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E N O A E S S S L T A E A C R C I N S M S E E H C C TI N O CA October 2008 Vol. LXXXVII, No. 2 N • AMERI

Monthly Meeting Henry Hill Award to Dr. Michael Singer Dr. Peter Meltzer to speak at Henderson House

2008 Buyer's Guide

NESACS-GDCh German Exchange Program

National Chemistry Week Puzzle Contests 2 The Nucleus October 2008 The Northeastern Section of the American Chemical Society, Inc. Contents Office: Marilou Cashman, 23 Cottage St., Natick, MA 01360. 1-800-872-2054 Call for Applications 4 (Voice or FAX) or 508-653-6329. ______e-mail: mcash0953(at)aol.com YCC/NESACS-JCF/GDCh Exchange to Germany Any Section business may be conducted via the business office above. Monthly Meeting 5 NESACS Homepage: ______http://www.NESACS.org Presentation of the Henry Hill Award, 50-Year Members Honored, Dr. Peter David Cunningham, Webmaster ACS Hotline, Washington, D.C.: Meltzer, Organix, Inc. to speak at Henderson House on "The Establishment and 1-800-227-5558 Evolution of a Small Chemical Business in Massachusetts" Officers 2008 Connections to Chemistry 2008 6 Chair: ______Marietta Schwartz NESACS-GDCh German Exchange Program 7 Chemistry Department, UMASS-Boston ______Boston, MA 02125 By Leland Johnson 617-287-6146; marietta.schwartz(at)umb.edu Chair-Elect: Report from NERM 2008 9 Dr. E. Joseph Billo ______13 Shattuck Street By Morton Z. Hoffman Natick, MA 01760 2008 Henry Hill Award 10 508-653-3074, joseph.billo(at)verizon.net ______Immediate Past Chair: 2008 NESACS Golf Tournament 10 Mukund Chorghade 14 Carlson Circle, Natick, MA 01360 ______508-651-7809 and 308-3891 By Amy Tapper Chorghade(at)comcast.net Laboratory Health and Safety 11 Secretary: ______Michael Singer A Two-Day Short Course sponsered by the NESACS Committee on Continuing Sigma-Aldrich 3 Strathmore Rd., Natick, MA 01360 Education 508-651-8151X291; msinger(at)sial.com National Chemistry Week Events 12 Treasurer: ______James Piper National Chemistry Week Puzzle Contests 13,14 19 Mill Rd., Harvard, MA 01451 ______978-456-3155, piper28(at)attglobal.net By Chris Morse Auditor: Anthony Rosner Education Night Awards 15 Archivist: ______Myron S. Simon Annual Nucleus Buyers Guide 16 20 Somerset Rd. ______Newton, MA 02465; 617-332-5273 Cover: Romysimon(at)mindspring.com October speaker, Dr. Peter Meltzer, President and Co-Founder of Trustees: Organix Inc., Woburn, MA. (Photo courtesy of Dr. Meltzer) Joseph A. Lima, Esther A. H. Hopkins, Deadlines: Michael E. Strem December 2008 Issue: October 13, 2008 Councilors Alternate Councilors January 2009 Issue: November 10, 2008 Term Ends 12/31/2008 Doris I. Lewis Patrick M. Gordon Morton Z. Hoffman Michael P. Filosa Christine Jaworek-Lopes Lawrence Scott Mary Burgess Liming Shao Donald O. Rickter S.B. Rajur Term Ends 12/31/2009 The Nucleus is published monthly, except June and August by the Northeastern Section of the American Catherine Costello Julia H.Miwa Chemical Society, Inc. Forms close for advertising on the 1st of the month of the preceding issue. Text Patricia Mabrouk Alfred Viola Michaeline F. Chen Jerry P. Jasinski must be received by the editor six weeks before the date of issue. Dorothy J. Phillips Eva B. Binnun Editor: Michael P. Filosa, Ph.D., ZINK Imaging, Inc., 16 Crosby Drive, Building 4G, Amy Tapper Barney Grubbs Bedford, MA 01730 Email: Michael.filosa(at)zink.com; Tel: 508-843-9070 Term Ends 12/31/2010 Associate Editors: Myron S. Simon, 20 Somerset Rd., W. Newton, MA 02465, Tel: 617-332-5273 Thomas R. Gilbert Timothy B. Frigo Sheila E Rodman, Konarka Techologies Inc., 116 John St. Suite 12, Lowell, MA Pamela Nagafuji Mark Froimowitz 01852 email:srodman(at)konarka.com tel 978-569-1414 Robert Lichter David Cunningham Michael Singer Erik Rozners Board of Publications: Mary Mahaney (Chair), David Cunningham, Vivian K. Walworth Business Manager: Karen Piper, 19 Mill Rd., Harvard, MA 01451, Tel: 978-456-8622 All Chairs of standing Advertising Manager: Vincent J. Gale, P.O. Box 1150, Marshfield, MA 02050, Committees, the editor Tel: 781-837-0424; FAX: 781-837-1453 of THE NUCLEUS, and Contributing Editors: Morton Hoffman, Feature Editor; Dennis Sardella, Book Reviews the Trustees of Section Calendar Coordinator: Sheila Rodman, email: srodman(at)konarka.com Funds are members of the Photographers: Morton Z. Hoffman and James Phillips Board of Directors. Any Councilor of the American Chemical Society Proofreaders: Donald O. Rickter, Myron S. Simon, Vivian K. Walworth, E. Joseph Billo residing within the section area is an ex officio Webmaster: David Cunningham, webmaster(at)nesacs.org member of the Board of Directors. Copyright 2008, Northeastern Section of the American Chemical Society, Inc. The Nucleus October 2008 3 cultural institutions in the Essen-Mül- Call for heim-Düsseldorf area, and will include Corporate Patrons ($2000+) the JCF student chemistry research Abbott Bioresearch Applications conference (Frühjahrssymposium) in Genzyme Essen on Thursday-Saturday, March Lyophilization Service of New England 12-14, which will provide the opportu- Merck YCC/NESACS–JCF/GDCh nity for the participants to engage in National ACS Exchange to Germany extensive networking with German and Novartis March 8–15, 2009 other European students and to take Pfizer part in discussions focused on careers, Schering Corporation The Younger Chemists Committee education, and international opportuni- Sepracor (YCC) of the Northeastern Section and ties. Each student representative from Serono Reproductive Institute the NESACS Education Committee NESACS will be expected to make a Vertex Pharmaceuticals invite applications from undergraduate poster or oral presentation on his/her Wyeth Pharmaceuticals and graduate students of chemistry, research at the Frühjahrssymposium , and chemical engineering Patrons ($1000-$1999) and upon return at the Northeast Stu- at colleges and universities within the Astra-Zeneca R&D Boston dent Chemistry Research Conference Section to spend a week in Germany as Broad Institute (NSCRC) on Saturday, April 25. Air the guests of the Jungchemikerforum Creagen Biosciences tickets will be provided by NESACS; (Young Chemists Committee; JCF) of Estate of Wallace Gleekman accommodations in Germany will be the Gesellschaft Deutscher Chemiker Irix Pharmaceuticals covered by GDCh. A working knowl- (German Chemical Society; GDCh). Millennium Pharmaceuticals edge of German, while useful, will not The exchange group will consist of up PCI Synthesis be specifically required; the language to 12 students and a number of faculty of the Frühjahrssymposium and the Shasun USA and industrial representatives. other events will be English. Sirtris Pharmaceuticals The trip to Germany will begin Application forms are available on Strem Chemicals with an overnight flight from Boston the YCC and ZINK Imaging on Saturday, March 7; return to Boston NESACS Ziopharm Oncology, Inc. will be on Sunday, March 15. The websites. The following material must visit will begin with excursions to Donors ($300-$999) be submitted electronically with the industrial, academic, scientific, and Cambridge-Major Laboratories Medicilon Inc Occidental Organix Peptech Corp Royal Society of Chemistry SAPA-NE

application form: 1) the abstract of the presentation to be made at the Früh- jahrssymposium and the NSCRC; 2) an essay on the relevance of the exchange to the student’s professional goals; 3) a letter of recommendation from the stu- dent’s research supervisor; 4) approval from the supervisor and the chair of the department of the student’s absence from classes, the research laboratory, and other responsibilities. In addition, finalists will be interviewed by mem- bers of the Organizing Committee. For more information, contact Dr. Michael Strem, Chair of the Organizing Committee, at . Deadline for electronic receipt of applications: November 5, 2008, at N 5:00 p.m. 4 The Nucleus October 2008 Monthly Meeting Biography Dr. Peter Meltzer is the President and The 890th Meeting of the Northeastern Section of the American Co-founder of Organix Inc. of Woburn, Massachusetts. He is a native of South Chemical Society Africa and received his Bachelor of Henry Hill Award, Presentation and Recognition of 50-year members Science and Ph.D. degrees from the Wednesday, October 15, 2008 University of Witwatersrand in Johan- nesburg, South Africa. Upon comple- Northeastern University – Henderson House tion of his doctoral studies he came to 99 Westcliff Road, Weston, MA 02493 (781-235-8517) the Massachusetts Institute of Technol- 4:30 pm Board Meeting ogy as a Post-Doctoral Fellow. After a year at MIT he spent five years as a 5:30 pm Social Hour group leader and senior chemist at the 6:15 pm Dinner Sheehan Insitute (SISA). In 1983 he 7:15 pm Presentation of 50-Year Members became a Vice-President at H. G. Pars Pharmaceutical Laboratories until he 7:30 pm Award Meeting, Dr Marietta Schwartz, NESACS Chair, Presiding left H.G. Pars to found Organix in Henry A. Hill Award for Outstanding Service to the Northeastern 1986. From 1981-1983 Dr. Meltzer Section to Michael Singer was an Associate Editor of the Nucleus Evening Lecture: Dr Peter Meltzer, President, Organix, Inc., and from 1984-1985 he was Chair of Woburn, MA the Medicinal Chemistry Group of The Establishment and Evolution of a Small Chemical Business in NESACS. He has over 100 publica- Massachusetts tions in the area of organic and medici- nal chemistry and more than twenty N Dinner reservations should be made no later than noon, Wednesday October 8, US patents. 2008. Please call or fax Marilou Cashman at (800) 872-2054 or e-mail at Correction: MCash0953(at)aol.com. Reservations not cancelled at least 24 hours in advance In the September issue must be paid. Members, $30.00; Non-members, $35; Retirees, $20; Students, of The Nucleus, the article entitled, $10. “Two NESACS Members Honored at THE PUBLIC IS INVITED. NERM,” should have been credited to Directions to Henderson House: Ruth Tanner with photos provided by http://www.northeastern.edu/henderson/directions.html Martin Isaks. The Editor apologizes for From Route 9W exit off I-95: travel approx 2 miles. Shortly after the Rte 16 the error. In addition, Julianne Smist underpass, watch for Cliff Road exit ramp. Merge onto Cliff Road, travel 1.4 (Springfield College) is currently the miles, turn left onto Westcliff Road. ¼ mile to Henderson House Associate Secretary of the Connecticut From Route 30W exit off I-95: travel approx. 1.5 miles to Oak Street on left. Valley Local Section (not chair of the Travel approx 0.8 miles on Oak St, where it crosses Glen Road and becomes Green Mountain Section as written) N and is chair of the Board of Directors of Cliff Road. Go an additional 0.2 miles, turn right onto Westcliff Road.. N the Northeast Region of ACS, Inc.

fruition and growth to recognition as ABSTRACT industry as a viable alternative, or an one of the premier CROs in organic addition, to conducting in-house design and medicinal chemistry in the US. Organix was established in 1986 with and synthesis of proprietary organic Specific hurdles that need to be over- the goal of becoming one of the first targets, it was questionable whether come by small chemical businesses will privately held chemical companies in such a company could succeed. In par- be discussed and particular challenges the US to provide synthetic organic and ticular, it was unusual, at that time, for to contract chemistry will be presented. medicinal chemistry services to indus- the pharmaceutical industry to place Models for Contract Research Organi- tries that utilize organic molecules. highly sensitive intellectual property in zations that work and those that are less The motivating factors that might the hands of a third party. Organix was successful will be discussed. A small drive a chemist to establish an inde- a pioneer in this arena, and in the ensu- business is heavily dependent upon the pendent chemical facility within a ing years many other companies founders, their specific expertise, their highly regulated and complex business evolved to provide similar services. personal goals, ambitions and their environment are diverse. In the days This presentation will describe the personalities. The impact of these traits upon a successful chemical enterprise before Contract Research Chemistry establishment of a small chemical com- N was accepted by the pharmaceutical pany and the evolution of an idea to will be presented.

The Nucleus October 2008 5 Northeastern Section of the American Chemical Society CONNECTIONS TO CHEMISTRY 2008 The Northeastern Section of the American Chemical Society (NESACS) and the Education Committee of the Northeastern Section invite high school chemistry teachers to a program at Burlington High School (Burling- ton, MA) on Thursday, October 16th, 3:30 – 8:00 PM. This program will help connect high school teachers with the numerous education resources that are available from the American Chemical Society. Four simultane- ous hands-on workshops will illustrate these resources: • Prescribing Success for the Future with Nicole Clark, Intensive Care Clinical Pharmacist, Hallmark Health System. This workshop demonstrates activities and shares the curricular connections in chem- istry (and math) that pave the road to becoming a pharmacist, a career that links the chemical and health sciences in a world of miracle drugs. Participants will practice hands-on lab demonstrations and activi- ties to experience the career chemistry and math connections with which a pharmacist engages on a daily basis. (Workshop A) • The Real CSI Lab with Bill Hebard, Chemist, Massachusetts State Crime Laboratory. Devise an applied chemistry approach through incorporating forensics into the chemistry curriculum. Examine the basic principles of science used in the analysis of forensic evidence: the physics of blood pattern analy- sis, the chemistry of forensic toxicology and the biology of biological fluid identification. Try your hand at forensic techniques. Solve the crime! (Workshop B) • “Play Ball!” with Patrick Drane, Mechanical Engineer and Assistant Director, Baseball Research Cen- ter, University of Massachusetts Lowell. A program on the National Chemistry Week theme, Having a Ball with Chemist. Experiment with baseballs, superballs and various types of bats. High speed videos will show how the collisions occur; the chemistry of the materials in these balls and bats will explain why these balls bounce and travel.(Workshop C) • Let Your Fingers Do the Walking with Liana Lamont, Assistant Editor, Journal of Chemical Educa- tion, University of Wisconsin-Madison. A computer-based workshop to offer you a hands-on look at the extensive resources available at the ChemEd Nation Science Digital Library. The collection includes articles from the Journal of Chemical Education, the Chemistry Comes Alive demonstration videos, and the JCE Classroom Activities. (Workshop D) Program 3:30 – 4:00 Registration and Refreshments 4:00 – 4:25 Welcome and Overview 4:30 – 6:10 Four Simultaneous 50-Minute Workshops Presented in Each Session: Session I: 4:25 – 5:15 Workshops A & B & C & D Session II: 5:20 – 6:10 Workshops A & B & C & D 6:15 – 8:00 Dinner and Address Address: …And Now For Something Completely Different Thomas H. Lane, President-Elect, American Chemical Society Director, Global Science and Technology Outreach at Dow Corning Corporation

The deadline for registration is Friday, October10th. The registration fee is $18.00 and is non-refundable after October 8th. Workshop and program-related materials, dinner, a one-year subscription to ChemMatters, and a certificate for three hours of Professional Development will be provided to all workshop participants. The detailed program and registration form can be obtained from the NESACS Web site under Connections to Chemistry 2008. For additional information, contact Dr. Ruth Tanner, Chair, Education Committee, NESACS: 978/934-3662 or [email protected]

6 The Nucleus October 2008 NESACS–GDCh German Exchange Program Benefits to Career Decisions, Professional and Social Networking This account was submitted by current Chair, Leland (Lee) Johnson ([email protected], Novartis-NIBR) In the past few months, I have asked Meeting. The nicely organized pro- gation of American graduate students participants on both sides of the gram allowed us to attend the superb from the NESACS during the Atlantic to pass along their experiences conference program amongst thou- exchange program 2008 to the 10th with the German Exchange Program. sands of fellow chemists, and to visit Fruehjahrssymposium at my university When the Steering Committee for the Novartis and Harvard University in in Rostock, Germany.” German Exchange was formed, Cambridge and to enjoy a trip to Cape “In all, it has been a great pleasure Michael Strem (Strem Chemicals, Inc.) Cod in an intimate group of fewer than for me to experience this intercultural had certain expectations for the pro- twenty-five.” exchange to Boston and back in Ros- gram. When I asked, he said that the Hanns Martin continued: “In tock. Just over a year after coming to “expectations were built around the addition to the interesting program, we Boston, I have submitted my Ph.D. the- internationalization of our [chemistry] were able to develop contacts with a sis and have planned my future career. profession that had been going on for a group of graduate students from the In this regard I decided to perform a while and…was not going to decrease. Boston area. With a lot of intense and career change into a very communica- The program would [provide] the stu- inspiring discussions, I made a lot of tive, intercultural and challenging dents an opportunity to present their new friends at Boston. Subsequent to environment. After successful comple- work to an international audience, as the exchange program, I did an intra- tion of my job search, I decided to start well as to immerse themselves both doctoral research stint for several in January as a consultant with a lead- professionally and socially, albeit for a months in Cambridge and was able to ing global management consulting short time, in a different culture. In meet YCC members during that time. firm. I am looking forward to support- case they wanted to avail themselves After my return to Germany, it has ing international project teams in order of post-graduate opportunities in for- been a great honor to welcome a dele- continued on page 8 eign countries, this experience, and the contacts made, could be of some help.” Planning for the ninth exchange between NESACS/NSYCC and the GDCh/JCF, it seemed appropriate to check with several participants in order to discover the effects that the program has had on their individual (and joint) career choices. As an undergraduate or graduate student in chemistry, one is very likely to find at least one of these outcomes quite appealing. Hanns Martin Kaiser (University of Rostock), a primary organizer of the Rostock-based 2008 exchange shared his thoughts, beginning with his recol- lections from his exchange to Boston last year, and continuing to the present. “In August 2007, I had the great oppor- tunity to take part in the Exchange Pro- gram of the Northeastern Section of the American Chemical Society and the Younger Chemist Committee of the German Chemical Society. As a mem- ber in a group of 14 German graduate students I stayed in Boston for a week- long program during the ACS National

The Nucleus October 2008 7 NESACS–GDCh important role in organizing and imple- number of contacts around Boston at ment the German exchange program different stages of their careers has Continued from page 7 goals. As a result, I was elected to the given me insight into career possibili- to tackle complex problems together position of Career Chair for the ties and been useful when contacting with colleagues from very different NSYCC for the coming year. In this different groups or people. Being backgrounds and countries, and I role and through assisting Lee Johnson involved with the YCC has also been a believe that my experiences with the with the two most recent chemistry lot of fun. Last summer, I helped plan JCF and NESACS-GDCh exchange student career fairs, I have had the for and host the German delegation’s have provided an excellent opportunity opportunity to meet representatives tour of the Boston area, which was to network and learn from the chal- from the chemical industry around near the end of their week-long visit. I lenges and successes of organizing an Boston, as well as career services have great memories of visiting a event like the Fruehjahrssymposium.I advisers affiliated with the ACS. This biotech on Cape Cod, eating lobster at am sure that I will meet some of my network will continue to grow as I a clam bake, and dancing until late in friends from Boston on a professional organize the 2009 NSCCF, and I have the night with our German hosts and basis again in the future.” the German exchange program to symposium attendees.” Alex keeps in One of the NESACS/NSYCC par- thank for my introduction to the touch with many of the exchange par- ticipants in the 2008 exchange, Lynell NSYCC and my growing network.” ticipants from 2005 in Berlin and from Skewis (Boston University), described Alex Taylor, currently a post-doc the exchange to Boston last year, and, her experiences as “an exciting and (MIT), participated in the German as he mentioned, his professional and exhausting week of chemistry, net- exchange to Berlin in the spring of personal network has expanded greatly working, and socializing. Through this 2005. He recalls his experiences in since his participation. experience, my personal network was this way. “The German exchange to Tom Grossmann (Humboldt Uni- expanded by forming friendships with Berlin was the starting point for my versity), a long-time JCF member and our German hosts and getting to know involvement with the NSYCC. exchange participant, recounts his the Boston area participants, many of Through the exchange, I have met and experiences from the German side of whom I wouldn’t have met otherwise. become acquainted with the past and the exchange. “I have been a member The primary impact the exchange had current leaders of the YCC, as well as of the Jungchemikerforum (JCF, on my professional network and career members of the exchange’s steering Younger Chemists Committee) since came as I learned more about the committee, such as Mike Strem, Ruth 2000. At that time I was undergraduate NSYCC, whose members play an Tanner, and Mort Hoffman. Having a student at the Chemistry Department of the Humboldt University in Berlin, Germany. Within the JCF I met stu- dents sharing similar interests. We organized various events bringing together young chemists from several countries. At one of these meetings, the 2005 Spring Symposium in Berlin, I got to know a group of enthusiastic and interested US students who attended the exchange program between NESACS and the German Chemical Society (GDCh). I liked the idea of a permanent exchange program between young chemists from Ger- many and the US. I was pleased to meet another group of students one year later at the Spring Symposium in Konstanz. In 2007, I had the opportu- nity to participate in this exchange pro- gram and joined a group of German students visiting Boston and attending the ACS fall meeting. The trip to Boston was a great experience. We received a very warm welcome and spent a lot of time with our friends from the US.” continued on page 23

8 The Nucleus October 2008 Report from NERM 2008 By Morton Z. Hoffman NESACS Representative to the Board of Directors, Northeast Region of the ACS, Inc. More than 600 chemists, including 225 , environmental chem- presented: undergraduate and graduate students, istry, organic synthesis, layered materi- • The Green Mountain Local Section gathered on the west coast of New Eng- als, energy, industrial chemistry and th “Salute to Excellence” Award to land for the 35 Northeast Regional innovation, inorganic chemistry, physi- Omya, Inc., for its contributions to ACS Meeting (NERM 2008) in cal chemistry, analytical chemistry, chemistry and science education and Burlington, Vermont, on June 29-July medicinal chemistry, biochemistry, outreach in the local community; 2, 2008; . modeling and computer simulation, Hosted by the Green Mountain Local and chemical education. There were • The ACS Division of Chemical Edu- Section and cosponsored by the Chem- many workshops and programs for cation Northeast Region Award for ical Institute of Canada, the meeting high school teachers, students, and Excellence in High School Teaching had “Chemistry Without Borders” as chemistry enthusiasts. Tours to IBM’s to Steve Lantos (Brookline (MA) its theme. With many other industrial, Burlington Design Center and Ben & High School) for his creative, effec- academic, and international sponsors, Jerry’s ice cream factory, and an tive, and inspiring connections to his including ten ACS divisions and the evening of standup comedy with students; Royal Society of Chemistry, the meet- chemical engineering professor Peter • The 2007 E. Ann Nalley Northeast ing offered nearly 450 oral and poster Ludovice (Georgia Tech) and profes- Region Award for Volunteer Service presentations and an exhibition with 18 sional performer Rusty DeWees (“The to the ACS to Deborah Janes and vendors and two non-profit groups. Logger”) were part of the social pro- Timothy Wilson (Eastman Kodak Among the attendees were Bruce gram. Company, Rochester, NY) for their Bursten (ACS President) and Anne The meeting ended with a confer- involvement in science education O’Brien (ACS District I Director). ence cruise and award dinner aboard outreach, and the 2008 Award to The meeting featured invited and the Spirit of Ethan Allen III on Lake Christine Jaworek-Lopes contributing speakers across a wide Champlain. The weather cooperated, (Emmanuel College, Boston, MA) range of topical symposia, including producing a glorious early summer for her untiring work as coordinator green chemistry, polymer chemistry, sunset. The following awards were continued on page 24

The Nucleus October 2008 9 2008 2008 NESACS Golf Henry A. Hill Tournament Award By Amy Tapper under par was Dave Rogers, Genzyme; The 2008 Henry A. Hill award will be Steve Trahan, Genzyme; Gary Kelley, presented to Dr. Michael Singer. The Raytheon; and Anthony Tavalone, MA Hill award is presented annually to a State Highway Department. The first- member of the Northeastern Section of place team, winning their second con- ACS for outstanding service to the sec- secutive NESACS tournament, with a tion and to the profession of chemistry. score of 12 under par was Stu Needle- Dr. Singer is currently R&D Manager man, Aptuit; Jeff Wilson, Aptuit; Jim for New Products/Special Products at Geoff Tapper, Amy Tapper, Bridge Hunter, Harry Bannister, Aptuit; and Paul Delfino, Sigma-Aldrich (Natick). Dr. Singer Mandeville- Amy and Harry, Co-Chairs Delfino Marketing. obtained his B.S. degree from the State The fourth annual NESACS golf tour- In addition to the first-, second-, and University of New York at Stony nament was held on June 25, 2008 at third-place team prizes, prizes ($50 Brook (1986), his M.S. degree from Butternut Farm golf course in Stow, Butternut Farm pro shop gift certifi- Brandeis University (1988), his Ph.D. MA (www.butternutfarm.com). It was cates) were given for the longest drive from Brandeis University (1993), and a perfect day for golf, sunny with a and closest to the pin. The longest performed post-doctoral research at moderate temperature. This year a drive was on a par 5 hole and the win- Organix Inc. (1991-1994). Dr. Singer’s total of 74 golfers participated in a ner had the longest drive off the tee professional experience also includes shotgun scramble. The scramble for- that landed in the fairway. The closest the following: Group Leader, Drug mat allows players of all levels to par- to the pin was on a par 3 hole and the Discovery Research and Development, ticipate. This annual event is a great winner was the person that landed his Sigma-Aldrich (Natick) (2001-2007); venue for networking and players or her drive closest to the pin on the Group Leader, Automated Combinato- came from as far as South Carolina green. This year the longest drive for rial Synthesis, ArQule Inc. (1996- and Wisconsin to participate. The women was won by Cassandra Celatka 2001); Senior Scientist, ArQule Inc. tournament began at 1 PM and was from Genzyme and the longest drive (1994-1996); Dr Singer has served on followed by a BBQ dinner and awards for men was won by Anthony Tavalone the Board of Directors of the Notheast- ceremony. Please visit the NESACS from the MA State Highway Depart- ern Section of ACS (NESACS) (1993- website www.nesacs.org to view pho- ment. Anthony was also the male win- present) where he has held the tos of the players. ner of closest to the pin. The female following positions: Secretary- winner of the closest to the pin contest NESACS (1998-present); Councilor- was Elyse Bourque of Genzyme. NESACS (1996-2001, 2005-present); Most importantly, we would like Alternate Councilor – NESACS (2002- to acknowledge all of the sponsors of 2004); Board of Publications (1996- this event: Lyophilization Services of 1997); Summerthing (2007-2008); and New England (LSNE), IRIX, Aptuit, with the Medicinal Chemistry Group Shasun Pharma Solutions, Cam- (MCG) (1991-2000); MCG Treasurer bridge Major Laboratories, SAFC (1992-1993), MCG Program Chair Pharma, Vertex, and PCI Synthesis. (1994); MCG Chair (1995-1996). In First-place team - Paul Delfino, Jim Bannister, Industrial contributions to the North- addition to his service in NESACS, Dr. Stu Needleman, Jeff Wilson eastern Section are what enable the Singer has also served on the ACS First, second, and third place Section to be one of the most active Joint Board-Council Committee on prizes (Butternut Farm pro shop gift Sections of the American Chemical Chemical Abstracts Service as Associ- certificates) were awarded to the teams Society. To view the products and serv- ate member (2004) and Member with the lowest overall scores ices that are available from our sponsors (2005-2007), and as ACS Local Sec- ($75/player, $50/player, and $25/player please visit the NESACS website link tion Activities Committee Associate respectively). The third-place team (http://www.nesacs.org/sponsors.html). Member (2007) and Member (2008- with a score of 9 under par was Mark We look forward to another suc- 2009). The 2008 Henry A. Hill award DaFonseca, Aptuit; Darrin Sloan, cessful tournament in 2009. Informa- will be presented at the October meet- tion will be posted on the NESACS N CombinatoRx; Mahesh Padval, Com- ing of NESACS. binatoRx and Ben Andrusaitis. The website in early Spring 2009. Please second-place team with a score of 10 continued on page 24 10 The Nucleus October 2008 Two-Day Short Course: LABORATORY HEALTH AND SAFETY Sponsored by the NESACS Committee on Continuing Education. Designed to Improve the Skills and Marketability of Practicing B.S., M.S., and Ph.D. chemists, at a registration fee about half of that charged at National ACS Meetings. DATES and TIME: Thursday, Nov. 20, 2008; 8:00 a.m. – 5:00 p.m. and Friday, Nov. 21, 2008; 8:30 a.m. – 5:00 p.m. PLACE: Room 340, Eagan Center, Northeastern University, 360 Huntington Ave., Boston, MA

Laboratory Safety has become a concern of ever increasing importance, with many laboratory operations becoming substantially altered from traditional practices due to safety considerations. Yet few chemistry practitioners have had any formal training in this area. This Short Course, which has been offered successfully at numerous professional meetings since 1985, is being made available to the Northeastern Section at a tuition fee greatly reduced from that normally charged at National and Regional Meetings.

PROGRAM AGENDA: Scope of the Problem; Accidents; Legal Aspects; OSHA Lab Standard; Fire Control; Labeling; Biological and Animal Hazards; Handling Glassware; Eye and Face Protection; Planning for Emergencies; Handling Chemical Reagents; Ventilation; Electrical Safety; Storage of Chemicals; Disposal of Chemicals, Safety Equipment Display; Needs Assessment; Employee/Student Involvement; Safety Program Planning; Questions and Answers. INSTRUCTOR: Dr. James A. Kaufman, a member of the Northeastern Section and founder and President of “The Laboratory Safety Workshop,” is widely recognized as one of the nation’s leading authorities on safety in science laboratories. The Committee on Continuing Education feels fortunate to be able to present this training program by a pre-eminent authority from this Section. PRE-REGISTRATION REQUIRED – Registration Fees: ACS Members if received before Nov. 6…..…… $550.00; if received after Nov. 6 ……$645.00 Non-ACS Members if received before Nov. 6..… $650.00; if received after Nov. 6 ……$745.00 There will be a limited number of scholarships for unemployed ACS Members on a space-available basis. Full-time Students will be admitted on a space-available basis at the following reduced fees: Graduate students registering before Nov. 6 ……..... $225.00; after Nov. 6…..$325.00 Undergraduate Students registering before Nov. 6 …$125.00; after Nov. 6…..$225.00

Parking Fee: about $15.00/day University cafeterias will be available for lunches.

For further information contact: Marilou Cashman, NESACS Office, e-mail: [email protected] phone: (508) 653-6329; or toll free: (800) 872-2054

______Short Course Registration form: Laboratory Health and Safety, Nov. 20-21, 2008

Name: ______Business Affiliation: ______

Mailing ______Telephone: ______Address (Circle: Home or Work) ______E-mail: ______

Mail with remittance to: Prof. Alfred Viola, Chair Please make checks payable to NESACS Committee on Continuing Education (Sorry, we cannot accept credit cards or NESACS purchase orders.) 23 Cottage Street Natick, MA 01760

The Nucleus October 2008 11 National Chemistry Week Events Celebrating Having a Ball with Chemistry – October 18 -25, 2008

October 18, 2008 – Museum of Science Boston • Phyllis A. Brauner Memorial Lecture by Dr. Bassam Shakhashiri Dr. Bassam Shakhashiri is a Professor of Chemistry at the University of Wisconsin-Madison and is the William T. Evjue Distinguished Chair for the Wisconsin Idea. Professor Shakhashiri has captivated audiences with his scientific demonstrations at a variety of locations including Boston’s Museum of Science, the National Academy of Sciences and the Smithsonian's National Air and Space Museum in Washington.

Taking place in Cahners Theatre (2nd floor, Blue Wing) at 1:00 pm and 4:00 pm.

* Admission to the museum is required for the 1:00 pm show. Free tickets to Dr. Shakhashiri’s show will be available on a first come, first serve basis.

* Admission to the museum is NOT required for the 4:00 pm show. Tickets are available via advance reservation. To reserve tickets, please contact Marilou Cashman either via email [email protected] (preferred) or by phone 1-800-872-2054 before October 15, 2008. Tickets will be available for pick-up in the lobby of the museum at the ACS table.

• Kicking off National Chemistry Week 2008 festivities Join us in a variety of hands-on activities related to the yearly theme. Taking place from 1:00 pm - 5:00 pm on October 18, 2008 in the lower level of the Blue Wing.

October 25, 2008 – Boston Children’s Museum From 10:30 am – 4 pm, NCW volunteers will be on-hand throughout the museum to perform demonstrations and assist in hands-on activities related to the yearly theme.

September 1 – October 15, 2008 K-12 students participate in the NCW poster competition. Visit www.nesacs.org and http://portal.acs.org/portal/acs/corg/content?_nfpb=true&_pageLabel=PP_ARTICLEMAIN&node_id=1 055&use_sec=false for more information.

October 1 – 31, 2008 Grades 1-12 may participate in the puzzle contest. See www.nesacs.org or the October 2008 issue of the Nucleus for the puzzles and contest information.

12 The Nucleus October 2008 National ChemistryNational Chemistry Week Week Puzzle ContestsPuzzle Contests by Chris Morse by Chris Morse In honor of the “Having a Ball” theme of chemistry and sports, these two puzzles contain a little of both. To qualify to enter, you must be in a grade no higher than 12th. Follow the instructions for either puzzle, and e-mail your contest entry to [email protected]. Make sure to include your name, address, school, science teacher and grade. Entries will be selected and results will be posted later. A winner for each puzzle will be randomly selected from all properly solved entries. You may enter both contests if you wish. Entries must be received by October 31, 2008.

Sports Word Square: The answer to each of the randomly-ordered clues below is a six-letter word hidden in one of the rows or columns of the grid. Cross off the letters used in those twelve answers and the letter left in each box, reading left-to-right, top-to-bottom, will spell out the answer message. 12345 6 A H LLE S 1 HD EN TO MS PY MT P A E Q EE 2 PI OI DC MD IL KD S CCU S I 3 SA OL NM UC GE RT C K L OS I 4 PH EO NL AD ET AI X E R A T E 5 KU GA RI SA MO SN B Y G H L G 6 SO FO SX IO NN GD

Different versions of this sport use glide wax or grip wax for interaction with the snow Its varieties include Shotokan and Kyokushin Protective headgear for cyclists often lined with polystyrene foam Sport played by the New England Revolution Sport that Cassius Clay won the Gold Medal for in 1960 The ball used in Jai Alai with rubber on the inside and goatskin cover The double yellow ball for this sport is made from rubber that makes it extra super slow This avian shooting target is just a saucer made of chalk and pitch This sport uses a 3-inch diameter puck made of vulcanized rubber This sport uses hollow rubber balls coated in felt This track and field object, made from metal, rubber and/or wood, is 220 mm in diameter Wooden instrument used to propel a canoe

The Nucleus October 2008 13 Puzzle Contest Continued from page 13 Element Sudoku: Below is a sudoku grid that, instead of having the numbers 1 through 9, has 9 different chemical element symbols in it. The same rules apply: there can be only one of each of the 9 elements in each 3x3 box, row, and column. The first thing you need to do is figure out which of those 9 elements is represented by each of the 28 clues below and fill them into the grid. Then, solve the element sudoku. Lastly, the final answer to the contest is the phrase spelled out along the diagonal from upper left to lower right.

1234

5 6

7 89

10 11 12 13

14

15 16 17 18

19 20 21

22 23 24

25 26 27 28

1. Element with an allotrope called ozone 2. Element named after the 1921 Nobel Laureate in Physics 3. Metallic element mined from the mineral bauxite 4. Metallic element used with cadmium in rechargeable batteries 5. Element No. 13 6. Element that is spelled with a “ph” in Britain or an “f” in the U.S. 7. Element No. 7 8. Metal used for surgical implants, golf clubs and bicycle frames 9. Element discovered by Berzelius in 1817 10. Element No. 28 11. Element named for Greek mythological giants 12. Element No. 34 13. Most abundant element in the Earth’s atmosphere 14. Metal produced by the Hall-Héroult process 15. Element that is extracted via the Frasch process 16. Most abundant metallic element in the Earth’s crust 17. Element No. 22 18. Most abundant element in the Earth’s crust 19. Element named for a Greek goddess of the moon 20. Element that is spelled with an additional “i” in Britain 21. Element that is purified by the Mond process 22. The common name for this element is brimstone 23. Element No. 99 24. Second most common element in a modern U.S. dime 25. Element No. 8 26. The liquid form of this element boils at 77 K 27. Element No. 16 28. Element named for the Greek word for rainbow

14 The Nucleus October 2008 Education Night Awards Presented at Northeastern University, Boston, Massachusetts, Thursday, May 8, 2008 HIGH SCHOOL AWARDS COLLEGE AND UNIVERSITY AWARDS FIFTIETH ANNUAL AVERY A. ASHDOWN THE PHILIP L. LEVINS MEMORIAL PRIZE HIGH SCHOOL EXAMINATION CONTEST University of Massachusetts Dartmouth First Place - The Simmons College Award ChengjunWang Yuegang Zuo, Thesis Advisor Simon H. Ye Andover HS Betty Iannuccilli 2008 UNDERGRADUATE RESEARCH SCHOLARS JAMES FLACK NORRIS Second Place Adhvait M. Shah Burlington HS Peter Nassiff And THEODORE WILLIAM RICHARDS SCHOLARS Third Place Isaac O. Bleicher Newton North HS Peter Hamel Harvard College Fourth Place (tie) Alexander Gitlin Prof. Stuart L. Schreiber, Advisor Noah Arbesfeld Lexington HS Janice Compton Molecular Regulation and Modulation of Beta Cell Identity and Function Christopher Teng Lexington HS Jeff Shorter Stonehill College Joshua R. Infantine Phillips Academy Yuko Hori Devon Heath Dr. Leon Tilley, Advisor Tully Cheng Wayland HS Jay Chandler Synthesis of 1,1,1-trifluoro-4-trimethylsilyl-2-butanone-3,3-d2: Beta- Honorable Mention - First Year deuterium Isotope Effects of Electron Deficient Gamma-Silyl Cations. Josh Leung Lexington HS Janice Compton Tufts University Kyumin Lee Lexington HS Janice Compton Derek Kong Dr. John Kyriakis, Advisor Kenneth E. Tharp Phillips Academy Brian Faulk Understanding P8 and PELP: Stress Induced Transcriptional David Storch Arlington HS John Jannetti Coregulators of Matrix Metalloprotease-9 in Heart Disease Ramanjit Singh Arlington HS John Jannetti Randy X. Li Phillips Academy David Stern Wheaton College Samuel Beal Prof. Matthew Evans, Advisor Honorable Mention - Second Year Chemical weathering in the hydrological system of the Greenland Ice Rebecca. Wang Acton-Boxborough Carol Murphree Shelf Alexander J. Woolf Newton North HS Peter Hamel NESACS UNDERGRADUATE GRANTS-IN-AID Greg Silva Acton-Boxborough Carol Murphree Lorcan McGonigle Groton School Sandra Kelly Keene State College Ian F. Tenney Commonwealth School Rebecca Jackman Kevin Robbins. Dr. Colin Abernethy, Advisor Paul O’Neil Concord-Carlisle Rebecca Lucier New Soft Scorpionate Complexes of Vanadium AULA LAUDIS SOCIETY Dartmouth College Paul Cernota Phillips Academy - Andover, MA Jeffrey Garber Dr. Robert B. Grubbs, Advisor George Goodfellow Retired - New Bedford HS (Currently at Scituate HS, RI) Amphiphilic Block Copolymer Precursors to Cobalt Polymer Hybrids Faith Hughes Barnstable HS - Hyannis, MA University of Massachusetts Dartmouth Valerie Lechtanski Hopkinton HS - Hopkinton, MA Jonathan Doran Dr. Donald Boerth, Advisor Project SEED Nucleophilic Displacement Reactions DR. PHYLLIS A BRAUNER MEMORIAL BOOK AWARD Stonehill College Mentor: Dr. Louis Liotta Sabianca Delva Randolph High School Dartmouth College Nurbaity Faris Randolph High School Jeffrey Garber Dr. Robert B. Grubbs, Advisor Amphiphilic Block Copolymer Precursors to Cobalt Polymer Hybrids

Simon Ye (Andover Chengjun Wang (Uni- (MA) High School (at versity of Massachusetts left), winner of The Sim- Dartmouth) (at left), mons College Award as receiving the Philip L. first place finisher in the Levins Memorial Prize Avery Ashdown High from Michael Hearn School Examination (Wellesley College) with Contest, congratulated Yuegang Zao, his thesis by Michael Berger (Sim- advisor (at right). mons College) (Photo (Photo by Morton Z. by Morton Z. Hoffman) Hoffman)

The Nucleus October 2008 15 Annual Nucleus Buyers Guide 2008

1. How to use this Guide. First look at the PRODUCTS & 2.This Guide is distributed to the 7,500 ACS members in SERVICES DIRECTORY, which is on page 21. Find the the greater Massachusetts area. It has been estimated that Category in which you are interested. Categories are this audience purchases $350,000,000 of products and shown in bold letters. Then, under the Category look for services each year. the specialized Product/ Service area that you want and If you wish to be in next year’s Guide or are interested in copy the companies that are shown there. other American Chemical Society advertising opportunities Then go to the Company Directory (on page 16) and please contact Vince Gale, 781-837-0424 or locate the companies that provide the Product/Services [email protected]. that interest you. Complete contact information is avail- able for each company listed in the Buyers Guide. COMPANY DIRECTORY AABSPEC Instrumentation Corp Allen Datagraph,Inc. Anresco Inc 21 Finance Dr. Val Rossiter Debby Elliott Charleene Min Danbury, CT 06810 President Vice President Marketing Director (203)830-4000 x (voice) 135 Sutton Drive 2 Industrial Way 1370 Vank Dyke Avenue (203)830-4010 (fax) Plainview, NY 11803 Salem, NH 03079 San Francisco, CA 94124 www.bedoukian.com (800)783-9380 x (voice) (603)893-1983 x (voice) (415)822-1100 x (voice) [email protected] (800)781-4934 (fax) (603)893-9042 (fax) (415)822-6615 (fax) 28 www.aabspec.com www.allendatagraph.com www.anresco.com Bio-Rad Labs, Informatics Div [email protected] [email protected] [email protected] Deborah Kernan 171 114 80B Marketing Communications Mgr Accelerated Technology Lab Alliance Technologies, LLC Arendt Associates IP Group 2 PennCtr.1500 JFK Blvd Ste800 Kim Waters Jonathan Chun, Phd Jacqueline M. Arendt,Esq. Philadelphia, PA 19192 Sr. Product Specialist Director of Technology Principal (267)322-6931 x (voice) 496 Holly Grove School Rd 1 Deer Park Drive Ste D 1740 Massachusetts Avenue (267)322-6932 (fax) West End, NC 27376 Monmouth Junction, NJ 08852 Boxborough, MA 01719-2209 www.knowitall.com (910)673-8165 x (voice) (732)355-1234 x (voice) (978)897-8400 x (voice) [email protected] (910)673-8166 (fax) (732)438-8265 (fax) (978)582-5547 (fax) 56 www.atlab.com www.alliancetechgroup.com [email protected] Bioremediation Consulting Inc. [email protected] [email protected] 59 Sam Fogel 56 23 ATS RheoSystems Vice President Acquisition Solutions American Inst. of Chemists,Inc Louise Montemurro 39 Clarendon St C. Fiot Shane Danielson Administrative Assistant Watertown, MA 02472 Marketing Manager Communicatons Manager 231 Crosswicks Road (617)923-0976 x (voice) 7610 Edgeway Drive 1620 I Street NW Bordentown, NJ 08505 (617)923-0959 (fax) Houston, TX 77055 Washington, DC 20006 (609)298-2522 x (voice) www.bcilabs.com (713)957-2644 x (voice) (202)833-1838 x (voice) (609)298-2795 (fax) [email protected] www.addms.us (202)463-8498 (fax) www.atsrheosystems.com 17 [email protected] www.theaic.org [email protected] Bodycote Testing Group-WCAS 172 [email protected] 12 Eric Lindsay Advanced Inst Inc/Spiral Bio 179B Avery Filter Co. General Manager Dianne Walters-Smith American Instrument Larry Avery 9240 Santa Fe Springs Road Marketng Communications Mgr. Marion Long Technical Director Sante Fe Springs, CA 90670 2 Technology Way Sales 99 Kinderkamack Road (562)948-2225 x (voice) Norwood, MA 02062 1023 Western Avenue Westwood, NJ 07675 (562)948-5850 (fax) (781)320-9000 x2156 (voice) Haverhill, MA 01832 (201)666-9664 x (voice) www.bodycotetesting.com (781)320-8181 (fax) (978)521-2221 x (voice) (201)666-3802 (fax) [email protected] www.aicompanies.com (978)521-8822 (fax) www.averyfilter.com 65A [email protected] www.americaninstrument.com 110 Boston Analytical 14 [email protected] Banner & Witcoff, Ltd. Robert McBride Alconox Inc. 114 Ernie Linek Operations Manager Janis Bolbrock Anamet Laboratories, Inc. Senior Partner 8 Industrial Way—#D3 Director of Special Projects Kenneth Pytlewski,PE 28 State Street, 28th Floor Salem, NH 03079 30 Glen Street Dir,Engineering & Lab Testing Boston, MA 02109-1775 (603)893-3758 x (voice) White Plains, NY 10603 26102 Eden Landing Rd. Ste. 3 (617)720-9600 x (voice) (603)893-1268 (fax) (914)948-4040 x151 (voice) Hayward, CA 94545-3811 (617)720-9601 (fax) [email protected] (914)948-4088 (fax) (510)887-8811 x (voice) www.bannerwitcoff.com 12C www.alconox.com (510)887-8427 (fax) [email protected] Branson Ultrasonics Corp [email protected] www.anameticinc.com 59 Ed Topolski 29 [email protected] Bedoukian Research Director - Commercial Products 23 Izzy Heller 41 Eagle Rd Sales Manager Danbury, CT 06813-1961

The Nucleus October 2008 16 COMPANY DIRECTORY (203)796-0532 x (voice) Cargille Laboratories [email protected] (781)938-1122 x (voice) (203)796-2240 (fax) Dorothy Schneider 12C,12D,12F,12G,12H,23,24,25, (781)938-1123 (fax) www.sonifier.com Advertising Administrator 34,50,65,65A,69,72,75,76,80,80B www.creagenbio.com [email protected] 55 Commerce Road Chrom Tech, Inc. [email protected] 16 Cedar Grove, NJ 07009 Michelle Izerson 23 Brookfield Engineering Lab Inc (973)239-6633 x (voice) Marketing Manager Dendritic Nanotechnologies,Inc Robert McGregor (973)239-6096 (fax) P.O. Box 2428 Ryan Hayes PhD Sales/Marketing Manager www.cargille.com Apple Valley, MN 55124 Director Business Development 11 Commerce Blvd [email protected] (800)822-5242 x (voice) 2625 Denison Drive Middleboro, MA 02346-1031 3,9,12,68,114,119A,144 (952)431-6345 (fax) Mount Pleasant, MI 48858 (508)946-6200 x143 (voice) Case Consulting Labs., Inc. [email protected] (989)774-6565 x (voice) (508)946-6262 (fax) Charles Anthony 41 (989)774-2322 (fax) www.brookfieldengineering.com President Chromatography Forum Del Val www.dnanotech.com [email protected] 622 Rt 10 Bill Reuter [email protected] 12 Whippany, NJ 07981 Publicity Chairman 38 Brookhaven Instruments (973)428-9666 x (voice) 14 Shoal Drive DuPont Analytical Solutions Irene Mueller (973)887-4419 (fax) Barnegat, NJ 08005 Larry Ryan Marketing Manager www.case-labs.com (609)607-9630 x (voice) Business Manager 750 Blue Point Road case-labs.com (609)607-9723 (fax) POB#80323,ExpStaBldg302, Holtsville, NY 11742-1832 80B [email protected] Rm211B (631)758-3200 x101 (voice) Castagna Consulting Group, LLC 179B Wilmington, DE 19880-0323 (631)758-3255 (fax) Michael Castagna Clark Solutions (302)695-3953 x (voice) www.bic.com Principal Don Tyler (302)695-1717 (fax) [email protected] Wall St Tower, Suite #808 10 Brent Drive [email protected] 4,6A,12B Manchester, NH 03101 Hudson, MA 01749 65A Bruker Daltonics (603)625-1912 x (voice) (978)568-3400 x (voice) Eastern Scientific Co. Darwin Asa (603)641-6493 (fax) (978)568-0060 (fax) Tom James Marketing Manager www.castagnaconsultinggroup.com www.clarksol.com General Manager 40 Manning Road [email protected] [email protected] 301 Winter Street, Unit E Billerica, MA 01821 66 138 Hanover, MA 02339 (978)663-3660 x1149 (voice) The Catalyst Group Resource Columbia Analytical Services (781)826-3456 x (voice) (978)663-5993 (fax) Jeanne Drahos Ralph Poulsen (781)826-3448 (fax) www.bdal.com Director Sales Marketing Laboratory Director www.easternsci.com [email protected] P.O. Box 680 3860 S. Palo Verde, Suite 302 [email protected] 12C,12D,14,17,18,19,24,42A,46, Spring House, PA 19477 Tucson, AZ 85714 100,110,112,114,129, 172 (215)628-4447 x (voice) (520)573-1061 x (voice) EDAX Inc. Bulbtronics, Inc. (215)628-2267 (fax) (520)573-1063 (fax) Judy O’Loughlin Barbara Kaplan [email protected] www.caslab.com Americas Sales Manager Marketing Manager 64 [email protected] 91 McKee Drive 45 Banfi Plaza CeramOptec Industries Inc. 20,21A,23,24,65A,74B,80B,90,150 Mahwah, NJ 07430 Farmingdale, NY 11735 Cheryl Smith Complete Analysis Laboratories (800)535-3329 x (voice) (631)249-2272 x (voice) 515 Shaker Road Dr. Zvi Blank (201)529-3156 (fax) (631)249-6066 (fax) East Longmeadow, MA 01028-3126 President www.edax.com www.bulbtronics.com (413)525-0600 x (voice) 1259 Route 46, Bldg. #4 [email protected] [email protected] (413)525-0611 (fax) Parsippany, NJ 07054 89 120 www.ceramoptec.com (973)335-2254 x (voice) Elemental Analysis Corp Cambrex Corporation [email protected] (973)335-0556 (fax) Mark Stauffer Ken Drew PhD 143 www.calilabs.com Marketing Manager Manager Sales & Devt,Northeast The Chem Show [email protected] 101 Venure Ct., Ste.B-1 One Meadowlands Plaza, 15th fl Clay Stevens 20,21A,23,24,69,74B,77,80,80B, Lexington, KY 40511 East Rutherford, NJ 07073 President/Show Director 81,90 (859)254-5115 x (voice) (603)882-2602 x (voice) 15 Franklin Street Consolidated Stills&Sterilizer (859)254-5150 (fax) (201)804-3070 (fax) Westport, CT 06880 George Lowe www.elementalanalysis.com www.cambrex.com (203)221-9232 x13 (voice) Vice President [email protected] [email protected] (203)221-9260 (fax) P O Box 297 80B 35A www.chemshow.com Boston, MA 02134 ESA Biosciences, Inc. Cambridge Isotope Laboratories [email protected] (617)782-6072 x (voice) John Waraska Tasha Agreste 179B (617)787-5865 (fax) Marketing Manager Marketing Specialist Chemir Analytical Services www.consteril.com 22 Alpha Road 50 Frontage Road Jodi Wiener [email protected] Chelmsford, MA 01824 Andover, MA 01810 Marketing Specialist 95 (978)250-7083 x (voice) (978)749-8000 x215 (voice) 2672 Metro Blvd. CreaGen (978)250-7087 (fax) (978)749-2768 (fax) Maryland Heights, MO 63043 Raj Rajur www.esainc.com www.isotope.com (314)291-6620 x (voice) CEO [email protected] [email protected] (314)291-6630 (fax) 23 Rainin Road 12C 13,25A,28,29,35,35A,38,39,149, www.chemir.com Woburn, MA 01801 181

The Nucleus October 2008 17 COMPANY DIRECTORY Excel for Scientists&Engineers Glas-Col HT Laboratories, Inc. www.internationalcrystal.net Joseph Billo, PhD James Jacso Albert Chong [email protected] 13 Shattuck Street Dir. Sales & Engineering COO 133 Natick, MA 01760 711 Hulman Street 9823 Pacific Heights Blvd,SteF International Equip Trading (508)653-3074 x (voice) Terre Haute, IN 47802 San Diego, CA 92121 CK [email protected] (812)235-6167 x (voice) (858)677-9432 x (voice) Marketing 179B (812)234-6975 (fax) (858)677-0240 (fax) 960 Woodlands Pkway G. Finkenbeiner Inc. [email protected] www.HT-LABS.COM Vernon Hills, IL 60061 Thomas Hession 114 19 (847)913-0777 x (voice) Vice President Glen Mills Inc. Huffman Laboratories, Inc. (847)913-0785 (fax) 33 Rumford Avenue Stanley Goldberg William Huffman www.ietltd.com Waltham, MA 02453 Marketing Manager Vice President [email protected] (781)899-3138 x (voice) 220 Delawanna Avenue 46300 Indiana Street 172 (781)647-4044 (fax) Clifton, NJ 07014 Golden, CO 80040-3-18 IQsynthesis www.finkenbeiner.com (973)777-0777 x (voice) (303)278-4455 x (voice) Todd Stark [email protected] (973)777-0070 (fax) (303)278-7012 (fax) Global Business Operations Dir 116 www.glenmills.com www.huffmanlabs.com 11810 Borman Drive Fisher Global Chemical [email protected] [email protected] St. Louis, MO 63146 Mondolfi:Peter 97 21A (800)506-9892 x (voice) Territory Manager-New England Goodfellow Corporation ICF International (314)991-2834 (fax) 1 Reagent Lane Stephen Aldersley Kevin Palaia www.iqsynthesis.com Fair Lawn, NJ 07410 Marketing Manager Principal [email protected] (617)515-6062 xLOCL (voice) 800 Lancaster Ave 33 Hayden Avenue, 3rd Floor 146 (817)549-6062 (fax) Berwyn, PA 19312-1780 Lexington, MA 02421 JASCO www.fisherchem.com (610)640-1612 x (voice) (781)767-4000 x (voice) Harriet Mills [email protected] (610)993-8065 (fax) (781)676-4005 (fax) Marketing Manager 79 [email protected] www.icfi.com 8649 Commerce Drive Flow Sciences, Inc. 38 [email protected] Easton, MD 21601 Julie Cook GOW-MAC Instrument Co. 66 (410)822-1220 x119 (voice) Marketing Coordinator Sales ICON (Isotope) Services Inc. (410)822-7526 (fax) 2025 Mercantile Dr. 277 Broadhead Rd. John Kilby www.jascoinc.com Leland, NC 28401 Bethlehem, PA 18017 Marketing Manager [email protected] (800)695-3429 x (voice) (610)954-9000 x (voice) 19 Ox Bow Lane 174 (910)763-1220 (fax) (610)954-0599 (fax) Summit, NJ 07901 www.gow-mac.com KNF Neuberger www.flowsciences.com (908)273-0449 x (voice) Richard Rauth [email protected] [email protected] (908)273-2956 (fax) 42A,43,84A,85,86,87A Manager, Mktg. Communications 107A www.iconisotopes.com 2 Black Forest Rd. Frinton Laboratories, Inc. Headwall Photonics, Inc. [email protected] Trenton, NJ 08691-1810 Dr. George Inglessis David Bannon 35 (609)890-8600 x225 (voice) Marketing Manager Sales and Marketing Impact Analytical,Div.of M.M.I (609)890-8323 (fax) P.O. Box 2428 601 River Stree Eric Hill www.knf.com/usa.htm Vineland, NJ 08362 Fitchburg, MA 014200 Marketing Development Manager [email protected] (856)722-7037 x (voice) (978)353-4100 x (voice) 1910 West St. Andrews Road 114,129,137 (978)348-1864 (fax) (856)439-1977 (fax) Midland, MI 48640-2696 Kopella Analytical Services www.frinton.com www.HeadwallPhotonics.com (989)892-5555 x (voice) [email protected] Scott Moe [email protected] (989)832-5560 (fax) President & CEO 35B 174 www.impactanalytical.com Hellma Cells 365 Boston Post Rd., Unit 247 [email protected] Sudbury, MA 01776 Front Run Organx, Inc. Daniel Fields 23 (774)232-0673 x (voice) Mallory F. Loewe, Ph.D. Director of Marketing (508)251-1423 (fax) President 80 Skyline Drive Impandex, Inc. www.gcmsanalysis.com 17 Hayward St Plainview, NY 11803 Stanley Goldberg [email protected] Ipswich, MA 01938 (516)935-0007 x (voice) Marketing Manager 146 (978)356-7133 x (voice) (516)939-0555 (fax) 220 Delawanna Avenue (978)356-7449 (fax) www.hellmausa.com Clifton, NJ 07014 Laboratory Compliance Services [email protected] [email protected] (973)777-0777 x (voice) Stephen Chace 28 93,105A,115,120A,122,133,134, (973)777-0070 (fax) Consultant & Analytical Chem Gentech Scientific, Inc. 135A,166,168,171,176 www.glenmills.com 645 N. Central [email protected] Marketing Manager High-Purity Standards Winchendon, MA 01475 104 (978)235-2075 x (voice) 23 Mill Street Darlene Yon [email protected] Arcade, NY 14009 Customer Service Manager International Crystal Labs 80B (585)492-1068 x (voice) P O Box 41727 Robert Herpst (585)492-0383 (fax) Charleston, SC 29423 Managing Director Mallinckrodt Baker, Inc. www.GenTechScientific.com (843)767-7900 x (voice) 11 Erie Street Patrick Riley [email protected] (843)767-7908 (fax) Garfield, NJ 07026 Global Marketing Mrg.Lab Prod 42A [email protected] (973)478-8944 x (voice) 222 Red School Lane 39 (973)478-4201 (fax) Phillipsburg, NJ 08865

18 The Nucleus October 2008 COMPANY DIRECTORY (800)582-2537 x (voice) Nacalai USA Inc. OLIS, Inc. www.pion-inc.com (908)859-6905 (fax) Ono Toshi Carrie Sommers [email protected] www.mallabaker.com Vice President Assistant to VP 12C,12D,12G,18,19,23,60,65,74B, [email protected] 6640 Lusk Blvd. Ste: A200 130 Conway Drive Suites A & B 76,77,81,176,179B 38 San Diego, CA 92121 Bogart, GA 30622-1724 Polymer Processing Institute Mass Vac, Inc. (858)404-0403 x (voice) (706)353-6547 x (voice) Theodore Davidson David Rolph (858)404-0408 (fax) (706)353-1972 (fax) Manager of Special Projects Sales Manager www.nacalaiusa.com www.olisweb.com 218 Central,GITC Bldg.Ste 3901 PO Box 359 [email protected] [email protected] Newark, NJ 07102 North Billerica, MA 01862 44 167 (973)642-4582 x (voice) (978)667-2393 x (voice) New Era Enterprises, Inc. On Assignment Lab Support (973)642-4594 (fax) (978)671-0014 (fax) Robert Svihia Daniel McGowan www.polymers-ppi.org www.massvac.com Product Manager Senior Account Executive [email protected] [email protected] P.O. Box 747 One New Eng Exec Park,Ste#101 75 137 Vineland, NJ 08362-0747 Burlington, MA 01803 Polymer Standards Serv,USA Inc Matech Associates (856)799-2005 x (voice) (781)229-2505 x (voice) Michael Gray Dr. B. Chowdhury (856)697-8727 (fax) (781)229-1902 (fax) 43 Jefferson Blvd. Ste.3 Materials Consultant www.newera-spectro.com www.onassignment.com Warwick, RI 02888 407 WLE [email protected] [email protected] (401)780-8884 x (voice) Lake Ariel, PA 18436 133 57A (401)780-8824 (fax) (570)689-4752 x (voice) New Jersey Inst. of Technology Organix Inc. www.pssgpcshop.com (570)689-4752 (fax) Larisa Krishtopa Howard Sard [email protected] www.matechlab.com Laboratory Director Vice President 4,9,12,15,23,42,46,56,65A,75, [email protected] 138 Warren Street 240 Salem Street 80B,179B 80B Newark, NJ 07102 Woburn, MA 01801 PolyOrg Inc. (973)596-5858 x (voice) (781)932-4142 x (voice) Dr. Saroj Roy Matreya LLC (973)642-7170 (fax) Gary Walker (781)933-6695 (fax) President [email protected] www.organixinc.com VP of Manufacturing 12H 10 Powers Street 168 tressler Street [email protected] Leominster, MA 01453 Pleasant Gap, PA 16823 Northeastern University 12C,12D,12H,28,35A,65,146 (978)466-7978 x (voice) (800)342-3595 x (voice) Robert Hanson, PhD Organomed Corporation (978)466-8084 (fax) ( ) - (fax) Dept Chem & Chemical Bio James Jacob www.polyorginc.com www.matreya.com 360 Huntington Ave,Hurtig Hall President [email protected] [email protected] Boston, MA 02115 11 Grandview St., Unit 8 27A,28,34,35A,35B,146 38 (617)373-8720 xHOME (voice) Coventry, RI 02816 (617)373-8795 (fax) Prime Organics Metabolic Solutions, Inc. (401)826-7240 x (voice) Jonathan Kremsky [email protected] (401)826-7315 (fax) Martin Baker 179B President Vice President www.organomed.com 10 Powers Street 460 Amherst Street Northern Analytical Laboratory [email protected] Leominster, MA 01851 Nashua, NH 03063 Dick Guidoboni 28 (978)466-7978 x19 (voice) (603)598-6960 x (voice) President PCI Synthesis (978)466-8084 (fax) (603)598-6973 (fax) 13 Delta Drive Melissa Huang www.primeorg.com www.metsol.com Londonderry, NH 03053 Manager New Business Devt [email protected] [email protected] (603)434-8400 x (voice) 9 Opportunity Way 146 12D (603)434-8500 (fax) Newburyport, MA 01950 www.northernanalytical.com Quartz Plus Inc. Micron Inc. (508)533-5012 x (voice) Joseph Thomas [email protected] (508)533-5012 (fax) James Ficca Jr. 24 Vice President President [email protected] 27 Westview Road Numare Spectralab Inc. 146 3815 Lancaster Pike Lawrence Byrnes Brookline, NH 03033 Wilmington, DE 19805 Lab Mgr. & Research Director Photonics Spectra/Laurin Publ. (603)673-5690 x (voice) (302)998-1184 x (voice) 3551 Winding Road Nancy Lamontagne (603)673-5766 (fax) (302)998-1836 (fax) Kintnersville, PA 18930-9543 2 South St. Berkshire Common www.quartzplus.com www.micronanalytical.com (610)346-8660 x (voice) PO Box 4949 [email protected] [email protected] (610)346-7571 (fax) Pittsfield, MA 01202 116 23 www.eclipse.net/~numare/ (413)499-0514 x (voice) Restek Corporation Molecular Knowledge Systems [email protected] (413)442-3180 (fax) Mark Lawrence Dr. Kevin Joback 12H www.Photonics.com New England Tech/Sales Rep. Marketing Manager [email protected] 110 Benner Circle NuMega Resonance Labs. 179 P.O. Box 10755 Frances Shen Bellefonte, PA 16823 Bedford, NH 03110-0755 Vice President pION Inc. (800)356-1688 x2318 (voice) (603)472-5315 x (voice) 11526 Sorrento Valley Rd,SteB2 Rebecca Selfridge (814)353-1309 (fax) (603)472-5359 (fax) San Diego, CA 92121 Administrative Asst. www.restek.com www.molknow.com (858)793-6057 x (voice) 5 Constitution Way [email protected] [email protected] (858)793-2607 (fax) Woburn, MA 01801-1024 11,19B,41,42,42A,44 56 [email protected] (781)935-8939 x (voice) 12H (781)935-8938 (fax)

The Nucleus October 2008 19 COMPANY DIRECTORY Richman Chemical, Inc. [email protected] [email protected] Bedford, MA 01730 768 N. Bethelham Pike 28 23 (781)275-3330 x (voice) Lower Gwynedd, PA 19002 Shimadzu Scientific Instrument Strem Chemicals, Inc. (781)271-1137 (fax) (215)628-2946 x (voice) Rob Buco Peter Chu, PhD www.toxikon.com (215)628-4262 (fax) Mass Spectrometry Specialist Sales & Marketing Manager [email protected] www.richmanchemical.com 126 Longwater Dr. 7 Mulliken Way Dexter Inds. Pk 13A [email protected] Norwell, MA 02061 Newburyport, MA 01950-4098 Transene Co. Inc. 38 (800)396-4943 x (voice) (978)499-1600 x (voice) Christoper Christuk Robertson Microlit Labs (781)878-7212 (fax) (978)465-3104 (fax) Manager Rudolf Oeckinghaus Phd www.ssi.shimadzu.com www.strem.com 10 Electronics Avenue President [email protected] [email protected] Danvers, MA 01923 PO Box 927, 29 Sampson Ave. 114 27 (978)777-7860 x (voice) Madison, NJ 07940 Siemens Water Technolgies Taylor Technologies Inc. (978)739-5640 (fax) (973)966-6668 x201 (voice) Julie Mulligan Customer Service Rep. 33 (973)966-0136 (fax) Marketing Manager Customer Service Dept. TRI/Princeton www.robertson-microlit.com 10 Technology Dr. 31 Loveton Circle Eleanor Lehman [email protected] Lowell, MA 01851 Sparks, MD 21152 Marketing Manager 20 (800)875-5000 x (voice) (800)837-8548 x (voice) 601 Prospect Ave., PO Box 625 Rudolph Instruments (978)453-5821 (fax) (410)771-4291 (fax) Princeton, NJ 08540 Patrick O’Keefe www.usfilter.com www.taylortechnologies.com (609)430-4820 x (voice) Vice President [email protected] customerservice@taylortechnologies. (609)683-7149 (fax) DenvilleTechPk, 400 Morris Ave 90 com www.triprinceton.org Denville, NJ 07834 Smiths Detection-Danbury 12A [email protected] (888)478-3657 x (voice) Dana Knox-Gower TCI America 65 (973)983-6290 (fax) Marketing Manager Michelle Anselmo U.S. Services, Inc. www.rudolphinstruments.com 21 Commerce Drive Reagent Sales Manager John Kilby [email protected] Danbury, CT 06810 9211 N. Harborgate Street Marketing Manager 8,9,12C,24,148 (203)207-9700 x (voice) Portland, OR 97203 19 Ox Bow Lane Schwarzkopf Microanalytical dana.knox- (503)283-1681 x (voice) Summit, NJ 07901 Florence Wohl [email protected] (503)283-1987 (fax) (908)273-0440 x (voice) Executive V.P. 156 www.tciamerica.com (908)273-2956 (fax) 5619 37th Ave. SOCMA [email protected] www.iconisotopes.com Woodside, NY 11377 Larry Bafundo 13,28,35A,35B,37,38,44 [email protected] (718)429-6248 x (voice) Business Development Manager Techne Inc. 38 (718)429-5785 (fax) 1850 M. Street, NW, Suite 700 Christian Dyott United Electric Controls Co. [email protected] Washington, DC 20036 Sales & Marketing Dept. K. Kotwal [email protected] (202)721-4156 x (voice) 3 Terri Lane Suite #10 Marketing Comm Specialist 20,21A,23 (202)296-8120 (fax) Burlington, NJ 08016 180 Dexter Ave. Scientific Asset Management, L www.socma.com (609)589-2561 x (voice) Watertown, MA 02472 Christopher McManemin [email protected] (609)589-2571 (fax) (617)926-1000 x (voice) Marketing Manager 60 www.techneusa.com (617)926-4354 (fax) 99 Lurline Drive Sorbent Technologies, Inc. [email protected] www.ueonline.com Basking Ridge, NJ 07920 Danielle Downs Trott 12G [email protected] (908)604-1417 x (voice) Public Relations Technology Exchange Corp. 128 (908)604-1417 (fax) 2377 John Glenn Drive, Ste#106 Stan Kovall ValQual Intl. www.gotosam.com Atlanta, GA 30341 Director of Marketing Shib Mookherjea PhD [email protected] (678)222-0288 x (voice) 104 Anaway St. 2nd Flr East Senior Director 114 [email protected] Fall River, MA 02721 3989 Pemberly Pines Circle Scientific Bindery 42A (508)675-4977 x (voice) Saint Cloud, FL 34769 Nancy McDonald Spectrix (508)675-3272 (fax) (201)615-6346 x (voice) Administrative Asst. Marie D’Andrea [email protected] (407)498-2027 (fax) 2612-18 W. Nelson Owner 164 www.valqualintl.com Chicago, IL 60618 P.O. Box 234 Thermo Fisher Scientific [email protected] (773)267-1129 x (voice) Middleton, CT 06457 Boyd:Denise 63,74B,80B,151,179B (773)267-1218 (fax) (860)346-5582 x (voice) Marketing Communications Mgr. VHG Labs www.scientificbindery88yrs.com (860)343-9350 (fax) 25 Nimble Hill Road Michael Travers [email protected] www.spectrixservices.com Newington, NH 03801 VP Marketing & Sales 158,159,160,161,162, [email protected] (603)436-9444 x (voice) 276 Abby Road Seres Laboratories Inc. 12D (603)436-8411 (fax) Manchester, NH 03103 Mark Frishberg, PhD Strategic Diagnostics www.thermo.com.tc (603)622-7660 x (voice) President [email protected] (603)622-5180 (fax) Boyle:Sheila 96 3331-B Industrial Drive Regional Sales Representative www.vhglabs.com Santa Rosa, CA 95403 111 Pencader Drive Toxikon Corporation [email protected] (707)526-4526 x (voice) Newark, DE 19702 Fred Deckert 24 (707)523-4707 (fax) (302)753-4017 x (voice) Dir Analytical & Toxicology www.sereslabs.com sdix.xom 15 Wiggins Avenue

20 The Nucleus October 2008 COMPANY DIRECTORY Waters Corporation 34 Maple Street (856)697-0536 (fax) 12C,12D,12E,12H,18,19,20,65, Eaton Steven Milford, MA 01757 www.wilmad.com 74B,77 Marketing Manager (800)252-4752 x (voice) [email protected] YourEncore, Inc. 34 Maple Street (508)634-3305 (fax) 116 Herb Young Milford, MA 01757 www.waters.com XenoBiotic Laboratories, Inc. Network Assest Specialist (508)482-2950 x (voice) [email protected] Neil J. Lewis PhD 10925 reed Harman Hwy, Ste#114 (508)482-2674 (fax) 44,46,172 Vice Pres Pharmceutical Div Cincinnati, OH 45242 www.waters.com Wilmad/Lab Glass 107 Morgan Lane (513)794-9777 x (voice) [email protected] Glenda Marinelli Plainsboro, NJ 08536 (913)794-9781 (fax) 12C Marketing Support (609)799-2295 x215 (voice) www.yourencore.com Waters Corporation P.O. Box 688, 1002 Harding Hwy (609)799-7497 (fax) [email protected] Joanne Fortunato Buena, NJ 08310-0688 www.xbl.com 77 Executive Sales Representative (856)697-3000 x (voice) [email protected]

PRODUCTS & SERVICES DIRECTORY ANALYTICAL Organix Inc. 19-Bioanalytical service 27A-Chiral & custom EQUIPMENT pION Inc. LC/MS chemicals Spectrix Bruker Daltonics PolyOrg Inc. 3-Densitometers XenoBiotic Laboratories, Inc. HT Laboratories, Inc. Cargille Laboratories 28-Custom synthesis 12E-Radio chromatography pION Inc. Bedoukian Research 4-Molecular weight analyzers XenoBiotic Laboratories, Inc. XenoBiotic Laboratories, Inc. Cambridge Isotope Laboratories Brookhaven Instruments 12F-TLC 20-Certificates of analysis Front Run Organx, Inc. Polymer Standards Serv,USA Inc Chemir Analytical Services Columbia Analytical Services Organix Inc. 6A-Particle size 12G-UV-Visible Spectroscopy Complete Analysis Laboratories Organomed Corporation Brookhaven Instruments Chemir Analytical Services Robertson Microlit Labs PolyOrg Inc. 8-Polarimeters pION Inc. Schwarzkopf Microanalytical Seres Laboratories Inc. Rudolph Instruments Techne Inc. XenoBiotic Laboratories, Inc. TCI America 9-Refractometers 12H-NMR Spectroscopy 21A-Elemental Microanalysis 29-Detergents Cargille Laboratories Chemir Analytical Services Columbia Analytical Services Alconox Inc. Polymer Standards Serv,USA Inc New Jersey Inst. of Technology Complete Analysis Laboratories Cambridge Isotope Laboratories Rudolph Instruments Numare Spectralab Inc. Huffman Laboratories, Inc. 33-Inorganic chemicals Schwarzkopf Microanalytical 11-Syringes NuMega Resonance Labs. Transene Co. Inc. Restek Corporation Organix Inc. 23-Testing laboratory 34-Intermediates XenoBiotic Laboratories, Inc. Alliance Technologies, LLC 12-Viscometers Chemir Analytical Services Anamet Laboratories, Inc. PolyOrg Inc. ATS RheoSystems BIOTECHNOLOGY Chemir Analytical Services Brookfield Engineering Lab Inc Columbia Analytical Services 35-Isotopes Cargille Laboratories 13-Biochemicals Complete Analysis Laboratories Cambridge Isotope Laboratories Polymer Standards Serv,USA Inc Cambridge Isotope Laboratories CreaGen ICON (Isotope) Services Inc. 12A-Water test kits TCI America Impact Analytical,Div.of M.M.I 35B-Organic Compounds Taylor Technologies Inc. 13A-Biology/toxicology Micron Inc. Frinton Laboratories, Inc. 12B-Weighing balances & analysis pION Inc. PolyOrg Inc. scales Toxikon Corporation Polymer Standards Serv,USA Inc TCI America Brookhaven Instruments 14-Biomedical equipment Schwarzkopf Microanalytical 35A-Pharmaceutical Advanced Inst Inc/Spiral Bio Strategic Diagnostics intermediates ANALYTICAL Bruker Daltonics 24-Trace element analysis Cambrex Corporation SERVICES 15-Biomedical polymers Bruker Daltonics Cambridge Isotope Laboratories Polymer Standards Serv,USA Inc Chemir Analytical Services Organix Inc. 12C-HPLC Columbia Analytical Services PolyOrg Inc. Boston Analytical 16-Cell disruption Complete Analysis Laboratories TCI America Bruker Daltonics Branson Ultrasonics Corp Northern Analytical Laboratory Chemir Analytical Services 37-Reagents 17-Microbiology Rudolph Instruments TCI America ESA Biosciences, Inc. Bioremediation Consulting Inc. VHG Labs Organix Inc. Bruker Daltonics 38-Research Chemicals pION Inc. 25-Thermal analysis Cambridge Isotope Laboratories Rudolph Instruments CHEMICAL Chemir Analytical Services Dendritic Nanotechnologies,Inc Waters Corporation ANALYSIS Goodfellow Corporation XenoBiotic Laboratories, Inc. CHEMICALS Mallinckrodt Baker, Inc. 18-Bio-analyses by HPLC 25A-Amino acids Matreya LLC 12D-Mass Spectrometry Bruker Daltonics Bruker Daltonics Cambridge Isotope Laboratories Richman Chemical, Inc. pION Inc. 27-Chiral catalysts TCI America Chemir Analytical Services XenoBiotic Laboratories, Inc. Metabolic Solutions, Inc. Strem Chemicals, Inc. U.S. Services, Inc.

The Nucleus October 2008 21 PRODUCTS & SERVICES DIRECTORY 39-Solutions, standard TRI/Princeton 87A-Thermal conductivity 128-Process controls Cambridge Isotope Laboratories XenoBiotic Laboratories, Inc. GOW-MAC Instrument Co. United Electric Controls Co. High-Purity Standards 65A-Contract testing laboratory 129-Pumps Bodycote Testing Group-WCAS ELECTRON Eastern Scientific Co. CHROMATOGRAPHY Chemir Analytical Services MICROSCOPY KNF Neuberger 41-Accessories & supplies Columbia Analytical Services 89-Electron Microscopy 133-Spectrophotometer cells Chrom Tech, Inc. DuPont Analytical Solutions EDAX Inc. Hellma Cells Restek Corporation Polymer Standards Serv,USA Inc International Crystal Labs 42-Columns, prepacked 66-Engineering ENVIRONMENTAL New Era Enterprises, Inc. Polymer Standards Serv,USA Inc Castagna Consulting Group, LLC ANALYSIS 134-Tungsten halogen lamps Restek Corporation ICF International 90-Environmental analysis Hellma Cells 42A-Chromatography 68-Forensic analyses Columbia Analytical Services 135A-UV-visible lamps Cargille Laboratories Bruker Daltonics Complete Analysis Laboratories Hellma Cells Gentech Scientific, Inc. 69-Infrared analyses Siemens Water Technolgies GOW-MAC Instrument Co. 137-Vacuum equipment Chemir Analytical Services KNF Neuberger Restek Corporation Complete Analysis Laboratories GENERAL Sorbent Technologies, Inc. Mass Vac, Inc. 72-NMR analysis EQUIPMENT 138-Valves 43-Gas Chemir Analytical Services GOW-MAC Instrument Co. 93-AA lamps Clark Solutions 74B-Pharmaceutical analysis Hellma Cells 44-HPLC columns Columbia Analytical Services LASER SYSTEMS Nacalai USA Inc. Complete Analysis Laboratories 95-Autoclaves Restek Corporation Consolidated Stills&Sterilizer 143-Laser systems pION Inc. CeramOptec Industries Inc. TCI America ValQual Intl. 96-Baths Waters Corporation XenoBiotic Laboratories, Inc. Thermo Fisher Scientific MICROSCOPES & 46-Liquid 75-Polymers 97-Blenders, mixers, stirrers SERVICES Bruker Daltonics Chemir Analytical Services Glen Mills Inc. Polymer Standards Serv,USA Inc Polymer Processing Institute 100-Centrifuges 144-Microscope accessories Waters Corporation Polymer Standards Serv,USA Inc Eastern Scientific Co. Cargille Laboratories COATINGS 76-Product formulation 104-Crushers & grinders ORGANIC Chemir Analytical Services Impandex, Inc. 50-Contract research pION Inc. SYNTHESIS Chemir Analytical Services 105A-Deuterium Lamps 77-R & D Hellma Cells 146-Organic synthesis Complete Analysis Laboratories IQsynthesis COMPUTER 107A-Ductless fume hoods Kopella Analytical Services pION Inc. Flow Sciences, Inc. APPLICATIONS XenoBiotic Laboratories, Inc. Organix Inc. 56-Software YourEncore, Inc. 110-Filters PCI Synthesis Accelerated Technology Lab Avery Filter Co. PolyOrg Inc. 79-Safety Eastern Scientific Co. Bio-Rad Labs, Informatics Div Fisher Global Chemical Prime Organics Molecular Knowledge Systems 112-Freeze dryers 80-Spectroscopy Eastern Scientific Co. POLLUTION Polymer Standards Serv,USA Inc Chemir Analytical Services 114-General laboratory CONTROL CONSULTING, Complete Analysis Laboratories 80B-Testing Laboratory equipment 148-Instruments MANAGEMENT Anresco Inc Allen Datagraph,Inc. Rudolph Instruments 57A-Executive Search Case Consulting Labs., Inc. American Instrument 149-Standards On Assignment Lab Support Chemir Analytical Services Cargille Laboratories Cambridge Isotope Laboratories Eastern Scientific Co. 59-Patents Columbia Analytical Services 150-Tests Complete Analysis Laboratories Glas-Col Arendt Associates IP Group KNF Neuberger Columbia Analytical Services Banner & Witcoff, Ltd. Elemental Analysis Corp Laboratory Compliance Services Scientific Asset Management, L QUALITY CONTROL 60-Research Matech Associates Shimadzu Scientific Instrument pION Inc. Polymer Standards Serv,USA Inc 115-Germicidal lamps 151-Quality control SOCMA ValQual Intl. Hellma Cells ValQual Intl. CONSULTING 81-UV analysis 116-Glassware SAFETY Complete Analysis Laboratories G. Finkenbeiner Inc. SERVICES pION Inc. Quartz Plus Inc. 156-Equipment 63-Biomedical Wilmad/Lab Glass Smiths Detection-Danbury ValQual Intl. DETECTORS 119A-Labware DOCUMENTATION 64-Chemical Process 84A-Discharge ionization Cargille Laboratories The Catalyst Group Resource GOW-MAC Instrument Co. 120A-Light sources 158-Custom lab books Scientific Bindery 65-Contract research 85-Flame ionization Hellma Cells Chemir Analytical Services GOW-MAC Instrument Co. 122-PID lamps 159-Notebooks and stockbooks Scientific Bindery Organix Inc. 86-Gas leak Hellma Cells pION Inc. GOW-MAC Instrument Co.

22 The Nucleus October 2008 PRODUCTS & SERVICES DIRECTORY 160-Production control books 168-Gratings 176-UV visible pION Inc. Scientific Bindery Hellma Cells Hellma Cells Polymer Standards Serv,USA Inc 161-Quality control books 171-IR & UV cells pION Inc. ValQual Intl. Scientific Bindery AABSPEC Instrumentation Corp Hellma Cells EDUCATION & SUPPLIES Scientific Bindery 172-Mass PUBLICATIONS 181-Solvents & thinners SPECTROMETERS Acquisition Solutions 179-Books,journals,monographs Cambridge Isotope Laboratories 164-Atomic absorption Bruker Daltonics Photonics Spectra/Laurin Publ. instruments International Equip Trading 179B-Training & education Technology Exchange Corp. Waters Corporation American Inst. of Chemists,Inc To be in next year’s Guide, 166-Emission 174-Raman The Chem Show contact Vince Gale at: Hellma Cells Headwall Photonics, Inc. Chromatography Forum Del Val phone: 781-837-0424, JASCO Excel for Scientists&Engineers 167-Fluorescence Northeastern University e-mail: OLIS, Inc. [email protected]

NESACS–GDCh jahrssymposium is an international fke; both of these folks (and many oth- conference, there are others whom I ers) became close friends during their Continued from page 8 call friends from countries other than time here in August 2007. Tom described additional benefits: Germany: Nuno (Belgium), Bartek The most prominent effect was the “Being a Ph.D. student at that time, I (Poland), and Martina (Czech Rep.) development of my professional net- was in the process of looking for invited me into their lunch group in work. This occurred as a direct result groups suitable for postdoctoral Konstanz, and we have kept in touch of the exchange. In 2007, I became research. The lab I was most interested since. The other Tom, Tom Grossmann involved as the Career Chair for the in was the one of Professor Verdine at (vide supra) and I have kept in touch, NSYCC and President of the Boston Harvard University. In addition to the and I am sure that when he arrives in University YCC. Over the course of presenting scientific research at the the Boston area, he will be more than two years, I met and introduced myself ACS meeting, I had the chance to visit willing to explain the many positive to scores of people in industry from Harvard and meet Professor Verdine in effects for the applicants to the pro- across the section and throughout the Cambridge. Our first face-to-face meet- gram. During the 2006 exchange, I region. ing paved the way for postdoctoral also met Helke Doering and Jens Bref- continued on page 24 work in his lab, which I plan to begin in early 2009. Besides the direct bene- fit of my postdoctoral plans from the exchange program, I value the experi- ences and the people I met. I hope this program between the NESACS and the GDCh will continue into the future, giving many students from both sides of the Atlantic an opportunity to get to know each other.” As the current chair of the NSYCC, I can comment on a few of the positive outcomes from my partici- pation in the 2006 exchange to Kon- stanz. My personal network of colleagues within the international chemistry community expanded greatly. I have kept in touch with sev- eral of the organizers and atten- dees from the conference. There were a couple of guys named Tom with whom I have kept in contact over the years. Thomas Haas was one of the Konstanz organizers, and he and I developed a friendship over the week. He knows that he has a friend and col- league in Boston. As the Frueh-

The Nucleus October 2008 23 Report from NERM Golf Tournament NESACS–GDCh

Continued from page 9 Continued from page 10 Continued from page 23 of National Chemistry Week activi- send any comments or suggestions to An important contact I made ties for the Northeastern Local Sec- Amy Tapper and Harry Mandeville at through the Career Chair position was N tion. [email protected]. with ACS Career Services guru, Dan • The Stanley C. Israel Regional Eustace. As Dan and I came up with a Award for Advancing Diversity in strategy for applying and interviewing the Chemical Sciences to Todd for my future position in industry, he Pagan (National Technical Institute provided helpful suggestions for refin- for the Deaf and the Rochester (NY) ing my story and my message. He also Institute of Technology) for his work offered introductions to his own col- in educating hearing-impaired stu- leagues, already in industry. These dents toward careers in the chemical introductions and suggestions resulted in interviews and marked improvement sciences. Third-place team- Mahesh Padval, Ben Andru- saitis, Mark DaFonseca, Darrin Sloan of interview skills. Expansion of one’s • The ACS Regional Industrial Inno- own professional network is crucial to vation Award to Dana Bookbinder, successfully obtaining the career of Ming-Jun Li, and Pushkar Tandon choice. A strong professional network (Corning, Inc., Corning, NY) for and great career advice can mitigate their work in producing air-glass minor and major glitches. For me, composite optical fibers. whether in Konstanz, Germany or • The ACS Northeast Region Award Cambridge, Massachusetts, the Ger- for Achievements in the Chemical man Exchange has provided numerous Sciences to Abraham Clearfield opportunities to expand and strengthen Second-place team- Gary Kelley, Steve Trahan, my professional and social networks. (Texas A&M University) for his Dave Rogers, Anthony Tavalone work with layered phosphonates. When the two networks intersect, life changes can occur. The Board of Directors of the North- Carl Christianson (Boston Col- east Region of the ACS, Inc., held its NERM 2009 will be hosted by the lege) and his wife, Jolene Schuster annual meeting on July 2; it unani- Connecticut Valley Local Section on (Dartmouth College), each applied for mously voted to commend Willem October 7-10 at the Hartford Hilton in the German exchange and were chosen Leenstra (University of Vermont; Hartford, Connecticut, with Julianne during the interview and selection Green Mountain Local Section), the Smist as the General Chair and Tyson process for the most recent exchange General Chair of NERM 2008, for Miller (University of Connecticut) and to Rostock. They wanted to “put into leading the organizing committee of Edward Fitzgerald (Trinity College) as context how the German Exchange has this very successful NERM. The the Program Chairs; helped to shape, as a couple, [their] Board re-elected Christopher Masi . Because future scientific careers. The German (Westfield State College; Central Mas- the Middle Atlantic Regional Meeting Exchange was very influential for both sachusetts Local Section) and Wayne (MARM) will not meet in 2009 and our scientific careers. Traditionally, Jones (SUNY Binghamton; Bingham- NERM will lead into the Columbus science is thought to be an individual ton Local Section) to two-year terms Day weekend and New England endeavor. Due to the ever-increasing (2009-10) as Secretary and Treasurer, foliage displays, attendance of at least need for collaborative research in order respectively; continuing as Chair and 500 (and most likely significantly to advance a particular field of science, Vice Chair of the Board are Julianne more) is anticipated. Martin Walker the ability to utilize networking and Smist (Springfield College; Connecti- (SUNY Potsdam; Northern New York communicational skills is becoming cut Valley Local Section) and Richard Local Section) will serve as the Gen- more important. By participating in Cobb (Eastman Kodak; Rochester eral Chair for NERM 2010, June 2-5. the German Exchange, not only were Local Section), respectively. An expression of interest has been continued on page 25 The financial condition of the advanced by the Central Massachusetts Northeast Region, Inc., is very good Local Section to host NERM 2011 in due to the financial success of the 2005 the Worcester area; programmatic and Salt Lake City in March 2009. The and 2006 Northeast Regional Meet- logistical support could be made avail- Rochester Local Section is preparing a ings. Sinking fund loans of $4,000 able through the Northeastern Local bid to host NERM 2012. each have been provided to NERM Section. Christopher Masi will investi- The Northeast Region Board will 2009 and NERM 2010; the loans will gate the possibility of organizing the meet next during NERM 2009, Octo- ber 7-10, at the Hartford Hilton in be paid back if the net financial out- meeting, and will make a decision N comes of the meetings are positive. prior to the ACS National Meeting in Hartford, CT.

24 The Nucleus October 2008 BUSINESS DIRECTORY NESACS–GDCh SERVICES SERVICES

Continued from page 24 we able to attend a scientifically stimu- lating conference, but also we had numerous opportunities to work on communication skills with young chemists from different disciplines, backgrounds, and cultures. Having taken part in larger conferences in the past, we both found this to be an engaging and rewarding experience.” Carl and Jolene explained that, “prior to this exchange we had been considering several labs in Europe for possible postdoctoral positions. After interacting with faculty members and students during our time in Germany, we were intrigued by the idea of living and working there. This winter we will be moving to Berlin, Germany, to do our postdoctoral research. Having par- ticipated in the exchange, we have a group of friends and colleagues already in the area. We know that this will make the transition easier for us. We would highly recommend applying for spots on the next exchange to Germany, for the scientific, cultural and social benefits that it can and will yield. The connections and friendships that we made on the exchange are things for which we will always be grateful.” As detailed in these personal accounts, the German Exchange Pro- gram has influenced the career choices, as well as the professional and social networks, for many YCC and JCF members. One never can predict when one’s social and professional networks will intersect, resulting in a synergism that delivers positive effects for a life- time. It seems that through the years, the initial expectations have been met and exceeded, and we would all like for the program to continue. We strongly encourage interested students within the Northeastern Sec- tion to seek out their NSYCC Campus Representatives as well as YCC mem- bers at our events (www.nsycc.org). If you have questions, don’t hesitate to ask ([email protected]), and by all means, complete the application for the 2009 NESACS-GDCh Exchange Program to Essen, Germany. N

The Nucleus October 2008 25 BUSINESS DIRECTORY SERVICES SERVICES SERVICES

26 The Nucleus October 2008 BUSINESS DIRECTORY SERVICES SERVICES CAREER SERVICES

Index of Advertisers Am. Instrument Exchange...... 27 Arendt & Associates IP Group...... 26 Cambrex Corporation...... 27 Chemir Analytical Services...... 26 Columbia Analytical Services...... 9 CreaGen Biosciences ...... 7 DuPont Analytical Solutions...... 26 Eastern Analytical Symposium ...... 2 Eastern Scientific Co...... 8 Front Run OrganX, Inc...... 25 G. Finkenbeiner, Inc...... 25 HT Laboratories, Inc...... 26 Huffman Laboratories, Inc...... 26 IQSynthesis ...... 27 Mass-Vac, Inc...... 23 Micron Inc...... 26 New Era Enterprises, Inc...... 25 NuMega Resonance Labs...... 26 Organix, Inc...... 26 PCI Synthesis ...... 4 PolyOrg Inc...... 25 Robertson Microlit Labs...... 26 Schwarzkopf Microanalytical ...... 25 Waters Corporation ...... 25

The Nucleus October 2008 27 Harvard, MA 01451 19 Mill Road

Oct 7 Oct 21 Prof. Mary K. Pflum An Organic Symposium Sponsored by Bristol- Boston College, Merkert 130 Myers Squibb 4:00 pm Dr. Rodney Parsons Prof. Bernadette T. Donovan-Merkert (Univ. Prof. Larry Overman (U.C., Irvine) North Carolina, Charlotte) “Recent Studies in Alkaloid Total Synthesis” “Electrochemically-Promoted Catalytic Boston College, Merkert 130 4:00 pm Asymmetric Syntheses: Zapping Our Way to Prof. Barry Snider (Brandeis Univ.) Enantiomeric Purity” TBA Univ, New Hampshire, Room L103 Univ, New Hampshire, Room L103 11:10 am 11:10 am Oct 8 Oct 22 Dr. Ira Krull (Northeastern Univ.) Dr. Brian Blagg (Univ. Kansas) “Characterization of Recombinant Human “Designing Old Drugs for New Targets, a Case Monoclonal Tissue Necrosis Factor-alpha Study with Novobiocin” Antibody Using Capillary Isoelectric Focusing, Northeastern Univ. 129 Hurtig Hall Cation Exchange, Size Exlusion 12:00 noon Chromatography and Mass Spectrometry” Prof. Q. Jason Cheng (U.C., Riverside) Northeastern Univ. 129 Hurtig Hall “Supported Lipid Membrane Interfaces for 12:00 noon Biosensing with Surface Plasmon Resonance” Dr. Christopher Doona, (U.S. Army NSRDEC) Boston College, Merkert 130 AMERICAN CHEMICAL U.S. POSTAGE PAID

NONPROFIT ORG. “Comparing the Quasi-chemical and other 4:00 pm NORTHEASTERN models for controlling food borne microbes SOCIETY SECTION Charles E. Kolb (Aeordyne Research Inc., MA.) using novel technologies.” TBA U Mass, Dartmouth, Building Group II, U. Mass, Dartmouth, Building Group II, Room 118 4:00 pm Room 118 4:00 pm Peter Ford (U.C., Santa Barbara) Oct 27 TBA MIT, 6-120 Rustem Ismagilov (University of Chicago) 4:00 pm TBA Oct 14 Harvard, Pfizer Lecture Hall 4:00 pm Calendar Prof. Phil Dawson Oct 28 Boston College, Merkert 130 4:00 pm Prof. John Koh Check the NESACS Homepage Boston College, Merkert 130 Prof. Marisa C. Kozlowski (Univ. Penn.) 4:00 pm for late additions: Univ, New Hampshire, Room L103 http://www.NESACS.org 11:10 am Oct 29 Oct 15 Jose Rivera (University of Puerto Rico) Note also the Chemistry Department web “Adventures in Supramolecular Space Using 8- pages for travel directions and updates. Dr. Melisenda J. McDonald (Sandy), (UMass Arylguanine Derivatives” These include: Lowell) Harvard, Pfizer Lecture Hall http://chemserv.bc.edu/seminar.html TBA 4:00 pm http://www.bu.edu/chemistry/events/ U Mass, Dartmouth, Building Group II, http://www.chem.brandeis.edu/colloquium.shtml Room 118 Dr. Terry Bowlin (Microbiotix, Inc) http://www-chem.harvard.edu/events/ 4:00 pm “Discovery and Development of Novel Small http://web.mit.edu/chemistry/ Oct 16 Molecule Inhibitors of Botulinum Neurotoxin A” www.chem.neu.edu/web/calendar/index.html U Mass, Dartmouth, Building Group II, http://chem.tufts.edu/seminars.html [CHEM.] Professor Masahiro Terada (Tohoku University, Room 118 4:00 pm http://ase.tufts.edu/chemical/seminar.htm Japan) Peter J. Sadler (Warwick University, UK) [CHEM. ENGG.] “Enantioselective Catalysis by Chiral Bronsted Davison Lecture http://www.chem.umb.edu/ Acid/Base through Hydrogen Bonding as MIT, 6-120 4:00 pm www.umassd.edu/cas/chemistry/seminars.cfm Strategic Interaction” Oct 30 www.uml.edu/Dept/Chemistry/speakers.html Boston College, Merkert 130 http://www.unh.edu/chemistry/seminars.html 4:00 pm Prof. Emmaneal Lacote (Université Pierre et Oct 1 Oct 17 Marie Curie, France) TBA Dr. Mark M. Turnbull (Clark University) Kenichiro Itami (Nagoya University) Boston College, Merkert 130 “Design and Synthesis of Low-Dimensional TBA 4:00 pm Magnetic Lattices”. Harvard, Pfizer Lecture Hall Laurence Barron (University of Glasgow) U Mass, Dartmouth, Building Group II, Room 4:00 pm TBA 118 Chris Abell () Harvard, Pfizer Lecture Hall 4:00 pm Novartis Lecture in Organic Chemistry 4:00 pm Oct 2 TBA MIT, 6-120 Jose Rivera (Univ. Puerto Rico) Troy van Voorhis, (MIT) 4:00 pm TBA TBA Oct 20 MIT, 6-120 4:15 pm Harvard, Pfizer Lecture Hall Notices for The Nucleus 4:00 pm David C. Corey (U. Texas Southwestern Medical Calendar of Seminars Oct 6 Center) should be sent to: Bristol-Myers Squibb Lecture in Organic Stephen L. Buchwald (MIT) Synthesis Sheila E Rodman The Max Tishler Prize Lectures Harvard, Pfizer Lecture Hall 250 Kennedy Drive TBA 4:00 pm Unit #403, Malden, MA 02148. Harvard, Pfizer Lecture Hall N E-MAIL: serodman(at)hotmail.com 4:00 pm