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Compounds

Connecting Australia’s chemistry researchers with the global bioscience research community.

Compounds Australia provides access to critical infrastructure and expertise to ensure flexible, efficient, reproducible Open access libraries and cost effective compound management, supporting Compounds Australia Structure Portal (CASPeR) was biological characterisation of compounds throughout the launched in early 2016 and enables researchers to browse drug discovery pipeline. or search the ‘Open’ Compound Collections via a web portal. This provides researchers with access to up-to-date Our role information such as individual chemical properties. Established in 2008, Compounds Australia remains Australia’s Find out more at compoundsaustralia.com/casper only integrated compound management facility. This highly specialised facility enables health and medical researchers worldwide to outsource compound and natural product management and logistics. This drives drug discovery and ‘Compounds Australia is the only facility translational research efforts, through: of its kind in Australia that could manage • sample lodgement and storage chemical libraries required for high • specialised formatting into assay-ready microplates throughput screening.’ • access to unique robotic and liquid handling platforms Former Universities Australia Chair, and Vice-Chancellor and President of • a sample quality control program University of Western , Professor Barney Glover, National Press Club, March 2016 – quoting CTx CEO, Mr Warwick Tong. • large-scale data handling • programming and customisation of proprietary software • data tracking at all points of processing. Our services About GRIDD Compounds are curated, either in microtubes or Compounds Australia is part of the Griffith Institute for microplates, under industry-standard storage conditions Drug Discovery (GRIDD). GRIDD tackles devastating diseases to maintain their integrity for an extended shelf life. using the unique Compounds Australia and NatureBank Our equipment includes: resources, and an extensive global network of partners. We thank our supporters including AEGIUM, Cancer Therapeutics • five TTP Labtech comPOUND® stores with total capacity CRC, the Clem Jones Foundation, GHIT-Japan, Medicines to hold 600,000 microtubes for Malaria Venture (MMV), Parkinson’s , Perry • two Hamilton ASM Platestores with total capacity to Cross Spinal Research Foundation, and the Queensland and hold 4,200 microplates Australian Government. We are proud to foster the next • multiple liquid handling platforms able to provide nanolitre generation of drug discovery scientists. (Labcyte Echo® 550) and microlitre (Agilent VPrep/Bravo) quantities of samples in multiple assay-ready formats Compounds Australia members • four dedicated robotic platforms with integration to centrifuge, sealer, de-sealer and barcode tracking. Australian Regen BioPharma Cancer Therapeutics CRC RMIT University Children’s Cancer Institute St Vincent’s Institute of Processing workflows: Children’s Medical Medical Research • Microtube solubilisation and transfer into microplates. Research Institute University of CSIRO University of • Microplate replication in 96, 384 and 1536 plate formats. University of New England • Plate to plate cherry-picking in single- and multi-volume formats. University of Contact us Moana Simpson, Operations Manager • Generate dose response curves via source and MecRx (Pictured below) intermediate concentrations and designing custom plate Medicines for Malaria Venture University of Professor Jennifer Martin, GRIDD Director layouts specific to customer needs. University of Compounds Australia • Access to ​specialised soft​ware that ​allows combination Parma University Walter and Eliza Hall Institute Griffith Institute for Drug Discovery screening formats to compare a drug or other compound Peter MacCallum Cancer Centre of Medical Research Building N75, Griffith University rapidly at a specific dose to look for synergistic or QIMR Berghofer Medical Research Institute Don Young Road, Nathan Qld 4111, Australia antagonistic effects. Queensland University E | [email protected] • Data tracking at all points of processing. of Technology P | +61 7 3735 4448 @CmpdsAus compoundsaustralia.com CRICOS No. 00233E J001477 00233E No. CRICOS