Product Datasheet LAT2 Antibody Orb99201

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Product Datasheet LAT2 Antibody Orb99201

Biorbyt Ltd. Biorbyt LLC. 5 Orwell Furlong, Cowley Road, Cambridge 1100 Corporate Square Drive, Helix Center, Suite 221 CB4 0WY, United Kingdom St Louis, MO 63132, United States Email: [email protected] Email: [email protected] Phone: +44 (0)1223 859 353 | Fax: +44 (0)1223 280 240 Phone: +1 (415) 906 5211 | Fax: +1 (415) 651 8558 Product Datasheet LAT2 antibody orb99201 Description Rabbit Polyclonal to LAT2. LAT2 (Linker for Activation of T Cells Family, Member 2), also known as LAB or NTAL , is a protein that in humans is encoded by the LAT2 gene. By genomic sequence analysis, Doyle et al. (2000) mapped the WBSCR5 gene to chromosome 7q11.23. They noted that the flanking genes are highly conserved between mouse and human. By immunoprecipitation and immunoblot analysis, Brdicka et al. (2002) found that NTAL associated with GRB2, SOS1, and GAB1 after B-cell receptor activation. Janssen et al. (2003) determined Western blot analysis of that phosphorylation of LAB is likely mediated by SYK upon B-cell Lane receptor stimulation. Binding analysis indicated associations with 1: Recombinant Human GRB2, and, indirectly, with PLCG1 and PLCG2. LAT2 Protein 10ng, Lane 2: Species/Host Rabbit Recombinant Human LAT2 Protein Reactivity Human 5ng, Lane 3: Recombinant Human LAT2 Protein 2.5ng, Lane Conjugation Unconjugated 4: Recombinant Human LAT2 Tested Applications WB Protein 1.25ng using LAT2 antibody Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human LAT2(34-48aa KRSEKIYQQRSLRED). Target LAT2. Human.No cross reactivity with other proteins. Form/Appearance Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Concentration 500μg/ml Storage Store at -20°C for one year.After reconstitution, at 4°C. for one month. It can also be aliquotted and stored frozen at -20°C. for a longer time. Avoid repeated freezing and thawing. Note For research use only. Isotype Rabbit IgG Clonality Polyclonal Purity Immunogen affinity purified. Uniprot ID Q9GZY6 Expiration Date 12 months from date of receipt. Application Notes Experiment Notes: Add 0.2ml of distilled water will yield a concentration of 500ug/ml..

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LAT2 Monoclonal Antibody, Clone NAP-07 (PE)
LAT2 monoclonal antibody, clone NAP-07 (PE) Catalog # : MAB4522 規格 : [ 100 ug ] List All Specification Application Image Product Mouse monoclonal antibody raised against partial recombinant LAT2. Western Blot Description: Immunocytochemistry Immunogen: Recombinant protein corresponding to partial human LAT2. Immunoprecipitation Flow Cytometry Host: Mouse Theoretical MW 25-30 (kDa): Reactivity: Human, Mouse Specificity: This antibody reacts with Non-T cell activation linker (NTAL), also known as LAB (linker of activated B cells), a 25-30 KDa transmembrane adaptor protein present in membrane microdomains (rafts) of B lymphocytes, NK cells and myeloid cells. Form: Liquid Conjugation: PE Concentration: 0.1 mg/mL Isotype: IgG1 Recommend Flow Cytometry (1:30) Usage: The optimal working dilution should be determined by the end user. Storage Buffer: In PBS (0.2% BSA, 0.09% sodium azide) Storage Store in the dark at 4°C. Do not freeze. Instruction: Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing. Note: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. Datasheet: Download Publication Reference 1. Topography of signaling molecules as detected by electron microscopy on plasma membrane sheets isolated from non-adherent mast cells. Lebduska P, Korb J, Tumova M, Heneberg P, Draber P.J Immunol Methods. 2007 Dec 1;328(1-2):139-51. Epub 2007 Sep 18. 2. Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL. Volna P, Lebduska P, Draberova L, Simova S, Heneberg P, Boubelik M, Bugajev V, Malissen B, Wilson BS, Horejsi V, Malissen M, Draber P.J Exp Med.
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