Ecosystems for innovation Claire Ruskin CEO, Network Innovation in Cambridge

– how did it happen, how can we grow it and is it repeatable elsewhere?

Material from Shai Vyakarnum – Judge Business School Tim Minshall – Institute for Manufacturing Claire Ruskin – CEO Cambridge Network Steven Ireland – East of England Inward Investment

Cambridge Network – II EE www.cambridgenetwork.co.uk What’s special about Cambridge? The starting point … • A global ‘top five’ university: The has 800 years at the top • Proximity to London and Europe : 5 international airports within 2 hours • Highly qualified employees: > 40% of people living in Cambridge having a high level qualification (compared to the national average of < 20%) • A few hi-tech companies back in the fifties • The start of a world class contract R&D cluster (the consultancies) from 1960

• => Evolving to a hi-tech cluster supporting > 143,000 jobs in the region. The cluster generates the equivalent of an NPV of £53bn in GDP. • => Good quality of life: Polls highlight Cambridgeshire as one of the best places to live in the UK • => Attitude: a good feeling about success and starting something new

Cambridge Network – II EE www.cambridgenetwork.co.uk Why will Cambridge continue to have competitive advantage? • Diverse science base and research infrastructure, bringing excellent people to the Universities, business and medical organisations • Practice at innovation on demand as well as commercialisation • Collective learning and networking systems • Entrepreneurial business community – enthusiastic to participate in local, regional, national and international programmes of innovation, change and new business creation • Established Science Parks and Innovation Centres, good infrastructure of services, wealth, experience, board members, philanthropy, drive to succeed

Cambridge Network – II EE www.cambridgenetwork.co.uk The East of England Region

• 5.5 million people • $160 billion economy - 10% total GDP of the UK • One of four regions that contributes positively to the UK economy • Largest pool of Angel and VC funding in Europe outside of London • Highest expenditure on R&D in the UK • 2500 internationally owned companies • Unique mix of university research, rapidly growing SME’s and major multinationals working in closely networked clusters

The highest concentration of VC funded companies in the UK and (probably) in Europe

Cambridge Network – II EE www.cambridgenetwork.co.uk Government has policies that foster innovation in the UK …

Technology Strategy Board • Competitions • Knowledge Transfer Networks • Knowledge Transfer Partnerships Enterprise Europe Network R&D Tax Credits Business Network SIG’s

… but Government hasn’t had much impact on Cambridge, where companies have mostly been funded privately and nurtured by serial entrepreneurs and the ‘ecosystem’ …

Cambridge Network – II EE www.cambridgenetwork.co.uk The University of Cambridge has been #1 in the world for the last two years

• A strong attractor to top academics and top students from around the world • 12,000 undergrads, 6,000 graduate students, 2,000 post-doctoral, 1600 academic staff • € 560M turnover • Six “Schools”: – Arts and Humanities – Biological Sciences – Clinical Medicine – Humanities and Social Sciences – Physical Sciences – Technology • Dates from 1209 so attracts visitors to the region

Cambridge Network – II EE www.cambridgenetwork.co.uk University of Cambridge

• More Nobel Prize winners than any other institution The University of Cambridge has 81 Nobel Prize winners; more than any other university, or country (with the exception of the UK and USA) in the world. This includes a Prize in Physics for the tunneling in superconductors and semiconductors. (Source: www.cam.ac.uk ) • Ranked No 1 in the World The University of Cambridge is the top ranking Euopean University in the World. Source: Shanghai Jiao Tong Academic Ranking of World Universities 2011 • Contribution to the Economy >250 active companies can trace their origins back to knowledge transfer from the University. 70 companies have spun-out directly from the University, >$50M raised for commercialisation since 2008, >$15 pa licensing/consulting • First Class Research Of the top ten UK universities, according to the Shanghai Ranking 2005, Cambridge achieved the highest income (£254m) for research.

Cambridge Network – II EE www.cambridgenetwork.co.uk A world class cluster of technical consultancies

• Four world-renowned consultancies doing contract design and development

• Another 12 consultancies growing up in the cluster

• Considerable combination of technical excellence with commercial reality

• First class resources, funded by international companies but run by local experts

Cambridge Network – II EE www.cambridgenetwork.co.uk Steve Barlow Caroline Robert Swann Garey Phil O’ Donovan Aphamosaic Smartbead James Collier Andrew Dames Technologies Acquired by Synaptics Glenn Collinson Polatis Cambridge Silicon Mark Howard Acquired by Elumin Holotag Radio Richard Doyle founded by Dr. Hans Chris Andrew Dames Sensopad Wagner Davies Cyan Sentec Technologies Stuart Hendry tants Pelikon Andrew Dames Chris Fryer Technology Absolute Gavin Troughton Chris Barnardo Sensors Adrian Lucas Sphere Medical Mike Willis Roger Pivotal Imerge David Paton David Bending Roundpoint Millar Resources 3D Molecular Mike Willis Cambridge Physical Sciences INCA Digital Sciences Steve Temple Gordon Edge, Elizabeth Hill Xaar Printers Bob Pettigrew Mark Tracy Scientific Nigel Playford Bill Baxter Prelude QuantumBEAM Generics Ionica Will Eve Robert Hook Gordon Edge, Bob Graham Martin Paul Anson Gordon Pettigrew, Alan Green Colin Gray Mike Payne Tim Eiloart Edge Adaptive Screening ELMJET Diomed Tony Raven Will Eve CCL Flying Null PA Mike Crossfield Acquired by Graeme Minto Domino 1960 1970 TTP Videojet David Paton Ross Green, Mike Kellaway Robin Wavedriver Technologies Gerald Avison Smith-Saville Acquired by DCS Cambridge Signal Process PowerGen Mike Storey Mass Spectrometry Ltd Automation Richard Archer Symbionics Partnership Xennia Until 1985 Collin Demerged from Technology Dennis Smithers TTP Group Alan Hudd Plextek TTPCom Fielder Myriad 1986-1990 Tony Milbourn Transversal John Cassells Barrie Griffiths David Yip Steve MullockKore ip.access David McKay Technology Acquired by 1991-1995 Acquired by Mettler-Toledo Cadence Ubinetics Ali TTP Acumen Pourtaheri Tality Ventures Bioscience 1996-2000 David Cornell TTP Richard Philpott Hi-tech start-ups spawned from the Cambridge consul Cambridge the from spawned start-ups Hi-tech Yuno Ltd Radiant Vivid Creativity LabTech John Cassells Networks Stephen Eason Partnership Fen Anne Miller Acquired by Vetura 2001-2002 Technology Cambridge Network – II EE www.cambridgenetwork.co.uk Tin Bustin, Ciaran McAleer V(Sept 2005) – not to be used or copied without permission Copyright – Y.M.Myint -, Dr. Shailendra Vyakarnam RealVNC Virtual Network Merged with Level5Network Computing Andy Hopper Steve Pope Globespan Hi-tech start-ups Ubisense Andy Hopper Peter Warton Andy Hopper Cambridge Andy Hopper associated with Andy Ward Broadband IPV (Telemedia Hermann Hauser Acquired by Cambridge Acquired by American Pete Steggles Acquired by AT &T Western Systems) Virata(ATML)Andy Hopper Microwave University Adaptive Multiplex Simon Elliott Broadband Hermann Hauser Corp TerraPrise Amadeus Capital Partners VBN Olivetti Hermann Hauser online Tensails nCipher Splashpower Richard Green Research Lab Alex van Someren Mike Muller Andy Hopper Acquired by Acquired by Nicko van Someren Tudor Brown ARM Broadcom Lily Chang GE Jamie Urquhart ANT Element 14 Icera James Hay Richard Green Small Acquired by Alex van Someren Authur Chance World Olivetti Nicko van Someren Stan Boland Stan Boland Simon Knowles Simon Knowles Dick NewellCambridge Interactive Systems Part of DAKO John Snyder DakoCytomation - Dick Newell, Tom Sancha Diagnostics Webtop Acorn Merged with Cytomation Charles Lang Hermann Hauser, Chris Keightley Shape Data Hermann IQ Bio Inc Peter Duffett-Smith Smartlogik Hauser Netchannel CPS Hermann Hauser Acquired by Acquired by Dialog CAD Hermann Hauser Top Jack Lang NTL Cambridge Jack Lang Electronic Share Jack Lang express University Information Acquired by E* Muscat Laser-Scan Analysys CDT Trade John Snyder R. O. Frisch Enterprise David Cleevely Richard Friend Martin Porter Until 1985 Accelerator John Snyder Cambridge Richard Friend Adam Twiss 1986-1990 Semiconductor Zeus Plastic Logic David Reeves Technology Gehan Amaratunga Florin Udrea Pilgrim Beart David Cleevely ActiveRF ART 1991-1995 Cambridge Hermann Hauser Network Daniel Hall Collin Ager Alec Broers Antenova Garraint Davies Saviso Group Innovia Pilgrim Beart Polight Cambridge 3G Adam Twiss Technologies 1996-2000 Bryan Amesbury Stephen Elliott David Cleevely Pavel Krecmer M-Spatial 2001-2002 Adrian Cuthbert Cambridge Network – II EE www.cambridgenetwork.co.uk Jon Billing V(Sept 2005) – not to be used or copied without permission Copyright – Y.M.Myint -, Dr. Shailendra Vyakarnam Acquired by Becker Underwood Merlin Biosciences William Bains Chris Evans Arakis John Caldwell Iain Cubitt Greg Winter Pestex Changed its name to Diversys Merged with Andy Amedis MicroBio Group Xenova Group Cyclacel Richards pharmaceutical RiboTargets Ltd Microscience Vernalis Merlin Ventures Simon Sturge Ark Therapeutics Chris Evans Chris Evans Iain Cubitt Martin Davies Acquired by Vectura Celsis Axis Genetcs Toad Greg Winter Chris Lowe Prometic ReNeuron Chris Evans Cerebrus BioRobotics Daivd Chiswell J. McCann Biovex Biosciences ChiroTech Chris Evans CAT Chris Evans Cambridge Inc Chris Evans Rapigene Celltech Alan Munro Chris Lowe Enviros Sensors Smart Enzymatix Cantab Merged by Chris Evans Chris Lowe Holograms Pharmaceuticals Celltech Chris Lowe Ken Jones Group Chiroscience MRC LMB Affinity chromatography Chris Evans Genzyme 1960s Chris Lowe Purely Proteins Daniel Roach AGC Alan Goodman LiDCO (UK) - 1985 David Bailey Alan Goodman 1984 Philip Dean Terry O’Brien Alan De Novo CeNes Cambridge David Bailey Alan Goodman Goodman University AdproTech Alan Peter Lachmann CORE ATM Biotica Technology Goodman Alan Until 1985 Peter Leadlay Goodman Kudos Jim Staunton Daniel Roach Oxford Bimedica Pharmaceuticals Alan Alan Goodman . Mark Bodmer Stephen Jackson 1986-1990 Hexagen Goodman Peptide Acquired by Incyte Avlar Therapeutics BioVentures Metris Lorantis Alan Goodman Now Acambis Mark Bodmer 1991-1995 Therapeutics Daniel Roach Amura Paradigm Stephen Smith Salix Alan Therapeutics Steve Charnock-Jones pharmaceutical Goodman Holometrica Mark Carlton Astex Abcam Roger Millington Solexa Alan Sense Technology Jonathan Milner 1996-2000 Goodman Proteomics David Cleevely

iotech start-ups from Cambridge University and iotechfrom start-ups University Cambridge Jonathan Blackburn Jonathan Milner Chris Abell B other individuals David Cleevely Cambridge Theranostics Paul Goldsmith Akubio MC Ivan Petyaev Daniolabs David Klenerman, Cambridge Network – II EE www.cambridgenetwork.co.uk2001-2002 V(Sept 2005) – not to be used or copied without permission Copyright – Y.M.Myint -, Dr. Shailendra Vyakarnam Working together in technologies – interaction with humanities, arts and social sciences and bringing in the new medi-park, started at our world-class teaching hospital, Addenbrooke’s

BIO TECH INFO TECH Pharmaceuticals Genomics Hardware Diagnostics Bioinformatics Software Research/Info Proteomics Communications Tools Industrial Biochips Bioelectronics Nanodevices Microfluidics Nanosensors Nanobiotechnology Nanoelectronics Drug Delivery

NANO TECH Electrical Structural Biomedical Energy & Environment

Cambridge Network – II EE www.cambridgenetwork.co.uk 1600

1400

1200

1000

800

600

400

200 Number of High Tech Companies Tech of HighNumber 0 1960 1970 1980 1990 2000

www.cambridgenetwork.co.uk Hi-Tech Jobs, 1981

Hi-tech jobs 1981 Up to 1000 1000-2500 2500-5000 5000-10000 Over 10000

GCP area Source: ABI, LFS, PACEC

www.cambridgenetwork.co.uk Hi-Tech Jobs, 1991

Hi-tech jobs 1991 Up to 1000 1000-2500 2500-5000 5000-10000 Over 10000

GCP area Source: ABI, LFS, PACEC

www.cambridgenetwork.co.uk Hi-Tech Jobs, 2001

Hi-tech jobs 2001 Up to 1000 1000-2500 2500-5000 5000-10000 Over 10000

GCP area Source: ABI, LFS, PACEC

www.cambridgenetwork.co.uk The Cambridge Science Park

• First and most prestigious science park in the UK, established 1970 • >100 companies • Mix of start-ups, spin-outs and subsidiaries of multinational corporations • >5500 employees on site • A mix of businesses : – Bio-medical/pharmaceutical, Bio-technology engineering – Technology, especially wireless – Various Software/Computing – Game development – Cleantech - energy, environmental – Consultants – Support services e.g. patent agents

Cambridge Network – II EE www.cambridgenetwork.co.uk Research Establishments and Science Parks

Cambridge Network – II EE www.cambridgenetwork.co.uk Networks help the confidence and capability grow

Cambridge Network: bringing people together, to raise Cambridge’s game and collaborate for shared success We bridge gaps between academia, business and medical worlds in Cambridge UK, and offer a contact point for the world

• Events – magnet to new business, trigger for productive relationships, sharing specialists and views • Training – peer learning and shared training in Cambridge • Recruitment – magnet to recruits for Cambridge • Directories – companies, people, services, skills, news • Shared service - the network of networks, collecting views from Cambridge hi-tech business and being a channel for dialogue with others

Cambridge Network – II EE www.cambridgenetwork.co.uk [email protected] Typical members in the Cambridge Network include start-ups and mature companies

Multinational Consultancies corporations

www.cambridgenetwork.co.uk Who are the members of Cambridge Network?

2%

5% 6% Businesses

Individuals

17% International businesses

Charities

65% Founders and Founder members

Cambridge Network – II EE www.cambridgenetwork.co.uk Cambridge start-ups – ten have exceeded valuations of $1bn and others follow

Some examples of well-established local start-up companies • ARM – RISC Processors – Founded in 1990 – £263M turnover in 2006, 20% profit – £2bn market capitalisation • Cambridge Silicon Radio – Single-chip Bluetooth radio – Founded in 1996 – Market capitalisation £0.8bn, turnover £400M, 20% profit • Xaar – Founded in 1990 – Industrial IJP heads and inks – 300 employees, £50M turnover

Cambridge Network – II EE www.cambridgenetwork.co.uk Success requires excellence in research and also in commercial development

University strengths in ‘R’ Commercial strengths in ‘D’ • Design, development, prototyping, batch production,..

www.cambridgenetwork.co.uk Companies from outside see the value of Cambridge and join in

Cambridge Network – II EE www.cambridgenetwork.co.uk