04/03/13 CURRICULUM VITAE for Dr. JESSICA NAKIYINGI MIIRO
Objective: To offer epidemiological/statistical/research/academic/public health skills to organisations engaged in public health, research, academia, and medical work. Her main contributions would be in proposal writing, protocol development, data management, analysis, literature searches, lecturing, mentoring, tutoring, report writing, publications and presentations.
Personal biodata: Female, Married with children, Ugandan by birth, currently Senior Statistical Epidemiologist at the MRC/UVRI Uganda Research Unit on AIDS.
Contact: Address: MRC/UVRI Uganda Research Unit on AIDS, ℅ Uganda Virus Research Institute, Plot 51 59, Nakiwogo Road, P O Box 49, Entebbe, Uganda. Telephone: +256 (0) 772 408316 (Mobile), +256 (0) 417 704000 (Work) Fax: +256 (0) 312 321137 Emails: [email protected] , jessica.nakiyingi [email protected]
Profession: Statistical Epidemiologist
Jessica is a Senior Statistical Epidemiologist working with MRC/UVRI Uganda Research unit on AIDS with over 15 years in research involving clinical trials, field epidemiology studies, community based trials, and Information, Education and Communication (IEC) activities; and 20 years of statistical and data management skills. She has been the lead Statistician in 17 scientific publications including HIV incidence in a general rural population cohort, and recently in high risk fishing communities. She has 6 years experience in mid level management, as head of the MRC statistics section which handles all the quantitative data for MRC/UVRI. During this period there were over 20 concurrent studies whose data management and analysis she supervised, which equipped her with skills of: supervising; training; and monitoring data entry, data cleaning, and data management; while maintaining high data quality in timely and efficient ways.
Training in statistics and analytical methods and skills has been part of her job for the last 15 years. From 2001, she became involved in various activities of university postgraduate education including lecturing MSc (Clinical Epidemiology) students at Makerere University, and tutoring MSc students at London School of Hygiene & Tropical Medicine (LSHTM). Since 2007, MRC introduced annual 2 weeks' courses in Epidemiology and Statistics for scientists from within Uganda and Sub Saharan Africa. She has been involved in organising and conducting these courses, which has greatly improved her training skills especially to individuals with limited statistical knowledge and skills.
Jessica is hardworking and dependable, a team player who meets her end of the job in time, and an asset you would want to use or add to your organisation. Below are more details about her:
Educational Background University Education 2011 Post Graduate Diploma in Epidemiology and Population Health by research: London School of Hygiene & Tropical Medicine, United Kingdom 2010 Doctor of Philosophy (Epidemiology and Statistics): University of London, United Kingdom (Topic: The impact of orphanhood on education outcomes in rural Uganda. Are we approaching universal education?) 1997 Master of Science (Epidemiology and Population Health): Australian National University, Canberra, Australia. (Topic: Population composition and Change in an HIV infected Rural Ugandan Community) 1994 Graduate Diploma in Statistics: Australian National University, Canberra, Australia. 1990 Bachelor of Statistics (Upper Second Class Honours): Makerere University, Kampala, Uganda. (Research Topic: A Statistical Analysis of the Economic performance of Maganjo Grain Millers)
Pre-University Education 1984 A Level 3 Principal Passes Gayaza High School, Uganda 1 04/03/13 1981 O Level Division 1 Gayaza High School, Uganda 1977 Primary 7 Grade 1 Jinja Karoli Girls' School, Uganda
Short courses 2012 Mar Monitoring & Evaluation course for Senior UVRI Officers, Entebbe, Uganda 2011 Aug Effective policy communication, UVRI, Entebbe, Uganda 2008 Nov/Dec Online Distance Learning tutoring course, Oxford Brookes, UK, Web based 2003 Feb The John Hopkins School of Hygiene and Public Health, Human subjects Research Education, Web based 2002 Jul Good Clinical Practice, Kampala, Uganda 2001 May Presentation skills, MRC training group form UK 2001 May Managing your research, MRC training group from UK 2000 Feb Topline Management Course, Trianagam PTY, Johannesburg, South Africa 1998 Sep Advanced Course in Epidemiological Analysis, LSHTM, London, UK 1997 Dec Effective Supervision and Management, TACK, Nairobi, Kenya 1997 Jul Relational database management systems using FoxPro for Windows, Entebbe
Scholarships, Awards, and fellowships 2010 HIV trust Research Scholarship (HIVRT10 031) to visit TAZAMA Project, National Institute for Medical Research (NIMR), Mwanza, Tanzania 2005 2009 Medical Research Council (UK) PhD scholarship 1994 1996 AusAID post graduate scholarship 1988 Director’s award for best Statistics practical, Institute of Statistics and Applied Economics (ISAE), Makerere University, Uganda
Working experience Current: 2009 Aug to date Senior Statistical Epidemiologist, MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda 2007 Apr to date Distance Learning Tutor for MSc(PH), University of London (LSHTM), UK 2011 Feb – to date Reviewer BioMed Central open Access journal
Previous: 2009 Nov 10 Jan Consultancy with Marie Stopes International (MSI), London, UK on “Saving Malagasy women’s lives with Misoprostol”. 2009 Oct – Nov Consultancy with WHO on “Data Processing the Survey of WHO’s Immunization and Vaccine Development (IVD) staff in the WHO African Region” 2005 2010 Part time lecturer for in house courses at London School of Hygiene & Tropical Medicine (LSHTM), UK. Courses taught include: Basic Maths; Analysis & Design of Research Studies (ADRS); Statistics for Epidemiologists (STEPH); and Intensive Course in Epidemiology and Medical Statistics (ICEMS) 2005 Dec Data entry with Non Communicable Disease Epidemiology Unit, LSHTM 2001 Jul 05 Sep Senior Programme Statistician/Head of Statistics section, MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda 2004 Sep 05 Sep Trial Statistician on the Fluconazole prophylaxis Trial, MRC, Uganda 2002 Apr 03 Dec Roger’s Fellow (Ms. Sarah Kisa) Supervisor, MRC, Uganda 2001 Nov 05 Sep Mother and Baby Study Trial Steering Committee member 2001 Lecturer MSc (Clinical Epidemiology), Makerere University, Kampala, Uganda 1999 Apri 01 Jul Acting Senior Programme Statistician/Head of Statistics section, MRC/UVRI, Entebbe, Uganda 1996 May 99 Mar Statistician, MRC/UVRI, Entebbe, Uganda 2 04/03/13 1995 May Survey assistant and Data Entry, Intstat Australia Pty Ltd., Ainslie, Australia 1994 Jun Nov Survey assistant, Datacol, 134 Bunda Street, Civic, Australia 1991 Aug 93 Dec Statistical Research Associate, MRC/UVRI, Entebbe, Uganda 1991 Jan Aug Research Officer with International Development Consultants (IDC) Ltd., Kampala, Uganda 1990 Dec Interviewer in the Neonatal Tetanus Survey carried out by the Child Health and Development Centre, Kampala, Uganda 1990 Feb Mar Carrying out a survey for the Kampala Central Business Working Community, Kampala, Uganda
Key tasks for my current job at MRC/UVRI (Aug 2010 – to-date) • To supervise and train Statistics section staff handling epidemiological and social science studies’ data within MRC/UVRI. • To liaise with Senior Scientific staff working on epidemiological studies of MRC/UVRI in study/protocol development, data collection, data analysis, interpretation of results, and writing reports, scientific papers, and presentations. • To conduct statistical analyses and contribute to the current and future scientific work of MRC/UVRI.
Key tasks for my prevous job at MRC/UVRI (Apr 1999 – Sep 2005) • To supervise and train Statistics section staff who handle all quantitative data for MRC/UVRI. • To liaise with other Senior Scientific staff of MRC/UVRI in study development, data collection, data analysis, interpretation of results, and writing reports, scientific papers, and presentations. • To conduct statistical analyses and contribute to the current and future scientific work of MRC/UVRI. • To ensure that an effective and coherent software system is in place for data handling and statistical analyses.
Specific Projects that Jessica has worked on 1. The Pneumococcal Vaccine Trial (PVT) This double blind placebo controlled trial of the 23 valent Pneumococcal polysaccharide vaccine in HIV infected adults was conducted through the Entebbe TASO and Ministry of Health UVRI clinics. Recruitment of subjects started in 1995 and vaccination ended in June 1998. Follow up of this cohort ended in June 2009 at the end of operational studies and prevention trials. Jessica set up the data entry screens, managed the data, and was the only Statistician on this Trial. Several presentations and publications came out of this trial including 2, 20, 22, 23, 26, 38, 40, 41, 46, 49 and 50 below.
2. The General Population Cohort (GPC) This GPC was set up in 1989 in a cluster of 15 neighbouring villages which were expanded to 25 villages in 1999. This cohort has been kept under epidemiological surveillance for HIV infection through annual census, face to face interviews, and sero surveys. Jessica managed GPC data from August 1991 to July 1993, and has since 1993 been doing statistical analysis using this database. For most survey rounds, she was involved in questionnaire design, interviewer training, and survey planning. She used this cohort and data for her PhD research, and is currently supervising statistics section staff working on this project. Publications from this data include: 1, 10, 12, 17, 21, 24, 25, 31, 36, 37, 47, 48, 52, 53, 54 and 55 below.
3. TB and Worm studies These studies were designed to examine the human immune response to Mycobacterium tuberculosis , and interactions between TB, HIV infection and helminth infestation. They used the
3 04/03/13 former PVT cohort and Mulago Hospital. Jessica managed the data for these studies and did some of the statistical analyses. Publications include 28, 29, 33, 34, 35, 43 and 51 below.
4. Masaka Intervention Trial (MIT) This was a community randomised controlled trial, which aimed to determine the effectiveness of a behavioural change intervention, through Information, Education and Communication (IEC) alone or in combination with improved STD management on HIV transmission in an adult population of Masaka district and surrounding areas. This trial started in 1994 and was completed in 2000. Jessica mainly worked with the IEC section which involved behavioural interventions in the community and schools. She managed the data for IEC and did some analyses for both IEC (publications 39, 44, and 45 below) and for the main MIT survey work (publications 27, 30, 32 and 42 below).
5. Rogers Fellowship supervision Between April 2002 and December 2003, Jessica supervised a Rogers Fellow Ms. Sarah Kisa who was attached to the Statistics section. Her topic was “The Development of a Simulation model of the HIV epidemic in rural South Western Uganda, and Investigation of the potential impact of various interventions.
6. The DART Trial The Development of Anti Retroviral Therapy in Africa (DART) was an open label randomised trial evaluating two strategic approaches for management of antiretroviral therapy (ART) in symptomatic HIV infected adults in Africa. The first strategy compared Clinical Monitoring Only (CMO) with Laboratory plus Clinical Monitoring (LCM). The second approach (terminated prematurely) compared Structured Treatment Interruptions (STIs: 12 weeks on, 12 weeks off ART) with continuous ART in patients who achieved CD4 cell counts >=200 cell/mm3 after 24 or 48 weeks on continuous ART. Enrolment at the 4 African sites (JCRC, Academic Alliance and MRC in Uganda, and University of Zimbabwe in Zimbabwe) started in January 2003 and ended in February 2004. Follow up for this trial ended in 2008. Of the 3000 patients in the trial, 1000 were recruited at MRC, Entebbe. Jessica was in charge of the statistics and data management staff in MRC for this trial and coordinated data handling at the MRC site. She was involved in the trial design and protocol development and as such, was a member of the DART trial committee, and was co author on the publications: 4, 5, 7, 8, 9, 11, 14, 15, 16, 18, and 19.
7. Primary prevention of invasive cryptococcal disease using fluconazole prophylaxis This was a double blind randomized controlled trial of fluconazole as primary prophylaxis against invasive cryptococcal disease in HIV infected Ugandans living in Masaka. Its objective was to assess whether routine use of fluconazole as primary prophylaxis in HIV infected African patients was effective in reducing the incidence of invasive cryptococcal disease and all cause mortality. From September 2004, 1540 non pregnant adults with a CD4 count <200 were recruited to the study and randomised to fluconazole 200mg three times a week or identical placebo. Follow up ended in May 2008. Jessica was the trial statistician and member of the Data Monitoring Committee until September 2005.
8. The Fisherfolk communities studies This was a prospective cohort study set up in 2009 to determine HIV incidence, and risk factors for HIV infection, and to describe the molecular epidemiology and the social and behavioural characteristics in fishing populations of two lakeshore districts in Uganda in preparation for future HIV prevention research. Other sub studies on the prevalence of worm infection in these communities; the relationship between schisto and HIV are also being conducted in these communities. Jessica is the Statistician on these studies and supervises statistics section staff working on these studies. Publication 3, and 6 is from this study.
9. The impact of orphanhood and education outcomes This was the research was done for Jessica’s PhD studies. It was carried out within the GPC (study 2 described above). During the study period (1989 2007): parental links for children aged <18 years were established; 18 year time trends of orphan prevalence, orphan incidence, and education outcomes by orphan type (maternal, paternal, and double), calendar period, and age group were also 4 04/03/13 estimated. The aim of this study was to measure and better understand the causal link between child orphanhood and education outcomes, and the relative importance of parental characteristics, children’s attributes, and fostering arrangements in this relationship. A cross sectional study nested within the GPC collected more data on education experiences, parental characteristics, and literacy to enable a relatively comprehensive analysis of the effects of orphanhood on child education. A schools’ education survey on education quality in selected primary and secondary schools was also done. A PhD dissertation (13) on this study is available.
Scientific Papers and Publications 1. Gershim Asiki, Georgina Murphy, Jessica Nakiyingi-Miiro , Janet Seeley, Rebecca N Nsubuga, Alex Karabarinde, Laban Waswa, Sam Biraro, Ivan Kasamba, Cristina Pomilla, Dermot Maher, Elizabeth H Young, Anatoli Kamali1, and Manjinder S Sandhu On behalf of the GPC team. The general population cohort in rural south-western Uganda: a platform for communicable and non- communicable disease studies. Int J Epidemiol. 2013 doi:10.1093/ije/dys234 2. Kerkhoff AD, Kranzer K, Samandari T, Nakiyingi-Miiro J , Whalen CC, Harries AD, Lawn SD. Systematic Review of TST Responses in People Living with HIV in Under-Resourced Settings: Implications for Isoniazid Preventive Therapy . PLoS One. 2012; 7(11): e49928 3. Nazziwa J, Njai H, Ndembi N, Lyagoba F, Asiki G, Nakiyingi-Miiro J , Mpendo J, Nanvubya A, Birungi J, Debont J, Nielsen L, Grosskurth H, Seeley J, Kaleebu P. HIV-1 transmitted drug resistance and evidence of transmission clusters among recently infected antiretroviral naïve individuals from Ugandan fishing communities of Lake Victoria . AIDS Res Hum Retroviruses doi:10.1089/AID.2012.0123 4. Walker AS, Prendergast AJ, Mugyenyi P, Munderi P, Hakim J, Kekitiinwa A, Katabira E, Gilks CF, Kityo C, Nahirya Ntege P, Nathoo K, Gibb DM; DART and ARROW trial teams . Mortality in the year following antiretroviral therapy initiation in HIV-infected adults and children in Uganda and Zimbabwe . Clin Infect Dis. 2012 Dec;55(12):1707 18. doi: 10.1093/cid/cis797 5. Gilks CF, Walker AS, Dunn DT, Gibb DM, Kikaire B, Reid A, Musana H, Mambule I, Kasirye R, Robertson V, Ssali F, Spyer M, Pillay D, Yirrell D, Kaleebu P; DART Virology Group and Trial Team . Lopinavir/ritonavir monotherapy after 24 weeks of second-line antiretroviral therapy in Africa: a randomized controlled trial (SARA) . Antivir Ther. 2012;17(7):1363 73. doi: 10.3851/IMP2253. 6. Janet Seeley, Jessica Nakiyingi-Miiro , Anatoli Kamali, Juliet Mpendo, Gershim Asiki, Andrew Abaasa, Jan De Bont, Leslie Nielsen and Pontiano Kaleebu on behalf of the CHIVTUM study team. High HIV incidence and socio-behavioural risk patterns in fishing communities on the shores of Lake Victoria, Uganda. Sexually Transmitted Diseases 2012 June; 39(6): 433 439. 7. Gibb, D.M, Kizito H, Russell EC, Chidziva E, Zalwango E, Nalumenya R, Spyer M, Tumukunde D, Nathoo K, Munderi P, Kyomugisha H, Hakim J, Grosskurth H, Gilks CF, Walker AS, Musoke P; DART trial team . Pregnancy and infant outcomes among HIV-infected women taking long-term ART with and without tenofovir in the DART trial . PLoS Med 9(5): e1001217 8. Medina Lara A, Kigozi J, Amurwon J, Muchabaiwa L, Nyanzi Wakaholi B, Mujica Mota RE, Walker AS, Kasirye R, Ssali F, Reid A, Grosskurth H, Babiker AG, Kityo C, Katabira E, Munderi P, Mugyenyi P, Hakim J, Darbyshire J, Gibb DM, Gilks CF; DART Trial Team . Cost effectiveness analysis of clinically driven versus routine laboratory monitoring of antiretroviral therapy in Uganda and Zimbabwe. PLoS One. 2012;7(4):e33672. doi: 10.1371/journal.pone.0033672. 9. Kiwuwa Muyingo S, Walker AS, Oja H, Levin J, Miiro G, Katabira E, Kityo C, Hakim J, Todd J; DART Trial Team . The impact of first year adherence to antiretroviral therapy on long-term clinical and immunological outcomes in the DART trial in Uganda and Zimbabwe . Trop Med Int Health. 2012 May;17(5):584 94. doi: 10.1111/j.1365 3156.2012.02974.x. 10. Carine Ronsmans, Jessica Nakiyingi-Miiro , Gayatri Singh. What is killing pregnant women? A policy brief in “Born, lived and died but counted or not?”, published in January 2012, with an online link of http://www.eldis.org/go/topics/resource guides/hiv and aids&id=59433&type=Document .
5 04/03/13 11. Dunn DT, Goodall RL, Munderi P, Kityo C, Ranopa M, Bacheler L, Van Houtte M, Gilks C, Kaleebu P, Pillay D; DART Virology and Trial Team . Residual activity of two HIV antiretroviral regimens prescribed without virological monitoring. Antimicrob Agents Chemother. 2011 Oct; 55(10): 4575 80. Epub 2011 Jul 18. 12. Jessica Nakiyingi-Miiro , Ivan Kasamba and Billy Mayanja. Is high marital fertility causing Uganda’s population explosion? A policy brief in “HIV and fertility in Africa”, published in September 2011, with an online link of http://www.eldis.org/go/topics/resource guides/hiv and aids&id=59060&type=Document 13. Nakiyingi-Miiro J . The impact of Orphanhood on Education Outcomes in rural Uganda. Are we approaching universal education? University of London: PhD Thesis 2010, 337 pages 14. DART Trial Team . Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomization non-inferiority trial. Lancet, 2010; 375 (9709): 123 131 15. Lyagoba F, Dunn DT, Pillay D, Kityo C, Robertson V, Tugume S, Hakim J, Munderi P, Chirara M, Ndembi N, Goodall RL, Yirrell DL, Burke A, Gilks CF, Kaleebu P; DART Virology and Trial Team . Evolution of drug resistance during 48 weeks of zidovudine/lamivudine/tenofovir in the absence of real-time viral load monitoring. J Acquir Immune Defic Syndr. 2010 Oct;55(2):277 83. 16. Muyingo SK, Walker AS, Reid A, Munderi P, Gibb DM, Ssali F, Levin J, Katabira E, Gilks C, Todd J; DART Trial Team . Patterns of individual and population-level adherence to antiretroviral therapy and risk factors for poor adherence in the first year of the DART trial in Uganda and Zimbabwe. J Acquir Immune Defic Syndr. 2008 Aug 1;48(4):468 75. 17. Shafer, L.A.; Biraro, S.; Nakiyingi-Miiro, J. ; Kamali, A.; Ssematimba, D.; Ouma, J.; Ojwiya, A.; Hughes, P.; van der Paal, L.; Whitworth, J.; Opio, A.; Grosskurth, H. HIV prevalence and incidence are no longer falling in southwest Uganda: evidence from a rural population cohort 1989-2005 AIDS, 2008; 22(13):1641 1649 18. DART trial Team : 24 week safety and tolerability of Nevirapine versus Abacavir in combination with Zidovudine/Lamivudine as first line antiretroviral therapy: A randomised double blind trial (NORA). TMIH 2008; 13 (1): 6 16 19. DART Trial Team : Fixed duration interruptions are inferior to continuous treatment in African adults starting therapy with CD<200 cells/mm 3. AIDS 2008 (2); 22: 237 47 20. Watera C, Todd J, Mutonyi G, Miiro G, Mpendo J, Hughes P, Nakiyingi-Miiro J , Whitworth J, Grosskurth H. Effects of cotrimoxazole on hematologic parameters in HIV-infected adults in a community-based clinic in Entebbe, Uganda. J Acquir Immune Defic Syndr. 2007, 46 (3): 369 371. 21. Biraro S, Morison L, Nakiyingi-Miiro J, Whitworth JAG, Grosskurth H. The role of vertical transmission and Health Care-related factors in HIV infection of children: A community study in rural Uganda. J Acquir Immune Defic Syndr 2007, 44 (2):222 8. 22. Watera C, Todd J, Muwonge R, Whitworth J, Nakiyingi-Miiro J , Brink A, Miiro G, Antvelink L, Kamali A, French N, Mermin J. Feasibility and effectiveness of cotrimoxazole prophylaxis for HIV-1 infected adults attending an HIV/AIDS clinic in Uganda. J Acquir Immune Defic Syndr 2006; 42 : 373 378. 23. Cooke GS, Tosh K, Ramaley PA, Kaleebu P, Zhuang J, Nakiyingi JS , Watera C, Gilks CF, French N, Whitworth JA, Hill AV. A Polymorphism that reduces RANTES expression is associated with protection from death in HIV-seropositive Ugandans with advanced disease. The Journal Infectious Diseases 2006; 194: 666 669. 24. Basia Zaba, Jimmy Whitworth, Milly Marston, Jessica Nakiyingi , Anthony Ruberantwari, Mark Urassa, Raphaeli Issingo, Gabriel Mwaluko, Sian Floyd, Andrew Nyondo, and Amelia Crampin. HIV and Mortality of Mothers and Children: Evidence From Cohort Studies in Uganda, Tanzania and Malawi. Epidemiology 2005; 16 : 275 280.
6 04/03/13 25. Damien de Walque, Jessica Nakiyingi-Miiro , June Busingye, and Jimmy A.Whitworth. Changing association between schooling levels and HIV-1 infection over 11 years in a rural population cohort in south-west Uganda. Tropical Medicine and International Health 2005, 10 : 993 1001 26. Watera C, Nakiyingi J , Miiro G, Muwonge R, Whitworth JAG, Gilks CF and French N. 23-valent pneumococcal polysaccharide vaccine in HIV-infected Ugandan adults: 6 year follow-up of a clinical trial cohort. AIDS 2004, 18 : 1210 1213.
27. Maria A. Quigley, Anatoli Kamali, John Kinsman, Ignatius Kamulegeya, Jessica Nakiyingi-Miiro , Sylvia Kiwuwa, Jane F. Kengeya Kayondo, Lucy M. Carpenter and James A.G. Whitworth. The impact of attending a behavioural intervention on HIV incidence in Masaka, Uganda. AIDS 2004, 18 : 2055 2063. 28. Alison M. Elliot, Henry Luzze, Maria A. Quigley, Jessica S. Nakiyingi , Steven Kyaligonza, Proscovia B. Namujju, Constance Ducar, Jerrold J. Ellner, James A.G. Whitworth, Roy Mugerwa, John L Johnson, and Alphonse Okwera. A Randomised, Double-Blind, Placebo-Controlled Trial of the Use of Prednisolone as an Adjunct to Treatment in HIV-1-Associated Pleural Tuberculosis. JID 2004, 190 : 869 878. 29. Elliott AM, Hodsdon WS, Kyosiimire J, Quigley MA, Nakiyingi JS , Namujju PB, Watera C, French N, Gilks CF, Dockrell HM, and Whitworth JAG. Cytokine responses and progression to active tuberculosis in HIV-1 infected Ugandans: a prospective study. Transactions of the Royal Society of Tropical Medicine and Hygiene 2004, 98 : 660 670. 30. Todd Jim, Carpenter Lucy, Li Xianbin, Nakiyingi Jessica , Gray Ron and Hayes Richard. The effects of alternative study designs on the power of community randomized trials: evidence from three studies of human immunodeficiency virus in East Africa. International Journal of Epidemiology, 2003, 32 : 755 762. 31. Jessica S Nakiyingi , Michael Bracher, James AG Whitworth, Anthony Ruberantwari, June Busingye, Sam M Mbulaiteye, and Basia Zaba. Child survival in relation to mother’s HIV infection and survival: evidence from a Ugandan cohort study. AIDS 2003, 17 : 1827 1834. 32. Kamali A, Quigley M, Nakiyingi J , Kinsman J, Kengeya Kayondo J, Gopal R, Ojwiya A, Hughes P, Carpenter LM and Whitworth JAG. Syndromic management of sexually-transmitted infections and behaviour change interventions on transmission of HIV-1 in rural Uganda: a community randomised trial. Lancet 2003, Vol. 361 : 645 652. 33. Elliott AM, Mawa PA, Joseph S, Namujju PB, Kizza M, Nakiyingi JS , Watera C, Dunne DW and Whitworth JAG. Associations between helminth infection and CD4+ T cell count, viral load and cytokine responses in HIV-1 seropositive Ugandan adults. Transactions of the Royal Society of Tropical Medicine and Hygiene 2003, 97 : 103 108. 34. Alison M Elliott, Jacqueline Kyosiimire J, Maria A Quigley, Jessica Nakiyingi , Christine Watera, Michael Brown, Sarah Joseph, Neil French, Charles F Gilks, and James AG Whitworth. Eosinophilia and progression to active tuberculosis in HIV-1 infected Ugandans. Transactions of the Royal Society of Tropical Medicine and Hygiene 2003, 97 : 477 480. 35. Brown M, Bukusuba J, Hughes P, Nakiyingi J , Watera C, Elliott A, and Whitworth JAG . Screening for intestinal helminth infestation in a semi-urban cohort of HIV-infected people in Uganda: a combination of techniques may enhance diagnostic yield in the absence of multiple stool samples. Tropical Doctor 2003, 33 : 72 76. 36. Whitworth JAG, Mahe C, Mbulaiteye SM, Nakiyingi J , Ruberantwari A, Ojwiya A, and Kamali A. HIV-1 epidemic trends in rural south-west Uganda over a 10-year period. Tropical Medicine and International Health 2002, Vol. 7: 1047 1052. 37. Mbulaiteye SM, Mahe C, Whitworth JAG, Ruberantwari A, Nakiyingi JS , Ojwiya A, and Kamali A. Declining HIV-1 incidence and associated prevalence over 10 years in a rural population in south- west Uganda: a cohort study. Lancet 2002, Vol. 360 : 41 46.
7 04/03/13 38. Lugada ES, Watera C, Nakiyingi J , Elliot A, Brink A, Nanyunja M, French N, Antivelink L, Gilks C, and Whitworth J. Operational assessment of isoniazid prophylaxis in a community AIDS service organisation in Uganda. Int Journal of TB & Lung Disease. 2002, Vol. 6, No. 4: 326 331. 39. Kinsman J, Kamali A, Kanyesigye E, Kamulegeya I, Basajja V, Nakiyingi J , Schenk K, and Whitworth JAG. Quantitative process evaluation of a community-based HIV/AIDS behavioral intervention in rural Uganda. Health Education Research 2002, Vol. 17 no. 2: 253 265. 40. Kaleebu P, French N, Mahe C, Yirrell D, Watera C, Lyagoba F, Nakiyingi J , Rutebemberwa A, Morgan D, Weber J, Gilks C, and Whitworth J. Effect of Human Immunodeficiency Virus (HIV) Type 1 Envelope sub-types A and D on Disease progression in a Large cohort of HIV-1 positive individuals in Uganda. JID 2002, 185 : 1244 1250. 41. Neil French, Katherine Gray, Christine Watera, Jessica Nakiyingi , Eric Lugada, Michael Moore, David Lalloo, James A. G. Whitworth, and Charles F. Gilks . Cryptococcal infection in a cohort of HIV-1 infected Ugandan adults. AIDS 2002, Vol. 16 , No. 2: 1031 1038. 42. Carpenter LM, Kamali A, Payne M, Kiwuwa S, Kintu P, Nakiyingi J , Kinsman J, Nalweyiso N, Quigley MA, Kengeya Kayondo JF, and Whitworth JAG. Independent effects of reported sexually transmitted infections and sexual behavior on HIV-1 prevalence on women, men, and teenagers in rural Uganda. Journal of AIDS 2002, Vol. 29 , No. 2: 174 180 43. H. Luzze, AM Elliott, ML Joloba, ML Odida, J. Oweka Onyee, J. Nakiyingi , M. Quigley, C. Hirsch, RD Mugerwa, A. Okwera, and JL Johnson. Evaluation of suspected tuberculosis pleurisy: clinical and diagnostics findings in HIV-1-positive and HIV-negative adults in Uganda. International Journal of Tuberculosis and Lung Disease 2001, Vol 5. No. 8: 746 753. 44. J. Kinsman, J. Nakiyingi , A. Kamali, and J. Whitworth. Condom awareness and intended use: gender and religious contrasts among school pupils in rural Masaka, Uganda. AIDS CARE 2001, Vol. 13 , No. 2, pages 215 220. 45. J. Kinsman, J. Nakiyingi , A. Kamali, L. Carpenter, M. Quigley, R. Pool and J. Whitworth. Evaluation of a comprehensive school-based AIDS education programme in rural Masaka, Uganda. Health Education Research 2001, Vol. 16 , No. 1, pages 85 100. 46. N. French, J. Nakiyingi , E. Lugada, C. Watera, JAG Whitworth, and CF Gilks. Increasing rates of malarial fever with deteriorating immune status in HIV-1-infected Ugandan adults. AIDS 2001, Vol. 15 , pages 899 906. 47. Basia W. Zaba, Lucy M. Carpenter, J. Ties Boerma, Simon Gregson, Jessica Nakiyingi and Mark Urassa. Adjusting ante-natal clinic data for improved estimates of HIV prevalence among women in sub-Saharan Africa. AIDS 2000, 14: 2741 2750. 48. SM Mbulaiteye, A Ruberantwari, JS Nakiyingi , LM Carpenter, A Kamali and JAG Whitworth. Alcohol and HIV: a study among sexually active adults in rural southwest Uganda. International Journal of Epidemiology 2000; 29 : 911 915. 49. Neil French, Jessica Nakiyingi , Lucy Carpenter, Eric Lugada, Kenneth Moi, Mike Moore, D Antvelink, Daan Mulder, Ed Janoff, Jimmy Whitworth, Charles Gilks. 23-valent Pneumococcal polysaccharide vaccine in HIV-1-infected Ugandan adults: double blind, randomised and placebo controlled trial. Lancet 2000, 355: 2106 2111. 50. Neil French, Andrew Mujugira, Jessica Nakiyingi , Daan W. Mulder, Ed Janoff, Charles Gilks. Immunologic and clinical stages in HIV-1 infected Ugandan adults are comparable and provide no evidence of rapid progression but poor survival with advanced disease. Journal of AIDS 1999, 22: 509 516. 51. Alison M Elliott, Jessica Nakiyingi , Maria A Quigley, Neil French, Charles F Gilks, James AG Whitworth. Inverse association between BCG immunisation and intestinal nematode infestation among HIV-1 positive individuals in Uganda. Lancet 1999, 354: 1000 1001.
8 04/03/13 52. Lucy M. Carpenter, Jessica S. Nakiyingi , Anthony Ruberantwari, Samuel S. Malamba, Anatoli Kamali and James A.G. Whitworth. Estimates of the impact of HIV infection on fertility in a rural Ugandan population cohort. Health Transition Review 1997, Supplement 2 to Volume 7, 113 126. 53. Jessica Sendegeya Nakiyingi . Population composition and Change in an HIV infected Rural Ugandan Community . Australian National University: MSc thesis 1996 54. Anatoli Kamali, Hans Ulrich Wagner, Jessica Nakiyingi , Imelda Sabiiti, Jane F Kengeya Kayondo and Daan W Mulder. Verbal Autopsy as a tool for diagnosing HIV-Related Adult Deaths in Rural Uganda. International Journal of Epidemiology 1996, Vol. 25 , No. 3, pages 679 683. 55. Daan W. Mulder, Andrew J. Nunn, Anatoli Kamali, Jessica Nakiyingi , Hans Ulrich Wagner and Jane F. Kengeya Kayondo. Two year HIV-1 associated mortality in a Ugandan rural population. Lancet 1994, 343 :1021 23.
Conferences and workshops 1. Participant at the Eighth ALPHA/INDEPTH workshop , Kisumu, Kenya, October 3-8, 2011 2. Participant at the Seventh Alpha Network , Mwanza, Tanzania, April 4-8, 2011 . 3. Participant at the Sixth Alpha Network , Entebbe, Uganda, November 21-25, 2010 . 4. Poster exhibition at the International AIDS Conference , Vienna, Austria, July 18-23, 2010 titled [TUPE0503] “Population level effect of parental HIV on child orphan incidence rates 1989 2007, and reversal of this effect after the introduction of Anti Retroviral Therapy (ART) in Uganda”. 5. Participant at the Third Alpha Network , Entebbe, Uganda, November 13-17, 2006 . 6. Participant at the Second Alpha Network , Mtubatuba, Kwazulu Natal, South Africa, June 7-14, 2006 . 7. Participant at the Symposium on Maximising the Education Sector Response to HIV/AIDS , BMA House, Tavistock Square, London, UK , May 17, 2006. 8. Presented a paper at the Orphans and Vulnerable Children Technical Consultation workshop , Washington DC, USA, November 3-5, 2003 titled “Survival of orphans and non orphaned children”. 9. Presented a paper at the 13 th International Conference on AIDS and STDS in Africa (ICASA ), Nairobi, Kenya, September 21-26, 2003 titled [701254] “Impact of Prophylactic Regimens on PPD positive HIV Infected Ugandans”. 10. Presented a paper at the Empirical Evidence of for the Demographic and Socio-Economic Impact of AIDS, Durban, South Africa, March 26-28, 2003 titled “Impact of vertical transmission and parental survival – lessons from the UNICEF meta analysis”. 11. Presented a paper at the UNICEF multi-centre workshop in Impact of HIV on Child mortality, Mwanza, Tanzania, November 28-30, 2002 titled ”Child survival in relation to maternal HIV infection and survival: evidence from a Ugandan Cohort”. 12. Poster presentation at the XIV International AIDS Conference , Barcelona, Spain, July 7-12, 2002 titled [ThPpC2139] “Child survival and mother’s HIV status in a rural Ugandan Cohort”. 13. Poster exhibition at the XIV International AIDS Conference , Barcelona, Spain, July 7-12, 2002 titled [ThPeE6832] “Mobility and HIV infection in a prospective rural Ugandan cohort”. 14. Committee recognition Poster exhibition at the 3rd Symposium on Pneumococci and Pneumococcal Disease , Anchorage, Alaska, May 5-8, 2002 titled [R 08 Board 9] “23 valent Pneumococcal Polysaccharide Vaccine in HIV infected Ugandan Adults: 6 Year follow up of a Clinical Cohort Trial”. 15. Presented a paper at the BSPS meeting on Poverty and Well-being in HIV/AIDS developing countries, London, United Kingdom, January 8, 2002 titled ”Migration, residence, and mobility in relation to HIV 1 prevalence over 10 years in a rural Ugandan Cohort”.
9 04/03/13 16. Poster exhibition at the XIII International AIDS Conference , Durban, South Africa, July 9-14, 2000 titled [MoPeB2304] “Opportunistic Infections and Survival in an HIV positive cohort in Uganda”. 17. Presented a paper in IUSSP Conference on Socio-Demographic Impact of AIDS in Africa Durban, South Africa, February 3-6, 1997 titled ”Household Composition and the HIV epidemic in a rural Ugandan Population”. 18. Presented a paper in The 2nd National AIDS Congress Kampala, Uganda, November 24-27, 1993 titled “HIV 1 infection in a Ugandan town on a Trans African highway: Prevalence and risk factors.”
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Referees 1. Prof. Jonathan Levin 3. Dr. James Whitworth Head of Statistics section Head of International Activities MRC/UVRI Uganda Research Unit The Wellcome Trust P O Box 49 215 Euston Road Entebbe London NW1 2BE Uganda United Kingdom Tel: +256 (0)774 590692 Tel: +44 (0)20 7611 8854 Email: [email protected] Fax: +44 (0)20 7611 7288 Email: [email protected] 2. Mr. Jim Todd Senior Lecturer 4. Prof. Basia Zaba Department of Population Studies Professor in Medical Demography London School of Hygiene & Tropical Department of Population Studies Medicine, Keppel Street London School of Hygiene & Tropical London WC1E 7HT Medicine, Keppel Street Tel: +255 (0)783 388686 London WC1E 7HT Email: [email protected] Email: [email protected]
Signature:
Date: 1st February 2013
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