DOCSLIB.ORG

(12) Patent Application Publication (10) Pub. No.: US 2007/0122492 A1 Behr Et Al

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
(12) Patent Application Publication (10) Pub. No.: US 2007/0122492 A1 Behr Et Al US 2007.0122492A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2007/0122492 A1 Behr et al. (43) Pub. Date: May 31, 2007 (54) PLANT EXTRACTS AND Publication Classification DERMATOLOGICAL USES THEREOF (51) Int. Cl. A6IR 36/45 (2006.01) A6IR 36/53 (2006.01) A 6LX 36/899 (2006.01) (76) Inventors: Stephen Behr, Outremont (CA); A6IR 36/8962 (2006.01) Philippe Duret, Quebec (CA); Nathalie A6IR 36/906 (2006.01) Gendron, Neuville (CA); Johane A6IR 36/48 (2006.01) Guay, St-Augustin de Desmaures (CA); A6IR 36/8 (2006.01) Bernard Lavallee, Ste. Foy (CA); A6IR 36/3 (2006.01) Brigitte Page, Quebec (CA) A6IR 36/23 (2006.01) (52) U.S. Cl. ......................... 424/725; 424/750; 424/754; 424/732; 424/760; 424/770; 424/757; 424/756; 424/745 Correspondence Address: HELLEREHRMAN LLP (57) ABSTRACT 275 MODLEFIELD ROAD MENLO PARK, CA 94025-3506 (US) The present invention provides for plant extracts and der matological formulations comprising one or more plant extracts that are capable of inhibiting one or more extracel lular proteases selected from the group of matrix metallo protease-1 (MMP-1), matrix metalloprotease-2 (MMP-2), (21) Appl. No.: 10/533,025 matrix metalloprotease-3 (MMP-3), matrix metallopro tease-9 (MMP-9) and human leukocyte elastase (HLE). The present invention further provides for a rapid method for screening plant extracts to identify those having the above (22) PCT Fed: Nov. 18, 2004 activity that are suitable for incorporation into the derma tological formulations of the invention. The invention also provides for the use of the plant extracts as dermatological agents Suitable for the treatment or prevention of various (86) PCT No.: dermatological conditions, including wrinkling or sagging of the skin, irradiation induced skin and/or hair damage, S 371(c)(1), deepening of skin lines, elastotic changes in the skin, as well (2), (4) Date: Nov. 20, 2006 as for the routine care of the skin, hair and/or nails. Patent Application Publication May 31, 2007 Sheet 1 of 9 US 2007/O122492 A1 FIGURE 1 Potential Plant Optional Pre-Harvest Treatment Harvest Solid Sl Optional Storage Treatment us an X is 88 as a Contact Solid S1 with Solvent A Extraction Process I Separate Extract A m from Solid Matter S2 Potential Extract A Extraction Process II Separate Extract B from Solid Matter S3 Contact Solid S3 with Solvent C Extraction Process III Separate Extract C from Solid Matter S4 Solid S4 Patent Application Publication May 31, 2007 Sheet 2 of 9 US 2007/0122492 A1 FIGURE 2 Potential Extract Optional Separation Procedure(s) Potential Extract Test Aliquots against OC O. O. Extracellular Proteases Does Extract demonstrate inhibitory Potential Extract is an Inconclusive Extract of the activity against one or more extracellular Invention proteases? Potential Extract is not an Extract of the Invention Plant remains a Potential Plant Entire Procedure may be repeated on Potential Plant under varied conditions Patent Application Publication May 31, 2007 Sheet 3 of 9 US 2007/0122492 A1 FIGURE 3 One or More Plants of the Invention Optional Pre-Harvest Treatment Harvest Solid Sl Optional Storage Treatment Extraction Process I, II or II. Process may be sequentially repeated Purification Procedure(s) Quality Control Extract Demonstrating Inhibitory Activity Against One or More Extracellular Proteases Prepare Formulation for Use Patent Application Publication May 31, 2007 Sheet 4 of 9 US 2007/0122492 A1 FIGURE 4 Patent Application Publication May 31, 2007 Sheet 5 of 9 US 2007/O122492 A1 FIGURE 5 Patent Application Publication May 31, 2007 Sheet 6 of 9 US 2007/O122492 A1 FIGURE 6 Dried powdered material Analytical Scale: 2 - 10 g Large scale: 2-3 kg Analytical scale: procedure 1 Large scale: procedure 2 Centrifugation EtOHIMeoH extract EtOHIwater extract Concentration under reduce pressure EtOHIMeOH extract Dilution with 10-5% water Partition with hexane Extract B Hexane extract C 1) Concentration Procedure 2) Solubilization EtOH water 20/80 viv EtOHIMeOh:8515 why 3) Partition with Ethyl acetate 2x100ml protocola) SOHNWater 85/15 wiv 2x100ml (protocol b) Blender (2 x 10 min) Room temperature Procedure 2: Evaporation to dryness OHIMech:85/15 viv (protocola) EtOHWatar: 85/15 yN Aqueous extract E ACOEt extract F maceration(protocol b) percolation A. Room terrperattire Patent Application Publication May 31, 2007 Sheet 7 of 9 US 2007/0122492 A1 — Melilotus alba -e-keratinocytes -O-Fibroblasts 80 6 O -e-keratinocytes -O- Fibroblasts FIGURE 7 Patent Application Publication May 31, 2007 Sheet 8 of 9 US 2007/0122492 A1 1009wÐ (OS:OS)OZH:ng»Dow (08:0Z)OZH:ngXpow (0:001)ozH:ng»Dow FIGURE 8 Patent Application Publication May 31, 2007 Sheet 9 of 9 US 2007/0122492 A1 a 3S. SE. 5E. 5E 5E 5E saE 9 EN S.E on s in o un o o g 2 2 3 ac U nO y ON Ms w wrd R.o N ra a.c -- O cs d c ES o O : E isd C ro cn cs 5 S.E <: S5 s Cd o ?u Vs t cyL c) - Q C > d- ? s - O o 3 U O U g s s s o . --a S.d — 3 is E is FIGURE 9 US 2007/01 22492 A1 May 31, 2007 PLANT EXTRACTS AND DERMATOLOGICAL activity of MMP-1, -2, -3 and -9 in the skin has also been USES THEREOF shown to occur in response to extrinsic factors such as UV exposure (see U.S. Pat. No. 5,837.224). The ageing process FIELD OF INVENTION (both chronological and photo-induced) involves the increased breakdown various components of the ECM in the 0001. The invention pertains to the field of dermatology, skin, notably collagen, elastin and fibronectin. Enhanced specifically within the field of dermatological preparations expression of collagenase (MMP-1) and stromelysin-1 comprising plant extracts. (MMP-3) has been described as playing a central role in connective tissue breakdown in the skin (Brenneisen, et al., BACKGROUND OF THE INVENTION (2002) Ann. N.Y. Acad. Sci., 973:31-43). Similarly, increased expression of serine elastase in hairless mouse 0002 The skin is the most environmentally-stressed models of chronological and photo-ageing was shown to organ in mammals, particularly in humans. Not only is the skin Subjected to germs, toxic chemicals and hostile envi result in increased fibronectin degradation (Labat-Robert, et ronments, it is the only organ directly exposed to ultraviolet al., (2000) J Photochem. Photobiol. B., 57:113-118). light (UV). In addition, the vitality of this organ is a 0005 Elastic fibers are essential extracellular matrix consequence of genetic processes, which over time, lead to macromolecules comprising an elastin core surrounded by a a decrease in the functionality of the skin. Hence, a variety mantle of fibrillin-rich microfibrils. These fibers endow of dermatological conditions may occur as a result of connective tissues such as blood vessels, lungs and skin with ongoing intrinsic factors (for example, chronological age the critical properties of elasticity and resilience (see review ing, disease and allergies) and/or exposure to a number of of elastic fibers by Kielty C M et al: J Cell Sci (2002) extrinsic factors (such as infection, trauma, radiation, toxins 115:2817-2828). Exposure to the sun is known to cause and steroid use). Skin is a highly organized structure con disorganization of elastin in the skin known as "elastosis.” sisting of two principal parts. The outer thinner part, the which is also a hallmark of skin-ageing. Neutrophil elastase epidermis or cuticle, is organised into four or five cell layers has been implicated in elastosis, for example, when com depending on its location. These layers are the stratum pared to normal mice, mice that are deficient in neutrophil corneum, stratum lucidem (usually only present where the elastase are unaffected by exposure to UVB. In addition, an skin is thickened), stratum granulosum, stratum spinosum increase in elastase activity has been observed in the skin and stratum basale. The inner, thicker part of the skin, the following chronic UVB irradiation (Tsukahara Ketal Biol dermis or true skin, is composed of a papillary layer above Pharm Bull 2001:24(9):998-1003). Both a synthetic inhibi and a reticular layer below. The dermis also comprises blood tor of fibroblast elastase and an extract of Sanguisorba vessels, nerves, hair follicles and Sweat glands. The layer officinalis L. inhibited wrinkle formation and maintained below the dermis, the hypodermis, comprises mainly loose skin elasticity in the rat (Tsukahara Ketal Biol Pharm Bull connective tissue and adipose cells and may be considered 2001:24(9):998-1003). part of the skin in that it functions to anchor the epidermis/ 0006 MMPs also play a role in the loss of elastic fibers dermis to the underlying bone and muscle. The hypodermis in skin. Tissue loss during ageing and age-dependent also supplies the dermis with blood vessels and nerves. pathologies are the result of a disturbed regulation of pro 0003. The cells of the skin, like many tissues, are gen teolytic activities in which elastase-type endopeptidases, erally in contact with a network of large extracellular especially MMP-2 and -9, are overactivated (Isnard Netal: macromolecules that occupy the spaces in a tissue between Biomed Pharmacother. 2002 July:56(5):258-64). In addi the component cells and between adjacent tissues. This tion, gelatinase B (MMP-9) has been shown to degrade extracellular matrix (ECM) functions as a scaffolding on fibrillin in human skin tissue sections (Berton Aetal, Matrix which the cells and tissue are supported and is involved Biol 2000:19(2): 139-148). actively in regulating interaction of the cells that contact it.
Load more

Recommended publications
  • Pima County Plant List (2020) Common Name Exotic? Source
    Pima County Plant List (2020) Common Name Exotic? Source McLaughlin, S. (1992); Van Abies concolor var. concolor White fir Devender, T. R. (2005) McLaughlin, S. (1992); Van Abies lasiocarpa var. arizonica Corkbark fir Devender, T. R. (2005) Abronia villosa Hariy sand verbena McLaughlin, S. (1992) McLaughlin, S. (1992); Van Abutilon abutiloides Shrubby Indian mallow Devender, T. R. (2005) Abutilon berlandieri Berlandier Indian mallow McLaughlin, S. (1992) Abutilon incanum Indian mallow McLaughlin, S. (1992) McLaughlin, S. (1992); Van Abutilon malacum Yellow Indian mallow Devender, T. R. (2005) Abutilon mollicomum Sonoran Indian mallow McLaughlin, S. (1992) Abutilon palmeri Palmer Indian mallow McLaughlin, S. (1992) Abutilon parishii Pima Indian mallow McLaughlin, S. (1992) McLaughlin, S. (1992); UA Abutilon parvulum Dwarf Indian mallow Herbarium; ASU Vascular Plant Herbarium Abutilon pringlei McLaughlin, S. (1992) McLaughlin, S. (1992); UA Abutilon reventum Yellow flower Indian mallow Herbarium; ASU Vascular Plant Herbarium McLaughlin, S. (1992); Van Acacia angustissima Whiteball acacia Devender, T. R. (2005); DBGH McLaughlin, S. (1992); Van Acacia constricta Whitethorn acacia Devender, T. R. (2005) McLaughlin, S. (1992); Van Acacia greggii Catclaw acacia Devender, T. R. (2005) Acacia millefolia Santa Rita acacia McLaughlin, S. (1992) McLaughlin, S. (1992); Van Acacia neovernicosa Chihuahuan whitethorn acacia Devender, T. R. (2005) McLaughlin, S. (1992); UA Acalypha lindheimeri Shrubby copperleaf Herbarium Acalypha neomexicana New Mexico copperleaf McLaughlin, S. (1992); DBGH Acalypha ostryaefolia McLaughlin, S. (1992) Acalypha pringlei McLaughlin, S. (1992) Acamptopappus McLaughlin, S. (1992); UA Rayless goldenhead sphaerocephalus Herbarium Acer glabrum Douglas maple McLaughlin, S. (1992); DBGH Acer grandidentatum Sugar maple McLaughlin, S. (1992); DBGH Acer negundo Ashleaf maple McLaughlin, S.
    [Show full text]
  • Appendix F3 Rare Plant Survey Report
    Appendix F3 Rare Plant Survey Report Draft CADIZ VALLEY WATER CONSERVATION, RECOVERY, AND STORAGE PROJECT Rare Plant Survey Report Prepared for May 2011 Santa Margarita Water District Draft CADIZ VALLEY WATER CONSERVATION, RECOVERY, AND STORAGE PROJECT Rare Plant Survey Report Prepared for May 2011 Santa Margarita Water District 626 Wilshire Boulevard Suite 1100 Los Angeles, CA 90017 213.599.4300 www.esassoc.com Oakland Olympia Petaluma Portland Sacramento San Diego San Francisco Seattle Tampa Woodland Hills D210324 TABLE OF CONTENTS Cadiz Valley Water Conservation, Recovery, and Storage Project: Rare Plant Survey Report Page Summary ............................................................................................................................... 1 Introduction ..........................................................................................................................2 Objective .......................................................................................................................... 2 Project Location and Description .....................................................................................2 Setting ................................................................................................................................... 5 Climate ............................................................................................................................. 5 Topography and Soils ......................................................................................................5
    [Show full text]
  • Vascular Plant and Vertebrate Inventory of Chiricahua National Monument
    In Cooperation with the University of Arizona, School of Natural Resources Vascular Plant and Vertebrate Inventory of Chiricahua National Monument Open-File Report 2008-1023 U.S. Department of the Interior U.S. Geological Survey National Park Service This page left intentionally blank. In cooperation with the University of Arizona, School of Natural Resources Vascular Plant and Vertebrate Inventory of Chiricahua National Monument By Brian F. Powell, Cecilia A. Schmidt, William L. Halvorson, and Pamela Anning Open-File Report 2008-1023 U.S. Geological Survey Southwest Biological Science Center Sonoran Desert Research Station University of Arizona U.S. Department of the Interior School of Natural Resources U.S. Geological Survey 125 Biological Sciences East National Park Service Tucson, Arizona 85721 U.S. Department of the Interior DIRK KEMPTHORNE, Secretary U.S. Geological Survey Mark Myers, Director U.S. Geological Survey, Reston, Virginia: 2008 For product and ordering information: World Wide Web: http://www.usgs.gov/pubprod Telephone: 1-888-ASK-USGS For more information on the USGS-the Federal source for science about the Earth, its natural and living resources, natural hazards, and the environment: World Wide Web:http://www.usgs.gov Telephone: 1-888-ASK-USGS Suggested Citation Powell, B.F., Schmidt, C.A., Halvorson, W.L., and Anning, Pamela, 2008, Vascular plant and vertebrate inventory of Chiricahua National Monument: U.S. Geological Survey Open-File Report 2008-1023, 104 p. [http://pubs.usgs.gov/of/2008/1023/]. Cover photo: Chiricahua National Monument. Photograph by National Park Service. Note: This report supersedes Schmidt et al. (2005). Any use of trade, product, or firm names is for descriptive purposes only and does not imply endorsement by the U.S.
    [Show full text]
  • Vascular Plant and Vertebrate Inventory of Montezuma Castle National Monument Vascular Plant and Vertebrate Inventory of Montezuma Castle National Monument
    Schmidt, Drost, Halvorson In Cooperation with the University of Arizona, School of Natural Resources Vascular Plant and Vertebrate Inventory of Montezuma Castle National Monument Vascular Plant and Vertebrate Inventory of Montezuma Castle National Monument Plant and Vertebrate Vascular U.S. Geological Survey Southwest Biological Science Center 2255 N. Gemini Drive Flagstaff, AZ 86001 Open-File Report 2006-1163 Southwest Biological Science Center Open-File Report 2006-1163 November 2006 U.S. Department of the Interior U.S. Geological Survey National Park Service In cooperation with the University of Arizona, School of Natural Resources Vascular Plant and Vertebrate Inventory of Montezuma Castle National Monument By Cecilia A. Schmidt, Charles A. Drost, and William L. Halvorson Open-File Report 2006-1163 November, 2006 USGS Southwest Biological Science Center Sonoran Desert Research Station University of Arizona U.S. Department of the Interior School of Natural Resources U.S. Geological Survey 125 Biological Sciences East National Park Service Tucson, Arizona 85721 U.S. Department of the Interior Dirk Kempthorne, Secretary U.S. Geological Survey Mark Myers, Director U.S. Geological Survey, Reston, Virginia: 2006 Note: This document contains information of a preliminary nature and was prepared primarily for internal use in the U.S. Geological Survey. This information is NOT intended for use in open literature prior to publication by the investigators named unless permission is obtained in writing from the investigators named and from the Station Leader. Suggested Citation Schmidt, C. A., C. A. Drost, and W. L. Halvorson 2006. Vascular Plant and Vertebrate Inventory of Montezuma Castle National Monument. USGS Open-File Report 2006-1163.
    [Show full text]
  • USOS Y POSIBILIDAD DE CULTIVO DE LA SAYA (Amoreuxia Spp.) EN
    USOS Y POSIBILIDAD DE CULTIVO DE LA SAYA (Amoreuxia spp.) EN EL NOROESTE DE MÉXICO USES AND POSSIBILITY OF CULTIVATION OF SAYA (Amoreuxia spp.) IN THE NORTHWEST OF MEXICO Celaya-Michel, H.1*; Valdez-Domínguez, R.D.1; Sosa-Castañeda, J.1; Morales-Munguía, J.C.1; Barrera-Silva, M.A.1; Rueda-Puente, E.O.1 1Universidad de Sonora. Departamento de Agricultura y Ganadería. Carretera Bahía de Kino km 18.5, Hermosillo, Sonora, México. *Autor de correspondencia: [email protected] ABSTRACT Saya (Amoreuxia spp.) was a plant consumed by ethnic groups in the past and by the first colonizers, but even today, in regions of the northwest of Mexico it is still consumed. Two species of the genus Amoreuxia are listed in NOM-O59- SEMARNAT-2010: A. palmatifida and A. wrightii. Despite the recognition for several decades of its potential as a food, as fodder for fauna or domestic livestock, its importance in the functioning of the ecosystem, its medicinal use and possible ornamental use; Many aspects of propagation, growth and productivity under the agronomic management of the saya are unknown. In this work the results of growth and productivity of A. palmatifida are shown under experimental botanical garden soil with drip irrigation. Extrapolating our results to agricultural conditions, we estimate a productivity of 20,000 tuberous saya roots per hectare and 3,100,000 seeds per hectare. With these results we can think that it is viable germination and production strategies in agricultural plots with drip irrigation, previous obtaining of the corresponding permits on the SEMARNAT, which could allow obtaining propagules, both from tuberous roots and saya seeds, to be used in the ecological restoration of degraded lands or for harvesting programs as a new crop.
    [Show full text]
  • IP Athos Renewable Energy Project, Plan of Development, Appendix D.2
    APPENDIX D.2 Plant Survey Memorandum Athos Memo Report To: Aspen Environmental Group From: Lehong Chow, Ironwood Consulting, Inc. Date: April 3, 2019 Re: Athos Supplemental Spring 2019 Botanical Surveys This memo report presents the methods and results for supplemental botanical surveys conducted for the Athos Solar Energy Project in March 2019 and supplements the Biological Resources Technical Report (BRTR; Ironwood 2019) which reported on field surveys conducted in 2018. BACKGROUND Botanical surveys were previously conducted in the spring and fall of 2018 for the entirety of the project site for the Athos Solar Energy Project (Athos). However, due to insufficient rain, many plant species did not germinate for proper identification during 2018 spring surveys. Fall surveys in 2018 were conducted only on a reconnaissance-level due to low levels of rain. Regional winter rainfall from the two nearest weather stations showed rainfall averaging at 0.1 inches during botanical surveys conducted in 2018 (Ironwood, 2019). In addition, gen-tie alignments have changed slightly and alternatives, access roads and spur roads have been added. PURPOSE The purpose of this survey was to survey all new additions and re-survey areas of interest including public lands (limited to portions of the gen-tie segments), parcels supporting native vegetation and habitat, and windblown sandy areas where sensitive plant species may occur. The private land parcels in current or former agricultural use were not surveyed (parcel groups A, B, C, E, and part of G). METHODS Survey Areas: The area surveyed for biological resources included the entirety of gen-tie routes (including alternates), spur roads, access roads on public land, parcels supporting native vegetation (parcel groups D and F), and areas covered by windblown sand where sensitive species may occur (portion of parcel group G).
    [Show full text]
  • Chromosome Numbers in Compositae, XII: Heliantheae
    SMITHSONIAN CONTRIBUTIONS TO BOTANY 0 NCTMBER 52 Chromosome Numbers in Compositae, XII: Heliantheae Harold Robinson, A. Michael Powell, Robert M. King, andJames F. Weedin SMITHSONIAN INSTITUTION PRESS City of Washington 1981 ABSTRACT Robinson, Harold, A. Michael Powell, Robert M. King, and James F. Weedin. Chromosome Numbers in Compositae, XII: Heliantheae. Smithsonian Contri- butions to Botany, number 52, 28 pages, 3 tables, 1981.-Chromosome reports are provided for 145 populations, including first reports for 33 species and three genera, Garcilassa, Riencourtia, and Helianthopsis. Chromosome numbers are arranged according to Robinson’s recently broadened concept of the Heliantheae, with citations for 212 of the ca. 265 genera and 32 of the 35 subtribes. Diverse elements, including the Ambrosieae, typical Heliantheae, most Helenieae, the Tegeteae, and genera such as Arnica from the Senecioneae, are seen to share a specialized cytological history involving polyploid ancestry. The authors disagree with one another regarding the point at which such polyploidy occurred and on whether subtribes lacking higher numbers, such as the Galinsoginae, share the polyploid ancestry. Numerous examples of aneuploid decrease, secondary polyploidy, and some secondary aneuploid decreases are cited. The Marshalliinae are considered remote from other subtribes and close to the Inuleae. Evidence from related tribes favors an ultimate base of X = 10 for the Heliantheae and at least the subfamily As teroideae. OFFICIALPUBLICATION DATE is handstamped in a limited number of initial copies and is recorded in the Institution’s annual report, Smithsonian Year. SERIESCOVER DESIGN: Leaf clearing from the katsura tree Cercidiphyllumjaponicum Siebold and Zuccarini. Library of Congress Cataloging in Publication Data Main entry under title: Chromosome numbers in Compositae, XII.
    [Show full text]
  • (12) Patent Application Publication (10) Pub. No.: US 2009/0263516 A1 CYR (43) Pub
    US 20090263516A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2009/0263516 A1 CYR (43) Pub. Date: Oct. 22, 2009 (54) PLANT EXTRACT COMPOSITION AND Publication Classification THEIR USE TO MODULATE CELLULAR (51) Int. Cl. ACTIVITY A636/8962 (2006.01) A636/00 (2006.01) (75) Inventor: Benoit CYR, St. Augustin de A6IP35/00 (2006.01) Desmaures (CA) CI2N 5/06 (2006.01) Correspondence Address: A6IR 36/3 (2006.01) SHEPPARD, MULLIN, RICHTER & HAMPTON A 6LX 36/899 (2006.01) LLP (52) U.S. Cl. ......... 424/754; 424/725; 435/375; 424/774; 990 Marsh Road 424/779; 424/755; 424/750; 424/777 Menlo Park, CA 94025 (US) (57) ABSTRACT (73) Assignee: Biopharmacopae Design Extracts from plant material, or semi-purified/purified mol International Inc., Saint-Foy (CA) ecules or compounds prepared from the extracts that demon strate the ability to modulate one or more cellular activities (21) Appl. No.: 12/263,114 are provided. The extracts are capable of slowing down, inhibiting or preventing cell migration, for example, the (22) Filed: Oct. 31, 2008 migration of endothelial cells or neoplastic cells and thus, the use of the extracts to slow down, inhibit or prevent abnormal Related U.S. Application Data cell migration in an animal is also provided. Methods of selecting and preparing the plant extracts and methods of (63) Continuation of application No. 10/526,387, filed on screening the extracts to determine their ability to modulate Oct. 6, 2005, now abandoned, filed as application No. one or more cellular activity are described. The purification or PCT/CA03/01284 on Sep.
    [Show full text]
  • Anza-Borrego Desert State Park Bibliography Compiled and Edited by Jim Dice
    Steele/Burnand Anza-Borrego Desert Research Center University of California, Irvine UCI – NATURE and UC Natural Reserve System California State Parks – Colorado Desert District Anza-Borrego Desert State Park & Anza-Borrego Foundation Anza-Borrego Desert State Park Bibliography Compiled and Edited by Jim Dice (revised 1/31/2019) A gaggle of geneticists in Borrego Palm Canyon – 1975. (L-R, Dr. Theodosius Dobzhansky, Dr. Steve Bryant, Dr. Richard Lewontin, Dr. Steve Jones, Dr. TimEDITOR’S Prout. Photo NOTE by Dr. John Moore, courtesy of Steve Jones) Editor’s Note The publications cited in this volume specifically mention and/or discuss Anza-Borrego Desert State Park, locations and/or features known to occur within the present-day boundaries of Anza-Borrego Desert State Park, biological, geological, paleontological or anthropological specimens collected from localities within the present-day boundaries of Anza-Borrego Desert State Park, or events that have occurred within those same boundaries. This compendium is not now, nor will it ever be complete (barring, of course, the end of the Earth or the Park). Many, many people have helped to corral the references contained herein (see below). Any errors of omission and comission are the fault of the editor – who would be grateful to have such errors and omissions pointed out! [[email protected]] ACKNOWLEDGEMENTS As mentioned above, many many people have contributed to building this database of knowledge about Anza-Borrego Desert State Park. A quantum leap was taken somewhere in 2016-17 when Kevin Browne introduced me to Google Scholar – and we were off to the races. Elaine Tulving deserves a special mention for her assistance in dealing with formatting issues, keeping printers working, filing hard copies, ignoring occasional foul language – occasionally falling prey to it herself, and occasionally livening things up with an exclamation of “oh come on now, you just made that word up!” Bob Theriault assisted in many ways and now has a lifetime job, if he wants it, entering these references into Zotero.
    [Show full text]
  • Pdf Clickbook Booklet
    119 Rubia Galium stellatum star-flowered bedstraw 1 120 Simmo Simmondsia chinensis jojoba 4 2 Flora of Uppermost Box Canyon Road near I-10, Riverside County 121 Solan Datura wrightii sacred datura 1 # Famil Scientific Name (*)Common Name #V #iNat 122 Solan Lycium andersonii Anderson's boxthorn ~x Eudicots 123 Solan Nicotiana obtusifolia desert tobacco 1 1 Apocy Asclepias subulata rush milkweed 1 1 124 Solan Physalis crassifolia thick-leaved ground cherry 1 1 2 Aster Ambrosia dumosa burroweed 14 125 Visca Phoradendron californicum desert mistletoe 2 2 3 Aster Ambrosia salsola cheesebush 2 9 126 Zygop Fagonia laevis California fagonia 3 9 4 Aster Atrichoseris platyphylla gravel-ghost 3 2 127 Zygop Kallstroemia californica California caltrop 2 5 Aster Bahiopsis parishii Parish's goldeneye 1 128 Zygop Larrea tridentata creosote bush 16 6 Aster Bebbia juncea var. aspera sweetbush 3 129 Zygop Tribulus terrestris *puncture-vine 1 7 Aster Brickellia incana woolly brickellia 5 Monocots 8 Aster Chaenactis carphoclinia var. carphoclinia pebble pincushion 1 130 Poace Bouteloua aristidoides var. aristidoides needle grama 2 9 Aster Chaenactis fremontii Fremont pincushion 1 131 Poace Bouteloua barbata var. barbata six-weeks grama 1 10 Aster Encelia farinosa brittlebush 11 132 Poace Schismus barbatus *Mediterranean schismus 1 5 11 Aster Malacothrix glabrata desert dandelion 2 http://tchester.org/plants/floras/desert/upper_box_canyon_road_near_I10.html Last update: 20 January 2020 12 Aster Monoptilon bellidiforme desert star 1 1 13 Aster Monoptilon bellioides desert star 1 1 14 Aster Palafoxia arida var. arida Spanish needle 2 15 Aster Pectis papposa var. papposa chinch-weed 3 1 16 Aster Perityle emoryi Emory's rock-daisy 3 17 Aster Peucephyllum schottii pygmy-cedar 1 2 18 Aster Pleurocoronis pluriseta arrow-leaf 1 19 Aster Rafinesquia neomexicana desert chicory 1 20 Aster Senecio mohavensis Mojave ragwort 3 21 Aster Stephanomeria pauciflora wire-lettuce 1 22 Aster Trichoptilium incisum yellow-head 2 2 23 Aster Trixis californica var.
    [Show full text]
  • There's a New Fly in Town
    Master Gardeners Association of BC Newsletter Volume 23, No. 3 www.bcmastergardeners.org September 2010 There's a New Fly in Town There’s a new species of vinegar fly (small fruit fly) drosophila attacks ripe, ready-to-harvest fruit, ren- in British Columbia that threatens to destroy millions dering it unsaleable and inedible. And just to make of dollars worth of fruit things really interesting, unless local populations researchers at Oregon can be quickly identified State University believe and suppressed before that this prolific insect they get out of hand. can produce as many as 10 to 13 generations in Known as the spotted a single season. That’s wing drosophila (Dro- not only a lot of fruit flies, sophila suzukii), this it’s a lot of opportunity for Asian native was un- the species to develop known in North America immunity to any pesti- until it was discovered cides used to control it. in coastal California in 2008. It has since The spotted wing dro- spread north along the sophila looks pretty much coast with breathtaking like all other vinegar flies speed, targeting a wide except that the males variety of thin-skinned have a grey-black spot on fruits such as blackberries, blueberries, cherries, the end of each wing and the females have a saw- grapes, pears, nectarines, peaches, plums, raspber- like ovipositor (an appendage they use to cut into fruit ries, and strawberries. In 2009, it was credited with so that they can lay their eggs). Note that females destroying more than 30 percent of California’s cherry don’t have spots on their wings, only males (see harvest.
    [Show full text]
  • 17 December 2014 FIELD CHECKLIST of the VASCULAR
    17 December 2014 TAXACEAE (Yew Family) __ Taxus canadensis Canada Yew FIELD CHECKLIST OF THE VASCULAR PLANTS OF JOKERS HILL King Township, Regional Municipality of York PINACEAE (Pine Family) C.S Blaney and P.M. Kotanen* __ Larix laricina Tamarack *Correspondence author: __ Picea glauca White Spruce Department of Ecology & Evolutionary Biology __ Pinus strobus White Pine University of Toronto at Mississauga __ Pinus sylvestris Scots Pine 3359 Mississauga Road North __ Tsuga canadensis Eastern Hemlock Mississauga, ON Canada CUPRESSACEAE (Cypress Family) e-mail: [email protected] __ Juniperus communis Common Juniper __ Juniperus virginiana Eastern Red Cedar The following list is based on observations and collections by the authors between 1997 and 1999, __ Thuja occidentalis Eastern White Cedar with later additions by numerous observers. It includes all species known to be growing outside of cultivation within the Jokers Hill property. Also listed are native species found in land adjacent to the TYPHACEAE (Cat-tail Family) Jokers Hill property, but not yet found on the site (scientific name preceded by "*" - 13 species). A __ Typha angustifolia Narrow-leaved Cat-tail total of 631 taxa (species and hybrids) are listed; 450 taxa are considered native to Jokers Hill (those __ Typha latifolia Common Cat-tail listed in bold typeface) and 181 are considered non-native (listed in regular typeface). Determining native versus non-native status required a few rather arbitrary judgements. SPARGANIACEAE (Bur-reed Family) __ Sparganium chlorocarpum Green Bur-reed Several people assisted in the preparation of this list. P. Ball of the University of Toronto at Mississauga and A.
    [Show full text]