FOLR2 Antibody Cat. No.: 61-763

FOLR2 Antibody

Western blot analysis of lysates from MDA-MB-453 cell line, Western blot analysis of lysate from human placenta human placenta tissue lysate (from left to right), using FOLR2 tissue lysate, using FOLR2 Antibody at 1:1000. Antibody at 1:1000 at each lane.

Western blot analysis of lysates from KG-1, MCF-7, Western blot analysis of lysate from human placenta tissue MDA-MB-453 cell line (from left to right), using FOLR2 lysate, using FOLR2 Antibody at 1:1000. Antibody at 1:1000 at each lane.

September 28, 2021 1 https://www.prosci-inc.com/folr2-antibody-61-763.html FOLR2 Antibody IHC analysis in formalin fixed and Western blot analysis of lysate from mouse heart tissue lysate, paraffin embedded human spleen followed by using FOLR2 Antibody at 1:1000. peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse

This FOLR2 antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 18-46 amino acids from the N-terminal region of human FOLR2.

TESTED APPLICATIONS: Flow, IHC-P, WB

For WB starting dilution is: 1:1000 APPLICATIONS: For IHC-P starting dilution is: 1:10~50

PREDICTED MOLECULAR 29 kDa WEIGHT:

Properties

This antibody is purified through a A column, followed by peptide affinity PURIFICATION: purification.

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

September 28, 2021 2 https://www.prosci-inc.com/folr2-antibody-61-763.html Additional Info

OFFICIAL SYMBOL: FOLR2

Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental ALTERNATE NAMES: folate-binding protein, FBP, FOLR2

ACCESSION NO.: P14207

PROTEIN GI NO.: 116241366

GENE ID: 2350

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

FOLR2 is a member of the folate receptor (FOLR) family, and these exist in a cluster on 11. Members of this family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5- methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence BACKGROUND: homology with the FOLR1 and FOLR3 , respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.

1) Puig-Kroger, A., et al. Cancer Res. 69(24):9395-9403(2009) Boyles, A.L., et al. Genet. REFERENCES: Epidemiol. 33(3):247-255(2009) Franke, B., et al. Birth Defects Res. PartClin. Mol. Teratol. 85(3):216-226(2009)

ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.

September 28, 2021 3 https://www.prosci-inc.com/folr2-antibody-61-763.html