Yearbook 17/18 ESCMID Yearbook 2017/2018 Table of Contents

Society Professional Affairs 2 Message from the President 55 Professional Affairs Overview 4 Message from the incoming President 56 ESCMID Collaborative Centres and 6 Changes to the ESCMID Executive Committee Observerships 8 Organizational chart 59 ECDC/ESCMID Observership 2017 60 WHO/ESCMID Observership 2017 Science 61 Mentoring 10 Scientiﬁ c Affairs 62 ESCMID Parity Commission 12 ESCMID Fighting Antimicrobial 63 Trainee Association of ESCMID (TAE) Resistance (AMR) 14 Study Groups International Networking 22 European Committee on Antimicrobial 65 ESCMID International Affairs Susceptibility Testing (EUCAST) in 2017– 2018 Subcommittee (EIAS) 26 European Committee on Infection Control (EUCIC) Awards & Grants 28 Emerging infections task force (EITaF) 2017 66 Awards and Grants 68 ESCMID Award for Excellence in Clinical Publications Microbiology and Infectious Diseases 29 Publications 69 ESCMID Young Investigator Awards 30 Clinical Microbiology and Infection for Research in Clinical Microbiology and 33 Medical Guidelines Infectious Diseases 34 ESCMID publications 70 ESCMID Research Grants 72 ESCMID TAE Awards for Training Education Achievements 40 ESCMID Educational Activities 72 ISF-ESCMID Sepsis Award 42 ESCMID Courses and Workshops 45 16th ESCMID Summer School Finances Borstel, Germany, 1 – 8 July 2017 74 Finances

Conferences Forthcoming Events 46 4th ESCMID Conference on Vaccines 76 Future Congresses Dubrovnik, Croatia, 8 – 10 September 2017 77 Forthcoming Events

ECCMID Acknowledgement of Reviewers 48 27th ECCMID from 22 – 25 April 2017 78 ECCMID abstract reviewers in Vienna, Austria 80 ESCMID research grant reviewers 51 28th ECCMID from 21 – 24 April 2018 in Madrid, Spain 82 Credits 52 Impressions ECCMID 2017

Viral electron microscopic images © Mateja Poljšak-Prijatelj, Marko Kolenc, Ljubljana Macroscopic / microscopic images © Ángel Ros Die, Valencia (page 82 Credits) nose, treat and prevent infection-related diseases than at ECCMID? Message from the President Thank you for making ECCMID 2018 one of the top scientiﬁc events of the year!

Ready for future challenges After six years of serving on the ESCMID Executive Committee, the last two as ESCMID President, it is time to hand over the reins to my successor, esteemed colleague and friend President-elect Jesús “A unique European approach to bring together Rodríguez Baño, who has accepted the challenging task of lead- clinical microbiologists and infectious ing the society for the next two years. Under my presidency, the ESCMID Executive Committee has continued to abide by the prin- disease specialists in one society and a joint ciple of primus inter pares – we decide and act as one family, as annual congress are the foundation of we have done over the years. These two years have been very demanding and busy, and I do not believe my family and colleagues ESCMID’s and ECCMID’s success and continued at my home laboratory would have looked kindly on a longer term. prosperity.” However, I am privileged to have been part of an exceptional team, greatly supported by the ESCMID Office, which has helped advance ESCMID on its path to becoming the most influential society in clin- Mario Poljak ical microbiology and infectious diseases. ESCMID President Past President Murat Akova is completing his term on the [email protected] ESCMID Executive Committee at ECCMID 2018. ESCMID’s current success would not have been possible without his vision, diploma- cy, commitment and inexhaustible energy – thank you Murat for your dedication and hard work over the past decade! Finally, I wish to congratulate Emmanuelle Cambau, clinical On the right track efit from the experience and expertise of mentors at ESCMID’s men- microbiologist from the University of Paris Diderot School of Medi- ESCMID is on the right track. ESCMID has the largest number of torship centres. Altogether, ESCMID funds its members’ research cine, Paris, France, and Önder Ergönül, infectious disease special- members ever, and we are heading towards another very success- projects, education, and training with more than EUR 700,000 ist from Koç University School of Medicine, Istanbul, Turkey, who ful annual ECCMID congress – and looking forward to what will every year. About EUR 300,000 of this is reserved every year for will join the ESCMID Executive Committee in April 2018. I am look- probably be the largest attendance ever. I strongly believe that ESCMID’s grant programme to finance promising research projects ing forward to working with them towards our common goals. the success and continued prosperity of ESCMID and ECCMID are of young ESCMID members. The centenary of the 1918 influenza pandemic is a moment to the result of the society’s unique approach, which brings together pause and reflect carefully on our capacity to respond to another clinical microbiologists and infectious disease specialists from all Shaping the profession worldwide epidemic. Such a prospect is troubling, even alarming. settings under one roof for timely diagnosis, treatment, and pre- ESCMID’s two committees, EUCAST and EUCIC, are progressing This is why we are here, united in our unique society, to hope for the vention of infection-related diseases. Our renowned comprehen- well. Under the auspices of ESCMID itself and the European Com- best but also prepare for the worst. This yearbook offers an over- sive, and multidisciplinary strategy is mirrored in the society’s mittee on Antimicrobial Susceptibility Testing (EUCAST), several view of ESCMID’s activities between two ECCMIDs. Enjoy your read structure, its committees and study groups, its research, educa- countries outside Europe are also establishing national antimi- and thank you for your interest in and contribution to our society. tional and professional activities, and ECCMID. crobial susceptibility testing committees, and increasingly more laboratories are implementing European breakpoints and methods. Born in Europe, acting globally Among many other projects, our second committee, the European Although European in name and in its general spirit, ESCMID at Committee on Infection Control (EUCIC), has just launched a com- the same time also understands that it can only be successful in prehensive two-year training programme with the goal of certify- fighting infectious diseases, which spread across the globe with- ing individuals trained in current infection prevention and control out regard for political or geographical borders, if it continuously practices and providing them with meta-competences from a Eu- promotes international cooperation and expands its reach be- ropean perspective. yond its home continent. The results of these efforts are seen in ESCMID collaborates closely with the European Union of Medi- the truly international ECCMID Programme Committee and its fac- cal Specialists (UEMS) to promote common European curricula ulty, ECCMID’s delegates from over 100 countries, the location of and exams for clinical/medical microbiology and infectious dis- the society’s workshops and postgraduate courses, in more than eases across the continent, and to ensure that both specialties are 100 ESCMID collaborative centres of excellence throughout the well recognized and attractive for generations to come. world and the prominent role of ESCMID members at major inter- ESCMID’s trainee association (TAE) and parity commission national meetings, on guideline committees, as well as in national are testimony to our commitment to trainees and young special- and international scientific and professional bodies. ists and to our support for groups that risk being underrepresented in training, research, educational, and professional activities. Science is our priority ESCMID brings together the best scientists in infectious diseases Sharing knowledge without limits and borders Executive Committee and in clinical/medical microbiology in its 30 dedicated study We are fortunate to have one of the best jobs in the world: working (l. to r.) Murat Akova, groups. Participating in one or more of ESCMID’s study groups of- in microbiology laboratories or hospital wards as clinical/medical Evelina Tacconelli, fers the opportunity to find collaborative research partners, to set microbiologists or infectious disease specialists. Our demanding Jesús Rodríguez Baño, the agenda of research conferences under the auspices of ESCMID, occupation requires constant education and peer-to-peer knowl- Annelies Zinkernagel, Mario Poljak, and to receive one of our generous research grants. Our younger edge dissemination and discussion. Is there any better place to Maurizio Sanguinetti, members are eligible for research and travel grants, and they ben- learn and discuss new approaches and practices on how to diag- Alex W. Friedrich

2 YEARBOOK 2017/2018 SOCIETY YEARBOOK 2017/2018 SOCIETY 3 Message from the incoming President

“The reinforcement of educational and research Figure 1. disease and clinical microbiology in all European countries and Type of membership beyond, in collaboration with UEMS-ID and UEMS-CM. Beyond that activities, medical guidelines as well as the basic we will work to promote the homogeneity of portfolios of services, full 2440 homogenization of professional training and re- young scientist performance and the quality of the clinical microbiology and infec- cognition of our specialities are set to help improve tious diseases department everywhere according to each society’s needs. We must increase our political infl uence so that the health 3367 the career prospects of our young colleagues.” problems related to infectious diseases and microbiology move up the agendas of decision-makers. We want ESCMID to be a transpar- Jesús Rodríguez-Baño ent and open society; open to its members worldwide, especially ESCMID President-elect and Secretary General its young members, with interest in any area of clinical microbiolo- [email protected] gy and infectious diseases. Our study groups continue to welcome 2060 new members, promoting their active contributions and providing member type them with opportunities to make their activities more visible to the scientifi c community. We will do our best to continue building a society our members can feel proud to be a part of. At this year’s ECCMID I will be taking over the presidency from my built from proposals from our members active in our network. The admired colleague Mario Poljak. I am looking forward to fulfi lling activities include face-to-face courses and workshops which facili- Changes in the Executive Offi ce this challenging role and to serving our members’ needs. As he has tate networking, allowing our younger members to make contact Samina Ahmed started as Professional Affairs Manager at the said, leading ESCMID is teamwork: the joint effort of the ESCMID with experts in an informal setting. In addition we are starting to Figure 2. ESCMID Executive Offi ce in July 2017, taking over from Dianne White, 129 Executive Committee with the valued assistance of our staff in produce e-learning activities and there is our very ambitious infec- Members by continent 254 who left after 15 years at the society. Science Manager Henri 731 Basel, and the collaboration of committees, subcommittees, study tion control training programme led by EUCIC. ESCMID also funds a Europe Saenz and Finance and HR Manager Milena Griffi ths left the Americas groups and our valued members. Having my name added to the list large number of research projects in all areas of infectious diseas- Asia society in April 2018. Henri has been with the society for almost of my distinguished predecessors is an honour. es and clinical microbiology, and participates in several European Oceania 869 12 years, while Milena joined ESCMID three years ago. We thank research projects. We also organize topic-specifi c conferences, Africa them for their valuable work and dedication to the society. In July Support members and support high-quality, commercial-free unbiased scientifi c ac- 2017 Executive Director Judith Zimmermann and Offi ce Adminis- Under my leadership the society will continue to provide support tivities organized by other scientifi c societies or institutions. We tration Offi cer Marc Balmer left to pursue careers outside ESCMID. to its members in research, education and their endeavours to are proud to support more than 60 of our affi liated societies and We thank them for their contributions and wish them all the best advance their professional careers, and we will do so whilst rein- partner with other scientifi c sister societies. ESCMID collaborative in their future careers. We warmly welcome Agnès Combebias, forcing our commitment to providing and promoting equality of centres are present on all continents, and our successful observer- 5885 who joined the society as Accountant in October 2017 and Simone opportunities for all our members regardless of their gender, race, ship and mentoring programmes provide unique opportunities to Brüderli who started as Offi ce Manager in March 2018. nationality or any other irrelevant aspect through our Parity Com- exchange experiences and to network. mission. Thanks ESCMID’s Activities I want to take this opportunity to thank all current and former Tackle challenges We are proud to see that ECCMID has been breaking all records Executive Committee members for their support and trust. Fulfi lling our goals has become more challenging and complex over in recent years, and has become the annual highlight for experts ESCMID’s success today would not have been possible without the the years, with our tasks affected by globalization, global warming, in the fi eld from all over the world; the most important congress 700 vision, commitment and inexhaustible energy of all the superb migration and refugee crises, overpopulation, and economic crises. combining clinical microbiology and infectious diseases. This is leaders the society has seen over the years – with some of whom 600 The outbreaks caused by emergent and re-emergent pathogens, obviously a consequence of the outstanding job done by the Pro- I have had the privilege to work. I also want to thank all those col- the worrisome spread of antimicrobial resistance, the rising rates gramme Director, the Programme Committees and everyone in- 500 leagues who over many weekends and late evenings wrote up or of sexually-transmitted infections and the increasing number of volved in the organization of this huge event. Our journal Clinical reviewed abstracts, manuscripts, research proposals or fi nalized persons predisposed to infections are only some of the challenges Microbiology and Infection has continuously and signifi cantly in- 400 the ECCMID scientifi c programme. Above all I want to thank Mario we are facing today. In response, ESCMID will continue to exert its creased its infl uence and prestige thanks to the outstanding work Poljak for his hard work and dedication to the society. During my infl uence beyond Europe, and will reinforce cooperation with spe- of all authors, reviewers and members of the editorial board, and 300 term we will proudly build on the work he and others started and cialists in adjacent disciplines and areas of research. The compre- it is clearly a priority for us to continue supporting its growth and follow the path to fulfi l our vision. The other members of the Ex- hensive multidisciplinary, one-health approach must remain our relevance. We will reinforce the development of medical guidelines, 200 ecutive Committee and I are looking forward to working with you core strategy as it is essential to tackling the complexity of the a portfolio where ESCMID’s expertise has received new impetus in towards our common goals and we will do our very best to live up 100 problems we are facing today. ESCMID will continue to adapt rap- recent years; another one of our current priorities. All these activi- to the trust you have placed in us. idly to the changing needs of the infectious diseases and clinical ties are possible only with the work and assistance of the ESCMID 0 microbiology community. Leading such a complex organization is managers at our executive offi ce whose commitment has contrib- Italy Spain Turkey far from easy but it is also thrilling. We are so lucky to have such an uted greatly to the success of our enterprises. France Australia active and committed membership. Germany Switzerland Netherlands Homogenization United States United Kingdom United Education and training ESCMID will continue to work towards the homogenization of ESCMID’s much appreciated educational and training activities are board-certifi ed training in the medical specialties of infectious Figure 3. Top membership countries

4 YEARBOOK 2017/2018 SOCIETY YEARBOOK 2017/2018 SOCIETY 5 Changes to the ESCMID Executive Committee

At the end of 2017 elections were held among the membership to ﬁ ll three positions on the ESCMID Executive Message of appreciation Committee; one for clinical microbiology and two representing infectious diseases. The members duly elected were Emmanuelle Cambau, a professor of microbiology at the School of Medicine of the University of Paris Diderot and Senior Medical Ofﬁ cer Bacteriology and Hygiene at Lariboisière Hospital in Paris, France as well as Önder Ergönül, a professor of infectious diseases and clinical microbiology at the Koç University School of Medicine, Istanbul, Turkey.

Emmanuelle and Önder will join the ESCMID Executive Committee in April 2018. Scientifi c Affairs Offi cer, Annelies Zinkernagel, from University Hospital Zurich, Switzerland, was successfully re-elected for a second term representing infectious diseases. We congratulate the newly and re-elected offi cers and are looking for- Murat Akova Service to the society ward to their contributions to the society. At this year’s ECCMID in April 2018, Publications and Communica- He was a driving force for the ESCMID Summer School in Cappa- tions Offi cer and Past-President Murat Akova will complete his term docia in 2010. He used his good connections in the region to or- on the ESCMID Executive Committee. We thank him for his much- ganize the educational event in this historical region in Central appreciated accomplishments and hard work as offi cer and presi- Anatolia, which was an unforgettable experience for everybody, New EC members dent, and we have no doubt that he will continue to stay closely participants and faculty alike. He repeated this once again in his connected to the society. home country in 2015, where he gave his full support to the school directors for another successful Summer School in Istanbul. More One of longest terms recently, as Publications Offi cer and Past-President, he shared his Murat has been a member of the ESCMID Executive Committee expertise and experience to modernize and rejuvenate the soci- since 2007. As one of the longest serving executives of the so- ety’s journal Clinical Microbiology and Infection, which today is a ciety in its more recent history, Murat contributed signifi cantly publication with an excellent reputation in the fi eld. He was also to the society’s successful development for more than a decade. instrumental in the reinforcement of the society’s medical guide- He helped shape ESCMID with his expertise and experience in the lines activities. He helped set up an effective professional process Emmanuelle Cambau (CM) Önder Ergönül (ID) management of infectious diseases. When he was responsible for allowing ESCMID to produce high-quality guidelines alone and in Emmanuelle has been an ESCMID member for two decades. She has Önder is an active infectious diseases physician, who also per- the education portfolio he was instrumental in the set-up, develop- cooperation with selected partners. As Communications Offi cer he been instrumental in the initiation of several activities, including forms clinical and epidemiological research. He was the president ment and streamlining of a process which allowed for a more effec- successfully raised the society’s profi le through both traditional the study group on mycobacterial infections and the EUCAST an- of KLIMIK, the Turkish society of clinical microbiology and infective evaluation of the society’s postgraduate educational courses and modern forms of communication. Thanks to his initiative, timycobacterial susceptibility testing committee, where she also tious diseases between 2013 and April 2017. He lives and works and the annual Summer School. As Scientifi c Affairs Offi cer he suc- ESCMID is seen today as a reference organization in the fi ght acted as chair. She was an active member of ESCMID’s Professional in Turkey, a country that connects different cultures and is con- cessfully aligned the research activities to focus on the outcomes against antimicrobial resistance by the public and policy makers Affairs Subcommittee, the study group on antibiotic resistance fronted with huge challenges in the fi eld of infectious diseases and of ESCMID’s projects and increase the number of publications in alike. We are sure that we will continue to see Murat at ESCMID’s surveillance and the ECCMID Programme Committee. Emmanuelle clinical microbiology. Önder embraces these challenges and sees renowned journals. educational events, which he will support with his experience, wants to further reinforce the link between clinical microbiology an opportunity to develop new approaches and solutions to tackle skills and kind personality. and infectious diseases by merging microbiological, epidemiologi- infection-related diseases. He is interested in organizing meetings ECCMID relocation cal and clinical aspects in the development of scientifi c, education- that will increase motivation for the profession. He helped organize As ESCMID President, he oversaw the organization of two highly Murat Akova al and professional activities. She is deeply involved with teams courses, all of which helped increase the professional and scien- successful ECCMIDs, 2015 in Copenhagen and 2016 in Amsterdam. Professor of Medicine Department of Infectious Diseases and Clinical Microbiology in several European countries, but is particularly interested in the tifi c capacity among the participants: on viral haemorrhagic fever The latter was successfully relocated to the Netherlands from its Hacettepe University School of Medicine promotion of ESCMID around the world. Emmanuelle would like to in 2008, Acinetobacter infections in 2010, and antimicrobial stew- originally planned location in Istanbul following political unrest in Ankara, Turkey improve the share of women and underrepresented countries in all ardship in 2017. Önder aims to promote the activities of ESCMID’s his home country, Turkey. During his presidency the society’s con- Member ESCMID Executive Committee 2007 – 2018 ESCMID-related educational, professional and scientifi c activities. Trainee Association and help extend ESCMID’s reach through its re- gress for the fi rst time clearly surpassed the 11,000-participant ESCMID President 2014 – 2016 Emmanuelle’s goals are to support and train younger colleagues search and educational activities in his region and throughout the mark. and those from countries with less access to knowledge and inno- world. vation to improve the outcome of patients suffering from infectious Founding member of ESGICH diseases and to raise the profi le of ESCMID and recognition of clini- Önder Ergönül Murat was one of the founding members of the society’s study cal microbiology worldwide. Professor of Infectious Diseases and Clinical Microbiology group on immunocompromised hosts, ESGICH, which today is one Head of Infectious Diseases and Clinical Microbiology Department of ESCMID’s most active research groups. He initiated the coopera- Emmanuelle Cambau Koç University School of Medicine tion between ESCMID and the European Organisation for Research Professor in Microbiology, School of Medicine, Istanbul, Turkey and Treatment of Cancer (EORTC) and the European Conference on University of Paris Diderot Senior Medical Offi cer, bacteriology-hygiene Infections in Leukaemia (ECIL), a partnership that resulted in the laboratory at Lariboisière Hospital, production of a series of game-changing guidelines on the man- Paris, France agement of infectious diseases in immunocompromised patients.

6 YEARBOOK 2017/2018 SOCIETY YEARBOOK 2017/2018 SOCIETY 7 Organizational chart

Executive Committee members

Current Members

Mario Poljak Jesús Rodríguez Alex W. Friedrich Annelies Evelina Tacconelli Maurizio Murat Akova Ljubljana, SI Baño Groningen, NL Zinkernagel Tübingen, DE Sanguinetti Ankara, TR Seville, ES Zurich, CH Rome, IT (Past President) Ad hoc EC members

Members as of 23 April 2018

Jesús Rodríguez Maurizio Alex W. Friedrich Annelies Önder Ergönül Emmanuelle Mario Poljak Evelina Tacconelli Winfried V. Kern Leonard Leibovici Luigia Scudeller Christian Giske Tbd Baño Sanguinetti Groningen, NL Zinkernagel Istanbul, TR Cambau Ljubljana, SI Tübingen, DE Freiburg, DE Tel Aviv, IL Pavia, IT Stockholm, SE Seville, ES Rome, IT Zurich, CH Paris, FR

General Affairs General Affairs Finance Science Education Professional Publications Medical Guidelines ECCMID CMI Medical EUCAST International President President-elect & Treasurer & Scientifi c Affairs Education & Affairs Publications Offi cer Medical Guidelines Programme Director Editor-in-Chief Guidelines Chairperson Affairs Secretary General Financial Support O f fi c e r Communications Professional & Immediate Past O f fi c e r Director Director O f fi c e r O f fi c e r Affairs Offi cer President

ESCMID Council Scientiﬁ c Affairs Education Professional Affairs Publication ECCMID Programme International Affairs Subcommittee Subcommittee Subcommittee Subcommittee Committee Subcommittee

Study Groups Parity Commission, TAE

Executive Ofﬁ ce

Simone Brüderli Agnès Combebias Milena Griffi ths Henri Saenz Thomas Greif Samina Ahmed Chantal Britt Nancy Gerits Carla Seiler Offi ce Manager Accounting Manager Finance & Scientifi c Manager Education Manager Professional Affairs Communications Publications & Event Coordination HR Manager Manager Manager Medical Guidelines Manager Manager

8 YEARBOOK 2017/2018 SOCIETY YEARBOOK 2017/2018 SOCIETY 9 Scientiﬁc Affairs www.escmid.org/science

“In addition to awards and funding which provide great motivation it is the ever expanding ESCMID network of very knowledgable scientists and specialists relying on the scientiﬁc affairs subcommittee and our study groups which is the key driver of the scientiﬁc and medical progress.”

Annelies Zinkernagel ESCMID Scientiﬁc Affairs Ofﬁcer [email protected]

Research grants Awards Annually around 15 excellent researchers receive a research grant The Young Investigator Award acknowledges outstanding individual for their submitted proposals; this programme continues to be high- researchers and both honours as well as spreads ground-break- ly popular with our members (see page 66 Awards & Grants) and ing work. This year we honour Evgeny Idelevich, a clinical micro- very productive in terms of publications (see page 29 Publications). biologist from the University Hospital Münster, Germany, for his work on rapid sepsis diagnostics and susceptibility testing; and Study groups James Price, a research lecturer at the Brighton and Sussex Medi- Last year I wrote that a medical society is a network of peers, who cal School, United Kingdom, for developing strategies to prevent collaborate to advance knowledge and help translate it into prac- healthcare-associated infections by multidrug-resistant organ- tice. Our study groups are the core of our society with many and isms (see page 69 Young Investigators). Quick action to prevent or Scientific Affairs Subcommittee Meeting in 2017 diverse activities (following pages) and are the key drivers of diagnose life-threatening infections is most relevant today. (l. to r.) Oliver Dyar, Luigi Gradoni, Frédéric Laurent, Adriana Vince, Andreas Groll, scientific and medical progress. During the past year, we saw the Mona Johannessen, Gilbert Greub, Annelies Zinkernagel (Scientific Affairs Officer), Souha Kanj, Henri Saenz (Science Manager) foundation of two new groups, one on public health microbiology Scientific Affairs Subcommittee and one on respiratory viruses (see page 14 New Study Groups ) – Finally I would like to thank the Scientific Affairs Subcommittee so now there are 30 study groups active within ESCMID. (SAS) for their never-ceasing dedication to advance our projects and embrace new ideas. Thank you! Following suggestions by SAS The ESCMID network members, we have, among other things, adapted the format of the All the above is led and facilitated by the network of ESCMID com- Scientific Affairs Meeting at ECCMID, the most important platform Scientific Affairs Subcommittee mittees and subcommittees. The groups within this network inter- within Scientific Affairs, bringing together the SAS and representa- act with and influence each other. tives of all study groups plus the ECCMID Programme Director and ESCMID sections and section leaders EUCAST (see page 22 EUCAST) per se was originally the net- Medical Guidelines Director to exchange new ideas. The new format • Bacteria & bacterial diseases (Oliver Dyar, Stockholm, Sweden) work of a study group which has spread its net very successfully allows more sharing of information and includes networking time • Fungi & fungal diseases (Andreas Groll, Münster, Germany) worldwide. The latest development is EUCAST’s proposal to modify to follow up individually on potential collaborative project ideas. We • Parasites & parasitic diseases (Luigi Gradoni, Rome, Italy) the definitions of susceptibility categories S, I and R and to intro- all look forward to another productive year. • Viruses & viral diseases (Adriana Vince, Zagreb, Croatia) duce an area of technical uncertainty (ATU). ESCMID themes and theme leaders EUCIC (see page 26 EUCIC) – founded in 2014 – now offers a • Pathogenesis & immunology (Mona Johannessen, Tromsö, Norway) training programme allowing the sharing of expertise and compe- • Epidemiology, public health & vaccinology tencies amongst training centres, countries and professions close- (Carolina Garcia Vidal, Barcelona, Spain) ly reflecting ESCMIDs spirit. This collaborative effort will result in • Clinics & therapeutics (Souha Kanj, Beirut, Lebanon) • Diagnostics (Gilbert Greub, Lausanne, Switzerland) the training of a new generation of infection prevention and control • Antimicrobial resistance & susceptibility testing specialists. (Frédéric Laurent, Lyon, France) The objectives of the recently established ESCMID emerging infections task force (see page 28 EITaF) are to provide up-to-date For more information see www.escmid.org/science. information on outbreaks with epidemic or pandemic potential, to evaluate threat levels and to stimulate research on emerging infections, including surveillance and diagnostics.

10 YEARBOOK 2017/2018 SCIENCE YEARBOOK 2017/2018 SCIENCE 11 Poor infection control European Committee on Antimicrobial ESCMID fi ghting antimicrobial resistance (AMR) Susceptibility Testing EUCAST www.escmid.org/fi ghtingresistance European Committee on Infection • Defi nition and review of Control EUCIC optimal dosing of antibiotics • Implements infection control and to treat existing and newly preventive measures to reduce the emerging bacterial species burden of healthcare-associated • Optimization of antibiotic infections susceptibility testing methods • Launched the EUCIC Infection • Surveys on antibiotic susceptibility ESCMID’s role in the fi ght against AMR Excessive agricultural Prevention and Control Certifi cate, use & One Health the fi rst European training Study Group for Antimicrobial • Conducts research and organizes courses and conferences programme of its kind, which will Resistance Surveillance ESGARS, on surveillance, infection control, stewardship EUCAST Veterinary Subcommittee integrate courses at an international Study Group for Bloodstream level with national courses in Infections and Sepsis ESGBIS, • Holds annual congress ECCMID, the largest platform for AMR on Antimicrobial Susceptibility selected EUCIC excellence centres, Study Group for Infections in Com- research presentations and discussions Testing VetCAST • Received funding within the joint creating a network of faculty and promised Hosts ESGICH • Provides expert advice on One Health antimicrobial resistance programming initiative on anti- trainees in different European • Contribute to INCREMENT-SOT policies at a national, European and international level microbial resistance regions to enable trainees to acquire project, which studies bloodstream (WHO priority list on resistant pathogens) • Position paper on proposed VetCAST European competence in the fi eld of infections caused by multidrug- infection prevention and control resistant Enterobacteriaceae in solid • Partner in WHO’s antimicrobial resistance surveillance project approach on breakpoints • Updating the recommendations on organ transplantation CAESAR Study Group for Veterinary the practices and rituals in the • Supports and organizes public and specialist awareness Microbiology ESGVM operating theatre, jointly with the Study Group for Implant-Associated campaigns • Educational antibiotic stewardship Healthcare Infection Society, UK Infections ESGIAI, Study Group for Antimicrobial Stewardship ESGAP, • Helps assess and speed up the development of new diagnostic project PREPARE-VET on anti- Study Group for Infections in methods and drug therapies biotic use and resistance at over 100 veterinary schools in Prescription and therapy the Elderly ESGIE, Study Group for 31 European countries Nosocomial Infections ESGNI, Study • Funding of research project to Study Group for Antimicrobial Group for Critically Ill Patients ESGCIP, evaluate tools to identify veterinary Stewardship ESGAP Study Group for Bloodstream Infec- pathogens • Surveys of antibiotic prescribing tions and Sepsis ESGBIS, Study Group • Co-organized workshop on Lack of new • Training in antimicrobial steward- for Clostridium diffi cile ESGCD antimicrobial susceptibility testing ship, diagnosis and management of • Contribute to project on anti- in Toulouse antimicrobials drug-resistant infections, antimicrobial prescribing and steward- • Course on antimicrobial steward- microbial susceptibility testing and ship (ESCAPS) to explore a consen- ship in veterinary medicine PK/PD of Anti-Infectives Study Group surveillance sus for antimicrobial prescribing EPASG • Nine articles in several scientifi c and stewardship competencies Fungal Infection Study Group EFISG • Article on role of infection models journals and antimicrobial steward- • Antifungal stewardship and PK/PD modelling for optimizing ship book Study Group for Staphylococci and • Research and information on care of critically ill patients with • Over ten research projects, including Staphylococcal Diseases ESGS emerging fungal resistance severe infections several surveys on antimicrobial • Articles about MRSA infections • Study of interactions • Annual study grant of EUR 1,000 stewardship among patients between agricultural use of to foster collaboration across • Co-organized course on diagnosis antifungals and human medicine laboratories and help mentor young Study Group for Nosocomial of bloodstream infections investigators Infections ESGNI • Contributes to study on multi- • Anti-infective PK/PD conference on • Co-organized an ESCMID course resistant neonatal sepsis- 21 April 2017 in Vienna – Hospital-acquired infections: associated Staphylococcus capitis • Pipeline Corner at ECCMID understanding the magnitude and needed interventions, 24 – 25 March 2017 in Muscat, Oman Lack of rapid diagnostics

Study Group for Genomic and Molecular Diagnostics ESGMD • Project for AMR rapid diagnostic Non-compliance & test, consortium AMR-RDT within lack of hygiene joint programming initiative on AMR JPIAMR Study Group for Antibiotic Policies • Study of whole-genome and ESGAP phenomic investigation of the traits • Public campaigns on AMR and that favoured the predominance antimicrobial stewardship and shift to OXA-23-producing IC2 isolates in carbapenem-resistant Acinetobacter baumannii

12 YEARBOOK 2017/2018 SCIENCE YEARBOOK 2017/2018 SCIENCE 13 Study Groups Existing Study Groups www.escmid.org/studygroups

Here we look back over the many activities performed by our study groups in the calendar year 2017. The following pages show a selection of major achievements or ongoing activities of the individual study groups. In general the study groups strongly contribute to ECCMID’s scientiﬁ c programme by proposing symposia, educational workshops and meet-the-expert sessions. They organize the majority of courses/workshops for the ESCMID education programme (see page 40 Education) and publish a number of scientiﬁ c articles in ESCMID’s name (see page 29 Publications).

• Published an editorial – Diagnosing fungal infections in haema- • Co-sponsored summer course – Genomics in foodborne patho- tology patients – another case of less is more in the clinical set- gen surveillance and outbreak investigation, 12 – 13 July 2017 New Study Groups ting? (Clin Microbiol Infect 2017;23:896-7). in Vitoria-Gasteiz, Spain. • Organized the IV Meeting of the ECMM/ISHAM working group fun- • Completed the study group research project – Discrimination gal respiratory infections in cystic ﬁ brosis (Fri-CF), 5 – 6 June of Salmonella non-typhoid high-risk clones by high-throughput 2017 in Osuna, Spain, and co-organized three ESCMID work- spectroscopic techniques (MALDI-TOF and FTIR-ATR). shops and courses jointly with several other study groups. • Runs European, multi-centre, prospective prevalence pilot-study • Currently there are four active research projects including – of Cronobacter sakazakii infections in humans (EUCRONI). Medical Guideline project EFISG, MixInYest: a multicentre survey on mixed yeast infections in Europe, European survey on antifungal therapy duration for invasive aspergillosis and Scedo- Lung: practice survey on Scedosporium colonization and infection in lung transplant recipients.

The newly founded ESCMID study group for public health micro- The ESCMID study group for respiratory viruses (ESGREV) was biology (ESGPHM) started its activities earlier this year. Main established very recently. Main objectives are to: objectives are to: • bring together Europe’s leading experts on respiratory viruses • create an interdisciplinary platform for collaboration of clinical • help reduce the burden of respiratory viruses in society by microbiologists, infectious disease epidemiologists and infec- – advancing scientifi c knowledge tious disease clinicians on public health issues; – raising public awareness through educational activities • provide information and training about the principles of micro- – stimulating collaborative projects and communication biology, epidemiology and public health practice towards the between scientists who are interested in this fi eld detection, surveillance, investigation, and control of microbial diseases; • increase awareness of the crucial role of public health microbiol- • Published an article – The role of infection models and PK/PD • Co-organized the ESCMID capacity-building workshop – Appli- ogy in infectious disease control in outbreak detecting, emerg- modelling for optimising care of critically ill patients with severe cation of MALDI-TOF MS in clinical microbiology – together with ing infections, and treatment failures, in addition to strengthen- infections – in collaboration with ESGICH and ESGCIP (Intensive ESGMD and ESGEM, 13 – 15 March 2017 in Basel, Switzerland. ing laboratory capacity on a global level; Care Med 2017;43(7):1021-32). • Runs joint initiative of seven laboratories with specifi c expertise • create a platform for public health microbiology trainees to pre- • Distributes an EPASG study grant of EUR 1,000 annually to fos- – ENRIA (European network for the rapid identifi cation of anaer- sent their research results to clinical microbiologists/infectious ter collaboration across laboratories and help mentor young in- obes), which is supported by ESGAI and ESGEM. disease specialists and other affi liated disciplines; vestigators. • Runs the research project – Isolation and analysis of antibi- • improve the transfer of knowledge between different countries • Organized the conference Anti-infective PK/PD – integrating otic resistance and presence of the resistance genes in Bac- in Europe regarding new methods and insights in public health knowledge and innovating therapies, held on 21 April 2017 in teroides/Parabacteroides strains from faecal samples collected microbiology. Vienna, Austria. from eight European countries.

14 YEARBOOK 2017/2018 SCIENCE YEARBOOK 2017/2018 SCIENCE 15 • Published nine original articles in several scientifi c journals and • Co-organized two ESCMID courses and EORTC/ESCMID brain- • Published four articles in 2017, including – To test or not to test? • Published a review – How to: establish and run a stool bank. a book, Antimicrobial Stewardship (published in April 2017 by El- storming meeting jointly with several other study groups. Laboratory support for the diagnosis of Lyme borreliosis: a (Clin Microbiol Infect 2017;23(12):924-30) and contributed to sevier). • Participates in the surveillance system for Eastern Europe and position paper of ESGBOR, the ESCMID study group for Lyme six other publications in various scientifi c journals. • Co-organized several educational and ESCMID courses on vari- Central Asia (CAESAR) in collaboration with WHO Europe and borreliosis. (Clin Microbiol Infect 2018;24(2):118-24). • Co-organized workshop on microbiological support to European ous aspects of antimicrobial stewardship. RIVM with microbiological capacity-building as well as methodol- • Co-organized the international symposium on ticks, tick-borne surveillance of Clostridium diffi cile with ECDC, 11 – 12 May 2017 • Runs over ten research projects, including several surveys in ogy for surveillance and interpretation of the data. pathogens and disease (ITPD 2017), 24 – 26 September 2017 in in Vienna, Austria. the area of antimicrobials and antimicrobial stewardship. • Runs joint project INCREMENT-SOT (an international consortium Vienna, Austria. • Currently runs several research projects, including standardi- for the clinical study of bloodstream infections caused by mul- • Runs fi ve collaborative projects, including IDSA’s Lyme borreliosis zation of faecal microbiota transplantation in collaboration with tidrug-resistant Enterobacteriaceae in solid organ transplanta- medical guideline project. United European Gastroenterology (UEG) and European surveil- tion) together with ESGBIS, ESGICH and the Spanish Network for lance of CDI in collaboration with ECDC. Research in Infectious Diseases (REIPI).

• Organized its bi-annual scientifi c conference EuroBiofi lm 2017, • Published and contributed to seven publications in various sci- • Published and contributed to several articles in various scien- • Published two ESGCP articles based on its research projects, 19 – 22 September 2017 in Amsterdam, Netherlands. entifi c journals. tifi c journals, including – Use of nebulized antimicrobials for the including – Genetic diversity of Plasmodium vivax metacas- • Runs an annual online course on biofi lms. • Co-organized two courses in 2017 jointly with several other treatment of respiratory infections in invasively mechanically pase 1 and Plasmodium vivax multidrug-resistance 1 genes • Co-organized an ESCMID postgraduate education course – Im- study groups. ventilated adults: a position paper from ESCMID. (Clin Microbiol of fi eld isolates from Mauritania, Sudan and Oman. (Malar J proving the diagnosis of bloodstream infections – advancing • Currently there are nine active international collaborative Infect 2017;23(9):629-39). 2017;16(1):61). technology and quality for better care, 28 – 31 March 2017 in projects coordinated or co-organized by ESGBIS where many • Co-organized three ESCMID courses jointly with several other • Recently completed the study group research project – Review- Nice, France. European countries are represented, including two large clinical study groups. ing prevention measures and evaluating the burden of toxoplas- studies on bloodstream infections: INCREMENT and BICHROME. • Completed several study group research projects in 2017, in- mosis in transplant patients in European countries. cluding Prospective evaluation of incidence, risk factors and • Runs a research project – Molecular epidemiology of Plasmo- outcomes for patients with ventilator-associated events in Euro- dium vivax in the Sultanate of Oman. pean intensive care units.

16 YEARBOOK 2017/2018 SCIENCE YEARBOOK 2017/2018 SCIENCE 17 • Co-organized three ESCMID capacity-building workshops jointly • Published an article – How is post-mortem microbiology ap- • Published two research articles, including – Multinational case- • Contributed to four publications, including an article – Predictors with several other study groups in Switzerland, Germany, and praised by pathologists? Results from a practice survey control study of risk factors for the development of late invasive of mortality in nursing-home residents with pneumonia: a multi- Israel, respectively. conducted by ESGFOR. (Eur J Clin Microbiol Infect Dis 2017; pulmonary aspergillosis following kidney transplantation. (Clin centre study. (Clin Microbiol Infect 2018;24(1):72-77). • Co-organized the ESCMID advanced technical workshop – Infec- 36(8):1381-5). Microbiol Infect 2018;24(2):192-198). • Runs a research project – ESCMID study groups’ competencies tion and resistance prevention in the regional healthcare net- • Co-organized the ESCMID postgraduate education course – Re- • Runs two projects, including an INCREMEN-SOT study, and is in antimicrobial prescribing and stewardship (ESCAPS) – jointly work, 1 – 2 June 2017 in Groningen, Netherlands. gional capacity-building for integration of next-generation se- currently preparing ESCMID guidelines for the diagnosis and with ESGAP, ESGNI, ESGIAI, ESGCIP, ESGBIS, and ESGCD in order to • Co-organized the ESCMID postgraduate education course – Im- quencing in the clinical microlab, 29 – 31 October 2017 in Her- management of Aspergillus diseases in collaboration with EFSIG, explore a consensus for antimicrobial prescribing and steward- proving the diagnosis of bloodstream infections – advancing zliya, Israel. ECMM and ERS. ship competencies. technology and quality for better care, 28 – 31 March 2017 in • Applied for two new collaborative projects, including – Pilot • Co-organized an ESCMID course on viral infections in immuno- • Completed the study – The participation of the elderly in rand- Nice, France. study: targeted 16S-23S rDNA next generation sequencing: compromised patients, 8 – 9 June 2017 in Bratislava, Slovakia, omized controlled trials of antibiotic treatment. useful in identifying an infectious cause of death? and an EORTC/ESCMID brainstorming meeting on 14 February 2017 in Brussels, Belgium.

• Organized an ESCMID course – Update on infections associated • Published an article – An update on bacterial brain abscess in • Runs a research project – Infectious diseases screening and • Published ﬁ ve research articles, including – Rapid detection and with orthopaedic implants: diagnosis and management – jointly immunocompetent patients (Clin Microbiol Infect 2017;23(9): vaccination policy for migrants in Europe. evolutionary analysis of Legionella pneumophila serogroup 1 with Clínica Universidad de Navarra, GEIH and SEIMC, 7 – 9 June 614-620) and contributed to nine other publications. • Secured 20 free registrations to ECCMID 2018 for refugee medi- sequence type 47. (Clin Microbiol Infect 2017;23(4):264.e1-264. 2017 in Pamplona, Spain. • Organized an ESCMID course – Omics of host and pathogens cal professionals. e9), and a revision of ESGLI/EWGLI technical guidelines for con- • Runs several multi-centre studies, including a retrospective co- during infections – jointly with ESGMD and Medical University of • Prepared an ESGITM-ESGICH consensus document – Recom- trol and prevention of travel associated Legionnaires’ disease. hort study on late acute prosthetic joint infections that includes Grenoble, 6 – 8 September 2017 in Grenoble, France. mendations on travel medicine and management of endemic • Co-organized an ESCMID course – Regional capacity-building for more than 30 centres from different countries. The study results • Runs a research project – Epigenetic control of meningeal path- diseases in solid organ transplant recipients, currently in the integration of next-generation sequencing in the clinical micro- are in the publication stage. ogenicity of Listeria monocytogenes. publication process. lab, 30 Oct – 1 Nov 2017, in Herzliya, Israel. • Runs a project – ESCMID study groups’ competencies in anti- • Runs a research project – Microbiome analysis of drinking water microbial prescribing and stewardship (ESCAPS) to explore a systems: evaluation of new approaches for prevention and con- consensus for antimicrobial prescribing and stewardship com- trol of Legionnaires’ disease. petencies – together with ESGAP, ESGNI, ESGIE, ESGCIP, ESGBIS and ESGCD.

18 YEARBOOK 2017/2018 SCIENCE YEARBOOK 2017/2018 SCIENCE 19 • Organized an EORTC/ESCMID brainstorming meeting on 14 Feb- • Published a research article – Multi-centre evaluation of one • Published two research articles, including – MRSA infections • Published two research articles, including – Availability of hepa- ruary 2017 in Brussels, Belgium, and co-organized fi ve ESCMID commercial and 12 in-house real-time PCR assays for detection among patients in the emergency department: a European mul- titis C diagnostics and therapeutics in European and Eurasian courses, including a capacity-building workshop – Applications of Mycoplasma pneumoniae. (Diagn Microbiol Infect Dis 2017; ticentre study. (J Antimicrob Chemother 2017;72(2):372-375). countries. (Antiviral Res 2017;150:9-14) of MALDI-TOF mass-spectrometry in clinical microbiology, 13 – 88(2):111-114). • Co-organized an ESCMID course – Improving the diagnosis of • Collaborates with the European society for translational antiviral 15 March 2017 in Basel, Switzerland. • Published an editorial – Mycoplasma pneumoniae clinical mani- bloodstream infections – advancing technology and quality for research (ESAR) on a European database on anti-HCV therapy • Completed the project – Pilot study on the microbiome of the ap- festations, microbiology and immunology. (Front Microbiol 2017; better care, 28 – 31 March 2017 in Nice, France. failure (hepatitis C antiviral therapy failure registry, HepCaRe) pendix and gut in acute appendicitis. 8:1916). • Runs two projects jointly with other study groups – ESCMID prac- which includes 15 European centres. • Currently runs two research studies – Improvement of spe- tice guideline on the management of S. aureus bloodstream in- • Enabled two 6-month international exchanges for infectious dis- cies-level detection and identifi cation of non-tuberculous my- fection, and Evolution history and large-scale phylogeography of eases trainees in the fi eld of HIV and hepatitis. cobacteria using matrix-assisted laser desorption/ionization the multiresistant, neonatal sepsis-associated Staphylococcus time-of-fl ight mass spectrometry (MALDI-TOF MS), and Carbap- capitis clone NRCS-A. enem-resistant Acinetobacter baumannii: whole-genome and phenomic investigation of the traits that favoured the predominance and shift to OXA-23-producing IC2 isolates.

• Runs a research study – Development of a reference method • Co-organized an ESCMID course – Hospital-acquired infections: • Published a review article – Diagnostic microbiology in vet- • Published two articles – Strategies to develop vaccines of pae- for MIC-testing of Mycobacterium tuberculosis as a basis for evi- understanding the magnitude and needed interventions, 24 – erinary dermatology: present and future. (Vet Dermatol 2017; diatric interest. Esposito S, Principi N, ESCMID Vaccine Study dence based clinical breakpoints. 25 March 2017 in Muscat, Oman. 28(1):146-e30). Group (EVASG). Expert Rev Vaccines. 2017;16(2):175-186. and • Collaborates with WHO on drug resistance in leprosy and with • Runs a research study on a consensus for antimicrobial pre- • Co-organized a VETCAST/EUCAST 2017 workshop – Antimicrobial The 26th European Congress of Clinical Microbiology and Infec- EMA and WHO on new antimycobacterial drugs. scribing and stewardship competencies together with several susceptibility testing with VETCAST breakpoints: quantitative tious Diseases (ECCMID) in Amsterdam, the Netherlands. Es- • Runs a medical guideline project – Non-tuberculous mycobac- different study groups. methods, 12 – 15 September 2017, in Toulouse, France. posito S, Poljak M; ESCMID Vaccine Study Group (EVASG). Hum teria, and a study – MDR-TB in migrants to Europe: a database • Is currently updating the recommendations on the practices and • Runs an educational project – PREPARE-VET (prescriber per- Vaccin Immunother. 2017;13(1):151-152. analysis and systematic review. rituals in the operating theatre, jointly with the development spectives on antibiotic use and resistance education in Europe committee of HIS, UK. – veterinary medicine) which aims to evaluate the quality of education on antimicrobial stewardship of ﬁ nal year veterinary students and includes 101 veterinary schools from 31 European countries.

20 YEARBOOK 2017/2018 SCIENCE YEARBOOK 2017/2018 SCIENCE 21 European Committee on Antimicrobial Susceptibility Testing (EUCAST) in 2017 – 2018 www.eucast.org

EUCAST provides breakpoints and antimicrobial susceptibility National AST committees (NACs) 90,000 Figure 1. testing methods. ESCMID is the administrative, financial and sci- Most European countries have established NACs. Further efforts Unique pageviews for entific framework for EUCAST. ESCMID (www.escmid.org), the on recruiting the remaining EU/EEC member countries are ongoing. 80,000 eucast.org 2014 – 2017 2017 ESCMID Förderverein (www.escmid-fv.org) and the European Cen- Interest in EUCAST in countries outside the European Union con- 70,000 2016 tre for Disease Prevention and Control (ECDC; www.ecdc.europa.eu) tinued to increase, leading to the establishment of NACs in coun- 2015 supported EUCAST financially in 2017. ESCMID supports the devel- tries such as China, FYR Macedonia, New Zealand and Serbia. NACs 60,000 2014 opment of the EUCAST disk diffusion method. provide national input to all aspects of EUCAST, promote national 50,000 strategies for susceptibility testing and help to implement EUCAST EUCAST Steering Committee breakpoints and methods. 40,000 The steering committee met five times during 2017 and dealt with 30,000 many aspects of breakpoints and antimicrobial susceptibility test- EUCAST Network Laboratories ing. “Visiting” general committee members, European Medicines EUCAST has two loosely constructed networks of microbiology 20,000 Agency (EMA) representatives and/or ECDC representatives at- laboratories with particular expertise and training in EUCAST anti- tended several meetings. Two groups from pharmaceutical com- microbial susceptibility testing for bacteria and fungi respectively. 10,000 panies presented to the committee; one provided data on a new EUCAST Network Laboratories, listed on the EUCAST website, are 0 agent, and the other discussed proposals for assessing treat- committed to help develop, validate and troubleshoot EUCAST May July April June March August ment endpoints other than those used conventionally for PK-PD. methods and/or to help train and educate other laboratories in October January February December November In 2017 Christian Giske was the chairman, Rafael Cantón was the EUCAST methods. These laboratories also play an important role September clinical data coordinator, John Turnidge was the scientific secretary in the development of improved methods and/or assist clinical and Gunnar Kahlmeter was the technical data coordinator. Regular breakpoint development by providing MIC datasets. steering committee members were Alasdair MacGowan (United Kingdom), Gerard Lina (France), Sören Gatermann (Germany), EUCAST breakpoints Christoffer Lindemann (Norway), and Johan Mouton (Netherlands). Version 8.0 of the MIC and zone diameter breakpoint tables for Breakpoints were published for some less commonly isolated EUCAST consultations bacteria and QC tables were published on the EUCAST website in organisms, Aeromonas spp. and Plesiomonas spp. Among older Many of the EUCAST documents on the website were updated in 2017 EUCAST General Committee January 2018. agents, macrolide breakpoints for Haemophilus influenzae were re- and this is an ongoing process. Rationale documents, giving back- The annual open meeting for national representatives on the gener- Breakpoints for new agents are set by EUCAST as part of the moved (after general consultation), revised breakpoints were pub- ground data and providing the rationale for EUCAST breakpoints, con- al committee was held during ECCMID, where the preceding year’s marketing authorization process by the EMA. In the past year break- lished for ticarcillin, ticarcillin-clavulanate and cefepime. Revision tinue to be developed. EUCAST expert rules are being updated by the activities and future plans were reviewed. The general committee points were updated for ceftaroline and breakpoints for ceftolozane- is ongoing for carbapenems, aminoglycosides, and tigecycline. steering committee. Proposed changes to intrinsic resistance ta- representatives on the steering committee were Arjana Tambic´- tazobactam and Pseudomonas aeruginosa were added. The break- bles were accepted following public consultation and then released Andraševic´ from Croatia and Deniz Gür from Turkey. points for several other agents are in the process of being evaluated. EUCAST disk diffusion method on the website. A review of the EUCAST guidelines on the detection Studies are undertaken at the EUCAST development laboratory of resistance mechanisms was also completed and published (Växjö, Sweden) in collaboration with EUCAST network laborato- online. A summary of consultations can be found on the website ries to develop EUCAST susceptibility testing methods. Ongoing www.eucast.org/documents/consultations/. All EUCAST documents projects include disk diffusion methods and zone diameter break- are freely available on the EUCAST website. points for new agents and for organisms currently without recommendations. QC ranges are established for new agents and organ- EUCAST network laboratories isms and older QC ranges may be revised if required. Work on developing the structure of the EUCAST network of laboratories was continued in 2017. These labs have specific expertise EUCAST website and training in EUCAST antimicrobial susceptibility testing (AST) There is a continuous process of updating the website and its con- for bacteria and EUCAST antifungal susceptibility testing (AFST) tents. All significant changes are highlighted in the “News” section methods, respectively. EUCAST network laboratories are commit- on the homepage and a list of all changes is available via the “Web- ted to help develop, validate and troubleshoot EUCAST AST/AFST site changes” link below the contents list. Documents updated this methods and/or to help train and educate other laboratories in year include breakpoint tables, QC tables, SOPs, files listing calibra- EUCAST methods. They also play an important role in improving tion and validation of disk diffusion testing vs. MIC, reading guides methods and/or assisting clinical breakpoint development by pro- and method descriptions, frequently asked questions, compliance viding species-specific MIC datasets. For more information and for of manufacturers and validation documents for MIC and inhibition laboratories interested in participating, please visit the EUCAST zone diameter correlations. Figure 1 provides an overview of the AST network laboratories page under the organization tab on the unique visitors to the EUCAST website, indicating a steady increase EUCAST website. Currently 14 bacterial and 11 mycology laborato- Steering Committee Chair, Christian Giske EUCAST Steering Committee, April 2017 over the years. ries have been adopted in the network.

22 YEARBOOK 2017/2018 SCIENCE YEARBOOK 2017/2018 SCIENCE 23 Antifungal susceptibility testing subcommittees (AFST GC & SC) Subcommittee on antimycobacterial agents 2. A position paper on the challenges in susceptibility testing of 6. A paper describing the pitfalls of using a single MIC measure- The AFST subcommittees continued their work on breakpoints The subcommittee, chaired by Emmanuelle Cambau, was estab- M. tuberculosis. ment applied to PK-PD adjustment of dosing. and methods for antifungal agents. The AFST general subcom- lished early in 2016 with the objectives to develop reference sus- Schön T, Miotto P, Köser CU, Viveiros M, Böttger E, Cambau E. Mycobacterium tubercu- Mouton JW, Muller AE, Canton R, Giske CG, Kahlmeter G, Turnidge J. MIC-based dose mittee met once; during ECCMID 2017 in Vienna. The AFST steer- ceptibility testing method guidelines, to interact with the EUCAST losis drug-resistance testing: challenges, recent developments and perspectives. Clin adjustment: facts and fables. J Antimicrob Chemother 2017; Dec 5. doi: 10.1093/jac/ ing committee met twice; for a one-and-a-half-day meeting and steering committee in the setting of breakpoints for antimycobac- Microbiol Infect. 2017;23(3):154-160. dkx427. [Epub ahead of print] once during ECCMID. Current members include Maiken Cavling terial agents and to define the relevance of molecular testing. The Arendrup (chair), Jesús Guinea (scientific secretary), Joseph work so far has resulted in a publication in Clinical Microbiology 3. A paper describing the results of investigation and analyses of 7. A paper describing the results of investigation and analyses of Meletiadis (data coordinator), Johan Mouton (EUCAST steering and Infection on state-of-the-art susceptibility testing of M. tuber- Kingella related to breakpoint setting. a range of commercial products for measuring colistin MICs. committee representative), Petr Hamal (EUCAST AFST representa- culosis (Schön T, Miotto P, Köser CU, et al. Mycobacterium tuber- Matuschek E, Åhman J, Kahlmeter G, Yagupsky P. Antimicrobial susceptibility testing Matuschek E, Åhman J, Webster C, Kahlmeter G. Antimicrobial susceptibility testing tive from the Czech Republic, 2016 – 2018) and Katrien Lagrou culosis drug-resistance testing: challenges, recent developments of Kingella kingae with broth microdilution and disk diffusion using EUCAST recom- of colistin – evaluation of seven commercial MIC products against standard broth mi- (EUCAST AFST representative from Belgium, 2015 – 2017) followed and perspectives. Clin Microbiol Infect. 2017;23(3):154-160). The mended media. Clin Microbiol Infect. 2017 Jul 29. doi: 10.1016/j.cmi.2017.07.019. crodilution for Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and by Francesco Barchiesi (EUCAST AFST representative from Italy, primary task of the committee currently is the development of a [Epub ahead of print] Acinetobacter spp. Clin Microbiol Infect. 2017 Dec 5. doi: 10.1016/j.cmi.2017.11.020. 2017 – 2019). reference MIC testing method. [Epub ahead of print] The EUCAST AFST worked on evaluating azole screening agars 4. A paper describing the results of investigation and analyses of in a blind multicentre study and selecting appropriate QC strains Subcommittee on wild type MIC distributions and Aerococcus related to breakpoint setting. 8. A summary of the planned approach to breakpoint setting for for quality control, both with the aim of simplifying routine testing. epidemiological cut-off values (ECOFFs) Carkaci D, Nielsen XC, Fuursted K, Skov R, Skovgaard O, Trallero EP, Lienhard R, Åh- veterinary antimicrobials by VetCAST The results of the study were published in the Journal of Antimicro- The subcommittee, chaired by Gunnar Kahlmeter, was established man J, Matuschek E, Kahlmeter G, Christensen JJ Aerococcus urinae and Aerococcus Toutain PL, Bousquet-Mélou A, Damborg P, Ferran AA, Mevius D, Pelligand L, Veldman KT, bial Chemotherapy (2017;72(12):3325-3333), and a method docu- early in 2016 with the remit to define standards for MIC distribu- sanguinicola: susceptibility testing of 120 isolates to six antimicrobial agents using Lees P. En Route towards European clinical breakpoints for veterinary antimicrobial ment is being prepared. Moreover spectrophotometer readings of tions required for ECOFF calculation, to define the methods used disk diffusion (EUCAST), Etest, and broth microdilution techniques. Open Microbiol J. susceptibility testing: a position paper explaining the VetCAST approach. Front Micro- Aspergillus microdilution trays have been evaluated and appear to set ECOFFs and to define the conditions for their revision. The 2017;11:160-166. doi: 10.2174/1874285801711010160. eCollection 2017. biol. 2017;8:2344. promising provided a 95% growth inhibition endpoint is adopted subcommittee finalized a proposal on how to accept MIC distribu- (Meletiadis J, Leth Mortensen K, Verweij PE, Mouton JW, Arendrup tions (www.eucast.org/mic_distributions_and_ecoffs/) and on how 5. A paper describing the issues around the susceptibility test- 9. A published proposal from the EUCAST steering committee on MC. Clin Microbiol Infect. 2017; 23(2):98-103). Furthermore visual, to define tentative and established ECOFFs. The SOP (10.0) has ing of colistin. the planned revision of the definition of ‘Intermediate’. spectrophotometric, colorimetric and agar dilution assays are un- now been published. Giske CG, Kahlmeter G. Colistin antimicrobial susceptibility testing – can the slow and Kahlmeter G, EUCAST steering committee. EUCAST proposes to change the definition der evaluation for echinocandin AST. A broth microdilution method challenging be replaced by the rapid and convenient? Clin Microbiol Infect. 2017 Oct and usefulness of the susceptibility category 'Intermediate'. Clin Microbiol Infect. is under development for Trichophyton rubrum. Subcommittee on antimicrobial susceptibility testing by whole 21. pii: S1198-743X(17)30569-4. doi: 10.1016/j.cmi.2017.10.007. [Epub ahead of print] 2017;23(12):894-895. As part of the regular review of EUCAST documents, the posa- genome sequencing (WGS) conazole rationale documents for Candida and Aspergillus have Following the successful first edition of the role of WGS in suscep- been reviewed and amalgamated. This included a breakpoint tibility testing, a review has commenced because this is a rapidly change for Candida albicans. evolving field.

Veterinary subcommittee on antimicrobial susceptibility testing Publications in 2017 (VetCAST) EUCAST published or contributed to nine publications in 2017, two The subcommittee, chaired by Dik Mevius, was established at of the most important of which were on the problems of testing ECCMID in 2015 and is a standing committee, which deals with all colistin and on the pitfalls of applying a single MIC measurement in aspects of breakpoint setting and antimicrobial susceptibility test- therapeutic drug monitoring. ing related to veterinary use of antimicrobial agents. VetCAST received funding in October from the call for transnational networks/ 1. EUCAST’s contribution to an ESCMID survey on selective (cas- working groups within the Joint Programming Initiative on Anti- cade reporting). microbial Resistance (4th joint call, JPIAMR). A position paper on Pulcini C, Tebano G, Mutters NT, Tacconelli E, Cambau E, Kahlmeter G, Jarlier V; EUCIC- the proposed VetCAST approach to the setting of breakpoints was ESGAP-EUCAST selective reporting working group. Selective reporting of antibiotic sus- developed and published (Toutain et al, Frontiers of Microbiology, ceptibility test results in European countries: an ESCMID cross-sectional survey. Int J 2017;8:2344). Antimicrob Agents. 2017;49(2):162-166.

The antifungal susceptibility testing subcommittee, April 2017

The VetCAST subcommittee and meeting attendees, April 2017

24 YEARBOOK 2017/2018 SCIENCE YEARBOOK 2017/2018 SCIENCE 25 European Committee on Infection Control (EUCIC) Infection Prevention & Control: an ESCMID priority! www.escmid.org/eucic

Evelina Tacconelli with ECDC. This will be a cornerstone for disseminating and harmo- important updates on epidemiology, microbiology and prevention. EUCIC Chair nizing infection prevention and control training and education in Lastly we would like to thank Nancy Gerits from the ESCMID offi ce, [email protected] Europe. who has helped signifi cantly with all EUCIC activities. EUCIC members were also actively involved in providing pro- Nico T. Mutters EUCIC and WHO posals for this year’s ECCMID. Infection control education workshops EUCIC Scientifi c Coordinator The World Health Organization founded the Global Infection Pre- and symposia have been highlighted in the ECCMID programme. [email protected] vention and Control (GIPC) Network. Through various actions, it We are aware that there is plenty to do and we look forward to enhances local, national and international collaboration and sup- making further progress with all our partners against infections in Alex W. Friedrich ports the WHO member states’ efforts for infection prevention and 2018. Suggestions and contributions are very welcome! Feel free EUCIC Clinical Coordinator control. EUCIC became an offi cial member of the GIPC Network and to contact us at any time at [email protected] [email protected] Nico Mutters was appointed as liaison offi cer for EUCIC. With a com- mentary in the Lancet Global Health, the GIPC network highlights the global infection prevention and control priorities. Membership of this network will strengthen the cooperation between WHO and EUCIC training EUCIC. We are pleased to announce that the European Committee on In- fection Control (EUCIC) has made substantial progress over the EUCIC internally past year. The EUCIC Infection Prevention and Control Certifi cate EUCIC has elected a new advisory board chair: Vincent Jarlier from – European Training Programme has been launched and, by Janu- the Pitié-Salpêtrière Hospital in Paris, France, and had some regu- ary 2018, the envisaged 15 trainees had already registered for the lar changes in the steering committee (SC). Jesús Rodríguez-Baño full programme. For the fi rst time in Europe, the EUCIC Infection (Spain) and Herman Goossens (Belgium) left the EUCIC SC at the Prevention and Control Certifi cate will integrate courses at an in- end of their terms. They were replaced by elected members Anders ternational level with national courses in selected EUCIC excellence Johansson (Sweden) and Elisabeth Presterl (Austria). Evelina Tac- centres, creating a network of faculty and trainees in different Eu- conelli and Alex Friedrich were confi rmed as EUCIC chair and clini- ropean regions. This will enable the trainees to acquire European cal coordinator, respectively. competence in the fi eld of infection prevention and control. EUCIC cooperated with the COMBACTE-MAGNET consortium In addition we are delighted to announce that the European and helped map surveillance systems throughout Europe. See the Centre for Disease Control (ECDC) will contribute to our training pro- published paper for detailed information (Núñez-Núñez, M. et al., gramme. ECDC’s contribution will be in the areas of epidemiology, CMI2017 Jul 24. pii: S1198-743X(17)30385-3; www.ncbi.nlm.nih. data analysis and surveillance and through the provision of ob- gov/pubmed/28750921). serverships and speakers for several of the modules. EUCIC, ESGAP and EUCAST conducted a European survey ex- The training programme started in February 2018 in Gron- ploring in which countries selective reporting of antibiotic sus- ingen, Netherlands, with the basic and compulsory module. Ad- ceptibility testing results had already been implemented and how vanced modules and observerships follow in 2018 and 2019 in it had been organized. For more details see the published survey selected centres throughout Europe (including Paris, Utrecht, (Pulcini, C. et al., Int J Antimicrob Agents, 2017 Feb;49(2):162-166; Freiburg, Ljubljana, Geneva and Vienna; see Figure 1). Finally the www.ncbi.nlm.nih.gov/pubmed/28093208). programme is complemented with e-learning and local modules, Furthermore EUCIC contributed to other publications on train- Figure 1. which represent in-house expertise and teach country-specifi c ing in infection prevention and control (www.nvmm.nl/ntmm/ Overview of the aspects. For more information check this link: www.escmid.org/ artikeloverzicht/september-2017/thema-onderwijs-en-opleiding- different module research_projects/eucic/training_programme/. europese-compententie/) and on resource needs for antibiotic locations Advanced & basic stewardship teams (www.ncbi.nlm.nih.gov/pubmed/28778544). Local EUCIC UEMS working group The EUCIC implementation working group fi nished a survey Observerships Nicola Petrosillo, Jean-Paul Stahl, Davorka Dusek, Truls Leegard, providing an overview of major limitations in the implementation Hilpi Rautelin of infection prevention and control measures against the spread The Union Européenne des Médecins Spécialistes (UEMS) council of multidrug-resistant Gram-negative bacteria among hospital pa- approved the implementation of a multidisciplinary joint commit- tients. The project will be presented at this year’s ECCMID. tee (MJC) on infection control on the initiative of EUCIC, UEMS in- Our new communication offi cers Gabriel Birgand (United King- fectious diseases and UEMS medical microbiology. The goal is to dom) and Constantinos Tsioutis (Cyprus) have increased EUCIC’s contribute to reaching an agreement on European standards for internet and social media presence. They have also provided re- medical education and training in infection control in collaboration views of important infection control conferences and papers with

26 YEARBOOK 2017/2018 SCIENCE YEARBOOK 2017/2018 SCIENCE 27 Emerging infections task force (EITaF) 2017 Publications

“EITaF tackles the threat of emerging infections, “Our journal CMI and our medical guidelines providing guidance on identification, diagnosis lead the way, supported by the significant and treatment and ensures this knowledge internet and social media presence, to is evaluated and communicated effectively.” make ESCMID publications easily accessible and increasingly effective.” Nicola Petrosillo, Eskild Petersen Co-chairs of ESCMID’s Murat Akova emerging infections taskforce ESCMID Publications and Communications Officer [email protected]

In response to an increasing medical need to react quickly to new EITaF’s outcomes in 2017 With the increasing success of our journal Clinical Microbiology ESCMID publications emerging and re-emerging infectious threats, ESCMID’s executive • EITaF published its first article in Clinical Microbiology and In- and Infection (CMI), and the appointment of a new guidelines di- For the second year in a row, we are featuring a list of all scien- committee (EC) established the emerging infections task force fection entitled “ESCMID Emerging Infections Task Force Expert rector, we are continuing our efforts to increase our publication tific publications resulting from ESCMID’s activities over the past (EITaF) in March 2017. The taskforce is headed by Nicola Petrosillo Panel. Emerging infections – an increasingly important topic.” output. Ensuring the availability of ESCMID’s medical guidelines year. This comprehensive list includes medical guidelines, papers (Italy) and Eskild Petersen (Denmark/Oman) and consists of a Petersen E, Petrosillo N, Koopmans M. and the EITaF Expert Panel. will no doubt affect treatment decisions in Europe and, through on research financed through ESCMID’s research grants and study panel of experts who have both knowledge and access to labora- Clin Microbiol Infect. 2017 Nov 15. pii: S1198-743X(17)30641-9. our collaboration with partner societies, worldwide. In this way, we group grants as well as publications by the society’s study groups tories equipped with state of the art technologies able to provide doi: 10.1016/j.cmi.2017.10.035. The team expects to publish hope to maintain our contribution to improving patients’ lives. and committees, including EUCIC and EUCAST. We recorded nearly a rapid response to outbreaks (including e.g. rapid analysis of any many more. 100 publications in ESCMID’s name over the past year. specimen and assistance in outbreak investigations, for instance • Since its establishment, EITaF has shared 27 news items about Society journals You can help us be more efficient in tracking these publica- through the ECDC European Medical Corps). emerging infections on the ESCMID website. The purpose of the In 2017 ESCMID transferred the ownership of New Microbes and tions by clearly acknowledging ESCMID’s role in your publication news service is to provide ESCMID members with a single source New Infections (NMNI) to its publisher Elsevier, focusing attention and by informing ESCMID’s Publications and Medical Guidelines EITaF’s expert panel consists of 13 members. Together these experts: of news gathered from many other sources, including from WHO, primarily on the success of its main journal Clinical Microbiology Manager when your manuscript is published. The undeniable re- • provide ESCMID members with up-to-date information on out- ECDC, ProMED, IDSA etc. Aside from links to the original source, and Infection (CMI). For his contribution and services relating to ward is more visibility for your work, as it will be announced on our breaks of epidemic or pandemic potential, or outbreaks posing these news items may also contain a short comment placing the NMNI, ESCMID sincerely thanks Michel Drancourt. website and social channels. a threat to individuals travelling to an outbreak area. news into a wider context. The outbreak news link is directly ac- As a result of the continued dedication and hard work of Editor- • provide regular updates to the ESCMID EC on emerging infec- cessible on ESCMID’s homepage. in-Chief Leonard Leibovici, the profile of CMI has risen considerably tions, including threat evaluation. since he took over the journal. His successful efforts are reflected • are expanding the group of experts (clinicians and microbiolo- in the rise of the impact factor from 4.575 to 5.292. CMI continues gists) who can help evaluate emerging infection threats and pro- to improve its timelines and attractiveness, as evidenced by the vide guidance on their identification, diagnosis and treatment. recent launch of the new CMI website. All relevant figures about the • provide background material on emerging threats through re- EITaF’s Expert Panel Journal from last year can be found in the message from the Editor- Publication Subcommittee views and position papers. Kantele Anu, Helsinki, Finland in-Chief on the following pages. Murat Akova, Ankara, Turkey, Chair • organize workshops on emerging infections in collaboration with Nick Beeching, Liverpool, United Kingdom Mario Poljak, Ljubljana, Slovenia ESCMID study groups. Antonino Di Caro, Rome, Italy Medical Guidelines Leonard Leibovici, Tel Aviv, Israel • stimulate research on emerging infections, including surveil- Over the past year, drafting groups were working diligently on the lance and diagnostics. Effrossyni Gkrania-Klotsas, Cambridge, United Kingdom ongoing guidelines on the management and decolonization of mul- Fiona Macnab, London, United Kingdom Rebekka Kohlmann, Leverkusen, Germany tidrug-resistant Gram-negative infections as well as on the treat- Emma Bruun, Oxford, United Kingdom Marion Koopmans, Rotterdam, Netherlands ment of Staphylococcus aureus bacteremia. In addition, two guide- Poh-Lian Lim, Singapore, Singapore lines, the management of Aspergillus disease and the prevention Rogelio López-Vélez, Madrid, Spain of C. difficile infections in acute healthcare settings are nearing publication. Alemka Markotic, Zagreb, Croatia We were sad to see William Hope, our medical guidelines di- Laurent Poirel, Fribourg, Switzerland rector since 2014, leave his position and thank him for his enthusi- John Rossen, Groningen, Netherlands asm, motivation and efforts in bringing ESCMID medical guidelines Ymkje Stienstra, Groningen, Netherlands up to speed with the current guideline requirements. We whole- Merete Storgaard, Aarhus, Denmark heartedly welcome his successor, Luigia Scudeller, ESCMID Medical Guidelines Director as of January 1 2018, to the ESCMID family and look forward very much to working with her. Her guidelines report can be found on page 33.

Eskild Petersen Nicola Petrosillo

28 YEARBOOK 2017/2018 SCIENCE YEARBOOK 2017/2018 PUBLICATIONS 29 CMI Editorial Board Clinical Microbiology and Infection Editor-in-Chief Leonard Leibovici, Tel-Aviv, Israel Associate Editor-in-Chief Gilbert Greub, Lausanne, Switzerland Associate Editors Franz Allerberger, Vienna, Austria “Due to our continued efforts in 2017, the number Guido Antonelli, Rome, Italy of submissions and the efficiency with which we Emmanual Bottieau, Antwerp, Belgium reached a decision on them increased and we were William Couet, Poitiers, France Sally Cutler, London, United Kingdom rewarded with an impact factor of 5.292. We hope Inge Gyssens, Nijmegen, Netherlands to continue this trend now that the new ‘how to’ Angela Huttner, Geneva, Switzerland series, the re-emergence of themed issues and the Laurent Kaiser, Geneva, Switzerland Andre Kalil, Omaha, USA new CMI website are implemented.” Mariska Leeflang, Amsterdam, Netherlands Leonard Leibovici Gerard Lina, Lyon, France CMI Editor-in-Chief Mical Paul, Haifa, Israel [email protected] Celine Pulcini, Nancy, France Jesús Rodríguez Baño, Seville, Spain Emmanuel Roilides, Thessaloniki, Greece Clinical Microbiology and Infection (CMI) publishes original re- Website Panayotis Tassios, Athens, Greece search and review articles to assist physicians and microbiologists The CMI journal website has been redesigned. The new user-friend- in their management of patients and the prevention of infectious ly look, starting with the February 2018 issue, was designed to im- diseases. We aim to promote the use of good methods in basic and prove navigation and the experience of authors and readers alike. clinical research, and to publish interesting and thought-provoking We also predict this will increase article submissions to CMI. material with the potential to change clinical practice. We welcome the feedback of all readers and ESCMID members. Please write to our editorial office, Julia Friedman, with any com- Submissions ments or queries: [email protected]. 2017 saw a 14% increase in the number of submissions compared to 2015 (Fig. 1). We have also shortened the time from submission to a decision on revision to an average of 29 days in 2017 (32 days in 50 Figure 2. 2016, 41 days in 2015) and from submission to rejection after peer- Number of days 45 review to 26 days in 2017 (28 days in 2016, 45 days in 2015, Fig. 2). from submission 40 to final decision Impact factor 2015 2300 Figure 1. 35 Our 2016 impact factor was 5.292 compared with 4.575 in 2015. 2016 Total manuscript 30 2017 submissions Reviews 2200 25 We have begun a new series of reviews: ‘How to...’ articles are an 20 in-depth explanation on how to do things that are of interest to our 15 readers. These topics of interest might be new laboratory techniques 2100 in the clinical or research laboratory, new programmes (e.g. how 10 to establish an antibiotic stewardship effort in a hospital in which 2000 5 there is none) or new data analyses (e.g. how to use interrupted 0 time-series analysis). We will also continue to have themed issues. NMNI

1900 Reject As in past years, these issues consist of 3 – 5 narrative reviews Accept addressing the different aspects of one topic. To serve as guest Revision editor of a themed issue, please contact me with an outline of the 1800 Immediate Reject proposed topic, including the names of proposed authors for each Accept Immediate Immediate reject reject Immediate to referral with 2017 Outside journal scope 2015 of the reviews. 2016

30 YEARBOOK 2017/2018 PUBLICATIONS YEARBOOK 2017/2018 PUBLICATIONS 31 Medical Guidelines www.escmid.org/guidelines Check out the April issue, freely available for ECCMID!

CMI “It is a great responsibility to be ESCMID guidelines director. The great challenge is to CLINICAL MICROBIOLOGY produce valid and useful documents based on a stringent ethical policy: to deliver the AND INFECTION best available care to patients in sustainable Editor-in-Chief: Leonard Leibovici health systems in Europe and worldwide.”

I) is a monthly Luigia Scudeller Clinical Microbiology and Infection (CM ESCMID Guidelines Director publication of the European Society of Clinical Microbiology [email protected] and Infectious Diseases and publishes peer-reviewed papers that present basic and applied research relevant to therapy and diagnostics in the elds of microbiology, infectious diseases, It is an honour to have been appointed as Medical Guidelines Di- At the end of 2017 my predecessor William Hope handed ESCMID’s rector of ESCMID. I am both grateful to the EC for granting me this medical guidelines portfolio over to me. I would like to thank him virology, parasitology, immunology and epidemiology. opportunity and fully aware of the great responsibility that comes sincerely for all his work over the years and for his support in help- with this position. Together with the EC, our medical guideline sub- ing me get acquainted with the portfolio. Stay up to date on outbreak news and visit the ESCMID Emerging Infections committee, our study groups and our drafting groups, I am sure Task Force (EITaF) at www.clinicalmicrobiologyandinfection.com we can produce methodologically accurate documents, relevant to Looking forward clinical practice and public health in ID and CM. Building on the experience of my predecessor, and in agreement READ FOR FREE ONLINE with the Executive Committee, we have set the following priorities 2017 in a nutshell to further develop the global role of ESCMID in developing guide- Top most cited articles: Key papers, selected by our Editor-in-Chief: Last year saw the publication of three guidelines and the continu- lines in CM and ID. We plan to strengthen the cooperation with ation of ongoing medical guideline projects, two of which are now ESCMID’s study groups, establish new partnerships with other sci- ᕃ ᕃ European society of clinical microbiology and The role of whole genome sequencing in near publication; the management of Aspergillus disease and the entifi c networks, implement certifi ed training courses for CM or ID infectious diseases: Update of the treatment antimicrobial susceptibility testing of bacteria: prevention of C. diffi cile infection in acute healthcare settings. professionals interested in the many and complex issues involved guidance document for Clostridium dicile report from the EUCAST Subcommittee The ESCMID guidelines on spondylodiscitis, osteomyelitis and in medical guidelines development, and prioritize upcoming (up- infection ᕄ Observational studies examining patient prosthetic joint infections and guidelines for the management of dated and new) guidelines. In order to achieve these exciting and challenging objectives, I ᕄ Rapid spread of emerging Zika virus in the management in infectious diseases infections due to non-tuberculous mycobacteria (in conjunction with IDSA, ATS and ERS) are also scheduled for publication in 2018. look forward to a fruitful collaboration with all of you. So if you have Pacic area ᕅ Clinical considerations for optimal use of ESCMID also endorsed three guidelines: the ISF/ESCMID guideline any ideas, suggestions or comments, I am happy to be contacted ᕅ ESCMID guidelines for the management of the polymyxins: A focus on agent selection on the management of sepsis, and septic shock, the ERS/ESICM/ by email. the infection control measures to reduce and dosing ESCMID international guidelines on HAP/VAP and the ERS/ESCMID transmission of multidrug-resistant European bronchiectasis guidelines. For a full overview of current ᕆ Gram-negative bacteria in hospitalized patients Fair reporting of study results medical guidelines, please see the table below. ᕇ ᕆ EUCAST expert rules in antimicrobial Ensuring universal access to old antibiotics: a susceptibility testing critical but neglected priority Guideline Owner Status Management of sepsis and septic shock ISF/ESCMID Published in March 2017 in ICM and CCM ᕈ Use of nebulized antimicrobials for the ᕇ The dicult-to-control spread of International guidelines on HAP/VAP ERS/ESICM/ESCMID Published in September 2017 carbapenemase producers among treatment of respiratory infections in invasively European bronchiectasis guidelines ERS/ESCMID Published in September 2017 Enterobacteriaceae worldwide mechanically ventilated adults: a position paper from the European Society of Clinical Diagnosis and management of Aspergillus diseases ESCMID/ECMM/ERS (EFISG) Accepted for publication in 2018 Microbiology and Infectious Diseases C. diffi cile infection control measures – update ESCMID (ESGCD) Submitted for publication in 2018 Guidelines on spondylodiscitis, osteomyelitis and prosthetic joint infections ESCMID Publication planned in 2018 ᕉ How to: Establish and run a stool bank Management of infections due to non-tuberculous mycobacteria IDSA/ATS/ERS/ESCMID Publication planned in 2018 Treatment of multidrug-resistant Gram-negative bacteria ESCMID Ongoing 2018 Visit the new-look website at Decolonization of multidrug-resistant Gram-negative bacteria ESCMID Ongoing 2018 Clinical practice guideline on S. aureus bacteraemia IDSA/ESCMID Ongoing 2018 www.clinicalmicrobiologyandinfection.com Rituals and behaviours in the OR to reduce infection ESCMID/HIS Proposal approved Zygomycosis ESCMID/ECMM Proposal approved

32 YEARBOOK 2017/2018 PUBLICATIONS YEARBOOK 2017/2018 PUBLICATIONS 33 Diagnosis and management of Aspergillus diseases: executive ESGBIS ESCMID publications summary of the 2017 ESCMID-ECMM-ERS guideline A Prospective Multicentre Study of the Epidemiology and Outcomes Ullmann A.J., Aguado J.M., Arikan-Akdagli S., Denning D.W., Groll A.H., Lagrou K., of Bloodstream Infection in Cirrhotic Patients. Lass-Flörl C., Lewis R.E., Munoz P., Verweij P.E., Warris A., Ader F., Akova M., Arendrup Michele Bartoletti, Maddalena Giannella, Russell Lewis, Paolo Caraceni, Sara Tedeschi, M.C., Barnes R.A., Beigelman-Aubry C., Blot S., Bouza E., Brüggemann R.J.M., Buch- Mical Paul, Christoph Schramm, Tony Bruns, Manuela Merli, Nazaret Cobos-Trigueros, ESCMID publications MMR and MMRV vaccines. heidt D., Cadranel J., Castagnola E., Chakrabarti A., Cuenca-Estrella M., Dimopoulos G., Elena Seminari, Pilar Retamar, Patricia Muñoz, Mario Tumbarello, Patrizia Burra, Maria Kowalzik F, Faber J, Knuf M. Vaccine. Jul 27. pii: S0264-410X(17)30959-3. doi: Fortun J., Gangneux J.-P., Garbino J., Heinz W.J., Herbrecht R., Heussel C.P. , Kibbler C.C., Torrani Cerenzia, Bruno Barsic, Ester Calbo, Alberto Enrico Maraolo, Nicola Petrosillo, A large survey among European trainees in clinical microbiology 10.1016/j.vaccine.2017.07.051. Klimko N., Kullberg B.J., Lange C., Lehrnbecher T., Löffler J., Lortholary O., Maertens J., Maria Angeles Galan-Ladero, Giampiero D’Offizi, Noa Bar Sinai, Jesus Rodríguez- and infectious disease on training systems and training adequacy: Marchetti O., Meis J.F., Pagano L., Ribaud P., Richardson M., Roilides E., Ruhnke M., San- Baño, Gabriella Verucchi, Mauro Bernardi, Pierluigi Viale On behalf of ESGBIS/ identifying the gaps and suggesting improvements. New perspectives for hexavalent vaccines. guinetti M., Sheppard D.C., Sinkó J., Skiada A., Vehreschild M.J.G.T., Viscoli C., Cornely BICHROME study group Clinical Microbiology and Infection. Clin Microbiol Infect. 2017 Yusuf E, Ong DS, Martin-Quiros A, Skevaki C, Cortez J, Dedic´ K, Maraolo AE, Dušek D, Obando-Pacheco P, Rivero-Calle I, Gómez-Rial J, Rodríguez-Tenreiro Sánchez C, O.A. Clin Microbiol and Infect. 12 March 2018. In Press http://www.clinicalmicrobiolog- Aug 14. pii: S1198-743X(17)30426-3. doi: 10.1016/j.cmi.2017.08.001. Maver PJ, Sanguinetti M, Tacconelli E; Trainee Association of the European Society of Martinón-Torres F. Vaccine. Jul 1. pii: S0264-410X(17)30860-5. doi: 10.1016/j.vaccine. yandinfection.com/article/S1198-743X(18)30051-X/fulltext Clinical Microbiology and Infectious Diseases (ESCMID). Eur J Clin Microbiol Infect Dis. 2017.06.063. ESGCIP 2017;36(2):233-242. doi: 10.1007/s10096-016-2791-9 Use of Nebulized Antimicrobials for the Treatment of Respiratory Norovirus vaccines under development. Publications from Study Groups Infections in Invasively Mechanically Ventilated Adults: A Position Personal life and working conditions of trainees and young special- Lucero Y, Vidal R, O'Ryan G M. Vaccine. 2017 Jun 28. pii: S0264-410X(17)30830-7. doi: Paper from the European Society of Clinical Microbiology and Infec- ists in clinical microbiology and infectious diseases in Europe: a 10.1016/j.vaccine.2017.06.043. ESGAI tious Diseases. questionnaire survey. The International Anaerobe Quality Assurance Scheme (IAQAS). Rello J, Solé-Lleonart C, Rouby JJ, Chastre J, Blot S, Poulakou G, Luyt CE, Riera J, Palm- Maraolo AE, Ong DS, Cortez J, Dedic´ K, Dušek D, Martin-Quiros A, Maver PJ, Skevaki Progress and challenges in measles and rubella elimination in the Morris T, Copsey-Mawer S, Hughes H; ESCMID Study Group for Anaerobic Infections (ESGAI). er LB, Pereira JM, Felton T, Dhanani J12, Bassetti M, Welte T, Roberts JA. Clin Microbiol C, Yusuf E, Poljak M, Sanguinetti M, Tacconelli E; Trainee Association of the European WHO European Region. Anaerobe. 2017 Dec 6. pii: S1075-9964(17)30205-6. doi: 10.1016/j.anaerobe.2017.10.009. Infect. 2017;23:629-639. doi: 10.1016/j.cmi.2017.04.011. Society of Clinical Microbiology and Infectious Diseases (ESCMID). Eur J Clin Microbiol Datta SS, O’Connor PM, Jankovic D, Muscat M, Ben Mamou MC, Singh S, Kaloumenos T, Infect Dis. 2017;36(7):1287-1295. doi: 10.1007/s10096-017-2937-4 Reef S, Papania M, Butler R. Vaccine, 2017 Jun 23. pii: S0264-410X(17)30829-0. doi: ESGAP ESGFOR 10.1016/j.vaccine.2017.06.042. Forgotten antibiotics: a follow-up inventory study in Europe, the How is post-mortem microbiology appraised by pathologists? Re- ESCMID – an international Europe-based society committed to fos- USA, Canada and Australia. sults from a practice survey conducted by ESGFOR. tering cross-border collaboration and education to improve patient Global polio eradication: Where are we in Europe and what next? Pulcini C, Mohrs S, Beovic B, Gyssens I, Theuretzbacher U, Cars O; ESCMID Study Group Saegeman V, Cohen MC, Alberola J, Ziyade N, Farina C; ESCMID Study Group for Foren- care. Celentano LP, Carrillo-Santisteve P, O’Connor P, Danielsson N, Huseynov S, Derrough T, for Antibiotic Policies (ESGAP), ReAct Working Group on Old Antibiotics. Int J Antimi- sic and Postmortem Microbiology, Cornaglia G, Fernández-Rodríguez A. Eur J Clin Mi- Poljak M, Akova M, Friedrich AW, Rodríguez-Baño J, Sanguinetti M, Tacconelli E, Zinker- Adel Ali K, Butler R, Greco D. Vaccine. 2017 May 3. pii: S0264-410X(17)30516-9. doi: crob Agents. 2017;49(1):98-101. doi: 10.1016/j.ijantimicag.2016.09.029 crobiol Infect Dis. 2017;36(8):1381-1385. doi: 10.1007/s10096-017-2943-6 nagel A. Clin Microbiol Infect. 2017;24(1):1-2. doi: 10.1016/j.cmi.2017.05.024. 10.1016/j.vaccine.2017.04.038. Erratum to ‘Forgotten antibiotics: a follow-up inventory study in Eu- ESGLI Antimicrobial resistance and antibiotic stewardship programs in Vaccination in newly arrived immigrants to the European Union. rope, the USA, Canada and Australia’ A bioinformatics tool for ensuring the backwards compatibility of the ICU: insistence and persistence in the fight against resistance. Prymula R, Shaw J2, Chlibek R, Urbancikova I, Prymulova K. Vaccine. 2017 Jun 8. pii: [International Journal of Antimicrobial Agents 49/1 (2017) 98-101]. Pulcini C, Mohrs Legionella pneumophila typing in the genomic era. A position statement from ESICM/ESCMID/WAAAR round table on S0264-410X(17)30747-8. doi: 10.1016/j.vaccine.2017.05.079. S, Beovic B, Gyssens I, Theuretzbacher U, Cars O; ESCMID Study Group for Antibiotic Gordon M, Yakunin E, Valinsky L, Chalifa-Caspi V, Moran-Gilad J; ESCMID Study Group multi-drug resistance. Policies (ESGAP); ReAct Working Group on Old Antibiotics. Int J Antimicrob Agents. for Legionella Infections. Clin Microbiol Infect. 2017;23(5):306-310. doi: 10.1016/j. De Waele JJ, Akova M, Antonelli M, Canton R, Carlet J, De Backer D, Dimopoulos Comparative incidence dynamics and serotypes of meningitis, bac- 2017;49(4):482. doi: 10.1016/j.ijantimicag.2017.02.006. cmi.2017.01.002 G, Garnacho-Montero J, Kesecioglu J, Lipman J, Mer M, Paiva JA, Poljak M, Roberts teremic pneumonia and other-IPD in young children in the PCV era: JA, Rodriguez Bano J, Timsit JF, Zahar JR, Bassetti M. Intensive Care Med. 2017; Insights from Israeli surveillance studies. Managing responsible antimicrobial use: perspectives across the Genomic investigation of a suspected outbreak of Legionella pneu- 44(2):189-196. doi: 10.1007/s00134-017-5036-1. Ben-Shimol S, Givon-Lavi N, Grisaru-Soen G, Megged O, Greenberg D, Dagan R; Israel healthcare system. mophila ST82 reveals undetected heterogeneity by the present Bacteremia and Meningitis Active Surveillance Group. Vaccine. 2017 Jun 1. pii: S0264- Dyar OJ, Tebano G, Pulcini C; ESGAP (ESCMID Study Group for Antimicrobial steward- gold-standard methods, Denmark, July to November 2014. Vaccines 410X(17)30707-7. doi: 10.1016/j.vaccine.2017.05.059. shiP). Clin Microbiol Infect. 2017;23(7):441-447: 10.1016/j.cmi.2017.04.016. Schjørring S, Stegger M, Kjelsø C, Lilje B, Bangsborg JM, Petersen RF, David S, Uldum The crucial role of maternal care providers as vaccinators for preg- SA; ESCMID Study Group for Legionella Infections (ESGLI). Euro Surveill. 2017;22(25). nant women. Safety and perception: What are the greatest enemies of HPV vac- Ensuring universal access to old antibiotics: a critical but neglect- doi: 10.2807/1560-7917.ES.2017.22.25.30558. Vilca ML, Esposito S. Vaccine. 2017 Aug 16. pii: S0264-410X(17)31084-8. doi: 0.1016/j. cination programmes? ed priority. vaccine.2017.08.017. Bonanni P, Zanella B, Santomauro F, Lorini C, Bechini A, Boccalini S. Vaccine. 2017 Jun Pulcini C, Beovic B, Béraud G, Carlet J, Cars O, Howard P, Levy-Hara G, Li G, Nathwani ESGMI 10. pii: S0264-410X(17)30730-2. doi: 10.1016/j.vaccine.2017.05.071. D, Roblot F, Sharland M. Clin Microbiol Infect. 2017; 23(9):590-592. doi: 10.1016/j. Multi-center evaluation of one commercial and 12 in-house real- Focusing on the implementation of 21st century vaccines for adults. cmi.2017.04.026. time PCR assays for detection of Mycoplasma pneumoniae. Bonanni P, Bonaccorsi G, Lorini C, Santomauro F, Tiscione E, Boccalini S, Bechini A. Dumke R, Benitez AJ, Chalker V, Gullsby K, Henrich B, Hidalgo-Grass C, Hoogenboezem Vaccine. 2017 Aug 11, pii: S0264-410X(17)31036-8. doi: 10.1016/j.vaccine.2017.07.100. Medical guidelines What is antimicrobial stewardship? T, Kese D, Loens K, Maaskant J, Michael-Gayego A Moses AE, Nir-Paz R, Pas SD, Pereyre Dyar OJ, Huttner B, Schouten J, Pulcini C. Clin Microbiol Infect. 2017;23(11):793-798. S, Petersen RF, Rosenblatt M, van Rossum AMC, Uldum SA, Unger WWJ, Ursi D, Winchell A review of the key factors to improve adult immunization coverage Surviving Sepsis Campaign: International Guidelines for Manage- doi: 10.1016/j.cmi.2017.08.026. JM, Bebear C; ESCMID Study Group for Mycoplasma Infections. Diagn Microbiol Infect rates: What can the clinician do? ment of Sepsis and Septic Shock: 2016. Dis. 2017;88(2):111-114. doi: 10.1016/j.diagmicrobio.2017.03.004. Tan LLJ. Vaccine. 2017 Aug 10. pii: S0264-410X(17)30958-1. doi: 10.1016/j.vaccine. Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky ESGAP inventory of target indicators assessing antibiotic prescrip- 2017.07.050. JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, tions: a cross-sectional survey. ESGS Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishi- Howard P, Huttner B, Beovic B, Beraud G, Kofteridis DP, Pano Pardo J, Schouten J, MRSA infections among patients in the emergency department: a Herpes zoster prevention: A difficult problem to solve. ma S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Pulcini C. J Antimicrob Chemother. 2017; 72(10):2910-2914 European multicentre study. Esposito S, Principi N. Vaccine. Aug 4. pii: S0264-410X(17)31035-6. doi: 10.1016/j. 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34 YEARBOOK 2017/2018 PUBLICATIONS YEARBOOK 2017/2018 PUBLICATIONS 35 EVASG EUCIC-ESGAP-EUCAST Pooled analysis of 899 nosocomial meningitis episodes from Turkey. How to: identify non-tuberculous Mycobacterium species using The 26th European Congress of Clinical Microbiology and Infectious Selective reporting of antibiotic susceptibility test results in Euro- Sipahi OR, Nazlı-Zeka A, Tasbakan M, Pullukcu H, Arda B, Yamazhan T, Sipahi H, Ulusoy MALDI-TOF mass spectrometry. Diseases (ECCMID) in Amsterdam, the Netherlands. pean countries: an ESCMID cross-sectional survey. S. Turk J Med Sci. 2017;47:29-33. doi:10.3906/sag-1508-102 Alcaide F, Amlerová J, Bou G, Ceyssens PJ, Coll P, Corcoran D, Fangous MS7, González- Esposito S, Poljak M; ESCMID Vaccine Study Group (EVASG). Hum Vaccin Immunother. Pulcini C, Tebano G, Mutters NT, Tacconelli E, Cambau E, Kahlmeter G, Jarlier V; Álvarez I, Gorton R, Greub G, Hery-Arnaud G, Hrábak J, Ingebretsen A, Lucey B, Marekovi 2017;13(1):151-152. doi: 10.1080/21645515.2016.1227517 EUCIC-ESGAP-EUCAST Selective Reporting Working Group. Int J Antimicrob Agents. Update and new insights in encephalitis. I, Mediavilla-Gradolph C, Monté MR, O’Connor J12, O’Mahony J, Opota O, O’Reilly B, 2017;49(2):162-166. doi: 10.1016/j.ijantimicag.2016.11.014 Mailles A, Stahl JP, Bloch KC. Clin Microbiol Infect. 2017;23(9):607-613. doi: 10.1016/j. Orth-Höller D, Oviaño M, Palacios JJ, Palop B, Pranada AB, Quiroga L, Rodríguez-Tempo- Strategies to develop vaccines of pediatric interest. cmi.2017.05.002. ral D, Ruiz-Serrano MJ, Tudó G, Van den Bossche A4, van Ingen J21, Rodriguez-Sanchez Esposito S, Principi N, European Society Of Clinical Microbiology And Infectious Diseas- B; European Study Group on Genomics and Molecular Diagnosis (ESGMD). Clin Micro- es (ESCMID) Vaccine Study Group (EVASG). Expert Rev Vaccines. 2017;16(2):175-186. Study group contributions to publications An update on bacterial brain abscess in immunocompetent patients. biol Infect. 2017 Nov 22. pii: S1198-743X(17)30643-2. doi: 10.1016/j.cmi.2017.11.012. doi: 10.1080/14760584.2017.1237875 Sonneville R, Ruimy R, Benzonana N, Riffaud L, Carsin A, Tadié JM, Piau C, Revest M, ESGAI Tattevin P. Clin Microbiol Infect. 2017;23(9):614-620. doi: 10.1016/j.cmi.2017.05.004. Real-time genomic investigation underlying the public health Influenza immunization policies: Which could be the main reasons Phenotypic detection of the cfiA metallo-beta-lactamase in Bacte- response to a Shiga toxin-producing Escherichia coli O26:H11 for differences among countries? roides fragilis with the meropenem-EDTA double-ended Etest and the Central nervous system infections: work in progress. outbreak in a nursery. Principi N, Camilloni B, Esposito S; ESCMID Vaccine Study Group (EVASG). Hum Vaccin ROSCO KPC/MBL Confirm Kit. Tattevin P, Pulcini C. Clin Microbiol Infect. 2017;23(9):599-600. doi: 10.1016/j. Moran-Gilad J, Rokney A, Danino D, Ferdous M, Alsana F, Baum M, Dukhan L, Agmon Immunother. 2017 Dec 11:1-9. doi: 10.1080/21645515.2017.1405188. Schwensen SA, Acar Z, Sydenham TV, Johansson ÅC, Justesen US. J Antimicrob Chem- cmi.2017.07.015. V, Anuka E, Valinsky L, Yishay R, Grotto I, Rossen JWA, Gdalevich M. Epidemiol Infect. other. 2017;72(2):437-440. doi: 10.1093/jac/dkw436 2017;145(14):2998-3006. doi: 10.1017/S0950268817001923. EUCAST Management of adult infectious encephalitis in metropolitan France. Antimicrobial susceptibility testing of Kingella kingae with broth mi- ESGBIS Goulenok T1, Buzelé R2, Duval X3, Bruneel F4, Stahl JP5, Fantin B6. Med Mal Infect. Next-generation sequencing applications in clinical bacteriology. crodilution and disk diffusion using EUCAST recommended media. Empiric Therapy With Carbapenem-Sparing Regimens for Blood- 2017;47(3):206-220. doi: 10.1016/j.medmal.2017.01.006. Motro Y, Moran-Gilad J. Biomol Detect Quantif. 2017;14:1-6. doi: 10.1016/j. Matuschek E, Åhman J, Kahlmeter G, Yagupsky P. Clin Microbiol Infect. 2017 Jul 28. pii: stream Infections due to Extended-Spectrum Beta-Lactamase-Pro- bdq.2017.10.002. S1198-743X(17)30403-2. doi: 10.1016/j.cmi.2017.07.019. ducing Enterobacteriaceae: Results From the INCREMENT Cohort. ESGICH Palacios-Baena ZR, Gutiérrez-Gutiérrez B, Calbo E, Almirante B, Viale P, Oliver A, Pin- Multinational retrospective case-control study of risk factors for Microbial Metagenomics Mock Scenario-based Sample Simulation EUCAST proposes to change the definition and usefulness of the tado V, Gasch O, Martínez-Martínez L, Pitout J, Akova M, Peña C, Molina Gil-Bermejo the development of late invasive pulmonary aspergillosis following (M3S3). susceptibility category ”Intermediate”. J, Hernández A12, Venditti M, Prim N, Bou G, Tacconelli E, Tumbarello M, Hamprecht A, kidney transplantation. Motro Y1, Moran-Gilad J2. Clin Microbiol Infect. 2017;24(3):308.e1-308.e4. doi: Kahlmeter G. on behalf of the EUCAST Steering Committee. Clin Microbiol Infect Giamarellou H, Almela M, Pérez F, Schwaber MJ, Bermejo J23, Lowman W, Hsueh PR, Francisco López-Medrano, Mario Fernández-Ruiz, José Tiago Silva, Peggy L. Carver, 10.1016/j.cmi.2017.08.006. 2017;23(12): 894–895. doi: 10.1016/j.cmi.2017.08.015 Paño-Pardo JR, Torre-Cisneros J, Souli M, Bonomo RA, Carmeli Y, Paterson DL, Pascual Christian van Delden, Esperanza Merino, María José Pérez-Saez, Milagros Montero, Á, Rodríguez-Baño J; Spanish Network for Research in Infectious Diseases (REIPI)/ Julien Coussement, Milene de Abreu Mazzolin, Carlos Cervera, Lidia Santos, Nuria ESGMYC Antimicrobial susceptibility testing of colistin – evaluation of seven European Study Group of Bloodstream Infections and Sepsis (ESGBIS)/INCREMENT Sabé, Anne Scemla, Elisa Cordero, Leónidas Cruzado-Vega, Paloma Leticia Martín- Joint efforts urgently needed at times of emerging tuberculosis drug commercial MIC products against standard broth microdilution for Group. Clin Infect Dis. 2017;65(10):1615-1623. doi: 10.1093/cid/cix606. Moreno, Óscar Len, Eddison Rudas, Alfredo Ponce de León, Mariano Arriola, Ricardo resistance. Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Lauzurica, Miruna D. David, Claudia González-Rico, Fernando Henríquez-Palop, Jesús Allerberger F, Cambau E, Lange C. Clin Microbiol Infect. 2017;23(3):129-130. Doi: and Acinetobacter spp. ESGBOR Fortún, Marcio Nucci, Oriol Manuel, José Ramón Paño-Pardo, Miguel Montejo, Anto- 10.1016/j.cmi.2016.08.023 Matuschek E, Åhman J, Webster C, Kahlmeter G. Clin Microbiol Infect. 2017 Dec 5. pii: Corrigendum: There is inadequate evidence to support the division nio Vena, Beatriz Sánchez-Sobrino, Auxiliadora Mazuecos, Julio Pascual, Juan Pablo S1198-743X(17)30667-5. doi: 10.1016/j.cmi.2017.11.020. of the genus Borrelia. Horcajada, Thanh Lecompte, Asunción Moreno, Jordi Carratalà, Marino Blanes, Do- Mycobacterium tuberculosis drug-resistance testing: challenges, Margos G, Marosevic D, Cutler S, Derdakova M, Diuk-Wasser M, Emler S, Fish D, Gray J, mingo Hernández, Erick Alejandro Hernández-Méndez, María Carmen Fariñas, Manuel recent developments and perspectives. Mycobacterium tuberculosis drug-resistance testing: challenges, Hunfeld KP, Jaulhac B, Kahl O, Kovalev S, Kraiczy P, Lane RS, Lienhard R, Lindgren PE, Perelló-Carrascosa, Patricia Muñoz, Amado Andrés, José María Aguado. Clin Microbiol Schön T, Miotto P, Köser CU, Viveiros M, Böttger E, Cambau E. Clin Microbiol Infect. recent developments and perspectives. Ogden NH17, Ornstein K, Rupprecht T, Schwartz I, Sing A, Straubinger RK, Strle F, Voor- Infect. 2017;24(2):192-198. doi: 10.1016/j.cmi.2017.06.016. 2017;23(3):154-160. Doi: 10.1016/j.cmi.2016.10.022 Schön T, Miotto P, Köser CU, Viveiros M, Böttger E, Cambau E. Clin Microbiol Infect. douw M, Rizzoli A, Stevenson B, Fingerle V. Int J Syst Evol Microbiol. 2017;67(6):2073. 2017;23(3):154-160. doi: 10.1016/j.cmi.2016.10.022 doi: 10.1099/ijsem.0.002100. ESGITM Consensus numbering system for the rifampicin resistance-associ- Post-traumatic stress disorder in internally displaced people of ated rpoB gene mutations in pathogenic mycobacteria. Aerococcus urinae and Aerococcus sanguinicola: Susceptibility ESGCD Colombia: An ecological study. Andre E, Goeminne L, Cabibbe A, Beckert P, Kabamba Mukadi B, Mathys V, Gagneux Testing of 120 Isolates to Six Antimicrobial Agents Using Disk Diffu- Microbiological factors affecting Clostridium difficile recurrence. Lagos-Gallego M, Gutierrez-Segura JC, Lagos-Grisales GJ, Rodriguez-Morales AJ. Travel S, Niemann S, Van Ingen J, Cambau E. Clin Microbiol Infect. 2017;23(3):167-172. Doi: sion (EUCAST), Etest, and Broth Microdilution Techniques. Chilton CH, Pickering DS, Freeman J. Clin Microbiol Infect. 2017 Dec 2. pii: S1198- Med Infect Dis. 2017;16:41-45. doi: 10.1016/j.tmaid.2017.02.008. 10.1016/j.cmi.2016.09.006 Carkaci D, Nielsen XC, Fuursted K, Skov R, Skovgaard O, Trallero EP, Lienhard R, Åhman 743X(17)30648-1. doi: 10.1016/j.cmi.2017.11.017. J, Matuschek E, Kahlmeter G, Christensen JJ. Open Microbiol J. 2017;11:160-166. doi: ESGMD EUCIC 10.2174/1874285801711010160. ESGIAI Whole-genome sequencing and comparative genomic analysis of The Methodology of Surveillance for Antimicrobial Resistance and The Not-So-Good Prognosis of Streptococcal Periprosthetic Joint Bordetella pertussis isolates from the 2007 – 2008 epidemic in Healthcare-Associated Infections in Europe (SUSPIRE): A System- MIC-based dose adjustment: facts and fables. Infection Managed by Implant Retention: The Results of a Large Israel. atic Review of Publicly Available Information. Mouton JW, Muller AE, Canton R, Giske CG, Kahlmeter G, Turnidge J. J Antimicrob Chem- Multicenter Study. Octavia S, Wu SZ, Kaur S, Valinsky L, Marva E, Moran-Gilad J, Lan R. J Infect. Núñez-Núñez M, Navarro MD, Palomo V, Rajendran NB, Del Toro MD, Voss A, Sharland other 2017; Dec 5. doi: 10.1093/jac/dkx427. Lora-Tamayo J, Senneville É, Ribera A, Bernard L, Dupon M, Zeller V, Li HK, Arvieux C, 2017;74(2):204-207. doi: 10.1016/j.jinf.2016.11.012 M, Sifakis F, Tacconelli E, Rodríguez-Baño J; members of EPI-NET, COMBACTE-MAGNET Clauss M, Uçkay I, Vigante D, Ferry T, Iribarren JA, Peel TN, Sendi P, Miksic NG, Rod- and EUCIC group for SUSPIRE. Clin Microbiol Infect. 2017;24(2):105-109. doi: 10.1016/j. 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Op weg naar een multidisciplinaire en internationale opleiding. Lees P. Front Microbiol. 2017;8:2344. doi: 10.3389/fmicb.2017.02344 Ramos A, Giannitsioti E, Jover-Sáenz A, Baraia-Etxaburu JM, Barbero JM, Choong PFM, 10.2217/fmb-2016-0158 Mutters N and Friedrich A. Ned Tijdschr Med Microbiol 2017;25(3):119-122 Asseray N, Ansart S, Moal GL, Zimmerli W, Ariza J; Group of Investigators for Strepto- ESGICH, ESGCIP and EPASG coccal Prosthetic Joint Infection. Clin Infect Dis. 2017;64(12):1742-1752. doi: 10.1093/ Practical issues in implementing whole-genome-sequencing in rou- EUCIC and ESGAP The role of infection models and PK/PD modelling for optimising care cid/cix227. tine diagnostic microbiology. Human resources estimates and funding for antibiotic stewardship of critically ill patients with severe infections. Rossen JWA, Friedrich AW, Moran-Gilad J; ESCMID Study Group for Genomic and teams are urgently needed. 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36 YEARBOOK 2017/2018 PUBLICATIONS YEARBOOK 2017/2018 PUBLICATIONS 37 ESGCIP and ESGNI Quorum sensing inhibition in Pseudomonas aeruginosa biofilms: Eligibility for Key considerations on nebulization of antimicrobial agents to me- new insights through network mining. ESCMID awards, chanically ventilated patients. Pérez-Pérez M, Jorge P, Pérez Rodríguez G, Pereira MO, Lourenço A. Biofouling. Rello J, Rouby JJ, Sole-Lleonart C, Chastre J, Blot S, Luyt CE, Riera J, Vos MC, Monsel 2017;33(2):128-142. doi: 10.1080/08927014.2016.1272104. research grants, A, Dhanani J, Roberts JA. Clin Microbiol Infect. 2017;23(9):640-646. doi: 10.1016/j. cmi.2017.03.018. A network perspective on antimicrobial peptide combination thera- observerships pies: the potential of colistin, polymyxin B and nisin. and mentorships ESGVM and EUCAST Jorge P, Pérez-Pérez M, Pérez Rodríguez G, Pereira MO, Lourenço A.Int J Antimicrob Access to the Society’s journal: En Route towards European Clinical Breakpoints for Veterinary An- Agents. 2017;49(6):668-676. doi: 10.1016/j.ijantimicag.2017.02.012. timicrobial Susceptibility Testing: A Position Paper Explaining the eLibrary and CMI VetCAST Approach. Influence of vancomycin minimum inhibitory concentration on the Toutain PL, Bousquet-Mélou A1, Damborg P, Ferran AA, Mevius D, Pelligand L, Veldman KT, outcome of methicillin-susceptible Staphylococcus aureus left- member- Lees P. Front Microbiol. 2017;8:2344. doi: 10.3389/fmicb.2017.02344. eCollection 2017. sided infective endocarditis treated with antistaphylococcal ship directory Discounts to b-lactam antibiotics: a prospective cohort study by the Internation- al Collaboration on Endocarditis. other journals Publications from recipients of Pericàs JM, Messina JA, Garcia-de-la-Mària C, Park L, Sharma-Kuinkel BK, Marco F, Wray D, Kanafani ZA, Carugati M, Durante-Mangoni E, Tattevin P, Chu VH, Moreno A, research grants Fowler VG Jr, Miró JM; International Collaboration on Endocarditis Microbiology Investi- gators. Clin Microbiol Infect. 2017;23(8):544-549. Doi: 10.1016/j.cmi.2017.01.017 Transmission between archaic and modern human ancestors during the evolution of the oncogenic human papillomavirus 16. High level methicillin resistance correlates with reduced Staphylo- Pimenoff VN, Mendes de Oliveira C, Bravo IG. Mol Biol Evol. 2017;34(1):4-19. doi: coccus aureus endothelial cell damage. 10.1093/molbev/msw214 Seidl K, Leemann M, Palheiros Marques M, Rachmühl C, Leimer N, Andreoni F, Ach- ermann Y, Zinkernagel AS. Int J Med Microbiol. 2017;307(1):11-20. doi: 10.1016/j. Right to vote Squamous intraepithelial lesions of the anal squamocolumnar ijmm.2016.11.009 and participate junction: Histopathological classification and HPV genotyping. Clavero O, McCloskey J, Molina VM, Quirós B, Bravo IG, de Sanjosé S, Bosch FX, The transcriptome of Mycobacterium tuberculosis in a lipid-rich in ESCMID Pimenoff VN. Papillomavirus research. 2017;3:11-17. Doi: 10.1016/j.pvr.2016.12.001 dormancy model through RNAseq analysis. Aguilar-Ayala DA, Tillema L, Van Nieuwerburgh F, Deforce D, Palomino JC, Vandamme Endoplasmic reticulum chaperone Gp96 controls actomyosin P, Gonzalez-Y-Merchand JA, Martin A, Sci. Rep. 2017;7:17665. doi:10.1038/s41598-017- dynamics and protects against pore-forming toxins. 17751-x Mesquita FS, Brito C, Mazon Moya MJ, Pinheiro JC, Mostowy S, Cabanes D, Sousa S. Participation in EMBO Rep. 2017;18(2):303-318. doi: 10.15252/embr.201642833 Distribution of putative virulence markers in Enterococcus faecium: towards a safety profile review. study groups Nebulization of Antiinfective Agents in Invasively Mechanically Freitas AR, Tedim AP, Novais C, Coque TM, Peixe L. Journal of Antimicrobial Chemother- Ventilated Adults: A Systematic Review and Meta-analysis. apy. 2017;73(2):306-319. doi: 10.1093/jac/dkx387. Solé-Lleonart C, Rouby JJ, Blot S, Poulakou G, Chastre J, Palmer LB, Bassetti M, Luyt CE, Pereira JM, Riera J, Felton T, Dhanani J, Welte T, Garcia-Alamino JM, Roberts JA, Rello J. Anti-biofilm Properties of Bacterial Di-Rhamnolipids and Their Semi- Anesthesiology. 2017;126(5):890-908. doi: 10.1097/ALN.0000000000001570 Synthetic Amide Derivatives. Become an Aleksic I, Petkovic M, Jovanovic M, Milivojevic D, Vasiljevic B, Nikodinovic-Runic J, Sen- Genetic diversity of Plasmodium vivax metacaspase 1 and Plas- erovic L. Front Microbiol. 2017;8:2454. doi: 10.3389/fmicb.2017.02454. modium vivax multi-drug resistance 1 genes of field isolates from ESCMID member Mauritania, Sudan and Oman. KKL-35 exhibits potent antibiotic activity against Legionella species Sow F, Bonnot G, Ahmed BR, Diagana SM, Kebe H, Koita M, Samba BM, Al-Mukhaini SK, independently of trans-translation inhibition. Al-Zadjali M, Al-Abri SS, Ali OA, Samy AM, Hamid MM, Ali Albsheer MM, Simon B, Bienv- Brunel R, Descours G, Durieux I, Doublet P, Jarraud S, Charpentier X. Antimicrob Agents enu AL, Petersen E, Picot S. Malar J. 2017;16(1):61. doi: 10.1186/s12936-017-1687-1 Chemother. 2017 Nov 20. pii: AAC.01459-17. doi: 10.1128/AAC.01459-17. [Epub ahead Registration of print] and sign up Polymicrobial Ventilator-Associated Pneumonia: Fighting In Vitro discounts for Candida albicans-Pseudomonas aeruginosa Biofilms with Anti- The contribution of Pseudomonas aeruginosa virulence factors and fungal-Antibacterial Combination Therapy. host factors in the establishment of urinary tract infections. events Rodrigues ME, Lopes SP, Pereira CR, Azevedo NF, Lourenço A, Henriques M, Pereira MO. Newman JW, Floyd RV, Fothergill JL. FEMS Microbiol Lett. 2017;364(15). doi: 10.1093/ for study groups PLoS One. 2017;12(1):e0170433. doi: 10.1371/journal.pone.0170433. femsle/fnx124.

Genetic diversity, transmission dynamics and drug resistance of Structural similarities in the CPC clip motif explain peptide-binding Mycobacterium tuberculosis in Angola. promiscuity between glycosaminoglycans and lipopolysaccharides. www.escmid.org/membership Perdigão J, Clemente S, Ramos J, Masakidi P, Machado D, Silva C, Couto I, Viveiros M, Pulido D,Rebollido-Rios R, Valle J, Andreu D, Boix E, Torrent M. J R Soc Interface. [email protected] Taveira N, Portugal I. Sci Rep. 2017;7:42814. doi: 10.1038/srep42814. 2017;14(136). pii: 20170423. doi: 10.1098/rsif.2017.0423.

Long-Chain 4-Aminoquinolines as Quorum Sensing Inhibitors in Centrality in the host–pathogen interactome is associated with VISIT US! Serratia marcescens and Pseudomonas aeruginosa. pathogen ﬁtness during infection. IN THE ESCMID WORLD Aleksic´ I, Šegan S, Andric´ F, Zlatovic´ M, Moric I, Opsenica DM, Senerovic L. ACS Chem Asensio NC, Giner EM, De Groot NS, Burgas MT. Nature Commun. 2017;8:14092. doi: AT ECCMID MADRID, HALL 9 Biol. 2017;12(5):1425-1434. doi: 10.1021/acschembio.6b01149. 10.1038/ncomms14092

38 YEARBOOK 2017/2018 PUBLICATIONS YEARBOOK 2017/2018 PUBLICATIONS 39

RZ_Membership_A4_2018.02.05.indd 1 05.02.18 11:24 ESCMID Educational Activities

“We believe that appropriate education of young members is essential to improving the quality of patient care.”

Evelina Tacconelli ESCMID Education Ofﬁcer [email protected]

The 2017 education programme again had many highlights and of- tical applicability. It was the pilot event for the EUCIC European 1 – 8 July 2017. The event covered a broad range of topics in mitted by the end of May 2018, so we can meet our mid-July dead- fered participants high-quality courses in the field of infectious dis- Infection Control Certification, which started in 2018. Participants CM and ID and attracted a record-breaking number of 80 partici- line for the full programme. Individual members are welcome to eases, clinical microbiology and infection control. ESCMID is very were able to learn how to identify their own real-life healthcare pants (78 last year in Seville) from 26 countries all over the world! contact us with their own ideas for future courses and workshops proud of having delivered 17 courses involving experts from multi- network and how to implement a regional network focusing on in- As usual the Summer School programme included lectures by and, of course, we highly recommend taking part in this year’s pro- ple countries and backgrounds. We would like to thank the ESCMID fection and resistance prevention, including all major healthcare international experts on diverse and highly interesting topics in gramme. Study Groups and ESCMID members who contributed to the great facilities. infectious diseases and clinical microbiology, workshops and stu- I would like to end by thanking all members of the Education programme we were able to offer our members in 2017! Following ESCMID also offered a course on migration health, one of dent presentations, all in a relaxed atmosphere. The participants Subcommittee for their work and help in building the ESCMID edu- suggestions and requests from students in previous courses, the the hottest topics in recent years. The event was organized by not only had the opportunity to attend the state-of-the-art lectures cation programme. ratio of technical workshops to postgraduate courses has shifted ESGITM, UNESCO Chair for “training and empowering human re- by experts in these fields and network with renowned specialists, towards the latter (4 technical workshops and 13 postgraduate sources for health development in resource-limited countries”, but also enjoyed the sightseeing activities in the idyllic surround- courses). The number of participants varied depending on the type International Organization for Migration (IOM), International Soci- ings in northern Germany. and format of the course. Most of the educational courses attract- ety of Travel Medicine (ISTM), Italian Society of Migration Medicine Education subcommittee ed between 30 and 70 participants, whereas the attendance num- (SIMM), University of Palermo, Italian Society of Infectious and ESCMID supports young scientist members Evelina Tacconelli, Tübingen, Germany, Chair bers for technical workshops were deliberately kept a little smaller Tropical Diseases (SIMIT) and Italian Society of Tropical Medicine We believe that appropriate education of young members is es- Esmita Charani, London, United Kingdom to guarantee close interaction during the practical sessions. and Global Health (SIMET). The course participants gained detailed sential to improving the quality of patient care and reduce medical Cansu Çimen, Istanbul, Turkey More than 700 delegates from over 65 countries attended our insight into the various multi-faceted aspects of migration health, errors. ESCMID’s educational events implement a translational and educational courses in 2017. The events were rated 3,50/4,00 on including migration-related infections and ethics of migration multi-faceted approach to education. This year ESCMID once again Giovanni Delogu, Rome, Italy average, confirming the high-quality educational content of ESCMID health. provided numerous grants for junior colleagues to attend courses Önder Ergönül, Istanbul, Turkey educational events. The other courses, all very successful, were hosted in different and workshops. We are aware that they often experience economic Laurent Poirel, Fribourg, Switzerland For the very first time, a course was held in the city of ESCMID’s cities located all over Europe, including Amsterdam (Sepsis 2017: difficulties and for this reason ESCMID is glad to provide funding Kaisu Hellevi Rantakokko-Jalava, Turku, Finland headquarters in Basel. As many as 55 delegates from 20 countries from pathogenesis to treatment – EPASG, ESGBIS, ESGCIP), Pam- for its educational events. The education programme provides ex- Katja Seme, Ljubljana, Slovenia attended this highly rated event mid-March, which tackled a new plona (update on infections associated with orthopaedic implants: cellent opportunities for young members to extend their training Agnes Maria Sonnevend, Al Ain, United Arab Emirates topic, applications of MALDI-TOF Mass-Spectrometry. diagnosis and management – ESGIAI), Bratislava (viral infections and interact with international experts. While attending courses The course on the diagnosis of bloodstream infections held in in immunocompromised patients – ESGICH, ESGVH), La Tronche and workshops in person is the most beneficial, all members have Maria Souli, Athens, Greece Nice was a great example of the successful collaboration among (omics of host and pathogens during infections – ESGIB, ESGMD), access to the ESCMID eLibrary, which includes presentations of all Thea-Christin Zapf, Marburg, Germany several ESCMID Study Groups. Co-organized in a joint effort by ES- Turin (management of infections in septic shock patients – ESGCIP), educational activities and is available at www.escmid.org/elibrary. Snježana Židovec Lepej, Zagreb, Croatia GBIS, EFISG, ESGB, ESGEM, ESGMD, ESGS and the University of Nice- Fribourg (emerging antibiotic resistance in Gram-negative bacte- Sofia Antipolis/Université Côte d’Azur, the course proved to be one ria: problems and solutions – ESGARS), Istanbul (antimicrobial EUCIC Certification in Infection Control of the best rated events in ESCMID’s history (3,73/4,00). Congrat- stewardship: principles and practice – ESGAP), Freiburg (capacity- This started in March 2018! For full details see page 26. ulations to all who made it so successful! building workshop: whole-genome sequencing for clinical micro- ESCMID’s educational activities are also integrated in many biology and hospital epidemiology – ESGEM, ESGMD) and Madrid Outlook for 2018 European funded projects. One successful example this year was (antibiotic therapy in practice – ESGAP, TAE). Once again the education programme looks very exciting. Have a the course on (re-)emerging arbovirus infections in Europe held in Following a long-standing tradition, ESCMID hosted several look at the calendar section on the society’s website for full details Zagreb. The course is an integral part of PREPARE, an EU-funded courses outside Europe, namely in Muscat, Oman (hospital-ac- of the 2018 education programme (www.escmid.org/calendar). partnership aimed at strengthening European preparedness for quired infections), Taipei, Taiwan (antimicrobial resistance across The e-learning pilot projects were defined and study group (re-)emerging infectious disease outbreaks. This course was held Europe and the Far East) and Herzliya, Israel (integration of next- members are currently finalizing the activities in collaboration for the second time (2016 in Thessaloniki), and the general per- generation sequencing in the clinical microlab). All courses were with external experts. We are looking forward to launching the first ception was very good (rating of 3,74/4,00). ESCMID is very proud very successful in terms of attendance and perception, and ESCMID activities, probably around this year’s ECCMID. to be part of this valuable initiative. will try to further extend its commitment on other continents in the I am very pleased to announce that the next Summer School The course on infection and resistance prevention in the re- future! will be held in Paris, France, 1 – 7 July 2018. Registration is open gional healthcare network held in Groningen and co-organized by and details can be found online at www.escmid.org/education. EUCIC, ESGEM and the University Medical Center Groningen, was 16th ESCMID Summer School – another record-breaking highlight! We have already contacted all the study groups and affiliated deemed very valuable by participants in terms of theory and prac- The 16th Summer School took place in Borstel, Germany, from societies to ask for their ideas for the 2019 programme to be sub-

40 YEARBOOK 2017/2018 EDUCATION YEARBOOK 2017/2018 EDUCATION 41 3rd course on principles of molecular microbiological diagnostics ESCMID Courses and Workshops ESCMID Postgraduate Education Course 17 – 19 January 2018, Maastricht, Netherlands Organized by the ESCMID study group for epidemiological markers (ESGEM), ESCMID study group for genomic and molecular diagnostics (ESGMD), Maastricht University Medical Centre

Workshop on migrant health Antimicrobial resistance across Europe and the Far East: Emerging antibiotic resistance in Gram-negative bacteria: ESCMID Postgraduate Education Course target audience issues and solutions problems and solutions 8 – 10 March 2018, Muscat, Oman ESCMID Postgraduate Education Course ESCMID Postgraduate Technical Workshop Organized by the ESCMID study group for clinical parasitology 27 – 28 May 2017, Taipei, Taiwan 14 – 15 September 2017, Fribourg, Switzerland (ESGCP), ESCMID study group for epidemiological markers Organized by the ESCMID fungal infection study group (EFISG), Organized by the ESCMID study group for antimicrobial resistance (ESGEM), ESCMID study group for infections in travellers and ESCMID study group for antimicrobial resistance surveillance surveillance (ESGARS), University of Fribourg migrants (ESGITM), ESCMID study group for mycobacterial Maastricht, Netherlands 2018 (ESGARS), ESCMID International Affairs Subcommittee, infections (ESGMYC), ESCMID study group for viral hepatitis Global Chinese Association for Clinical Microbiology and Infectious Migration health (ESGVH), the European Centre for Disease Prevention and Control Diseases (GCACMID) ESCMID Postgraduate Education Course (ECDC), WHO EMRO, ESCMID Task Force for Emerging Infections, 1 – 4 October 2017, Palermo, Italy Ministry of Health, Muscat, Oman Advanced technical workshop: infection and resistance Organized by the ESCMID study group for infections in travellers prevention in the regional healthcare network and migrants (ESGITM), UNESCO Chair “training and empowering Adult immunization: new and old challenges ESCMID Postgraduate Technical Workshop human resources for health development in resource-limited ESCMID Postgraduate Education Course 1 – 2 June 2017, Groningen, Netherlands countries”, University of Brescia, Italy, International Organization 16 – 17 March 2018, São Paulo, Brazil Organized by the ESCMID study group for epidemiological for Migration (IOM) – the UN Migration Agency, International Organized by the ESCMID vaccine study group (EVASG), markers (ESGEM), European Committee on Infection Control Society of Travel Medicine (ISTM), Italian Society of Migration Brazilian Society of Infectious Diseases (SBI), Brazilian (EUCIC), University Medical Center Groningen Medicine (SIMM), University of Palermo, Italian Society of Immunization Society (SBIM) Infectious and Tropical Diseases (SIMIT), Italian Society of Tropical Sepsis 2017: from pathogenesis to treatment Medicine and Global Health (SIMET) Update on endocarditis and endovascular infections ESCMID Postgraduate Education Course ESCMID Postgraduate Education Course 1 – 3 June 2017, Amsterdam, Netherlands Antimicrobial stewardship: principles and practice 20 – 23 March 2018, Münster, Germany Organized by the ESCMID PK/PD of anti-infectives study group ESCMID Postgraduate Education Course Organized by the ESCMID study group for bloodstream infections Freiburg, Germany 2017 (EPASG), ESCMID study group for bloodstream infections 5 – 6 October 2017, Istanbul (Kadıköy), Turkey and sepsis (ESGBIS), ESCMID study group for implant-associated and sepsis (ESGBIS), ESCMID study group for infections in Organized by the ESCMID study group for antibiotic policies infections (ESGIAI), ESCMID study group for staphylococci critically ill patients (ESGCIP), European Sepsis Academy (ESGAP), Turkish Society of Clinical Microbiology and Infectious and staphylococcal diseases (ESGS), University Clinics Münster, Diseases (KLIMIK) Institute of Medical Microbiology Update on infections associated with orthopaedic implants: diagnosis and management Capacity-building workshop: whole-genome sequencing for Preparing for (re-)emerging arbovirus infections in Europe ESCMID Postgraduate Education Course clinical microbiology and hospital epidemiology ESCMID Postgraduate Education Course 7 – 9 June 2017, Pamplona, Spain ESCMID Postgraduate Technical Workshop 21 – 23 March 2018, Bucharest, Romania Organized by the ESCMID study group for implant-associated 10 – 13 October 2017, Freiburg, Germany Organized by the ESCMID study group for infections in travellers infections (ESGIAI), Clínica Universidad de Navarra, Organized by the ESCMID study group for epidemiological markers and migrants (ESGITM), Erasmus MC: University Medical Spanish nosocomial infection study group (GEIH), Spanish (ESGEM), ESCMID study group for genomic and molecular Center Rotterdam, University of Oxford Society for Clinical Microbiology and Infectious Diseases (SEIMC) diagnostics (ESGMD), University of Freiburg Medical Center, University Medical Center Groningen (UMCG) Challenges in veterinary hospital infection control and Viral infections in immunocompromised patients antimicrobial stewardship ESCMID Postgraduate Education Course Regional capacity-building for integration of next-generation ESCMID Postgraduate Education Course 8 – 9 June 2017, Bratislava, Slovakia sequencing in the clinical microlab 4 April 2018, Birmingham, United Kingdom Istanbul, Turkey 2017 Organized by the ESCMID study group for infections in compromised ESCMID Postgraduate Education Course Organized by the ESCMID study group for antimicrobial hosts (ESGICH), ESCMID study group for viral hepatitis (ESGVH) 30 October – 1 November 2017, Herzliya, Israel stewardship (ESGAP), ESCMID study group for veterinary micro- Organized by the ESCMID study group for genomic and molecular biology (ESGVM) Omics of host and pathogens during infections diagnostics (ESGMD), ESCMID study group for epidemiological ESCMID Postgraduate Education Course markers (ESGEM), ESCMID study group for forensic and Antimicrobial stewardship: implementing the change 6 – 8 September 2017, La Tronche, France post-mortem microbiology (ESGFOR), ESCMID study group ESCMID Postgraduate Education Course Organized by the ESCMID study group for infectious diseases of for legionella infections (ESGLI), Israeli Society for Infectious 19 – 20 April 2018, San Lorenzo de El Escorial, Spain the brain (ESGIB), ESCMID study group for genomic and molecular Diseases (ISID) Organized by the ESCMID study group for antimicrobial steward- diagnostics (ESGMD), Medical University of Grenoble ship (ESGAP), GEIRAS, study group on healthcare-associated Antibiotic therapy in practice infections of the Spanish Society of Infectious Diseases and Management of infections in septic shock patients ESCMID Postgraduate Technical Workshop Clinical Microbiology (SEIMC), Madrid, Spain ESCMID Postgraduate Education Course 2 – 4 November 2017, Madrid, Spain 7 – 8 September 2017, Turin, Italy Organized by the ESCMID study group for antibiotic policies Organized by the ESCMID study group for infections in critically (ESGAP), Hospital Universitario Ramón y Cajal, Madrid, Spain, ill patients (ESGCIP), Department of Medical Sciences, University Medical Center Utrecht, Trainee Association of University of Turin ESCMID (TAE) Herzliya, Israel 2017

42 YEARBOOK 2017/2018 EDUCATION YEARBOOK 2017/2018 EDUCATION 43 16th ESCMID Summer School Borstel, Germany, 1 – 8 July 2017

Christoph Lange, Bernd Salzberger and Laurent Poirel 16th ESCMID Summer School Directors

A week of inspiration and team building. The 16th ESCMID Summer mer School took on the role of teachers and were encouraged to School took place at the beautiful Borstel Research Center in ru- present a clinical case or research project in which they had been ral northern Germany. The 80 participants came from 26 different involved. Those presentations offered the opportunity for lively countries and stayed on the former farm estate, today one of the discussions and provided feedback from peers and experts in the prestigious Leibniz Institutes and the National Reference Center field. The level of presentations, the quality of comments and the for Mycobacteria in Germany. ESCMID financially supported 20 of atmosphere of respect and learning together was outstanding. the delegates so they could attend the Summer School. The Ger- The programme was rounded off by visits to the harbour in 17th ESCMID man Center for Infection Research (DZIF) provided 13 additional Hamburg, the medieval city centre of Lübeck and its Hansemuse- scholarships. Each year the ESCMID Summer School is one of the um, a Wild West open-air theatrical performance at the Karl-May finest events for young clinicians and scientists working in the festival in Bad Segeberg and with BBQ and sports in the Borstel gar- Summer School field of clinical microbiology and infectious diseases. With 42 in- dens behind the Manor House. ternational members of the ESCMID faculty, we reached the highest In 2018 we move from the countryside to one of the most Paris, France number of teaching staff at a Summer School so far. beautiful cities in the world: from 1 – 7 July 2018 the 17th ESCMID Christoph Lange (Borstel), Bernd Salzberger (Regensburg) Summer School will take place in Paris, France. Watch out for the and Laurent Poirel (Fribourg) co-directed this Summer School with interesting programme and apply in time! The ESCMID Summer 1 – 7 July 2018 the help of the ESCMID Education Subcommittee. ESCMID’s Presi- School offers the best opportunity to remain up-to-date in your dent Mario Poljak was active at the Summer School throughout the field and to get to know your peers. week. The scientific programme covered all important aspects of clinical microbiology and infectious diseases, from bench to bed- side, including hot topics. Highlights were parallel small group tutorials on modern tools for bacterial identification and antibiotic susceptibility testing, radiology for infectious diseases special- A one-week course dedicated to postgraduate and ists, hands-on visits to the mycobacteriology lab and interactive ID continuing medical education. The programme covers teaching ward rounds at Borstel’s internationally renowned medi- a broad range of topics in clinical microbiology and cal clinic. As in previous years, participants at the ESCMID Sum- infectious diseases and will interest young MDs at the end of their specialty training as well as biologists, pharmacists, PhD students and postdoctoral fellows working in the infection field.

Please register at www.escmid.org/education. Places are limited, apply until 1 June 2018!

Organized by the ESCMID Education Subcommittee Hosted at FIAP, 30 rue Cabanis, 75014 Paris, France Summer School www.escmid.org/education

44 YEARBOOK 2017/2018 ADVERTS YEARBOOK 2017/2018 EDUCATION 45

RZ_Ins_SummerSchool2018.indd 1 08.02.18 15:04 4th ESCMID Conference on Vaccines Dubrovnik, Croatia, 8 – 10 September 2017

The 4th ESCMID Conference on Vaccines, which was devoted to the cies associated with diarrhoea. Co-administered with a rotavirus Hot topics topic New and old diseases in children and adults – unmet needs, vaccine, hospitalizations and primary care consultations of chil- Robb Butler from WHO addressed inequity in vaccine opportunities took place in Dubrovnik, Croatia, from 8 – 10 September 2017. More dren below the age of five would decline by half. Experimental in Europe and discussed the hot topic of how experts can approach than 100 participants attended the conference where over 30 in- norovirus vaccines are currently in the final stages of clinical de- the media and the public to convince them that vaccines are safe ternationally renowned experts presented and debated the most velopment before they can be marketed. The target groups should and effective. International leader Louis Bont from the Netherlands recent data and approaches that will protect generations to come be travellers, the military, elderly people in care facilities and im- chaired a symposium reviewing new vaccines targeting respira- from vaccine-preventable diseases. munocompromised patients. Children would particularly benefit tory syncytial virus (RSV), which causes a great disease burden from the combination with a rotavirus vaccine. in children and adults. The conference also covered new and im- Scientific programme proved vaccines and approaches for diseases that are traditionally Novel inventions, better understanding of disease pathogenesis, Polio eradication prevented by vaccination, such as pneumococcal diseases, tuber- and improved surveillance are constantly redefining vaccine strat- Other highlights included a presentation by Ananda Bandyopad- culosis, diphtheria and meningococcal infections. egies. The European section of the World Health Organization (WHO) hyay from the Bill & Melinda Gates Foundation, who showed that and the European Centre for Disease Prevention and Control (ECDC) we are closer than ever to reaching the goal of the Global Polio Organizing committee helped develop a scientific programme that addressed the most Eradication Initiative, which the foundation actively supports. This conference was organized with the help of the ESCMID Vaccine pressing questions. The most important topics were equity in im- The main strategies are the interruption of transmission through Study Group (EVASG) with the support and active participation of munization, exposing the gaps in vaccine-preventable diseases, Robb Butler, Ron Dagan chairing a session intense vaccination efforts and preparedness for vaccine policy the ECDC and WHO Europe. Ron Dagan, an international figure in vaccines for new global threats, innovative approaches for vaccines changes. This requires adequate supply and optimum utilization paediatric vaccines from Israel, chaired the organizing commit- against old diseases, approaches and communication for the imple- of routine immunization and mass campaigns, innovation around tee, which also includes Robb Butler from WHO Europe in Denmark; mentation of vaccines, and non-specific effects of vaccines. High- newer formulations and delivery technologies, and risk mitigation ESCMID President Mario Poljak from Slovenia; EVASG study group lights included presentations on the progress that has been made and containment measures. This effort will allow historic progress chair Susanna Esposito from Italy; and Lucia Pastore Celentano in the management of viral diseases, including the Zika and Ebola to be made and sustainably eradicate the disease from the globe. from ECDC in Sweden. viruses, which have caused recent difficult-to-contain outbreaks. Non-specific vaccine effects Zika management Federico Martinon-Torres from Spain addressed unexpected, non- Marco Aurelio Safadi from São Paulo reviewed the tragedy of con- specific benefits vaccines may have or develop. He discussed the genital Zika syndrome in Brazil, showing that the only interven- heterologous vaccine effects of products against Bacilli Calmette- tion currently available to decrease the burden of Zika and other Guerin (BCG), measles, polio, diphtheria-tetanus-pertussis (DTP) arboviruses is mosquito control. So far this has been unsuccessful and rotavirus. He showed that unknown direct and indirect effects for Aedes spp mosquitoes in his setting. He observed that the co- of vaccines may result in true heterologous effects. BCG vaccina- circulation of dengue, Zika and chikungunya occurred for the first tion at birth in well developed countries may for example decrease time in Brazil, where the potential teratogenicity of Zika was also hospitalizations in children due to respiratory viral infections and established for the very first time. He stated that the true burden of sepsis not related to tuberculosis, or the administration of measles the congenital disease associated with Zika is probably underesti- Robb Butler, Ron Dagan, Susanna Esposito, Mario Poljak vaccine may prevent opportunistic secondary infection through mated and that there are still unanswered questions regarding the (members of the organizing committee) heterologous protection. role of co-infections, previous infections and other risk factors in the neurological outcomes and for congenital disease.

New vaccines Top experts discussed the current status of some new vaccines of cine that would offer protective efficacy of at least 75 percent. the utmost importance. One of the highlights was the presentation Another goal for the vaccine would be to reduce transmission of by vaccinology legend Stanley Plotkin on the challenges faced in the parasite and thereby substantially reduce the incidence of hu- the development of a human cytomegalovirus (CMV) vaccine. He man malaria infection. He outlined that there has been consider- pointed out that although many lessons have been learned from able progress. The anti-sporozoite vaccine RTS,S/AS01 is leading prior trials there are still unanswered questions regarding the cel- the way, although it may not reach the market before 2023, while lular immune response in maternal-foetal transmission. Research experimental candidate R21 with adjuvant vaccine candidate ma- needs to be conducted to assess whether maternal-foetal infection trix-M could be licensed by then as well. Components focusing on in seropositive women can be prevented by boosting antibody or vectored liver-stage, conserved blood-stage antigen, and mosqui- cell-mediated immunity and whether protective immune respons- to-stage should increase the efficacy of potential vaccines, he ex- es can be prolonged beyond child-bearing age. Still, he stressed plained. that there is ample need for a CMV vaccine. There is already proof Miguel O’Ryan from Chile discussed the need for vaccines of concept for a CMV vaccine and there are many candidate vac- to fight noroviruses, the most common cause of gastroenteritis, cines currently in development. which strikes almost 700 million times every year. He stressed Adrian Hill from the Jenner Institute in Oxford reviewed the that a vaccine would reduce the number of primary care visits, challenges and progress in the development of a malaria vac- emergency room visits as well as hospitalizations and emergen-

46 YEARBOOK 2017/2018 CONFERENCES YEARBOOK 2017/2018 CONFERENCES 47 27th ECCMID from 22 – 25 April 2017 60 in Vienna, Austria 50 40 Figure 3. Country of origin 30 of Speakers and Chairs 53 Countries “ECCMID is developing into one of the most important 20 569 Speakers and chairs

infectious diseases meetings in the world, bringing 10

together modern diagnostics, medical microbiology, 0 Italy Peru clinical infectious diseases, public health and India Israel China Spain Brazil Egypt Japan Turkey Poland France Mexico Greece Austria Ireland Croatia Tunisia Cyprus Canada Finland Estonia Norway Belarus Sweden Bulgaria Belgium Vietnam Portugal Slovenia Thailand Hungary Lebanon Australia Romania Germany Colombia Denmark Argentina Costa Rica Azerbaijan infection control specialists from different settings to Hong Kong Switzerland South Africa Netherlands United States Czech Republic United Kingdom United

tackle today’s communicable health challenges.” Polynesia French Russian Federation Saint Kitts and Nevis and Kitts Saint

Winfried V. Kern China of Republic Taiwan, ECCMID Programme Director Bolivia of Republic Venezuela, [email protected]

The 27th edition of the European Congress of Clinical Microbiology 13,000 20 educational workshops and 20 meet-the-expert sessions. It 4% 2% and Infectious Diseases (ECCMID) was held in Vienna, Austria, from 12,000 also offered attendees 26 industry-organized symposia and an 6% 22 – 25 April 2017. ECCMID is today the largest infectious disease Figure 1. exhibition with 194 exhibitors. As many as 381 speakers and meeting in the world, bringing together clinicians, scientists, public 11,000 Number of attendees 188 chairs participated in the congress and about 32% of this total 10% health experts and delegates from diagnostic and drug companies 10,000 of 569 were women. as well as other experts in infection and microbiology from around 9,000 the globe. Abstracts 8,000 Of the 5,223 regular and late-breaking abstracts received from 10% Attendees 106 different countries, 3,393 abstracts were presented in oral, 7,000 67% As many as 12,494 people from 126 countries attended ECCMID, ePoster and paper poster sessions. A record number of 33 late- with the top 10 countries of provenance being the United Kingdom, 6,000 breaking abstracts with exciting recent fi ndings were presented the United States of America, Germany, France, Italy, Spain, Austria, 5,000 in three dedicated oral sessions on clinical trials, diagnostics, and Switzerland, the Netherlands and Belgium. More than 70 journal- vaccines, attracting many interested delegates. ists were registered for the congress. 4,000 3,000 Highlights Scientifi c programme The highlights of ECCMID 2017 included the keynote speech by Figure 4. Geographical 2,000 The congress featured more than 200 sessions covering the en- Thierry Calandra, winner of the ESCMID Excellence Award for his analysis of participants tire fi eld of infectious diseases and clinical microbiology, including 1,000 outstanding lifetime achievements in the fi eld of sepsis. Key topics Europe Asia 12 keynote lectures, more than 100 symposia and oral sessions, 0 at last year’s congress were antimicrobial resistance with a focus North America on susceptibility testing, antimicrobial stewardship and infection Middle East & North Africa 2017 2013 2014 2015 2016 control and prevention. They were presented as keynote sessions, South & Central America original research papers and in workshops. The congress also ex- Australia & New Zealand Africa tensively covered different aspects of the big four in infectious 10,000 diseases: HIV, viral hepatitis, tuberculosis and malaria. Nobel prize 9,000 winner Françoise Barré-Sinoussi held a keynote about the HIV epi-

8,000 demic, Sir Nicholas White talked about the elimination of malaria and Wenhui Li discussed his discovery of the hepatitis B virus re- 7,000 ceptor, while tuberculosis was covered in more than 100 presenta- 6,000 tions. We had crowd-drawing sessions on emerging infections and novel diagnostic techniques as well as the role of microbiota during 5,000 the keynote by Eric G. Pamer, just to name a few. 4,000

3,000 Figure 2. Number of abstracts submitted 2,000

1,000

0 2012 2010 2011 1991 1997 1987 1983 1993 1989 2001 1995 2007 1999 2013 2002 2003 2009 2005 2004 2000 2006 2008 2017 2014 2015 2016

48 YEARBOOK 2017/2018 ECCMID YEARBOOK 2017/2018 ECCMID 49 Outlook I want to take this opportunity to thank everyone who made ECCMID 28th ECCMID from 21 – 24 April 2018 2017 such a success. My thanks in particular go to my friends and colleagues on the programme committee, who spent considerable in Madrid, Spain time and effort to develop such an attractive programme, to all the dedicated reviewers, who helped assess the submitted abstracts, and to the people in the ESCMID Executive Ofﬁce, whom I kept busy all the time and who organized the meeting in a highly professional manner. Looking back at the record-breaking congress we Winfried V. Kern achieved in Vienna, I have a good feeling about what we can do in ECCMID Programme Director Madrid in 2018. Hasta luego! [email protected]

It is my pleasure and a great privilege to welcome you to the learn about recent findings in therapeutic approaches and strate- Attendance 28th European Congress of Clinical Microbiology and Infectious gies in the battle against infectious diseases. Attendees 12,494 Diseases in Madrid. As the organizers of the leading congress com- The ECCMID programme committee has once again prepared Top 10 attendee countries bining clinical microbiology and infectious diseases, we strive to an accompanying series of classical oral sessions and poster pres- (from 126 countries) 1. United Kingdom 6. Spain continually increase the scientific excellence of our annual meet- entations, representing a superb cross section from among the 2. USA 7. Austria ing. To achieve this goal, the ECCMID programme committee has best-rated submitted abstracts. Participants will have the opportu- 3. Germany 8. Switzerland selected the very best proposals for invited symposia, educational nity to meet researchers from many parts of the world to discuss 4. France 9. Netherlands workshops and meet-the-expert sessions, and I am sure you will methods, results and the impact on clinical and laboratory prac- 5. Italy 10. Belgium be excited by this year’s timely and top-quality keynote presenta- tice. Interactive sessions will allow participants to get involved and Faculty tions by speakers from all over the world. Leaders and specialists obtain the maximum benefit from the sessions. Scientists, includ- Speakers & chairs 569 from all disciplines in the fields of microbiology and infectious dis- ing clinicians, and public health specialists will present findings, Male 258 (68%) Female 123 (32%) eases will be discussing the latest developments and hot topics. recommendations and award-winning research projects and will Again we expect more than 12,000 participants who are keen to respond to the most pressing scientific questions on diagnosis, Scientific programme Abstracts submitted 5,223 prevention, clinical care and management of infection. Abstracts accepted 3,393 As in previous years, young professionals will have the oppor- Sessions tunity to discuss their ideas and projects with renowned experts Educational workshops 20 in meet-the-expert sessions and during round table discussions. TAE Trainees Day 1 ECCMID 2018 Programme Committee Mario Poljak, Ljubljana, Slovenia The most popular sessions include keynote lectures, presentations Meet-the-expert 20 Murat Akova, Ankara, Turkey Elisabeth Puchhammer, Vienna, Austria from Young Investigator Awardees, Clinical Grand Rounds as well as Keynote 12 our famous “Year in ...” sessions. The keynote speeches will include Symposia (2 hours) 40 Sevtap Arikan-Akdagli, Ankara, Turkey Camilla Rodrigues, Mumbai, India Symposia (1 hour) 20 presentations on what viruses can teach us about immunology, Robert Bonomo, Cleveland, OH, United States Jesús Rodriguez-Baño, Seville, Spain ePoster orals 36 the Spanish influenza, global action against antimicrobial resist- Oral session 55 Thierry Calandra, Lausanne, Switzerland Holger Rohde, Hamburg, Germany ance, the microbiome, the management of resistant bacteria and Integrated Symposia 26 Jordi Carratala, Barcelona, Spain Maurizio Sanguinetti, Rome, Italy one of the big four infectious diseases: tuberculosis. Poster sessions 101 Francesco Castelli, Brescia, Italy Katja Seme, Ljubljana, Slovenia A variety of topics have been accepted for this year’s late- Sponsorship & Exhibition breaking abstracts and we particularly want to provide a stage for Sponsors 24 Jon Friedland, London, United Kingdom Mark Shirtliff, Baltimore, MD, United States the most recent findings on vaccine-preventable diseases and from Exhibition Sq. M 5,261.5 Alexander Friedrich, Groningen, Netherlands Maria Souli, Athens, Greece Exhibitors 194 recently completed clinical trials. For the third time, ECCMID will fea- Ana Gales, São Paulo, Brazil Arnfinn Sundsfjord, Tromsö, Norway Press ture a pipeline corner where innovative companies and research Registered journalists 70 Carolina Garcia Vidal, Barcelona, Spain Yupin Suputtamonkol, Bangkok, Thailand groups will be offered a platform to present their early-stage anti- Press releases 6 Christian Giske, Stockholm, Sweden Evelina Tacconelli, Tübingen, Germany microbial therapies, their diagnostic products in development and Mary Horgan, Cork, Ireland Arjana Tambic´ Andraševic´, Zagreb, Croatia research opportunities to a wider audience. The ECCMID workshops, Table 1. Key ECCMID figures organized by ESCMID’s study groups and the Trainee Association of Po-Ren Hsueh, Taipei, Taiwan Kate Templeton, Edinburgh, United Kingdom ESCMID (TAE) and ESCMID partner groups and organizations will Winfried Kern, Freiburg, Germany Jean-François Timsit, Paris, France offer superb networking opportunities. Visit our new partner vil- Jan Kluytmans, Breda, Netherlands Françoise van Bambeke, Brussels, Belgium lage in the ESCMID World and listen to the talks and debates about Dimitrios Kontoyiannis, Houston, TX, United States Linos Vandekerckhove, Ghent, Belgium research funding opportunities, health policy issues and new per- Jaime Labarca, Santiago, Chile Annelies Zinkernagel, Zurich, Switzerland spectives in various fields of infectious diseases. Frédéric Laurent, Lyon, France We hope that after a day full of inspiring sessions and fruitful discussions you will have time to explore Madrid, a cosmopolitan Amel Letaief, Sousse, Tunisia city with a rich history in art, architecture, culture and cuisine. You Rogelio López-Velez, Madrid, Spain may stroll through Europe’s third-largest city, which serves as the Kristine Morch, Bergen, Norway political, economic and cultural centre of the country. Marc Nicol, Cape Town, South Africa We warmly welcome you to Madrid and are excited that you Elisabet Nielsen, Uppsala, Sweden are part of our annual highlight. Thank you for again making this Hanna Nohynek, Helsinki, Finland congress one of the top scientific events of the year. Eli Perencevich, Iowa City, IA, United States

50 YEARBOOK 2017/2018 ECCMID YEARBOOK 2017/2018 ECCMID 51 Impressions ECCMID 2017

52 YEARBOOK 2017/2018 ECCMID YEARBOOK 2017/2018 ECCMID 53 Professional Affairs Subcommittee Professional Affairs Overview Maurizio Sanguinetti, Rome, Italy, Chair ID members Nur Benzonana, Istanbul, Turkey Julia Anna Bielicki, London, United Kingdom Elena Carrara, Tübingen, Germany Achilleas Gikas, Heraklion, Greece “Supporting the educational and career Alejandro Martin-Quiros, Madrid, Spain development of our members, and creating Malgorzata Mikulska, Genoa, Italy a platform for them to connect with Carlos Palos, Loures, Portugal Jean Paul Stahl, Grenoble, France experienced professionals in their field CM members and establish strong ties, continues Emmi Andersson, Stockholm, Sweden ESCMID/ASM Conference on to be the driving force of our activities.” Ferry Hagen, Nijmegen, Netherlands Polona Maver Vodicˇar, Ljubljana, Slovenia Surbhi Malhotra-Kumar, Antwerp, Belgium Drug Development to Meet the Challenge Maurizio Sanguinetti Professional Affairs Officer for Clinical Hilpi Rautelin, Uppsala, Sweden of Antimicrobial Resistance Microbiology and Infectious Diseases Joanna Verran, Manchester, United Kindom Matthias Willmann, Tübingen, Germany Parity Commission Lisbon, Portugal The past year has been full of changes for ESCMID. The most impor- Maurizio Sanguinetti, Rome, Italy, Chair tant one within Professional Affairs has been the relaunch of the ob- 4 – 7 September 2018 servership programme. This is one of the most popular activities of Angela Huttner, Geneva, Switzerland our society and the ESCMID Executive Committee has gradually in- Alexandra Mailles, Saint-Maurice, France creased its budget every year (by 30% in 2016) and has sponsored Chrysanthi Skevaki, Athens, Greece Programme Committee Including: more than 600 visits since the programme began. As has been the Trainee Association of ESCMID (TAE) Murat Akova, Ankara, TR • Discovery efforts in the face of AMR trend in previous years, we were once again inundated with applica- Aleksandra Barac, Belgrade, Serbia, President-elect tions in 2017. The previous process led to a situation where a large David Ong, Utrecht, Netherlands, President Maiken Arendrup, Copenhagen, DK • Pharmacokinetics and pharmacodynamics part of the 2018 observership budget (about EUR 100,000) had al- Sujata Bhavnani, Schenectady, NY, US • Update on regulatory processes by EMA and FDA ready been spent by November 2017. For this reason, the Executive Marco Cavaleri, London, UK • Breakpoints for new agents Committee decided to stop accepting applications before year-end, Herman Goossens, Edegem, BE • Clinical trial design for AMR and to find an alternative way of managing the observerships to al- David Hooper, Boston, MA, US • Development of new drugs for special populations low a fairer application process and a more sustainable programme. William Hope, Liverpool, UK • Getting AMR research funded To be more inclusive, the new-look observership programme offers both funded and non-funded observerships. The non-funded Sumathi Nambiar, Washington D.C., US • Interactive sessions: bring your drug applications are open throughout the year to all members, regard- John Rex, Wellesley, MA, US development problem and ask! less of age and career stage. Applications for the funded observer- Jesús Rodríguez Baño, Seville, ES Contact: [email protected] ships, for which we will hold two calls annually, are open to young Keith Rodvold, Chicago, IL, US scientist members. This new process will allow us to assess the Michael Sharland, London, UK Find more information and registration information candidates more fairly and award observerships to those who best Judith Steenbergen, Boston, MA, US on our website www.escmid.org/Lisbon2018 demonstrate how the visit to their chosen ESCMID Collaborative Centre (ECC) will improve their own learning as well as benefit their The Mentorship pilot programme has been a success with home institution. The process will undergo consistent evaluation 20 mentorships awarded since the pilot began in 2015. In 2018 we as we strive to make this valuable offering the best that it can be will be relaunching the programme with the emphasis on a more for our members, and to provide this opportunity to bring individu- structured mentorship between a young scientist member and an als together from all over the world to advance healthcare and re- expert in the field of clinical microbiology and infectious diseases. search. We thank our members and ECCs for their understanding We will begin with a limited number of mentorships so keep an eye and continued support during this time of transition. on our website and newsletter to ensure you don’t miss the chance Seven new ECCs from both Europe and the rest of the world to apply. joined us in 2017. The support of our ECCs enables us to offer our Throughout the year, I have had the pleasure of meeting the members an attractive variety of skills and expertise to choose Parity Commission and the Trainee Association of ESCMID (TAE) from when applying for an observership. Through our communica- steering committee. Both groups continue to work on projects to tion with hosts and from the reports we receive from the observ- widen the opportunities available to those in training and in the ers, we are proud to say that the observership programme offers early stages of their career, and to those who could face discrimi- both parties an ideal opportunity to exchange learning, ideas and nation in the field due to gender, age, sexual orientation, race, re- discuss future collaboration. We’re also pleased to see that many gion, religion and/or political beliefs without consideration of their returning observers encourage their institutes to apply to become personal achievements. an ECC, meaning that the community continues to grow and ben- The following pages contain further details about ESCMID’s efit more and more people. professional affairs activities, as does our website.

54 YEARBOOK 2017/2018 ADVERTS YEARBOOK 2017/2018 PROFESSIONAL AFFAIRS 55 ESCMID Collaborative Centres and Observerships www.escmid.org/observerships

Maurizio Sanguinetti ESCMID Professional Affairs Ofﬁ cer [email protected]

The ESCMID Collaborative Centre (ECC) and Ob- of this programme. Observers are able to learn from servership initiative reached an important mile- our ECCs, which have all been carefully selected to stone in 2017 and provided us with the opportunity ensure a high-quality exchange. I’d like to thank our to create a fairer and more sustainable programme. ECCs for their continued support, especially the staff Almost 120 ECCs will be offering both funded and who provide invaluable assistance during the visits. unfunded observerships in 2018, including seven ESCMID appreciates the time and resources the ECCs new ones in Argentina, China, the Republic of Korea, spend on each visit and is grateful for each collabo- Portugal, Sweden, Switzerland and Turkey. With ECCs ration. in almost 40 countries across all fi ve continents, the programme continues to expand with the society and we’d like to warmly welcome our new ECCs and encourage more institutes to join. In 2017 observers visited 17 countries within Europe (fi ve more than last year) and eight outside the region (three more). The table on page 58 shows the top ten hosting centres of 2017. Sweden (16), Germany (15) and the United Kingdom (12) were the most popular countries to visit last year. Of the 16 observers visiting Sweden, 14 went to the ECDC (see the report on page 59). Almost 35% of the total of 118 observers came from countries outside Europe. The top countries of provenance around the globe were Spain and Turkey with 11 each and, showing that our support of international members is continuing to increase, Brazil and Iran, each with nine observers (see map overleaf for observer country of origin). The programme continues to attract more female participants (72) than male (46, Figure 1). The most popular length of visit was between 16 and 31 days with 49 observers taking the opportunity for a longer learning programme whilst 27 observers chose visits of 10 –15 days, with 40 preferring short- er visits of 3 –10 days (Figure 2). We relaunched the application process in 2018 Where ESCMID observers come from ... with funded observerships being offered to ESCMID Young Scientist Members only through two calls per year. There are 50 places available per call and we ... and where they go! request that you prepare the application pack carefully. For full details of the criteria, please visit the observership pages on our website: escmid.org/observerships. All members are eligible to apply for our unfunded observerships throughout the year. Our new-look observership application platform includes an interactive map which makes looking for the right ECC based on core competencies even easier. The end-of-visit reports completed by our observers continue to show the immeasurable benefi ts

56 YEARBOOK 2017/2018 PROFESSIONAL AFFAIRS YEARBOOK 2017/2018 PROFESSIONAL AFFAIRS 57 4% ECDC/ESCMID Observership 2017 41%

39% 33%

61% The European Centre for Disease Prevention and Con- ESCMID and ESCV-supported observers trol (ECDC) hosted a group of 14 ESCMID members who visited ECDC in 2017 for the ESCMID ECDC observership initiative between Ana Cecilia Bardossy, Detroit, MI, United States 22% 4 – 8 September 2017 at the ECDC headquarters in Stockholm, Sweden. These 14 ESCMID observers Harriet Blundell, Staffordshire, United Kingdom were joined by observers from the European Society Pankaj Bhardwaj, Jodhpur, India Figure 1. Gender of Figure 2. Length of Philip Britton, Westmead, Australia observers in 2017 stay in 2017 for Clinical Virology (ESCV) for a five-day orientation Female 16 – 31 days programme designed to introduce the ECDC’s activi- Cristina Costa, Leiria, Portugal Male 10 –15 days ties, role and mandate in supporting public health Catherine Ludden, London, United Kingdom 3 –10 days actions to control and prevent infectious disease in Hasmik Margaryan, Nukus city, Uzbekistan Other the EU and globally. Tomislav Meštrovic´, Samobor, Croatia The scope of the 2017 visit covered the general ac- Duygu Öcal, Ankara, Turkey tivities of the centre, such as surveillance, microbi- Arun Wilson, New Delhi, India ology support, production of scientific advice and David Ong, Rotterdam, Netherlands epidemic intelligence to detect emerging commu- Daniel Thomas-Lopez, Madrid, Spain nicable disease threats to the EU. Observers also Deborah Tong, Suva, Fiji Top 10 ESCMID Collaborative Centres attended presentations on the work of specific programmes at the centre, addressing issues includ- Kyriakos Zaragkoulias, Thessaloniki, Greece ing antimicrobial resistance, vaccine-preventable Visitors Host Department Institute City, Country diseases and influenza. In addition to formal presentations, the programme included several hands-on 14 Marc J. Struelens European Centre for Disease Prevention ECDC Stockholm, Sweden exercises. The presentations and the hands-on ex- and Control ercises facilitated interaction with ECDC experts and 12 Andrej Trampuz Center for Musculoskeletal Surgery Charité – University Medicine Berlin, Germany other observers who gained practical experience in creating rapid risk assessments, interpreting molec- 9 Danilo Lo Fo Wong World Health Organisation WHO regional office for Europe Copenhagen, Denmark ular typing data, integrating typing data in European- level surveillance and public-health decision making. 8 Oriol Manuel Service of Infectious Diseases, Lausanne University Hospital Lausanne, Switzerland Department of Medicine The ESCMID observers travelled to the ECDC from all 7 Jacques F. Meis Clinical Microbiology and Infectious Diseases Canisius Wilhelmina Ziekenhuis (CWZ) Nijmegen, Netherlands over the world; half came from EU member states, 6 Bridget Atkins Bone Infection Unit Nuffield Orthopaedic Centre, Oxford University Oxford, United Kingdom while the other half travelled from the US, Turkey, Hospitals NHS Foundation Trust Uzbekistan, India and Oceania. Their visit reports 5 Marc Mendelson Division of Infectious Diseases and HIV Medicine, Groote Schuur Hospital, Cape Town, South Africa are available on ESCMID’s website. This is the fifth Department of Medicine University of Cape Town year of the ESCMID-ECDC observership initiative 3 Fanny Lanternier Infectious Diseases Unit Necker Hospital Paris, France with feedback from both ECDC staff and ESCMID observers continuing to be positive. Therefore we are 3 Alex W. Friedrich Medical Microbiology and Infection Prevention University Medical Centre Groningen Groningen, Netherlands pleased to report that the ECDC observership programme will continue in 2018 from 3 – 7 September. 3 Jordi Rello Critical Care Department and Clinical Research Vall d’Hebron University Hospital, Barcelona, Spain More information can be found at www.escmid.org/ and Innovation in Pneumonia and Sepsis Barcelona, Catalonia, Spain ECDC_observer and in the advertisement on page 61.

58 YEARBOOK 2017/2018 PROFESSIONAL AFFAIRS YEARBOOK 2017/2018 PROFESSIONAL AFFAIRS 59 WHO/ESCMID Observership 2017 Mentoring www.escmid.org/mentorship

Nine ESCMID observers spent three days at the World Maurizio Sanguinetti Health Organization (WHO) in Copenhagen, Denmark ESCMID Professional Affairs Officer from 24 – 26 October 2017. The visit gave them an in- [email protected] sight into the operations of the organization through informative sessions regarding the special interests The mentorship programme was launched in 2014. Currently Increasing the range of ESCMID Mentorship Centres is important of WHO. It also provided an invaluable networking 27 ESCMID Mentorship Centres (EMCs) are registered with ESCMID to us. If your centre has experience in mentoring or is a centre of opportunity. throughout the world. There are 14 ongoing mentorships and the excellence in a specific area of infectious diseases, clinical micro- progress reports from the mentees have so far been very positive. biology or infection control, please apply to be recognized as an On the first day WHO staff presented the various Two of the main motivations for being mentored are getting ESCMID Mentorship Centre and contribute to the research and ca- activities to observers, with a focus on the division career advice and to acquire specific expertise from a well-estab- reer development of up-and-coming scientists. Applications are of health emergencies and communicable diseases, lished specialist. Any ESCMID young scientist member has the op- easily submitted online at www.escmid.org/mentorship. and lectures about AMR and emergency prepared- portunity to be mentored by a senior expert at one of the EMCs. A Take advantage of this new programme to discover your ness for emerging infectious diseases. On the sec- typical example is a mentee being mentored through their research strengths and fulfil your potential. Look out for the call for applica- ond day, they delved into more specific topics, in- project from the initial phase of approval by the ethics committee tions on our website and in our newsletter. cluding influenza and other respiratory pathogens, through the planned activities of case inclusion, statistical analy- malaria and other vector-borne parasitic diseases, ses and publication. and tuberculosis. On the last day, observers had the In 2018 we will be offering a handful of two-year mentorships opportunity to give a 5-minute presentation about to those with a specific educational aim. Up to EUR 3,000 will be their backgrounds and the context of their work, reimbursed against original receipts for costs incurred over the their perceptions of WHO before and after the visit, maximum two-year period, including telephone bills, telephone and to discuss potential collaborations in the future. conference invoices and travel costs (train, air ticket). All reports from the observers, which can be viewed on our website, are very positive and highlight the value of such collaborations. ESCMID-ECDC Observerships in 2018 In 2017 four ESCMID members from Europe and one each from Indonesia, India, Australia, South Africa and Peru, successfully completed the WHO Regional Visit ECDC and Office for Europe observership, as listed below. find out about the organization! ESCMID-supported observers who visited WHO in 2017 A group of 15 observers (ESCMID members) are offered Tika Adilistya, Balikpapan, Indonesia a five-day programme at the European Centre for Jaykaran Charan, Jodhpur, India Disease Prevention and Control (ECDC) in Stockholm, Sweden. Geoffrey Coombs, Murdoch, Australia 3 – 7 September 2018 Tracy King, Pietermaritzburg, South Africa Applications accepted from: May 2018 Alejandro Martin-Quirós, Madrid, Spain Applicants must be ESCMID Young Scientist Members and Laura Melissa Mori Llontop, Callao, Peru active in the infectious disease and public health fields beyond a regional level. Prajwal Prajwal, Schlieren, Switzerland Stephanie Sian Thomas, Manchester, United Kingdom To apply, visit the ESCMID website. Arkadii Vodianyk, Kiev, Ukraine www.escmid.org/ECDC_Observer www.ecdc.europa.eu

60 YEARBOOK 2017/2018 PROFESSIONAL AFFAIRS YEARBOOK 2017/2018 PROFESSIONAL AFFAIRS 61 ESCMID Parity Commission Trainee Association of ESCMID (TAE)

Maurizio Sanguinetti David Ong ESCMID Professional Affairs Ofﬁcer President of the TAE [email protected] [email protected]

The parity commission’s (PC) primary aim is to pro- assess the current situation and determine what im- The Trainee Association of ESCMID (TAE) aims to improve the train- In 2018 the TAE is collaborating with ESGAP and EUCIC in a new mote fairness in the working environment of all clini- provements need to be made. The second will involve ing in clinical microbiology (CM) and infectious diseases (ID), survey of antimicrobial stewardship and infection control, which cal microbiology and infectious disease profession- communicating formally with identified medical so- and to create a large network of young professionals to facilitate also includes training-related aspects. Furthermore, the TAE plans als. It undertakes its own research and examines cieties and implementing a rational solution, allow- and promote international collaboration and effective use of re- to assess the associations between income, work satisfaction and the research of others to find out what and where ing those who have taken career breaks fair access sources. The TAE responds to concerns of trainees in particular migration desires of (young) medical specialists in different Euro- the problems are, raises awareness of the issues, to career development tools (awards and grants for and the challenges they face, but also represents the interests of pean countries. develops strategies both to address them and to en- instance) leading towards senior posts. young medical specialists who have recently finished their train- Last year the TAE steering committee increased its use of so- courage change, diversity and meritocracy. Closer to The PC continues to be active on its blog, to look ing, medical students, PhD students and other young researchers cial media to share interesting news from CM, ID and other topics home, the parity commission exerts its influence to at disparity due to gender or provenance. It invites within ESCMID. relevant for young professionals and to endorse interaction among increase diversity at ESCMID events and activities, members to contribute their experience of good This past year, TAE steering committee members have rep- peers. We invite you to visit our website (www.escmid.org/tae) including educational courses and workshops, the practice for gender and geographic balance or of be- resented the interests of trainees at several important meetings, and to follow us on Facebook (www.facebook.com/ESCMID.TAE) Summer School and ECCMID itself. Its involvement ing denied access to the professional assets essen- including the annual meetings of the European Union of Medical and Twitter (@TAEscmid). leads to insights, which in turn can be translated into tial to make progress in their career by commenting Specialists’ Medical Microbiology and Infectious Diseases sections, Finally, we sincerely thank all our colleagues for their contin- guidelines for best practice to obtain a balanced pro- on the blog at http://profession-issues.escmid.org. and at those of both the ESCMID Educational and Professional Af- uous feedback and support. Together we can improve our training fessional population. For further information about PC activities, fairs subcommittees. and increase the participation of young professionals in interna- In the period 2010–2016, the ESCMID PC pro- such as publications, projects or simply to contact During ECCMID 2017, the TAE organized the Trainees Day with tional activities. moted a variety of research projects to discover us, please visit the ESCMID website www.escmid.org/ over 115 participants. Round table sessions were held with rec- detailed information about inequality in the sec- parity. ognized experts in CM and ID, who led discussions about career tor of clinical microbiology and infectious diseases development and shared their own work-life experiences. The TAE (CM/ID). These projects focused mostly on gen- awards for Training Achievement were also presented during this Current TAE Steering Committee der balance but highlighted that, due to the grow- event and the Young Investigator Awardees presented their re- David Ong, Rotterdam, Netherlands, President ing mobility of health care workers, discriminatory search accomplishments. Thea-Christin Zapf, Marburg, Germany, Secretary mechanisms based on national origin are also an in- For the first time, TAE representatives attended the ESCMID Cansu Çimen, Istanbul, Turkey, Treasurer creasing problem. Around 15,000 physicians are af- Summer School 2017 to inform participants about TAE’s activities. fected each year and with around 150,000 qualified Furthermore, we co-organized a successful Postgraduate Educa- Zaira Palacios Baena, Seville, Spain, Social Media Officer foreign doctors presently working in Europe, there is tion Course about “Antibiotic therapy in practice” in November 2017. Caroline Rönnberg, Stockholm, Sweden, Networking Officer still very little information available so far on the ac- Between June and September 2017, the TAE launched a sur- Aleksandra Barac, Belgrade, Serbia, Communication Officer tual professional and living conditions of expatriate vey among European trainees focusing on the topics of supervi- Müge Cevik, Edinburgh, United Kingdom, Education Officer doctors. sion, mentorship and management. Up to 400 respondents par- The PC is therefore carrying out a study specifi- ticipated in this survey and the main findings will be shared at cally aimed at filling this gap. The study includes a ECCMID 2018. Our interest to study these specific areas arose from literature review on inter-European mobility of phy- earlier observations obtained during a previous TAE survey, the re- sicians and a set of in-depth interviews with clinical sults of which were published in 2016 and 2017 (PMID: 27704297 microbiologists and infectious disease specialists and PMID: 28233138, respectively). who have spent or are spending a working period in another European country. The study is expected to be completed in May 2018. Despite the fact that for many years women have made up the majority of medical school gradu- ates, leadership positions in academic and other medical research institutions are overwhelmingly dominated by male physicians and microbiologists. It seems that gender parity is not advancing as it should be in medical academic settings. The PC will therefore conduct a two-stage process whose goal is to review and reform in a rational and balanced fashion the application restrictions currently responsible for the continued imbalance observed in senior/leadership positions in clinical microbiology and infectious disease workplaces. The first stage will Picture of TAE day 2017

62 YEARBOOK 2017/2018 PROFESSIONAL AFFAIRS YEARBOOK 2017/2018 PROFESSIONAL AFFAIRS 63 ESCMID Observerships ESCMID International Affairs Subcommittee (EIAS) Update and improve your clinical

and laboratory skills! In 2017/2018 the international affairs subcommittee has contin- • 2nd Gulf Congress of Clinical Microbiology and Infectious ued to initiate and nurture relationships on all continents. Thanks Diseases (GCCMID) from 1 – 4 November 2017 in Bahrain to the subcommittee’s continued efforts ESCMID has been able to During the congress organized by the Saudi Society for Medical The ESCMID Observership programme is an opportunity extend its reach and presence across the world. Microbiology and Infectious Diseases (SSMMID), Maurizio San- for ESCMID members to visit an ESCMID Collaborative Over the past year the ESCMID international affairs subcom- guinetti gave a talk about infections related to therapy with bio- Centre and to learn good clinical and laboratory practice. mittee has continued to develop ESCMID’s international relations. logical agents and Paul Verwej held a presentation about prophy- www.escmid.org/observerships Strong links have been forged on every continent, particularly in laxis for Aspergillus in haematological cancer. the Far East, Middle East, India, the Russian Federation and South • Ministerial Conference on TB and Global Health from 17 – 18 and Central America, by contributing to or organizing conferences, November 2017 in Moscow, Russia symposia and training as well as establishing ESCMID collaborative Delia Goletti gave a talk on biomarkers for tuberculosis in HIV-TB centres. coinfected patients. Cooperation throughout Europe is well established, while the • 41st Congress of Indian Association of Medical Microbiolo- society’s partnerships on the North American continent need to gists, IAMM (Microcon) from 22 – 26 November 2017 in Ranchi, be further reinforced. On 6 October 2017 ESCMID and the Associa- India tion of Medical Microbiology and Infectious Disease Canada (AMMI Surbhi Malhotra-Kumar gave a presentation about the trans- Canada) signed a memorandum of understanding. Potential areas mission of plasmid-borne antimicrobial resistance and Katy of cooperation between the two societies are contributions to the Jeannot discussed mechanisms of resistance to polymyxins in scientific programmes of annual meetings, the development of Gram-negative bacteria. medical guidelines and the organization of conferences, education • 30th International Congress of Chemotherapy and Infection courses and observerships. from 24 – 27 November 2017 in Taipei, Taiwan Giuseppe Cornaglia stepped down as chairperson to follow ESCMID co-organized a symposium entitled Drug resistance in other pursuits and we wish him well in his endeavours. the microbial world, which included a lecture by Giuseppe Cor- naglia on antibacterial resistance, a talk by ESCMID President Past Events Mario Poljak on antiviral resistance and a presentation by Alan ESCMID Mentorships • 18th congress of the Asociación Panamericana de Infectología Hauser on new therapeutic approaches for bacterial infections. (API) from 16 – 20 May 2017 in Panama City, Panama In addition Mario Poljak gave a keynote address reviewing vac- ESCMID representatives participated in a co-organized sympo- cines for HPV. Improve your career sium. Juan A. Pineda discussed new paradigms in hepatitis C and Dominique Salmon held a talk about new approaches in the and skills and benefit treatment of chronic hepatitis B. • 18th International Congress of Microbiology from 29 – 31 August from experienced 2017 in Tehran, Iran Luis Martínez-Martínez gave a talk on phenotypic and genotypic professionals in the methods for the detection of carbapenemases in enterobacteria, on susceptibility testing of polymyxins and heteroresistance, persistence and toxin-antitoxin systems. He also participated field of CM and ID. in panel discussions on the management of microbial resistance and the identification of antimicrobial drugs from natural ESCMID members can be mentored by an ESCMID resources. mentorship centre by a mentor from our pool of centres. • ASM/ESCMID Conference on Drug Development to Meet the Chal- lenge of Antimicrobial Resistance from 6 – 8 September 2017 in International Affairs subcommittee www.escmid.org/mentorships Boston, United States Jesús Rodríguez Baño, Seville, Spain, Chairperson (ad interim) ESCMID co-sponsored the conference with the American Society Giuseppe Cornaglia, Verona, Italy, Former Chairperson for Microbiology (ASM) and William Hope acted as ESCMID Co-Chair. Middle East: Atef Shibl, Riyadh, Saudi Arabia • Annual Meeting of the Korean Society of Clinical Microbiology India: Camilla Rodrigues, Mumbai, India in October 2017 in Seoul, South Korea ESCMID co-organized and co-chaired a symposium on the shift Latin America: Maria Virginia Villegas, Cali, Colombia of management paradigm in the clinical microbiology labora- Australia / South Pacific: David L. Paterson, St. Lucia, Australia tory. Katja Seme talked about laboratory automation, ESCMID ex- China: Qiu Haibo, Nanjing, China ecutive committee member Maurizio Sanguinetti discussed the Japan: Kazuhiro Tateda, Tokyo, Japan 24-hour laboratory and Sunjoo Kim from the Korean society held Russian Federation: Roman S. Kozlov, Smolensk, Russian Federation a lecture on responsible management. Mario Poljak co-chaired Euro-Asian Republics: Adalat Abdullajev, Baku, Azerbaijan the symposium and held a keynote lecture on the ongoing revo- lution in clinical microbiology. South East Asia: Po-Ren Hsueh, Taipei, Taiwan

64 YEARBOOK 2017/2018 ADVERTS YEARBOOK 2017/2018 INTERNATIONAL NETWORKING 65 Awards and Grants ESCMID research and travel grants

We received 162 applications for 2018 ESCMID research grants, which are awarded for outstanding research projects by young ESCMID members. Fif- ESCMID supports young clinicians, research- teen colleagues with basic or applied research pro- ISF Sepsis Award ers and established scholars with awards and jects were chosen. Special thanks to all the experts grants to acknowledge past achievements and and reviewers (listed on page 70 – 71), who did a provide an incentive for future accomplishments. tremendous job evaluating all these submissions. ESCMID supports its members’ research projects As happens every year, one of the research Vinod Kumar from the Department of Genetics at the and training in the disciplines of clinical microbiol- grant recipients with a highly rated project proposal University of Groningen is the winner of this year’s ogy and infectious diseases with a total of some is also awarded the ESCMID/FEMS Fellowship and ISF Sepsis Award for his abstract about a functional half a million euros every year. About EUR 330,000 this year it goes to Natalia Muñoz-Wolf from Trinity genomics approach to identify novel susceptibility of that is reserved for its grant programme to fi- Excellence Award College Dublin, Ireland, for her project investigating pathways for fungal infections. nance several promising research projects. ESCMID the role of Mal/TIRAP and the Mal-S180L SNP as de- is pleased to announce the recipients of the soci- terminants of susceptibility to pneumococcal dis- ety’s awards and grants for the year 2018. ease and antipneumococcal vaccine efficacy. You can ﬁnd details of all recipients of awards and Our most prestigious award is the ESCMID Award for In addition ESCMID supports junior colleagues research grants for 2018 on the following pages. Excellence in Clinical Microbiology and Infectious with merit-based travel grants and free registra- Diseases. The ESCMID executive committee select- tion to enable them to attend ECCMID. We are giving ed Dimitrios P. Kontoyiannis from the University of 91 young scientists travel grants and free registra- Texas MD Anderson Cancer Center in Houston, United tion for ECCMID 2018 in Madrid, where they will pre- States, as well as Claudio Viscoli from the University sent the results of their work. ESCMID also supports of Genova in Italy to receive this year’s distinction its members early in their careers with attendance in recognition of their achievements. Kontoyiannis grants for other ESCMID conferences, the Summer is an international expert in clinical and experimen- School, post-graduate educational courses and oth- tal mycology. His research group is credited with er educational and/or scientific events. sustained and impactful contributions to medical and translational mycology through advances in antifungal pharmacology, the study of host defences against fungi, novel diagnostics, clinical trials, dedicated mentoring, organizational service and life-saving patient care. Viscoli is an expert for infec- Young Investigator Awards tious disease in children and adults with special expertise in infections in the compromised host, fungal infections, infections in cancer and neutropenia, infections in liver transplant recipients, opportunis- The executive committee selected two recipients for tic infections in HIV and HIV vertical transmission. this year’s Young Investigator Awards for research The awards pay tribute to their accomplishments in in clinical microbiology and infectious diseases. the field. Congratulations! The winners are Evgeny A. Idelevich, a clinical microbiologist from the University Hospital Münster, Germany, who has a strong interest in rapid sepsis diagnostics and susceptibility testing; and James R. 1 Price, a research lecturer at the Brighton and Sus- 3 sex Medical School, United Kingdom who develops strategies to prevent healthcare-associated infections by multidrug-resistant organisms. We congratulate the winners and look forward to their valuable TAE Awards contributions to the society in the coming years.

The two winners of this year’s TAE Awards for training achievements are Robbert Bentvelsen, a resident in clinical microbiology at the University Medi- cal Center in Leiden, Netherlands, and Maroun Sfeir, infectious diseases trainee at the Weill Cornell Medi- cal College in New York, United States. 2

66 YEARBOOK 2017/2018 AWARDS & GRANTS YEARBOOK 2017/2018 AWARDS & GRANTS 67 ESCMID Award for Excellence ESCMID Young Investigator Awards in Clinical Microbiology for Research in Clinical Microbiology and Infectious Diseases and Infectious Diseases

Claudio Viscoli, University of Genova and Dimitrios P. Kontoyiannis, University of Texas Evgeny A. Idelevich, Münster, Germany James R. Price, Brighton, United Kingdom Ospedale Policlinico San Martino, Italy M. D. Anderson Cancer Center, United States Evgeny Idelevich is a board-certifi ed specialist for James Price, a National Institute for Health Research Claudio Viscoli is an expert in the fi eld of infectious disease in chil- Dimitrios Kontoyiannis is one of the world’s leading authorities on clinical microbiology at the Institute of Medical Mi- clinical lecturer in infectious diseases and microbiolo- dren and adults with special expertise in infections in the com- invasive mycoses and an innovative investigator in this critical area. crobiology at the University Hospital Münster in Ger- gy at the Brighton and Sussex Medical School, United promised host, fungal infections, infections in cancer and neutro- He is the Texas 4000 Distinguished Endowed Professor for Cancer many. He is a very promising, up-and-coming young Kingdom, possesses the full range of talents needed penia, infections in liver transplant recipients and opportunistic Research and Deputy Head Research in the Division of Internal Med- scientist physician, whose excellent translational to succeed in clinical research and has already built infections in HIV and HIV vertical transmission. icine at The University of Texas MD Anderson Cancer Center. He is research on the development of novel methods for an impressive CV of completed and ongoing studies. He attended medical school at the University of Genova and also an adjunct professor at Baylor College of Medicine and Univer- infectious disease diagnostics has already found use James’s research is focused on the prevention after graduation worked for 15 years in the paediatric infectious sity of Houston College of Pharmacy in Houston, Texas. He received in everyday laboratory practice. Evgeny has a strong of healthcare-associated infections, including S. au- disease department at the G. Gaslini Institute in Genova, Italy, fi rst his medical degree summa cum laude from the National and Kapo- interest in the translational approach used to develop reus and other multidrug-resistant organisms. He as a fellow at the post-graduate school of infectious disease and distrian University of Athens in Greece. He also completed a post- new methods to diagnose infectious diseases. combines developing his research interests with then as attending physician in the same department. As the posi- doctoral clinical research fellowship at his current institute, fol- His research focuses on the rapid diagnosis of completing specialist training in infectious diseases tion of consultant in infectious disease in Italy was basically non- lowed by training in internal medicine at Baylor College of Medicine, bloodstream infections and sepsis, rapid susceptibil- and microbiology. His work utilizes whole-genome existent at that time, Viscoli and others became pioneers in this also in Houston, TX, where he served as a chief medical resident. ity testing and the potential of novel antimicrobials to sequencing and epidemiological data to evaluate car- new fi eld, particularly in haematology, oncology and HSCT. A short Dimitrios Kontoyiannis has authored more than 520 peer- treat multidrug-resistant microorganisms. He has de- riage, acquisition and transmission of pathogens in period as an observer at the Sloan Kettering Research Center in reviewed manuscripts and been invited to give over 320 lectures veloped novel principles of sepsis diagnostics and de- healthcare settings with the aim of developing inter- New York allowed him to further understand the role of the infec- at international conferences and prestigious institutions in the tection of multidrug-resistant organisms, which have ventions to reduce nosocomial infections. James led tious disease consultant. US and abroad. He serves as an associate editor for Mycoses and led to patent applications and technology transfer a detailed prospective study evaluating a nosocomial Claudio Viscoli has focused his research activity mainly on Journal of Infection and sits on the editorial boards of many jour- from academia to industry. Some methods are cur- outbreak of MRSA that led to novel insights into S. au- adult and paediatric immunocompromised host infections and nals. He is one of the two most highly cited investigators in the rently in further development, funded by the German reus epidemiology and the biology of dominant MRSA has an H-index of 46 (Scopus), number of citations: 9385, total IF: area of mycology with over 36.000 citations (Google Scholar, ac- Ministry of Education and Research, and some have lineages. He successfully gained competitive funding 1162. Claudio Viscoli is author of over 330 original articles or re- cessed December 22, 2017) with an H index of 93. already been introduced into routine diagnostics. from the British Infection Association to undertake a views in peer review journals (Pub-Med; Scopus) and 21 books or His research group is credited with sustained and impactful Evgeny is an active member of the society. He novel project; and his current research projects are chapters. He is also a reviewer for several journals including JID, contributions to medical and translational mycology through ad- participates in the ESCMID study group for blood- generating some very exciting results that may chal- CID, Lancet ID and CMI. vances in antifungal pharmacology, the study of host defences stream infections and sepsis (ESGBIS) where he lenge our current perceptions of S. aureus infection. He is currently the designated member for Italy on the adviso- against fungi, novel diagnostics, clinical trials, dedicated mentor- currently coordinates activities for an international James is currently contributing to the development of ry board of EUCIC (European Committee on Infection Control, Presi- ing, organizational service and life-saving patient care. Dimitrios survey of diagnostics of bloodstream infections in evidence-based ESCMID guidelines on management dent of SITA – Società Italiana per la Terapia Antinfettiva Italiana Kontoyiannis is the recipient of many awards including most re- European laboratories. Within this project he has built of multidrug-resistant Gram-negative organisms. (Italian society for antimicrobial therapy) and, among other roles, cently being named a fellow of both the American Academy of Mi- a strong network of clinical microbiologists in 26 Eu- consultant to the scientifi c advisory board for anti-infectives of the crobiology and the American Association for the Advancement of ropean countries. James will receive his award during the ESCMID committee for medicinal products for human use (CHMP) of EMA, Science (AAAS). Young Investigator Awards session from 11:30 – the European Medicine Agency. For the last 20 years Dimitrios Kontoyiannis has led a highly Evgeny will receive his award during the ESCMID 12:30 on Monday, 23 April 2018 in Hall G. James will He leads the infectious diseases team at the University of productive and innovative research programme in both clinical Young Investigator Awards session from 11:30 – give a talk on Unravelling Staphylococcus aureus Genoa where his main activities are teaching, patient care and re- and translational mycology. His investigations in clinical mycology 12:30 on Monday, 23 April 2018 in Hall G and will give transmission: a game of catch or hide and seek? search as well as giving presentations around the world. encompass studies in epidemiology, natural history, prognosis, a presentation on Acceleration of microbiological and management of nearly all opportunistic fungal infections af- diagnostics: it’s time to rethink! He will receive his award on Sunday, 22 April 2018 at a dedicated fl icting immunocompromised cancer patients. awards session at ECCMID in Madrid. During the ceremony he will give his recipient lecture Changing epidemiology and manage- He will receive his award on Sunday, 22 April 2018 at a dedicated ment of fungal infections in the compromised host. awards session at ECCMID in Madrid. During the ceremony he will give his recipient lecture How transformation in care of haematological cancers will impact the invasive fungal disease ecosystem.

68 YEARBOOK 2017/2018 AWARDS & GRANTS YEARBOOK 2017/2018 AWARDS & GRANTS 69 ESCMID Research Grants

The following ESCMID members have received a research grant in 2018 for the indicated project.

Mehreen Anjum Emma Birnie Vítor Borges Maria João Catalão Mireia Coscollá Department of Veterinary Division of Infectious Diseases, Department of Infectious Microbiology and Immunology, Institute for Integrative Systems and Animal Sciences, Center for Experimental Diseases, National Health University of Lisbon, Biology (I2sysBio), University of Copenhagen, Molecular Medicine & Center Institute Doutor Ricardo Jorge, Lisbon, Portugal University of València, Copenhagen, Denmark for Travel and Tropical Medicine, Lisbon, Portugal Paterna, Spain Academic Medical Center, Project: Decoding the peptidoglycan Project: Elucidating the dynamics Amsterdam, Netherlands Project: TraSyph – tracing the patterns associated with beta- Project: Genetic basis of host of foodborne transmission of Treponema pallidum genetic lactams hypersusceptibility pathogen interaction of ESBL plasmids using a gnotobiotic Project: In search of melioidosis footprints associated with in drug-resistant Mycobacterium tuberculosis in West Africa mice model in Nigeria, an environmental, syphilis outcomes and stages tuberculosis clinical and sero-epidemiological surveillance of Burkholderia pseudomallei

Sara Dias Geneviève Garriss Carsten Kröger Nico Lachmann Christian Lesterlin Department of Neurology, Karolinska Institutet, Department of Microbiology, Hannover Medical School, Department of Molecular Centre of Infection and Immunity Stockholm, Sweden Moyne Institute of Preventive Hannover, Germany Microbiology and Structural Amsterdam (CINIMA) Medicine, Trinity College Dublin, Biochemistry, National Academical Medical Centre, Project: Role of bacteriophages Ireland Project: iPSC-derived Center for Scientiﬁ c Research, University of Amsterdam, in the evolution and virulence macrophages targeting antibiotic Lyon, France Amsterdam, Netherlands of the human pathogen Project: Are regulatory RNAs resistant Pseudomonas Streptococcus pneumoniae crucial for antibiotic aeruginosa in cystic ﬁ brosis Project: Acquisition and Project: The role of sex steroid resistance and virulence establishment of drug resistance hormones in bacterial meningitis gene expression in through bacterial gene transfer the nosocomial pathogen Acinetobacter baumannii?

ESCMID / FEMS Fellow

Natalia Muñoz-Wolf Santiago Ramón-García Anca Lelia Riza Davide Roncarati Amaia Zuñiga-Ripa Department for Biochemistry Vice-chancellor of Research, Department of Infectious Department of Pharmacy Department of Microbiology and Immunology, Trinity University of Zaragoza, Diseases, Radboud University and Biotechnology, and Parasitology, Biomedical Science Institute, Zaragoza, Spain Medical Centre, University of Bologna, Italy University of Navarra, Trinity College Dublin, Ireland Nijmegen, Netherlands Pamplona, Spain Project: Identifi cation of novel Project: The essential trans- Project: Investigating the therapies for diffi cult-to-treat Project: Tuberculosis in Romania: criptional regulator HP1043 of Project: Role of erythritol, role of Mal/TIRAP and cystic fi brosis pulmonary improved drug-resistance Helicobacter pylori: a new glutamate, lactate and glycerol in the Mal-S180L SNP as infections caused by myco- detection and molecular target for the design of a new the genital tropism of Brucella determinants of susceptibility bacteria, using an innovative epidemiological understanding antibacterial drug to pneumococcal disease technology: synergy screens of through whole genome and antipneumococcal vaccine clinically approved drugs sequencing (DRD-ME) e f fi c a c y

70 YEARBOOK 2017/2018 AWARDS & GRANTS YEARBOOK 2017/2018 AWARDS & GRANTS 71 ESCMID TAE Awards for Training Achievements

Robbert Bentvelsen Maroun Sfeir Resident Clinical Microbiology Infectious Diseases trainee Leiden University Medical Center Weill Cornell Medical College Leiden, Netherlands New York, United States ESCMID eLibrary

ISF-ESCMID Sepsis Award

View all ECCMID abstracts, posters, presentations, webcasts...

Vinod Kumar, Groningen, Netherlands is still lacking. That is why Vinod and colleagues performed the The International Sepsis Forum (ISF) is a non-profi t, public Ameri- fi rst genome-wide association analysis (GWAS) using the largest can charity with the mission to improve outcomes for patients with candidaemia cohort of European ancestry to date to identify sus- sepsis. Its award gives the recipient USD 500 and the opportunity ceptibility genes. They assessed the cytokine production capacity to present their work orally during a session jointly organized by in different cellular systems following stimulation with three differ- ISF and ESCMID. ent opportunistic fungal pathogens: Candida albicans, Aspergillus This year’s winner is Vinod Kumar from the Department of Ge- fumigatus and Cryptococcus neoformans. The study suggests that netics at the University of Groningen, Netherlands. He submitted genetic loci which affect cytokine responses to C. albicans can an abstract about a functional genomics approach to identify novel partly explain an individual’s disease susceptibility. susceptibility pathways for fungal infections. In his research, Vi- Following his PhD in Germany in the fi eld of host-pathogen nod aims to identify human genes and molecular mechanisms that interactions, Vinod moved to the Netherlands (UMCG, Groningen) Explore all ESCMID’s regulate appropriate immune responses and may contribute to to further investigate the complex process of host-pathogen inter- susceptibility to sepsis and other infectious diseases. As tradition- actions from a genetics point of view to understand the mecha- Fastest access to ECCMID educational events, conferences al approaches to fi nd causal genes for sepsis and other infectious nisms of infections. As part of his project, he established strong material on ECCMIDlive and its congress ECCMID. diseases have not been very successful, Vinod and colleagues collaborations with clinicians and computational scientists to per- www.eccmidlive.org www.escmid.org/eLibrary take advantage of state-of-the-art technologies, simultaneously form studies using large patient and population-based cohorts. He assessing genetics, transcriptomics and immune-profi ling in the demonstrated that genetic variations contribute the most to the context of host-pathogen interaction using population-based co- variability in innate immune responses to infectious agents, and horts and integrating the obtained data with patient-genetics. Vi- he identifi ed susceptibility genes to fungal sepsis in the European nod is discovering new avenues for further investigation and tar- population. geted drug discovery for sepsis. For the paper he will present at ECCMID, Vinod and colleagues Vinod Kumar will present his abstract after receiving his award investigated susceptibility factors for Candida albicans, the most during the session Trending topics in sepsis on Sunday, common opportunistic fungal pathogen causing candidaemia 22 April 2018 at 17:00 in Hall A at the 28th ECCMID in Madrid. bloodstream infection. Not all at-risk patients develop candidaemia, suggesting that genetics infl uences their susceptibility. Cytokines play a critical role in anti-fungal host defence, but a comprehensive approach to understanding the genetic architecture of cytokine responses against fungi and their role in fungal disease susceptibility

72 YEARBOOK 2017/2018 AWARDS & GRANTS YEARBOOK 2017/2018 ADVERTS 73 Finances

“As a non-profi t organization, ESCMID supports New accounting standard for non-profi t organizations As we announced last year, we have started preparing for the tran- many scientifi c and educational activities and is able sition to a new accounting standard, GAAP FER 21, which will im- to provide grants for research projects and obser- prove the informative value and transparency of the society’s performance reports. While ESCMID will postpone the switch to GAAP vership visits. This is only possible because of a solid FER 21 by one year to prepare its systems for the change, it has fi nancial basis. In 2017 the society returned to a already started to build its internal control system. In addition the positive fi nancial result on an operational level as a society has introduced a code of conduct and implemented clear policies on procurement, expenses and communication. Finally the result of its successful activities.” society has initiated an audit of its information technology systems to better control its costs. Alex W. Friedrich ESCMID Treasurer Outlook: science and professional development remain central [email protected] The budgeted expenses for 2018 are similar to 2017. The largest share of ESCMID’s expenses in 2018 will again be spent on the portfolios that allow the society to fulfi l its mission. As may be seen ESCMID can look back on a fi nancially well managed year. With an from Figure 3 below, scientifi c affairs will again account for the Figure 1. Comparison of Figure 3. Budgeted expenses operational surplus of EUR 438,886, the society can not only ab- 1.2 million expenses for key activities largest portion of the society’s expenses, followed by education by category for the year 2018 sorb last year’s shortfall, it can also rebuild the reserves for the in 2016/2017 (EUR) and professional affairs. The costs of the society’s administration, Scientifi c Affairs years to come. To improve transparency, ESCMID improved the 1.0 million 2016 including fi nance, communication, publishing and the executive Education 2017 Professional Affairs bookkeeping of the funding of its study group activities. The funds committee, will comprise about 30% of total spending. Mgt/Finance/HR/Admin 0.8 million allocated to the ESCMID study groups were moved from the general Executive Committee capital of the organization to the assigned capital to create a more Communication 0.6 million transparent picture of the association’s fi nances. Publications Membership Services 0.4 million Best fi nancial result ever 4% The executive committee’s decision to bring the organization of 0.2 million 5% the society’s annual congress in-house had a positive impact on 7% 29% the society’s fi nancial results: thanks to ECCMID 2017 in Vienna, 0 ESCMID achieved the highest operating profi t from its congress in 7% its history. Education

Publications 7% Scientific Affairs Scientific Costs declined Communications While the overall expenses for key activities decreased by 3% to AffairsProfessional EUR 2.8 million in 2017, expenses for the education portfolio were up 18% from last year. This refl ects greater expenditure as the so- 18% 23% ciety insourced the processing of its educational courses. The in- Figure 2. Actual expenses come from educational courses increased in line with the budgeted 1.2 million 2017 for key activities spending on them. Spending in scientifi c affairs shows a decline in versus budget 2017 2017 against the exceptionally high outlay on research grants in 1.0 million Budget 2017 2016. However scientifi c affairs in 2017 still accounted for the larg- Expenses 2017 est share of fi nancial resources of all activities. Spending on com- 0.8 million munications and professional affairs showed minimal reductions. 0.6 million

0.4 million

0.2 million

0 Education Publications Scientific Affairs Scientific Communications Professional AffairsProfessional

74 YEARBOOK 2017/2018 FINANCES YEARBOOK 2017/2018 FINANCES 75 RZ_Ins_Future Congresses_19-20_Pfad.pdf 1 06.02.18 08:50

Forthcoming Events

More detailed information can be foundwww.escmid.org on the ESCMID website:

Postgraduate Education Courses and Workshops 21 – 24 Oct Capacity-building Workshop: Receive state-of-the-art knowledge from expert educators. Metagenomics in the Diagnostic Laboratory Gather hands-on experience in your ﬁeld of interest. Groningen, Netherlands Discuss your work with senior and peer colleagues. ESCMID Postgraduate Technical Workshop

25 – 26 May Colistin: the Last Barrier for MDR 7 – 9 Nov Better Methods for Clinical Studies in Beijing, People’s Republic of China Infectious Diseases and Clinical Microbiology: ESCMID Postgraduate Education Course a Hands-on Workshop Seville, Spain 12 – 14 Sep Infection in the Elderly: ESCMID Postgraduate Technical Workshop the Next Challenges La Tronche, France ESCMID Postgraduate Education Course ESCMID Summer School An intense one-week course covering diverse topics in the 14 – 16 Sep ESCMID/ASID Course on Infectious infection ﬁeld. The high faculty-student ratio and the high level Diseases in Pregnant Women, Fetuses of interactivity make it so popular. and Newborns Sydney, Australia 1 – 7 Jul 17th ESCMID Summer School ESCMID Postgraduate Education Course Paris, France

C 19 – 21 Sep Antifungal Resistance in Candida

M and Aspergillus: ESCMID Conferences from Clinic to Clinical Laboratory Get the latest news about your ﬁeld of work delivered from selec- Y Delhi, India ted experts. Exchange ideas with your colleagues on hot topics. CM ESCMID Postgraduate Technical Workshop MY 4 – 7 Sep ESCMID/ASM Conference on Drug

CY 25 – 28 Sep Diagnostic Microbiology: MALDI-TOF, Development to Meet the Challenge of Bacterial Genomics, Metagenomics, Antimicrobial Resistance CMY Automation and Molecular Microbiology Lisbon, Portugal K Lausanne, Switzerland ESCMID Postgraduate Technical Workshop 26 – 27 Sep Conference on Antimicrobial Resistance: from Bench to Practice 25 – 28 Sep Antimicrobial Susceptibility Testing and Havana, Cuba Surveillance: from Laboratory to Clinic – a EUCAST, ESGARS and EPASG Perspective Bochum, Germany Future ECCMIDs ESCMID Postgraduate Technical Workshop 13 – 16 Apr 29th ECCMID 2019 Amsterdam, Netherlands 27 – 28 Sep Management of Mycobacterial Infections and Associated Comorbidities 18 – 21 Apr 30th ECCMID Rome, Italy 2020 Paris, France ESCMID Postgraduate Education Course

11 – 13 Oct Acute Bacterial CNS Infections of the Brain Munich, Germany ESCMID Postgraduate Education Course

76 YEARBOOK 2017/2018 FORTHCOMING EVENTS YEARBOOK 2017/2018 FORTHCOMING EVENTS 77 A big thank you to all our dedicated reviewers!

ECCMID abstract reviewers (603) Carmeli, Yehuda, Israel Eremeeva, Marina, United States Haug, Jon Birger, Norway Koulenti, Despoina, Greece Marwick, Charis, United Kingdom Otelea, Dan, Romania Rogers, Benjamin, Australia Abdala, Edson, Brazil Carratala, Jordi, Spain Ergönül, Önder, Turkey Hedberg, Maria E., Sweden Kozlov, Roman S., Russian Federation Maschmeyer, Georg, Germany Otter, Jonathan, United Kingdom Rohde, Holger, Germany Abrahão, J.S., Santos Abrahão, Brazil Carrico, Joao Andre, Portugal Ergunay, Koray, Turkey Hell, Markus, Austria Kramer, Tobias, Germany Massey, Ruth, United Kingdom Pachon-Diaz, Jeronimo, Spain Roilides, Emmanuel, Greece Achermann, Yvonne, Switzerland Castelli, Francesco, Italy Esposito, Susanna, Italy Henriques, Mariana, Portugal Kresken, Michael, Germany Mastrantonio, Paola, Italy Pagani, Leonardo, Italy Ronat, Jean-Baptiste, France Aguado Garcia, Jose Maria, Spain Cataldo, Maria Adriana, Italy Favennec, Loic, France Herrmann, Jean Louis, France Krutova, Marcela, Czech Republic Mathers, Amy, United States Pagano, Livio, Italy Rosado, Maria Manuela, Italy Akan, Hamdi, Turkey Cattoir, Vincent, France Feil, Edward, United Kingdom Higgins, Paul G, Germany Kuijper, Ed J., Netherlands Matteelli, Alberto, Switzerland Paixão, Paulo, Portugal Rossen, John W. A., Netherlands Akova, Murat, Turkey Cerar Kišek, Tjaša, Slovenia Fernandez Ruiz, Mario, Spain Hirsch, Hans H., Switzerland Kurt, Özgür, Turkey Matuschek, Erika, Sweden Pal, Tibor, United Arab Emirates Rossolini, Gian Maria, Italy Akyar, Isin, Turkey Cercenado, Emilia, Spain Fernandez-Hidalgo, Nuria, Spain Hoen, Bruno, Guadeloupe Kurzai, Oliver, Germany Maver Vodicˇar, Polona, Slovenia Palos, Carlos, Portugal Ruiz-Camps, Isabel, Spain Alanio, Alexandre, France Cervera, Carlos, Canada Fernández-Rodríguez, Amparo, Spain Hoiby, Niels, Denmark Lackner, Michaela, Austria Mcconnell, John S., United Kingdom Pano-Pardo, José Ramón, Spain Rumbaugh, Kendra P., United States Allegaert, Karel, Netherlands Chalker, Victoria, United Kingdom Filip, Roxana, Romania Hooper, David C., United States Larsen, Anders Rhod, Denmark Mediannikov, Oleg, France Papadopoulos, Antonios, Greece Rupali, Priscilla, India Allerberger, Franz, Austria Chiodini, Peter, United Kingdom Fingerle, Volker, Germany Horcajada, Juan P., Spain Lass-Flörl, Cornelia, Austria Megraud, Francis, France Papaparaskevas, Joseph, Greece Rybak, Michael J., United States Almirante Gragera, Benito, Spain Chkhartishvili, Nikoloz, Georgia Firsov, Alexander A., Russian Federation Horgan, Mary, Ireland Laurent, Frederic, France Meis, Jacques F., Netherlands Paredes, Roger, Spain Saegeman, Veroniek, Belgium Alvarez Martinez, Miriam José, Spain Chrobak-Chmiel, Dorota, Poland Fischer, Nicole, Germany Hovius, Joppe Willem Robert, Netherlands Lautenschlager, Irmeli, Finland Melano, Roberto, Canada Pascual Hernandez, Alvaro, Spain Salmon-Ceron, Dominique, France Amer, Fatma A., Egypt Chryssanthou, Erja, Sweden Fischer, Thea Kølsen, Denmark Howe, Robin, United Kingdom Le Monnier, Alban, France Meletiadis, Joseph, Greece Patel, Robin, United States Salzberger, Bernd, Germany Andersson, Emmi, Sweden Ciofu, Oana, Denmark Foster, Timothy J., Ireland Hrabak, Jaroslav, Czech Republic Lebeaux, David, France Mermel, Leonard A., United States Paul, Mical, Israel Sanchez Garcia, Miguel, Spain Andes, David, United States Cisneros Herreros, Jose Miguel, Spain Fournier, Pierre-Edouard, France Hsueh, Po-Ren, Taiwan Lebech, Anne-Mette, Denmark Metan, Gokhan, Turkey Paul, Malgorzata, Poland Sander, Leif Erik, Germany Andreoletti, Laurent, France Claas, Eric, Netherlands Francois, Bruno, France Hu, Bijie, China Leblebicioglu, Hakan, Turkey Mevius, Dik Johan, Netherlands Pea, Federico, Italy Sands, Anita, Switzerland Angkasekwinai, Nasikarn, Thailand Coenye, Tom, Belgium Friedland, Jon S., United Kingdom Humphreys, Hilary, Ireland Lee, Susanne, United Kingdom Mielke, Martin, Germany Peixe, Luisa Maria Vieira, Portugal Sanglard, Dominique, Switzerland Antonelli, Guido, Italy Cohen, Jonathan, United Kingdom Friedrich, Alexander W., Netherlands Humphries, Romney M., United States Leeflang, Mariska MG, Netherlands Migliori, Giovanni Battista, Switzerland Pena Miller, Rafael, Mexico Sanguinetti, Maurizio, Italy Antoniadou, Anastasia, Greece Coia, John E., United Kingdom Frimodt-Moller, Niels, Denmark Hunfeld, Klaus-Peter, Germany Leegaard, Truls Michael, Norway Mikulska, Malgorzata, Italy Pereira, José Manuel, Portugal Savelkoul, Paul H.M., Netherlands Ardanuy Tisaire, Carmen, Spain Collignon, Peter, Australia Gaia, Valeria, Switzerland Huovinen, Pentti, Finland Lehours, Philippe, France Minarovits, Janos, Hungary Pereira Jr., Jose Paulo, Brazil Schaffer, Kirsten, Ireland Arendrup, Maiken Cavling, Denmark Coque, Teresa, Spain Gaillat, Jacques, France Hussein, Khetam, Israel Leib, Stephen L., Switzerland Miragaia, Maria, Portugal Perencevich, Eli, United States Schneider, Elena, Australia Arends, Joop E., Netherlands Cornely, Oliver A., Germany Galan Ladero, Maria Angeles, Spain Huttner, Benedikt, Switzerland Leibovici, Leonard, Israel Miranda, Isabel, Portugal Peter, Silke, Germany Schön, Thomas, Sweden Arikan-Akdagli, Sevtap, Turkey Cortez, Joana, Angola Galani, Irene, Greece Ieven, Margareta, Belgium Lens, Sabela, Spain Miró Meda, José María, Spain Petersdorf, Sabine, Germany Schouten, Jeroen, Netherlands Aronoff, David, United States Costelloe, Ceire, United Kingdom Gales, Ana, Brazil Imbert, Christine, France Letaief, Amel, Tunisia Mischnik, Alexander, Germany Petersen, Eskild, Denmark Schrenzel, Jacques, Switzerland Ascioglu, Sibel, Turkey Couet, William, France Garau, Javier, Spain Inan, Asuman Sengöz, Turkey Lewis, Russell, Italy Modrow, Susanne, Germany Petrosillo, Nicola, Italy Schwartz, Stefan, Germany Autenrieth, Ingo B., Germany Courcol, Rene J., France Garbino, Jorge, Switzerland Inglis, Timothy John Jay, Australia Li, Jian, Australia Mondelli, Mario Umberto, Italy Peyron, Francois, France Schweizer, Marin, United States Baddley, John, United States Cretu, Carmen-Michaela, Romania Garcia Vidal, Carolina, Spain Irving, William, United Kingdom Liapikou, Adamantia, Greece Mongkolsapaya, Juthathip, United Kingdom Pierard, Denis, Belgium Seifert, Harald, Germany Balcazar, Jose Luis, Spain Cuenca-Estrella, Manuel, Spain Gardy, Jennifer, Canada Ison, Michael G, United States Lina, Bruno, France Monto, Arnold, United States Pletz, Mathias, Germany Seleem, Mohamed, United States Balode, Arta Olga, Latvia Cutler, Sally Jane, United Kingdom Garnacho-Montero, José, Spain Isturiz, Raul, United States Lina, Gérard, France Montravers, Philippe, France Poirel, Laurent, Switzerland Seme, Katja, Slovenia Barzon, Luisa, Italy Dagan, Ron, Israel Gastmeier, Petra, Germany Jankovic´ Makek, Mateja, Croatia Lindsay, Jodi, United Kingdom Moore, Catherine, United Kingdom Poljak, Mario, Slovenia Sener, Alper, Turkey Bassetti, Matteo, Italy Dagne, Daniel Argaw, Switzerland Gatermann, Sören G., Germany Janson, Håkan, Sweden Lionakis, Michail S., United States Morace, Giulia, Italy Pomba, Maria Constança, Portugal Sester, Martina, Germany Becker, Karsten, Germany Daikos, George L., Greece Gaustad, Peter, Norway Jarlier, Vincent Pascal, France Ljungman, Per, Sweden Moran-Gilad, Jacob, Israel Poulakou, Garyfallia, Greece Severini, Carlo, Italy Beeching, Nicholas John, United Kingdom Dancer, Stephanie J., United Kingdom Gavazzi, Gaetan, France Jarraud, Sophie, France Lockhart, Shawn R., United States Morch, Kristine, Norway Pournaras, Spyros, Greece Sharland, Mike, United Kingdom Begovac, Josip, Croatia Day, Nick, United Kingdom Geerlings, Suzanne E., Netherlands Jaulhac, Benoît, France Löffler, Bettina, Germany Moreno Guillen, Santiago, Spain Poyart, Claire, France Sherwin, Catherine, United States Benzonana, Nur, Turkey De Angelis, Giulia, Italy Gerding, Dale N., United States Jeanes, Annette, United Kingdom Longtin, Yves, Canada Moser, Claus, Denmark Presterl, Elisabeth, Austria Shirtliff, Mark Everett, United States Beovic´, Bojana, Slovenia De Lencastre, Herminia, Portugal Gerner-Smidt, Peter, United States Jensen, Jorgen Skov, Denmark Lopez-Cortes, Luis Eduardo, Spain Mouton, Johan Willem, Netherlands Price, James, United Kingdom Sintchenko, Vitali, Australia Beraud, Guillaume, France Dedic, Kanita, Bosnia And Herzegovina Ghisetti, Valeria, Italy Johansen, Helle Krogh, Denmark López-Lozano, José-María, Spain Mueller, Nicolas, Switzerland Proctor, Richard A., United States Sipahi, Oguz Resat, Turkey Bertelli, Claire, Switzerland Del Campo, Rosa, Spain Giamarellos-Bourboulis, Evangelos, Greece Johansson, Anders, Sweden Lopez-Medrano, Francisco, Spain Muller, Anouk, Netherlands Prymula, Roman, Czech Republic Skevaki, Chrysanthi, Germany Bhimraj, Adarsh, United States Delogu, Giovanni, Italy Giamarellou, Helen, Greece Jones, Ronald N., United States López-Vélez, Rogelio, Spain Munoz, Patricia, Spain Pujol, Miquel, Spain Skiada, Anna, Greece Birgand, Gabriel, United Kingdom Derendorf, Hartmut, United States Giannitsioti, Efthymia, Greece Junie, Lia Monica, Romania Lora-Tamayo, Jaime, Spain Murillo, Oscar, Spain Pulcini, Céline, France Skov, Robert Leo, Germany Bitam, Idir, Algeria Deresinski, Stan, United States Gikas, Achilleas, Greece Justesen, Ulrik Stenz, Denmark Lortholary, Olivier, France Musso, Didier, French Polynesia Ramage, Gordon, United Kingdom Slavin, Monica, Australia Blumberg, Emily, United States Dessau, Ram B., Denmark Giske, Christian, Sweden Kaasch, Achim, Germany Lucet, Jean-Christophe, France Mutters, Nico Tom, Germany Ramirez, Mario N., Portugal Snyder, Lori, United Kingdom Bogaerts, Pierre, Belgium Dettenkofer, Markus, Germany Glocker, Erik, Germany Kahl, Barbara C., Germany Lück, Christian, Germany Naas, Thierry, France Rasigade, Jean-Philippe, France Snydman, David R., United States Bonnet, Eric, France Di Giandomenico, Antonio, United States Gniadkowski, Marek, Poland Karatuna, Onur, Turkey Ludovisi, Serena, Italy Naber, Kurt G., Germany Ratho, Radha Kanta, India Snygg-Martin, Ulrika, Sweden Bonomo, Robert A., United States Diekema, Daniel J., United States Goletti, Delia, Italy Katragkou, Aspasia, United States Lumbreras, Carlos, Spain Nagy, Elisabeth, Hungary Rautelin, Hilpi, Sweden Sogni, Philippe, France Bonten, Marc J.M., Netherlands Dierikx, Cindy Maria, Netherlands Gonzalez-Martin, Julian, Spain Kaye, Keith S., United States Lundgren, Jens D., Denmark Nathavitharana, Ruvandhi, United States Rawson, Timothy, United Kingdom Solaja, Bogdan, Serbia Borghi, Elisa, Italy Dinh, Aurélien, France Gonzalez-Zorn, Bruno, Spain Keller, Nathan, Israel Lutsar, Irja, Estonia Nation, Roger L., Australia Raymaekers, Marijke, Belgium Solbrig, Marylou V., United States Bosshard, Philipp, Switzerland Docobo Perez, Fernando, Spain Gopalakrishnan, Ramachandran, India Kern, Winfried V., Germany Macgowan, Alasdair P., United Kingdom Netea, Mihai Gheorghe, Netherlands Razonable, Raymund, United States Solé, Candela, Switzerland Bottieau, Emmanuel, Belgium Donelli, Gianfranco, Italy Gould, Kate, United Kingdom Kernif, Tahar, Algeria Mackenzie, Colin R., Germany Neyrolles, Olivier, France Reigadas, Elena, Spain Sonnevend, Agnes Maria, Bowker, Karen E., United Kingdom Donker, Tjibbe, United Kingdom Gradoni, Luigi, Italy Kiertiburanakul, Sasisopin, Thailand Maertens, Johan, Belgium Nicol, Mark Patrick, South Africa Reinwald, Mark, Germany United Arab Emirates Braun, Dominique, Switzerland Dorlo, Thomas, Netherlands Greub, Gilbert, Switzerland Kilani, Badreddine, Tunisia Magiorakos, Anna-Pelagia, Sweden Nielsen, Elisabet, Sweden Rello, Jordi, Spain Soriano, Alex, Spain Brisse, Sylvain, France Drgona, Lubos, Slovakia Groll, Andreas H., Germany Klein, Matthias, Germany Malhotra-Kumar, Surbhi, Belgium Nir-Paz, Ran, Israel Renzoni, Adriana, Switzerland Souli, Maria, Greece Brouwer, Matthijs Christian, Netherlands Dryden, Matthew, United Kingdom Grossi, Paolo Antonio, Italy Klimko, Nikolay, Russian Federation Manuel, Oriol, Switzerland Nohynek, Hanna M., Finland Retamar Gentil, Pilar, Spain Speth, Cornelia, Austria Bruce, Kenneth, United Kingdom Duarte, Raquel, Portugal Grundmann, Hajo, Germany Klingspor, Lena, Sweden Maraolo, Alberto Enrico, Italy Noori, Teymur, Sweden Reuter, Sandra, Germany Spiller, Brad, United Kingdom Brüggemann, Roger, Netherlands Dubberke, Erik, United States Guardabassi, Luca, Denmark Kluytmans, Jan A.J.W., Netherlands Marchand, Sandrine, France Nordmann, Patrice, Switzerland Rey, David, France Srinivasan, Arjun, United States Bruisten, Sylvia, Netherlands Dumke, Roger, Germany Gudiol, Carlota, Spain Kluytmans-Van Den Bergh, Marjolein, Marco Reverte, Francesc, Spain Norrby-Teglund, Anna, Sweden Richards, Guy, South Africa Stahl, Jean Paul, France Buchheidt, Dieter, Germany Dwyer, Dominic, Australia Gudiol Munte, Francisco, Spain Netherlands Mardani, Masoud, Iran Norredam, Marie, Denmark Richtmann, Rosana, Brazil Stavenger, Robert A., United States Budimir, Ana, Croatia Eckmann, Christian, Germany Guery, Benoit, Switzerland Kocak Tufan, Zeliha, Turkey Mares, Mihai, Romania Nseir, Saadalla, France Rieg, Siegbert, Germany Steer, Andrew, Australia Butaye, Patrick, Saint Kitts And Nevis Eggimann, Philippe, Switzerland Guinea Ortega, Jesus, Spain Köck, Robin, Germany Martin-Quiros, Alejandro, Spain Oggioni, Marco Rinaldo, United Kingdom Rinaldo, Christine Hanssen, Norway Stefani, Stefania, Italy Calandra, Thierry, Switzerland Egli, Adrian, Switzerland Gutiérrez-Gutiérrez, Belén, Spain Kocsis, Béla, Hungary Martinez, Esteban, Spain Olesen, Bente, Denmark Robert-Gangneux, Florence, France Steinmann, Joerg, Germany Calbo, Esther, Spain Ekelund, Oskar, Sweden Gyssens, Inge C., Netherlands Kofteridis, Diamantis, Greece Martinez, Miguel J., Spain Oliver, Antonio, Spain Rodloff, Arne C., Germany Stensvold, Christen Rune, Denmark Cambau, Emmanuelle, France Endimiani, Andrea, Switzerland Hannan, Margaret, Ireland Kortbeek, Titia M., Netherlands Martinez Martinez, Jose Antonio, Spain Oprea, Cristiana, Romania Rodrigo, Carlos, Spain Stupicˇa, Dasa, Slovenia Canton Moreno, Rafael, Spain Ene, Luminita, Romania Hansen, Sonja, Germany Koskiniemi, Sanna, Sweden Martinez-Martinez, Luis, Spain Orth-Hoeller, Dorothea, Austria Rodrigues, Camilla, India Sundqvist, Martin, Sweden Capobianchi, Maria Rosaria, Italy Epaulard, Olivier, France Harbarth, Stephan Juergen, Switzerland Kostyanev, Tomislav, Belgium Martins, Marta Sofia, Ireland Osorio, Jorge, United States Rodríguez-Baño, Jesús, Spain Sundsfjord, Arnfinn, Norway

78 YEARBOOK 2017/2018 REVIEWERS YEARBOOK 2017/2018 REVIEWERS 79 Suputtamongkol, Yupin, Thailand Willmann, Matthias, Germany Grossi Paolo Antonio, Italy Skurnik Mikael, Finland Tacconelli, Evelina, Germany Wilmer, Alexander, Belgium Guardabassi Luca, Denmark Snyder Lori, United Kingdom What ESCMID can do for you Tamarozzi, Francesca, Italy Xian-Zhi, Li, Canada Gutierrez Maximiliano, United Kingdom Sonnevend Agnes Maria, Tambic´ Andraševic´, Arjana, Croatia Yusuf, Erlangga, Belgium Hall-Stoodley Luanne, United States United Arab Emirates Tarr, Philip E., Switzerland Zaccarin, Matthias, Denmark Hasse Barbara, Switzerland Spaan András N., United States around the clock Tassios, Panayotis T., Greece Zajkowska, Joanna Maria, Poland Herrmann Jean Louis, France Spiller Brad, United Kingdom Tateda, Kazuhiro, Japan Zeitlinger, Markus, Austria Higgins Paul G, Germany Stahl Jean Paul, France Tattevin, Pierre, France ˇZidovec Lepej, Snjezˇana, Croatia Hilpert Kai, United Kingdom Stavenger Robert A., United States Taylan Özkan, Aysegül, Turkey Zimmerli, Werner, Switzerland Huttner Angela, Switzerland Steininger Christoph, Austria Tedeschi, Sara, Italy Zingg, Walter, Switzerland Ison Michael G, United States Tacconelli Evelina, Germany dy Grou Templeton, Kate, United Kingdom Zinkernagel, Annelies, Switzerland Jalalvand Farshid, Sweden Tadokoro Carlos, Brazil Stu ps Tenover, Fred C., United States Jensen Jorgen Skov, Denmark Tattevin Pierre, France Terhes, Gabriella, Hungary ESCMID research grant Kaasch Achim, Germany Tokajian Sima T., Lebanon Theuretzbacher, Ursula, Austria reviewers (162) Kahl Barbara C., Germany Toleman Mark Alexander, United Kingdom ID ourses & W CM C or C ks Thomsen, Trine Rolighed, Denmark Akova Murat, Turkey Kocsis Béla, Hungary Torres Antoni, Spain E h o Timsit, Jean-Francois, France Akyar Isin, Turkey Koedel Uwe, Germany Tulkens Paul M., Belgium p s Tobudic, Selma, Austria Allerberger Franz, Austria Koskiniemi Sanna, Sweden Upton Mathew, United Kingdom Tokajian, Sima T., Lebanon Almirante Gragera Benito, Spain Kostyanev Tomislav, Belgium Valiente Mendez Adoracion, Spain Toleman, Mark Alexander, United Kingdom Alvarez Martinez Miriam José, Spain Kozlov Roman S., Russian Federation Viveiros Miguel, Portugal Tomasz, Alexander, United States Ardanuy Carmen, Spain Kruger Peter, Australia Weese Scott, Canada Torres, Antoni, Spain Arends Joop E., Netherlands Laurent Frederic, France Werner Guido, Germany Obse Torres, Carmen, Spain Balcazar Jose Luis, Spain Leibovici Leonard, Israel Williams Craig, United Kingdom rv s er ce s Tsakris, Athanassios, Greece Balode Arta Olga, Latvia Li Jian, Australia Wu Min, United States n h e ip r s Tschudin Sutter, Sarah, Switzerland Beeching Nicholas John, United Kingdom Longtin Yves, Canada Yang Qi-wen, China e f Tsiodras, Sotirios, Greece Bengoechea Jose, Ireland Lopes Bruno, United Kingdom Yusuf Erlangga, Belgium n o

Tulkens, Paul M., Belgium BERAUD Guillaume, France Mares Mihai, Romania Zajkowska Joanna Maria, Poland C Tumbarello, Mario, Italy Bergström Sven, Sweden Martins Marta Soﬁa, Ireland Zinkernagel Annelies, Switzerland Turnidge, John D., Australia Bielicki Julia Anna, United Kingdom Mathers Amy, United States Tzanakaki, Georgina, Greece Blazquez Jesus, Spain Matteelli Alberto, Italy Ullmann, Andrew J., Germany Bonten Marc J.M., Netherlands McClean Siobhan, Ireland Unemo, Magnus, Sweden Borghi Elisa, Italy Megraud Francis, France Upton, Mathew, United Kingdom Bothamley Graham, United Kingdom Miragaia Maria, Portugal Vaheri, Antti, Finland Brisse Sylvain, France Morace Giulia, Italy Valiente Mendez, Adoracion, Spain Brouwer Matthijs, Netherlands Moran-Gilad Jacob, Israel

t Van Bambeke, Francoise, Belgium Bruce Kenneth, United Kingdom Moser Claus, Denmark l n

a o

Van Belkum, Alex, France Buchrieser Carmen, France Mouton Johan Willem, Netherlands o r h G

Van De Veerdonk, Frank, Netherlands Butaye Patrick, Saint Kitts and Nevis Munro Carol, United Kingdom c & S

Van Der Gast, Christopher, United Kingdom Cambau Emmanuelle, France Murillo Oscar, Spain s r

d e

Van Der Hoek, Wim, Netherlands Canton Moreno Rafael, Spain Murphy Cormac, Ireland a m

w m Van Der Meer, Jos W.M., Netherlands Carlet Jean, France Nathavitharana Ruvandhi, United States A u S Van Ingen, Jakko, Netherlands Carmeli Yehuda, Israel Neyrolles Olivier, France Van Lieshout, Lisette, Netherlands Chalker Victoria, United Kingdom Norrby-Teglund Anna, Sweden Van Sorge, Nina, Netherlands Charpentier Xavier, France Oggioni Marco Rinaldo, United Kingdom Vandekerckhove, Linos, Belgium Ciofu Oana, Denmark Oliver Antonio, Spain Vandenberg, Olivier, Belgium Coenye Tom, Belgium Pachon-Diaz Jeronimo, Spain Vandenesch, François, France Coque Teresa M., Spain Pea Federico, Italy Vatcheva-Dobrevska, Rossitza, Bulgaria Cortez Joana, Cambodia Peixe Luisa Maria Vieira, Portugal Veloo, Alida, Netherlands Costelloe Ceire, United Kingdom Pena Miller Rafael, Mexico

P s Venditti, Mario, Italy Couet William, France Pierard Denis, Belgium u p b i Venier, Anne-Gaëlle, France Cutler Sally Jane, United Kingdom Poirel Laurent, Switzerland l h ic s Verbon, Annelies, Netherlands Cytryska Małgorzata, Poland Poulakou Garyfallia, Greece a r ti to Viale, Pierluigi, Italy Day Nicholas, Thailand Presterl Elisabeth, Austria on en s M Villegas, Maria Virginia, Colombia del Campo Rosa, Spain Proctor Richard A., United States Viscoli, Claudio, Italy Delogu Giovanni, Italy Ramirez Mario N., Portugal Visser, Caroline, Netherlands Descoteaux Albert, Canada Rasigade Jean-Philippe, France Vitrat, Virginie, France Di Giandomenico Antonio, United States Raymaekers Marijke, Belgium

n Viveiros, Miguel, Portugal Dinh Aurélien, France Rello Jordi, Spain o J i Von Müller, Lutz, Germany Dobrindt Ulrich, Germany Retamar Gentil Pilar, Spain o t b ia Vos, Margreet C., Netherlands Docobo Perez Fernando, Spain Rodrigo Carlos, Spain P c la so Voss, Andreas, Netherlands Donker Tjibbe, United Kingdom Rosado Maria Manuela, Italy tf As orm ee Wagenlehner, Florian M.B., Germany Dorlo Thomas, Netherlands Rossen John W. A., Netherlands Train Walker, Timothy, United Kingdom Doucet Populaire Florence, France Rossolini Gian Maria, Italy Walsh, Thomas J., United States Egli Adrian, Switzerland Rupnik Maja, Slovenia E C UC UCI Wang, Minggui, China Endimiani Andrea, Switzerland San Millan Alvaro, United Kingdom AST & E Wechsler-Fördös, Agnes, Austria Fernandez-Barat Laia, Spain Sanchez Garcia Miguel, Spain Weese, Scott, Canada Foster Timothy J., Ireland Satrom Pal, Norway Wejse, Christian, Denmark Friedland Jon S., United Kingdom Savelkoul Paul, Netherlands Wensing, Annemarie, Netherlands Geoghegan Joan, Ireland Schaffer Kirsten, Ireland Werner, Guido, Germany Giamarellos-Bourboulis Evangelos, Greece Schlaberg Robert, United States Westh, Henrik, Denmark Giannitsioti Efthymia, Greece Schneider Elena, Australia Widmer, Andreas F., Switzerland Giske Christian, Sweden Sherwin Catherine, United States Wilcox, Mark H., United Kingdom Goletti Delia, Italy Shirtliff Mark Everett, United States Wilder-Smith, Annelies, Singapore Gonzalez-Zorn Bruno, Spain Sipahi Oguz Resat, Turkey Wilﬂingseder, Doris, Austria Greub Gilbert, Switzerland Siu L.K., Taiwan, Republic of China Williams, Craig, United Kingdom Grobusch Martin P., Netherlands Skevaki Chrysanthi, Germany www.escmid.org

80 YEARBOOK 2017/2018 REVIEWERS YEARBOOK 2017/2018 ECCMID 81

RZ_Inserat_ESCMID_Clock_2018.indd 1 14.03.18 16:34 Special thanks go to microbiologist and photographer Ángel Ros Die who let us use his photographs.

My name is Ángel Ros Die and I work as a microbiologist at the Microbiology Service of the Univer- sity Hospital Dr. Peset in Valencia, Spain. My hobby, photography, has been with me for many years and in the department, with the collaboration of all my colleagues, I have been able to put together a comprehensive collection of more than 5,000 scientiﬁ c photographs. I have obtained prizes (3rd in 2010, 2014 and 2nd in 2016) in the scientiﬁ c photography contest of the Faculty of Sciences of the National University of Distance Education in Madrid. I exhibited some of my photographs under the title “Microbiology in images” at the Faculty of Medicine of the University of Valencia. A selection of my pictures can be viewed on my website: www.angelrosdie.com

ESCMID Yearbook ESCMID would like to thank be liable for any errors or Annual publication of the Mateja Poljšak-Prijatelj and inaccuracies in this publi- European Society of Marko Kolenc from the Institute cation. Opinions expressed Clinical Microbiology and of Microbiology and Immunol- are those of the contributing Infectious Diseases ogy in Ljubljana, Slovenia. authors. We are grateful that they let Editorial ofﬁ ce us use their electron Manuscripts and copyright Chantal Britt microscopic images of rota- The editorial team welcomes virus, adenovirus, rhabdovirus your manuscripts, graphics ESCMID and orthomyxovirus. and photographs for Executive Ofﬁ ce publication, especially from P.O. Box 214 Printing company ESCMID Study Groups, 4010 Basel, Switzerland Hofmann Druck, collaborators and third parties. [email protected] Emmendingen, Germany Copyright for articles accepted for publication is shared Visual conception Distribution and between ESCMID and the Flux Design Studios, circulation number author(s). Basel, Switzerland The ESCMID Yearbook is distributed to members and Copyright © European Society Photographers interested people at of Clinical Microbiology Ángel Ros Die, international conferences. and Infectious Diseases 2018. Valencia, Spain Circulation: 12,000. All rights reserved. Non-commercial reproduction Adriano Biondo, Change of address authorized, subject to Basel, Switzerland Notice of change of acknowledgment of source. Thomas Ecke, address can be given online Berlin, Germany at www.escmid.org. Robert Hausmann, Editorial statement Basel, Switzerland Despite careful editing and Hans Runesson, setting, ESCMID, Flux Design Växjö, Sweden and Hofmann Druck cannot

82 YEARBOOK 2017/2018 CREDITS ESCMID www.escmid.org Executive Ofﬁce P.O. Box 214 4010 Basel Switzerland