KATHMANDU UNIVERSITY MEDICAL JOURNAL Hereditary Spherocytosis with Splenomegaly and Cholelithiasis in a Young Male of Western Region of Nepal - A Case Report
ABSTRACT
Corresponding Author
KEY WORDS
Cholelithiasis, hemolytic anemia, prophylaxis, splenectomy, splenomegaly
Citation
Kathmandu Univ Med J
INTRODUCTION CASE REPORTS eyes and recurrent pain in upper quadrant of abdomen for It has a wide spectrum of severity and a prevalence of This case is one of the few Case Note VOL. 13 | NO. 4 | ISSUE 52 | OCT DEC 2015
normal limits and adequate platelets with no parasites Figure 1. Splenectomy Specimen with Spelnunculi and Gall bladder with multiple small calculi. The loss of membrane surface area without a The Clinical Features manifest as anemia and hyperbilirubinemia requiring Abdominal Sonography revealed contracted gall bladder be more prominent in the newborn because hemoglobin The severity cholecystectomy with a midline abdominal incision under pigmentary gallstones can form as early as four years of rd The erythroid marrow failure can rapidly result in Laboratory investigations and findings DISCUSSION The mean The most common molecular defects are
KATHMANDU UNIVERSITY MEDICAL JOURNAL
The criteria Erythroid hyperplasia is seen in the marrow aspirate or decreased haptoglobin and the presence of gallstones on The presence Laparoscopic splenectomy decreases the length of hospital stay and has replaced A normal Vaccines for As a research Post splenectomy thrombocytosis needs (near total) splenectomy also may be useful in children Cholecystectomy is also indicated at the same Prognosis Treatment Splenectomy eliminates most of the hemolysis associated
REFERENCES 1. 3. th Archives of Hellenic Medicine 2. th 4. Kathmandu University Medical Journal 5. Pravara Med Rev