Anti-FOLR2 Purified Cat

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EXBIO Praha, a.s. • Nad Safinou II 341 • 252 50 Vestec • Czech Republic [email protected] • [email protected] • [email protected] • www.exbio.cz Technical Data Sheet Product Anti-FOLR2 Purified Cat. Number/Size 11-696-C025 0.025 mg 11-696-C100 0.1 mg For Research Use Only. Not for use in diagnostic or therapeutic procedures. Antigen FOLR2 Clone EM-35 Format Purified Reactivity Human Negative species Mouse Application FC (QC tested), IP, WB, ICC Application details Western blotting: Non-reducing conditions. Flow cytometry: Recommended dilution: 1-4 µg/ml Isotype Mouse IgG1 Specificity The mouse monoclonal antibody EM-35 recognizes an extracellular epitope on FOLR2, a 30-40 kDa cell surface protein serving as a receptor for folic acid. Other names Folate receptor beta, FBP, FR-P3, FR-BETA, BETA-HFR, FBP/PL-1 Immunogen BW5147alpha,beta- cells Entrez Gene ID 2350 Gene name FOLR2 NCBI Full Gene Name folate receptor beta UniProt ID P14207 Concentration 1 mg/ml Preparation Purified by protein-A affinity chromatography Formulation Phosphate buffered saline (PBS) solution with 15 mM sodium azide Storage and handling Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. Images and References www.exbio.cz The product is intended For Research Use Only. Diagnostic or therapeutic applications are strictly forbidden. Products shall not be used for resale or transfer to third parties either as a stand-alone product or as a manufacture component of another product without written consent of EXBIO Praha, a.s. EXBIO Praha, a.s. will not be held responsible for patent infringement or any other violations of intellectual property rights that may occur with the use of the products. Orders for all products are accepted subject to the Term and Conditions available at www.exbio.cz. EXBIO, EXBIO Logo, and all other trademarks are property of EXBIO Praha, a.s. Revision date: 2021-06-08.

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Anti-FOLR2 Antibody (ARG41860)
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46715389.Pdf
View metadata, citation and similar papers at core.ac.uk brought to you by CORE NIH Public Access provided by DigitalCommons@The Texas Medical Center Author Manuscript Birth Defects Res A Clin Mol Teratol. Author manuscript; available in PMC 2011 March 1. NIH-PA Author ManuscriptPublished NIH-PA Author Manuscript in final edited NIH-PA Author Manuscript form as: Birth Defects Res A Clin Mol Teratol. 2010 August ; 88(8): 689±694. doi:10.1002/bdra.20706. Association of Folate Receptor (FOLR1, FOLR2, FOLR3) and Reduced Folate Carrier (SLC19A1) Genes with Meningomyelocele Michelle R. O’Byrne1, Kit Sing Au1, Alanna C. Morrison2, Jone-Ing Lin2, Jack M. Fletcher3, Kathryn K. Ostermaier4, Gayle H. Tyerman5, Sabine Doebel6, and Hope Northrup1,7,* 1Department of Pediatrics, The University of Texas Medical School at Houston, Houston, Texas 2Human Genetics Center, The University of Texas School of Public Health at Houston, Texas 3Department of Psychology, University of Houston, Houston, Texas 4Texas Children’s Hospital, Houston, Texas 5Shriners Hospital for Children, Los Angeles, California 6The Hospital for Sick Children, University of Toronto, Ontario, Canada 7Shriners Hospital for Children, Houston, Texas Abstract BACKGROUND—Meningomyelocele (MM) results from lack of closure of the neural tube during embryologic development. Periconceptional folic acid supplementation is a modifier of MM risk in humans, leading to an interest in the folate transport genes as potential candidates for association to MM. METHODS—This study used the SNPlex Genotyping (ABI, Foster City, CA) platform to genotype 20 single polymorphic variants across the folate receptor genes (FOLR1, FOLR2, FOLR3) and the folate carrier gene (SLC19A1) to assess their association to MM.
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