox Triple A) vs. Charlotte Knights (White Sox Triple A) August 2008 NESACS is finalist in 5 ChemLuminary Categories Committee on Community Activities--NCW Best High School Event Committee on Community Activities--Outstanding Event for a Specific Audience Committee on Local Section Activities--Best Activity or Program Stimulating Membership Involvement Committee on Local Section Activities--Outstanding Performance by a Local Section Very Large Size Category Younger Chemists Committee--Outstanding or Creative Local Section Younger Chemists Committee Event September 2008 Call for Nominations: Gustavus John Esselen Award for Chemistry in the Public Interest September 2008 Call for Applications: Grants-in-Aid to Undergraduates to attend 2009 National Meeting / Salt Lake City September 11 Monthly Meeting – Joint meeting with Medicinal Chemistry Group Medicinal Chemistry Group Symposium – Merkert Chemistry Center, Boston College Topic: New Developments in Anti-Infective Research Moderator: Dr. Norton Peet, International R&D Consultant, No. Andover, MA. Speakers: John Williams, Senior Research Investigator, Microbiotix, Worcester, MA Nucleosides and the Challenge of Antivirals: ZSM-I-62 as a Candidate Anti-HCMV Drug Gregory S. Bisacchi, Associate Director, AstraZeneca R&D Boston Antibacterial Discovery: Past, Present and Future Milind Deshpande, Executive Vice President & Chief Scientific Officer, Achillion Pharmaceuticals, New Haven, CT 67 Isothiazolopyridones and Isothiazoloquinolones: Discovery of Potent Antibacterial Agents forTreatment of Highly Drug-Resistant Pathogens October 2008 Call for Applications: YCC/NESACS--JCF/GDCh Exchange to Germany - 2009 October 2007 Call for Abstracts: 7th Annual New England Environmental Research Symposium October 2008 Annual Nucleus Buyers Guide published in Nucleus October 18 Monthly Meeting – Northeastern University/Henderson House - Weston, MA Henry A. Hill Award for Outstanding Service to the Northeastern Section to Dr. Michael Singer 50-Year Members of ACS presented certificates of recognition Dr. Peter Meltzer, President, Organix, Inc., Woburn, MA Topic: The Establishment and Evolution of a Small Chemical Business in Massachusetts October 2008 National Chemistry Week Activities Sept 1-Oct 15 - K-12 Poster Competition Oct. 18 - Museum of Science Boston Phyllis A. Brauner Memorial Lecture by Dr. Bassam Shakhashiri Kicking off NCW 2008 Festivities Oct. 25 - Boston Children’s Museum Demonstrations and hands-on activities related to the yearly theme Oct. 1-31 - Grades 1-12 puzzle Contest October 16- NCW Connections to Chemistry - High School Teacher Workshop - Burlington (MA) High School Workshop A: Prescribing Success for the Future with Nicole Clark, Clinical Pharmacist, Hallmark Health System Workshop B: The Real CSI Lab with Bill Hebard, Chemist, Mass. State Crime Laboratory Workshop C: “Play Ball” with Parick Drane, Mechanical Engineer & Asst. Director, Baseball Research Center, University of Massachusetts Lowell Workshop D: Let Your Fingers Do the Walking with Liana Lamont, Asst. Editor, Journal of Chemical Education, University of Wisconsin-Madison Dinner Speaker: Thomas H. Lane, President-elect, American Chemical Society Address: . . . And Now for Something Completely Different November 1 15th Annual ACS Northeast Regional Undergraduate Day - Simmons College Keynote Address: Dr. John C. Warner, Warner Babcock Institute for Green Chemistry Research Talks & Panel Discussions Workshops I & II Student Affiliates Workshop November 13 Monthly Meeting / Brandeis University Faculty Club James Flack Norris Award Dinner & Program Prof. David K. Gosser, City College of New York Prof. Jack A. Kampmeier, University of Rochester Prof. Pratibha Varma-Nelson, Indiana University-Purdue University Award Recipients and Speakers Topic: “Peer-led Team Learning” November 20-21 Two-Day Short Course: Laboratory Health & Safety Northeastern University, Boston November 15 Seventh Annual Environmental Research Symposium / Bridgewater State College Co-sponsored by NESACS with Bridgewater State College December 2008 Call for Nominations - Norris Award (Outstanding Achievement in the Teaching of Chemistry) December 2008 Call for Nominations - Levins Memorial Prize (Graduate Student) December 10 Monthly Meeting – Joint meeting with Medicinal Chemistry Group Medicinal Chemistry Group Symposium – Holiday Inn Select Hotel, Woburn, MA Topic: New Technologies for Drug Discovery Moderator: Dr. Norton Peet, International Consultant, No. Andover, MA Speakers: John A. Porco, Jr., Professor & Director, Boston University Chemical Methodology and Library Development Center, Boston, MA New Approaches for Discovery o Chemical Reactions and Chemotypes Scott L. Harbeson, Vice President, Research, Concert Pharmaceuticals, Inc., Lexington, MA 68 Selective Deuterium Chemistry in Drug Discovery: Improved New Chemical Entities from Clinically Validated Therapeutics Christopher G. Newton, Senior Vice President, BioFocus DPI, Essex, UK Drug Discovery in the 21st Century - the Collaborative Paradigm

REPORT OF THE ARCHIVIST - 2008 Myron S. Simon, Ph.D., Archivist

Having resigned two summers ago, I am still puttering along, waiting for some ambitious and historically inclined young enthusiast to take my place. I have continued to hold the position, but at a low level of activity.

The Archives continue to be stored in the basement of the library at Regis College. The incoming Chair of the Section has offered to find a more pleasant place for them to be kept, as bait to keep up my efforts.

I am somewhat behind in collecting and filing the reports of meeting of the Board of Directors. I have been elected to the position of Director at Large, and find that my biggest contribution may be that of bringing the Archives up to date.

This year I have given talks at the Esselen Award meeting and the Norris Award meeting on the lives of the named men. I find this to be a pleasant opportunity to look back to the times when they flourished, even though my talks each year are very little different from the talks of the year before, and before that.

We filled a request from Ina Wanschura, librarian of the Max Planck Institute for the Chemistry and Physics of Solid Materials at Dresden, for an article which appeared in our Nucleus in the 60’s, which was a little different from the usual requests.

We received a copy of the Memorial Booklet from the ACS meeting in Boston-Swampscott in 1928. It was found on the shelves of the UOP library by the librarian, Laura Claggett, and given us. We have been using the biographies of Noted New England Chemists which it contains as a serial feature in the Nucleus..

Respectfully submitted,

Myron S. Simon, Ph.D. Archivist, NESACS

REPORT OF THE AWARDS COMMITTEE - 2009 Michael J. Dube, Chair

The responsibility of the Awards Committee for NESACS includes the presentation of two awards issued by the Section. These awards include the Henry A. Hill Award and the Phillip Levins Prize.

The former is awarded to a member of the Northeastern Section for meritorious service. This year the award was presented to Dr. Michael Singer. This award was presented at the October local section meeting.

69 The Levins Prize is awarded to a graduate student demonstrating superior achievement. This year, the award was given to Chengjun Wang from the University of Massachusetts Dartmouth under the direction of Dr. Yuegang Zuo

Respectfully submitted, Michael J. Dube, Ph.D. Chair, NESACS Awards Committee

NORTHEASTERN SECTION

of the

AMERICAN CHEMICAL SOCIETY

Presentation of the

Twenty-ninth

HENRY A. HILL MEMORIAL AWARD for Outstanding Contribution to the Northeastern Section

to

Michael Singer

Wednesday, October 15 Two thousand eight Henderson House Weston, MA 70

PROGRAM E. Joseph Billo Chair-elect Northeastern Section, presiding

RECOGNITION OF FIFTY-YEAR MEMBERS

Presentation of 50-Year Certificates...... E. Joseph Billo

THE HENRY A. HILL AWARD

Welcome ...... E. Joseph Billo

Presentation of the Hill Award ...... Michael J. Dube Chair, NESACS Awards Committee

Henry A. Hill Award...... Anthony Cromwell Hill

Acceptance...... Michael Singer

ADDRESS Dr. Peter Meltzer President, Organix, Inc., Woburn

"The Establishment & Evolution of a Small Chemical Business in Massachusetts”

PRIOR RECIPIENTS of the HENRY A. HILL MEMORIAL AWARD for Outstanding Contribution to the Northeastern Section

Henry A. Hill (posthumously)...... 1980 Edward R. Atkinson ...... 1981 Robert D. Eddy...... 1982 Arnet L. Powell (posthumously) ...... 1983 G. Richard Handrick...... 1984 Janet S. Perkins...... 1984 Phyllis A. Brauner...... 1985 71 Arno H. A. Heyn ...... 1986 Sr. Magdalen Julie Wallace (posthumously) ...... 1987 Esther A. H. Hopkins...... 1988 Wallace J. Gleekman ...... 1989 James U. Piper ...... 1990 Valerie Wilcox...... 1991 Ernest I. Becker ...... 1992 Arlene W. Light ...... 1993 Truman S. Light ...... 1993 William O. Foye ...... 1994 Michael E. Strem ...... 1995 Alfred Viola...... 1996 Mary T. Burgess ...... 1997 Michaeline F. Chen...... 1997 David M. Howell ...... 1997 John L. Neumeyer...... 1998 Morton Z. Hoffman ...... 1999 Catherine E. Costello...... 2000 Myron S. Simon ...... 2001 Michael J. Hearn...... 2002 Doris I. Lewis...... 2003 Donald O. Rickter...... 2004 Charles E. Kolb...... 2005 Dorothy J. Phillips ...... 2006 Ruth Tanner...... 2007

Henry Aaron Hill

This month we are honoring the memory of Henry A. Hill by giving awards in his name to one of our Section members for meritorious service to the Northeastern Section.

Who was Henry A. Hill?

Henry Hill was Chairman of our Section in 1963 and president of the American Chemical Society in 1976. He was very active in the national ACS, and served as a member of and chairman of several of its committees. His service on the Professional Relations Committee was especially notable where he drafted the Professional Employment Guidelines. He was Director of the ACS in 1971-1975, was elected President-elect and became President in 1976.

Born in St. Joseph, Missouri, he obtained a bachelor's degree from Johnson C. Smith University. With the help of his son, writer Tony Hill, we have a better understanding of his career . Here is what Tony wrote:

"Following his graduation from Johnson C. Smith College, my father was somewhat adrift. Due to his role in a student protest (that was quite mild by the standards of our generation), my father was precluded from beginning his graduate education immediately because officials at JCS refused to release his transcripts in a timely manner. He moved to Chicago where he lived with his eldest brother, Tony, before securing admission to the University of Chicago the following year. However, he was shortly given to understand that under the quota system then operative at Chicago, as well as other major universities, a mistake had been made in admitting both him and another black student, Warren Henry, and that only one of them would be allowed to continue his studies at Chicago after their first year. Although my father earned better grades than did Warren Henry, not to mention a number of their white classmates, it was Henry and not my dad who was offered the opportunity to continue his studies at Chicago.

"Stymied, my father was prepared to give up his studies in chemistry, but Tony was determined to have his brother 72 enabled to pursue his dream. Learning that the president of MIT was scheduled to speak in Buffalo, Tony drove through a blizzard to Buffalo, buttonholed the president of MIT in the lobby of the hotel at which he was staying, and pressed the case for his brother's admission. As a result of this intervention and, of course, my father's stellar grades, he was admitted to MIT, where his experience was as the biographical statement relates."

He was accepted at M.I.T. to study organic chemistry. He obtained the Ph.D. in 1942 working under Professor Robert C. Hockett with the highest grades of the graduate students in his class. While at M.I.T., he became acquainted with Professor James Flack Norris of whom he said:

’He was the first big man I met who was more interested in my ability to learn chemistry than in the identity of my grandparents.’ Tony writes:

"However, following his graduation at the top of his doctoral class, my father applied to 33 companies for a position as a chemist without success. At the urging of James Flack Norris, he remained undeterred and applied to Atlantic Research, a fledgling outfit founded by another of Norris's proteges, Francis Atwood. In 1943, Atwood hired my father to work on the development of an anti-tank weapon, a burning jelly that would eventually become known as napalm."

(I don’t know whether Atwood had been contracted by Professor Fieser or not, but I have to recall when I was in graduate school the smoky fires outside a laboratory at Harvard where Professor Lou Fieser was devising and testing napalm.) . Hill and a few colleagues established a small consulting business. In 1946 he joined Dewey & Almy Co. as Research Supervisor, and in 1952 he became Vice President of National Polychemicals which was active in polymer chemistry. He obtained patents for blowing agents.

In 1961 he established his own research and consulting business, Riverside Laboratories, to be able to pursue his research interests and to allow him to participate in ACS activities. Riverside Research was not just a research and consulting business but also a manufacturing company that supplied blowing agents to a variety of clients here and abroad.

After his untimely death in 1979, friends and colleagues in the Northeastern Section established the Henry A. Hill Award for Outstanding Service to the Northeastern Section. The first award was made posthumously to Henry A. Hill in 1980; his son, Anthony C. Hill, then a reporter for WGBH, accepted the award. Since then, thirty members of this Section have been thus honored and thereby honored the memory of Henry A. Hill.

This biography was from an appreciation of Henry A. Hill delivered by Arno Heyn at the 1991 Hill Award meeting and based on notes of the late Larry Powell as well as recent valuable additions by Tony Hill.

Honored Members

AMERICAN CHEMICAL SOCIETY

Members - Fifty Years

Alice J. Adler Richard N. Macnair Kenneth K. Andersen Norman E. Mahoney Maurice L. Arel Stephen J. Miller Maria L. Bade Thomas L. O’Connor Shelton Bank Peter Ofner 73 Howard S. Bender Gerald M. Olderman Robert Berman Myrna S. Pearson Rudolf G. Brautigam John T. Peniston Thomas J. Curphey Charles H. C. Pian Henry O. Daley, Jr. David V. Ragone Elisabeth M. Drake Miguel A. F. Refojo David W. Ellis Andre Rosowsky William Eykamp Marlowe Sigal Harvey George Roger Soderberg John Gergely Mary Ann Solstad Jack M. Goldstein Kenneth Speigel Norman J. Hochella Stephen J. Stepenuck Marcus Karel Ray D. Taylor Marvin L. Kronenberg Alfred J. Valcourt Horst G. Langer Theodore T. Wall Jerome F. Levy Richard L. Young

74

75 Invitation to 50-Year Members

NORTHEASTERN SECTION AMERICAN CHEMICAL SOCIETY

ADMINISTRATIVE SECRETARY PHONE OR FAX 23 COTTAGE STREET (508) 653-6329 NATICK, MA 01760 MA AND NH ONLY E-MAIL: [email protected] (800) 872-2054

September 16, 2008

Line 1 Line 2 Line 3

Salutation:

Congratulations on your fifty years of membership in the American Chemical Society. I would like to take this opportunity to commend you on your longevity and continued association with chemistry. This is a very important milestone and we of the Northeastern Section would like to celebrate with you.

At the October meeting of the Northeastern Section, in addition to presenting the Hill Award, we will be honoring our fifty-year members. I hope that you (and a guest) will be able to attend as guests of the Section so that we can congratulate you personally. We are also interested in learning about your career in chemistry. If you would like to do so, we would appreciate receiving a brief biographical sketch that can be added to the archives of the Northeastern Section. It can be sent to the Section office at the address or e-mail shown in the letterhead.

You should already have received a 50-year member lapel pin and a 50-year membership card that entitles you to free registration at ACS National and regional meetings. These were sent to you earlier this year directly from the national office of the American Chemical Society.

The meeting is on Wednesday evening, October 15, at the Henderson House in Weston, MA. Additional information and further details of the program for the evening are provided on the enclosed flyer and will also appear in the October issue of The Nucleus. Please contact Marilou Cashman in the Section office by October 8 to make your dinner reservations. She may be reached by phone at (800) 872-2054 or by e-mail at [email protected].

Again, my congratulations and thanks for your many years of service.

Sincerely,

Marietta Schwartz, Chair Northeastern Section, ACS

76 Flyer for October meeting:

The Establishment & Evolution of a Small Chemical Business in Massachusetts Dr. Peter Meltzer President, Organix, Inc., Woburn, MA

Wednesday – October 15, 2008 Henderson House 99 Westcliff Road - Weston, MA 02493 - (781) 235-8517

5:30 pm Social Hour 6:15 pm Dinner 7:15 pm Evening Meeting – Dr. Marietta Schwartz, NESACS Chair presiding _ Presentation of Certificates to 50-Year Members of ACS _ Henry A. Hill Award for Outstanding Service to the Northeastern Section presented to Dr. Michael Singer _ Speaker: Dr. Peter Meltzer

Dinner reservations should be made no later than 12:00 noon on Wednesday, October 8, 2008. Please contact Marilou Cashman at (800) 872-2054 or (508) 653-6329 or [email protected]. Reservations not canceled at least 24 hours in advance must be paid. Members, $28.00; Non-members, $30.00; Retirees, $15.00; Students, $10.00. Anyone who needs handicapped services, please call a few days in advance so that suitable arrangements can be made.

DIRECTIONS • Going West on Route 30 1 mile west of intersection of Rt. 128 & 30 Take a left onto Oak St. (Oak St. becomes Cliff Rd) Go straight through 4-way intersection Take second right, onto Scotch Pine Rd. Take first right onto Westcliff Rd. Henderson House is the first house on the left • Going Route 128 North or South Take Exit 24 and follow Rt. 30 West directions • Going north on Route 128 Take Exit 20B and follow Rt. 9 West directions • Going west on the Massachusetts Turnpike Take Exit 15 to Rt. 30 West Follow Rt. 30 West directions • Going east on the Massachusetts Turnpike Take Exit 14 Rt. 128 Take the exit for Rt. 30 at Rt. 128 (Exit 24) Follow Rt. 30 west directions • Going west on Route 9 2 miles west of Rt. 128, to set of lights (By Fire Station) Go through lights, take first right onto Cliff Rd. Take the 7th left onto Scotch Pine Rd. Take first right onto Westcliff Rd. Henderson House is the first house on the left. • Going east on Route 9 2 miles past Wellesley town line sign Take a right off Rt. 9 onto Rt. 16 Go west on Rt. 16 to 1st set of lights Take right at lights onto Cliff Rd. Take the 7th left onto Scotch Pine Rd. Take your first right onto Westcliff Rd. Henderson House is the first house on the left

THE PUBLIC IS INVITED

77

AWARDS PRESENTED BY THE NORTHEASTERN SECTION, ACS

James Flack Norris Award Dennis A. Dougherty California Institute of Technology in Physical Organic Chemistry (presented at ACS National Meeting)

Gustavus John Esselen Award Dr. John A. Katzenellenbogen University of Illinois for Chemistry in the Public Interest at Urbana-Champaign

James Flack Norris Award Dr. David K. Gosser, Jr. City College of New York for Outstanding Achievement in the Dr. Jack A. Kampmeier University of Rochester Teaching of Chemistry Dr. Pratibha Varma-Nelson Indiana University-Purdue University

Henry A. Hill Award Dr. Michael Singer Sigma-Aldrich for Outstanding Service to the Northeastern Section, ACS

Arno H. A. Heyn Memorial Book Award Vivian Walworth NESACS Board of Publications

Induction into the Aula Laudis Society Paul Cernota Phillips Academy, Andover, MA Faith Hughes Barnstable H.S., Hyannis, MA Valerie Lechtanski Hopkinton (MA) H.S. George Goodfellow New Bedford (MA) H.S. / retired

Philip L. Levins Memorial Prize Chengjun Wang University of Massachusetts Dartmouth

Norris-Richards Undergraduate Summer Alexander Gitlin Harvard College Research Scholarships Devon Heath Stonehill College Derek Kong Tufts University Samuel Beal Wheaton College

Undergraduate Grants-in-Aid Certificates Kevin Robbins Keene State College Jeffrey Garber Dartmouth College Jonathan Doran University of Massachusetts Dartmouth

Dr. Phyllis A. Brauner Jeffrey Garber Dartmouth College Memorial Book Award

Project SEED Certificates with Stonehill College Mentor Sabianca Delva Randolph High School Dr. Louis Liotta Nurbaity Faris Randolph High School

Ashdown Examination Awards: First Place / Simmons College Prize Simon H. Ye Andover H.S. Second Place Adhvait M. Shah Burlington H.S. Third Place Isaac O Bleicher Newton North H.S. Fourth Place (tie) Noah Arbesfeld Lexington H.S. Christopher Teng Lexington H.S. Joshua R. Infantine Phillips Academy Tully Cheng Wayland H.S.

Honorable Mention - 1st-year Students Josh Leung Lexington H.S. Kyumin Lee Lexington H.S. Kenneth E. Tharp Phillips Academy 78 David Storch Arlington H.S. Ramanjit Singh Arlington H.S. Randy X. Li Phillips Academy.

Honorable Mention - 2nd-year Students Rebecca Wang Acton-Boxborough H.S. Alexander J. Woolf Newton North H.S. Greg Silva Acton-Boxborough H.S. Lorcan McGonigle Groton School Ian F. Tenney Commonwealth School Paul O’Neil Concord-Carlisle H.S.

AWARDS & HONORS RECEIVED BY NESACS MEMBERS FROM OTHER ORGANIZATIONS

Student Affiliate Chapter - Simmons College Faculty Advisor: Dr. Richard Gurney ACS Recognition - Commendable

Student Affiliate Chapter - Suffolk University Faculty Advisor: Dr. Doris Lewis ACS Recognition - Outstanding

Joanna Aizenberg - Harvard University ACS Award: Ronald Breslow Award for Achievement in Biomimetic Chemistry 79

Eric N. Jacobsen - Harvard University ACS Award: Herbert C. Brown Award for Creative Research in Synthetic Methods

Patrick Cappillino - Boston University Graduate Student 3rd Place Award / Oral Presentation 10th Young Scientists Conference on Chemistry University of Rostock, Germany

Shuyu Wang - Harvard University Student Poster Presentation 10th Young Scientists Conference on Chemistry University of Rostock, Germany

Robert Langer - M.I.T. 2008 Millennium Technology Prize Technology Academy Finland

Steve Lantos - Brookline (MA) High School ACS CHED Northeast Region Award Excellence in High School Teaching

Christine Jaworek-Lopes - Emmanuel College ACS Northeast Region Award Excellence in Volunteer Services

To be awarded at ACS meetings in 2009:

Daniel G. Nocera - M.I.T. ACS Award in Inorganic Chemistry (Aldrich Chemical)

Mohammad Movassaghi - M.I.T. Arthur C. Cope Scholar Award

Cynthia M. Friend - Harvard University George A. Olah Award in Hydrocarbon or Petroleum Chemistry

John L. Neumeyer Director of Medicinal Chemistry Program McLean Hospital / Harvard Medical School And Professor Emeritus - Northeastern University Inducted into American Chemical Society Hall of Fame

80

81

REPORT OF THE PHYLLIS A. BRAUNER MEMORIAL LECTURE COMMITTEE - 2008 Doris I. Lewis, Chair

Members of the Phyllis A. Brauner Memorial Lecture Committee in 2008 were: Inka Allen Chris Jaworek-Lopez Ruth Tanner Steven Allen Dudley Hershbach Ann Jenkins Bassam Shakhashiri Catherine Brauner Doris I. Lewis Carolyn Spodick Susan Brauner Esther A. H. Hopkins Julianna Lovell

As agreed by the Northeastern Section and the ACS, the Phyllis A. Brauner Lecture is held in the Northeastern Section’s territory in conjunction with National Chemistry Week and named in memory of Dr. Brauner. As envisioned and established by Phyllis, and presented by the Northeastern Section since 1986, the Lecture will be for the general public of all ages. The endowment goal is a $140,000 endowment fund with income supporting the lectures.

Subcommittees met throughout the year to organize experiment preps, to organize volunteer activities, and to coordinate activities with the Museum of Science. Activities of the Committee this year were centered around organizing the 2008 Phyllis A. Brauner Lecture with the NCW theme Having a Ball with Chemistry. This year once more the lecturer was Bassam Shakhashiri, presenting chemical demonstrations; the popular lecture was presented to capacity audiences in the morning and afternoon totaling over 500.In honor of this year being the 50th anniversary of his coming to the United States, in Boston, Bassam Shakhashiri was presented with a Salutes to Excellence Award preceding the morning lecture. This year again the Museum of Science offered to host The Brauner Lecture and associated activities, an especially appropriate site since Phyllis Brauner was active in promoting joint activities with NESACS and the Museum of Science. The Northeastern Section web site www.nesacs.org features the National Chemistry Week activities. Activities for the day were led by over forty undergraduate volunteers from local colleges along with other Northeastern Section , and are described in the National Chemistry Week report by Chair Chris Jaworek-Lopez.. Dave Sittenfield of the Museum prepared the reagents and technical arrangements for the Lecture, assisted by Steve and Inka Allen on the day of the lecture. Doris Lewis, and Joe Ciuryla of Suffolk University also assisted in the Lecture activities. This year new form of survey was conducted, as we participated in a computer-based interactive assessment by “survey monkey.”

This year once more a long-time objective of the Brauner Lecture Committee was realized. With the aid of a grant from Merck and an ACS Innovative Projects Grant, we were able to expand the Lecture to a Monday presentation in addition to the Sunday lectures. We had observed that whether the venue was at Wellesley or in the city at the Museum of Science, the audience was mainly composed of relatively affluent families from the suburb, and the Lecture was not reaching inner-city student populations. The partnership with the Museum made this possible, as they were able to use their outreach to city schools to bring school groups to Dr. Shakhashiri’s lecture.

Susan Brauner arranged radio advertising on WBUR in conjunction with the NPR Science Friday show.. With the aid of Cathy Brauner the Brauner Lectures were also featured in the Wellesley Townsman.

The proposed bylaw amendments to the NESACS constitution incorporating the Brauner Committee into the constitution and submitted in November 2006 have yet to be reviewed by the national ACS C & B Committee.

82 On 12/31/08 the Brauner Memorial Lecture account contained cash and investments totaling $22,320.17. The Brauner share of the Consolidated Account was $28,215.21, so the total value is in excess of $50,000. During the year, $2000 was transferred to the Section operating account to reimburse 2007 expenses. On 12/31 there was $9888.47 in cash in the account, of which $3555.03 was principal and the remainder was income.

The account currently owes the Section operating account $2000 for the 2008 honorarium.

Below, Dr. Shakhashiri, Susan Brauner, and Doris Lewis “Having a Ball with Chemistry” NCW 2009 Phyllis A. Bruner Memorial Lecture

83 REPORT OF THE COMMITTEE ON AMENDMENTS TO THE CONSTITUTION & BYLAWS 2008 Catherine E. Costello, Chair

The committee was composed of the following members: Catherine Costello, Chair Esther Hopkins Doris Lewis Truman Light Myron Simon Michael Singer

The Board of Directors of the Northeastern Section is presently considering the modification of the Constitution and Bylaws of the Section to introduce an award in honor of Phyllis Brauner, a former Section chair who contributed significantly to the success of the Section over many years. Additional matters under consideration are a C&B modification that would increase the number of members of the Publications committee and changes that would allow the use of electronic ballots. To become informed and contribute to discussions on the latter matter, committee chair participated in the ACS conference call organized during 2008. Drafts of the changes will be presented to the board for their consideration and the revisions will be sent to the national C&B for comment before a vote by section members is scheduled.

Catherine E. Costello Chair, NESACS C&B Committee Contact person: Prof. Catherine E. Costello Center for Biomedical Mass Spectrometry Boston University School of Medicine 670 Albany Street, Rm 511 Boston, MA 02118-2646 phone: 617-638-6490 fax: 617-638-6491 e-mail: [email protected]

NORTHEASTERN SECTION - COMMITTEE ON CONTINUING EDUCATION 2008 Annual Narrative Report

Since 1993, when we learned that National ACS had decided to make ACS Short Courses available to local sections at tuition fees greatly reduced from the normal fee structure currently in excess of $1,200, this Committee had sponsored Short Courses under this aegis. Since our original offering in 1993 was a highly successful event, the Committee continued to bring such courses to the Northeastern Section. In accord with tradition in recent years, the Committee had intended to schedule two events in 2008. However, with the retirement of Harry Walsh, Head of National’s Continuing Education Office, a new Department Head was appointed and new innovative programs were initiated. Among these was one which sent a cluster of courses to various locations apart from any National or Regional meetings. In the spring of 2008 several courses were sent to a Boston location, which negated the opportunity to offer any such course under the aegis of NESACS.

In the fall, the committee decided to offer the two-day Short Course: Laboratory Health and Safety, presented through the “Laboratory Safety Institute” located in Natick, MA. Its director, Dr. James Kaufman, a member of NESACS, presented an earlier version of this course in 1997.

84 Dr. Kaufman is also a former ACS National Lecturer who founded the Institute to devote himself full- time to this topic. National ACS does not bring its own course on Laboratory Safety into the Boston area in deference to its former association with Dr. Kaufman.

Probably due to current economic conditions, course enrollments were disappointingly small and the seven registrants were readily accommodated in the Conference Room of the Institute, which also provided food for breakfasts and coffee breaks free of charge.

85 Chemists Celebrate Earth Day 2008 Submitted by Christine Jaworek-Lopes

On April 22, 2008, NESACS partnered with the Massachusetts Bays Estuary Association (MBEA) and the Malden High School Chemistry Club for a daylong event at the Boston Children’s Museum. More than 2000 individuals visited the museum that day. The MBEA provided an Enviroscape Model and demonstrated how pollutants from our homes ultimately end up in our water supply. Children used spray bottles to simulate rain and wash away the waste products (food coloring and spices).

In addition, the MBEA provided water samples from two Massachusetts bays. The Malden High School Chemistry Club showed visitors to the museum how to colorimetrically test for pH, water hardness, nitrates, iron, and phosphates in these water samples. In addition, visitors to the museum could test the pH of common household items such as soda and orange juice. Finally, the Malden High School Chemistry Club demonstrated water hardness by adding detergent to samples of hard water and soft water. Children and adults alike were amazed by the difference in lathering ability of these two extremes. The Section participated in the CCED Haiku competition. A total of eight entries were received (four from grades 9-12; one from grades 3-5; three from grades K-2) from three different schools. Each student that submitted a winning haiku for CCED was given a certificate of achievement as well as an Earth Day t-shirt. The teachers of these students received one of the following ACS publications: Apples, Bubbles, and Crystals – Your Science ABCs or Real World Cases in Green Chemistry.

EDUCATION COMMITTEE Submitted by Ruth Tanner, Chair 2008 Report

Education Committee Members

Ruth Tanner, Chair Undergraduate Programs Stephen Lantos High School Subcommittee Chair Morton Hoffman Professor Emeritus of Chemistry, Boston University. Robert Lichter ACS Scholars

The Education Committee supports and promotes academic program activities that showcase chemical education and young chemists at both the high school and college/university levels. Through announcements at the monthly meetings of the Section, in The Nucleus, and via mailings, information is provided to the membership in order to foster a greater interest in chemical education and to develop a responsible professional outlook toward chemistry among young scientists.

The Chair of the Education Committee, Ruth Tanner, is a chemistry faculty member at the University of Massachusetts Lowell. The Chair of the High School Subcommittee, Stephen Lantos, is a chemistry faculty member at Brookline (MA) High School. The ACS Scholars program is coordinated by Robert Lichter, Principal, Merrimack Consultants, LLC.

James Flack Norris/Theodore William Richards Undergraduate Summer Research Scholarships. (Edwin Jahngen, University of Massachusetts Lowell, Chair).

The Northeastern Section of the American Chemical Society (NESACS) established the James Flack Norris and Theodore William Richards Undergraduate Summer Scholarships to honor the memories of

86 Professors Norris and Richards by promoting research interactions between undergraduate students and faculty. Research awards of $3250 were given for the summer of 2008. The student stipend is $2750 for a minimum commitment of ten weeks of full-time research work. The remaining $500 of the award goes to the research advisor to use on supplies, travel, and other items relevant to the student project.

The 2008 scholarships were awarded to:

Derek Kong, Tufts University, Understanding P8 and PELP: Stress Induced Transcriptional Coregulators of Matrix Metalloprotease-9 in Heart Disease, Krishna Kumar, Advisor Samuel Beal, Wheaton College, Chemical Weathering in the Hydrological System of the Greenland Ice Sheet, Evans Matthew, Advisor Devon Heath, Stonehill College, Synthesis of 1,1,1-trifluoro-4-trimethylsilyl-2-butanone-3,3-d2: Beta- Deuterium Isotope Effects of Electron-Deficient Gamma-Silyl Cations, Leon Tilley, Advisor Alexander Gitlin, Harvard College, Molecular Regulation and Modulation of Beta Cell Identity and Function, Stuart Schreiber, Advisor

Award winners were required to submit a report of their summer projects by November 2008 for publication in The Nucleus. They are also required to participate in the Northeast Student Chemistry Research Conference (NSCRC) in May 2009.

The scholarships were publicized through The Nucleus, the NESACS Web site, and mailings of applications and descriptive material to the chairs of the Departments of Chemistry, Biochemistry, and Chemical Engineering at colleges and universities in the Section. Applications included student transcripts, descriptions of the proposed research, and two letters of recommendation. The awards enabled the students to spend the summer of 2008 engaged in research at their home institutions.

Fifteenth Annual Northeast Regional Undergraduate Day (Coordinated by Richard Gurney and Hosted by the Chemistry/Physics Liaison at Simmons College)

The 15th annual Northeast Regional Undergraduate Day sponsored by the Education Committee was held on November 1, 2008 at Simmons in conjunction with National Chemistry Week Activities. The registrants represented colleges and universities from Massachusetts, Rhode Island, Connecticut, New Hampshire, Ohio(Baldwin-Wallace College) and Vermont. The keynote address Green Chemistry: Designing a sustainable future with beakers and flasks was given by Dr. John Warner from the Warner Babcock Institute for Green Chemistry

The program included the seminars, panel discussions, a graduate school/industry fair, and laboratory workshops:

Seminars: Nolan T. Flynn, Wellesley College An REU-based research group and metal nanoparticles: Controlling assembly at different length scales Matthias Brewer, University of Vermont, The discovery of a novel ring fragmentation reaction and its application in heterocyclic synthesis Ryan Hayward, University of Massachusetts, Instabilities of polymers at interfaces: New routes to complex and responsive materials Margaret Kerr, Worcester State College, An international Green Chemistry Experience: Insight into the Fulbright Scholarship Program for Students and Faculty Chris Larson, University of Oregon. The Industrial Internship Masters Program at the University of Oregon 87

Panel Discussions: Applying to Research Experiences for Undergraduates (REU) Programs Applying to Graduate School Ph.D. Programs

Workshops Student Affiliate Workshop, Beyond Benign Hydrolysis of post-consumer polylactic acid Extraction of D-limonene using liquid carbon dioxide Construction of dye-sensitized solar cells using blackberry juice Using biodiesel glycerin byproduct to produce soap

The graduate school and industry fair provided students with the opportunity to obtain information from representatives of universities and industries. It also provided resume’ review by industrial representatives. A nominal registration fee was charged to offset the costs of refreshments, lunch and materials.

The Seventh Undergraduate Environmental Research Symposium. Sponsored by the Education Committee of the Northeastern Section ACS et al., and Coordinated by Edward Brush et al from Bridgewater (MA) State College (BSC).

The Education Committee of NESACS co-sponsored the Seventh Annual Undergraduate Environmental Research Symposium held on Saturday, November 15, 2008 at Bridgewater State College. The symposium focuses on undergraduate and graduate research projects, with a special emphasis on environmental issues of particular concern to Southeastern Massachusetts. This Symposium provides an annual forum for discussion of environmental research conducted by undergraduate students in the New England region, and has opened doors to potential research collaborations among the participants.

The Symposium ran from 9:00 AM to 3:00 PM and featured 54 poster presentations from undergraduate researchers representing colleges and universities from the New England region. Over 100 students, faculty and mentors were in attendance. The welcoming remarks were given by BSC Dean of the School of Arts and Sciences, Dr. Rita Miller. She was followed by two speakers on the theme “Water: Regional and Global Issues”: • Dr. Ellen Douglas, Department of Environmental, Earth and Ocean Sciences, University of Massachusetts Boston, Issues in Water Resources from New England to the Globe • Dr. Kevin Curry, Department of Biology, Bridgewater State College, One Filter at a Time: Health and Pure Water for Cambodia

The poster sessions began immediately following the seminars, running from 11:00 – 2:30. The complete program with all presenters, titles and abstracts can be accessed from the symposium web page: http://www.bridgew.edu/Environmental/PDF%20docs/2008%20Complete%20Brochure.pdf Attendees completed an evaluation form to help the organizers improve the current format, and plan for new and expanded initiatives. Funding by NESACS was acknowledged. In addition to NESACS, financial assistance was provided by the Bridgewater State College Adrian Tinsley Program for Undergraduate Research and by the NCUR/Lancy Initiative, a program that provides resources to undergraduates who show promise of exceptional achievement. The 8th Annual Environmental Research Symposium is tentatively scheduled for Saturday, November 14, 2009.

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The Northeast Student Chemistry Research Conference (X). Sponsored by the Education Committee of the Northeastern Section ACS and the Younger Chemists Committee of the Northeastern Section

Held at the Massachusetts Institute of Technology on April 19, 2008, the tenth annual Research Conference brought together undergraduates, graduates students and postdoctoral fellows from the northeastern region of the country for the purpose of celebrating their accomplishments in research, and for providing a forum for the sharing of ideas and scientific understanding. The keynote address, Small- Molecule Probe and Drug Discovery was given by Professor Stuart Schreiber of Harvard University.

Thirty-eight poster presentations are given by undergraduate students, graduate students, and post- doctoral fellows. In addition to the research poster presentations, there were 8 student presentations: 4 undergraduate student speakers and 4 graduate student speakers. The presenting students and their institutions were:

Mark Chen (MIT) Polyisoprene Specificity in N-linked Glycosylation Patrick Ng (Northeastern University) Methodology for the Preparation of PET Imaging Ligands Sanghamitra Mitra (Boston University) Impact of Sequence and Structure on the Redox Properties of Thioredoxin and Glutaredoxin Darin Bellisario (Tufts University) Temperature Effects on the Formation of Dialkyl Sulfide Self- Assembled Monolayers on Au(III) Shuyu Wang (Harvard University) AlkA in Action: X-ray Crystallography of a DNA Repair Glycosylase with Unusually Broad Substrate Specificity Jeffrey Garber (Dartmouth College) Amphiphilic Block Copolymers Precursors to Cobalt Polymer Hybrids Erin Iski (Tufts University) AgCl Monolayers on Au (III): Novel, Ultra-stable and Atomically-flat surfaces Carl Christianson (Boston College) Probing the mechanism of a tyrosine 2, 3-aminomutase from enediyne natural product biosynthesis

Following the presentations, awards were given for the outstanding speaker and outstanding poster presentations. In addition, a presentation of the NESACS Phyllis Brauner* Undergraduate Book Award was made to Jeffrey Garber from Dartmouth University for his excellent oral presentation of his research paper given above. *Dr. Phyllis Brauner received a PhD in Analytical Chemistry from Boston University and was a Distinguished Alumnae. She was a Faculty member at Simmons College for 34 years while at the same time making significant contributions to NESACS thru the many committees she served on, including serving as the Chair of the Board of Directors. She had a fascination with nature and had a passion to pass on that fascination thru chemistry to young people. She inspired her students to love chemistry and to recognize their special role as chemists in society.

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Grants -in -Aid to Undergraduates (Subcommittee: Ruth Tanner, Martin Isaks)

The Education Committee awarded Grants-in-Aid of $350 each to undergraduates at colleges and universities within the Northeastern Section to enable them to attend the 237th ACS National Meeting in Salt Lake City, Utah to present a paper at the Undergraduate Research Poster Session in the Division of Chemical Education on Monday, March 23, 2009. Matching funds have been committed by the awardees’ institutions to support the students’ travel. The recipients are also required to participate in the Northeast Student Chemistry Research Conference (NSCRC) in April 2009.

The awardees, their research supervisors, and the titles of their papers are as follows:

Daniel Abbott, Framingham State College, (Prof. Catherine Dignam) Design and Synthesis of New Chiral Diketimine Complexes for Asymmetric Catalysis Natalie Dogal, Stonehill College (Prof. Louis Liotta) 3-(hydroxymethyl)hexahydro-1H-pyrrolizine- 1,2,6,7-tetraol synthesis from D-glucose Henry Kells, University of Massachusetts Lowell (Prof. Daniel Sandman) Polymerization of Ethynylpyridines with Electrophilic Carbohydrate Reagents

Applications for the travel stipend are accepted from students majoring in chemistry, biochemistry, chemical engineering, or molecular biology who are in good standing with at least junior status, and are currently engaged in undergraduate research. . CONNECTIONS TO CHEMISTRY (Ruth Tanner, Chair)

Program Conference Committee: Ruth Tanner, Chair, Education Committee, NESACS; University of Massachusetts Lowell Morton Hoffman, Professor Emeritus, Boston University; 2005 Chair of CHED Steve Lantos, Chemistry Faculty, Brookline (MA) High School

Planning and Program Associates: Christine Jaworek, Chair, National Chemistry Week, NESACS; Emmanuel College Peter Nassiff, Past-Chair, NEACT; Head, Science Division, Burlington High School Arthur Fallon, Head, Media Services, Burlington High School Mark Malagodi, Computer Services, Burlington High School Paul Virgin. Coordinator of Food Services, Burlington High School Nancy Spicer, Biochemist, Sepracor, Inc. Martin Isaks, Chemistry Faculty, University of Massachusetts Lowell James Hall, Director of Freshman Laboratories, University of Massachusetts Lowell Marilou Cashman, Executive Secretary for NESACS.

Material Assistance John Moore, Editor, Journal of Chemical Education Linda Fanis, Assistant Editor, Journal of Chemical Education Jamie Warren, ChemMatters, ACS Marilou Cashman, Executive Secretary, NESACS The Connections program received substantial material assistance from the ACS, and the editorial staff of the Journal of Chemical Education . 90

Publicity Support New England Association of Chemistry Teachers (NEACT) Massachusetts Association of Science Teachers (MAST) University of Massachusetts Lowell The Nucleus (NESACS)

On October 16, 2008 NESACS sponsored Connections to Chemistry, a unique program to connect high school chemistry teachers to the educational resources of the ACS and to the members of the Northeastern Section. This is the ninth year for the program. Hosted by Burlington (MA) High School, the program drew over 110 teachers from 76 different high schools in Massachusetts, New Hampshire, Connecticut, Rhode Island, and Maine.

The high school chemistry teachers were welcomed to the program by Ruth Tanner (University of Massachusetts Lowell), Chair of the NESACS Education Committee and Chair of the Connections to Chemistry program; by Steve Lantos, Chair of the High School Education Committee; and by Dr. Thomas Lane, Chair-Elect, ACS. The participants were encouraged to utilize the ACS CHED resources, to consider affiliate membership in the Division of Chemical Education via the new Chemistry Teacher Connection (CTC) program, and of course, to become active in starting a high school chemistry club affiliated with the ACS.

Following the opening, four simultaneous workshops were offered in two sessions to showcase the ACS resources for high school chemistry teachers and students:

Prescribing Success for the Future: Nicole Clark, Intensive Care Clinical Pharmacist, Hallmark Health System The Real CSI Lab: Bill Hebard, Chemist; and Andrea Wilson, Forensic Chemist, Massachusetts State Crime Laboratory “Play Ball”, National Chemistry Week: Patrick Drane, Assistant Director, Baseball Research Center, University of Massachusetts Lowell Let Your Fingers Do the Walking: Liana Lamont, Assistant Editor, Journal of Chemical Education, Department of Chemistry, University of Wisconsin–Madison University

The evening program included dinner and a keynote address And Now for Something Completely Different by Dr. Thomas Lane, Chair-Elect, American Chemical Society, and Director of Global Science and Technology Outreach at Dow Corning Corporation. Following his address, several items were raffled, including American Chemical Society items (mugs and laser pen pointers), subscriptions to the Journal of Chemical Education (2 of which, were donated by the Journal) memberships in CHED (donated by CHED), and memberships in CTC (Chemistry Teacher Connection). In addition, Thomas Lane donated four VISA cards to the raffle each worth $100.00. To conclude the program, participants were given a certificate awarding professional development credits, a year’s subscription to ChemMatters, and a year’s associate membership in the Northeastern Section of the ACS.

ACS SCHOLARS PROGRAM (Robert Lichter, Chair)

This is the eighth year for the involvement of the NESACS in the ACS Scholars Program. The NESACS sponsored one student, Jose Barcena, a chemistry major at MIT.

In the 2008 calendar year, 21 Scholars were studying within NESACS:

91 College Chemistry Massachusetts Institute of Technology Chemistry Harvard University Chemistry Massachusetts Institute of Technology Chemical Engineering Massachusetts Institute of Technology Chemical Engineering Massachusetts Institute of Technology Chemical Engineering Massachusetts Institute of Technology Chemical Engineering Franklin W. Olin College of Engineering Chemical Engineering Massachusetts Institute of Technology Chemical Engineering Massachusetts Institute of Technology Chemistry & Physics Harvard University Chemical Engineering Northeastern University Chemistry & Environmental Science Harvard University Biochemistry Tufts University Materials Science & Engineering Massachusetts Institute of Technology Materials & Mechanical Engineering Harvard University Biochemistry Wellesley College Chemical Engineering Massachusetts Institute of Technology Engineering Massachusetts Institute of Technology Chemical Engineering Massachusetts Institute of Technology Chemistry Northeastern University Chemical Engineer Massachusetts Institute of Technology

In continuing efforts to build connections with the ACS Scholars in the NESACS area, all of these Scholars are contacted by e-mail monthly from September to May, and informed of NESACS activities of interest to undergraduates. In particular, they were invited to attend the monthly meetings of the Section, and to be its guests at the social hours and dinners that preceded the invited speakers. The additional advantages are for the Scholars to meet each other and to encourage them to think about ways for the Section to help them achieve their academic and career goals. They also were put on the mailing list to receive THE NUCLEUS.

YCC/NESACS–JCF/GDCh German Exchange (Michael Strem, Strem Chemicals, Chair, Ruth Tanner, Morton Hoffman, and YCC Members.

The Younger Chemists Committee (YCC) of the Northeastern Section and the NESACS Education Committee co-sponsored an exchange of students to Germany March 25 – April 2, 2008 which included undergraduate and graduate students. This was a continuation of the German Exchange program of the NESACS.

The trip included a student chemistry research conference (Frühjahrssymposium) in Rostock on Thursday-Saturday, March 27-29, which provided the opportunity for the participants to engage in extensive networking with German and other European students, and to take part in discussions focused on careers, education, and international opportunities. On Sunday-Tuesday, March 30-April 1, excursions to industrial, academic, scientific, and cultural institutions in and around Hamburg were be scheduled. Each student representative from NESACS gave a presentation of either a poster or oral presentation on his/her research at the Frühjahrssymposium, and also upon return gave the poster or oral presentation at 92 the Northeast Student Chemistry Research Conference (NSCRC) on Saturday, April 26. Air tickets were provided by NESACS; accommodations in Germany were covered by GDCh. A working knowledge of German, while useful, was not specifically required; the language of the Frühjahrssymposium and the other events was in English.

(Most of the information reported above for the Exchange Program appeared in the group’s report to THE NUCLEUS, the NESACS monthly publication.) A detailed report will also be given in the yearly report from the Younger Chemists’ Committee of NESACS.

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EDUCATION COMMITTEE High School Subcommittee Stephen Lantos, Subcommittee Chair

High School Subcommittee Members Stephen Lantos, Chair Peter Nassiff Avery A. Ashdown Examination Ruth Tanner Lyman C. Newell Grants David Olney Aula Laudis Society Stephen Lantos Theodore William Richards Award

Avery A. Ashdown High School Chemistry Examination Contest & U.S. Chemistry Olympiad Team (Ashdown Committee: Peter Nassiff, Chair; Steve Lantos (Olympiad Section Coordinator: Steve Lantos)

The HS Education Committee continues to sponsor and run the annual Avery Ashdown High School Examination Contest. Since the early 1970s, the exam seeks participation from nearly 40 schools across the section with over 100 students sitting annually for the exam each spring. Cash prizes are awarded to the top five scorers; honorable mention certificates are given to the students earning the top five scores at each of the two levels--first and second year. Peter Nassiff will continue to head the exam writing and administration of the Ashdown Exam. Top scorers from the exam are eligible to participate in the United States National Chemistry Olympiad. We hope that increased participation and awareness of these competitive chemistry exams will allow NESACS to send one of our students to the 2009 International Chemistry Olympiad.

The Northeastern Section continues to pilot the new ACS High School Chemistry Clubs program, now in its third year. We encourage interested teachers across the section to consider starting an ACS-sponsored Chemistry Club in their school. For details, please contact Steve Lantos. We’re in the midst of advertising

94 and initiating these programs within our section and have received a positive response from the Section’s high school chemistry teachers.

United States Chemistry Olympiad Team (Section Coordinator: Steve Lantos) The Section administers the National etc…….. The 2008 Avery Ashdown Chemistry Exam was held on Saturday, April 5 at Simmons College. Ninety- nine students participated from 26 schools around the section. The Simmons College Prize ($500) was awarded to Simon H. Ye from Andover High School. The Northeastern Section was allotted 26 seats for students from our section to take the United States National Chemistry Olympiad (USNCO), held at Simmons College on April 19. Unfortunately, none of our students qualified to go forward to the study camp at the US Air Force Academy to prepare for the International Chemistry Olympiad (IChO). Maybe in 2009 . . .

2008 Ashdown Examination Awards: First Place / Simmons College Prize Simon H. Ye Andover H.S. Second Place Adhvait M. Shah Burlington H.S. Third Place Isaac O Bleicher Newton North H.S. Fourth Place (tie) Noah Arbesfeld Lexington H.S. Christopher Teng Lexington H.S. Joshua R. Infantine Phillips Academy Tully Cheng Wayland H.S.

Honorable Mention - 1st-year Students Josh Leung Lexington H.S. Kyumin Lee Lexington H.S. Kenneth E. Tharp Phillips Academy David Storch Arlington H.S. Ramanjit Singh Arlington H.S. Randy X. Li Phillips Academy.

Honorable Mention - 2nd-year Students Rebecca Wang Acton-Boxborough H.S. Alexander J. Woolf Newton North H.S. Greg Silva Acton-Boxborough H.S. Lorcan McGonigle Groton School Ian F. Tenney Commonwealth School Paul O’Neil Concord-Carlisle H.S.

Lyman C. Newell Grants Ruth Tanner, Chair

The Lyman C. Newell Grants provide financial assistance to high school teachers in the geographical area of the Northeastern Section of the ACS to subsidize the cost of attending the annual summer conference sponsored by NEACT, the New England Association of Chemistry Teachers. The grants are administered by the Newell Grants Committee. The Committee administers the grant process starting with the publicity to the awarding of the grants. The Committee coordinates its activities with the Chair of the Education Committee and the President of NEACT.

95 The Northeastern Section of the American Chemical Society awards a maximum of four grants of $225.00 to partially cover the cost of the conference. This year’s conference was the 70th NEACT Summer Conference. The title of the conference was Nano-Fibers, High Tech Textiles, and Structural Color, held from August 4-7, 2008 at the University of Massachusetts, Dartmouth, MA

The four-day conference gave participants opportunities to work in the lab, to design new activities, and to view demonstrations. The program is co-sponsored by NEACT and the Department of Chemistry at the University of Massachusetts Dartmouth.

The Lyman C. Newell Grants commemorate a former chair of the Northeastern Section who was a distinguished chemist, teacher, and historian of chemistry. For many years he was chair of the Chemistry Department at Boston University. Lyman Newell served as the first president of NEACT from 1889 to 1900 and expressed a continuing interest in training chemistry students throughout his long career. His efforts are continued by grants that bear his name.

Aula Laudis Society (Committee: Dave Olney, Chair; Kathleen Skelly, Helen O’Keefe)

The Section recognizes outstanding secondary school teachers of chemistry by naming them to the Aula Laudis Society at the Annual Education Awards Night conducted in May. In 2008, four area teachers were inducted into the Society; i.e., Paul Cerota Phillips Academy, Andover, MA Faith Hughes Barnstable High School, Hyannis, MA Valerie Lechtanski Hopkinton High School, Hopkinton, MA George Goodfellow Retired/New Bedford H.S.

Theodore William Richards Award (Committee: Steve Lantos, Chair, Emily Dudek, Christopher Doona, Martin Idelson) The Theodore William Richards Award for Excellence in Teaching of Secondary School Chemistry was not awarded in 2008

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97 98

SAMPLE FORMS USED IN HIGH SCHOOL AND COLLEGE MAILINGS / WEB POSTINGS

Call for Papers – Grant-in-Aid Program

Call for Papers

Undergraduate Research Poster Session

at the

237th National Meeting of the American Chemical Society Salt Lake City, Utah March 22-26, 2009

The ACS invites undergraduate students to submit abstracts of their research papers for presentation at the Undergraduate Research Poster Session (URPS), which will be part of the extensive programming for undergraduates at this national meeting. Submit your abstract electronically by October 20, 2008 (11:59 pm EST) to . Click on the CHED division and then select the URPS site that is appropriate to the subject of your paper. Please follow the directions carefully.

For further information, contact:

Nancy Bakowski ACS Student Affiliates Program 1155 Sixteenth Street, NW Washington, DC 20036 Tel: (800) 227-5558, ext. 6166 e–mail: [email protected]

99 Grant-in-Aid Letter to Winners

NORTHEASTERN SECTION AMERICAN CHEMICAL SOCIETY ADMINISTRATIVE SECRETARY PHONE OR FAX 23 COTTAGE STREET (508) 653-6329 NATICK, MA 01760 MA AND NH ONLY E-MAIL: [email protected] (800) 872-2054

October 22, 2008

Line 1 Line 2 Line 3 Line 4 Line 5

Salutation:

On behalf of the Northeastern Section of the American Chemical Society (NESACS), I want to take this opportunity to congratulate you as a recipient of a Grant-in-Aid of $350 to enable you to attend the 237th National Meeting of the American Chemical Society in Salt Lake City, Utah, and to present a paper at the Undergraduate Research Poster Session in the Division of Chemical Education. It will be your responsibility to arrange for your own transportation and housing at the meeting; details about the meeting will be given in Chemical & Engineering News in the course of the next several months.

A check from NESACS will be sent to you at your campus address after the presentation of your poster at the ACS meeting that will take place from March 22 - March 26, 2009. If your address changes before then, please notify me. At least $350 has been committed for your travel by your institution; you should consult with the chairperson of your department about this portion of your travel funds.

As a recipient of this award, you are also required to present your poster at the Northeast Student Chemistry Research Conference (NSCRC) to be held in April, 2009. You will receive more information about this event in due course. To honor your award further, you and your research advisor will be invited to be guests of the Section at the NESACS Education Night in May.

I congratulate you on your achievement, and look forward to seeing you and your poster in Salt Lake City. I wish you good luck on your research project, and in your continued study of chemistry.

Sincerely yours, Dr. Ruth Tanner, Chair NESACS Education Committee

100 Call for Applications

The James Flack Norris and Theodore William Richards Undergraduate Summer Research Scholarships The Northeastern Section of the American Chemical Society (NESACS) established the James Flack Norris and Theodore William Richards Undergraduate Summer Scholarships to honor the memories of Professors Norris and Richards by promoting research interactions between undergraduate students and faculty.

Research awards of $3250 will be given for the summer of 2008. The student stipend is $2750 for a minimum commitment of ten weeks of full-time research work. The remaining $500 of the award can be spent on supplies, travel, and other items relevant to the student project.

Institutions whose student/faculty team receives a Norris/Richards Undergraduate Summer Research Scholarship are expected to contribute toward the support of the faculty members and to waive any student fees for summer research. Academic credit may be granted to the students at the discretion of the institutions.

Award winners are required to submit a report (~5-7 double-spaced pages including figures, tables, and bibliography) of their summer projects to the NESACS Education Committee by November 3, 2008 for publication in THE Nucleus. They are also required to participate in the Northeast Student Chemistry Research Conference (NSCRC) in April 2009.

Eligibility: Applications will be accepted from student/faculty teams at colleges and universities within the Northeastern Section. The undergraduate student must be a chemistry, biochemistry, chemical engineering, or molecular biology major in good standing, and have completed at least two full years of college-level chemistry by summer, 2008.

Application: Application forms are available on the NESACS web site at http://www.nesacs.org. Completed applications are to be submitted no later than April 4, 2008 to the Chair of the Selection Committee:

Professor Edwin Jahngen University of Massachusetts Lowell Chemistry Department, Room 520, Olney Hall 1 University Avenue Lowell, MA 01854-5047

Notification: Applicants will be notified of the results by e-mail on April 23, 2008 with written confirmation to follow.

101 Informational Letter – Summer Research Scholarships

NORTHEASTERN SECTION AMERICAN CHEMICAL SOCIETY

ADMINISTRATIVE SECRETARY PHONE OR FAX 23 COTTAGE STREET (508) 653-6329 NATICK, MA 01760 MA AND NH ONLY E-MAIL: [email protected] (800) 872-2054

February 7, 2008

To: Chairpersons of Departments of Chemistry, Chemical Engineering, and Biochemistry (Colleges and Universities in the Northeastern Section of the American Chemical Society)

From: Professor Ruth Tanner (University of Massachusetts Lowell), Chair Education Committee of the Northeastern Section of the American Chemical Society

Subject: Applications for Norris/Richards 2008 Undergraduate Summer Research Scholarships

The Northeastern Section of the American Chemical Society (NESACS) established the James Flack Norris and Theodore William Richards Undergraduate Summer Scholarships to honor the memories of Professors Norris and Richards through the promotion of research interactions between undergraduate students and faculty. Research awards of $3,250 will be given for the Summer of 2008, which include a stipend to the student of $2,750 for a minimum of ten weeks of full-time research work; the remaining $500 can be spent on supplies, travel, and other items related to the student project. I am asking for your help to make sure that all those student/faculty pairs who might be interested in applying for support are informed of this program. The deadline for receipt of the completed applications (with two supporting letters) is April 4, 2008. Applicants will be notified of the results on April 23, 2008. Completed application must be submitted to the Chair of the Selection Committee: Professor Edwin Jahngen University of Massachusetts Lowell Chemistry Department, Room 520 1 University Avenue, Olney Hall Lowell, MA 01854-5047

Enclosed is an announcement of the program. I ask you to distribute and post it where students and faculty will see it. I would also appreciate your help in making sure that students who might qualify for the scholarships, but who are majors in departments not covered by this mailing, have an opportunity to obtain the information.

Institutions whose student/faculty team receives a Norris/Richards Fellowship are expected to contribute toward the support of the faculty member and to waive any student fees for summer research. Academic credit may be granted to the students at the discretion of the institutions. Award winners are required to submit a report of their summer projects by November 3, 2008, for publication in The Nucleus, and to participate in the NESACS Northeast Student Chemistry Research Conference in April 2009.

Application forms are available on the NESACS web site at http://www.nesacs.org. If you, your students, or your faculty have any questions about the program or the application, call me at (978) 934-3662, or contact Professor Edwin Jahngen, Chair of the Selection Committee at (978) 934-3693.

Thank you for helping to make this program known and for promoting undergraduate research as a vital part of chemical education.

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NORRIS-RICHARDS NOTIFICATION LETTER NORTHEASTERN SECTION AMERICAN CHEMICAL SOCIETY

ADMINISTRATIVE SECRETARY PHONE OR FAX 23 COTTAGE STREET (508) 653-6329 NATICK, MA 01760 MA AND NH ONLY E-MAIL: [email protected] (800) 872-2054

April 22, 2008

Student address

Salutation

CONGRATULATIONS!

I am pleased to inform you that you have been selected to receive a 2008 James Flack Norris / Theodore William Richards Summer Research Scholarship. This award carries a stipend of $2750 for a minimum commitment of ten weeks of full-time summer research. Another $500, to be spent at the discretion of your research advisor, is available for faculty support, supplies, travel, and other items relevant to the project.

You will receive one-half of the stipend at the award ceremony on May 8. The second half will be sent to your research advisor around July 1. You are required to submit a report of your summer work to me (Chemistry Department, Olney Hall, 265 Riverside Street, Room 520, University of Massachusetts Lowell, Lowell, MA 01854- 5047) by November 3, 2008 for publication in The Nucleus. This report should be ~5-7 double-spaced typed pages, including figures, tables, and bibliography. Upon my receipt of your report, the $500 for the support of your research will be released to your advisor. In addition, you are to present your work at the Northeast Student Chemistry Research Conference (NSCRC) tentatively scheduled for Saturday, April 18, 2009. You will receive reminders of these obligations.

The presentation of the award to you will be made at the 888th meeting of the Northeastern Section on Thursday, May 8, at Northeastern University. A flyer is enclosed providing additional information. You are cordially invited to be the guest of the Northeastern Section for the social hour and dinner starting at 5:15 p.m. The award presentations will be preceded by a talk by Prof. Angela Belcher of M.I.T. whose talk is entitled “From nature and back again . . . Giving new life to materials for energy, electronics and the environment.“ Your research advisor has also been invited to the dinner as a guest of the Northeastern Section.

Should your parents or friends desire to attend, the cost of the dinner is $30.00 ($10.00 for students). Please respond by e-mail, phone or fax to the Section Office by noon on May 1 to confirm your attendance and make any additional reservations. If you prefer a vegetarian meal, please indicate so when making your reservation(s). A message may be left on the tape if no one is in the office when you call.

I extend my congratulations to you and look forward to seeing you on May 8. I wish you a very productive summer of research.

Sincerely yours,

Dr. Ruth Tanner, Chair NESACS Education Committee 103 Informational Letter – Ashdown Exam

Northeastern Section AMERICAN CHEMICAL SOCIETY

ADMINISTRATIVE SECRETARY PHONE OR FAX 23 COTTAGE STREET (508) 653-6329 NATICK, MA 01760 MA AND NH ONLY E-MAIL: [email protected] (800) 872-2054

TO: High School Chemistry Teachers FROM: Steve Lantos, Chair, High School Education Committee DATE: February 22, 2008

NOTE: Please refer to the website of the Northeastern Section for Ashdown Examination information and registration forms. The URL is http://www.nesacs.org

This year's Avery Ashdown High School Chemistry Examination Contest of the Northeastern Section of the American Chemical Society will take place on SATURDAY, APRIL 5, starting at 9:00 a.m. at SIMMONS COLLEGE 300 The Fenway

Boston, MA 02115 The entrance to the Park Science Building (where the exams will be) is on Louis Pasteur Blvd.

At Simmons, we will be using rooms in the Science Building which is directly behind the Main College Building. Because of construction, on-campus parking may not be available. We are currently in the process of arranging for parking on April 5 and 19; as soon as this has been finalized, the information will be posted on the website of the Northeastern Section, ACS, at www.nesacs.org. Student participants in the exam and teachers or parents accompanying the students are strongly encouraged to use public transportation or to share rides to Simmons if public transportation is not available in your area.

Each high school in the Northeastern Section may be represented by a maximum of five (5) participants selected by their school or teachers for each exam.. (One alternate may be named on the registration form, but only five students will be tested.) Winners of cash awards in previous years are not eligible to compete for Ashdown recognition; however, they may compete to become eligible for the Olympiad Examination. Cash awards will be given to the students with the top five (5) scores. Honorable mention awards will be given to five (5) first-year and five (5) second-year students with the next highest scores. In addition, each winning student will be invited, along with his/her teacher, to be guests of the Northeastern Section at its May 8, 2008, dinner meeting and will be given appropriate recognition. SCORES WILL BE REPORTED TO TEACHERS VIA E-MAIL IF ADDRESSES ARE PROVIDED ON THE TEACHER REGISTRATION FORM.

Top scorers in the Ashdown Examination will be eligible to take the qualifying exam for the Unites States Chemistry Olympiad Team on April 19. PLEASE SEE THE GUIDELINES ON THE REVERSE SIDE OF THIS MEMO FOR MORE INFORMATION ABOUT THE ASHDOWN EXAMINATION AND THE INTERNATIONAL CHEMISTRY OLYMPIAD.

Please return the enclosed STUDENT and TEACHER REGISTRATION FORMS by Tuesday, April 1, 2008, to register your students for the Ashdown Exam. Each student should bring #2 pencils to the examination. Students 104 may use programmable or graphing calculators provided the memory is erased from the programs. This will be verified by proctors before the exam.

Along with the enclosed form for registration of students, it is requested that each school send $5.00 per student ($25 maximum) in order to help defray the cost of prizes and awards. The check should be made out to NESACS - Ashdown Exam. (Please DO NOT SEND PURCHASE ORDERS.)

Please be certain that your students make careful note of the exact information about the examination since this is not an official function of the college involved and few on campus will be aware of essential details. Any questions about the details of the examination should be directed, preferably by e-mail, to: Dr. Peter Nassiff Burlington High School Burlington, MA 01803 781-270-2923 e-mail: [email protected] Questions relating to registrations for the exam should be directed to: Marilou Cashman (508) 653-6329 or (800) 872-2054 e-mail: [email protected]

2008 AVERY A. ASHDOWN EXAMINATION GUIDELINES

1. Entrants. The Ashdown Examination has traditionally divided students into two categories: first- year and second-year/AP level. In the past, problems have arisen in defining those students who are taking chemistry as a second-year course but do not follow the AP curriculum and those who are taking a first-year course but do follow the AP curriculum. The Examination Committee’s goal is to test for chemical knowledge rather than to define the academic guidelines of entrants. Thus, students will be classified as first-year (first exposure to chemistry) and second-year (a second-year of chemistry), regardless of a course name, curriculum, or an individual's background. We feel this will most fairly include as many as possible in taking the examination

2. Scoring and Prizes. Five cash prizes will be given for the top scores of ALL entrants. Duplicate scores in the top five will be considered as two of the five scores. Scoring is determined by raw score. The next five scores for both first and second year will be awarded an Honorable Mention and certificate, regardless of duplicate scores. Recognition will also be given to each teacher.

3. The Exam. The examination will be 85 multiple-choice questions. No penalty will be deducted for wrong answers.

4. U. S. National Chemistry Olympiad (USNCO). Those students wishing to compete in the International Chemistry Olympiad (IChO) qualifying examination will be selected from the top scorers. Should there be a duplicate score, both entrants may be considered. Students must be U. S. Citizens by the date of the USNCO. Only two students from any school may compete.

5. Other. Students may use programmable or graphing calculators provided the memory is erased from the programs. Proctors will verify this. Within one week of the exam date, student scores will be mailed or e-mailed to the participating schools notifying teachers of the winners. A breakdown of the

105 range of scores and high scorers will be included along with a distribution of the types of chemistry questions included on this year's examination.

No cellular telephones will be permitted in the examination room. A secure room will be made available at the test site to store phones and bookbags.

Should there be questions about the examination, please contact Dr. Peter Nassiff at (781) 270-2923 or by e-mail to [email protected]. Questions about registrations for the exam should be addressed to the Administrative Secretary by e-mail to [email protected]

Dates

Registration Deadline for Ashdown Examination Tuesday, April 1, 2008 The Ashdown Examination Contest Saturday, April 5 at 9:00 a.m. at Simmons College The Qualifying Olympiad Exam Saturday, April 19 at 9:00 a.m. at Simmons College. The exam will be administered only to the top scorers on the Ashdown Exam. These students will be notified by telephone within a day or two after the Ashdown Exam. NESACS Education Night Awards Dinner Thursday, May 8, 2008 at Northeastern University. (Ashdown Award prizewinners and their teachers will be honored. Note: This information may also be found on the internet at http://www.nesacs.org

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REPORT OF THE ESSELEN AWARD COMMITTEE – 2008 Joseph A. Lima, Chair

The 22nd Gustavus John Esselen Award for Chemistry in the Public Interest was presented on April 17, 2008 to Dr. John A. Katzenellenbogen, Swanlund Professor of Chemistry, University of Illinois at Urbana-Champaign. Dr. Katzenellenbogen was recognized for his contributions to the study of the structure, function and use of steroid receptors. He prepared the first affinity labeling agents for the estrogen receptor and has used them to elucidate receptor structure, function and dynamics. He has developed an extensive series of labeled steroid receptor-based agents for positron emission tomography that have proven to be of great value in detecting malignancies of the breast and prostate while simultaneously providing information on the type of therapy that will be most beneficial to the patient.

The award reception and dinner were held at the Harvard Faculty Club with approximately 80 people in attendance. The award ceremony and recipient’s address, “Estrogens and Estrogen Receptors as a Nexus of Chemistry and Biology in Health and Disease” were held in the Pfizer Lecture Hall in Mallinckrodt Chemistry Building. The award recipient was introduced by Prof. E. J. Corey. The award, consisting of a medal and a check for $5000, was presented to Dr. Katzenellenbogen by Mr. Gustavus John Esselen, IV.

The members of the 2008 Award Committee were: Rudi Baum, C&E News; James Kinsey, Rice University; Charles Kolb, Aerodyne Research; Joseph Lima, Houghton Chemical Corporation; John Neumeyer, McLean Hospital; Arthur Obermayer, Moleculon Research; and Thomas Verhoeven, Eli Lilly Corp.

John Neumeyer will succeed Joseph Lima as Chair of the Esselen Award Committee for 2009, with duties to commence after the Esselen Award events for 2008.

Submitted by, Joseph A. Lima, Chair Esselen Award Committee, 2008

Dr. John A. Katzenellenbogen Esselen Award Recipient - 2008

107 Invitation to Esselen Award Dinner

The Board of Directors of the Northeastern Section of the American Chemical Society requests the honor of your presence on the occasion of the twenty-second presentation of The Gustavus John Esselen Award for Chemistry in the Public Interest to John A. Katzenellenbogen on Thursday, April 17, 2008

5:30 o’clock 8:15 o’clock Preprandial hour and dinner Award ceremonies Harvard Faculty Club Pfizer Lecture Hall 20 Quincy Street Mallinckrodt Chemistry Laboratories Cambridge, Massachusetts 12 Oxford Street Cambridge, Massachusetts Black Tie Optional

Esselen Award Dinner Program

Presentation of the

Twenty-second

GUSTAVUS JOHN ESSELEN AWARD

for

CHEMISTRY IN THE PUBLIC INTEREST

to

JOHN A. KATZENELLENBOGEN

Thursday, April Seventeenth Two Thousand Eight Harvard University Cambridge, Massachusetts

108 JOHN A. KATZENELLENBOGEN Swanlund Professor of Chemistry University of Illinois Urbana-Champaign

John A. Katzenellenbogen received his A.B. degree from Harvard University and his Ph.D. degree for his graduate studies in chemical synthesis with Professor E. J. Corey at Harvard. He then became an Assistant Professor in the Department of Chemistry at the University of Illinois at Urbana-Champaign, where he is currently the Swanlund Chaired Professor of Chemistry.

Dr. Katzenellenbogen is the author of more than 440 research papers and has produced over 100 doctoral and postdoctoral students from his research group. He is a fellow of the American Academy of Arts and Sciences and recipient of several awards including a Cope Scholar Award of the American Chemical Society, the Roy O. Greep Lecture Award of The Endocrine Society (jointly with Benita S. Katzenellenbogen, Swanlund Chaired Professor of Molecular and Integrative Physiology at Illinois), and the E. B. Hershberg Award in Medicinal Chemistry of the American Chemical Society. He has served on the editorial boards of a number of ACS and other journals and is currently an Associate Editor of Steroids and the Journal of Nuclear Medicine.

Dr Katzenellenbogen's research has been directed at the structure, function and use of steroid receptors. He prepared the first affinity labeling agents for the estrogen receptor and used them to study receptor structure, function and dynamics. He has developed an extensive series of steroid receptor-based agents labeled with fluorine-18 and technetium-99m for imaging receptor positive tumors of the breast and prostate by positron emission tomography. These compounds have highly selective activity on the estrogen alpha and beta subtypes and have proven to be of great benefit in not only the detection of malignancies but also in simultaneously indicating the degree to which hormone therapy will be beneficial. He has developed fluorescent probes for steroid receptors that enable receptor dynamics to be followed in individual cells, resulting in commercially available fluorescence polarization assays for estrogen receptor ligand binding. More recently, he has undertaken biochemical and biophysical studies of the estrogen receptor protein and steroid hormone receptor coregulator proteins.

Program

Preprandial Hour and Dinner Harvard Faculty Club

Esselen Award Ceremonies Pfizer Lecture Hall Mallinckrodt Chemistry Laboratories

Chair, Northeastern Section Marietta Schwartz Welcome Joseph A. Lima The Esselen Award Myron S. Simon Introduction of the Awardee E. J. Corey Presentation of the Award Gustavus J. Esselen, IV Esselen Award Address John A. Katzenellenbogen

“Estrogens and Estrogen Receptors as a Nexus of Chemistry and Biology in Health and Disease."

The Esselen Award is made possible through an endowment by the Esselen Family in memory of Dr. Gustavus J. Esselen 109 PRIOR RECIPIENTS OF THE ESSELEN AWARD FOR CHEMISTRY IN THE PUBLIC INTEREST

F. Sherwood Rowland and Mario J. Molina ...... 1987 Discovery of the effect of chlorofluorocarbons on the ozone layer

Alfred P. Wolf and Joanna S. Fowler ...... 1988 Chemical methods used in positron emission tomography for medical diagnostics

Carl Djerassi ...... 1989 Contraception and the synthesis of the first birth control drug

Thomas J. Dougherty ...... 1990 Photodynamic therapy for treatment of malignant disease

Jerrold Meinwald and Thomas Eisner ...... 1991 Insect Chemistry and Human Welfare

Bruce N. Ames ...... 1992 Understanding the Causes of Aging and Cancer

James G. Anderson ...... 1993 Global Ozone Loss and its Prediction

Kary B. Mullis ...... 1994 The Polymerase Chain Reaction

Howard J. Schaeffer ...... 1995 Nucleosides with Antiviral Activity: Discovery of Acyclovir (Zovirax®)

Roy G. Gordon ...... 1996 Low-Emissivity Glass: Energy Conserving Windows

Rangaswamy Srinivasan ...... 1997 Ablative Photo Decomposition for Micromachining of Polymers and Biological Tissue

Kyriacos C. Nicolaou ...... 1998 Chemical Synthesis and Chemical Biology of Natural Substances

Robert S. Langer ...... 1999 The Development of Unique Polymers for Medical Applications

William A. Pryor ...... 2000 Vitamin E and the Prevention of Heart Disease

Joseph M. DeSimone ...... 2001 Green Chemistry for Sustainable Economic Development

Ronald Breslow ...... 2002 Chemistry Lessons from Biology and vice versa

Bruce D. Roth ...... 2003 The Discovery and Development of Lipitor®

James W. Jorgenson...... 2004 The Magic of Capillaries in Chemical Separations and Analysis

Jean M. J. Fréchet ...... 2005 Functional Macromolecules: From Design and Synthesis to Application

Richard D. DiMarchi ...... 2006 Chemical Biotechnology as a Means to Optimal Protein Therapeutics

Michael A. Marletta ...... 2007 Nitric Oxide in Biology: From Discovery to Therapeutics

110 NOMINATIONS SOUGHT

GUSTAVUS JOHN ESSELEN AWARD FOR CHEMISTRY IN THE PUBLIC INTEREST

The Esselen Award for Chemistry in the public interest is one of the most prestigious honors provided by the Northeastern Section of the American Chemical Society. The award annually recognizes a chemist whose scientific and technical work has contributed to the public well-being, and has thereby communicated positive values of the chemical profession. The Awardee should be a living resident of the United States or Canada at the time of nomination, and the significance of this work should have become apparent within the five years preceding nomination.

The Esselen Award has no limitations with respect to the chemical field in which the nominees are active. Since its inception, the award has been given to the following chemists (see over for subjects):

1987: F. Sherwood Rowland 1997: Rangaswamy Srinivasan Mario J. Molina 1998: Kyriacos C. Nicolaou 1988: Alfred P. Wolf Joanna S. Fowler 1999: Robert S. Langer

1989: Carl Djerassi 2000: William A. Pryor

1990: Thomas J. Dougherty 2001: Joseph M. DeSimone

1991: Jerrold Meinwald 2002: Ronald Breslow Thomas Eisner 2003: Bruce D. Roth 1992: Bruce N. Ames 2004: James W. Jorgenson 1993: James G. Anderson 2005: Jean M. J. Fréchet 1994: Kary B. Mullis 2006: Richard D. DiMarchi 1995: Howard J. Schaeffer 2007: Michael A. Marletta 1996: Roy G. Gordon

THE AWARD CONSISTS OF A MEDAL AND A CHECK FOR $5,000. Travel expenses incidental to the conferring of this award will be reimbursed. The award will usually be held in Cambridge, Massachusetts at the April meeting of the Northeastern Section. The Awardee will deliver an address on the subject of the work for which the honor is being conferred, or for work in progress which is also directed to chemistry in the public interest.

TO NOMINATE a candidate please provide statements from two co-sponsors as well as a brief biography of the candidate, a description of the work which has been recognized as communicating the positive values of the chemistry profession, and copies of selected, pertinent articles. Popular news and feature articles should be included as an indication of public interest. Nominations and inquiries should be directed to Mr. Joseph A. Lima, c/o Karen Piper, 19 Mill Road, Harvard, MA 01451. NOMINATIONS SHOULD BE POSTED NO LATER THAN OCTOBER 15, 2007. Joint nominations are acceptable. The Committee will review the nominations and the award recipient will be notified by the first of February. PAST-AWARDEES AND TITLES OF AWARD ADDRESSES

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1987: F. Sherwood Rowland, University of California at Irvine, and Mario J. Molina, now at the Massachusetts Institute of Technology. Discovery of the Influence of Chlorofluorocarbons on the Ozone Layer.

1988: Alfred P. Wolf and Joanna S. Fowler, Brookhaven National Laboratories, Chemical

Procedures to Make Positron Emission Tomography a Practical Method in Medical Diagnosis.

1989: Carl Djerassi, Stanford University. Synthesis and Promotion of the First and Most

Common Birth Control Hormone.

1990: Thomas J. Dougherty, Roswell Park Cancer Institute. The Development of Photodynamic

Therapy for the Treatment of Malignant Disease

1991: Jerrold Meinwald and Thomas Eisner, Cornell University. Chemical Responses in the

Insect and Plant World.

1992: Bruce N. Ames, University of California at Berkeley. Methods for Detection of

Carcinogens and Causes of Aging and Cancer.

1993: James G. Anderson, Harvard University. Experimental Methods for Measuring Global

Ozone Loss.

1994: Kary B. Mullis. The Discovery of Polymerase Chain Reactions (PCR) for the

Replication of DNA Molecules.

1995: Howard J. Schaeffer, Burroughs Wellcome Company. Nucleosides with Antiviral

Activity - The Discovery of Acyclovir (Zovirax®).

1996: Roy G. Gordon, Harvard University, Low Emissivity Glass; Energy Conserving

Windows.

1997: Rangaswamy Srinivasan, UVTech Associates, The Widely Used Laser Methodology of

Tiny Focused Ablative Photodecomposition.

1998: Kyriacos C. Nicolaou, Scripps Research Institute, Chemical Synthesis and Chemical

Biology of Natural Substances

1999: Robert S. Langer, Massachusetts Institute of Technology, The Development of Unique

Polymers for Medical Applications.

2000: William A. Pryor, Louisiana State University, Vitamin E and the Prevention of Heart

Disease.

2001: Joseph M. DeSimone, University of North Carolina and North Carolina State University,

Green Chemistry for Sustainable Economic Development.

2002: Ronald Breslow, Columbia University, Chemistry Lessons from Biology and vice versa.

2003: Bruce D. Roth, Pfizer Global Research & Development, The Discovery and

Development of Lipitor® (Atorvastatin Calcium).

2004: James W. Jorgenson, University of North Carolina, The Magic of Capillaries in Chemical Separations and Analysis

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. 2005: Jean M. J. Fréchet, University of California at Berkeley, Functional Macromolecules: From Design and Synthesis to Applications.

. 2006: Richard D. DiMarchi, University of Indiana, Chemical Biotechnology as a Means to Optimal Protein Therapeutics

2007: Michael A. Marletta, University of California, Berkeley, Nitric Oxide in Biology: From Discovery to Therapeutics.

.

NESACS Fund-Raising Committee Annual Report Dorothy J. Phillips, Chair

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2008 Northeastern Section of ACS (NESACS) Fund-Raising Activities

Summary fund-raised through contributions: $38,425(details in Table 1)

1. Fourth Annual Golf-Tournament was held June 25, 2008. Funds came from the contributions made by companies as sponsors of holes. Each golfer paid a fee to play. Announcement published in May 2008 edition of Nucleus shown below. Primary organizers: Amy Tapper and Harry Mandeville 2. NESACS Vendor Fair was held during the second Advances in Chemical Sciences Symposium, April 11, 2008 at the Royal Sonesta Hotel in Cambridge, MA. “The symposium was a day-long celebration of Chemistry. Under the auspices of this conference, eminent scientists from the triad of government and industry and academia delivered plenary lectures. The conference brought together 300+ scientists for a scholarly event focusing on medicinal chemistry, organic synthesis and methodology. The symposium was co- sponsored by the US (East Coast) Section of the RSC, and IUPAC. Fundraising netted over $40,000. We thus continue to build a nucleus for the future: there is a lot of enthusiasm for having this as an annual event.” Excerpt from report by M. Chorghade, primary organizer.

3. Corporate solicitation was made from current contributors) and new scientific companies in geographical proximity to the Section. The list of corporate contributors from December 2008 Nucleus is attached. 4. NESACS YCC raised funds to support the German Exchange program and other events. 5. Creagen BioSciences made a $600.00 contribution to NESACS National Chemistry week program. 6. Additional $1000 was received from family estate of Wally Gleekman

Dorothy J. Phillips, Chair, Fundraising Committee, thanks all organizers of the above activities.

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Table 1 nd 2 Advances in Chemical Sciences Symposium Contributions $23,000.00 Income for Program Fees $11,325.00 Expenses $26,692.51 Corporate Gifts General $300.00 National Chemistry Week Creagen BioSciences $600.00 Medicinal Chemistry $1500.00 Medicilon Inc $400.00 Paptech Corp $400.00 SAPA-NE $700.00 YCC Events Strem Chemicals $500.00 Vertex Pharmaceutical 1000.00 Broad Institute 1100.00

Golf Fundraiser Golf Corporate Sponsors $9425.00 Lyophilization of NE (LSNE) $2000.00 Osmium SAFC Pharma $500.00 Oxygen PCI Synthesis $1300.00 Tritium Cambridge Major Labs $500.00 Oxygen Vertex Pharma $500.00 Oxygen Irix Pharmaceuticals $1, 500.00 Tritium Shasun $1,500.00 Tritium Aptuit $1,000.00 Tritium Others $625.00 Income from fees $8280.00 Expenses $9046.00

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Corporate contributors as listed in the Nucleus, December, 2008 Vol. LXXXVII, No. 4

Corporate Patrons ($2,000+) Abbott Bioresearch Genzyme Lyophilization Service of New England Merck National ACS Novartis 116

Pfizer Schering Corporation Sepracor Serono Reproductive Institute Vertex Pharmaceuticals Wyeth Pharmaceuticals

Patrons ($1,000 - $1,999) Aptuit Astra Zeneca R&D Boston Broad Institute Creagen Biosciences Estate of Wallace Gleekman IRIX Pharmaceuticals Millennium Pharmaceuticals PCI Synthesis Shasun USA Sirtris Pharmaceuticals Strem Chemicals, Inc. ZINK Imaging Ziopharm Oncology, Inc.

Donors ($300 - $999) Cambridge Major Laboratories Medicilon, Inc. Occidental Organix Peptech Corp. Royal Society of Chemistry SAFC Pharma SAPA-NE

REPORT OF THE GOVERNMENT RELATIONS COMMITTEE - 2008 Doris I. Lewis, Chair

Members: Tim Rose, Michael Strem, Doris Lewis, Liming Shao, Christopher Moreton, Michael Singer, Mukund Chorghade, Don Rickter, Decio Coutinho

Our Section has four active participants in the ACS Joint Board-Council Committee on Chemistry and Public Affairs, Ray Forsland, Timothy L. Rose, Peter Jacobi and Doris Lewis. All are members of the Legislative Action Network which send letters to Congress in support of

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ACS positions, as are many other members of the Northeastern Section. Additionally, Mike Strem has been active in contacting his congressman, Rep. Tierney.

NESACS Councilor Don Rickter Committee member Tim Rose and have been active in following The Safer Alternatives Bill (An Act for a Healthy Massachusetts: Safer Alternatives to Toxic Chemicals). Led by Senator Steven Tolman (D-Brighton) and Senator Pam Resor (D- Acton), efforts to move the bill forward in the Senate gained momentum in the wake of last year's product recalls over hazardous ingredients such as lead in children's toys and lipstick. It is supported by the Alliance for a Healthy Tomorrow (AHT), a coalition of over 160 organizations -health, labor, scientific, environmental, faith and community groups - working to promote the use of safer alternatives to toxic chemicals where feasible. ACS does not have an official position on the bill, but Dr. Rickter has kept in close touch with Bob Ross, Chief Policy Advisor for the Senate President and is scheduling a January 2009 meeting with Rep. Jay Kaufman.

Respectfully submitted, Doris Lewis

REPORT OF THE LOCAL ARRANGEMENTS COMMITTEE – 2008 Mary Burgess, Chair

The duty of this committee is to help arrange and coordinate the social part of the meeting. Our meetings were held at different locations in the area. Our role is to set up and greet our attendees at different dinner meeting locations. Various members of the section greet and check each person who is attending the evening meeting. Fees are considered according to the following: member, non-member, retired, or student to encourage more participation. Nine meetings were held during the year: January10,

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February14, March13, April 17, May 8, September 11, October 15, November13, and December 10. The following is data for the meetings held during 2008:

Date Location No. Program / Speaker Notes

1/10 UMass Boston 34 Dr. Hannah Sevian UMass Boston

2/14 Simmons College 29 Dr. Joyce P. Foster (Williams College) Joint Meeting and with NOBCChE Dr. Valerie P. Wilson (Brown University)

3/13 Harvard Faculty Club 85 Prof. Robert G. Bergman Richards Medal Univ. of California at Berkeley

4/17 Harvard Faculty Club 69 Dr. John A. Katzenellenbogen Esselen Award Univ. of Illinois at Urbana-Champaign

5/8 Northeastern University 75 Prof. Angela Belcher Education Night M. I. T.

9/11 Holiday Inn / Woburn 40 Symposium: New Developments Joint with MCG In Anti-Infective Research

10/15 Henderson House, 49 Dr. Peter Meltzer Hill Award / Weston Organix, Inc., Woburn 50-Yr Members

11/13 Brandeis Faculty Club 98 Prof. David K. Gosser Norris Award City College of New York and Prof. Jack A. Kampmeier Heyn Award University of Rochester Prof. Pratibha Varma-Nelson Indiana U.-Purdue U.

12/10 Holiday Inn / Woburn 57 Symposium: New Technologies Joint with MCG for Drug Discovery

Note: The numbers shown in column three represent the number of people who registered to attend the dinner. Additional people were present to hear the speakers but are not included in these counts.

2008 Annual Report from Medicinal Chemistry Group Dr. Raj (SB) Rajur, Program Chair for Medicinal Chemistry Division, NESACS.

The medicinal chemistry division of NESACS conducted three excellent symposia during the year 2008. The first symposium was held on May 14, 2008 at Holiday Inn Hotel in Woburn MA. The symposium topic was Cost, Speed, and Quality  Emerging Opportunities for Drug Discovery in Asia. Traditionally

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medicinal chemistry meetings focus on specific therapeutic areas. However, the main focus of this meeting was to bring the top level executives from prominent contract and collaborative research organizations from Asia to share their expertise and experiences in the drug discovery outsourcing arena. This was all day meeting attended by more than 200 people from local biotech/pharmaceutical companies and many students from academic centers. Chemistry and medicinal chemistry outsourcing, ADME outsourcing and Biology, DMPK, API outsourcing were the three main sessions. Several case studies were part of each session. Panel discussion was also part of the meeting, which was conducted by Dr. Kerry Spear of Sepracor Corporation, Marlborough, MA. The meeting was started by a welcome speech from the co-chair Dr. Liming Shao and keynote presentation was given by Dr. Bradley Miller, Director of Office of International Activities, American Chemical Society Washington DC. Dr. Norton Peet gave the opening remarks. Dr. Raj (SB) Rajur from CreaGen Biosciences, Dr. Steve Tam from Wyeth Pharmaceuticals, Dr. Dingwei Yu from AstraZeneca R&D and Dr. Kerry Spear from Sepracor Corporation chaired the sessions. The meeting was concluded with tasty dinner sponsored by SAPEA New England Chapter. The second symposium was held on September 21, 2008 at the Merkert Chemistry Center of Boston College Chestnut Hill, MA. The meeting was well attended by more than100 participants who enjoyed cutting edge research results presented by four well-known speakers from the pharmaceutical industry. Dr. John Williams, Senior Research Investigator at Microbiotix Corporation, Worcester, MA spoke on Nucleosides and the Challenge of Antivirals: ZSM-I-62 as a Candidate Anti-HCMV drug. Dr. Gregory S. Bisacchi, Associate Director at AstraZeneca R&D Boston spoke on Antibacterial Discovery: Past, Present, and Future. Dr. Roger Frechette, VP of Chemistry and R&D Operations at MaxThera, Inc, Beverly, MA spoke on the development of new antibiotics. The social hour, networking and dinner were part of the program. The keynote speaker for the evening was Dr. Milind Deshpande, Executive Vice President and Chief Scientific officer at Achillion Pharmaceuticals, New Haven, CT. Dr Deshpande spoke on the Discovery of Potent Antibacterial Agents for Treatment of Highly Drug-Resistant Pathogens. The symposium was well attended and there were more than 80 participants

The third and the annual symposium for the year 2008, was held on December 10, 2008 at Holiday Inn Hotel in Woburn MA. This symposium was a great success. There were more than 100 participants who enjoyed the topic New Technologies for Drug Discovery. Dr. John A. Porco, Jr., Professor and Director of Boston University Chemical Methodology and Library Development Center at the Boston University, Boston, MA spoke on New Approaches for Discovery of Chemical Reactions and Chemotypes. Dr. Scott L. Harbeson, Vice President of Research at Concert Pharmaceuticals, Inc. Lexington, MA spoke on Selective Deuterium Chemistry in Drug Discovery: Improved New Chemical Entities from Clinically Validated Therapeutics. The keynote speaker for the evening was Dr. Christopher G. Newton, Senior Vice President, at BioFocus DPI, Chesterford Research Park, Saffron Walden, Essex, UK. Dr Newton Spoke on Drug Discovery in the 21st Century - the Collaborative Paradigm”.

Dr. Raj (SB) Rajur, Founder, Chairman and CEO of CreaGen Biosciences, Inc., a Woburn-based Drug Discovery Company, is the Program Chair for NESCS Medicinal Chemistry Division, and he welcomed the guests and participants. Dr. Norton Peet, an International Pharmaceutical Consultant and meeting co- chair, from North Andover, gave an introductory presentation and moderated the symposium.

The symposium was concluded with the token of respect to the speakers by the program Chair, Dr. Rajur

______NESACS Medicinal Chemistry Symposium

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Cost, Speed, and Quality  Emerging Opportunities for Drug Discovery in Asia Date: Wednesday, May 14th, 2008 Location: Holiday Inn, 15 Middlesex Canal Park Road, Woburn, MA

Program Opening 8:15 ~ 8:20am Dr. Liming Shao , Chair, Medicinal Chemistry Group, NESACS Chemistry & Medicinal Chemistry Outsourcing 8:20 ~ 9:50am Chair: Dr. Raj (SB) Rajur, Chairman & CEO CreaGen Biosciences, Inc. 1. Experience of drug discovery chemistry outsourcing in India Dr. Pooran Chand Executive Director of Medicinal Chemistry, Biocryst Pharmaceuticals. USA 2. Bring Value to Its Customers: a Chinese Startup CRO’s Approach Dr. Michael Song CEO, Beijing PharmaScience, Beijing China 3. The Next Wave of Outsourcing in Pharmaceutical Industry and How to Prepare for the Paradigm Shift Dr. Xiaodong Wang CEO & President, PharmaAdvance, China Break 9:50am ~ 10:00 am

Key Note Presentation 10:00 ~ 10:40am Dr. Ge Li CEO, Wuxi Pharma Thec Integrated Discovery Outsourcing (ADME)

10:50 ~ 12:20 pm Chair: Dr Steve Tam, Director of Chemistry, Wyeth 1. Advantages of integrated research within the evolvingIndian discovery service model Ashis K. Saha, Ph.D. VP of Research, Chembiotek Research Pvt. Ltd. Kolkata, India 2. Creating world-class capabilities for integrated drug discovery in China Mr. John Oyler CEO, Bioduro

3. TBD Dr. Bruno Tse, VP, Business Development, PepTech Corporation, Burlington, MA Lunch 12:30 ~ 1:30 pm

Biology & DMPK 1:40 ~ 3:10 pm Chair: Dr. Dingwei Yu, Director of Cancer Chemistry, AstraZeneca R&D Boston 1. Discovery Biologics: Outsourcing Principles and Considerations Dr. Vincent Ling VP, Dragonfly Sciences, Shanghai, China 2. Current status of integrated pharmaceutical services beyond chemistry services in China Dr. Chun-Lin Chen CEO, GLP MPI-Medicilon Research, Shanghai, China TBD Break 3:10 ~ 3:20 pm

Managing from Distance, Case Study

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3:20 ~ 4:50 pm Chair: Dr. Kerry Spear 1. The Role of China in Drug Discovery in the 21st Century: A View from the Starting Gate Dr. Kerry Spear Executive Director, Drug Discovery, Sepracor Inc. MA, US 2. Creating Value in Drug Discovery through Integrated Chemical Operations Dr. Roger Xie Associate Director, Sirtris Pharmaceuticals, US 3. Long distance marriage of disease biology and systems biology platform for discovery of novel therapeutics: A case study Dr. Uday Saxena CEO, Kareus Therapeuticcs, Georgia US and Dr. Suri Venkatachalam CEO, Connexios Life sciences, Bangalore, India

Panel Discussion 4:55~5:35 Moderator: Dr. Kerry Spear

Reservations should be made no later than 12:00 noon on Wednesday, May 7, 2008. Please contact Marilou Cashman at (800) 872-2054 or (508) 653-6329 or [email protected]. . The fees for the symposia are: Members, $50 (Industry), $28 (Academic); Non-members, $60 (Industry), $30 (Academic); Retirees, $15; Students, $10. Anyone who needs handicapped services/transportation, please call a few days in advance so that suitable arrangements can be made. THE PUBLIC IS INVITED

September Meeting

The 889th Meeting Northeastern Section of the American Chemical Society Northeastern Section of the American Chemical Society

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JOINT MEETING: NORTHEASTERN SECTION, ACS AND MEDICINAL CHEMISTRY GROUP

Symposium

New DevelopmentsThursday - inSeptember Anti-Infective 11th, 2008 Research Organized by the Medicinal Chemistry Section Boston College, 2609 Beacon Street, Chestnut Hill, MA. of the Northeastern Section, American Chemical Society

Afternoon Program: Merkert Chemistry Center, Room 127 3.00 pm Refreshments 3.15 pm Welcome Raj (SB) Rajur, Program Chair, CreaGen Biosciences, Inc. Woburn, MA 3.20 pm Introductory Remarks Norton Peet, International R&D consultant, North Andover, MA 3.30 pm Nucleosides and the Challenge of Antivirals: ZSM-I-62 as a Candidate Anti-HCMV drug. John Williams, Senior Research Investigator, Microbiotix, Worcester, MA

4:15 pm Antibacterial Discovery: Past, Present, and Future Gregory S. Bisacchi, Associate Director, AstraZeneca R&D Boston 5:00 pm TBD

5:45 pm Social Hour, Murray Function Room, Yawkey Athletics Center, 4th Floor 6:30 pm Dinner

Evening program: Merkert Chemistry Center, Room 127 7:45 pm Isothiazolopyridones and Isothiazoloquinolones: Discovery of Potent Antibacterial Agents for Treatment of Highly Drug-Resistant Pathogens Milind Deshpande, Executive Vice President and Chief Scientific Officer, Achillion Pharmaceuticals, New Haven, CT

Dinner reservations should be made no later than 12:00 noon on Thursday, September 4th, 2008. Please contact Marilou Cashman at [email protected] or call (800) 872-2054 or (508) 653-6329. Reservations not canceled at least 24 hours in advance must be paid. Anyone who needs handicapped services/transportation, please call a few days in advance so that suitable arrangements can be made. Reservations not canceled at least 24 hours in advance must be paid. Payment is made at the door by cash or check (no credit cards.) Members, $28.00; Non- members, $30.00; Retirees, $18.00; Students, $10.00.

John Williams Nucleosides and the Challenge of Antivirals: ZSM-I-62 as a Candidate Anti-HCMV drug.

Viral diseases provide particular challenges for the medicinal chemist. Because the viruses co-opt many cellular functions, it is difficult to selectively inhibit viral replication while maintaining normal cellular function. ZSM-I-62 represents a novel class of methylenecyclopropane nucleosides that is both highly active against several human herpesviruses, and is also quite non-cytotoxic. The development of ZSM-I-62 as an anti-Human Cytomegalovirus (HCMV) agent will be discussed ______Dr. Williams attended the University of Wisconsin-Parkside where he earned a BS in both Biology and Chemistry. Seeking a discipline in which he could integrate both fields, he entered the Medicinal Chemistry program at the

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University of Michigan under the instruction of Dr. Leroy Townsend and Dr. John Drach, and studied nucleoside antivirals. Upon completing his Ph.D. in 2003, he joined the group of Dr. F. Ivy Carroll at the Research Triangle Institute (RTI), where he contributed to a program investigating drugs of abuse. He then joined Microbiotix in 2005, where he continues working on several antibacterial and antiviral programs. ______

Gregory S. Bisacchi “Antibacterial Discovery: Past, Present, and Future”

This talk will cover 1) a brief summary of historical antibacterial agents; 2) discussion, as case studies, of several antibacterial Discovery approaches currently being pursued at AstraZeneca, and 3) a personal reflection on what new or different Discovery approaches might be needed in the future to supply the antibacterial pipeline, especially for gram-negative antibacterial agents. ______Greg Bisacchi is Associate Director, Infection Chemistry at AstraZeneca. Greg started his medicinal chemistry career at Squibb in New Jersey, first in natural product based anti-infectives (including monobactams). Later, at Bristol-Myers Squibb, he worked in the areas of antivirals, antidiabetics, and pulmonary and cardiovascular agents. Greg received his BS and PhD in chemistry at UCLA and did a postdoc at Stanford University. ______

Milind Deshpande Isothiazolopyridones and Isothiazoloquinolones: Discovery of Potent Antibacterial Agents for Treatment of Highly Drug-Resistant Pathogens

There is a growing unmet medical need for effective treatments of drug resistant bacteria. Ideally, newer drugs will not only cure infections caused by drug-resistant pathogens, but will also prevent emergence of drug resistance. Isothiazolopyridones and isothiazoloquinolones were designed as inhibitors of bacterial enzymes essential for DNA replication. These new classes of anti-bacterial agents display excellent broad spectrum activity. In vitro emergence of resistance to these new antibiotics is also significantly reduced. Microbiology and Chemistry of Isothiazolopyridones and isothiazoquinolones will be presented ______

Milind Deshpande joined Achillion in September 2001 as Vice President of Chemistry, was named Head of Drug Discovery in April 2002, Senior Vice President of Drug Discovery in December 2002, Senior Vice President and Chief Scientific Officer in December 2004, and Executive Vice President of Research and Chief Scientific Officer in June 2007.

Prior to joining Achillion, Dr. Deshpande was Associate Director of Lead Discovery and Early Discovery Chemistry at the Pharmaceutical Research Institute at Bristol-Myers Squibb from 1991 to 2001, where he managed the identification of new clinical candidates to treat infectious and neurological diseases. From 1988 to 1991, he held a faculty position at Boston University Medical School. Dr. Deshpande received his Ph.D. in Organic Chemistry from Ohio University, following his undergraduate education in India.

December Meeting Northeastern Section The 892nd Meeting of the American Chemical Society Northeastern Section of the American Chemical Society

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JOINT MEETING: NORTHEASTERN SECTION, ACS AND MEDICINAL CHEMISTRY GROUP

Symposium

New Technologies for Drug Discovery Organized by the Medicinal Chemistry Group of the Northeastern Section, American Chemical Society

Wednesday - December 10th, 2008 Holiday Inn, 15 Middlesex Canal Park Road, Woburn, MA

3.00 pm Refreshments 3.15 pm Welcome Raj (SB) Rajur, Program Chair, CreaGen Biosciences, Inc. Woburn, MA 3.20 pm Introductory Remarks Norton Peet, International R&D Consultant, North Andover, MA 3.30 pm New Drugs for Stroke: What to Do? Klaus van Leyen, Assistant Professor, Harvard Medical school, Charlestown, MA 4:15 pm New Approaches for Discovery of Chemical Reactions and Chemotypes John A. Porco, Jr., Professor and Director, Boston University Chemical Methodology and LibraryDevelopment Center, Boston, MA 5:00 pm Selective Deuterium Chemistry in Drug Discovery: Improved New Chemical Entities from Clinically Validated Therapeutics Scott L. Harbeson, Vice President, Research, Concert Pharmaceuticals, Inc., Lexington 5:45 pm Social Hour 6:30 pm Dinner 7:45 pm Drug Discovery in the 21st Century -- The Collaborative Paradigm Christopher G. Newton, Senior Vice President, BioFocus DPI, Chesterford Research Park, Saffron Walden, Essex, CB10, IXL, UK

Dinner reservations should be made no later than 12:00 noon on Wednesday, December 3, 2008. Please contact Marilou Cashman at [email protected] or by phone at (800) 872-2054 or (508) 653- 6329. Reservations not canceled at least 24 hours in advance must be paid. Anyone who needs handicapped services/transportation, please call a few days in advance so that suitable arrangements can be made. Payment is made at the door by cash or check (no credit cards.) Members, $28.00; Non- members, $30.00; Retirees, $18.00; Students, $10.00.

THE PUBLIC IS INVITED

From the Nucleus - sample announcement

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Membership Committee Michaeline Chen, Chair

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2008 NESACS Annual Report

Membership Committee – Michaeline Chen, Chair

A total of 908 “Welcome New Member” letters were sent during 2008. Month Date New Transferred Totals Members Members January 4 36 32 68 February 16 33 38 71 March 28 42 22 64 April 21 21 70 91 May 31 30 27 57 June 23 34 79 113 July 18 34 16 50

August 24 98 122 220 The number of “welcome new member” letters of May, June, July were all sent on 24 Aug. 2008 for September monthly meeting. September 23 98 76 174 October November 19 76 80 156 December 29 28 27 55 Total 437 470 907

According to Karen Piper, our business manager of the Nucleus, from whom I receive the new members list each month, the Northeastern Section of ACS count of members is currently at 6958 (March 2008).

There were about 50 new members who attended our Local Section Dinner Meetings during 2009 The purpose of the membership committee is to welcome new members, assist and support our members in need and refer them to the appropriate resources; monitor membership in our section and recommend chemists and chemical scientists for membership. I have always provided Membership Applications to non-members who attended our Monthly Dinner Meetings.

More new members are interested in employment opportunities and job information. Some are interested in the National Chemistry Week, others are interested in Government Relations, Hospitality and other functions. New members are integrated by assigning them specific functions. We try to assist and support our new members and refer them to the appropriate resources.

The committee works very closely with Mrs. Karen Piper, Business Manager of The Nucleus. She supplies the labels for the new members’ roster. Our Editor of The Nucleus, Dr. Michael Filosa, places a short note in the monthly issues of The Nucleus to invite New Members to our monthly meeting and dinner. Our section secretary, Marilou Cashman, in charge the reservations of the monthly dinner meetings. Mary Burgess, our Hospitality Chair.

A copy of my “welcome letter” to new members is attached.

February 16, 2008

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Dear Colleague

Congratulations on joining the American Chemical Society and its Northeastern Section. Welcome aboard! We intend to make sure your decision to join was a wise one. We also provide you with a broad range of services and opportunities to help you personally and professionally.

I would like to invite you to be a guest of our section at one of our monthly dinner-lecture meetings of your choice. Our dinner-lecture meetings are usually held on the second Thursday of each month (September through May). Social hour is at 5:30pm, dinner is at 6:30pm., with a guest speaker to follow. The lectures are on a drop-in basis; reservations are necessary for dinner.

Our next monthly dinner meeting is for the Richards Medal, The medal is awarded every two years for conspicuous achievement in chemistry on March 13, 2008 at Harvard Faculty Club, 21 Quincy St., Cambridge, MA. 5:30 pm - Social hour; 6:15pm - Dinner.

At 8:15 pm, Richard Medal Award ceremony is at Mallinckrodt Building, Pfizer Lecture Hall - MB 23, 12 Oxford St., Cambridge, MA. This year the Richard Medal recipient is Professor Robert G. Bergman of the University of California at Berkeley. Topic: “Selective Organic and Organometallic Transformations Mediated by Molecular and Supramolecular Environments.”

For dinner reservations, please contact our section secretary, Marilou Cashman at 1-800-872-2054 or 1-508-653-6329, or E-mail: [email protected], on or before Thursday, March 6th, a week before the Dinner Meeting and let her know that you are a new member. We welcome your participation and look forward to meeting you.

Information about our monthly meetings will be provided through the Nucleus, our monthly publication. Have you received a copy of the Nucleus? If not, please contact the Business Manager of the Nucleus, Karen Piper at 1-978-456-8622 or E-mail: [email protected] Once again, welcome to ACS and the Northeastern Section!

Sincerely yours,

Michaeline F. Chen - Chair, Membership Committee Northeastern Section, ACS E-mail: [email protected] & [email protected] Tel: 781-235-5201

National Chemistry Week Report - 2008

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Christine Jaworek-Lopes, Chair

In preparation for National Chemistry Week 2008, a volunteer preparation day was held at Emmanuel College on Saturday, October 4, 2008. More than 30 individuals attended this event, which allowed volunteers to practice the hands-on activities and demonstrations in advance of the October celebration. Staff members from the Museum of Science-Boston and the Boston Children’s Museum staff were on hand to choose which activities worked best for their respective venues.

On Saturday, October 18, 2008, the Northeastern Section of the American Chemical Society sponsored a National Chemistry Week 2008 Kick-Off Event at Museum of Science-Boston (MoS). More than 45 volunteers (from ACS, the Brauner Committee, Emmanuel College, Malden High School, Stonehill College, Suffolk University, Tufts University) ensured that the more than 450 visitors to the daylong event enjoyed a number of hands-on activities.

Hands-on activities and demonstrations that were performed throughout the week included: determining the starch content in foods, learning about the sugar content of a variety of foods, UV beads and sunscreen, make your own bouncing balls, make your own Gatorade, learning about electrolytes, water resistant materials, chemistry of hot and cold packs.

Among the highlights of the day were the two Phyllis A. Brauner Memorial lectures, presented by Dr. Bassam Shakhashiri, Professor of Chemistry at the University of Wisconsin-Madison. These captivating lectures were enjoyed by children and adults alike. Approximately 400 individuals attended these lectures. The 1 pm lecture was free with admission to the Museum. Individuals wishing to attend the 4 pm lecture only could do so without purchasing a ticket to enter the Museum.

Our section also participated in the survey program piloted by the ACS Committee of Community Activities.

Five hundred and ninety three students attended the High School Science Series event at the MoS-Boston on October 24, 2008. The students were from: Abington High School (HS), Advocates for Home Education in MA, AOK (Home schoolers in Cambridge), Arlington HS, Codman Academy Charter Public School, East Boston High School, Boston Day and Even Academy, John D O’Bryant School, Greater Lowell Technical HS, Malden HS, Old Rochester Regional HS, Parkway Academy of Technology and Health, St. Joseph High School Open Bible Academy. These students participated in a number of hands-on activities and demonstrations related to the yearly theme. In addition, the students attended a lecture-demonstration given by David Sittenfeld, MoS-Boston, and Patrick Drane, Lowell Baseball Institute regarding materials used in sports. Admission for all students was covered by a generous donation from Creagen Biosciences, Inc. and the MoS-Boston.

The students also had the opportunity to participate in the High School Series Optional Chemistry Problems. The questions were based on two of the activities in which the students participated. Twelve students chose to solve one or both questions. Two winners were randomly chosen and the winner received a $25.00 gift certificate to www.amazon.com and a National Chemistry Week t-shirt. The teacher of the winning students received a $25.00 gift certificate to www.teachersource.com.

In addition, an NCW event was held at the Boston Children’s Museum on Saturday, October 25, 2008. Approximately 500 individuals participated in NCW hands-on activities and demonstrations. A particular favorite at the Boston Children’s Museum was making bouncing balls. More than 30 volunteers from Creagen Biosciences, Inc.; Emmanuel College, Gordon College, Merck Research Laboratories- Boston, Pingree School, Suffolk University, and Tufts University were available to assist visitors throughout the day.

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Children grades K-12 were able to participate in the national poster competition. Two posters were received. The winning poster from the NESACS was submitted by Jordan Sheehan from Bishop Guertin High School. Children grades K-12 had the option of participating in two puzzle contests. The puzzles were designed by Dr. Christopher Morse. Eleven students completed the Sudoku puzzle and 14 students completed the sport word quiz.

Finally, the section held a sneaker recycling event. A local daycare, elementary school, and Emmanuel College all participated in this event. More than 100 pairs of sneakers will be brought to the Wrentham Outlets (an official Nike drop-off location).

NCW events were posted in the Nucleus (local section newsletter), as a flyer (at the Connections to Chemistry workshop), on websites (including www.nesacs.org), in the Wellesley Townsman, via email to my NCW teacher list, and on WBUR (Science Friday).

In addition to the donation from Creagen Biosciences Inc., Strem Chemicals also donated funds to defray the costs associated with NCW 2008 events.

Respectfully submitted,

Christine H. Jaworek-Lopes NCW Chair

REPORT OF THE NOMINATING COMMITTEE - 2008 Mukund Chorghade, Chair

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The Nominating Committee was chaired by Dr. Mukund Chorghade immediate Past-Chair of the Northeastern Section. The following are the results of the balloting for the 2009 ACS officers of the Northeastern Section. There were a total of 463 ballots counted..

NESACS ELECTION RESULTS - 2008 BALLOT

Name Votes Result Position Term

John McKew 215 Elected Chair-Elect 1 year Norton Peet 197

James Piper 401 Elected Treasurer 2 years

Anthony Rosner 400 Elected Auditor 2 years

Michael Strem 415 Elected Trustee 3 years

Doris Lewis 357 Elected Councilor 3 years Mary Burgess 332 Elected Councilor 3 years Morton Hoffman 332 Elected Councilor 3 years Michael Filosa 330 Elected Councilor 3 years Kathi Browne 330 Elected Councilor 3 years Christine Jaworek-Lopes 321 Elected Alternate Councilor 3 years. Patrick Gordon 316 Elected Alternate Councilor 3 years Lawrence Scott 312 Elected Alternate Councilor 3 years Donald Rickter 264 Elected Alternate Councilor 3 years Liming Shao 253 Elected Alternate Councilor 3 years

Myron Simon 305 Elected Director-at-Large 3 years Ralph Scannell 288 Elected Director-at-Large 3 years Mukund Chorghade 205

Amy Tapper 324 Elected Nominating Committee 1 year Dorothy Phillips 280 Elected Nominating Committee 1 year Jerry P. Jasinski 223

Kathi Browne 244 Elected Norris Award Comm. 4 years Jerry Jasinski 219 Elected Norris Award Comm. 4 years Ralph Scanell 193 Raj Rajur 155

NORRIS AWARD COMMITTEE ANNUAL REPORT 2008

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Barry B. Snider, Chair

2008 Annual Report to ACS on the work of the Norris Committee

Committee members for 2008

Professor Mort Hoffman, Boston University Professor Mary Jane Shultz, Tufts University Professor Donald Smith, University of Massachusetts Dartmouth Professor Barry Snider, Brandeis University, Chair Professor Jerry Mohrig, Carleton College Professor Mary Virginia Orna, College of New Rochelle Professor John W. Moore, University of Wisconsin, Editor, J. Chem. Ed.

Committee Charge The James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry is presented annually by the Northeastern Section to an educator who is both an excellent classroom teacher and whose professional activities have had a wide-ranging effect on chemical education. The award consists of an honorarium for $3000 and an award certificate.

Committee Activities A total of 8 nominations were considered including updated re-submissions of material received in previous years. Copies of the files were circulated to the committee. A conference call was held by the committee on June 3, 2008. At this virtual meeting the committee selected David Gosser, City College of New York, Professor Jack Kampmeier, Rochester University and Prof Pratibha Varma-Nelson, Indiana University-Purdue University for developing the peer-led team learning approach to the teaching of general and organic chemistry.

Preliminary notifications of the award were sent to The Nucleus and The Journal of Chemical Education, and appeared in their summer editions.

The annual award dinner, presentation, and lecture was held on November 13, 2008 at Brandeis University. Attendance was between 95 and 100. The lecture by the awardees Professors Gosser, Kampmeier, and Varma-Nelson on peer-led team learning was very well received and generated much discussion

Mort Hoffman takes over as chair of the Norris Award Committee on January 1, 2009.

Solicitations for nominations for the 2009 Award have been sent to the Nucleus and Journal of Chemical Education. The Norris Award Section of the NESACS Web Site was also updated to include the call for nominations and information on submission.

Respectfully submitted, Barry Snider, Chair

Call for Nominations

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James Flack Norris Award for Outstanding Achievement in These may show the impact of the nominee’s teaching in inspiring colleagues the Teaching of Chemistry and students toward an active Nominations are invited for the 2008 life in chemistry and/or related sciences, James Flack Norris Award for Outstanding or may attest to the influence of Achievement in the Teaching the nominee’s other activities in chemical of Chemistry. The Norris Award, one education, such as textbooks, journal of the oldest awards given by a Section articles, or other professional of the American Chemical Society, is activity at the local or national level. presented annually by the Northeastern The committee looks for impact of the Section. The Award consists of a certificate candidate’s activities at the National and an honorarium of $3,000. and International level. Nominees must have served with The nomination materials should special distinction as teachers of chemistry consist of a primary nomination letter, at any level: secondary school, supporting letters, the candidates curriculum college, and/or graduate school. Since vitae. Reprints or other publications 1951, awardees have included eminent should NOT be included. Ther and less widely-known but equally material should not exceed thrity effective teachers at all levels. pages. The awardee for 2007 was Professor Please direct questions about the Diane M. Bunce of the Department content of a nomination to the of Chemistry of the Catholic University Chairperson of America of the Norris Award Committee. Nominations should focus on the For 2008 the Committee Chairperson candidate’s contributions to and effectiveness is Professor Barry Snider, in teaching chemistry. The Department of Chemistry, Brandeis nominee’s curriculum vitae should be University. email: included. Seconding letters are also an snider(at)Brandeis.edu . important part of a nominating packet. Send nomination packets electronically in Adobe PDF format to Ms. Marilou Cashman, Administrative Secretary of NESACS. email: mcash0953(at)aol.com. The deadline for nominations is April 15, 2008. _

PROGRAM

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Brandeis Faculty Club Brandeis University Waltham, MA

5:30 P.M. Social Hour 6:15 P.M. Dinner 7:45 P.M. Award Ceremonies

Marietta Schwartz Chair, Northeastern Section, presiding

Presentation of Arno Heyn Memorial Book Award to Vivian Walworth by Mary Mahaney Chair, Board of Publications

James Flack Norris Myron S. Simon Archivist, Northeastern Section, ACS

Introduction of Norris Award Recipient Morton Z. Hoffman Professor Emeritus, Boston University and 2005 Norris Award Recipient

Presentation of Norris Award Barry B. Snider Chair, Norris Award Committee

Norris Award Address “Peer-led Team Learning”

David K. Gosser, Jr. City College of New York Jack A. Kampmeier University of Rochester Pratibha Varma-Nelson Indiana University-Purdue University

PRIOR RECIPIENTS OF THE JAMES FLACK NORRIS AWARD

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FOR OUTSTANDING ACHIEVEMENT IN THE TEACHING OF CHEMISTRY

George Shannon Forbes ...... 1951 John Xan ...... 1953 Harry Nicholls Holmes ...... 1955 Norris Watson Rakestraw ...... 1956 Emma Perry Carr-Mary Lura Sherrill ...... Spring, 1957 Farrington Daniels ...... Fall, 1957 Herman Irving Schlesinger ...... Spring, 1959 Louis Frederick Fieser ...... Fall, 1959 Louis Plack Hammett ...... 1960 Joel Henry Hildebrand...... 1961 Ralph Lloyd Shriner...... 1962 Avery Allen Ashdown...... 1963 James Arthur Campbell - Lawrence Edward Strong ...... 1964 Walter John Moore...... 1965 John Arrend Timm - Edgar Bright Wilson ...... 1966 Edward Lauth Haenisch ...... 1967 Samuel Edward Kamerling - William Campbell Root ...... 1968 Joseph Edward Mayer ...... 1969 Hubert Newcombe Alyea ...... 1970 Charles Lester Bickel ...... 1971 Saul Gerald Cohen ...... 1972 Eugene George Rochow...... 1973 Grant Hopkins Harnest...... 1974 Leonard Kollender Nash...... 1975 Malcolm Mackenzie Renfrew...... 1976 Anna Jane Harrison...... 1977 Paul Doughty Bartlett - Henry C. McBay...... 1978 Harry Hall Sisler...... 1979 Robert C. Brasted...... 1980 Fred Basolo...... 1981 William Thomas Lippincott...... 1982 Bassam Z. Shakhashiri ...... 1983 Henry A. Bent...... 1984 Derek A. Davenport ...... 1985 Glenn A. Crosby ...... 1986 Joseph B. Lambert ...... 1987

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Dana W. Mayo - Ronald M. Pike...... 1988 Jerry R. Mohrig...... 1989 Joseph A. Schwarcz ...... 1990 John W. Moore ...... 1991 Jerry A. Bell...... 1992 Arthur C. Breyer ...... 1993 Samuel P. Massie...... 1994 Michael P. Doyle ...... 1995 Mary Virginia Orna...... 1996 A. Truman Schwartz ...... 1997 Angelica M. Stacy...... 1998 Joseph J. Lagowski ...... 1999 Billy Joe Evans ...... 2000 Dennis G. Peters ...... 2001 Zafra Lerman...... 2002 David N. Harpp...... 2003 Richard N. Zare ...... 2004 Morton Z. Hoffman...... 2005 Brian P. Coppola...... 2006 Diane M. Bunce...... 2007

JAMES FLACK NORRIS: THE MAN AND THE AWARD*

The James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry pays tribute to outstanding contributions to the field of chemical education and in so doing honors the memory of a distinguished teacher of chemistry: James Flack Norris.

The Award The Norris Award is one of the oldest national awards of the American Chemical Society and is presented annually by the Northeastern Section. The recipient is selected from an international list of nominees who have served with special distinction as teachers of chemistry at any level and whose efforts have had a wide-ranging effect on chemical education. The award has been given for a wide variety of achievements: for outstandingly effective textbooks, lecture demonstrations, or laboratory experiments, for editing the Journal of Chemical Education, for developing the Chemical Educational Material Study Project, or for new ways to teach laboratory courses in chemistry. Always, and this is of the utmost importance, the specific achievement must be coupled with dedicated teaching of chemistry at the graduate, undergraduate, or high school level. The award consists of a citation and an honorarium.

The Man James Norris was born in 1871 in Baltimore. He was the fifth of nine children and attended schools in that city and in Washington, D.C. His collegiate career started at Johns Hopkins University, from which he graduated with an A.B. degree, Phi Beta Kappa, in 1892. He was strongly attracted by the great Ira Remsen and consequently decided to carry out his graduate studies at Johns Hopkins where he investigated complex compounds of selenium and tellurium. In 1895 he obtained his Ph.D. After graduation, Professor Norris served in the Chemistry Department of M.I.T. In 1904 he then moved to the newly founded Simmons College to become its first Professor of Chemistry and to head its School of Science. He remained at Simmons until 1915 except for 1910-11 when,

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feeling the need for more physical chemistry, he spent a sabbatical with Fritz Haber at Karlsruhe. After one year at Vanderbilt University, Norris returned to M.I.T. where he remained for the next 24 years as an enthusiastic and successful teacher of chemistry. On February 4, 1902 he was married in Washington, D.C. to Anne Bent Chamberlin, daughter of an Army Captain. They had no children. Professor Norris died in Cambridge, Massachusetts on August 4, 1940.

In 1916 Norris was a member of the Naval Consulting Board and during World War I he served as a Lt. Colonel in the Chemical Warfare Service. After the war, he served for ten years as vice chairman and chairman of the Division of Chemistry and Chemical Technology of the National Research Council.

Although serious when the occasion called for it, the debonair Norris was known as "Sunny Jim" to a host of friends who found him a jovial companion.

His activities in the ACS were many: Chairman of the Northeastern Section in 1904 and President of the National Society in 1925 and 1926. As President of the Society, he did much to improve and clarify the finances of the society. He was also active in the National Research Council and in IUPAC, serving as vice president of the latter from 1925-28. He was an honorary member of the Rumanian Chemical Society and of the Royal Institute of Chemistry in Great Britain. In 1937, he received the gold medal of the American Institute of Chemists for "outstanding service as a teacher and as an investigator." Norris was one of the first chemists to study the structure- reactivity relationship of organic compounds on a systematic basis. Between 1912 and 1922 he authored four influential textbooks in inorganic and organic chemistry. The income from those texts, at least in part, formed the foundation of the bequest from Mrs. Norris to the Northeastern Section in 1948. The purpose of this bequest, to quote the will of Mrs. Norris, is "to keep green the memory of James Flack Norris."

The Norris Fund has grown over the years with judicious management by the Trustees of the Northeastern Section. From its income the Section sponsors two James Flack Norris Awards: the James Flack Norris Award in Physical Organic Chemistry, administered by the National ACS, and the James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry. Tonight's recipient joins a distinguished group of predecessors.

*Taken from the biographical memoir of James Flack Norris by John D. Roberts and from the biography of James Flack Norris given by Joseph Bornstein at the presentation of the James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry.

2008 Norris Award Winners

Jack A. Kampmeier, Pratibha Varma-Nelson, David K. Gosser, Jr.

NORTHEASTERN SECTION

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of the AMERICAN CHEMICAL SOCIETY

Presentation of the Fifty-seventh

JAMES FLACK NORRIS AWARD for Outstanding Achievement in the Teaching of Chemistry to PROFESSOR DAVID K. GOSSER, JR. PROFESSOR JACK A. KAMPMEIER PROFESSOR PRATIBHA VARMA-NELSON

Thursday, November thirteenth Two thousand eight

Brandeis Faculty Club Brandeis University Waltham, MA

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Sample Citation presented to Norris Award Winners - same citation presented to Jack A. Kampmeier and Pratibha Varma-Nelson

The Northeastern Section of the American Chemical Society confers the fifty-seventh

James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry

on David K. Gosser, Jr. Professor of Chemistry City University of New York (City College)

In recognition of a career exemplifying excellence in chemical education

You receive this award jointly with Jack A. Kampmeier, Professor of Chemistry Emeritus at the University of Rochester, and Pratibha Varma-Nelson, Professor of Chemistry at Indiana University-Purdue University Indianapolis, for your leadership role in developing the Peer-Led Team Learning (PLTL) Workshop model for teaching chemistry over the past fifteen years. PLTL introduces a new structure, the peer-led Workshop, where students work together to solve challenging problems designed by the faculty to engage them with the subject material and with each other providing an active learning experience for the students, a leadership role for the undergraduate peer leader and a creative new dimension to faculty teaching. Currently, 1500-2000 peer leaders are engaged on more than 150 college and university campuses to facilitate Workshops for more than 20,000 students per year.

Barry B. Snider November 13, 2008 Marietta Schwartz Chair, Norris Award Committee Chair, Northeastern Section

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From the Nucleus

Northeast Regional Meeting (NERM) Submitted by Morton Z. Hoffman

More than 600 chemists, including 225 undergraduate and graduate students, gathered on the west coast of New England for the 35th Northeast Regional ACS Meeting (NERM 2008) in Burlington, Vermont, on June 29-July 2, 2008; . Hosted by the Green

Mountain Local Section and cosponsored by the Chemical Institute of Canada, the meeting had “Chemistry Without Borders” as its theme. With many other industrial, academic, and international sponsors, including ten ACS divisions and the Royal Society of Chemistry, the meeting offered nearly 450 oral and poster presentations and an exhibition with 18 vendors and two non-profit groups. Among the attendees were Bruce Bursten (ACS President) and Anne O’Brien (ACS District I Director).

The meeting featured invited and contributing speakers across a wide range of topical symposia, including green chemistry, polymer chemistry, chemical biology, environmental chemistry, organic synthesis, layered materials, energy, industrial chemistry and innovation, inorganic chemistry, physical chemistry, analytical chemistry, medicinal chemistry, biochemistry, modeling and computer simulation, and chemical education. There were many workshops and programs for high school teachers, students, and chemistry enthusiasts. Tours to IBM’s Burlington Design Center and Ben & Jerry’s ice cream factory, and an evening of standup comedy with chemical engineering professor Peter Ludovice (Georgia Tech) and professional performer Rusty DeWees (“The Logger”) were part of the social program.

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The meeting ended with a conference cruise and award dinner aboard the Spirit of Ethan Allen III on Lake Champlain. The weather cooperated, producing a glorious early summer sunset. The following awards were presented:

The Green Mountain Local Section “Salute to Excellence” Award to Omya, Inc., for its contributions to chemistry and science education and outreach in the local community; o The ACS Division of Chemical Education Northeast Region Award for Excellence in High School Teaching to Steve Lantos (Brookline (MA) High School) for his creative, effective, and inspiring connections to his students; o The 2007 E. Ann Nalley Northeast Region Award for Volunteer Service to the ACS to Deborah Janes and Timothy Wilson (Eastman Kodak Company, Rochester, NY) for their involvement in science education outreach, and the 2008 Award to Christine Jaworek-Lopes (Emmanuel College, Boston, MA) for her untiring work as coordinator of National Chemistry Week activities for the Northeastern Local Section; o The Stanley C. Israel Regional Award for Advancing Diversity in the Chemical Sciences to Todd Pagan (National Technical Institute for the Deaf and the Rochester (NY) Institute of Technology) for his work in educating hearing-impaired students toward careers in the chemical sciences; o The ACS Regional Industrial Innovation Award to Dana Bookbinder, Ming-Jun Li, and Pushkar Tandon (Corning, Inc., Corning, NY) for their work in producing air-glass composite optical fibers; o The ACS Northeast Region Award for Achievements in the Chemical Sciences to Abraham Clearfield (Texas A&M University) for his work with layered phosphonates.

The Board of Directors of the Northeast Region of the ACS, Inc., held its annual meeting on July 2; it unanimously voted to commend Willem Leenstra (University of Vermont; Green Mountain Local Section), the General Chair of NERM 2008, for leading the organizing committee of this very successful NERM. The Board re-elected Christopher Masi (Westfield State College; Central Massachusetts Local Section) and Wayne Jones (SUNY Binghamton; Binghamton Local Section) to two-year terms (2009-10) as Secretary and Treasurer, respectively; continuing as Chair and Vice Chair of the Board are Julianne Smist (Springfield College; Connecticut Valley Local Section) and Richard Cobb (Eastman Kodak; Rochester Local Section), respectively.

The financial condition of the Northeast Region, Inc., is very good due to the financial success of the 2005 and 2006 Northeast Regional Meetings. Sinking fund loans of $4,000 each have been provided to NERM 2009 and NERM 2010; the loans will be paid back if the net financial outcomes of the meetings are positive.

NERM 2009 will be hosted by the Connecticut Valley Local Section on October 7-10 at the Hartford Hilton in Hartford, Connecticut, with Julianne Smist as the General Chair and Tyson Miller (University of Connecticut) and Edward Fitzgerald (Trinity College) as the Program Chairs; . Because the Middle Atlantic Regional Meeting (MARM) will not meet in 2009 and NERM will lead into the Columbus Day weekend and New England foliage displays, attendance of at least 500 (and most likely significantly more) is anticipated. Martin Walker (SUNY Potsdam; Northern New York Local Section) will serve as the General Chair for NERM 2010, June 2-5.

An expression of interest has been advanced by the Central Massachusetts Local Section to host NERM 2011 in the Worcester area; programmatic and logistical support could be made available through the Northeastern Local Section. Christopher Masi will investigate the possibility of

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organizing the meeting, and will make a decision prior to the ACS National Meeting in Salt Lake City in March 2009. The Rochester Local Section is preparing a bid to host NERM 2012.

The Northeast Region Board will meet next during NERM 2009, October 7-10, at the Hartford Hilton in Hartford, CT.

From the Nucleus

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REPORT OF THE PROFESSIONAL RELATIONS COMMITTEE - 2008 Submitted by Mukund S. Chorghade

The NESACS Professional Career Services Committee is dedicated to providing ACS Members with the best and latest tools to manage careers: we offer career guidance and focus on the components of targeting the job market, personal assessment, identifying market trends, credentials, research and networking. We have a comprehensive (lecture, demo and review) program that provides assistance in writing winning resumes and cover letters, learning various techniques and skills needed for a successful job interview and negotiating an attractive job offer.

Mukund Chorghade, Chair of this committee, attended both National Meetings and actively participated in the work of the ACS Department of Career Services and Professional Development in reviewing resumes and conducting mock interviews. Dr. Daniel Eustace has been a most welcome and effective contributor to these. Special accolades are due to him for helping in redesigning and participating in several innovative ACS presentations and personally leading highly and superbly interactive and novel workshops on interviewing, career development etc. There has been considerable audience participation from employers and interviewees. Both Dan Eustace and Mukund Chorghade have been selected to participate in the ACS National “Train the Trainer’s Program” and received additional training last year. We also participated in a special event at the University of Rhode Island

Dan Eustace also presented at the afternoon Career Services Employment Seminars that were held preceding the regular meeting of the Northeastern Section. We introduced this as a regular feature in all the monthly meetings (January-June). Typically, a lecture on resume presentations was presented and publications of the ACS National Employment Services were distributed. These publications were also distributed at each of the monthly meetings in the evening. Also, at the monthly meetings assistance with employment was available. Such assistance has been continued by telephone and e-mail, year around. This year as an innovative attempt to network employment-seekers with professional recruiters, we co- opted two highly respected industry professionals Megan Driscoll and Jennifer Sass, Pharmalogics recruiting, to our team. These two reviewed resumes and provided guidance on careers. As an added bonus, they assisted some job-seekers get interviews and eventually placements within the pharmaceutical and biotech industries even in locations such as Kansas.

I am also grateful to the Northeastern YCC for organizing a highly successful Career Fair For their innovative efforts with such large attendance and benefits to local area members. The YCC has been an extraordinarily active and proficient group; the officers and membership have to be complimented for their innovative contributions.

The “Advances in Chemical Sciences Symposium”, was held on April 11, 2008: it was a spectacular success. The symposium, a day-long celebration of Chemistry was held at the Royal Sonesta Hotel in Cambridge, MA. Under the auspices of this conference, eminent scientists delivered plenary lectures. The conference brought together 300+ scientists for a scholarly event focusing on medicinal chemistry, organic synthesis and methodology. The plenary lecturers were Magid Abou-Gharbia, (Wyeth), Mark Goulet, (Merck Research Laboratory), Timothy F. Jamison, (Massachusetts Institute of Technology) John Piwinski, and (Schering Plough). Mathew Shair, (Harvard University), Eric J. Sorensen, (Princeton University). The topical focus areas – medicinal chemistry, pharmaceutical and organic synthesis are areas where the chemical enterprise in our area has a well deserved reputation for excellence.

A large number of pharmaceutical and biotechnology industry professionals from the metropolitan area joined us for this event, shared ideas and built networks. The response has been extremely enthusiastic. A

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sell out symposium crowd was treated to some exhilarating science from some of the finest practitioners of the discipline. A vendor show has already drawn 16 vendors. The symposium is co- sponsored by the US (East Coast) Section of the RSC, and IUPAC. This helps cement our relationships with our colleagues from other societies. Represented on the organizing committee were scientists from many of the Pharma companies in our area. We thus continue to build a nucleus for the future: there is a lot of enthusiasm for having this as an annual event. Our new Chair-elect is a distinguished member of the pharmaceutical community in our section.

Mukund S. Chorghade President Chorghade Enterprises 14 Carlson Circle Natick, MA 01760-4205 Tel: 508-651-7809 Fax: 508-651-7920 Cell: 508-308-3891 [email protected]

REPORT OF THE CHAIR–ELECT / PROGRAMS - 2008 E. Joseph Billo

As Program Chair, the Chair–Elect organized those monthly meetings of the Section (speakers, venues, etc.) that were not otherwise within the purview of the special awards committees (Richards Medal, Esselen Award, Norris Award) and the Medicinal Chemistry Group.

Date Program

January 10 Monthly Meeting - Holiday Inn, Brookline, MA Dr. Hannah Sevian, University of Massachusetts Boston Topic: Incremental Movement Toward an Inquiry Lab Curriculum in General Chemistry: Can Changing a Single Laboratory Experiment Improve Student Performance? February 14 Monthly Meeting – Simmons College, Boston, MA Joint Meeting with NOBCChE Dr. Joyce P. Foster Director of Academic Resources, Williams College Dr. Valerie P. Wilson Associate Dean of the Graduate School, Brown University Topic: Mentoring Matters Across the Diverse Populations in the Academy March 13 Monthly Meeting - Harvard Faculty Club, Cambridge, MA T. W. Richards Medal for Conspiculous Achievement in Chemistry Prof. Robert G. Bergman, University of California at Berkeley Topic: Selective Organic and Organometallic Transformations Mediated by Molecular And Supramolecular Environments April 17 Monthly Meeting - Harvard University Gustavus John Esselen Award Dr. John A. Katzenellenbogen, Swanlund Professor of Chemistry University of Illinois at Urgana-Champaign Topic: Estrogens and Estrogen Receptors as a Nexus of Chemistry and Biology in Health and Disease

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May 8 Monthly Meeting - Northeastern University, Boston Education Awards Prof. Angela Belcher, M. I. T. Topic: From Nature and Back Again . . . Giving new life to materials for energy, electronics and the environment Presentation of Awards: Philip L. Levins Memorial Prize Norris/Richards Undergraduate Research Fellowships Undergraduate Grants-in-Aid Project SEED Certificates Richards Secondary Teaching Awards Aula Laudis Society - Induction of Members Ashdown Examination Prizes Simmons College Prize Phyllis A. Brauner Memorial Book Award September 11 Monthly Meeting – Joint meeting with Medicinal Chemistry Group Medicinal Chemistry Group Symposium – Boston College, Chestnut Hill, MA Topic: New Developments in Anti Infective Research Moderator: Dr. Norton Peet, No. Andover, MA Speakers: John Williams, Sr. Research Investigator, Microbiotix, Worcester, MA Nucleosides and the Challenge of Antivirals: ZSM-I-62 as a Candidate Anti-HCMV Drug Gregory S. Bisacchi, Associate Director, AstraZeneca R&D, Boston Antibacterial Discovery: Past, Present and Future TBD Milind Deshpande, Executive Vice President and Chief Scientific Officer, Achillion Pharmaceuticals, New Haven, CT Isothiazolopyridones and Isothiazoloquinolones: Discovery of Potent Antibacterial Agents for Treatment of Highly Drug-Resistant Pathogens October 15 Monthly Meeting – Henderson House, Weston, MA Henry A. Hill Award for Outstanding Service to the Northeastern Section to Dr. Michael Singer 50-Year Members of ACS presented certificates of recognition Dr. Peter Meltzer, President, Organix, Inc., Woburn, MA The Establishment and Evolution of a Small Chemical Business in Massachusetts November 8 Monthly Meeting / Brandeis University Faculty Club, Waltham, MA James Flack Norris Award Dinner & Program Prof. David K. Gosser, Jr., City College of New York Prof. Jack A. Kampmeier, University of Rochester Prof. Pratibha Varma-Nelson, Indiana U.-Purdue U. Topic: Peer-led Team Learning December 10 Monthly Meeting – Joint meeting with Medicinal Chemistry Group Medicinal Chemistry Group Symposium – Holiday Inn Hotel, Woburn, MA Topic: New Technologies for Drug Discovery Moderator: Dr. Norton Peet, International Consultant, No. Andover, MA Speakers: Klaus van Leyen, Harvard Medical School, Charlestown, MA New Drugs for Stroke: What to Do? John A. Porco, Jr., Boston Univ. Chemical Methodology & Library Development Center, Boston New Approaches for Discovery of Chemical Reactions and Chemotypes Scott L. Harbeson, Concert Pharmaceuticals, Lexington, MA Selective Deuterium Chemistry in Drug Discovery: Improved New Chemical Entities Frm Clinically Validated Therapeutics Christopher G. Newton, BioFocus DPI, Chesterford Research Park, Essex, UK Drug Discovery in the 21st Century -- The Collaborative Paradigm

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Photos from Sample Monthly Meetings Additional photos may be found in related reports.

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BOARD OF PUBLICATIONS REPORT FOR 2008 Mary A Mahaney, Chair

The Board of Publications (BOP) is responsible for oversight and management of both the Nucleus and the NESACS website. The Chair of the BOP also serves as the Chair of the Arno Heyn Memorial Committee.

The members of the Board of Publications of the Northeastern Section of the American Chemical Society (NESACS) for the year 2008 consisted of three voting members: Mary Mahaney, Chair; David Cunningham, Secretary and Webmaster; Vivian Walworth and six nonvoting members: Mike Filosa, Nucleus Editor; Myron Simon, Associate Nucleus Editor; Stefan Koenig, Assistant Editor; Mindy Levine, Assistant Editor; Vince Gale, Advertising Manager; and Karen Piper, Business Manager.

Mary completed her 3-year term at the end of December, 2008, and has been re-appointed to the BOP. As of January 1, 2009, David Cunningham will become BOP Chair while continuing to serve as the NESACS webmaster. Vivian Walworth will serve as Secretary. Mary Mahaney will continue as a voting member of the BOP. Vince Gale will continue as Advertising Manager and Karen Piper as Business Manager of The Nucleus.

The Arno Heyn Memorial Book Prize for 2008 was awarded to Vivian Walworth for her many significant contributions to the publications of NESACS. The presentation took place at the November NESACS meeting. Arno Heyn’s son Robert and his wife, Janice, attended that meeting as guests of the Section.

NUCLEUS REPORT FOR 2008 Mike Filosa, Nucleus Editor

Overall 2008 was a good year for the Nucleus in terms of content. The number of pages printed was up to 220 for the year exceeding the 208 pages published in 2007 and the 192 pages published in 2006. The uptick in pages was as a result of two factors. First, we had an exceptional year for editorial submissions. We benefitted from four excellent submissions by our Summer Scholars as well as Professor Robert Bergman’s Richards Award Address and Professor John Katzenellenbogen’s Esselen Award Address. Megan Driscoll also contributed a four part series on “Interviewing in the Biotech Industry” which appeared in four consecutive issues. We also benefitted from our more standard contributions: several book reviews by Dennis Sardella, features and photos by Morton Hoffman, historical notes by Myron Simon, photos by James Phillips, NCW related information and reports from Christine Jaworek-Lopes, Ruth Tanner’s submissions as chair of the Education Committee, and a substantial increase in articles and announcements from the Northeastern Section YCC. The editor was particularly pleased at these submissions and all of the other submissions to the Nucleus, major and minor, in 2008. Secondly, we benefited from a significant increase in advertising this year, which not only contributes added dollars of revenue but also adds pages of content.

In addition to the contributions listed above, it takes a team to deliver the completed Nucleus to the printer. Sheila Rodman continued to shepherd the calendar each month. Vivian Walworth and Don Rickter supplied the bulk of the proofreading during the year. Harvey Steiner of Art Related Technologies converts the text documents and rough layout of the editor into the final Quark document supplied to the printer and the final Adobe document delivered to the webmaster. Bob Kuchniki and Saltus Printing of Worcester finished the process of proofing, printing, assembly and mailing.

At the end of the year we welcomed two new volunteers as assistant editors of the Nucleus: Stefan Koenig of Sepracor and Mindy Levine of MIT. Their interest in contributing is both greatly appreciated and necessary. The Nucleus has already improved as a consequence of their efforts.

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The one down point of the year was substantially increased costs for printing and layout. Each of these services exceeded the 2008 budgeted amounts by approximately $3000 resulting in expenses over $6000 above those in the original budget. This was partially offset by increased advertising income resulting in an overall deficit of $3100. The plan in 2009 is to carefully watch expenditures from the beginning of the year to both eliminate any deficit and to deal with a budget reduction. This budget reduction is a consequence of the difficult economic environment expected in 2009.

NESACS WEB SITE REPORT FOR 2009 David Cunningham, NESACS Webmaster

Dr. David Cunningham, BOP secretary and NESACS webmaster has been actively involved in guiding the development of the web site. Our professional web consultant, Mr. Roy Hagen’s, implementation of the vision of the web master and BOP, as well as his efficiency have resulted in a professional site appropriate to the ACS. David and Roy worked diligently to enhance the web site and keep it accurate and up-to-date. Typically new information has been posted on the same day that it was received by the webmaster.

The sites graphic layout has been improved and drop-down menu tabs have been added, making it easier to find information quickly, and making the site a worldwide showcase for the section. Several new features, designed to provide value to our members are under development. These include audio enhanced monthly meeting speaker Power Point™ presentations, podcast(s), and active web links to our sponsors.

New and archived issues of the Nucleus were the most viewed and downloaded files on the site. Interestingly archived issues continue to be as popular as current issues. It appears that archived issues continue to be of interest, giving newer issues relatively fewer downloads than more current issues due to their shorted posting durations. Other commonly downloaded files include: the calendar, board meeting minutes, board member listings, and past annual reports. Access to NESACS activities and information are of significant interest and value to our audience. The popularity of the Nucleus on the web, particularly older archived editions, needs to be considered carefully with respect to advertising and content considerations.

An effective web presence with high value content for our members is essential to attract and keep new members. It is crucial that our web site accelerate its growth into new technology, including podcasts, video and audio streaming, and efforts to integrate more section members into meetings and activities through special interest pages within the site. The focus of web development for the coming year is to provide significant value to all of our members while presenting NESACS as an active and highly effective professional organization to the world.

REPORT OF THE 2008 RICHARDS MEDAL AWARD COMMITTEE Gary R. Weisman, Chair

The 2008 Richards Medal was presented to Professor Robert G. Bergman at the March 13, 2008 meeting of the Northeastern Section of the American Chemical Society (NES/ACS). Professor Bergman is the Gerald E. K. Branch Distinguished Professor at UC Berkeley and a member of the Chemical Sciences Division, Lawrence Berkeley National Laboratory. A reception and banquet honoring the awardee was held at the Harvard Faculty Club. The award presentation took place at the Pfizer Lecture Hall at Harvard University followed by the award address titled “Selective Organic and Organometallic Transformations Mediated by Molecular and Supramolecular Environments.”

The Richards Medal Committee consists of members elected by the Northeastern Section, plus the editor of the Journal of the American Chemical Society (JACS) and two ACS members from outside the Northeastern Section selected by the Richards Medal Committee Chair. The committee selecting the 2008 medalist consisted of elected NES/ACS members Prof. Gary R. Weisman of the University of New Hampshire (Chair), Prof. Paul Davidovits of Boston College, Prof. Roy G. Gordon of Harvard University, Prof. Stephen J. Lippard of the Massachusetts Institute of Technology, Prof. Daniel G.

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Nocera of the Massachusetts Institute of Technology, Prof. Dagmar Ringe of Brandeis University, ACS members Prof. Brian P. Coppola of the University of Michigan and Prof. Mary J. Wirth of the University of Arizona, and Prof. Peter Stang of the University of Utah (JACS Editor).

Profs. Davidovits, Gordon, Nocera, and Ringe are the continuing NES/ACS members of the Committee. Prof Gordon has agreed to serve as Chair through the 2010 Richards Medal award cycle.

N ORTHEASTERN SECTION AMERICAN CHEMICAL SOCIETY RICHARDS MEDAL AWARD COMMITTEE GARY R. WEISMAN, CHAIR

DEPARTMENT OF CHEMISTRY UNIVERSITY OF NEW HAMPSHIRE DURHAM, NH 03824-3598 TEL: 603-862-2304 EMAIL: [email protected]

PRESS RELEASE NORTHEASTERN SECTION OF THE AMERICAN CHEMICAL SOCIETY

January 10, 2008

ROBERT G. BERGMAN SELECTED 2008 RICHARDS MEDALIST

Professor Robert G. Bergman of the Department of Chemistry of the University of California at Berkeley has been selected to receive the 2008 Richards Medal by the Northeastern Section of the American Chemical Society (ACS). The Richards Medal is awarded every two years for conspicuous achievement in chemistry. It is the section’s oldest and most prestigious award, honoring the first U.S. Nobel laureate in Chemistry.

Robert Bergman is the Gerald E. K. Branch Distinguished Professor at UC Berkeley and a member of the Chemical Sciences Division, Lawrence Berkeley National Laboratory. He spent the first part of his career investigating the mechanisms of organic reactions and the generation and study of unusually reactive molecules. In the mid-1970's his research broadened to include organometallic chemistry. He has made contributions to the synthesis and chemistry of several types of organotransition metal complexes and to improving our understanding of the mechanisms of their reactions. Most recently he has been involved in the application of C-H activation reactions to problems in organic synthesis. He has previously received the ACS Award in Organometallic Chemistry (1986), an ACS Arthur C. Cope Scholar Award (1987), the ACS Arthur C. Cope Award (1996), and the ACS James Flack Norris Award in Physical Organic Chemistry (2003).

He has been honored with numerous other awards and is an elected member of the National Academy of Sciences and the American Academy of Arts and Sciences (both in 1984). In 2007 he was chosen by the National Academy of Sciences to receive the NAS Award in Chemical Sciences.

After completing his undergraduate studies in chemistry at Carleton College in 1963, he received his Ph.D. at the University of

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Wisconsin in 1966. After a postdoctoral fellowship at Columbia University, he joined the faculty of the California Institute of Technology, rising through the professorial ranks before moving his research group to UC Berkeley in 1978.

Prof. Bergman will be honored at an award dinner and medal presentation in conjunction with the NESACS meeting scheduled for March 13, 2008 at Harvard University. He will present an award address titled “Selective Organic and Organometallic Transformations Mediated by Molecular and Supramolecular Environments.”

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REPORT OF THE SUMMERTHING COMMITTEE - 2008 Doris I. Lewis, Chair

Committee members: Doris Lewis, chair; Michael Singer, Marietta,Schwartz, Bob Lichter.

This year’s Summerthing was a very successful commemoration of Wally Gleekman’s long association with Summerthing activities at Fenway Park. A sold-out purchase of 60 seats, many of them bought by the high school teachers from Wally’s contact list, enjoyed a day at Fenway Park with their families (see Nucleus article below). An enthusiastic Summerthing group plans expanded activities next year, with more tickets purchased and ( we hope) Summerthing hats with the NESCAS emblem honoring Wally Gleekman as well. We will continue with a plan, shelved from a very rainy summer this past year, to have a Tanglewood activity also, hosted by Bob Lichter.

Respectfully submitted,

Doris Lewis, Chair

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REPORT OF THE TREASURER AND AUDITOR - 2008 James U. Piper, Treasurer

Page 1 of the financial report reflects the transactions in the operating account of the Section. In addition to the operating account, the Trust Funds operate under the supervision of the Board of Trustees. The operating account generally pays all bills and then requests reimbursement of Trust-related expenses from the Trustees. In 2008, those reimbursements totaled $63,481.20 (line 10). Since the Trust funds are separately maintained, the calculation of the Public Support ratio is shown in the notes to line 33.

The Section operating account ran an operating deficit of $11,326 in 2008. However, the reimbursements due from the Trust Funds increased by about the same amount as the deficit: at the end of 2007, $16,779 was owed to the Operating Account by the Trust accounts for expenses incurred during the year while the amount due had increased to $28,225 at the end of 2008. Consequently, operating income and expense were essentially balanced.

A separate set of books is kept for the Nucleus, and these are maintained on an accrual basis. The financial results presented by the Board of Publications differ from those in the Treasurer’s report because the latter is presented on a cash basis. On an accrual basis, the Nucleus had advertising revenue of $45,497 and expenses of $76,866. The deficiency is funded by Section general funds, the Publications Trust and the Norris Trust.

The Attorney General of the Commonwealth of Massachusetts requires nonprofit organizations to file annual reports accompanied, in our case, by a review by a CPA. The review of the 2007 financial statements was completed in August, and the report was filed. Copies of forms 990 and 990T for 2007 were sent to the National ACS office.

James U. Piper Treasurer

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REPORT OF THE BOARD OF TRUSTEES - 2008 Esther A. H. Hopkins, Joseph A. Lima, Michael E. Strem

The Trustees of the Section for the year 2008 were Esther A. H. Hopkins, Michael Strem and Joseph Lima. We met with our financial consultant, Robert M. Sarly, Senior Vice President at Smith Barney, Inc., held informal meetings, received reports from Smith Barney and from Piper Enterprises and discussed recommendations for the Board as to uses for the Funds in our care in keeping with the wishes of the donors of the funds.

The Trust Funds of the Northeastern Section are in three Trust Accounts and six income accounts. The Trust Accounts are (one)—the Consolidated, comprising the principal amounts of the Richards, the Norris, the Publication, the Permanent, the Hill and a portion of the Brauner trusts, (two)—the Esselen Trust, and (three)—the Levins Trust. To keep the capital ratios constant in the Consolidated Trust, capital amounts withdrawn from it are distributed to the Income accounts in the ratio of their ownership.

The Consolidated Account for 2008 had an opening portfolio value of $2,039,626.68. In 2007 the account had been divided into three parts, one of which is an actively managed account, the second a comparable Trustee- managed account, with the remainder of the assets in the parent account. Withdrawals from the Consolidated Account consisted of $40,000 in distributions to the income accounts and 16,010.42 of expenses. The adjusted opening balance was, therefore, $1,889,078.44. The closing balance was $1,358,394.44 for a decrease of $530,684.00. This represents a loss of 28%. The Consolidated Trust contains money funds, common stocks, exchange traded & closed end funds, mutual funds, and corporate bonds. The current yield at year-end was 7.75% and the annualized anticipated income was $94,304.

The Esselen Fund, comprising money funds, mutual funds and government bonds, had an opening balance of $536,662.13. $16,000 was withdrawn for the expense of the award this year. The adjusted opening value was $520,662.13 and the closing value was $544,810.26. The Levins Fund, comprising money funds, exchange traded & closed end funds, and mutual funds had an opening portfolio balance of $11,066.81. No expenses were withdrawn during the year. The closing portfolio value was $6,791.38. The Brauner Trust “income account” comprised of money funds, common stock and exchange traded & closed end funds had an opening balance of $27,617.97. Distributions of $830.84 were deposited to the Fund and $2,000 was withdrawn for the previous year’s lectures, giving an adjusted opening balance of $26,448.81. The closing value was $22,320.17 of which $6,333.44 was income and the remainder was Trust principal.

The Hill income account comprising money funds and exchange traded & closed end funds had an opening portfolio value of $18,969.64, received $1,997.64 from the prorated distribution from the Consolidated Account and distributed $1,286.72 to the Section for expenses, for an adjusted value of $19,680.56. The closing value was $14.094.39. The Norris Award income account, comprising only money funds had an opening portfolio value of $1,847.94 and an adjusted value of $1,384.21 after receiving 23,335.76 from the prorated distribution and withdrawing $23,799.49 for expenses. The closing portfolio value was $1,440.57. The Permanent income account, comprising money funds, common stocks and exchange traded & closed end funds had an opening portfolio value of $62,967.33, received $5,777.32 from the prorated distribution and withdrew $8,004.53 in expenses for an adjusted value of $60,740.12. The closing value of the portfolio was $44,957.60. The Publication income account, comprising money funds, common stocks and exchange traded & closed end funds had an opening portfolio value of $56,655.20, received $3,265.88 from the prorated distribution and withdrew $8,000 in expenses for an adjusted value of $51,920.88. The closing value was $34,367.41. The Richards income account, comprising money funds and exchange traded & closed end funds had an opening value of $39,431.59, received $4,792.76 from the capital distribution, withdrew expenses of $11,668.34 for an adjusted value of $32,556.01. The closing value was $21,016.18.

Respectfully submitted, The Trustees Esther A.H. Hopkins Michael Strem

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Joe Lima

Younger Chemists Committee Reports - 2008 Laila Dafik and Leland Johnson

A Report on NSYCC Activities Connect, Talk and Elect, but are you 35? By Laila Dafik – NSYCC Chair (07-08)

2008 German-NSYCC Exchange

The German Chemical Society (Gesellschaft Deutscher Chemiker, GDCh), and its Young Chemists Forum (Jung-Chemikerforum, JCF), welcomed to Germany 12 representatives of the NESACS Younger Chemists Committee (YCC) who had been selected by the German Exchange program steering committee. The delegates were accompanied by Prof. Ruth Tanner (University of Massachusetts Lowell), Prof. Mort Hoffman (Boston University- Professor Emeritus) Mike Strem (Strem Chemicals) and Dr. Bob Lichter (Merrimack Consultants, LLC). The visit came as the eight annual exchange program between the NESACS-YCC and GDCh-JCF, highlighting the close connection between the NESACS and the GDCh.

The weeklong program began on Wednesday, March 26th, with a day in Rostock and a tour of Rostock University. On Thursday Wendy Iskenderian (MIT) spoke in Frühjahrssymposium about her research. At the end of the day, a poster session was held where the American graduate and undergraduate students displayed their research posters and discussed their scientific progress. In addition, on Friday two students, Brett Fors (MIT) and Raymond Moellering (Harvard University), contributed oral presentations while the rest of the American group discussed their posters. At the end of the day, Frühjahrssymposium hosted a dinner coupled with a social evening where the American contingent had the opportunity to network with their German peers. On Saturday morning, Patrick Cappillino (Boston University) gave an oral presentation and received the third place award for best oral presentation. In addition, Shuyu Wang (Harvard University) was awarded a prize for best poster presentation.

In addition to the scientific talks, the program included a four-day stay in Hamburg, where students had the chance to visit Hamburg University and local laboratories such as Dow Chemical. At the end of the week, Dr. Kurt Begitt, Deputy Executive Director and Director of Education and Professional Affairs of the GDCh accompanied by representatives of the Young Chemists Forum (Jung-Chemikerforum,JCF) hosted a farewell dinner in honor of the American delegation. Looking ahead to the 2009 exchange program, the application will be available at the end of the summer. A delegation from NESACS will travel to Essen, March 11-18 for the Frühjahrssymposium. We hope that NESACS-YCC and GDCh-JCF exchange continues and we look forward to greeting JCF to Boston in August 2010.

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2008 Northeast Student Chemist Research Conference (NSCRC)

Following the German Exchange Program 2008, the Northeastern Section Younger Chemists Committee (NSYCC) and its local Tufts YCC organized the tenth annual Northeast Student Chemist Research Conference on Saturday April 19th at the Chemistry Department of Tufts University. The keynote speaker was Professor Stuart L. Schreiber from the Broad Institute with a lecture titled “Small-molecule Probe and Drug Discovery”. The one day long conference consisted of oral presentations given by the younger chemists from the Northeastern region followed by a poster session where participants discussed their research with their peers and were judged by a NSYCC judging committee. This year’s NSCRC distributed eight awards.

2008 NSCRC awardees Carl Christianson (Boston College) - Strem Excellent Oral Presentation Award Erin Iski (Tufts University) - Vertex Excellent Oral Presentation Award Adam Schell (Boston University) - Vertex Excellent Undergraduate Research Award Margaret Thompson (Wellesley College) - NESACS/YCC Excellent Undergraduate Research Award Raymond Moellering (Harvard University)- Vertex Excellent Graduate Research Award Gülbenk Anarat (Boston University)- NESACS/YCC Excellent Graduate Research Award Jeffrey Garber (Darmouth College) - The Brauner Book Award Wendy Iskenderian (MIT)- GWIS Award

2008 NSYCC elections

For the first time, elections for the 2008-2009 NSYCC officers were held on Saturday May 31, 2008 at the Chemistry department of Tufts University. The elections were organized by the Tufts Younger Chemist Committee. This first round of elections generated new positions such as publicity and social vice-chairs. The publicity co-chairs will be solely responsible for advertising and reaching out to the entire Northeastern Section. Another noteworthy outcome of the election was the appointment of a vice-chair who would help with the committee tasks and activities planning. This event marked the beginning of a new tradition, an annual conference followed by a round of elections for future NSYCC officers, who are not necessarily under 35. Being an ACS member and under 35 seems to be no longer a limitation to becoming a position holder in the committee. If the present committee or the future one decides to implement the National Younger Chemist guidelines, the question is, does being older than 35 matter? For more information about the present committee please refer to our website www.nsycc.org. _

The NSYCC, Spring 2008, and Beyond…

This account was submitted by incoming Chair, Leland (Lee) Johnson ([email protected], Novartis-NIBR), with contributions by incoming Vice-Chair Deniz Yüksel (Tufts), and incoming Career Chair Lynell Skewis (Boston University). Note that while the German Exchange is one of our most important programs, details of this year’s exchange will be submitted for next month’s The Nucleus.

For the past three years, we each have been involved with the NSYCC and our respective university YCCs. During this time, a real effort has been made to improve upon the successes of our predecessors. We have the proverbial “big shoes to fill,” considering the strong past leadership of Amy Tapper, Lauren Wolf, Ivan Korendovych, and most recently, Laila Dafik. Centered around networking and professional development of younger chemists in the North-eastern Section, the committee’s activities have been heavily concentrated around certain key spring events, including the German Exchange, the Northeast Student Chemistry Research Conference (NSCRC), the Northeast Student Chemistry Career Fair (NSCCF), as well as YCC social events. These programs have focused on bringing

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together younger chemists still in school with their counterparts in professional careers in industry and government. This spring, the committee, under the direction of Laila Dafik (Tufts), executed several successful events. For example, Alex Taylor (MIT) headed up a social event at Flat Top Johnny’s in Cambridge’s Kendall Square. Alex relied on word-of-mouth and the growing NSYCC emailing list to advertise the event. Eight two-person 8-ball teams competed to the bitter end, making networking connections and enjoying appetizers and refreshing beverages for a few hours one evening in April. Cash prizes were awarded to the top two teams, and overall, the event was a great success. For the next pool tournament, we hope to have greater participation by some of our area younger chemists in the pharmaceutical and biotech industry.

During the buildup to this year’s NSCRC at Tufts University, planning took place on the Tufts campus. Laila Dafik led the effort, reserving rooms, space, and contacting professors who might be available to share their work with the NSYCC. Deniz Yüksel has played an increasingly greater role in planning this annual event since her first association with the NSCRC in 2006. Held at MIT in 2006, Deniz volunteered at the registration desk and presented a poster. According to Deniz, since 2006, there has been a tremendous improvement in the organization of the conference and, pleasantly, higher attendance. For the past two years, there have been scores of posters and eight oral presentations each year. We have been fortunate to have several major sponsors of the NSCRC, including Vertex Pharmaceuticals (2007, 2008), AstraZeneca (2007), Strem Chemicals, NESACS, Graduate Women in Science (GWIS, Alpha Omega Chapter), the Broad Institute (2008), Pfizer (2007), and Ziopharm Oncology (2007). For their dedication to the regional younger chemists, the NSYCC would like to thank the friends of the YCC at each of these companies and organizations. Because of these very generous financial gifts, the NSYCC was honored to host Professor Stuart Schreiber (the Broad Institute) who gave his keynote lecture entitled “Small- Molecule Probe and Drug Discovery”. Following his informative lecture, the NSYCC presented the following monetary and memorial awards (sponsors listed): Carl Christianson (Boston College) - Strem Excellent Oral Presentation, Top Award Erin Iski (Tufts) - Vertex Excellent Oral Presentation Award Adam Schell (Boston University) - Vertex Excellent Undergraduate Research Award Margaret Thompson (Wellesley)- NESACS/NSYCC Excellent Undergraduate Research Award Raymond Moellering (Harvard) - Vertex Excellent Graduate Research Award Gülbenk Anarat (Boston University) -NESACS/NSYCC Excellent Graduate Research Award Jeffrey Garber (Dartmouth College) - The Brauner Book Award Wendy Iskenderian (MIT) - GWIS Award

A few years back, I was appointed to the position of Career Chair, and I immediately identified certain challenges facing the organization. Establishing, re-establishing, and maintaining a network of YCC supporters in the regional corporate community was one big hurdle to clear; the other was convincing corporations that the NSYCC, an organization run completely by younger chemist volunteers, was able to provide real value in recruiting new hires for positions in industry and publishing. I believe we have made significant progress on both of these fronts. Last year, the pharmaceutical and biotech economy seemed to be in great shape, the corporate forecasts for hiring were also good, and the real challenge was re-establishing communications with, what turned out to be, multiple moving targets. Lists of corporate contacts were a great place to start, and I remember starting with a contact at a well- known pharmaceutical company located very close to the Alewife T-station. His name was on the contact list, and their logo was online as a recruiting sponsor from previous years, so I gave a call…no answer, voicemail. Thankfully, this scientist left an alternate contact number on the voicemail greeting, so I tried again. As it turned out, Steve Tam (Wyeth) was quite a sport, taking my call and talking with me at length about Wyeth continuing their recruiting sponsorship at the 2007 other recruiting sponsors in 2007, enabling the NSCCF to be “in the black,” for the first time in years. We did this with a lot of work from NSYCC volunteers from several regional universities, as well as help from faculty and staff from colleges and universities within, and adjacent to, the Northeastern Section. The contacts initiated in 2007 have paid dividends again this year. In early 2008, however, the economy and hiring environment had changed, and prospects for securing recruiting corporations for the Career Fair seemed pretty bleak. We decided to offer more value to our recruiting sponsors, with pre- and post-event online resume access, free parking at the event, and data CDs of resumes, to name a few. Our recruiters came from

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past lists, new phone calls, and responses to our announcements in The Nucleus. Recruiters this year included Adante Staffing, the Broad Institute, CreaGen Biosciences, Eisai (ERI), PCI Synthesis, Merck, Nature Publishing Group, and Sigma-Aldrich. As in the past, job seekers could also use the event to learn a bit about the job-seeking process. The ACS Career Services team, led by Dan Eustace, provided valuable and sometimes eye-opening advice regarding resume writing, interview preparation and techniques, as well as turning unexpected (bad) news from interviews into a positive learning experience. While the number of NSCCF job seekers and recruiting corporations was down from 2007, the overall event was still a success. One-on-one conversations between motivated job seekers and corporate recruiters, small group analysis and demonstration of interview skills, and personal attention to resumé content and style ruled the day. The number of younger chemist organizers and volunteers for the event increased from 2007, including UMass Boston, UMass Dartmouth, and Boston University YCC members. We would again like to thank NESACS, the corporate recruiters, the corporate representatives, and job seekers for their participation this year.

So, what’s next? Overall, the NSYCC executive committee wishes to honor our past leaders by building on the excellent foundation established during their tenures. We will expand our social activities, aiming for events that are interesting to younger chemists of all types, whether in school or out. Currently, our executive committee is focusing on several key goals (and accepting suggestions and new ideas on our website, (http://www.nsycc.org). First, we seek to connect and reconnect with our section’s academic institutions. We will also build our network of younger chemists who have already started their careers. Be ready, as we will be e-mailing! As for next year, we will move toward an integrated set of spring activities. Returning to a two-day symposium on networking, professional development and career building may help our sponsors and our members more efficiently accomplish their individual goals without breaking corporate budgets for recruiting, discretionary YCC support, or personal bank accounts. Specifically for the NSCRC, we would like the keynote lecture selection to come from the area’s younger chemists. As a student- invited lecture, Deniz ([email protected]) has joined the committee with this as one goal for the NSCRC. With a student-invited lecture, the selection of professors will be limited only by the number of individual suggestions. We all agree that the NSCRC has the potential to become a premier chemistry student symposium, and to this end, the publicity and social committees have dedicated their focus to establishing and expanding networks while executing a plan to keep the attendees and the sponsors pleased by the number of participants and the breadth of activities offered.

For the 2009 NSCCF, Lynell has a plan to increase the scale of the event, to provide expanded career opportunities for younger chemists in our section, and provide sponsoring companies with a pool of strong job applicants. To do this, she intends to build upon the already growing network of corporate contacts built over the past several years by Lee Johnson and his predecessors. In doing so, she will continue the important work by reaching out to regional companies that employ green, inorganic, physical and computational chemists. She is actively seeking contacts ([email protected]) in the corporations in the area that generally spend thousands of dollars recruiting. These corporations will find that a small investment in the NSYCC could potentially save thousands of dollars in recruiting per applicant. The NSCCF offers the opportunity to meet these applicants before offering an on-site visit. By seeking corporate sponsors of the organization, instead of one event here and one event there, the NSYCC hopes to minimize paperwork and give transparency to our budget in an effort to reassure our corporate sponsors.

To increase the number of younger chemists as participants and registrants, our committees will, with the help of the NSYCC publicity chairs, reach out to all of the colleges and universities in the section. Specifically, Lynell seeks to engage graduate and undergraduate student leaders in chemistry at colleges and universities in the section who have not yet fully benefited from the NSYCC functions in the past. Unfortunately, younger chemists, their corporate and academic advisors and representatives may not be aware of the opportunities available to them through the NSYCC. In an effort to keep our goals innovative and fresh, our leadership must be cultivated on an ongoing basis.

To make our annual leadership transitions as smooth as possible, the NSYCC has pledged to adopt a consti-

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tution over the summer. The continuity offered by a functional governing document, coupled with motivated leaders seeking well-defined positions, will keep the NSYCC moving forward. As mentioned, the NSYCC executive committee has devised a plan to integrate our growing networks of volunteers, members, recruiters, and sponsors. This is where we need the most assistance and support from the chemists in the geographic area within and around the Northeastern Section. As many have found, establishing and maintaining functioning networks which include a dynamic membership is a difficult task. We thank everyone again, and we encourage volunteers, members, sponsors and recruiters to contact us whenever they have a question or comment. We look forward to growing the NSYCC with your help.

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ANNUAL REPORT Northeastern Section, ACS

APPENDIX 5-A

SPECIAL PROGRAMS (Web Pages)

Northeastern Section Chemistry Research Conference Undergraduate Research Symposium / BSC

http://www.nesacs.org

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NSCRC 2008 Saturday, April 19, 2008

Department of Chemistry, {Directions}

Tufts University,

Medford, MA-02155.

Deadlines for submission (5 PM): April 8, 2008 for oral presentations, April 11, 2008 for poster presentations. Please note: poster size is 4' x 4'. ** REGISTRATION FOR THE CONFERENCE IS CLOSED ** If you have questions about templates or abstract submission, contact T K Subbu [e-mail] PROGRAM SCHEDULE

8:00 AM - 9:00 AM Poster Set-Up, Registration and Breakfast 9:00 AM - 9:15 AM Welcoming Remarks by Laila Dafik 9:15 AM - 9:30 AM German Exchange Update-Rostock, Germany, March 2008 by Wendy Iskenderian, MIT 9:30 AM - 9:50 AM Mark M. Chen (MIT) "Polyisoprene Specificity in N-linked Glycosylation" 9:50 AM - 10:10 AM Patrick Ng (Northeastern University) "Methodology for the Preparation of PET Imaging Ligands" 10:10 AM - 10:30 AM Erin Iski (Tufts University) "AgCl Monolayers on Au(111): Novel, Ultra-stable and Atomically-flat Surfaces"

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10:30 AM - 10:45 AM Coffee Break 10:45 AM - 11:05 AM Sanghamitra Mitra (Boston University) "Impact of sequence and structure on the redox properties of thioredoxin and glutaredoxin" 11:05 AM - 11:25 AM Darin Bellisario (Tufts University) "Temperature Effects on the Formation of Dialkyl Sulfide Self-Assembled Monolayers on Au(111)" 11:25 AM - 11:45 AM Carl Christianson (Boston College) "Probing the mechanism of a tyrosine 2,3- aminomutase from enediyne natural product biosynthesis" 11:45 AM - 12:30 PM LUNCH 12:30 PM - 12:50 PM Shuyu Wang (Harvard University) "Capturing AlkA in Action: X-ray Crystallography of a DNA Repair Glycosylase With Unusually Broad Substrate Specificity" 12:50 PM - 1:10 PM Jeffrey Garber (Dartmouth College) "Amphiphilic Block Copolymers Precursors to Cobalt Polymer Hybrids" 1:10 PM - 2:45 PM Poster Session - Remis Sculpture Court, Aidekman Arts Center 2:45 PM - 3:00 PM Poster Take-Down 3:00 PM - 3:20 PM Break 3:20 PM - 4:20 PM Keynote Lecture - Professor Stuart Schreiber, The Broad Institute "Small-Molecule Probe and Drug Discovery" 4:20 PM - 4:50 PM Awards Presentation 4:50 PM - 5:00 PM Closing Remarks

7th Annual New England Undergraduate Environmental Research Symposium

Saturday, November 15, 2008 9:00 AM - 3:00 PM Bridgewater State College - John Joseph Moakley Center COMPLETE PROGRAM AND POSTER ABSTRATCS (pdf)

Symposium Theme: "Water: Regional and International Issues"

Guest Speakers: Dr. Ellen Douglas Environmental, Earth and Ocean Sciences, College of Mathematics and Science, UMASS- Boston "Issues in Water Resources from New England to the Globe"

Dr. Kevin Curry Department of Biology, Bridgewater State College "One Filter at a Time: Health and Pure Water for Cambodia"

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SPONSORS Office of Undergraduate Research Center for Sustainability Northeastern Section of the American Chemical Society

Bridgewater State College will host the 7th Annual New England Undergraduate Environmental Research Symposium on Saturday, November 15, 2008. Undergraduate research posters (including completed, in progress, and proposed research) in all environmental disciplines from colleges and universities in the Northeastern U.S. are welcome! Since its inception in November 2001, the Symposium has averaged 100 attendees and over 40 student poster presentations. This Symposium provides an annual forum for discussion of issues related to environmental research and education particular to the New England region, and has opened doors to collaborations in research and education among the participants.

To help defray costs a registration fee of $15 will be collected on-site. For additional information or to be added to our email distribution list, please contact the Symposium Coordinators: Ed Brush, Department of Chemical Sciences ([email protected]), 508-531-2116 Tammy De Ramos-King, Department of Chemical Sciences ([email protected]), 508-531-2115 Kevin Curry, Department of Biological Sciences ([email protected]), 508-531-2082

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http://www.bridgew.edu/Environmental/PDF%20docs/2008%20Complete %20Brochure.pdf

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ANNUAL REPORT Northeastern Section, ACS

APPENDIX 6

YOUNGER CHEMISTS COMMITTEE

http://www.nesacs.org

The report of the Younger Chemists Committee will be found in Appendix 5. The NSYCC will not be submitting a self-nomination for a ChemLuminary Award for 2008.

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ANNUAL REPORT Northeastern Section, ACS

PART III

ANNUAL FINANCIAL REPORTS

Financial Reports are included below and uploaded into S.O.L.A.R.

http://www.nesacs.org

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ANNUAL REPORT Northeastern Section, ACS

PART IV

SELF-NOMINATIONS FOR CHEMLUMINARY AWARDS

Outstanding Performance by a Local Section - Very Large Size Category ChemLuminary Awards for National Chemistry Week
Outstanding Event for the General Public Using the Yearly Theme
Outstanding Event for a Specific Audience
Outstanding On-Going NCW Event

http://www.nesacs.org

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ChemLuminary Award Nomination - 1

ACS Award for Outstanding Performance by Local Sections

Contact Person Name: Marietta Schwartz

Address: Dept of Chemistry, UMass Boston, 100 Morrissey Boulevard, Boston MA 02125

Phone: 617-287-6146

Fax: 617-287-6030

Email: [email protected]

Description:

The Northeastern Section had another excellent year. Our National Chemistry Week activities were outstanding as usual. Bassam Shakhashiri’s highly acclaimed magic show was presented at the Museum of Science, NCW volunteers were at the Boston Children’s Museum performing demonstrations and assisting in hands-on activities related to the year’s theme. The section also participated in the unique sneaker recycling program sponsored by Nike. Area students had the opportunity to submit entries for the NCW poster competition, and two themed puzzles (a Sports Word Square and Elemental Sudoku) were published in the October edition of The Nucleus. Earth Day activities were another highlight of the year. On April 22, 2008, NESACS partnered with the Massachusetts Bays Estuary Association (MBEA) and the Malden High School Chemistry Club for a daylong event at the Boston Children’s Museum. More than 2000 individuals visited the museum that day. The MBEA provided an Enviroscape Model and demonstrated how pollutants from our homes ultimately end up in our water supply.

Recognizing the continuing importance of an electronic presence, our section continued to improve its electronic activities this year. Webmaster David Cunningham, in conjunction with the Board of Publications, significantly expanded and updated the section’s website which is available at http://www.nesacs.org. Dan Eustace, one of our members, continued to contribute to the section blog, available at http://blog.nesacs.org, focused on providing career development advice to area chemists. He has added podcasting to the blog, and it seems to be a very popular resource among our younger membership especially.

The Section continued to present its diverse portfolio of educational programming. In partnership with our vibrant Younger Chemists Committee, the Education Committee held the 10th annual Northeastern Student Research Conference. This event provides area undergraduate and graduate students a forum in early spring each year where they can present their research. 42 students presented their research in either poster or seminar formats. In addition, also in partnership with our Younger Chemists Committee, the Section continued its signature German Exchange program. This year, twelve graduate students and three NESACS members spent a week in Rostock and Hamburg. They had the opportunity to present their research and discuss it with their German counterparts. The Northeastern Section continued its longstanding high school chemistry competition (Avery Ashdown), awarded three grants of $350 to three area students to allow them to present their undergraduate research at the Spring 2008 National ACS Meeting in New Orleans, LA and made four awards (Norris/Richards Summer Scholarships) of $3250 to four area students to support their research over the summer in 2008 full-time. The Education Committee also continued its wonderful tradition of celebrating the accomplishments of student chemists in the Section at the high school,

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undergraduate, and graduate levels and high school educators through their wonderful May “Education Night” program, hosted for the fourth year in a row by the Northeastern University Student Affiliates Chapter. In all 30 students and 4 teachers were honored. The Connections to Chemistry program for high school teachers was presented for the ninth year in a row. 114 teachers from area high schools attended a daylong program full of useful and interesting information.

The active participation of the Medicinal Chemistry group in NESACS program planning continued, with three very successful symposia held during the year. Topic included: May (Cost, Speed, and Quality; Emerging Opportunities for Drug Discovery in Asia), September (New Developments in Anti-Infective Research) and December (New Technologies for Drug Discovery). These were all-day events, with many small sessions on various topics related to the overall theme of the day, a keynote speaker, and a dinner. The symposia were supported by local pharmaceutical companies and more than 400 scientists attended in total.

The Fifteenth Annual ACS Northeast Regional Undergraduate Day was held at Simmons College on Saturday, November 1, 2008. It was attended by 67 students from area colleges and universities. An inspirational keynote address by John Warner entitled “Green Chemistry: Designing a Sustainable Future with Beakers and Flasks” started the day. He challenged undergraduates, as the future of chemistry, to incorporate the principles of green chemistry into their daily laboratory practices. Other program highlights included research talks, presentations, and panels on applying to Research Experience for Undergraduate (REU) programs, and graduate schools, a résumé review session, and a graduate school / industry fair.

The second annual “Advances in Chemical Sciences Symposium” conference, held on April 11, 2008 was a spectacular success. The symposium was a day-long celebration of Chemistry and was held at the Royal Sonesta Hotel in Cambridge, MA. Under the auspices of this conference, eminent scientists from the triad of government, industry and academia delivered plenary lectures. The conference brought together 330+ scientists for a scholarly event focusing on medicinal chemistry, organic synthesis and methodology.

Overall, the Northeastern Section continues its commitment to provide a wide variety of programming and opportunities to its membership, from student activities (K-12, undergraduate, and graduate) and services such as career planning to specialty meetings such as those organized by the Medicinal Chemistry Group to community outreach for National Chemistry Week and Earth Day, NESACS members show their willingness to share their time and expertise at all levels.

2-3 Sentence Abstract for Program Booklet

The Northeastern Section had an outstanding year wisely continuing to develop and strength core programs and selectively adding new ones. Notable activities include: our National Chemistry Week and Earth Day activities, our outstanding Education programming, and the Advances in Chemical Sciences symposium.

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ChemLuminary Award Nomination - 2

Chemluminary Award Self-Nominations for NCW 2008 events

Local Section: Northeastern Award Category: Outstanding Event for the General Public Using the Yearly Theme Contact Person: Christine Jaworek-Lopes Emmanuel College 400 The Fenway Boston, MA 02115 [email protected]

Summary: As part of NCW 2008, the Northeastern Section of the American Chemical Society piloted adding a recycling event to the yearly NCW activities. In accordance with the theme, Having a Ball with Chemistry, The Chemistry of Sports, we decided to hold a sneaker recycling event at three locations – a local daycare, a local elementary school, and a local college.

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The event was publicized at a monthly board meeting, via email announcements and flyers on the College campus, as an announcement at a school assembly and as memos to parents. After the event was completed, a report was published in the local section newsletter, the Nucleus as well as a blurb in a local newspaper and in the elementary school’s newsletter.

The parents and children at the local daycare and elementary school were very excited about the event for several reasons: • they got to empty out closets; • they learned that recycling just isn’t paper and plastic; • they learned that the material would go into different types of playing fields.

Young children wanted to participate in this event by donating their new sneakers (much to their parent’s chagrin).

For our first recycling event, we were very happy with the results – we collected more than 100 pairs of sneakers at three different locations (one in the heart of Boston, in Wakefield (north of Boston), and in Braintree (south of Boston). We were able to spread the word about National Chemistry Week (and the theme) in a creative way.

Abstract: The Northeastern Section of the American Chemical Society held a Sneaker Recycling Event as part of the NCW activities. More than 100 pairs of sneakers were collected at three different locations. Parents and children learned that recycling isn’t just paper and plastic!

Ian Schwartz and Lori Conway (Head of Odyssey Day School) Photo by: Brian Carpenter

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ChemLuminary Award Nomination - 3

Chemluminary Award Self-Nominations for NCW 2008 events

Local Section: Northeastern Award Category: Outstanding Event for a Specific Audience Contact Person: Christine Jaworek-Lopes Emmanuel College 400 The Fenway Boston, MA 02115 [email protected]

Summary: On October 24, 2008, a diverse audience of 593 area high school students participated in a daylong program at the Museum of Science-Boston highlighting the Chemistry of Sports. Students were from the following schools: Abington HS, Advocates for Home Education in MA, AOK (Home schoolers in Cambridge), Arlington HS, Codman Academy Charter Public School, East Boston HS, Boston Day and Evening Academy, John D O'Bryant School, Greater Lowell Tech HS, Malden HS, Old Rochester Regional HS, Parkway Academy of Technology & Health, St. Joseph HS, Open Bible Academy. These schools are from a number of areas in eastern Massachusetts including the Boston area (Boston Day and Evening Academy, Parkway Academy of Technology & Health, Arlington HS), Mattapoisett (Old Rochester Regional HS – 60 miles south of Boston), Lowell (Greater Lowell Technical HS – approximately 40 miles northwest of Boston).

The students were split into two groups. Each group participated in two sets of activities.

The first activity involved the students attending a 45 minute lecture-demonstration given by David Sittenfeld, MoS-Boston, and Patrick Drane, Lowell Baseball Institute. David would do a demonstration and Patrick would discuss how the demonstration related to sports. For example, Dave did a demonstration involving water-lock and Patrick explained how this material could be used on sporting surfaces.

The second activity involved the students participating in hands-on activities and demonstrations related to the theme of sports. These activities occurred in the Blue Wing Well of the Museum. The activities included: • Demonstrating chemical hot and cold packs using lithium chloride and ammonium chloride • Making a UV-sensitive bracelet and discussing the importance of using sunscreen • Determining the sugar content in a variety of cereals, beverages, and candy • Conductivity of Gatorade, juice, and water • Making your own Gatorade • The chemistry behind moisture repellant materials • Make your own bouncing ball and compare the bounce of a homemade ball with a commercially-made ball

The students also had the opportunity to participate in the High School Series Optional Chemistry Problems. The questions were based on two of the activities in which the students participated. Twelve students chose to solve one or both questions. Two winners were randomly chosen and the winner received a $25.00 gift certificate to www.amazon.com and a National Chemistry Week t-shirt. The teacher of the winning students received a $25.00 gift certificate to www.teachersource.com.

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Approximately thirty volunteers were involved in either preparing for the event or assisting during the event. These volunteers were college students, ACS volunteers, a Brauner Committee member, Museum of Science staff, and Museum of Science volunteers. The Museum of Science – Boston handled the publicity for this event as the event was designed for high school students and reservations needed to be made in advance. Emails were sent to the teacher listserv informing them of the event. This event was also listed on the Museum’s educator news page. In addition, a portion of the event was open to the general public after the high school students had completed their hands-on activities. That was publicized in the daily flyer published by the Museum. In addition, there was signage at the Museum directing visitors to the event.

The students did not have to pay admission to the Museum as that was funded by Creagen Biosciences, Inc. and the Museum of Science-Boston. Local Section funds and a donation by Strem Chemicals, Inc. covered the costs associated with the hands-on activities.

This was our Section’s second High School Science Series event. In 2007, 225 students participated in the event and in 2008, 593 high school students participated. To better fit the 2008 theme, we adjusted the events in the well (removed the career-fair component and increased the number of hands-on activities). Also, the lecture demonstration was crafted towards a high school audience. Dave and Patrick discussed the outline prior to the event.

Abstract: On October 24, 2008, a diverse audience of 593 high school students attended a daylong event entitled “The Chemistry of Sports” at the Museum of Science-Boston. The students participated in the following: watched a lecture-demonstration given by David Sittenfeld and Patrick Drane, participated in hands-on activities such as make your own powerball, tour the Museum of Science.

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ChemLuminary Award Nomination - 4

ChemLuminary Award Nomination: Outstanding On-Going NCW Event

Contact Person: Dr. Ruth Tanner

Address: University of Massachusetts Lowell Chemistry Department, Olney Hall 1 University Avenue Lowell, MA 01854

Phone: 978/934-3662

Fax: 978/934-3013

Email: [email protected]

Description:

Title of the Program: Connections to Chemistry

Connections to Chemistry is a program which has been designed to connect high school chemistry teachers with the numerous educational resources and programs that are available from the American Chemical Society; the materials from CHED are highlighted.

The Connections program has been offered every year since October 2000 and this will be its 10th year. The program has been scheduled for the week prior to National Chemistry Week to promote National Chemistry Week and to encourage the teachers to involve their students in NCW activities. They are highlighted in one of the scheduled workshops in the Connections program and in the Connections printed program. Thus, for instance, the 2008 NCW theme was “Play Ball” and the workshop featured experiments with baseballs, superballs and various types of bats showing via high speed videos how the collisions occur, both bouncing and with a bat. The chemistry of the materials used in the bats and balls was linked to why and how far balls bounce and travel, and why bats of specific woods perform as they do. The complete 2008 program can be accessed at http://nesacs.org.

The program usually consists of four different hands-on and participatory workshops. These are generally in the areas of chemistry careers, chemistry computer programs, National Chemistry Week, and a current topic such as forensics, nanotechnology or engineering. All of these workshops are designed to be portable for the teachers to take back to their classrooms to increase student interest in chemistry.

Program materials for all participants are provided in a conference bag with the ACS logo. In addition, they receive a current issue of C&EN, the October (NCW) issue of the Journal of Chemical Education with open access to the Journal’s website for one month, a one-year subscription to ChemMatters, and a certificate for Professional Development credits. Dinner is also included after which there is a key note address. The 2008 program featured Thomas Lane, the- then President-Elect of the ACS. The program closes with a door prize raffle of ACS logo items, subscriptions to the Journal of Chemical Education and memberships to the Chemistry Teacher Connections (CTC).

The program is limited to 120 participants due to space limitations in the laboratory workshops. Generally, we have not been able to accommodate all registration requests. The registrants come from 75-85 different high schools, primarily from Massachusetts, but also from the surrounding states of Rhode Island, Vermont, New Hampshire,

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Maine, and Connecticut. The program is advertised on the NESACS website, in the NESACS publication, THE Nucleus, on the website of the New England Association of Chemistry Teachers (NEACT), by brochures sent out to Chemistry teachers in our participation data base and to the high schools in the data base for the Northeastern Section.

For this program, the teachers have been introduced to ACS programs and have used ACS program materials in the workshops. All of these materials and programs are readily available for them from the ACS to support their students and classroom activities. In addition, they have had the opportunity to network with many other chemistry teachers from a variety of highs schools, the opportunity to make contact with chemists from industry who are eager to support the education effort, and with chemists from various areas of academia who are actively engaged in high school/undergraduate activities. The program evaluations have been encouraging and helpful. We have received suggestions for topics for future programs and program comments such as: • The programs…are wonderful. They mix practical demonstrations of what you can do with kids with career oriented sessions which show the pathways to chemical careers. • Keep on doing what you’re doing now especially the outreach at conferences... • I always get new ideas and talking with other teachers is valuable. • Offer workshops more often. • Keep the programs coming. • I like the opportunity to talk with other chem. teachers to see what works for them • I like the content that has been presented because it translates directly into the classroom. It is very beneficial to the teachers. • Can this be expanded to an all day program, preferably on a Saturday or in the summer?

In the years of presenting this program, the program has impacted approximately 900 teachers, given that a percentage of them come yearly. In turn, it is likely that several thousand students have benefited not only directly from their teachers, but from their teachers’ new connections to chemists from industry and other academic institutions, and to the ACS.

We gratefully acknowledge the contributions of the following organizations and individuals for their support of the Connections to Chemistry programs. We would like to extend our special thanks to Burlington High School, MA for hosting this program since 2000.

Program Conference Committee Ruth Tanner, Chair, Education Committee, NESACS; University of Massachusetts Lowell Morton Hoffman, Chair, Division of Chemical Education, ACS; Boston University Steve Lantos, Chemistry Faculty, Brookline (MA) High School; Chair, High School Education Committee, NESACS

Planning and Program Associates Christine Jaworek, Chair, National Chemistry Week, NESACS; Emmanuel College Peter Nassiff, Past-Chair, NEACT; Head, Science Division, Burlington High School Arthur Fallon, Head, Media Services, Burlington High School Mark Malagodi, Computer Services, Burlington High School Paul Virgin, Coordinator of Food Services, Burlington High School Nancy Spicer, Biochemist, Sepracor, Inc. Martin Isaks, Chemistry Faculty, University of Massachusetts Lowell James Hall, Director of Freshman Laboratories, University of Massachusetts Lowell

Material Assistance John Moore, Editor, Journal of Chemical Education

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Linda Fanis, Assistant Editor, Journal of Chemical Education Jamie Warren, ACS Office of Society Services for ChemMatters, ACS Terri Taylor, Manager, Office of High School Science, ACS, (ChemMatters) Robin Giroux, Assistant Managing Editor, Editing & Production, Chemical & Engineering News Marilou Cashman, Executive Secretary, NESACS

Publicity Support New England Association of Chemistry Teachers (NEACT) Massachusetts Association of Science Teachers (MAST) University of Massachusetts Lowell Northeastern Section of the American Chemical Society (NESACS) THE Nucleus (NESACS)

Abstract: Connections to Chemistry is a program designed to connect high school chemistry teachers with the numerous educational resources and programs which are available from the American Chemical Society. The Connections program has been offered every year since October 2000. This will be its 10th year having reached over 900 high school chemistry teachers from six states.

Pharmacy Career Workshop

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