Moderns ABC Plus of Biology Class 11 Part-I
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Special Edition Inside
A Publication by The American Society for the Pharmacology and Experimental Therapeutics Pharmacologist Inside: Feature articles from 2014-2015 Special Edition VISIT THE ASPET CAREER CENTER TODAY! WWW.ASPET.ORG/CAREERCENTER/ 4 5 12 21 30 41 WHAT YOU NEED: ASPET’S CAREER CENTER HAS IT 52 Jobseekers: Employers: No registration fee Searchable résumé database Advanced search options Hassle-free posting; online account management tools 61 Sign up for automatic email notifi cations of new jobs that Reach ASPET’s Twitter followers (over 1,000), match your criteria LinkedIn Members (over 2,000), and email subscribers (over 4,000) Free & confi dential résumé posting 71 Post to just ASPET or to entire NHCN network Access to jobs posted on the National Healthcare Career Network (NHCN) Sign up for automatic email notifications of new résumés that match your criteria Career management resources including career tips, coaching, résumé writing, online profi le development, Job activity tracking and much more ASPET is committed to your success: The ASPET Career Center is the best resource for matching job seekers and employers in the pharmacology and related health science fi elds. Our vast range of resources and tools will help you look for jobs, fi nd great employees, and proactively manage 9650 Rockville Pike, Bethesda, MD 20814-3995 your career goals. Main Office: 301.634.7060 www.aspet.org ASPET Career Center Full Page Ad 2015 Updated.indd 1 1/15/2016 3:18:16 PM The Pharmacologist is published and distributed by the American Society for Pharmacology and Experimental Therapeutics. THE PHARMACOLOGIST VISIT THE ASPET CAREER CENTER TODAY! PRODUCTION TEAM Rich Dodenhoff Catherine Fry, PhD WWW.ASPET.ORG/CAREERCENTER/ Judith A. -
Barbara Mcclintock's World
Barbara McClintock’s World Timeline adapted from Dolan DNA Learning Center exhibition 1902-1908 Barbara McClintock is born in Hartford, Connecticut, the third of four children of Sarah and Thomas Henry McClintock, a physician. She spends periods of her childhood in Massachusetts with her paternal aunt and uncle. Barbara at about age five. This prim and proper picture betrays the fact that she was, in fact, a self-reliant tomboy. Barbara’s individualism and self-sufficiency was apparent even in infancy. When Barbara was four months old, her parents changed her birth name, Eleanor, which they considered too delicate and feminine for such a rugged child. In grade school, Barbara persuaded her mother to have matching bloomers (shorts) made for her dresses – so she could more easily join her brother Tom in tree climbing, baseball, volleyball, My father tells me that at the and football. age of five I asked for a set of tools. He My mother used to did not get me the tools that you get for an adult; he put a pillow on the floor and give got me tools that would fit in my hands, and I didn’t me one toy and just leave me there. think they were adequate. Though I didn’t want to tell She said I didn’t cry, didn’t call for him that, they were not the tools I wanted. I wanted anything. real tools not tools for children. 1908-1918 McClintock’s family moves to Brooklyn in 1908, where she attends elementary and secondary school. In 1918, she graduates one semester early from Erasmus Hall High School in Brooklyn. -
Naturvidenskabernes Kanonisering. Forskere, Erkendelser Eller Kulturarv
NORDISK MUSEOLOGI 2006 G 2, S. 27-44 Naturvidenskabernes kanonisering. Forskere, erkendelser eller kulturarv KRISTIAN HVIDTFELT NIELSEN* Title: The ”canonisation” of the natural sciences. Abstract: This paper concerns recent official attempts to place science in Denmark within the context of a cultural canon. Based on differentiation between Mode 1 and 2 knowledge production, the paper points out that such attempts are highly contextualised and contingent on their different modes of application. Consequent- ly, they entangle scientific expertise with other social skills and qualifications. Like science museums and science centres, they are a means of dealing with science in the public agora, i.e. the public sphere in which negotiations, mediations, consulta- tions and contestations regarding science increasingly take place. Analysing the am- biguities and uncertainties associated with the recent official placing of science wit- hin an overall cultural canon for Denmark, this paper concludes that even though the agora embodies antagonistic forms of interaction, it might also lead the way to producing socially robust knowledge about science. Keywords: Cultural canon, science, Mode 1 and 2 knowledge production, Mode 2 society, agora, science museums, science centres. Naturvidenskab er ikke med i den officielle, denskabskanoner samt deres bredere betyd- danske kulturkanon, som blev sat i værk af ning for offentlighedens forståelse af naturvi- Kulturministeriet i 2005 (Kulturministeriet denskab, som jeg i denne artikel vil komme 2006). Det -
The Contributions of George Beadle and Edward Tatum
| PERSPECTIVES Biochemical Genetics and Molecular Biology: The Contributions of George Beadle and Edward Tatum Bernard S. Strauss1 Department of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, Illinois 60637 KEYWORDS George Beadle; Edward Tatum; Boris Ephrussi; gene action; history It will concern us particularly to take note of those cases in Genetics in the Early 1940s which men not only solved a problem but had to alter their mentality in the process, or at least discovered afterwards By the end of the 1930s, geneticists had developed a sophis- that the solution involved a change in their mental approach ticated, self-contained science. In particular, they were able (Butterfield 1962). to predict the patterns of inheritance of a variety of charac- teristics, most morphological in nature, in a variety of or- EVENTY-FIVE years ago, George Beadle and Edward ganisms although the favorites at the time were clearly Tatum published their method for producing nutritional S Drosophila andcorn(Zea mays). These characteristics were mutants in Neurospora crassa. Their study signaled the start of determined by mysterious entities known as “genes,” known a new era in experimental biology, but its significance is to be located at particular positions on the chromosomes. generally misunderstood today. The importance of the work Furthermore, a variety of peculiar patterns of inheritance is usually summarized as providing support for the “one gene– could be accounted for by alteration in chromosome struc- one enzyme” hypothesis, but its major value actually lay both ture and number with predictions as to inheritance pattern in providing a general methodology for the investigation of being quantitative and statistical. -
Nobel Prizes
W W de Herder Heroes in endocrinology: 1–11 3:R94 Review Nobel Prizes Open Access Heroes in endocrinology: Nobel Prizes Correspondence Wouter W de Herder should be addressed to W W de Herder Section of Endocrinology, Department of Internal Medicine, Erasmus MC, ’s Gravendijkwal 230, 3015 CE Rotterdam, Email The Netherlands [email protected] Abstract The Nobel Prize in Physiology or Medicine was first awarded in 1901. Since then, the Nobel Key Words Prizes in Physiology or Medicine, Chemistry and Physics have been awarded to at least 33 " diabetes distinguished researchers who were directly or indirectly involved in research into the field " pituitary of endocrinology. This paper reflects on the life histories, careers and achievements of 11 of " thyroid them: Frederick G Banting, Roger Guillemin, Philip S Hench, Bernardo A Houssay, Edward " adrenal C Kendall, E Theodor Kocher, John J R Macleod, Tadeus Reichstein, Andrew V Schally, Earl " neuroendocrinology W Sutherland, Jr and Rosalyn Yalow. All were eminent scientists, distinguished lecturers and winners of many prizes and awards. Endocrine Connections (2014) 3, R94–R104 Introduction Endocrine Connections Among all the prizes awarded for life achievements in In 1901, the first prize was awarded to the German medical research, the Nobel Prize in Physiology or physiologist Emil A von Behring (3, 4). This award heralded Medicine is considered the most prestigious. the first recognition of extraordinary advances in medicine The Swedish chemist and engineer, Alfred Bernhard that has become the legacy of Nobel’s prescient idea to Nobel (1833–1896), is well known as the inventor of recognise global excellence. -
Book of Abstracts
CHALLENGES FOR PLANT NUTRITION IN CHANGING ENVIRONMENTS International Workshop and Meeting of the German Society of Plant Nutrition 2012 University of Bonn September 5 – 8, 2012 Book of Abstracts Table of Contents Plenary Session: Introductory talks ................................................. 2 Plenary Session S1: Processes on leaf surfaces ................................. 5 Plenary Session S2: Plant water relations .......................................... 14 Plenary Session S3: Nutrient dynamics in changing environments .... 26 Plenary Session S4: Crop responses to nutrient imbalances ............. 38 Plenary Session S5: Phenotyping and early stress responses ........... 80 Poster Session P1: Fertilization (inorganic) ...................................... 92 Poster Session P2: Fertilization (organic) / Soil amendments ........ 110 Poster Session P3: Nutrient efficiency / Genomics ......................... 131 Poster Session P4: Root physiology / Root-soil interactions........... 148 Poster Session P5: Physiological response to abiotic stress .......... 169 Poster Session P6: Physiological response to nutrient imbalances 182 Poster Session P7: Nutrients and ecosystems / Climate change ... 200 Poster Session P8: Signalling / Quality / Phenotyping .................... 215 1 DGP Meeting September 5-9, 2012 Plenary Session: Introductory talks 2 DGP Meeting September 5-9, 2012 Plant nutrition in a changing environment. Patrick H. Brown Department of Plant Sciences, University of California, Davis, CA 95616, US; E-mail: [email protected] The scientific discipline of plant nutrition is wonderfully broad in its scale and its scope. From the exploration of the function of nutrients as signals and regulators of plant function, to the role of plant nutrients in agricultural productivity and food quality, to the exploration of the effects of nutrient losses on global environments, plant nutrition is a truly integrative discipline and will play a critical role in mans’ ability to adapt to environmental change. -
John Burchenal Oral History Interview
Joseph Burchenal Interview, January 26, 2001 1 National Cancer Institute Oral History Interview Project Interview with Joseph Burchenal Conducted on January 26, 2001 by Peggy Dillon Darien, Connecticut PD: Good morning. This is Peggy Dillon of History Associates Incorporated. I am speaking with Dr. Joseph Burchenal for the NCI oral history interview series. We are at his home in Darien, Connecticut. Today is January 26, 2001. JB: Good morning. PD: I would like to talk with you today about your work in cancer chemotherapy in general and also your involvement with the National Cancer Institute in particular. Before we get into your career overall and NCI, I'd like to ask you about your background. If you could just tell me a little bit about your upbringing and education . I understand that you were interested in chemistry from a very early age. JB: I was born in Milford, Delaware, but I lived in Wilmington, Delaware, for the first part of my life. My mother died when I was three, in childbirth. So I lived with my father in Wilmington. He was a lawyer. I went to school at Tower Hill School. The majority of my friends in the school had fathers or mothers–fathers mainly–who worked for Dupont. They were very likely to, so that there was a lot of interest in chemistry there. In fact, it was the same way on the street where we lived, where the fathers were mostly chemists. But my interest in chemistry, I guess, started when I was eight years old and I had a cousin who was eleven who was given a Chemcraft set and he used to show us all of the interesting things that he could do with it. -
Tierversuche in Der Forschung Senatskommission Für Tierexperimentelle Forschung Der Deutschen Forschungsgemeinschaft Tierversuche in Der Forschung 3 2
Senatskommission für tierexperimentelle Forschung der Deutschen Forschungsgemeinschaft Tierversuche in der Forschung Senatskommission für tierexperimentelle Forschung der Deutschen Forschungsgemeinschaft Tierversuche in der Forschung 2 3 Inhalt Vorwort �� � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � 4 Tierversuche und Tierschutz: Ethische Abwägungen Einführung �� � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � 6 Die Entwicklung des Tierschutzgedankens in Deutschland �� � � � � � � � � � � � � 39 Ethische Aspekte von Tierversuchen und das Solidaritätsprinzip� � � � � � � � 40 Tierversuche: Definition und Zahlen Die Übertragbarkeit aus ethisch-rechtlicher Sicht� � � � � � � � � � � � � � � � � � � � � � 45 Was ist ein Tierversuch? �� � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � 9 Das 3 R-Prinzip �� � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � 48 Wie viele Tiere werden verwendet? �� � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � 9 Alternativen zum Tierversuch� � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � 51 Wofür werden Tiere in der Forschung benötigt? �� � � � � � � � � � � � � � � � � � � � � � 11 Grenzen von Alternativmethoden� � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � 54 Welche Tierarten werden eingesetzt? �� -
Tierversuche in Der Forschung Senatskommission Für Tierexperimentelle Forschung Der Deutschen Forschungsgemeinschaft Tierversuche in Der Forschung 2 3
Senatskommission für tierexperimentelle Forschung der Deutschen Forschungsgemeinschaft Tierversuche in der Forschung Senatskommission für tierexperimentelle Forschung der Deutschen Forschungsgemeinschaft Tierversuche in der Forschung 2 3 Inhalt Vorwort . 4 Tierversuche und Tierschutz: Ethische Abwägungen Einführung . 6 Die Entwicklung des Tierschutzgedankens in Deutschland . 39 Ethische Aspekte von Tierversuchen und das Solidaritätsprinzip. 40 Tierversuche: Definition und Zahlen Die Übertragbarkeit aus ethisch-rechtlicher Sicht. 45 Was ist ein Tierversuch? . 9 Das 3 R-Prinzip . 48 Wie viele Tiere werden verwendet? . 9 Alternativen zum Tierversuch. 51 Wofür werden Tiere in der Forschung benötigt? . 11 Grenzen von Alternativmethoden. 54 Welche Tierarten werden eingesetzt? . 11 Die Basler Deklaration . 56 Europaweite Entwicklung . 14 Tierversuche in Deutschland: Vom Antrag bis zur Durchführung Tierexperimentelle Praxis: Einsatzbereiche für Versuchstiere Europäische Regelungen für Tierversuche . 59 Grundlagenforschung. 17 Tierversuche unter Genehmigungsvorbehalt . 60 Medizinische Forschung. 18 Rechtliche Grundlagen . 60 Nobelpreiswürdig: Herausragende wissenschaftliche Erkenntnisse . 20 Genehmigungsverfahren . 63 Diagnostik . 22 Durchführung von Tierversuchen . 64 Transplantationsmedizin . 25 Qualifizierte Überwachung. 68 Zell- und Gewebeersatz beim Menschen. 26 Belastungen für die Tiere . 69 Stammzellforschung . 27 Die Tierschutz-Verbandsklage . 71 Genomforschung . 28 Neurowissenschaften . 31 Anhang Veterinärmedizinische Forschung . 33 Tierversuche -
Physiologist President Earl H
THE AMERICAN PHYSIOLOGICAL SOCIETY Founded in 1887 for the purpose of promoting the increase of The physiological knowledge and its utilization. OFFICERS Physiologist President Earl H. Wood, Mayo Med. Sch., Rochester, MN President-Elect Francis J . Haddy, Uniformed Services Univ. of Hlth. Sci., Volume 24, No. 2, April 1981 Bethesda, MD Past President TABLE OF CONTENTS Ernst Knobil, Univ. of Pittsburgh HISTORICAL ARTICLES Council George H. Whipple --- Horace W. Davenport. Earl H. Wood, Francis J. Haddy, Ernst Knobil, Jack L. Kostyo, Centennial Celebration 5 S. McD. McCann, Paul C. Johnson, Leon Farhi SOCIETY AFFAIRS Executive Secretary-Treasurer Notes from Capitol Hill. 6 Orr E. Reynolds, 9650 Rockville Pike, Bethesda, Maryland Legislation and Animal Experimentation ... Earl Wood and Helene Cecil. 7 20014 Invitation to Membership in the NSMR. 9 SUSTAINING MEMBERS Frontiers in the Teaching of Physiology . 10 Abbott Laboratories Merrell Res. Ctr., Div. of APS Sections: How to Become Affiliated . ... 11 Burroughs Wellcome Co. Richardson-Merrell Inc. Member Contributions. 11 CIBA Geigy Corp. Pfizer, Inc. International Satellite Symposium. 12 Grass Instrument Co. Revlon Health Care Group Clearance Sale 18 Hoechst-Roussel Pharmaceu- A.H. Robins Co., Inc. Travel Awards and Application ... 19 tical Co., Inc. Sandoz, Inc. Membership Instructions and Application 21 Hoffmann-La Roche, Inc. G. D. Searle & Co. CAS Brief . 25 ICI Americas lnc. Smith Kline & French Labs. ANNOUNCEMENTS International Minerals & I.A. Squibb & Sons, Inc. Future Meetings. II Chemical Corp. The Upjohn Co. Symposium: Basic Biology of Muscles .. 5 Eli Lilly and Co. Waverly Press MIT Summer Course . 5 McNeil Laboratories Wyeth Laboratories, Inc. Fulbright Appointments 1981-83 10 Merck Sharp & Dohme Symposium on Respiratory System. -
Testing the Mьnch Hypothesis of Long Distance Phloem Transport in Plants
Downloaded from orbit.dtu.dk on: Oct 10, 2021 Testing the Münch hypothesis of long distance phloem transport in plants Knoblauch, Michael; Knoblauch, Jan; Mullendore, Daniel L.; Savage, Jessica A.; Babst, Benjamin A.; Beecher, Sierra D.; Dodgen, Adam C.; Jensen, Kaare Hartvig; Holbrook, N. Michele Published in: eLife Link to article, DOI: 10.7554/eLife.15341 Publication date: 2016 Document Version Publisher's PDF, also known as Version of record Link back to DTU Orbit Citation (APA): Knoblauch, M., Knoblauch, J., Mullendore, D. L., Savage, J. A., Babst, B. A., Beecher, S. D., Dodgen, A. C., Jensen, K. H., & Holbrook, N. M. (2016). Testing the Münch hypothesis of long distance phloem transport in plants. eLife, 5. https://doi.org/10.7554/eLife.15341 General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights. Users may download and print one copy of any publication from the public portal for the purpose of private study or research. You may not further distribute the material or use it for any profit-making activity or commercial gain You may freely distribute the URL identifying the publication in the public portal If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. RESEARCH ARTICLE Testing -
Balcomk41251.Pdf (558.9Kb)
Copyright by Karen Suzanne Balcom 2005 The Dissertation Committee for Karen Suzanne Balcom Certifies that this is the approved version of the following dissertation: Discovery and Information Use Patterns of Nobel Laureates in Physiology or Medicine Committee: E. Glynn Harmon, Supervisor Julie Hallmark Billie Grace Herring James D. Legler Brooke E. Sheldon Discovery and Information Use Patterns of Nobel Laureates in Physiology or Medicine by Karen Suzanne Balcom, B.A., M.L.S. Dissertation Presented to the Faculty of the Graduate School of The University of Texas at Austin in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy The University of Texas at Austin August, 2005 Dedication I dedicate this dissertation to my first teachers: my father, George Sheldon Balcom, who passed away before this task was begun, and to my mother, Marian Dyer Balcom, who passed away before it was completed. I also dedicate it to my dissertation committee members: Drs. Billie Grace Herring, Brooke Sheldon, Julie Hallmark and to my supervisor, Dr. Glynn Harmon. They were all teachers, mentors, and friends who lifted me up when I was down. Acknowledgements I would first like to thank my committee: Julie Hallmark, Billie Grace Herring, Jim Legler, M.D., Brooke E. Sheldon, and Glynn Harmon for their encouragement, patience and support during the nine years that this investigation was a work in progress. I could not have had a better committee. They are my enduring friends and I hope I prove worthy of the faith they have always showed in me. I am grateful to Dr.