From: ITNDaily on behalf of Werle, Laura Subject: Mount Sinai In the News - September 30, 2016 Date: Friday, September 30, 2016 2:06:09 PM Attachments: ATT00002.txt

In the News September 30, 2016

Nature – September 30 Inflammation in Patients With Cushing Disease — Claire Greenhill Circulating levels of proinflammatory cytokines are increased in patients with Cushing disease, both during active disease and after remission, according to new data published in Clinical Endocrinology. These findings demonstrate that cytokine levels are increased in patients after remission of Cushing disease, which could explain the persistent increased risk of cardiovascular-related death. The study, led by Eliza Geer, MD, a professor of endocrinology at the Icahn School of Medicine at Mount Sinai, notes that more studies are needed to determine why levels of IL-6 and IL-1β remain elevated after remission of Cushing disease. - Eliza Geer, MD, Associate Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Neurosurgery, Icahn School of Medicine at Mount Sinai Learn more: http://www.nature.com/nrendo/journal/vaop/ncurrent/full/nrendo.2016.170.html

WCBS – September 29 ‘Artificial Pancreas’ Expected To Make Life Easier, Healthier For Type 1 Diabetes Patients — Max Gomez A groundbreaking new device could change the lives of millions of people living with diabetes. Federal regulators just approved an artificial pancreas that can monitor and administer insulin. The key is a computer algorithm that does those calculations faster and more accurately than a patient can. “It looks at the numbers from a moment to moment basis, and it will proactively predict what is going to happen next and make clinical decisions that cannot be done at that rate. You would have to be standing and staring at your glucose monitor day and night,” said Carol Levy, MD, an associate professor of endocrinology, diabetes and bone disease at the Icahn School of Medicine of Mount Sinai. - Carol J Levy , M.D. , Associate Professor, Endocrinology, Diabetes and Bone Disease, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine of Mount Sinai Learn more: http://newyork.cbslocal.com/2016/09/29/artificial-pancreas/

WCBS – September 29 Study Finds 30 Percent Of Women Suffer From Fear Of Childbirth — Kristine Johnson A new study reveals there are many women who suffer from a serious phobia about giving birth. Researchers from the University of Michigan found as many as 30 percent of women suffer from a fear of childbirth, and that it can be so significant that it impacts their daily lives. Shari Lusskin, MD, a clinical professor of psychiatry and obstetrics at the Icahn School of Medicine at Mount Sinai, said there are varying degrees of tocophobia. Dr. Lusskin said the fear of not being in control is common with tocophobia, but early intervention can help women regain some of that control, which can reduce anxiety leading to healthier, happier pregnancies. - Shari Lusskin, MD, Clinical Professor, Psychiatry, Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: http://newyork.cbslocal.com/2016/09/28/childbirth-fear-tocophobia/

Kaiser Health News – September 30 Most Hospital Palliative Care Programs Are Understaffed — Michelle Andrews Most hospitals offer palliative care services that help people with serious illnesses manage their pain and other symptoms and make decisions about their treatment, while providing emotional support and assistance in navigating the health system. But hospital programs vary widely, and the majority fail to provide adequate staff to meet national guidelines, a recent study found. Study coauthor Diane Meier, MD, director of the Center to Advance Palliative Care at The Mount Sinai Hospital, said she wasn’t surprised by the low numbers. “There are no regulatory or accreditation requirements that enforce the staffing guidelines,” Dr. Meier said. - Diane Meier, MD, Professor, Geriatrics and Palliative Medicine, Medicine, Vice Chair, Public Policy, Icahn School of Medicine at Mount Sinai, Director, Center to Advance Palliative Care Learn more: http://khn.org/news/most-hospital-palliative-care-programs-are-understaffed/

Boston Globe – September 29 Is Marijuana A Gateway Drug? — David Scharfenberg The strength of claims that marijuana is a “gateway drug” has long been debated. Part of the difficulty in coming up with a definitive answer to the gateway question, researchers say, is that there is no way to conduct a randomized experiment with humans. But there have been animal experiments that provide some evidence for a gateway effect. Yasmin Hurd, PhD, a professor of neuroscience and psychiatry at Icahn School of Medicine at Mount Sinai, one of the researchers involved in one such study, said the THC-exposed rats experienced changes in the nucleus accumbens portion of the brain, which plays an important role in processing motivation and reward — changes that could make them more susceptible to heroin abuse. “People sometimes try to say that marijuana is a ‘safe drug,’ ” said Hurd, a professor of psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai in New York. “I think it’s a little naive.” - Yasmin Hurd, PhD, Professor, Psychiatry, Neuroscience, Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai Learn more: https://www.bostonglobe.com/metro/2016/09/29/marijuana-gateway-drug-the-simple- answer-maybe/zxuZVzEMIPNRf5Idlnx4XJ/story.html

WPIX – September 29 Hope for New Sickle Cell Anemia Treatment — Kirstin Cole For many adult Sickle Cell Anemia patients, risky bone marrow transplants are the only hope for relief from the intense pain and lethargy the disease causes. “We’ve only had bone marrow transplants for adults very recently because it’s safer in kids. In the 70s the life expectancy was 18. Now we quote people somewhere in the 50s,” said Jeffrey Glassberg, MD, associate director of the Mount Sinai Comprehensive Sickle Cell Program. But there is hope for a new treatment in the form of gene therapy. “With gene therapy, you get your own bone marrow as a transplant. They take that marrow out and the fix it and give it back to you,” says Dr. Glassberg. - Jeffrey Glassberg, MD, Assistant Professor, Emergency Medicine, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, Associate Director of The Mount Sinai Comprehensive Sickle Cell Program Learn more: No web link available.

Everyday Health – September 29 6 Ways Weight Loss Can Help Control Diabetes — Marie Suszynski Maintaining a healthy weight has its obvious health benefits—but it can also help you better manage your type 2 diabetes. “This is why lifestyle change through diet and exercise is the best treatment for type 2 diabetes,” says Deena Adimoolam, MD, assistant professor of medicine, endocrinology, diabetes, and bone disease at the Icahn School of Medicine at Mount Sinai. - Deena Adimoolam, MD, Assistant Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://www.everydayhealth.com/hs/diabetes-guide-managing-blood-sugar/how-losing- weight-helps/

New York Magazine’s The Cut – September 29 Why Am I Always Tired? — Susan Rinkunas You may feel like the walking dead, but before you assume that you have a medical condition or a vitamin deficiency, take a good, hard look at your lifestyle, says Shanna Levine, MD, a primary care physician and clinical instructor of medicine at the Icahn School of Medicine at Mount Sinai. If you do have saintly sleep habits but your partner or family members say that you snore, that’s worth bringing up to your doctor, too. It’s possible that you have a condition called sleep apnea, which makes you stop breathing periodically, Dr. Levine says. - Shanna Levine, MD, Instructor, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://nymag.com/thecut/2016/09/why-am-i-always-tired.html

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Stephanie Sherman To: [email protected] ([email protected]) Subject: Mount Sinai In The News - September 29, 2016 Date: Thursday, September 29, 2016 12:40:14 PM Attachments: ATT00002.txt

In the News September 29, 2016

KTBS-TV – September 28 Secondhand Smoke More Insidious Than Thought Nonsmokers can be exposed to secondhand cigarette smoke without realizing it, and be unaware that they are at increased risk for lung cancer and heart disease, a new study suggests. The discovery highlights the need for a more accurate way to assess secondhand smoke exposure than having patients fill out questionnaires. "A crucial finding of this study is that nonsmokers are exposed to secondhand smoke without even realizing it," said lead researcher Dr. Raja Flores. He is chair of thoracic surgery at the Icahn School of Medicine at Mount Sinai. The researchers used blood levels of cotinine, a byproduct of nicotine, as a marker for secondhand smoke exposure in more than 20,000 nonsmokers. - Raja Flores, MD, Steven and Ann Ames Professorship in Thoracic Surgery, Icahn School of Medicine at Mount Sinai, System Chair, Thoracic Surgery, Mount Sinai Health System Learn more: http://www.ktbs.com/story/33268450/secondhand-smoke-more-insidious-than-thought

Newsmax – September 28 Progress Made in Tests for Dementia Cause in NFL Players A separate study published in the journal Translational Psychiatry found brain scans performed on a 39- year-old former NFL player who had sustained 22 concussions revealed that the biomarker AV1451 bound to the parts of his brain in the same way as in people diagnosed with CTE posthumously. The findings, by doctors at the Icahn School of Medicine at Mount Sinai, suggest the biomarker could be used to flag individuals at risk for CTE in the future. - Icahn School of Medicine at Mount Sinai Learn more: http://www.newsmax.com/Health/Brain-Health/cte-dementia-nfl- concussion/2016/09/28/id/750676/

Health Care Business – September 28 Icahn School of Medicine at Mount Sinai hosts Fifth Annual SINAInnovations conference and First SINAIMedMaker Challenge A new health care technology competition is among the events planned for the fifth annual SINAInnovations conference, which will be held next month at the Icahn School of Medicine at Mount Sinai. This year's SINAInnovations, with the theme of "Therapeutic Discovery," will be held October 25- 26, and will include keynote addresses, panel discussions, and breakout sessions featuring international thought leaders across the range of relevant fields. "As we embark on our fifth year of SINAInnovations, Mount Sinai remains deeply committed to innovation and discovery. This conference brings together great minds and thought leaders in both medicine and technology, with the ultimate goal of improving human health globally and locally," said Scott L. Friedman, MD, dean for Therapeutic Discovery at the Icahn School of Medicine at Mount Sinai and director of the conference. - Scott Friedman, MD, Irene and Dr. Arthur Fishberg Professor of Medicine, Liver Disease, Pharmacology and Systems Therapeutics, Dean, Therapeutic Discovery, Icahn School of Medicine at Mount Sinai, Chief, Division of Liver Diseases, The Mount Sinai Hospital Learn more: https://www.dotmed.com/news/story/33201

MedScape – September 28 Gene Variant May Predict Antidepressant Response Researchers have identified a genetic variant associated with response to bupropion in patients with major depressive disorder (MDD). Using data from customers of genetic testing company 23andMe, Inc, they found that for individuals with the genetic variant rs1908557, the odds were higher that treatment with bupropion would be ineffective. They also identified several "gene sets" associated with long-term depression, circadian rhythm, and the vascular endothelial growth factor pathway that were enriched in the bupropion response analysis. "I think this is a good paper," Scott Russo, PhD, associate professor of neuroscience, Icahn School of Medicine at Mount Sinai, noted in an interview with Medscape Medical News. "What's interesting about using 23andMe customers is that I think it will include populations of people that typically wouldn't take part in a research study, and so that data – kind of like Facebook mining – could reach a group of potential participants that are underrepresented in traditional research settings," explained Dr Russo, who was not involved in the study. "For genomics and genetics and understanding linkages to particular diseases or treatment responses, that would be a huge benefit in enriching for patients who you have low power for in your more traditional studies.” -Scott Russo, PhD, Associate Professor, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/869394

New York 1 News (Time Warner Cable) – September 28 Type One Diabetes is on the Rise among Young People – Erin Billups Sofia is part of an unexplainable growth in children and teens diagnosed with type one diabetes. Her endocrinologist Robert Rapaport, MD, professor of pediatrics and endocrinology and chief of Division of Pediatric Endocrinology and Diabetes at Icahn School of Medicine at Mount Sinai, says the symptoms are often overlooked. "What we do sometimes see a child who goes to the emergency room because of some vomiting for example, or weight loss, and they do not think of diabetes as a possible cause for that and then they go back, and back and then they present in severe form," Dr. Rapaport said. -Robert Rapaport, MD, Professor, Pediatrics, Endocrinology, Chief, Division of Pediatric Endocrinology, Icahn School of Medicine at Mount Sinai Learn more: http://www.ny1.com/nyc/all-boroughs/health-and-medicine/2016/09/28/type-one-diabetes- is-on-the-rise-among-young-people.html

EveryDay Health – September 8 6 Ways Weight Loss Can Help Control Diabetes – Marie Suszynski Losing 5 to 10 percent of your body weight may help you better control your type 2 diabetes. One way is by helping lower your blood pressure and cholesterol levels. High blood pressure and cholesterol levels are common complications of type 2 diabetes. When you have both high blood pressure and high blood sugar, it can lower HDL (“good” cholesterol) levels while raising LDL (“bad” cholesterol) and triglycerides, another blood fat. Excess weight adds to the problem. “Obesity is a known risk factor for high cholesterol, high blood pressure, and coronary artery disease,” says Deena Adimoolam, MD, assistant professor of endocrinology at the Icahn School of Medicine at Mount Sinai. But losing weight can lower your risk. In a study of 401 people who were overweight or obese, those who lost 5 to 10 percent of their body weight significantly lowered their total cholesterol, triglycerides, and LDL. Those who lost more than 10 percent saw even more improvement, according to the study, published in September 2016 in the journal Translational Behavioral Medicine. High-risk patients also significantly lowered their fasting glucose levels. Deena Adimoolam, MD, Assistant Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://www.everydayhealth.com/hs/diabetes-guide-managing-blood-sugar/how-losing- weight-helps/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

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In the News September 28, 2016

The New York Times – September 27 Researchers Make Progress Toward Identifying CTE in the Living — Ken Belson One of the frustrations of researchers who study chronic traumatic encephalopathy, the degenerative brain disease linked to repeated head hits, is that it can be detected only in autopsies, and not in the living. A study published in the journal Translational Psychiatry focused on a 39-year-old former N.F.L. player who had sustained 22 concussions. Doctors at the Icahn School of Medicine at Mount Sinai in New York said PET scans revealed that the biomarker AV1451 bound to the parts of the player’s brain in the same way as in people diagnosed with C.T.E. posthumously - Samuel Gandy, MD, PhD, Professor, Neurology, Psychiatry, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Center for Cognitive Health, Associate Director, Mount Sinai Alzheimer's Disease Research Center, Director, NFL Neurological Care Program at The Mount Sinai Hospital Learn more: http://www.nytimes.com/2016/09/27/sports/football/cte-concussions-diagnose-in-living.html? rref=collection%2Fsectioncollection%2Fhealth&action=click&contentCollection=health®ion=stream&module=stream_unit&version=latest&contentPlacement=1&pgtype=sectionfront&_r=0&mtrref=undefined Additional Coverage: Healthline: http://www.healthline.com/health-news/traumatic-brain-injuries-in-living-patients Medpage Today: http://www.medpagetoday.com/Neurology/HeadTrauma/60475 Science Daily: https://www.sciencedaily.com/releases/2016/09/160927114413.htm

Healthline – September 26 Fungi Has Its Own Role in Crohn’s Disease — Kristen Fischer Recent research on Crohn’s disease has focused a lot on bacteria, but a new study has concluded that fungus is a factor in developing the inflammatory bowel disease. Jean-Frédéric Colombel, MD, director of the Susan and Leonard Feinstein IBD Clinical Center at Mount Sinai, participated in the research. Although fungi have been known to be in our bodies, this study sheds more light on the role it can play. “Maybe in the future if we want to treat patients with Crohn’s disease … we should think about not only their bacteria but also the fungi,” he told Healthline. - Jean-Frédéric Colombel, MD, Professor, Medicine Gastroenterology, Icahn School of Medicine at Mount Sinai, Director, Susan and Leonard Feinstein IBD Clinical Center at Mount Sinai Learn more: http://www.healthline.com/health-news/fungi-role-in-crohns-disease#3

The Economic Times – September 27 Unknown Exposure to Second-Hand Smoke May Cause Early Death US researchers have identified a new biomarker which revealed that known and unknown exposure to second-hand smoke may lead to an increased risk of mortality in non-smokers. Serum cotinine — a metabolite of nicotine —was found to have associations to overall and cause-specific mortality in non-smokers. “Using cotinine level to measure exposure to second-hand smoke has important public health implications, because increasing the scope of smoke-free environments would likely decrease cotinine levels in the general population and ultimately death,” said Emanuela Taioli, MD, PhD, Director of the Institute for Translational Epidemiology at The Mount Sinai Hospital. “The study found that non-smokers are exposed to second-hand smoke without even realizing it,” said Raja Flores, MD, chair of thoracic surgery at the Icahn School of Medicine at Mount Sinai. - Emanuela Taioli, MD, PhD, Senior Faculty, Population Health Science and Policy, Thoracic Surgery, Icahn School of Medicine at Mount Sinai, Director, Institute for Translation Epidemiology at Mount Sinai - Raja Flores, MD, Steven and Ann Ames Professorship in Thoracic Surgery, Icahn School of Medicine at Mount Sinai, System Chair, Thoracic Surgery, Mount Sinai Health System Learn more: http://economictimes.indiatimes.com/magazines/panache/beware-unknown-exposure-to-second-hand-smoke-may-cause-early-death/articleshow/54563939.cms Additional Coverage: The India Tribune: http://www.tribuneindia.com/news/health/story/301548.html India Express: http://indianexpress.com/article/lifestyle/health/unknown-exposure-to-second-hand-smoke-may-cause-early-death-3053221/

Genetic Engineering and Biotechnology News – September 27 Icahn Med School Appoints Head of Institute for Next Generation Healthcare The Icahn School of Medicine at Mount Sinai appointed Joel Dudley, PhD, as the first director of its Institute for Next Generation Healthcare. “Dr. Dudley will help lay a foundation for research and technology development programs that will accelerate the transition to next-generation health care and transform medicine in the coming decades,” said Dennis S. Charney, MD, Anne and Joel Ehrenkranz Dean of the Icahn School of Medicine at Mount Sinai. “Our vision is to realize exponential improvements in patient outcomes and to improve the care experience for both providers and patients through human-centered application of advanced technologies,” said Dr. Dudley. - Dennis S. Charney, MD, Anne and Joel Ehrenkranz Dean, Icahn School of Medicine at Mount Sinai, President for Academic Affairs, Mount Sinai Health System - Joel Dudley, PhD, Associate Professor, Medicine, Genetics and Genomic Sciences, Population Health Science and Policy, Director, Biomedical Informatics, Icahn School of Medicine at Mount Sinai, Director, Institute for Next Generation Healthcare Learn more: http://www.genengnews.com/gen-news-highlights/icahn-med-school-appoints-head-of-institute-for-next-generation-healthcare/81253254/

InAVate – September 27 Ahead Of The Game: AR and VR in Neurosurgery — Charlotte Ashley Joshua Bederson, MD, chairman of neurosurgery for Mount Sinai Health System, may have recently hit the headlines for being the first in the world to use an AR image injection system called CaptiView in surgery, but the neurosurgeon has long been involved with bringing technology innovation to the operating room. Mount Sinai’s neurosurgery department was the first in the country to acquire a NeuroTouch VR simulator. The recent surge of interest in AR and VR has caused the medical world to take notice. “There’s so much interest in virtual reality now that patients and doctors are all clamoring to do it,” says Dr. Bederson. - Joshua Bederson, MD, Professor, Neurosurgery, Icahn School of Medicine at Mount Sinai, System Chair, Neurosurgery, Mount Sinai Health System Learn more: http://www.inavateonthenet.net/features/article/ahead-of-the-game-vr-and-ar-in-neurosurgery

WCBS 2 – September 27 New Drug Xiidra Helps People Battling Dry Eyes — Max Gomez A new drug may help people suffering from dry eyes. CBS2’s Dr. Max Gomez reported that dry eyes are the number one reason people go see an eye care professional. Dry eyes can lead to fluctuating vision, affecting everything from driving to reading. “It’s an anti-inflammatory, so in that sense it’s in the same group, but it has a total different mechanism of action. It prevents the white blood cells from getting to the area of inflammation, which is the white part of the eye,” said Penny Asbell, MD, a professor of ophthalmology at the Icahn School of Medicine at Mount Sinai. - Penny Asbell, MD, Professor, Ophthalmology, Icahn School of Medicine at Mount Sinai, Director, Cornea Service, Refractive Surgery, The Mount Sinai Hospital Learn more: http://newyork.cbslocal.com/2016/09/27/xiidra-eye-drug/

US News and World Report – September 21 Has Losing Weight Left You Feeling Exposed? — Michael O. Schroeder Weight-loss success stories tend to highlight the significant impact losing excess pounds can have on a person’s physical health and outlook on life. “We see a substantial improvement in quality of life, including measures of psychological health,” says Paul Thodiyil, MD, director of the Bariatric Surgery Program at Mount Sinai Beth Israel. But he also notes that some bariatric patients find unexpected interpersonal issues can arise as the result of dramatic weight loss. "Sometimes this may result in difficulties in their [pre-existing] personal relationships," he says. As part of regular ongoing follow-up care with a patient's surgical team, Dr. Thodiyil says it's important to discuss such concerns, and that providers try to be proactive in alerting patients to potential issues that may arise. - Paul Thodiyil, MD, Assistant Professor, Surgery, Icahn School of Mount Sinai, Director, Bariatric Surgery Program, Mount Sinai Beth Israel Learn more: http://health.usnews.com/wellness/articles/2016-09-21/has-losing-weight-left-you-feeling-exposed

Reader’s Digest – September 27 10 Little Ways to Boost Your Health This Fall — Alyssa Jung Plenty of autumn veggies can add a healthy bump to your diet, like fiber-filled beets, vitamin C-packed hearty Brussels sprouts, and potassium-rich sweet potatoes. “Fall is a great to time to get all these new vegetables so you can be smart about the way you change seasons,” says Shanna Levine, MD, a primary care physician and clinical instructor of medicine at the Icahn School of Medicine at Mount Sinai. She also stresses the importance of getting a flu shot. - Shanna Levine, MD, Instructor, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.rd.com/health/wellness/healthy-fall-tips/

The New York Times – September 26 Chris Bosh’s Desire to Play Leaves Heat at an Ethical Crossroads — Scott Cacciola In one of the strangest and most ethically challenging standoffs in sports history, Chris Bosh and the Miami Heat are locked in a dispute over whether he should be deemed medically fit to play after dealing with serious health problems. People with blood clots typically take blood-thinning medication, which is probably one of the most daunting hurdles for Bosh. Athletes who are on blood thinners are advised to avoid contact sports because of an increased chance of internal bleeding and other complications. Even an elbow to the ribs could cause significant damage, said David Forsh, MD, an assistant professor of orthopaedics at the Icahn School of Medicine at Mount Sinai in Manhattan. “There are a lot of risks,” he said. - David Forsh, MD, Assistant Professor, Orthopaedics, Icahn School of Medicine at Mount Sinai Learn more: http://www.nytimes.com/2016/09/27/sports/basketball/chris-bosh-miami-heat-blood-clots.html?_r=0

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Werle, Laura Subject: Mount Sinai In the News - September 27, 2016 Date: Tuesday, September 27, 2016 2:21:57 PM Attachments: ATT00002.txt

In the News September 27, 2016

Healio Dermatology – September 26 Skin Phenotype of Atopic Dermatitis Identified in Infants Researchers at the Icahn School of Medicine at Mount Sinai and Northwestern University’s Feinberg School of Medicine have identified the skin phenotype of atopic dermatitis in infants, according to a press release. The researchers, Emma Guttman-Yassky, MD, PhD, a professor of dermatology at the Icahn School of Medicine at Mount Sinai, and Amy S. Paller, MD, chair of the department of dermatology at Northwestern, determined that the nonlesional skin of young children with early eczema is already highly abnormal with significant immune activation. - Emma Guttman-Yassky, MD, PhD, Professor, Dermatology, Medicine, Clinical Immunology, Icahn School of Medicine at Mount Sinai, Director, Center for Excellence in Eczema, Occupational/Contact Dermatitis Clinic Learn more: http://www.healio.com/dermatology/pediatric-dermatology/news/online/%7B5d966a64- ad88-4d5b-ac7d-86e30e5776a8%7D/skin-phenotype-of-atopic-dermatitis-identified-in-infants Additional Coverage: eDermatology News: http://www.edermatologynews.com/specialty-focus/atopic-dermatitis/single- article-page/new-onset-pediatric-ad-phenotype-differs-from-adult- ad/d7ec55b081809862dcb693e6529af7cc.html

STAT News – September 27 Concussion Researchers Spark Hope With A New Tool To Diagnose Brain Damage — Eric Boodman Researchers at the Icahn School of Medicine at Mount Sinai report they have developed a potential method to diagnose CTE while patients are still alive. Until now, diagnosis was only possible after death. The stakes for this science are high. Neurologists think that the brain damage associated with CTE is linked to a protein called tau, which is an essential part of normal, healthy neurons. “The structure is maintained by an internal skeleton of the nerve cell, and that skeleton is composed of tau,” explained Sam Gandy, MD, PhD, director of the Center for Cognitive Health at The Mount Sinai Hospital, who led the new study. - Samuel Gandy, MD, PhD, Professor, Neurology, Psychiatry, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Center for Cognitive Health, Associate Director, Mount Sinai Alzheimer's Disease Research Center, Director, NFL Neurological Care Program at The Mount Sinai Hospital Learn more: https://www.statnews.com/2016/09/27/cte-diagnosis-concussion/

Medscape – September 26 Drug-Eluting Stents Can't Outmuscle Harmful Effects of Coronary Calcification in Women: Study — Patrice Wendling A pooled analysis shows moderate or severe coronary artery calcification (CAC) dramatically increases the risk for hard adverse events in women undergoing PCI even with newer drug-eluting stents (DES). "This adverse effect was consistent across all the subsets and even with the new-generation DES, which have overcome a lot of the bad outcomes," said senior investigator Roxana Mehran, MD, a professor of cardiology at the Icahn School of Medicine at Mount Sinai. The investigators, led by Gennaro Giustino, MD, a postdoctoral fellow in interventional cardiology at the Zena and Michael A. Wiener Cardiovascular Institute at Icahn School of Medicine at Mount Sinai, observe that even with meticulous lesion preparation, optimal stent expansion and strut apposition are not always achieved. - Roxana Mehran, MD, Professor, Medicine, Cardiology, Population Science and Health Policy, Director, Interventional Cardiovascular Research and Clinical Trials, Icahn School of Medicine at Mount Sinai - Gennaro Giustino, MD, Postdoctoral Clinical Research Fellow, Interventional Cardiology, Zena and Michael A. Wiener Cardiovascular Institute at the Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/869239

TCT MD – September 26 Large Swings in Visit-to-Visit Systolic Blood Pressure Linked With Increased Risk of Death — Michael O’Riordan Large swings in systolic blood pressure over a series of physician visits are a sign that patients may face higher risks of all-cause mortality, coronary heart disease, stroke, and end-stage renal disease, according to a large study of US veterans. In an editorial accompanying the study, Lawrence Krakoff, MD, a professor of cardiology at the Icahn School of Medicine at Mount Sinai, and Robert Phillips, MD, from Weill Cornell Medical College, state that the size of the present study “dwarfs previous surveys and provides robust support for the importance of systolic blood pressure in predicting risk of future mortality and cardiovascular and renal disease.” - Lawrence Krakoff, MD, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.tctmd.com/show.aspx?id=136246

Science Daily – September 26 Unknown Exposure to Second-Hand Smoke Associated With Increased Mortality A new biomarker has identified known and unknown exposure to second-hand smoke and confirmed a strong association to increased mortality in non-smokers, according to a new study. "A crucial finding of this study is that non-smokers are exposed to second-hand smoke without even realizing it," said Raja Flores, MD, chair of thoracic surgery at the Icahn School of Medicine at Mount Sinai. "Using cotinine level to measure exposure to second-hand smoke has important public health implications, because increasing the scope of smoke-free environments would likely decrease cotinine levels in the general population and ultimately death," said Emanuela Taioli, MD, PhD, Director of the Institute for Translational Epidemiology at The Mount Sinai Hospital. - Raja Flores, MD, Steven and Ann Ames Professorship in Thoracic Surgery, Icahn School of Medicine at Mount Sinai, System Chair, Thoracic Surgery, Mount Sinai Health System - Emanuela Taioli, MD, PhD, Senior Faculty, Population Health Science and Policy, Thoracic Surgery, Icahn School of Medicine at Mount Sinai, Director, Institute for Translation Epidemiology at Mount Sinai Learn more: https://www.sciencedaily.com/releases/2016/09/160926105747.htm

Medscape – September 26 Newborn Screening for SCID Making Gains Globally — Marcia Frellick The screening of newborns for severe combined immunodeficiency disease (SCID) is now required in 41 states, and several organizations are pushing for the remaining states to make it mandatory. But there is some reluctance. "The test costs $3 or so per infant, even with no repeat tests, and the states have to pay for it," said Charlotte Cunningham-Rundles, MD, the David S. Gottesman Professor of Immunology at the Icahn School of Medicine at Mount Sinai. - Charlotte Cunningham-Rundles, MD, David S. Gottesman Professor of Immunology, Professor, Medicine, Pediatrics, Icahn School of Medicine at Mount Sinai, Director, Immunodeficiency Clinical at Mount Sinai, Program Director, Allergy Immunology Fellowship Program, The Mount Sinai Hospital Learn more: http://www.medscape.com/viewarticle/869263

HNGN – September 27 Milestone In War Against Prostate Cancer — Grace Moleno Prostate cancer is the second most common cause of cancer in men. The diagnosis and treatment for this type of cancer often come late because there may be no signs that one has it for years. Studies reveal that African-American men, especially those with a family history of this disease, are more prone to prostate cancer. "They do have 1.5 times greater risk of having prostate cancer and twice the mortality of they get it," according to Ash Tewari, MD, chair of urology at the Mount Sinai Health System. He stresses the importance of exercise, before and after any treatment. - Ash Tewari, MBBS, MCh, Professor, Urology, Icahn School of Medicine at Mount Sinai, System Chair, Urology, Mount Sinai Health System Learn more: http://www.hngn.com/articles/208474/20160927/advances-on-men-on-prostate-cancer.htm

Family Circle – September 20 Mammograms Multitask A thorough breast exam could tell you more than you think about possible unrest in your chest. Recent research found that if the exam reveals calcium in the arteries of the breast, that might signal a buildup of plaque in the arteries of your heart. “Mammograms have been shown to save lives from breast cancers, says lead author Laurie Margolies, MD, associate professor of radiology at Icahn School of Medicine at Mount Sinai. “ The same test may save lives from even deadlier cardiovascular disease.” - Laurie Margolies, MD, Associate Professor, Radiology, Icahn School of Medicine at Mount Sinai, Director of Breast Imaging, Dubin Breast Center of The Mount Sinai Hospital Learn more: no web link available.

HealthDay News – September 26 Is Morning Sickness a Good Thing? — Dennis Thompson While morning sickness may make you miserable in the early months of your pregnancy, it can signal that your baby is healthy and normal, new research shows. Morning sickness most often is chalked up to changing hormone levels in newly pregnant women, particularly levels of the "pregnancy hormone," known as human chorionic gonadotropin, explained Noel Strong, MD, an assistant professor of obstetrics, gynecology and reproductive science at the Icahn School of Medicine at Mount Sinai. "With higher levels of pregnancy hormones, women are more likely to be symptomatic and have symptoms like nausea and vomiting," Dr. Strong said. "We often will see these symptoms more commonly in women carrying twins, where the hormone levels are higher." - Noel Strong, MD, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: https://consumer.healthday.com/sexual-health-information-32/miscarriage-news- 478/morning-sickness-a-good-sign-715170.html Additional Coverage: Tech Times: http://www.techtimes.com/articles/179544/20160926/morning-sickness-during-pregnancy- nausea-and-vomiting-linked-to-lower-miscarriage-risk.htm

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Slotnick, David Subject: Mount Sinai In The News - September 26, 2016 Date: Monday, September 26, 2016 1:15:06 PM Attachments: ATT00002.txt

In the News September 26, 2016

The Wall Street Journal – September 25 Physicians and Physicists Join Forces to Fight Pancreatic Cancer — Ron Winslow A team of physicians and physicists, and other scientists with differing backgrounds are engaged in a novel effort to solve the riddle of pancreatic cancer, one of medicine’s most lethal malignancies. In an emerging transformation of scientific research known as convergence, experts from disparate fields pool their skills and knowledge to find answers to complex medical problems. The pancreatic-cancer convergence team features three physicians, including a leader in the burgeoning field of immuno- oncology, and three physicists, including a computational biologist. “This is the changing face of cancer research,” says Benjamin Greenbaum, PhD, a quantitative biologist and Assistant Professor at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai in New York, also a convergence team member. “It’s no longer a guy in a white coat trying to see how many tumor cells die when you pour a chemical onto a petri dish,” he says. - Benjamin Greenbaum, PhD, Assistant Professor, The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai Learn more: http://www.wsj.com/articles/physicians-and-physicists-join-forces-to-fight-pancreatic- cancer-1474855741

The Wall Street Journal – September 25 The Revolution in EMS Care — Laura Landro In what could amount to a sea change for many EMS workers, health-care policy makers are looking at having so-called community paramedicine teams provide preventive care—and even make regularly scheduled house calls. There are big hurdles, including payment policies which generally reimburse EMS providers only when they transport patients to a hospital. Many EMS services are financially strapped due to the hospital-transport-only reimbursement policy, says Kevin Munjal, MD, MPH, director of prehospital care at the Mount Sinai Health System. By creating a system that reimburses EMS professionals to do things like treat patients at home, move them to other health-care providers and check on them after they leave the hospital, “we could unleash innovative new models of care that meet unmet needs, while making emergency response more reliable,” says Dr. Munjal, who is leading a nationwide EMS innovation project. Otherwise, he warns, “many would argue that EMS’s ability to be there in emergencies is under threat.” - Kevin Munjal, MD, MPH, Assistant Professor, Emergency Medicine, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai Learn more: http://www.wsj.com/articles/the-revolution-in-ems-care-1474855802

The New York Times – September 24 The Doctor Is In. In Your House, That Is. — John F. Wasik There is growing evidence that comprehensive home medical care could be a viable alternative to the attendant woes and soaring expenses of institutional health services. It will take some important legislative changes before focused, less intrusive care in a dignified, comfortable setting can become more widely available. However, given the overall popularity of Medicare, getting a new home medical care benefit through Congress looks more promising. Linda V. DeCherrie, MD, Associate Professor of Geriatrics and Palliative Medicine at the Icahn School of Medicine at Mount Sinai, who runs one of the largest academic house call programs in the country, received a $9.6 million Medicare innovation award to study the expansion of home care “to include hospital level care at home and what it means for patients.” Dr. DeCherrie, who supervises two programs at Mount Sinai that treat more than 1,500 patients, says comprehensive home-based health care “has the potential to provide solutions for many problems,” suggesting that seeing patients in their natural environment may offer improved care. “It can be quite an ordeal to see a doctor in a hospital if you are a frail older adult,” Dr. DeCherrie said. “Patients are much happier not to have to go through that. In a home, you can get a better picture of what’s going on.” - Linda DeCherrie, MD, Associate Professor, Medicine, Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Visiting Doctors Program, Program Director, Primary Care Internal Medicine Residency Program, The Mount Sinai Hospital Learn more: http://www.nytimes.com/2016/09/24/your-money/the-doctor-is-in-in-your-house-that- is.html Additional Coverage: The Bulletin: http://www.bendbulletin.com/business/4687222-151/the-doctor-is-in-your-house-that-is? referrer=bullet3

MedicalResearch.com – September 25 Early Immune Intervention May Prevent Atopic March of Eczema and Allergies MedicalResearch.com interviewed Emma Guttman-Yassky, MD, PhD, Professor of Dermatology and Clinical Immunology and Director of the Center for Excellence in Eczema at the Icahn School of Medicine at Mount Sinai, about her new study on early immune intervention for eczema. “The important findings may suggest the need for early immune intervention at a young age, not only to treat the eczema but perhaps also to prevent other allergic diseases (such as asthma, food allergies, seasonal allergies which usually follow the development of eczema, also known as the atopic march,” said Dr. Guttman-Yassky, whose research on atopic dermatitis focuses on the mechanism of the underlying disease and promotes development of targeted therapeutics. Her past research has identified biomarkers for current treatments for AD. - Emma Guttman-Yassky, MD, PhD, Professor, Dermatology, Medicine, Clinical Immunology, Icahn School of Medicine at Mount Sinai, Director, Center for Excellence in Eczema, Occupational/Contact Dermatitis Clinic Learn more: http://medicalresearch.com/allergies/early-immune-intervention-may-prevent-atopic- march-eczema-allergies/28328/ Additional Coverage: ScienceDaily: https://www.sciencedaily.com/releases/2016/09/160923083802.htm

GenomeWeb – September 26 Researchers Hope PharmCAT Tool Will Help Improve Clinical Implementation of Pharmacogenomics — Julia Karow A consortium of researchers has developed a bioinformatic software tool for the annotation and interpretation of pharmacogenetic variants that it hopes will improve the implementation of pharmacogenomics in the clinic. The software, called Pharmacogenomics Clinical Annotation Tool (PharmCAT), takes PGx variants from sequencing and genotyping data of certain genes, interprets the variant alleles, infers haplotype pairs and star alleles, and generates guideline-based reports that can help physicians make drug prescription decisions. The Genetic Testing Laboratory at the Icahn School of Medicine at Mount Sinai is one of the labs interested in testing PharmCAT. "It's something we would consider and test for inclusion in our informatics workflow," along with in-house developed tools, said Stuart Scott, Assistant Professor of Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai, and director of Mount Sinai's Molecular Genetics Laboratory as well as its Cytogenetics and Cytogenomics Laboratory. Scott has also been involved in the development of PharmCAT. - Stuart Scott, PhD, Assistant Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai Learn more: https://www.genomeweb.com/molecular-diagnostics/researchers-hope-pharmcat-tool-will- help-improve-clinical-implementation

Orthopedics This Week – September 21 Mount Sinai Beth Israel: Gold Seal Of Approval — Elizabeth Hofheinz The hip and knee program at Mount Sinai Beth Israel in New York City is shining these days, having just earned The Joint Commission’s Gold Seal of Approval for Advanced Certification for Total Hip and Total Knee Replacement. This is the only hospital in New York City to receive this certification for an orthopedic program. “This entire process was a team effort, and our success during this review is a reflection of the outstanding staff that we have here in the orthopedics department,” said Peter McCann, MD, chair of the department of orthopaedic surgery at Mount Sinai Beth Israel. - Peter McCann, MD, Professor, Orthopaedics, Icahn School of Medicine at Mount Sinai, Chair, Department of Orthopaedic Surgery, Mount Sinai Beth Israel Learn more: https://ryortho.com/breaking/mount-sinai-beth-israel-gold-seal-of-approval/

MD/alert – September 22 Sweet-liking and High Craving for Alcohol Tied to Better Response to Naltrexone — Marilynn Larkin Alcohol-dependent individuals who crave alcohol and like sweets are more likely to respond to treatment with naltrexone, researchers say. Researchers recruited 80 actively drinking patients for a 12- week trial. After the initial screening, participants were encouraged, but not required, to be sober for three days before randomization. As reported in JAMA Psychiatry, online September 14, 40 participants were randomized to 50 mg daily of oral naltrexone and 40 received placebo. All were given weekly or biweekly counseling. Eleven participants in each group had the sweet-liking (SL) phenotype and 29 in each group were sweet-disliking (SDL). While the study is "promising in understanding a potential moderating variable which can help in determining potential positive responses to naltrexone therapy," it does not show causality, according to Paul Rinaldi, PhD, director of the Addiction Institute of New York at the Mount Sinai Health System. "The study was small and the results, while promising, require further larger replicative research to confirm the findings," he added. - Paul Rinaldi, PhD, Director, Addiction Institute of New York, Mount Sinai St. Luke’s and Mount Sinai West Learn more: http://www.mdalert.com/news/article/sweet-liking-and-high-craving-for-alcohol-tied-to- better-response-to-naltrexone

WABC – September 25 New Advances Helping Men in the Fight Against Prostate Cancer — Rob Nelson September is prostate cancer awareness month, a time to encourage men to take control of their health and go to the doctor. Ken Sneider got his prostate cancer diagnosis at age 59, the same illness that took the life of his grandfather. After more tests and a second opinion, that next step ultimately became surgery, and that's when Ken turned to Ash Tewari, MD the chair of urology at the Mount Sinai Health System. A new option for patients is robotic surgery, which is Dr. Tewari's specialty. It's been around for about 15 years and it minimizes bleeding, is less invasive and allows for better visual magnification of the cancer. "[With those t]hree things combined, prostate cancer surgery becomes easier, so that is the reason why most of the operations are done now with the robot," said Dr. Tewari. - Ash Tewari, MBBS, MCh, Professor, Urology, Icahn School of Medicine at Mount Sinai, System Chair, Urology, Mount Sinai Health System Learn more: http://abc7ny.com/1525941/

New York Daily News – September 23 Doc ’n’ Roll — These OB-GYNs Are Rocking to End Women’s Cancers — Nicole Lyn Pesce This New York OB-GYN is drumming up a cure for women’s cancers. Nimesh P. Nagarsheth, MD, associate professor of obstetrics, gynecology and reproductive science and associate director of gynecologic oncology at the Icahn School of Medicine at Mount Sinai, is one of six gyno-mite surgeons who make up No Evidence of Disease, a charity alt-rock band that’s spent the past eight years working on cancer’s swan song. They played the Cutting Room in Midtown East on Saturday to raise money for the Foundation for Women’s Cancer. “It’s just been a great whirlwind. Such a dream come true for all of us,” says Dr. Nagarsheth, who notes it’s actually very common for physicians to moonlight as rockstars. “Many of us have mastered some instrument, because we work with our hands every day. Drumming has helped me to become a better surgeon.” - Nimesh Nagarsheth, MD, Associate Professor, Obstetrics, Gynecology and Reproductive Science, Associate Director, Gynecologic Oncology, Icahn School of Medicine at Mount Sinai Learn more: http://www.nydailynews.com/life-style/health/doc-n-roll-ob-gyns-rocking-women- cancers-article-1.2803635

MedicalResearch.com – September 22 Decision-Making in Laryngology: Both Sides of the Story MedeicalResearch.com interviewed Mark Courey, MD, director of the Eugen Grabscheid Voice Center at The Mount Sinai Hospital, to discuss voice disorders. “The most common causes of voice disorders are inefficient voice use patterns,” said Dr. Courey. “This is when patients try to use their voice in a way that is not well suited for their physical stature or training.” - Mark Courey, MD, Senior Faculty, Otolaryngology, Icahn School of Medicine at Mount Sinai, Director, Eugen Grabscheid Voice Center, The Mount Sinai Hospital, Division Chief, Laryngology, Vice Chair of Quality, Department of Otolaryngology-Head and Neck Surgery, Mount Sinai Health System Learn more: http://medicalresearch.com/author-interviews/decision-making-in-laryngology-both-sides- of-the-stor/27964/

MedicalResearch.com – September 22 ENT Surgeon Manages Middle Ear Cholesteatoma Removal In One Surgical Procedure MedicalResearch.com interviewed Eric Smouha, MD, professor of otolaryngology and director of otology and neurology at the Icahn School of Medicine at Mount Sinai. “Cholesteatoma is a specific disorder of the middle ear,” said Dr. Smouha. “Skin from the ear canal becomes trapped inside of the eardrum. It grows to form a cyst, and incites an inflammatory reaction.” - Eric Smouha, MD, Professor, Otolaryngology, Director, Otology, Neurology, Icahn School of Medicine at Mount Sinai Learn more: http://medicalresearch.com/author-interviews/ent-surgeon-manages-middle-ear- cholesteatoma-removal-in-one-surgical-procedure/28012/

MedicalResearch.com – September 22 3D Models and Immersive Virtual Reality Simulation for Complex Skull Base Surgery MedicalResearch.com interviewed Alfred Marc Calo Iloreta, Jr, MD, assistant professor of otolaryngology at the Icahn School of Medicine at Mount Sinai. “Our group has been using 3D printers for the past year or so to replicate and ‘print’ patient specific anatomy as well as their pathology,” said Dr. Iloreta. “For example, I am able to print out a patient’s skull as well as important neurovascular structures such as the carotid artery or optic nerve in addition to their specific pathology such as a tumor. Using this print I can plan how we would specifically approach and remove the tumor to maximize our ability to safely resect the tumor and minimize the morbidity of the operation itself.” - Alfred M.C. Iloreta, Jr, MD, Assistant Professor, Otolaryngology, Icahn School of Medicine at Mount Sinai Learn more: http://medicalresearch.com/author-interviews/3d-models-immersive-vr-simulation- complex-skull-base-surgery/28075/

In Style – September 26 Three Ways to Reduce Breast Cancer Risk Elisa Port, MD, co-director of the Dubin Breast Center, offered three ways to reduce breast cancer risk: managing body weight, reducing alcohol consumption, and avoiding excess hormones. “Treating menopausal symptoms like hot flashes with hormone replacement therapy can stimulate the growth of cancer cells,” Dr. Port said. - Elisa Port, MD, FACS, Associate Professor, Surgery, Icahn School of Medicine at Mount Sinai, Chief, Breast Surgery, Co-Director, Dubin Breast Center, The Mount Sinai Hospital Learn more: No web link available. If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Werle, Laura Subject: Mount Sinai In the News - September 23, 2016 Date: Friday, September 23, 2016 12:36:14 PM Attachments: ATT00002.txt

In the News September 23, 2016

Modern Healthcare – September 22 Peterson Center Launches Initiative to Improve Primary Care — Shelby Livingston The Peterson Center on Healthcare is launching an initiative to improve quality of care, patient satisfaction and reduce costs at three primary care practices across the country, including Mount Sinai Doctors Faculty Practice at West 147th Street. “The team surfaced its own goals and learned how to apply improvement methodologies to improve how they work,” Niyum Gandhi, chief population health officer for the Mount Sinai Health System, said in the statement announcing the initiative. “We are already seeing benefits, including higher quality outcomes, more time spent between clinicians and patients, and more streamlined administration.” - Niyum Gandhi, Chief Population Health Officer, Mount Sinai Health System Learn more: http://www.modernhealthcare.com/article/20160922/NEWS/160929957 Additional Coverage: Politico Pro New York Health Care: http://www.politico.com/states/new-york/tipsheets/politico-new- york-health-care/2016/09/ags-sue-maker-of-suboxone-for-anti-competitive-business-practices-005214

Crain’s New York – September 23 Mount Sinai's Harlem Clinic Transforms Primary Care — Jonathan LaMantia The Peterson Center on Healthcare, a Manhattan-based foundation, has implemented primary-care strategies to boost performance at three U.S. clinics, including Mount Sinai Doctors Faculty Practice at West 147th Street. The nonprofit organization, which is devoted to improving quality and lowering costs in U.S. health care, said Thursday it is replicating approaches in place at certain "high-value" practices around the country, which Peterson said deliver high-quality care at an affordable price. Recent changes freed up 10 hours a week in staff time, said Prabhjot Singh, MD, PhD, chair of the department of health system design and global health at the Icahn School of Medicine at Mount Sinai. "It's these small changes that have cascading effects," he said. Mount Sinai plans to emulate the Peterson Center model at other primary care practices. - Prabhjot Singh, MD, PhD, Senior Faculty, Medicine, General Internal Medicine, Director, Arnhold Global Health Institute, Chair, Department of Health System Design and Global Health, Icahn School of Medicine at Mount Sinai Learn more: http://www.crainsnewyork.com/article/20160923/PULSE/160929947/how-new-yorks- independent-docs-are-getting-squeezed-financially (subscription required)

CBS News – September 22 Report: Scientist the First To Edit Genes of Healthy Human Embryos — Ashley Welch A Swedish scientist is believed to be the first in the world to attempt to edit DNA in healthy human embryos, according to an exclusive report from NPR. The practice is controversial and has been criticized throughout the scientific community over safety and ethical concerns. Last year, Chinese scientists tried to edit DNA using “non-viable” human embryos. “We don’t really understand enough of the genome to be making these types of changes,” Eric Schadt, PhD, chair of the department of genetics and genomics at the Icahn School of Medicine at Mount Sinai, told CBS when the news from China broke. “We’re making fundamental changes to the gene pool and we don’t necessarily understand how we adapt to different environmental changes and changes we may make today may not be advantageous 100 years from now.” - Eric Schadt, PhD, Jean C. and James W. Crystal Professor of Genomics, Chair, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Founding Director, Icahn Institute for Genomics and Multiscale Biology Learn more: http://www.cbsnews.com/news/scientist-edits-genes-of-healthy-human-embryos-crispr- npr-report/

Eye Wire Today – September 19 Risk for Exfoliation Syndrome in Women with Pelvic Organ Prolapse New groundbreaking research involving the Icahn School of Medicine at Mount Sinai in New York City shows a possible link between women with exfoliation syndrome (XFS) and pelvic organ prolapse. “After this discovery, it’s possible that other elastic tissue conditions such as emphysema, inguinal hernia, varicose veins, and stroke may have an association with an increased incidence of exfoliation syndrome,” said Robert Ritch, MD, chief of the glaucoma service at the New York Eye and Ear Infirmary of Mount Sinai. “This study could promote researchers to examine this further, and make more potential connections between those diseases and exfoliation syndrome, to prevent vision loss for that pool of patients.” - Robert Ritch, MD, Shelley and Steven Einhorn Distinguished Chair in Ophthalmology, Chief, Glaucoma Service, Surgeon Director Emeritus, New York Eye and Ear Infirmary of Mount Sinai Learn more: http://eyewiretoday.com/2016/09/19/risk-for-exfoliation-syndrome-in-women-with-pelvic- organ-prolapse

Healio: Cardiology Today’s Intervention – September 22 CAC Linked With Higher Risk Profile In Women Undergoing PCI With DES — Jennifer Byrne Women undergoing PCI with drug-eluting stents who have moderate or severe coronary artery calcification exhibit a higher clinical risk profile compared with those without coronary artery calcification, and they continue to be at elevated risk for mid- to long-term MACE, including death. Gennaro Giustino, MD, a postdoctoral fellow in interventional cardiology at the Zena and Michael A. Wiener Cardiovascular Institute at Icahn School of Medicine at Mount Sinai, and colleagues evaluated patient-level data of 6,371 women with available coronary artery calcification (CAC) information pooled from 26 randomized trials of DES. - Gennaro Giustino, MD, Postdoctoral Clinical Research Fellow, Interventional Cardiology, Zena and Michael A. Wiener Cardiovascular Institute at the Icahn School of Medicine at Mount Sinai Learn more: http://www.healio.com/cardiac-vascular-intervention/percutaneous-coronary- intervention/news/online/%7B602feaca-5bf0-45b8-8b34-f6d4d68a4629%7D/cac-linked-with-higher-risk- profile-in-women-undergoing-pci-with-des

New York Daily News – September 21 15 Years Later, Help Is Still At The Ready For 9/11 responders — Michael Crane, MD, MPH Fifteen years after the 9/11 attacks, many thousands of people are still living with the trauma of that day and its aftermath, but help for their physical and mental needs is available to any who reach out, writes Michael Crane, MD, director of the World Trade Center Health Program Clinical Center of Excellence at Mount Sinai. There are 22,000 responders enrolled at Mount Sinai alone. We can offer them whatever treatment is necessary and screen for cancers they may be at higher risk of developing, like lung and colon cancer. There are no out-of-pocket costs for members who use health care providers approved by the WTC Health Program for medical evaluation, monitoring, and treatment. - Michael Crane, MD, MPH, Associate Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital Learn more: http://www.nydailynews.com/life-style/15-years-ready-9-11-responders-article-1.2800942

Reuters – September 22 Sweet-Liking And High Craving For Alcohol Tied To Better Response To Naltrexone — Marilynn Larkin Alcohol-dependent individuals who crave alcohol and like sweets are more likely to respond to treatment with naltrexone, researchers say. "Clinical experience tells us that some patients regard naltrexone as a great help in reducing the craving to drink alcohol while other patients experience no effect whatsoever. This study is one in a growing body of research attempting to understand the reason for such varied responses in patients,” said Paul Rinaldi, PhD, director of The Addiction Institute of New York at Mount Sinai St. Luke’s and Mount Sinai West. While the study is "promising in understanding a potential moderating variable which can help in determining potential positive responses to naltrexone therapy," it does not show causality, he said. - Paul Rinaldi, PhD, Director, Addiction Institute of New York, Mount Sinai St. Luke’s and Mount Sinai West Learn more: http://www.mdalert.com/news/article/sweet-liking-and-high-craving-for-alcohol-tied-to- better-response-to-naltrexone

Medpage Today – September 22 The INFORMS Study In a video report from the Congress of the European Committee for Treatment and Research in Multiple Sclerosis, Fred Lublin, MD, director of the Corinne Goldsmith Dickinson Center for Multiple Sclerosis at The Mount Sinai Hospital, discusses results from studies on primary progressive multiple sclerosis. - Fred Lublin, MD, FAAN, FANA, Saunders Family Professor of Neurology, Icahn School of Medicine at Mount Sinai, Director, Corinne Goldsmith Dickinson Center for Multiple Sclerosis at The Mount Sinai Hospital Learn more: http://www.medpagetoday.com/ECTRIMSVideoConferenceReporter2016/MeetingCoverage/ECTRIMS- Videos/1923

Medpage Today – September 22 New Topographical Model of Multiple Sclerosis In a video report from the Congress of the European Committee for Treatment and Research in Multiple Sclerosis, Stephen Krieger, MD, an associate professor of neurology at the Icahn School of Medicine at Mount Sinai, discuss a new model for multiple sclerosis that suggests there can be progression even in relapsing disease and relapses in progressive disease. - Stephen Krieger, MD, Associate Professor, Neurology, Icahn School of Medicine at Mount Sinai Learn more: http://www.medpagetoday.com/ECTRIMSVideoConferenceReporter2016/MeetingCoverage/ECTRIMS- Videos/1905

Politico Pro New York Health Care – September 23 Coming Soon: What A Wonderful World Gala — Dan Goldberg On Monday, the Louis Armstrong Center for Music and Medicine will host its annual "What A Wonderful World Gala" at the Highline Ballroom. Dionne Warwick is this year's musician recipient. The annual award will also be presented to a physician, a patient and a philanthropist who have served to make the world better. The awards are presented by the Louis Armstrong Center for Music and Medicine at Mount Sinai Beth Israel. - Louis Armstrong Center for Music and Medicine at Mount Sinai Beth Israel Learn more: http://www.politico.com/states/new-york/tipsheets/politico-new-york-health- care/2016/09/ags-sue-maker-of-suboxone-for-anti-competitive-business-practices-005214

LIC Post – September 22 Family Health Day to Take Place at LIC Landing Saturday — Hannah Wulkan In conjunction with a total revamp of the hospital facility, Mount Sinai Queens is hosting the Family Health Day on Saturday at LIC Landing in the hopes of advertising its new facilities, while offering healthy activities and free health checks for all ages. “We wanted to bring what we do best to the community—good healthcare. Our staff knows how to do health screenings, put on fun activities and offer giveaways; we wanted to acquaint people with our exponentially growing health services,” said Shelly Felder, senior director of marketing and communications for Mount Sinai Queens. - Shelly Felder, Senior Director, Marketing and Communications, Mount Sinai Queens Learn more: http://licpost.com/family-health-day-to-take-place-at-lic-landing-saturday

Huffington Post – September 22 Thyroid Cancer: When ‘Watchful Waiting’ Makes Sense — Ilya Likhterov, MD The most common type of thyroid cancer, called papillary thyroid cancer, traditionally has been treated with surgical removal of part or all of the thyroid gland. But, like prostate cancer, this type of cancer is rarely fatal. And so, like prostate cancer, a small tumor can be dealt with by keeping an eye on it, rather than removing the gland, writes Ilya Likhterov, MD, an assistant professor of otolaryngology at the Icahn School of Medicine at Mount Sinai. - Ilya Likhterov, MD, Assistant Professor, Otolaryngology, Icahn School of Medicine at Mount Sinai, Head and Neck Oncologic and Endocrine Surgery Team, Mount Sinai Beth Israel Learn more: http://www.huffingtonpost.com/mount-sinai-health-system/thyroid-cancer-when- watch_b_12139540.html

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Slotnick, David Subject: Mount Sinai In The News - September 22, 2016 Date: Thursday, September 22, 2016 1:42:34 PM Attachments: ATT00002.txt

In the News September 22, 2016

Crain’s Health Pulse – September 22 NY Researchers Snag NIH Grants On Children's Health — Caroline Lewis Researchers at nine New York institutions are among the national recipients of $157 million in grants from a new seven-year National Institute of Health initiative that studies the impact of environmental factors on children's health. At Mount Sinai Health System, Rosalind Wright, MD, MPH, dean of translational biomedical research at the Icahn School of Medicine at Mount Sinai, and Robert Wright, MD, MPH, chair of preventive medicine for Mount Sinai Health System, received almost $9 million for the two-year pilot to study 5,000 children to determine how exposure to a range of environmental factors in early development and childhood affects health later in life. - Rosalind Wright, MD, MPH, Professor, Pulmonary and Critical Care, Environmental Medicine and Public Health, Medicine, Pediatrics, Pulmonary, Critical Care and Sleep Medicine, Dean, Translational Biomedical Research, Icahn School of Medicine at Mount Sinai - Robert Wright, MD, MPH, Professor, Environmental Medicine and Public Health, Pediatrics, Director, Division of Environmental Health, Icahn School of Medicine at Mount Sinai, System Chair, Environmental Medicine and Public Health, Mount Sinai Health System Learn more: http://www.crainsnewyork.com/article/20160922/PULSE/160929964/nyc-startup-aims-to- make-eye-exams-easier (subscription required) Additional Coverage: Politico Pro New York Health Care: No link available.

NPR – September 21 HIV-Positive Organ Donations Are Now Underway — Meghna Chakrabarti Until 2013, organ donations in the United States could only come from people who were HIV-negative donors. The HIV Organ Policy Equity Act, signed by President Barack Obama, changed that. Sander Florman, MD, director of the Recanati/Miller Transplant Institute at The Mount Sinai Hospital, joined Meghna Chakrabarti to discuss. The Mount Sinai Hospital is one of two programs in the United States that has performed one of these transplants. “Remember there are about 100,000 people waiting for a kidney transplant in the United States and the average wait, depending on your blood type, can be anywhere from five to seven years in a place like New York,” Dr. Florman said. “Now those people will all have access to taking an HIV-positive organ, and nobody else who is HIV-negative can have access to those organs.” - Sander Florman, MD, Professor, Surgery, Icahn School of Medicine at Mount Sinai, Director, Recanati/Miller Transplantation Institute Learn more: http://www.wbur.org/hereandnow/2016/09/21/hiv-positive-organ-donations

Yahoo – September 21 New Study Shows Arthritis Drug May Combat Disfiguring Hair Loss — Jenna Birch Alopecia areata is a disfiguring autoimmune disease that causes patchy or total hair loss all over the body, including areas like the eyebrows and lashes. Emma Guttman-Yassky, MD, PhD, a professor of dermatology and clinical immunology at the Icahn School of Medicine at Mount Sinai, and her team currently have the largest pool of ongoing alopecia areata trials in the country. Just yesterday, Mount Sinai hosted an event for alopecia areata. Dr. Guttman-Yassky says she’s excited to see the wave of interest and research for the condition that “carries a 1.7 percent lifetime prevalence” and is currently “not being discussed enough” in everyday circles. “It is very devastating, and there’s a lot of emotional distress involved,” she explains. “This is one condition in which I’m pushing for more awareness.” - Emma Guttman-Yassky, MD, PhD, Professor, Dermatology, Medicine, Clinical Immunology, Icahn School of Medicine at Mount Sinai, Director, Center for Excellence in Eczema, Occupational/Contact Dermatitis Clinic Learn more: http://sports.yahoo.com/news/new-study-shows-arthritis-drug-may-combat- 134242633.html

Reuters – September 21 Just Going On Vacation May Change Gene Activity — Kathryn Doyle Researchers measured gene activity, blood markers and reported wellbeing during vacation and months afterward, and found a large and immediate “vacation effect” in all participants. For those who continued meditating, benefits were seen even 10 months later. “Vacation in a relaxing, resort-like environment takes you away from your day-to-day grind, which may be high stress in which your body is in a more defensive-like posture, with pressures to meet deadlines, dealing with angry customers, ‘battling’ with colleagues for resources to accomplish your mission or whatever,” said senior author Eric Schadt, PhD, chair of the department of genetics and genomics at the Icahn School of Medicine at Mount Sinai. - Eric Schadt, PhD, Jean C. and James W. Crystal Professor of Genomics, Chair, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Founding Director, Icahn Institute for Genomics and Multiscale Biology Learn more: http://in.reuters.com/article/us-health-aging-vacation-meditation-idINKCN11Q2RL Additional Coverage: Huffington Post: http://www.huffingtonpost.com/entry/going-on-vacation-can-actually-change-your- gene-activity_us_57e29618e4b08d73b82e9d6e

Politico Pro New York Health Care – September 22 Grantland — Dan Goldberg The Dr. Ralph and Marian Falk Medical Research Trust awarded a $485,000 grant to researchers from the Icahn School of Medicine at Mount Sinai and Thomas Jefferson University in Philadelphia to study why some uveal melanoma cancer cells lie dormant for years before spreading aggressively. - Icahn School of Medicine at Mount Sinai Learn more: http://www.politico.com/states/new-york/tipsheets/politico-new-york-health- care/2016/09/assemblyman-calls-for-broader-probe-bassett-on-zika-and-race-005202 Additional Coverage: News-Medical: http://www.news-medical.net/news/20160921/Mount-Sinai-and-TJU-researchers- awarded-Falk-Foundation-grant-for-UM-research.aspx

Politico Pulse – September 21 Names In The News: Jeffrey Sachs to Mount Sinai — Dan Diamond This appointment caught our eye: The Arnhold Institute for Global Health at the Icahn School of Medicine at Mount Sinai announced the economist and senior U.N. adviser will serve as a two-year fellow. What Dr. Sachs will examine: how New York City’s largest healthcare system, Mount Sinai, can contribute to the U.N.’s new Sustainable Development Goals. “The issues facing healthcare right now are not just of a clinical and operational nature, but connect to public policy and macroeconomics as well,” said Prabhjot Singh, MD, PhD, director of the Arnhold Global Health Institute. "We couldn’t be more proud to have the world’s thought leader on sustainable development." - Prabhjot Singh, MD, PhD, Senior Faculty, Medicine, General Internal Medicine, Director, Arnhold Global Health Institute, Chair, Department of Health System Design and Global Health, Icahn School of Medicine at Mount Sinai - Jeffrey D. Sachs, PhD, Visiting Fellow, Arnhold Institute for Global Health at the Icahn School of Medicine at Mount Sinai Learn more: http://www.politico.com/tipsheets/politico-pulse/2016/09/scoop-how-senate-will-get- around-planned-parenthood-issue-216443

Science Daily – September 21 Gene Therapy Technique May Help Prevent Cancer Metastasis A new gene therapy technique being developed by researchers at MIT is showing promise as a way to prevent breast cancer tumors from metastasizing. The treatment, described in a paper published in the journal Nature Communications, uses microRNAs -- small noncoding RNA molecules that regulate gene expression -- to control metastasis. "The research offers the potential for combined experimental therapeutics with traditional chemotherapy in cancer metastasis," said Julie Teruya-Feldstein, MD, a professor of pathology at the Icahn School of Medicine at Mount Sinai, who was not involved in the study. - Julie Teruya-Feldstein, MD, Professor, Pathology, Icahn School of Medicine at Mount Sinai Learn more: https://www.sciencedaily.com/releases/2016/09/160921101718.htm

New York 1 News (Time Warner Cable) – September 21 Transit Worker Donates Kidney So Co-Worker Can Move Up Transplant List — Jose Martinez Track workers George Muehlhaus and Victor Rivera are back on the job at the 38th Street Yard in Brooklyn, a long way from the chat that helped to save Rivera's life. In 2013, Rivera was diagnosed with kidney failure. Doctors said he would need dialysis and, one day, a transplant, to save his life. He and Muehlhaus have known each other since they were rookie track workers in Queens 17 years ago. But they were just acquaintances for most of that time, which made Muehlhaus's offer to donate a kidney all the more surprising. But the two were not a match so in July, when a matching organ became available for Rivera, he got his new kidney at The Mount Sinai Hospital, and Muehlhaus gave one of his away. - The Mount Sinai Hospital Learn more: http://www.ny1.com/nyc/all-boroughs/transit/2016/09/21/transit-worker-donates-kidney- so-co-worker-can-move-up-transplant-list.html

DNAinfo – September 21 What to Ask Your Doctor, From the Actors Who Know Them Best— Nicole Levy In one of her current roles, actress Erica Winn Ball plays a patient going to the doctor's office for some bloodwork results. The physician tells her she is HIV positive, and her script instructs her to cry on cue. But unlike most of her acting gigs, Ball has to deliver the same performance as many as 12 times a day for an audience of one. The mother of two works at the Icahn School of Medicine at Mount Sinai's Morchand Center as what is known in the healthcare field as a "standardized patient" or "SP." - Morchand Center, Icahn School of Medicine at Mount Sinai's Learn more: https://www.dnainfo.com/new-york/20160921/upper-east-side/3-lessons-every-patient-can- learn-from-actors-who-play-them

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Werle, Laura Subject: Mount Sinai In the News - September 21, 2016 Date: Wednesday, September 21, 2016 1:28:05 PM Attachments: ATT00002.txt

In the News September 21, 2016

Crain’s New York – September 21 Economist Jeffrey Sachs Begins Fellowship At Mount Sinai — Robin Schatz Economist Jeffrey Sachs has just begun a two-year visiting fellowship at the Arnhold Institute for Global Health at the Icahn School of Medicine at Mount Sinai, the health system announced Tuesday. In his new role, he'll help guide New York City's largest health care system to contribute to the United Nations' new Sustainable Development Goals. "Jeff Sachs has been at the forefront for supporting universal health coverage across the world and is a leader in establishing sustainable development goals,” Prabhjot Singh, MD, PhD, director of the Arnhold Global Health Institute at the Icahn School of Medicine at Mount Sinai, told Crain's. Dr. Sachs recently led a team of Mount Sinai executives, including Dr. Singh, to Ghana to observe how the west African nation is implementing an electronic health system. Dr. Singh said Dr. Sachs will interact with medical students, give lectures and work with the health system's business units to better understand the policy challenges they face. - Prabhjot Singh, MD, PhD, Senior Faculty, Medicine, General Internal Medicine, Director, Arnhold Global Health Institute, Chair, Department of Health System Design and Global Health, Icahn School of Medicine at Mount Sinai - Jeffrey D. Sachs, PhD, Visiting Fellow, Arnhold Institute for Global Health at the Icahn School of Medicine at Mount Sinai Learn more: http://www.crainsnewyork.com/article/20160921/PULSE/160929978/new-york-health-care- providers-find-savings-in-bundled-orthopedic

STAT News – September 21 Neighborhoods Influence Health, For Better And For Worse — Prabhjot Singh There’s a 10-year difference in life expectancy between residents of the Upper East Side and East Harlem. In other neighborhoods across the country, the gap is even larger. Such disparities reflect differences in the resources and infrastructures available in different communities, writes Prabhjot Singh, MD, PhD, chair of the department of health system design and global health at the Icahn School of Medicine at Mount Sinai. To address these inequities, health care systems must be understood as just one part of the complex, integrated community systems needed to support health. During this chaotic period of health care reform in America, doctors like me are waking up to a reality we have long ignored: To save lives, it simply isn’t enough to provide the best clinical care we can. As we transition from fee-for-service care to population health management, we must do more than “bend the cost curve” and provide health care more efficiently. - Prabhjot Singh, MD, PhD, Senior Faculty, Medicine, General Internal Medicine, Director, Arnhold Global Health Institute, Chair, Department of Health System Design and Global Health, Icahn School of Medicine at Mount Sinai Learn more: https://www.statnews.com/2016/09/21/health-neighborhoods-influence/

Fox News – September 20 Just Going On Vacation May Change Gene Activity In a new study comparing a meditation retreat with just relaxing in the same locale, both options improved stress regulation, immune function and other cellular markers in the blood. Researchers measured gene activity, blood markers and reported wellbeing during the vacation and months afterward, and found a large and immediate "vacation effect" in all participants. For those who continued meditating, benefits were seen even 10 months later. "We don't know what this means exactly, but given associations with biomarkers of aging, there is the potential that these changes could enhance overall wellbeing and longevity," said Eric Schadt, PhD, chair of the department of genetics and genomics at the Icahn School of Medicine at Mount Sinai. - Eric Schadt, PhD, Jean C. and James W. Crystal Professor of Genomics, Chair, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Founding Director, Icahn Institute for Genomics and Multiscale Biology Learn more: http://www.foxnews.com/health/2016/09/20/just-going-on-vacation-may-change-gene- activity.html

HealthDay News – September 20 Stress Might Undercut Benefits of Healthy Diet for Women — Dennis Thompson Stress could undo some of your healthy food choices, a new study suggests. Stressful events from the day before appear to eradicate any health benefits a person might have gained from choosing a breakfast rich in "good" monounsaturated fats. "As a registered dietitian, this study would not change my recommendations in regards to a healthy diet or one rich in monounsaturated fat compared to saturated fats," said Jennifer Kartashevsky, RD, a certified diabetes educator with the Diabetes Alliance Program at the Mount Sinai Health System. "The take away is to continuing to follow a diet rich in non-starchy vegetables, lean proteins, fresh fruits, whole grains and monounsaturated [fats] to give yourself a better base if stress does come your way." - Jennifer Kartashevsky, RD, CDE, Certified Diabetes Educator, Diabetes Alliance Program at the Mount Sinai Health System Learn more: https://consumer.healthday.com/mental-health-information-25/stress-health-news- 640/stress-might-undercut-benefits-of-healthy-diet-for-women-715012.html

WABC 7 – September 20 CDC Says FluMist Spray Ineffective, Recommends Shots — Michelle Charlesworth Three months ago the Centers for Disease Control recommended against using the FluMist spray, calling only flu shots effective, so now major insurance companies are not paying for the FluMist and doctors are not even stocking it. "It was ineffective yes, for the last three years when the shot was about 60% or better with a shot," said Roberto Posada, MD, an associate professor of pediatrics and infectious diseases at the Icahn School of Medicine at Mount Sinai, emphasizing the importance of vaccinations. "A lot of children end up coming to the emergency room, and across the U.S. dozens of them die each year.” - Roberto Posada, MD, Associate Professor, Pediatrics, Infectious Diseases, Medical Education, Icahn School of Medicine at Mount Sinai Learn more: http://abc7ny.com/health/cdc-says-flumist-spray-ineffective-recommends-shots/1519347/

CBS News – September 20 Will A Fitness Tracker Really Help You Lose Weight? — Mary Brophy Marcus A new study suggests the devices don’t improve weight loss for many people. The study comes “at a really crucial time” said Reshmi Srinath, MD, an assistant professor of endocrinology, diabetes and bone disease at the Icahn School of Medicine at Mount Sinai. “We know there’s more and more technology out there and the field is growing and growing. We need to do interventional studies.” Dr. Srinath also pointed out that most of the study’s participants were female and a majority of them were white. “With every study, you want to get the maximum patients possible, but we have to interpret those results in a certain context. We may not be able to generalize it to the greater population,” she explained. - Reshmi Srinath, MD, Assistant Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://www.cbsnews.com/news/fitness-trackers-may-not-help-with-weight-loss/ Additional Coverage: Medpage Today: http://www.medpagetoday.com/endocrinology/obesity/60342

Healthline – September 20 Is It Safe to Hit the Tennis Court with a New Hip? — Jenna Flannigan Joint replacements are increasingly offered to active patients at younger ages, but those considering surgery need to be realistic about the risks and benefits. In the past two years, Calin Moucha, MD, the chief of adult reconstruction and joint replacement surgery at The Mount Sinai Hospital, and his colleagues have noticed a 15 percent increase in patients under 60 having hip and knee joint replacement surgeries. Their observations align with recent research. At Mount Sinai, which was the official hospital of the U.S. Open, Dr. Moucha and his colleagues see an exceptional number of patients who play tennis. Dr. Moucha said that after a knee or hip replacement, “what’s dramatic to me is that a lot of these patients are able to return to tennis in a really exceptional capacity.” - Calin Moucha, MD, Assistant Professor, Orthopaedics, Icahn School of Medicine at Mount Sinai, Chief, Adult Reconstruction and Joint Replacement Surgery, The Mount Sinai Hospital Learn more: http://www.healthline.com/health-news/tennis-court-with-new-hip#1

Cardiovascular Business News – September 19 EBR Systems Receives FDA Approval to Start Clinical Trial of Its Wireless Cardiac Pacing System— Time Casey The FDA granted EBR Systems an investigational device exemption to begin a clinical trial to evaluate the company’s wireless cardiac pacing system for patients with heart failure. Vivek Reddy, MD, director of cardiac arrhythmia services for Mount Sinai Health System, presented results of EBR Systems’ SELECT-LV study in May at the Heart Rhythm Society scientific sessions in San Francisco. The study found that 34 of 35 patients who had failed conventional CRT therapy were implanted successfully with WiSE technology. In addition, 85 percent of patients improved their clinical composite score at six months. - Vivek Reddy, MD, MS, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Cardiac Arrhythmia Services, Mount Sinai Health System Learn more: http://www.cardiovascularbusiness.com/topics/technology-management/ebr-systems- receives-fda-approval-start-clinical-trial-its-wireless-cardiac-pacing-system

Health Imaging – September 20 Cancer-Detection Software Proves Worthy, Albeit Imperfect, ‘Second Reader’ of Lung CT — Dave Pearson Computer-aided detection (CAD) may be useful as a “second reader” of low-dose CT lung images, as four CAD systems in a small study found up to 70 percent of lung cancers a radiologist had missed yet missed around 20 percent of cancers that human eyes had caught. Corresponding author David Yankelevitz, MD, a professor of radiology at the Icahn School of Medicine at Mount Sinai, and colleagues report their findings in the October edition of Radiology. Of note, the team found clear differences in performance of the CAD systems. Some attained relatively high sensitivity for both nodule and cancer detection with a low rate of false-positive findings, while others, the authors write, “more heavily traded their increased sensitivity with the consequence of higher rates of false-positive findings.” - David Yankelevitz, MD, Professor, Radiology, Icahn School of Medicine at Mount Sinai, Director, Lung Biopsy Service, The Mount Sinai Hospital Learn more: http://www.healthimaging.com/topics/oncology-imaging/cancer-detection-software- proves-worthy-albeit-imperfect-%E2%80%98second-reader%E2%80%99-lung-ct

Practical Pain Management – September 20 Living with Unpredictable Pain: A Sickle Cell Disease Story Between 2004 and 2016, Vismel Marquez was hospitalized about ten times. Sometimes he’d spend three or four days in the hospital, be released, make it home only to have another crisis a few days later. “This follows the natural pattern of a pain crisis,” explains Jena Simon, MS, RN, a nurse practitioner in the Comprehensive Program for Sickle Cell Disease at The Mount Sinai Hospital. “It’s a well-documented phenomenon. This pattern can be very challenging and disheartening.” His mother, Vivian, 48, is a nurse in the Cardiac Care Unit at The Mount Sinai Hospital, where Vismel has been treated for sickle cell disease ever since the family emigrated from the Dominican Republic to the United States in 2003. - Jena Simon, MS, RN, Nurse Practitioner, Comprehensive Program for Sickle Cell Disease at The Mount Sinai Hospital Learn more: http://www.practicalpainmanagement.com/patient/resources/understanding-pain/living- unpredictable-pain-sickle-cell-disease-story

News Deeply – September 20 7 Experts to Watch on Health in Syria — Eline Gordts More than five years into the war, the public health sector in many parts of Syria is on the brink. Medical infrastructure, particularly in opposition-held areas of the country, has been crippled by frequent, targeted attacks. Roughly 95 percent of doctors have either fled or been detained or killed since the beginning of the crisis. Annie Sparrow, MD, an assistant professor of environmental medicine and public health at the Icahn School of Medicine at Mount Sinai, currently focuses on the Syrian conflict. Sparrow spends much time on the Turkey-Syrian border, documenting the health crisis and training Syrian medical workers. She has written extensively on the polio epidemic in the country, as well as the Assad regime’s use of chemical weapons and its attacks on the Syrian healthcare system. - Annie Sparrow, MD, Assistant Professor, Environmental Medicine and Public Health, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: https://www.newsdeeply.com/syria/articles/2016/09/20/7-experts-to-watch-on-health-in- syria Additional Coverage: Twitter: https://twitter.com/SyriaDeeply/status/778304992193241089

Consumer Reports – September 20 Easing Constipation, Heartburn, and Other Tummy Troubles — Hallie Levine People with frequent or long-term constipation often turn to OTC laxatives or are prescribed one by a doctor, but in most cases, that’s not a good idea. Stimulant laxatives can cause dependency as well as dizziness, diarrhea, and nausea. And stool softeners, such as docusate, don’t work better than a placebo, according to a June 2016 commentary in JAMA Internal Medicine. Trying a laxative that contains polyethylene glycol (MiraLax and generic) or lactulose is less likely to cause dependence, although it can lead to diarrhea and gas, says Ari Grinspan, MD, an assistant professor of medicine and gastroenterology at Icahn School of Medicine at Mount Sinai. - Ari Grinspan, MD, Assistant Professor, Medicine, Gastroenterology, Icahn School of Medicine at Mount Sinai Learn more: http://www.consumerreports.org/conditions-treatments/ease-constipation-heartburn-and- other-stomach-woes/

Health Magazine – September 20 Your Immune System — Hallie Levine A person’s immune system can only work, and protect the body from bad-news microbes on a daily basis, if you’re supplying the support it needs, says said E. Neil Schachter, MD, a professor of pulmonary medicine at the Icahn School of Medicine at Mount Sinai. There is a host of ways to boost immunity. - E. Neil Schachter, MD, Professor, Medicine, Pulmonary, Critical Care and Sleep Medicine, Pediatrics, Preventive Medicine, Icahn School of Medicine at Mount Sinai Learn more: No web link available.

Metro New York – September 20 Ask Mount Sinai: What You Need To Know About Prostate Cancer — Sheila Dougherty According to the Centers for Disease Control and Prevention, prostate cancer is the most common nonskin cancer among American men. September is National Prostate Cancer Awareness Month. We talked to Ash Tewari, MBBS, system chair of urology for the Mount Sinai Health System, about the risks and treatments, and the importance of screenings. “Treatment depends upon the stage. Very early cancer is best observed by active surveillance. Early cancer could be observed or treated by radiation, surgery or focal therapy. Advanced cancers need multimodality treatments,” Dr. Tewari said. - Ash Tewari, MBBS, MCh, Professor, Urology, Icahn School of Medicine at Mount Sinai, System Chair, Urology, Mount Sinai Health System Learn more: http://www.metro.us/new-york/ask-mount-sinai-what-you-need-to-know-about-prostate- cancer/zsJpiu---0XyUYAOic6lOM/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Werle, Laura Subject: Mount Sinai In the News - September 20, 2016 Date: Tuesday, September 20, 2016 2:44:57 PM Attachments: ATT00002.txt

In the News September 20, 2016

Wall Street Journal – September 19 Can Meditation Help Pain After Surgery? — Lucette Lagnado In a study at Mount Sinai Hospital in New York City, a neurosurgeon has teamed up with a geriatrician who leads meditation classes to test whether the technique can lessen pain in spine-surgery patients and reduce the need for opioid painkillers, which can be highly addictive. “We are not hoping to replace the need for pain medication,” says Patricia Bloom, an associate clinical professor of geriatrics at the Icahn School of Medicine at Mount Sinai, and a co-investigator on the project with colleague Arthur Jenkins, MD, an associate professor of neurosurgery at the Icahn School of Medicine at Mount Sinai. Dr. Jenkins says that during his 15 years practicing spine and neurosurgery, he has become increasingly open to other healing options, such as working with chiropractors as a complement or alternative to surgery. “I have evolved to a more holistic approach,” he says. - Patricia A. Bloom, MD, Associate Clinical Professor, Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, Director, Integrative Health, The Martha Stewart Center for Living at Mount Sinai - Arthur Jenkins III, MD, Associate Professor, Neurosurgery, Orthopaedics, Icahn School of Medicine at Mount Sinai Learn more: http://www.wsj.com/articles/can-meditation-help-pain-after-surgery-1474299114

TCT MD – September 19 Longer Term, IN.PACT SFA Trial and Global Registry Continue to Support DCB Therapy as an Option — L.A. McKeown In patients with symptomatic peripheral arterial disease, a drug-coated balloon (DCB) shows superior efficacy at 3 years compared with plain balloon angioplasty and performs well at 1 year in the real world outside of clinical trials, according to data released in two late-breaking presentations at VIVA 2016. Presenting the 3-year trial results from the IN.PACT SFA trial, Prakash Krishnan, MD, an assistant professor of cardiology at the Icahn School of Medicine at Mount Sinai, said “there really may not be a class effect” and that each of the DCBs need to be considered in the context of its own data. - Prakash Krishnan, MD, Assistant Professor, Medicine, Cardiology, Radiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.tctmd.com/show.aspx?id=136199

Drug Discovery and Development Magazine – September 20 Gene Therapy Technique Could Help Prevent Cancer Metastasis The spread of malignant cells around the body, known as metastasis, is the leading cause of mortality in women with breast cancer. Now, a new gene therapy technique being developed by researchers at MIT is showing promise as a way to prevent breast cancer tumors from metastasizing. The treatment, described in a paper published today in the journal Nature Communications, uses microRNAs — small noncoding RNA molecules that regulate gene expression — to control metastasis. “The research offers the potential for combined experimental therapeutics with traditional chemotherapy in cancer metastasis,” says Julie Teruya-Feldstein, MD, a professor of pathology at the Icahn School of Medicine at Mount Sinai, who was not involved in the study. - Julie Teruya-Feldstein, MD, Professor, Pathology, Icahn School of Medicine at Mount Sinai Learn more: https://www.dddmag.com/news/2016/09/gene-therapy-technique-could-help-prevent- cancer-metastasis Additional Coverage: New Kerala: http://www.newkerala.com/news/2016/fullnews-121261.html

The New Yorker – September 19 Bariatric Surgery: The Solution To Obesity? — Ricka Galchen Only in the past few years has bariatric surgery, once considered a high-risk and extreme measure, been transformed into a relatively standard, safe, and straightforward one. William Inabnet III, MD, site chair of surgery at Mount Sinai Beth Israel, was a member of the team of physicians that developed sleeve gastrectomy as a stand-alone procedure. For a surgery, which was performed laparoscopically, Dr. Inabnet was joined by then-surgical fellow Aida Taye Bellistri, MD; an anesthesiologist; and two surgical nurses. Laparoscopic surgery leads to less postoperative pain and a lower risk of hernias and infections than traditional open surgery. “I would see someone for their two-year postoperative appointment, and they would be off those medications, and they might have a baby with them, or a new job,” said Yulia Zak, MD, an assistant professor of surgery at the Icahn School of Medicine at Mount Sinai. “Obesity- related infertility or mobility issues were no longer a problem for them. There was no other field of medicine where I saw people’s lives improved so dramatically.” - William Inabnet III, MD, FACS, Eugene W. Friedman, MD, Professor of Surgery, Icahn School of Medicine at Mount Sinai, Site Chair, Department of Surgery, Mount Sinai Beth Israel, Surgical Director, Diabetes, Obesity and Metabolism Institute at the Icahn School of Medicine at Mount Sinai, Director, Endocrine Surgery Quality, Mount Sinai Health System - Yulia Zak, MD, Assistant Professor, Surgery, Icahn School of Medicine at Mount Sinai, Assistant Program Director, General Surgery Residency, Mount Sinai Beth Israel - Aida Taye Bellistri, MD, Assistant Professor, Surgery, Icahn School of Medicine at Mount Sinai Learn more: http://www.newyorker.com/magazine/2016/09/26/bariatric-surgery-the-solution-to-obesity

Politico Pro New York Health Care – September 20 Jeffrey Sachs Joins Mount Sinai — Dan Goldberg Best-selling author Jeffrey D. Sachs, PhD, accepted a visiting fellowship at the Arnhold Institute for Global Health at the Icahn School of Medicine at Mount Sinai, the school announced Tuesday. The fellowship will last through 2018. Dr. Sachs, according to a press release, will examine how Mount Sinai Health System can contribute to the UN's new Sustainable Development Goals, particularly Good Health and Well Being. - Jeffrey D. Sachs, PhD, Visiting Fellow, Arnhold Institute for Global Health at the Icahn School of Medicine at Mount Sinai Learn more: http://www.politico.com/states/new-york/tipsheets/politico-new-york-health- care/2016/09/medical-marijuana-investigation-mayors-management-report-005176

New York 1 News (Time Warner Cable) – September 17 NYer of the Week: Susie Hochenberg Donates Her Time to The Mount Sinai Hospital — John Schiumo The song is called "Bill." It's the one melody that volunteer Susie Hochenberg always plays inside the lobby at The Mount Sinai Hospital. It's a nod to her husband William, a former patient there. In 2013, Susie didn't hesitate to donate a kidney to her spouse of 30 years. Now, Susie pays it forward to other patients at the Recanati/Miller Transplantation Institute at The Mount Sinai Hospital. She donates her time by raising awareness about organ donations and providing comfort to patients using a blend of music and art. "I feel the rest of my life, as long as I can get up and do things, that I will give back to Mount Sinai," she says. "This is somebody who made one of the greatest gifts somebody can make, to give another person literally a part of themselves. And not only does she give her husband her kidney, but she also comes back and gives us her time and shows other patients that there's hope," says Sander Florman, MD, director of the Recanati/Miller Transplant Institute at The Mount Sinai Hospital. - Sander Florman, MD, Professor, Surgery, Icahn School of Medicine at Mount Sinai, Director, Recanati/Miller Transplantation Institute Learn more: http://www.ny1.com/nyc/all-boroughs/nyer-of-the-week/2016/09/17/nyer-of-the-week-- susie-hochenberg-donates-her-time-to-mount-sinai-hospital.html

Wall Street Journal – September 19 Adrian Peterson Has Torn Meniscus in Knee — Andrew Beaton The Vikings pulled off one of the biggest early wins of the NFL season on Sunday, beating the Packers 17-14, but they also potentially lost star running back Adrian Peterson. Peterson has a torn meniscus in his knee, coach Mike Zimmer said. If Peterson requires surgery, the duration of his absence will depend on the severity of the tear, said James Gladstone, MD, co-chief of the sports medicine service at The Mount Sinai Hospital. He could be back in 4-8 weeks, but that period could balloon to 3-4 months if the meniscus requires extensive repair, Dr. Gladstone said. - James Gladstone, MD, Associate Professor, Orthopaedics, Sports Medicine Service, Icahn School of Medicine at Mount Sinai, Co-Chief, Sports Medicine, The Mount Sinai Hospital Learn more: http://www.wsj.com/articles/adrian-peterson-has-torn-meniscus-in-knee-1474334794

Daily Mail – September 13 How Stress Makes It Harder To Conceive: Women Who Feel Overstretched 'Are 40% Less Likely To Get Pregnant' — Mia De Graaf Stressed women are 40 per cent less likely to conceive, a new study reveals. For years, doctors have said it seems relaxed and happy couples have a higher chance of getting pregnant. “A woman should not feel guilty or that there is something that she is doing wrong that is the cause of the infertility,” said Alan Copperman, MD, division director of reproductive endocrinology at the Icahn School of Medicine at Mount Sinai. “Lifestyle and wellness are important, but when a couple is facing reproductive obstacles, it is likely that the biological etiology related to egg quality, sperm function, or tubal and uterine issues, and not to mood and to personal and professional challenges.” - Alan Copperman, MD, Clinical Professor, Obstetrics, Gynecology, Reproductive Science, Division Director, Reproductive Endocrinology, Icahn School of Medicine at Mount Sinai Learn more: http://www.dailymail.co.uk/health/article-3787306/How-STRESS-makes-harder-conceive- Women-feel-overstretched-40-likely-pregnant.html

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Werle, Laura Subject: Mount Sinai In the News - September 19, 2016 Date: Monday, September 19, 2016 2:01:58 PM Attachments: ATT00002.txt

In the News September 19, 2016

Newsweek – September 18 Fallout From 9/11 Attacks On Par With Fukushima and Chernobyl, Researcher Says — Leah McGrath Goodman At a conference at the New York Academy of Medicine on Wednesday, researchers shared fresh evidence of elevated rates of cancer, heart and respiratory disease and post-traumatic stress disorder linked to Ground Zero. Previewing a yet-to-be-released paper, Roberto Lucchini, MD, director of the World Trade Center Data Center, at The Mount Sinai Hospital, compared the findings of health programs established around the world in the aftermath of major environmental disasters, including in downtown New York and Fukushima, Japan. “We are trying to look at what happened in each of these situations and what happened afterward to try to derive lessons,” he said. Mary Ann McLaughlin, MD, medical director of the cardiac health program at Mount Sinai Heart, presented data suggesting a link between cardiovascular risks, sleep apnea and mental-health issues in patients who breathed in the toxic dust of Ground Zero. “Being in the cloud seemed to lead to greater risk of PTSD and a stiffening of the heart,” she said. - Roberto Lucchini, MD, Professor, Environmental Medicine and Public Health, Medicine, Pulmonary, Critical Care, and Sleep Medicine, Icahn School of Medicine at Mount Sinai, Director, Division of Occupational Medicine, Director, World Trade Center Data Center, The Mount Sinai Hospital - Mary Ann McLaughlin, MD, Associate Professor, Medicine, Cardiology, Assistant Professor, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Medical Director, Cardiac Health Program, Co-Director, Women's Cardiac Assessment and Risk Evaluation Program at Mount Sinai Heart Learn more: http://www.newsweek.com/september-11-attacks-cancer-fukushima-chernobyl-downtown- manhattan-ground-zero-499883

Time Warner Cable News NY1 – September 7 As Years Go on, WTC Health Programs Shift to Meet Changing Needs — Erin Billups The World Trade Center Health programs for responders and for survivors took shape around the common ailments of those exposed to the cloud of toxic debris after the 9/11 attacks—asthma, sinusitis, acid reflux, and other problems that have only emerged more recently, including mental health issues and cancers. "The interaction of the problems was the first thing we started to notice that could significantly affect how people were doing," explains Michael Crane, MD, director of the World Trade Center Health Program Clinical Center of Excellence at Mount Sinai. - Michael Crane, MD, MPH, Associate Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital Learn more: http://www.ny1.com/nyc/all-boroughs/health-and-medicine/2016/09/7/as-years-go-on-- wtc-health-programs-must-shift-to-meet-unique-needs.html Additional Coverage: Time Warner Cable News NY1 (Spanish): http://www.ny1noticias.com/nyc/twc-ny1- noticias/noticias/2016/09/9/alex-sanchez--un-sobreviviene-del-9-11-que-nunca-se-ha-doblegado.html

Health Leaders Media – September 1 Patient Experience: One Person at a Time — Jennifer Thew Today more hospitals and health systems are moving beyond the silo of patient satisfaction in an attempt to improve patient experience through a variety of ways. Patient experience is all encompassing. "It's clinical. It's operational. It's behavioral. It's cultural. It's everything," says Sandra Myerson, MBA, RN, senior vice president and chief patient experience officer at the Mount Sinai Health System, an integrated system that sees 152,576 annual inpatient admissions. "It's every interaction patients have with anything within our healthcare system, whether it's someone on the telephone, whether it's a document they're reading, whether it's our website, whether it's the building—everything matters." - Sandra Myerson, MBA, MS, BSN, RN, Senior Vice President, Chief Patient Experience Officer, The Joseph F. Cullman, Jr. Institute for Patient Experience at The Mount Sinai Hospital Learn more: http://www.healthleadersmedia.com/nurse-leaders/patient-experience-one-person-time

Clinical Oncology – September 16 Novel Regimens Show Promise in Multiple Myeloma Novel drug combinations are showing promise in Phase I trials of patients with relapsed/refractory multiple myeloma (MM). Researchers reported results from the Phase I Keynote 023 study of the programmed death-1 inhibitor pembrolizumab. “Results support the continued investigation into the application of checkpoint modulators in multiple myeloma,” said Hearn Cho, MD, PhD, an assistant professor of hematology and medical oncology at the Icahn School of Medicine at Mount Sinai, who was not involved with the study. “The full benefit of checkpoint modulation in combination with other immunotherapies will ultimately be judged on whether they provide a PFS [progression-free survival] or overall survival benefit, and that remains to be seen.” - Hearn Cho, MD, PhD, Assistant Professor, Medicine, Hematology and Medical Oncology, The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai Learn more: http://www.clinicaloncology.com/Hematologic-Malignancies/Article/09-16/Novel- Regimens-Show-Promise-in-Multiple-Myeloma/37889

Medpage Today – September 17 Siponimod May Slow Worsening in SPMS — Kristina Fiore A novel sphingosine-1-phosphate (S1P) receptor modulator may stall disability progression in patients with secondary progressive MS, researchers reported. "I would offer this drug to my patients with the caveat that the efficacy was modest, and that the secondary endpoint of the timed 25-foot walk test was not met," said Aaron Miller, MD, professor of neurology at the Icahn School of Medicine at Mount Sinai, who was a site investigator in the trial. "Nonetheless, the options are very limited for patients with SPMS." - Aaron Miller, MD, Professor, Neurology, Icahn School of Medicine at Mount Sinai, Medical Director, Corinne Goldsmith Dickinson Center for Multiple Sclerosis Learn more: http://www.medpagetoday.com/meetingcoverage/ectrims/60297

MIT News – September 19 Gene Therapy Technique May Help Prevent Cancer Metastasis — Helen Knight The spread of malignant cells around the body, known as metastasis, is the leading cause of mortality in women with breast cancer. Now, a new gene therapy technique being developed by researchers at MIT is showing promise as a way to prevent breast cancer tumors from metastasizing. “The research offers the potential for combined experimental therapeutics with traditional chemotherapy in cancer metastasis,” says Julie Teruya-Feldstein, MD, a professor of pathology at the Icahn School of Medicine at Mount Sinai, who was not involved in the study. - Julie Teruya-Feldstein, MD, Professor, Pathology, Icahn School of Medicine at Mount Sinai Learn more: http://news.mit.edu/2016/gene-therapy-technique-prevent-cancer-metastasis-0919

Targeted Oncology – September 17 Expert Shares Strategies for Treating High-Risk ET, PV — Darcy Lewis When it comes to managing high-risk patients with essential thrombocythemia or polycythemia vera, John Mascarenhas, MD, an associate professor of hematology and medical oncology at the Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai, starts with risk stratification, he told colleagues during a "How I Treat" session at the second annual ASH Meeting on Hematologic Malignancies in Chicago. Dr. Mascarenhas began his remarks by reviewing the World Health Organization’s 2016 diagnostic criteria for both ET and PV.1 He noted that the PV criteria now include a bone marrow biopsy to make the diagnosis. - John Mascarenhas, MD, Associate Professor, Medicine, Hematology and Medical Oncology, Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai Learn more: http://www.targetedonc.com/conference/soho-2016/managing-highrisk-patients-with- essential-thrombocythemia-or-polycythemia-vera

Health Care Business Daily News – September 15 FDA Permits EBR Systems to Initiate Study For Wireless Cardiac Pacing System — Lauren Dubinsky About 30 percent of patients who receive conventional cardiac resynchronization therapy (CRT) don't respond to it — but the world's smallest, wireless implantable device for cardiac pacing may help solve that. The FDA has granted an Investigational Device Exemption for EBR Systems Inc.'s Wireless Stimulation Endocardially (WiSE) Technology for CRT. The company conducted a previous study called SELECT-LV and the results were presented in May by Vivek Reddy, MD, director of cardiac arrhythmia services for Mount Sinai Health System. - Vivek Reddy, MD, MS, Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai, Director, Cardiac Arrhythmia Services, Mount Sinai Health System Learn more: https://www.dotmed.com/news/story/32913

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Slotnick, David Subject: Mount Sinai In The News - September 16, 2016 Date: Friday, September 16, 2016 11:33:29 AM Attachments: ATT00002.txt

In the News September 16, 2016

NBC News – September 15 Many Trans Patients Face Fear, Stigma at Doctor's Office About 30 percent of transgender patients report delaying or not seeking care due to discrimination, according to a report published in the June edition of the journal Medical Care. One in four say they were denied equal treatment in healthcare settings. New York's Mount Sinai Health System culturally trains all employees at its seven hospitals who have any contact with transgender patients and in March opened the Center for Transgender Medicine and Surgery, offering integrated care. "Compared to where we were when I started trans work in the early '90s, we have made tremendous progress," said Barbara Warren, PsyD, director for LGBT Programs and Policies in the Office for Diversity and Inclusion at Mount Sinai Health System. - Barbara E. Warren, PsyD, Director, LGBT Health Services, Mount Sinai Beth Israel, Mount Sinai Health System, Director, LGBT Programs and Policies, Office for Diversity and Inclusion, Mount Sinai Health System Learn more: http://www.nbcnews.com/feature/nbc-out/many-trans-patients-face-fear-stigma-doctor-s- office-n648896

Marketplace – September 15 To Fix Health Care, Try A Walk Around The Neighborhood — Kai Ryssdal Prabhjot Singh, MD, PhD, director of the Arnhold Global Health Institute at the Icahn School of Medicine at Mount Sinai, spoke to Marketplace’s Kai Ryssdal about his book Dying and Living in the Neighborhood: A Street-Level View of America's Healthcare Promise. “At the heart of it, it’s not so much a question of getting physicians to walk around the neighborhood, but I think it’s also about letting people that are already in the community be representatives and also formally part of how we look at our health care system,” Dr. Singh said. “The only way to really move forward is to learn by doing and make sure that we actually can see the progress that we are making.” - Prabhjot Singh, MD, PhD, Senior Faculty, Medicine, General Internal Medicine, Director, Arnhold Global Health Institute, Chair, Department of Health System Design and Global Health, Icahn School of Medicine at Mount Sinai Learn more: http://www.marketplace.org/2016/09/15/health-care/fix-healthcare-try-walk-around- neighborhood

MD Magazine – September 13 Q&A with Karen M. Wilson: Pediatric Health Threat in Legal Marijuana? — Carolyn Colwell Colorado has legalized both medical and recreational use of cannabis. Karen M. Wilson, MD, now division chief of general pediatrics at the Kravis Children’s Hospital at Mount Sinai, and colleagues at Children’s Hospital Colorado decided to see if there were signs of unintended harm to children whose parents smoke marijuana. They found that most of a small group of children treated for bronchiolitis had marijuana metabolites in their urine. There’s no law against smoking in the presence of children, and Colorado laws require recreational marijuana to be smoked in private spaces. People who live in apartments don't have backyards and could be ticketed if they smoke it on the street. So the laws in Colorado, restricting use to private homes, encourages smoking around children since there is nowhere else to go.” - Karen M. Wilson, MD, Vice-Chair for Clinical and Translational Research, Icahn School of Medicine at Mount Sinai, Debra and Leon Black Division Chief, General Pediatrics, Kravis Children’s Hospital at Mount Sinai Learn more: http://www.hcplive.com/medical-news/qa-with-karen-m-wilson-pediatric-health-threat- in-legal-marijuana

Healio’s Psychiatric Annals – September 13 Individuals With Cocaine Addiction Most Vulnerable At Months 1, 6 Of abstinence — Amanda Olt Recent findings indicated individuals with cocaine addiction were most vulnerable to drug cues at 1 month and 6 months of abstinence, suggesting the significance of applying interventions at these time points. “The neuropsychological mechanisms of relapse remain poorly understood, but include the experience of intense craving for the drug elicited by cues or contexts previously associated with the drug,” Muhammad Parvaz, PhD, an assistant professor of psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai, and colleagues wrote. - Muhammad Parvaz, PhD, Assistant Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://www.healio.com/psychiatry/addiction/news/online/%7Bdf42f652-8554-49c4-9184- 8161497b7848%7D/individuals-with-cocaine-addiction-most-vulnerable-at-months-1-6-of-abstinence Additional Coverage: Psychiatric Advisor: http://www.psychiatryadvisor.com/addiction/surprising-trajectory-of-cocaine- craving-in-early-recovery/article/522974/

Medscape – September 16 UC: Symptoms Often Persist Despite Histologic Healing — Pam Harrison Patients with ulcerative colitis (UC) do not necessarily achieve complete relief of symptoms, especially with respect to stool frequency (SF), even when they do achieve endoscopic and histologic healing, according to results from an observational study published online September 2 in Gut. "Whether active histological inflammation in patients with endoscopic healing drives the persistence of symptoms in a subset of patients has not been evaluated," Jean-Frédéric Colombel, MD, director of the Susan and Leonard Feinstein IBD Clinical Center at Mount Sinai, and colleagues write. "Our work highlights the possibility that it may be very difficult for a therapy to achieve complete remission of symptoms even in the presence of endoscopic and histological healing." - Jean-Frédéric Colombel, MD, Professor, Medicine Gastroenterology, Icahn School of Medicine at Mount Sinai, Director, Susan and Leonard Feinstein IBD Clinical Center at Mount Sinai Learn more: http://www.medscape.com/viewarticle/868867

Medscape – September 16 Researchers Still Responding to Far-reaching Effects of 9/11 — Troy Brown Researchers from the World Trade Center (WTC) Health Program presented their findings on Wednesday about the effects of 9/11 on responders and survivors involved in the New York City attack. In addition to providing services to individuals, the program is also collecting and analyzing data at the macro level in the 9/11 cohort and conducting research. Approximately 90,000 people responded to hazardous sites, said Laura Crowley, MD, the deputy director of the World Trade Center Program Clinical Center of Excellence at Mount Sinai. Many were nontraditional volunteers. - Laura Crowley, MD, Assistant Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Deputy Director, World Trade Center Program Clinical Center of Excellence at Mount Sinai Learn more: http://www.medscape.com/viewarticle/868865

Medpage Today – September 15 Meeting Coverage: Second Chance for Cladribine? — Kristina Fiore Data from a pair of extension trials have bolstered the long-term safety and efficacy of oral cladribine for relapsing multiple sclerosis, researchers reported. "In our field over the last 5 or 6 years, there's been approval of other, more powerful medications, so this is now in the context where we have, for instance, alemtuzumab with its risks that patients are willing to take on," said Stephen Krieger, MD, an associate professor of neurology at the Icahn School of Medicine at Mount Sinai, who was not involved in the study. "We have a more nuanced understanding of Tysabri and PML and that risk that people are willing to take on." - Stephen Krieger, MD, Associate Professor, Neurology, Icahn School of Medicine at Mount Sinaiw Learn more: http://www.medpagetoday.com/meetingcoverage/ectrims/60241

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Werle, Laura Subject: Mount Sinai In the News - September 15, 2016 Date: Thursday, September 15, 2016 12:22:58 PM Attachments: ATT00003.txt

In the News September 15, 2016

JAMA – September 14 Call to Action on Neurotoxin Exposure in Pregnant Women and Children — Jennifer Abbasi Citing an alarming increase in childhood neurodevelopmental disorders, such as autism and attention- deficit/hyperactivity disorder, a group of scientists, health professionals and children’s health advocates is calling for increased monitoring, assessment, and reduction of neurotoxic chemicals. The Targeting Environmental Neuro-Developmental Risks (TENDR) Consensus Statement is “a call to action to reduce exposures to toxic chemicals that can contribute to the prevalence of neurodevelopmental disabilities in America’s children.” “There has been an explosion of knowledge in the past decade showing that quite a long list of commonly used chemicals are capable of causing neurodevelopmental damage to children, especially if the exposure occurs in utero during the nine months of pregnancy or in the first few years after birth,” said Philip Landrigan, MD, the dean for global health at the Icahn School of Medicine at Mount Sinai, and one of 47 coauthors on the consensus statement. - Philip Landrigan, MD, MSc, Professor, Environmental Medicine and Public Health, Pediatrics, Dean for Global Health, Icahn School of Medicine at Mount Sinai Learn more: http://jama.jamanetwork.com/article.aspx?articleid=2553337

CNN – September 14 NFL Announces $100 Million Concussion Initiative — Susan Scutti National Football League Commissioner Roger Goodell announced Wednesday an initiative intended to increase the safety of the game, specifically by preventing, diagnosing and treating head injuries. "Anytime the NFL brings this up, it shines more light on the problem," said Sam Gandy, MD, PhD, director of the Center for Cognitive Health at The Mount Sinai Hospital, whose research is not funded by the NFL. Mount Sinai's center is one of five where a retired player experiencing neurological issues can come for an evaluation. Although the evaluation is funded by the NFL, ongoing treatment is not, and Dr. Gandy's services are voluntary. "Physicists and imaging people and biochemists have been working on this problem for some time," he said, explaining how until recently, CTE has only been diagnosed in postmortem brains, never in live brains. - Samuel Gandy, MD, PhD, Professor, Neurology, Psychiatry, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Center for Cognitive Health, Associate Director, Mount Sinai Alzheimer's Disease Research Center, Director, NFL Neurological Care Program at The Mount Sinai Hospital Learn more: http://www.cnn.com/2016/09/14/health/nfl-concussion-safety-initiative/index.html

Reuters – September 14 Cocaine Addicts Often Unaware Of Their Risk For Relapse — Marilynn Larkin Objective measures of cue-induced craving show abstaining cocaine addicts are often unaware of their risk for relapse, researchers report. "Our results could help guide the implementation of alternative, individually tailored and optimally timed intervention, prevention and treatment strategies," said Rita Goldstein, PhD, a professor of psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai. Coauthor Muhammad Parvaz, PhD, an assistant professor of psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai, added, "This study also highlights the use of scientific tools and techniques that quantify brain activity to objectively assess relapse vulnerability." Such tools could be integrated into clinical practice, he said. - Rita Goldstein, PhD, Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai, Chief, Brain Imaging Core, Director, Neuropsychoimaging of Addiction and Related Conditions Research Program - Muhammad Parvaz, PhD, Assistant Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://www.mdalert.com/news/article/cocaine-addicts-often-unaware-of-their-risk-for- relapse

Crain’s Health Pulse – September 15 Researchers Reveal Health Lessons From 9/11 — Caroline Lewis Fifteen years after the terrorist attacks of 9/11, researchers are continuing to document new long-term health effects suffered by thousands of rescue workers and others who were exposed to conditions around the World Trade Center site. Dedicated programs like Mount Sinai's World Trade Center Health Program, and the World Trade Center Health Program launched shortly after the attacks by the FDNY Bureau of Health Services, have facilitated research not only on the health impacts of 9/11 but also on treatment methods used to address them. These issues were highlighted during a conference hosted by Mount Sinai in Manhattan on Wednesday. Informing firefighters present during 9/11 that they could be at increased risk for certain health conditions helped get them involved in the program. - World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital Learn more: http://www.crainsnewyork.com/article/20160915/PULSE/160919933/mount-sinai-doc- draws-inspiration-from-patients-funeral-in-new-book

Reuters – September 15 Transgender Patients Face Fear And Stigma In The Doctor's Office — Daniel Trotta The same rejection many transgender people confront at home and in society can often await them in the doctor's office, where many report being harassed, ridiculed or even assaulted. Society is gradually learning the basics of gender identity, but the medical profession has been slow to adapt, according to leaders in transgender medicine, transgender advocates and patients. The picture is not universally grim for transgender patients, who say medical professionals have become more adept in recent years, especially at large medical centers in big cities. Mount Sinai Health System trains all employees at its seven hospitals, who have any contact with transgender patients. In March, they opened the Center for Transgender Medicine and Surgery, which offers integrated care. "Compared to where we were when I started trans work in the early '90s, we have made tremendous progress," said Barbara Warren, PsyD, director for LGBT Programs and Policies in the Office for Diversity and Inclusion at Mount Sinai Health System. - Barbara E. Warren, PsyD, Director, LGBT Health Services, Mount Sinai Beth Israel, Mount Sinai Health System, Director, LGBT Programs and Policies, Office for Diversity and Inclusion, Mount Sinai Health System. Learn more: http://www.reuters.com/article/us-usa-lgbt-medicine-idUSKCN11L0AJ

STAT News – September 14 Tough Call For Surgeons: Should They Tell Transplant Patients Their Donor Was An Addict? — Eric Boodman This dilemma has become surprisingly common for transplant patients, as the nation’s opioid epidemic yields a tragic surge in organ donors. And surgeons themselves face a quandary: How much of the overdose victim’s story should they reveal to desperate transplant candidates? Sander Florman, MD, director of the Recanati/Miller Transplant Institute at the Icahn School of Medicine at Mount Sinai, said it’s quite possible that patients will decide to reject an organ because of stigma, but it doesn’t worry him. After all, there were about 120,000 Americans waiting for transplants in late July. “The harsh reality is that most of those people waiting for a kidney are not going to get one. They’re going to die while they’re on dialysis. There just aren’t enough organs,” he said. “We have over 1,650 people waiting for a kidney here. If one person says no, the next 10 will say yes.” - Sander Florman, MD, Professor, Surgery, Icahn School of Medicine at Mount Sinai, Director, Recanati/Miller Transplant Institute Learn more: https://www.statnews.com/2016/09/14/organ-tranplants-addiction-disclosure/

Crain’s Health Pulse – September 15 Mount Sinai Doc Draws Inspiration From Patient's Funeral In New Book: Interview — Robin Schatz In the summer of 2011, Prabhjot Singh, MD, PhD, then a clinical resident at Mount Sinai Health System, first met the patient he calls Ray in the emergency room. Ray was suffering from uncontrolled diabetes, high blood pressure, an irregular heartbeat and a dangerous blood clot in his right thigh that was migrating toward his heart. Ray is actually a composite character, drawing details from the lives of four patients with similar conditions and circumstances to protect his privacy. Dr. Singh, who is now director of the Arnhold Institute for Global Health at the Icahn School of Medicine, spoke to Crain's about his book, which blends personal reflection with extensive research into how health care innovators are focusing on neighborhood health. - Prabhjot Singh, MD, PhD, Senior Faculty, Medicine, General Internal Medicine, Director, Arnhold Global Health Institute, Chair, Department of Health System Design and Global Health, Icahn School of Medicine at Mount Sinai Learn more: http://www.crainsnewyork.com/article/20160915/PULSE/160919933/mount-sinai-doc- draws-inspiration-from-patients-funeral-in-new-book

Self – September 14 Weighing The Pros And Cons Of Wet Wipes Vs. Traditional Toilet Paper — Korin Miller Wet wipes for adults to use in the bathroom are becoming more common, but their utility compared to using toilet paper is unclear. While wet wipes may get your behind squeaky clean, they can actually cause irritation. “Whenever I see it, patients are usually using very soft toilet paper or wet wipes,” said Gary Goldenberg, MD, an assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai. “Sometimes switching to the most basic (usually the cheapest) toilet paper may improve the problem, along with other treatments.” - Gary Goldenberg, MD, Assistant Professor, Dermatology, Pathology, Icahn School of Medicine at Mount Sinai, Director, Dermatology Faculty Practice, The Mount Sinai Hospital Learn more: http://www.self.com/trending/2016/09/flushable-wipes-vs-toilet-tissue/

Thrillist – September 14 NYC Doctors Tell Us What Iconic Local Foods They Absolutely Refuse To Eat — Meagan Drillinger When it comes to NYC foods, not all are created equal, especially in the eyes of medical professionals. We spoke to several NYC-area doctors, who basically shattered our realities by pointing out which iconic New York City foods (and some drinks) should remain off our menus, for the sake of our health. “You have to watch your liquid calories,” said Shanna Levine, MD, a primary care physician and clinical instructor of medicine at the Icahn School of Medicine at Mount Sinai. “People don’t realize that when they order their iced-tea lemonades or fancy lattes that these are equivalents of meals in terms of calories.” - Shanna Levine, MD, Instructor, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.thrillist.com/eat/new-york/unhealthy-nyc-foods-doctors-refuse-to-eat

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Werle, Laura Subject: Mount Sinai In the News - September 14, 2016 Date: Wednesday, September 14, 2016 4:09:20 PM Attachments: ATT00002.txt

In the News September 14, 2016

CBS Newspath – September 9 Cancer Is A Big Concern After September 11th Attack Fifteen years after the world trade center attacks, cancer remains one of the biggest concerns for first responders, survivors and residents. So far, more than five thousand have been diagnosed with cancers related to 9/11. Michael Crane, MD, director of the World Trade Center Health Program Clinical Center of Excellence at Mount Sinai, says doctors in his program are now diagnosing 10-15 new cancer cases each week including rare cancers, like carcinoid. - Michael Crane, MD, MPH, Associate Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital Learn more: http://5newsonline.com/2016/09/09/cancer-is-a-big-concern-after-september-11th-attack/

PIX 11 – September 13 Brooklyn Woman Who Lost Eyesight After Stabbing Can See Again Thanks to Mount Sinai Doctors Julissa Marquez was viciously stabbed by her ex-husband several years ago. Now, thanks to Ronald Gentile, MD, director of the Ocular Trauma Service at New York Eye and Ear Infirmary of Mount Sinai, and others at the New York Eye and Ear Infirmary of Mount Sinai, Marquez is slowly regaining eyesight and has a "glass half full" attitude. “Her injury is very severe and she needed 10 surgeries to get where she is today,” said Dr. Gentile. “She’s a real inspiration to anyone that knows her story, because to her the glass is half full and not half empty. These are the patients that tend to do the best.” - Ronald C. Gentile, MD, Professor, Ophthalmology, Icahn School of Medicine at Mount Sinai, Director, Ocular Trauma Service, Surgeon Director, New York Eye and Ear Infirmary of Mount Sinai Learn more: http://pix11.com/2016/09/13/brooklyn-woman-who-lost-eyesight-after-stabbing-can-see- again-thanks-to-mt-sinai-doctors/

WCBS 880 – September 14 Health and Well Being — Pat Farnack Joshua Bederson, MD, chairman of neurosurgery for Mount Sinai Health System, joins Pat Farnack to discuss the latest virtual reality technology, CaptiView, used in the operating room. “We now are trying to project the 3-D simulation into the eye pieces of the microscope, linking it to the patient’s specific anatomy, and then using all of that information during surgery to guide the operation,” Dr. Bederson says. - Joshua Bederson, MD, Professor, Neurosurgery, Icahn School of Medicine at Mount Sinai, System Chair, Neurosurgery, Mount Sinai Health System Learn more: http://newyork.cbslocal.com/audio/health-and-well-being/

Spire Healthcare – September 12 Protein Identified As Potential Therapeutic Target For Cancer Treatment S scientists have identified a protein that offers potential as a target for future cancer treatments. A team from the Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai examined a protein, known as kinase suppressor of Ras (KSR), a pseudoenzyme that plays a key role in transmitting signals in the cell to determine whether it will grow, divide or die. "Our study opens the possibility of modulating KSR as a new cancer therapy and also potentially an entirely new class of interventions," said lead researcher Arvin Dar, PhD, an assistant professor of oncological sciences at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai. - Arvin Dar, PhD, Assistant Professor, Oncological Sciences, Pharmacological Sciences, The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai Learn more: http://www.spirehealthcare.com/patient-information/health-news/cancer/801825049- protein-identified-as-potential-therapeutic-target-for-cancer-treatment/

Cardiology Advisor – September 13 Assessing Effect of Obesity on LVAD Outcomes — Britt Gambino In patients with obesity undergoing implantation with a left ventricular assist device (LVAD) as a bridge to transplantation, weight loss was possible, but not typical, according to research published in JACC: Heart Failure. Investigators from Icahn School of Medicine at Mount Sinai and New York-Presbyterian Hospital/Columbia University Medical Center concluded that bridge to transplantation using LVADs should be carefully considered in patients with class II obesity or greater, and a multidisciplinary team may be the best approach to help these patients lose weight. “Otherwise, the waiting list will continue to expand with patients with a decreased chance of transplantation and have worse outcomes after transplantation,” they wrote. - Icahn School of Medicine at Mount Sinai Learn more: http://www.thecardiologyadvisor.com/interventional/lvad-implantation-transplantation- obesity/article/522324/

MD Magazine – September 14 Studying Gender and Race Differences in Robotic Surgery As robotic surgery has become more popular in fields like urology and gynecology questions have been raised about who is most likely to undergo these procedures and why that is the case. Michael Palese, MD, chair of the department of urology at Mount Sinai Beth Israel, discussed the results of the study with MD Magazine. Dr. Palese was part of a team that presented the research at Minimally Invasive Surgery Week in Boston. The study was focused on procedures done in New York State starting in 2009 to see if there were any trends in the usage of robotic procedures. Dr. Palese said there is not a gender or racial bias in the procedures but rather a change in the patient population who have pursued this as a treatment option in that time - Michael Palese, MD, Associate Professor, Urology, Icahn School of Medicine at Mount Sinai, Chair, Department of Urology, Mount Sinai Beth Israel, Director, Minimally Invasive Surgery, Mount Sinai Health System Learn more: http://www.hcplive.com/medical-news/michael-palese-from-mount-sinai-health-system- studying-gender-and-race-differences-in-robotic-surgery

General Surgery News – September 13 Few Women in Top Posts Despite Gains in Overall Ranks — Victoria Stern Over the last half-century, the landscape for women in surgery has transformed. Today, women comprise almost half of medical school graduates and residents, according to a 2014 report from the Association of American Medical Colleges (AAMC). Even so, according to AAMC data, women make up about 38% of surgical residents, 25% of assistant professors of surgery, 17% of associate professors, 9% of full professors and only 1% of chairs of surgery. “The data is pretty worrying,” said Patricia Sylla, MD, an associate professor of surgery at the Icahn School of Medicine at Mount Sinai. “We have an increasing number of surgical residents compared to 20 years ago, but along the pipeline you get fewer female associates and even fewer full professors and department chairs. It’s important to figure out what might account for this leaky pipeline.” - Patricia Sylla, MD, Associate Professor, Surgery, Icahn School of Medicine at Mount Sinai Learn more: http://www.generalsurgerynews.com/In-the-News/Article/09-16/Few-Women-in-Top- Posts-Despite-Gains-in-Overall-Ranks/37814

Ring Sider Report – September 13 The NFL Sidesteps Jets/Bills Color-Blindness Issue Last year, the NFL’s Color Rush Uniform series saw the Jets dressed in special all-green uniforms while the Bills wore all red. And the problem that emerged as a result of these color choices caught the NFL completely off guard. Color blind fans couldn’t tell the Jets and the Bills apart. The two teams will clash once more on Thursday night in Buffalo in 2016’s first color rush game. And naturally, the NFL is taking steps to prevent a repetition of last year’s conundrum. Heading into this season, the NFL was smart to consult a color-blindness expert. They found one in Scott E. Brodie, MD, PhD, a professor of ophthalmology at the Icahn School of Medicine at Mount Sinai. Along with two colleagues, Dr. Brodie received and reviewed all 15 combinations of the league’s Rush Color games for 2016. - Scott E. Brodie, MD, PhD, MA, Professor, Ophthalmology, Icahn School of Medicine at Mount Sinai, Director, Clinical Electrophysiology Laboratory Learn more: http://ringsidereport.com/?p=63065

Time – September 14 Assad’s Regime Is Still Using Chemical Weapons in Syria — Jared Malsin Physicians and human rights advocates argue that chlorine attacks are designed to sow terror, rather than cause mass casualties. Unlike ordinary bombs, or the makeshift barrel bombs used by the Assad regime, there is no sheltering underground from toxic gasses. Chlorine can be deadly. As victims inhale, it reacts with the lungs, turning into hydrochloric acid. “It dissolves the lungs as you breathe it in, and that’s how kids usually die,” said Annie Sparrow, MD, an assistant professor of environmental medicine and public health at the Icahn School of Medicine at Mount Sinai, who has worked closely with doctors in Syria. - Annie Sparrow, MD, Assistant Professor, Environmental Medicine and Public Health, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://time.com/4492670/syria-chemical-weapon-aleppo-assad-regime/

Huffington Post – September 13 Shingles, A Painful Rash Lying In Wait — Sam Altstein, DO Red bumps, blisters, and pain: These are the symptoms that about one million Americans will suffer this year when they develop the viral infection commonly known as shingles. The single thing you can do to prevent shingles is get a shingles vaccine, which a large study has shown to significantly reduce one’s risk for this disease, writes Sam Altstein, DO, an assistant professor of family medicine at the Icahn School of Medicine at Mount Sinai. - Samuel Altstein, DO, Assistant Professor, Family Medicine, Icahn School of Medicine at Mount Sinai, Attending, Department of Family Medicine, Mount Sinai Beth Israel Learn more: http://www.huffingtonpost.com/mount-sinai-health-system/shingles-a-painful-rash- l_b_11993696.html

Women’s Health – September 12 Causes of “Hanger” and How To Avoid It — Alison Feller “Hanger” isn’t just in your head—it’s a physiological and emotional response to hunger. “The feeling stems from a drop in blood glucose, which typically occurs when we go too long without eating or consume too many simple carbohydrates at one time,” says Kelly Hogan, MS, RD, a clinical nutrition coordinator at the Dubin Breast Center of the Tisch Cancer Institute of Mount Sinai. "Then, the body tries to raise its own blood sugar levels, including the release of stress hormones cortisol and adrenaline —both of which are linked to aggression, and may cause us to react more quickly in a less than desirable way.” - Kelly Hogan, MS, RD, CDN, Clinical Nutrition Coordinator, The Dubin Breast Cancer of the Tisch Cancer Institute at Mount Sinai Learn more: http://www.womenshealthmag.com/food/best-foods-for-when-youre-hangry/slide/1

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily on behalf of Werle, Laura Subject: Mount Sinai In the News - September 13, 2016 Date: Tuesday, September 13, 2016 2:09:23 PM Attachments: ATT00002.txt

In the News September 13, 2016

Newsday – September 12 Experts: Prostate Cancer, Cardiac Troubles Emerge As WTC Maladies — Delthia Ricks Prostate cancer, premature stiffening of the heart and thyroid malignancies among first responders and others who worked at Ground Zero are emerging as key medical concerns. Newly identified biomarkers — specific proteins in the blood — are helping doctors better understand prostate malignancies, according to health experts. “We are seeing some very young men with prostate cancer. The youngest one is 34,” said Michael Crane, MD, director of the World Trade Center Health Program Clinical Center of Excellence at Mount Sinai, sponsor of a symposium on World Trade Center Disorders at the New York Academy of Medicine. Mary Ann McLaughlin, MD, medical director of the cardiac health program at Mount Sinai Heart, is studying another anomaly that might afflict first responders and other workers who were at Ground Zero. “We’re trying to make sure they are treated now so that this problem doesn’t develop into a future risk,” she said. - Michael Crane, MD, MPH, Associate Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital - Mary Ann McLaughlin, MD, Associate Professor, Medicine, Cardiology, Assistant Professor, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Medical Director, Cardiac Health Program, Co-Director, Women's Cardiac Assessment and Risk Evaluation Program at Mount Sinai Heart Learn more: http://www.newsday.com/news/health/experts-prostate-cancer-cardiac-troubles-emerge- as-wtc-maladies-1.12304229 Additional Coverage: Pittsburgh Post-Gazette: http://www.post-gazette.com/news/health/2016/09/13/Experts-list-health- concerns-linked-to-9-11-terror-attacks/stories/201609130086

Becker’s Hospital CFO – September 12 Many 9/11 Victims, Responders Don't Know Their Medical Costs Are Covered — Brooke Murphy Congress established the federal World Trade Center Health Program in 2011 to cover medical expenses for responders, survivors and New York residents effected by or involved in events on 9/11. President Barack Obama signed legislation in May extending the program until 2090. But there are many people who qualify for full medical coverage who haven't signed up, according to Business Insider. "There's still a good chunk of folks out there who responded to the event and most likely have not been seen by anybody yet," said Michael Crane, MD, director of the World Trade Center Health Program Clinical Center of Excellence at Mount Sinai. These people may have received cancer diagnoses in other states and have not connected it to events from 15 years ago, Dr. Crane said. - Michael Crane, MD, MPH, Associate Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital Learn more: http://www.beckershospitalreview.com/finance/many-9-11-victims-responders-don-t- know-their-medical-costs-are-covered.html

NFPA Journal – September 12 Danger in the Dust — Jesse Roman According to the Centers for Disease Control (CDC), since the events of 9/11, at least 1,140 people enrolled in the World Trade Center Health Program—first responders, rescue and recovery workers, construction and utility workers, residents—have died, many from cancers and respiratory illnesses that medical professionals attribute in part to the toxic stew of chemicals and substances they inhaled near Ground Zero. NFPA Journal spoke with Michael Crane, MD, director of the World Trade Center Health Program Clinical Center of Excellence at Mount Sinai, about the WTC Health Program, health trends among rescue and recovery workers at Ground Zero, and the inspiration he takes from the responders he meets every day. “These guys were totally selfless, altruistic individuals who were also there because their sense of family had taken this huge hit. They had suffered personal losses and the way they were responding to all that grief was to go out and try and serve other people,” he said. - Michael Crane, MD, MPH, Associate Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital Learn more: http://www.nfpa.org/news-and-research/publications/nfpa-journal/2016/september- october-2016/pov/perspectives

Fox News – September 12 Cocaine Addiction Triggers Researchers from the Icahn School of Medicine at Mount Sinai believe they have pinpointed when adults addicted to cocaine are more vulnerable to relapse. For the first time in an addiction study, researchers used an electroencephalogram to measure cravings instead of relying on self-reported data. Study authors call the findings alarming, since it appears that the most intense periods of cravings often coincide with a patient’s release from addiction treatment programs, and they hope their research may be used to help guide timed intervention, prevention and treatment strategies. - Icahn School of Medicine at Mount Sinai Learn more: http://www.myfoxzone.com/news/health/cocaine-addiction-triggers/317273111

OncLive – September 12 Dr. Sundar Jagannath Comments on Three-Drug Regimen for Newly Diagnosed Multiple Myeloma There was a pivotal trial reported at the 2015 American Society of Hematology (ASH) meeting which demonstrated that a three-drug regimen was better than a two-drug regimen for multiple myeloma induction therapy. In response, Sundar Jagannath, MD, director of the multiple myeloma program at the Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai, discusses optimal induction therapy for multiple myeloma. - Sundar Jagannath, MD, Professor, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, Director, Multiple Myeloma Program, The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai Learn more: http://www.onclive.com/onclive-tv/dr-sundar-jagannath-on-threedrug-regimen-for-newly- diagnosed-multiple-myeloma

Sports Business Daily – September 12 US Open and High Tech Imaging The US Open worked with Mount Sinai Health Systems to use more high-tech medical imaging to better coordinate athletes’ treatments. Previously, when an athlete went for a scan at The Mount Sinai Hospital, a CD had to be taken back to the tennis center to coordinate decisions on whether the player could return. Now that information comes through digitally. Mount Sinai Health System has been the Open’s health care provider for the past four tournaments. - Mount Sinai Health System Learn more: https://www.sportsbusinessdaily.com/Journal/Issues/2016/09/12/Events-and- Attractions/US-Open-notebook.aspx (subscription required)

TCT MD – September 12 Stroke Risk With TAVR: In-Depth Review of PARTNER and CoreValve Data Reveals Opportunities and Unknowns — Shelley Wood Two comprehensive analyses of cerebrovascular events in the major randomized controlled trials of transcatheter aortic valve replacement are shedding new light on both the timing and risk factors for stroke in this setting. They also underscore the many unknowns the field is confronting as it moves into younger and lower-risk patients. Commenting on the two papers for TCTMD, George Dangas, MD, PhD, an assistant professor of cardiology at the Icahn School of Medicine at Mount Sinai, admitted he was “a little astonished by how different [the stroke predictors] were.” Dr. Dangas, with Gennaro Giustino, MD, a postdoctoral fellow in interventional cardiology at the Icahn School of Medicine at Mount Sinai, authored an editorial accompanying the two papers. - George Dangas, MD, PhD, Assistant Professor, Medicine, Cardiology, Surgery, Icahn School of Medicine at Mount Sinai, Director, Cardiovascular Innovation, Zena and Michael A. Wiener Cardiovascular Institute - Gennaro Giustino, MD, Postdoctoral Clinical Research Fellow, Interventional Cardiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.tctmd.com/show.aspx?id=136171

TAP Into: Flemington/Raritan – September 12 HCHS Grad to Receive Mount Sinai Beth Israel Honor — Tapinto Flemington-Raritan A 1986 Hunterdon Central High School graduate will be honored by the Louis Armstrong Center for Music and Medicine at Mount Sinai Beth Israel this month. Sharon Mahn will receive the What a Wonderful World Award, which she’ll share this year with five-time Grammy winner Dionne Warwick and Michael Leitman, MD, chair of surgery at Mount Sinai Beth Israel. The annual What a Wonderful World award is presented to a physician, a patient, and a philanthropist who have served to make the world better. - Michael Leitman, MD, Professor, Medical Education, Surgery, Senior Associate Dean for Graduate Medical Education, Icahn School of Medicine at Mount Sinai, Site Chair, Surgery, Mount Sinai Beth Israel Learn more: https://www.tapinto.net/towns/flemington-slash-raritan/articles/hchs-grad-to-receive- mount-sinai-beth-israel-hono

Momtastic Health – September 12 Tricks Pediatricians Use to Keep Their Own Kids Healthy — Alex Richards Pediatricians with kids must have so many great tricks for keeping their own kids healthy, right? I asked around, and it turns out doctors and nurses with kids have some awesome health tips. “Breakfast is a good place to start if possible,” says Maida P. Galvez, MD, an associate professor of preventive medicine at the Icahn School of Medicine at Mount Sinai. “I try to give my son one of his favorite fruits or vegetables with breakfast so I know he’s off to a good start.” - Maida Galvez, MD, MPH, Associate Professor, Preventive Medicine, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://www.momtastic.com/health/642477-tricks-pediatricians-use-to-keep-their-own-kids- healthy/

Shape – September 12 Why Women Who Exercise Are Also More Likely to Drink Alcohol — Sara Angle Not only do people drink more on days when they hit the gym, according to research published in the journal Health Psychology, but women who imbibe moderately (meaning four to seven drinks a week) are twice as likely to work out than their peers who abstain, a new study reports. Alcohol consumption and exercise can present a dangerous one-two punch. Alcohol can cause low blood sugar, even the next morning, leaving you shaky or weak, says Melissa Leber, MD, the director of emergency department sports medicine at Mount Sinai St. Luke’s and Mount Sinai West. - Melissa Leber, MD, Assistant Professor, Orthopaedics, Emergency Medicine, Director, Emergency Department Sports Medicine, Mount Sinai St. Luke’s, Mount Sinai West Learn more: http://www.shape.com/healthy-eating/healthy-drinks/why-women-who-exercise-are-also- more-likely-drink-alcohol

Reader’s Digest – September 12 9 Sneaky Signs You Might Be Drinking Too Many Calories — Alyssa Jung Unless you’re drinking water, beverages can add a lot of sneaky calories to your daily diet. Store-bought smoothies, for example, often rack up the sugar content by adding juice on top of fresh fruit, and use fatty bases instead of skim milk or low-fat yogurt, which can all add up to hundreds of calories. I always recommend my patients make their own smoothie. That way they can keep it low-calorie,” says Shanna Levine, MD, a primary care physician and clinical instructor of medicine at the Icahn School of Medicine at Mount Sinai. - Shanna Levine, MD, Instructor, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.rd.com/health/diet-weight-loss/drink-calories/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Werle, Laura Subject: Mount Sinai In the News - September 12, 2016 Date: Monday, September 12, 2016 12:38:59 PM Attachments: ATT00002.txt

In the News September 12, 2016

MSNBC – September 11 Security and Health Concerns Continue After 9/11 There are still several unanswered questions about Homeland Security and the ongoing health problems of 9/11 first responders 15 years after the attacks. Former Homeland Security advisor for New York state, Michael Balboni, and Michael Crane, MD, director of the World Trade Center Health Program Clinical Center of Excellence at Mount Sinai, join to discuss. “We still don’t know what was in that dust cloud. First came conditions like asthma and sinusitis,” said Dr. Crane. “These cancers now, this is still early for that type of condition.” - Michael Crane, MD, MPH, Assistant Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital Learn more: http://www.msnbc.com/msnbc-news/watch/security-and-health-concerns-continue-after-9- 11-762660931943

Forbes – September 11 Caring For The Other 9/11 Victims: Rescue Workers — Sharri Snelling Since 2006, Michael Crane, MD, director of the World Trade Center Health Program Clinical Center of Excellence at Mount Sinai, has been treating those workers who spent time “on the pile” clearing debris and inhaling the toxic cocktail of chemicals and particles, including asbestos, benzene, fiberglass and mercury, created when the million-ton Twin Towers collapsed into a fiery, dusty heap. “The average age of the first responders in 2001 was 38. Today, they are 53 and at an age where they have a higher risk for diseases like cancer,” said Dr. Crane. The center at Mount Sinai is one of seven Clinical Centers of Excellence treating World Trade Center rescuers and survivors. - Michael Crane, MD, MPH, Assistant Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital Learn more: http://www.forbes.com/sites/nextavenue/2016/09/11/caring-for-the-other-911-victims- rescue-workers/#267035d9416d Additional Coverage: The Daily Caller: http://dailycaller.com/2016/09/11/reports-of-911-first-responders-dying-of-cancer-are- more-complicated-than-you-think/

HealthDay Physician’s Briefing – September 9 Probable PTSD Linked to Bronchodilator Response, Asthma Probable posttraumatic stress disorder (PTSD) is associated with bronchodilator response (BDR) and incident asthma, according to a study published online in the American Journal of Respiratory and Critical care Medicine. The researchers found that probable PTSD at baseline correlated with BDR among all participants; similar results were seen for never smokers with asthma. "In a cohort of adult workers exposed to a severe traumatic event, probable PTSD is significantly associated with BDR at baseline, and predicts incident asthma," wrote Rafael E. de la Hoz, MD, MPH, an associate professor of environmental medicine and public health at the Icahn School of Medicine at Mount Sinai, and colleagues. - Rafael E. de la Hoz, MD, MPH, MSc, Associate Professor, Environmental Medicine and Public Health, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.physiciansbriefing.com/Article.asp?AID=714380 Additional Coverage: Doctor’s Lounge: http://www.doctorslounge.com/index.php/news/pb/66401

Science Daily – September 9 Researchers Identify New Therapeutic Target for Cancer New research from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai identifies a protein that may be an unexplored target to develop new cancer therapies. "New drug targets for Ras- dependent cancers have long been sought," said Arvin Dar, PhD, an assistant professor of oncological sciences at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai and lead researcher on the study. "No one has really figured out how to exploit these important drug targets. Our study opens the possibility of modulating KSR as a new cancer therapy and also potentially an entirely new class of interventions." - Arvin Dar, PhD, Assistant Professor, Oncological Sciences, Pharmacological Sciences, The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai Learn more: https://www.sciencedaily.com/releases/2016/09/160909141218.htm Additional Coverage: Politico New York Health Care: http://www.politico.com/states/new-york/tipsheets/politico-new-york- health-care/2016/09/the-other-zika-race-cuomo-moves-to-mitigate-risk-adjustment-005099 iTech Post – September 10 Brain Electric Activity May Show When Cocaine Addicts May Relapse — Rodney Rafols It has not been easy to pinpoint what causes relapses in recovering drug addicts, though a new study suggests that electric activity in the brain might have something to do with it. At the Icahn School of Medicine at Mount Sinai, research on cocaine addicts has been conducted using electroencephalography or EEG. Through its use, researchers have observed that those addicted to cocaine become vulnerable to relapse starting from the first day up to a month of abstinence. "Results of this study are alarming in that they suggest that many people struggling with drug addiction are being released from treatment programs at the time they need the most support," said Rita Goldstein, PhD, a professor of psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai. - Rita Goldstein, PhD, Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai, Chief, Brain Imaging Core, Director, Neuropsychoimaging of Addiction and Related Conditions Research Program Learn more: http://www.itechpost.com/articles/28760/20160910/brain-activity-drug-addiction- relapse.htm

HealthDay News – September 12 Dosing Errors Common With Kids' Liquid Meds — Dennis Thompson Parents may give their child too much or too little medicine when dispensing liquid medication, especially if they use a dosing cup, a new study reports. Children also might receive too little medicine to treat what ails them, said Blair Hammond, MD, assistant professor of pediatrics at the Icahn School of Medicine. "This is particularly an issue for antibiotics, where you really want them to get the correct dose of medication," Hammond said. - Blair S. Hammond, MD, Assistant Professor, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: https://consumer.healthday.com/general-health-information-16/prescription-drug-news- 551/dosing-errors-common-with-kids-meds-714737.html

Huffington Post – September 9 15 Years After 9/11, The Death Toll Continues To Rise — Linda Reinstein “The World Trade Center Health Program (WTCHP) monitors and treats over 65,000 WTC rescue/recovery workers in its Responders cohort and almost 10,000 community members in the Survivors Program,” said Michael Crane, MD, director of the World Trade Center Health Program Clinical Center of Excellence at Mount Sinai. “Forty-three percent of these workers and community members are afflicted with chronic, exposure-related conditions.” The dust that spread as the towers came down was laced with toxic substances, including ground glass, lead, gypsum, calcite, and asbestos. “These guys saved us,” said Raja Flores, MD, a professor and the chairman of thoracic surgery at the Icahn School of Medicine at Mount Sinai. “It is now our turn to save them.” - Michael Crane, MD, MPH, Assistant Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital - Raja Flores, MD, Steven and Ann Ames Professorship in Thoracic Surgery, Icahn School of Medicine at Mount Sinai, System Chair, Thoracic Surgery, Mount Sinai Health System Learn more: http://www.huffingtonpost.com/entry/fifteen-years-after-911-the-death-toll- continues_us_57d2fb21e4b0273330ac3e3f

Oncology Times – September 10 Optical Coherence Tomography for Skin Cancer — Katie Wang, DO, Amanda Levine, MD, and Orit Markowitz, MD Skin cancer is the most common malignancy worldwide, and non-melanoma skin cancers (NMSC) in particular, including basal cell carcinomas (BCC) and squamous cell carcinomas, constitute around 80 percent of all skin cancers. Over the past decade, noninvasive imaging technologies, including optical coherence tomography (OCT) and reflectance confocal microscopy (RCM), have been used in cutting- edge research and clinical settings to assist in the diagnosis and treatment of a variety of skin conditions, write Katie Wang, DO, and Amanda Levine, MD, clinical research fellows at The Mount Sinai Hospital and Orit Markowitz, MD, an assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai. - Orit Markowitz, MD, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Pigmented Lesions and Skin Cancer, Mount Sinai Dermatology Faculty Practice - Katie Wang, DO, Clinical Research Fellow, The Mount Sinai Hospital - Amanda Levine, MD, Clinical Research Fellow, The Mount Sinai Hospital Learn more: http://journals.lww.com/oncology- times/Fulltext/2016/09100/Optical_Coherence_Tomography_for_Skin_Cancer.6.aspx

The Doctors – September 12 Woman Stabbed 30 Times In The Face Forgives Attacker Julissa Marquez was brutally attacked and stabbed by her ex-boyfriend. Miraculously, she survived the horrific attack. Initially after the attack, Julissa’s doctors thought she would never see again and offered her a glass eye. But after undergoing an innovative surgery, Julissa has 30 percent of her vision in her right eye. “She had an open globe injury, and her retina was completely detached. It was crumpled up like a ball in the back of her eye.” said directed by Ronald Gentile, MD, director of the Ocular Trauma Service and surgeon director at New York Eye and Ear Infirmary of Mount Sinai. “Julissa is a remarkable person and she’s an inspiration to all of the doctors that have taken care of her.” - Ronald C. Gentile, MD, Professor, Ophthalmology, Icahn School of Medicine at Mount Sinai, Director, Ocular Trauma Service, Surgeon Director, New York Eye and Ear Infirmary of Mount Sinai Learn more: http://www.thedoctorstv.com/articles/3336-woman-stabbed-30-times-in-the-face-forgives- attacker

Women’s Health – September 5 Why Some Women Struggle With Adult Acne— Cassie Shortsleeve Turns out breaking out might not be due to poor skincare. “Our genetics determine whether we break out or not,” says Joshua Zeichner, MD, an assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai. Hormones, for example, stimulate our oil glands to rev up production of a substance called sebum, which clogs pores and feeds acne-causing bacteria, says Dr. Zeichner. - Joshua Zeichner, MD, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://www.womenshealthmag.com/beauty/why-some-women-are-more-prone-to-acne

Shape – September 9 Yoga and Acupuncture Can Relieve Back Pain, Says New Study — Cassie Shortsleeve New research suggests that acupuncture and yoga ease back pain; acupuncture and tai chi lessen the blow of osteoarthritis; and relaxation techniques keep headaches and migraines at bay. Where do the healing effects stem from? Everyone has a different theory, said Houman Danesh, MD, the director of integrative pain management at The Mount Sinai Hospital. But a few hypotheses stand out. Yoga, for one, has a lot of cross-over with physical therapy. "There's lots of flexibility and strengthening in both," he says. - Houman Danesh, MD, Assistant Professor, Anesthesiology, Rehabilitative Medicine, Icahn School of Medicine, Director, Division of Integrative Pain Management, The Mount Sinai Hospital Learn more: http://www.shape.com/lifestyle/mind-and-body/yoga-and-acupuncture-can-relieve-back- pain-says-new-study

LA Times – September 8 Dodgers Cross Fingers, Dream About October As Clayton Kershaw Returns This Weekend — Andy McCullough In July, Clayton Kershaw got the news that he had a herniated disk in his lower back. The initial disk herniation does not necessarily foretell a future of further injury, according to Andrew Hecht, MD, chief of spine surgery at the Mount Sinai Health System. Hecht said the “overwhelming majority” of athletes he treats for herniated disk avoid surgery and return to action. “Could he become symptomatic again? Well, anything is possible,” Dr. Hecht said. “But it’s a very promising thing that he’s now throwing without pain, pitching in simulated games and now getting ready to return.” - Andrew Hecht, MD, Associate Professor, Orthopaedics, Neurosurgery, Icahn School of Medicine at Mount Sinai, Chief of Spine Surgery for the Mount Sinai Health System and The Mount Sinai Hospital, Director of The Spine Hospital at Mount Sinai Learn more: http://www.latimes.com/sports/dodgers/la-sp-dodgers-kershaw-20160908-snap-story.html

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Werle, Laura Subject: Mount Sinai In the News - September 9, 2016 Date: Friday, September 09, 2016 12:38:49 PM Attachments: ATT00002.txt

In the News September 9, 2016

CBS News – September 9 9/11 Responder With Cancer — Jim Axelrod Sunday marks 15 years since the Sept. 11 attacks. Even today, the number of victims continues to rise. Among the nearly 75,000 responders and survivors health officials are monitoring, they’ve certified more than 5,400 patients with 9/11-related cancers. According to Michael Crane, MD, director of the World Trade Center Health Program Clinical Center of Excellence at Mount Sinai, that number continues to rise. “Here at Sinai, we see 10 to 15 new cancer patients in our population every week,” Dr. Crane said. “I’ve been in medicine for 40 odd years. It’s remarkable.” - Michael Crane, MD, MPH, Assistant Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital Learn more: http://www.cbsnews.com/news/september-11-attacks-anniversary-15-years-first- responders-cancer/ Additional Coverage: LA FM: http://www.lafm.com.co/internacional/noticias/investigaci%C3%B3n-relaciona-atenta-214321

Chicago Tribune – September 8 15 Years Later, 9/11 Responders Might Be Sick And Not Even Know It — Alison Brown Most of the 9/11 responders were from the New York area. But about 9,500 responders came from across the country, according to July statistics from the National Institute for Occupational Safety and Health. Some of them might not be aware that cancer or a cough could be connected to that work 15 years ago. Michael Crane, MD, director of the World Trade Center Health Program Clinical Center of Excellence at Mount Sinai, estimates 90,000 people helped in the area after the attacks. Right now, about 65,000 responders are in the WTC Health Program, run by NIOSH to track and treat them. "There's still a good chunk of folks out there who responded to the event and most likely have not been seen by anybody yet," Dr. Crane said. Mental issues are an enormous, enduring obstacle too. "These guys were really, really exposed to some horrifying sights," Dr. Crane said, adding that depression rates are similar to those of young war veterans. "It left an impact." - Michael Crane, MD, MPH, Assistant Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital Learn more: http://www.chicagotribune.com/lifestyles/health/sc-hlth-911-responder-health-20160908- story.html Additional Coverage: Next Avenue: http://www.nextavenue.org/caring-other-911-victims/

WNYC – September 9 How September 11th Revealed the Real Hillary Clinton— Andrea Bernstein and Ed Pilkington Within weeks of the September 11, 2001 attacks, Hillary Clinton had helped secure $12 million for a pilot project at Mount Sinai hospital screening some 9,000 workers with suspected Ground Zero illnesses. Philip Landrigan, MD, the dean for global health at the Icahn School of Medicine at Mount Sinai, who hosted the first World Trade Center medical program at Mount Sinai, attributes this success story mainly to Clinton’s relentless pursuit of the subject, coupled with her attention to detail. “She was angry at the Washington political leaders who would come to Ground Zero, have photos taken and then go back to DC and do nothing,” he said. “She became deeply knowledgeable on the subject, not just fiscal and administrative details, but also about medical and mental health problems.” - Philip Landrigan, MD, MSc, Professor, Environmental Medicine and Public Health, Pediatrics, Dean for Global Health, Icahn School of Medicine at Mount Sinai Learn more: http://www.wnyc.org/story/clinton-9-11/

Medscape – September 8 Asthma, PTSD, BMI Linked to GERD in 9/11 Responders — Marica Frellick Two papers published in a special September 11 edition of the American Journal of Industrial Medicine look more deeply into one of the prominent adverse effects seen among responders to and survivors of the 2001 World Trade Center (WTC) attacks: gastroesophageal reflux disease (GERD). In the first GERD study, Nikolina Icitovic, MS, a senior biostatistician in the department of environmental medicine and public health at the Icahn School of Medicine at Mount Sinai, and colleagues found an elevated risk for GERD among general responders, regardless of body mass index (BMI), compared with the general population, but also that high BMI exacerbates the risk. - Nikolina Icitovic, MS, Senior Biostatistician, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/868598

Medscape – September 8 Timing of Cocaine Relapse Pinpointed — Megan Brooks Cocaine addicts are most vulnerable to relapse between 1 and 6 months after abstinence, a time frame that coincides with the window of discharge from most addiction treatment programs. "Results of this study are alarming in that they suggest that many people struggling with drug addiction are being released from treatment programs at the time they need the most support," said principal investigator Rita Goldstein, PhD, a professor of psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai. "It's really a U-shaped trajectory that we see in these data, and these results actually replicate really well findings from animal models," said lead author Muhammad Parvaz, PhD, an assistant professor of psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai. - Rita Goldstein, PhD, Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai, Chief, Brain Imaging Core, Director, Neuropsychoimaging of Addiction and Related Conditions Research Program - Muhammad Parvaz, PhD, Assistant Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/868566

HealthDay News – September 7 Is the Pill Tied to Fewer Ovarian Cancer Deaths?— Robert Preidt Ovarian cancer deaths are down dramatically in many parts of the world, and researchers believe the use of birth control pills may be a main reason why. The analysis of World Health Organization data found that the ovarian cancer death rate fell 16 percent in the United States and almost 8 percent in Canada between 2002 and 2012. "As our understanding of preventable causes of this major cancer progresses, early detection strategies are being developed and novel therapeutic options become available, we enhance our ability to reduce ovarian cancer mortality," Paolo Boffetta, MD, the journal’s associate editor for epidemiology and director of the Institute of Translational Epidemiology at the Icahn School of Medicine at Mount Sinai, wrote in an accompanying editorial. - Paolo Boffetta, MD, MPH, Professor, Medicine, Hematology and Medical Oncology, Oncological Services, Environmental Medicine and Public Health, Associate Director, Population Sciences, Tish Cancer Institute, Chief, Division of Cancer Prevention and Control, Icahn School of Medicine at Mount Sinai Learn more: http://www.webmd.com/ovarian-cancer/news/20160907/are-birth-control-pills-tied-to- decline-in-ovarian-cancer-deaths

CNN – September 7 Analysis: Why Use Chlorine Bombs In Syria? — Tim Lister Medical groups and activists in Syria frequently allege that the Assad regime uses chlorine gas in barrel bombs against rebel-held areas. Those claims have been supported by the United Nations and international human rights groups that have studied chemical attacks in Syria. Last year, Annie Sparrow, MD, an assistant professor of environmental medicine and public health at the Icahn School of Medicine at Mount Sinai, told a congressional committee the regime's use of chlorine gas was "emblematic of its war-crime strategy." Dr. Sparrow, who spent time working in northern Syria, said: "The Assad regime has transformed a principal element of public health into a tool of disease and terror." - Annie Sparrow, MD, Assistant Professor, Environmental Medicine and Public Health, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://www.cnn.com/2016/09/07/middleeast/syria-chemical-weapons-analysis/

The Siasat Daily – September 9 Smoking During Pregnancy May Up Risk For Neuropsychiatric Disorders in Babies Women who smoke during pregnancy may increase the risk of children developing neuropsychiatric disorders associated with behavioral problems, warn researchers. The researchers found that heavy maternal smoking (10 or more cigarettes a day) during pregnancy caused a 66 per cent increase in the risk for chronic tic disorders in the child. “Our study not only shows an important role for maternal prenatal smoking in risk for both simple and complex chronic tic disorders in children, but it also suggests that smoking may be exerting some of its effects through subtle changes in brain development that might occur as a result of fetal exposure to nicotine,” said Dorothy Grice, MD, a professor of psychiatry at the Icahn School of Medicine at Mount Sinai. - Dorothy Grice, MD, Professor, Psychiatry, Icahn School of Medicine at Mount Sinai, Director, OCD and Related Disorders Clinical and Research Program, Associate Director, Tics and Tourette’s Clinical and Research Program Learn more: http://www.siasat.com/news/smoking-pregnancy-may-risk-neuropsychiatric-disorders- babies-1015937/ Additional Coverage: News-Medical: http://www.news-medical.net/news/20160907/Maternal-smoking-linked-to-increased- risk-for-Tourette-syndrome-and-tic-disorders.aspx

Medical Xpress – September 8 Risk Factors for Congenital Heart Defects May Lie Both Inside and Outside The Heart Congenital heart defects (CHDs) are a leading cause of birth defect-related deaths. Understanding how genetic alterations cause such defects is complicated by the fact that many of the critical genes are unknown, and those that are known often contribute only small increases in CHD risk. In an accompanying article, Bruce Gelb, MD, director of the Mindich Child Health and Development Institute at the Icahn School of Medicine at Mount Sinai, writes that "this work provides novel insights into incomplete penetrance and oligogenic effects underlying CHD." He adds that the novel observations "add further complexity to the way in which we need to think about CHD pathogenesis". - Bruce Gelb, MD, Professor, Pediatrics, Cardiology, Genetics and Genomic Sciences, Director, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai Learn more: http://medicalxpress.com/news/2016-09-factors-congenital-heart-defects.html

Diabetes Forecast – September 7 Winter Skin Guide— Allison Tsai Our skin acts as a buffer to the cold winter air, and while some of it may not be visible under layers of sweaters, socks, and coats, it’s still important to take good care of your largest organ. That goes double for people with diabetes. Chronic high blood glucose can up the risk of bacterial and fungal infections, said Angela Lamb, MD, an assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai. That’s why it is particularly important for people with diabetes to minimize cracks from dry skin on the hands and feet, which can open the door for harmful germs to enter the body. - Angela Lamb, MD, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Westside Mount Sinai Dermatology Faculty Practice Learn more: http://www.diabetesforecast.org/2016/sep-oct/winter-skin-guide.html? referrer=https://www.google.com/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Werle, Laura Subject: Mount Sinai In the News - September 8, 2016 Date: Thursday, September 08, 2016 12:46:23 PM Attachments: ATT00002.txt

In the News September 8, 2016

WCBS – September 7 Exposure To Toxic Dust Continues To Take Toll On 9/11 First Responders, Nearby Residents — Peter Haskell As the 15th anniversary of the 9/11 attacks approaches, the exposure to chemicals and compounds at the site is continuing to take its toll on responders and nearby residents. “We see about 10 to 15 new patients coming in with cancer every week or so,” said Michael Crane, MD, director of the World Trade Center Health Program Clinical Center of Excellence at Mount Sinai. “We now have more than 5,000 people of our 70,000 survivors and responders afflicted with cancers.” Now that Congress has fully funded the health program through the Zadroga Act, Dr. Crane said they can study the long-term effects of the exposure to the combination of polycyclic aromatic hydrocarbons, dioxins, asbestos fibers and other chemicals in the toxic dust at the site. - Michael Crane, MD, MPH, Assistant Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital Learn more: http://newyork.cbslocal.com/2016/09/07/911-health-cancer/ Additional Coverage: The Week: http://theweek.com/speedreads/647532/5441-people-have-been-diagnosed-cancer-tied-911 Raw Story: https://www.rawstory.com/2016/09/911-related-cancer-is-surging/

Reuters – September 7 Invasive Treatment Boosts Survival In Non-ST Elevation Acute Coronary Syndrome — Marilynn Larkin Early invasive treatment improves survival and postpones the occurrence of another heart attack in patients with non-ST-elevation acute coronary syndrome, according to a recent follow-up analysis of the FRISC-II trial. The study provides more "evidence that early intervention may delay the occurrence of myocardial infarction, hospitalization or death,” said Johanna Contreras, MD, MSc, an assistant professor of cardiology at the Icahn School of Medicine at Mount Sinai. “However, this effect was more significant in men and non-smokers. This suggests that an early invasive strategy may be beneficial in a selected group of patients, but not all patients, and that lifestyle modification is still paramount," she said. - Johanna Contreras, MD, Assistant Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.mdalert.com/news/article/invasive-treatment-boosts-survival-in-non-st-elevation-acute-coronary-syndrome

Science Codex – September 7 Mount Sinai Researchers Pinpoint When Cocaine-Addicted Individuals Are Most Vulnerable To Relapse New research from the Icahn School of Medicine at Mount Sinai using electroencephalography, or EEG, indicates that adults addicted to cocaine may be increasingly vulnerable to relapse from day two to one month of abstinence and most vulnerable between one and six months. "Our results are important because they identify an objectively ascertained period of high vulnerability to relapse," says Muhammad Parvaz, PhD, an assistant professor of psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai, and the study's lead author. "Unfortunately, this period of vulnerability coincides with the window of discharge from most treatment programs, perhaps increasing a person's propensity to relapse." - Muhammad Parvaz, PhD, Assistant Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://www.sciencecodex.com/mount_sinai_researchers_pinpoint_when_cocaineaddicted_individuals_are_most_vulnerable_to_relapse- 189817

Medscape – September 7 OC Use Driving Down Death Rates From Ovarian Cancer — Pam Harrison The widespread use of oral contraceptives (OCs), particularly in the United States and certain countries in the European Union, where they were introduced earlier than elsewhere, is fuelling the continued decline in death rates from ovarian cancer in many countries, a new study reveals. The findings "are important as they show how past use of hormone treatments has an impact on the mortality from ovarian cancer at the population level," commented Paolo Boffetta, MD, the Annals of Oncology associate editor for epidemiology and director of the Institute of Translational Epidemiology at the Icahn School of Medicine at Mount Sinai in New York. - Paolo Boffetta, MD, MPH, Professor, Medicine, Hematology and Medical Oncology, Oncological Services, Environmental Medicine and Public Health, Associate Director, Population Sciences, Tish Cancer Institute, Chief, Division of Cancer Prevention and Control, Icahn School of Medicine at Mount Sinai Learn more: http://www.medscape.com/viewarticle/868512

WCBS – September 7 2 New Jersey High School Football Teams Cancel Games After Several Players Contract Hand, Foot And Mouth Disease — Christine Sloan The Pequannock High School football team canceled a game against Boonton this Friday after eight members of the team came down with the coxsackievirus, better known as hand, foot and mouth disease. Gail Shust, MD, an assistant professor of infectious diseases at the Icahn School of Medicine at Mount Sinai, said the virus is very common in schools in the fall. “You can get it either from respiratory secretions from your nose, your mouth, sneezing, coughing, that sort of thing, or fecal oral—if somebody doesn’t wash their hands well after using the bathroom, things like that,” explained Dr. Shust. - Gail Shust, MD, Assistant Professor, Pediatrics, Infectious Diseases, Medical Education, Icahn School of Medicine at Mount Sinai Learn more: http://newyork.cbslocal.com/2016/09/07/new-jersey-school-coxsacievirus/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Werle, Laura Subject: Mount Sinai In the News - September 7, 2016 Date: Wednesday, September 07, 2016 1:13:37 PM Attachments: ATT00002.txt

In the News September 7, 2016

Newsweek – September 7 9/11’s Second Wave: Cancer and Other Diseases Linked To The 2001 Attacks Are Surging — Leah McGrath Goodman Days after the attacks, rescue workers started showing up at Mount Sinai Hospital in New York for treatment and medical assistance. Many of them had injuries and respiratory problems from the debris that had fallen on them. “The symptoms these patients have are terrifying,” says Michael Crane, MD, director of the World Trade Center Health Program Clinical Center of Excellence at Mount Sinai, which treats around 22,000 rescue and recovery workers. “They will suddenly wake up and find they cannot breathe.” The average age of rescue and recovery workers is approaching 54, says Andy Todd, co- deputy director of the World Trade Center Health Program. More than half are suffering from multiple World Trade Center–related illnesses. Today, 15 years after the attacks, doctors are starting to understand why people are still dying. - Michael Crane, MD, MPH, Assistant Professor, Preventive Medicine, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital - Andy Todd, PhD, Research Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Co-Deputy Director of Mount Sinai’s World Trade Center Health Program Learn more: http://www.newsweek.com/2016/09/16/9-11-death-toll-rising-496214.html Additional Coverage: Healthline: http://www.healthline.com/health-news/nearly-40000-have-health-conditions-related-to-9- 11#1

Healthcare Business Daily News – September 6 Mount Sinai Beth Israel Orthopaedics awarded Advanced Certification for Hip and Knee by The Joint Commission Mount Sinai Beth Israel has earned The Joint Commission’s Gold Seal of Approval for Advanced Certification for Total Hip and Total Knee Replacement. It is the only hospital in New York City to receive the prestigious certification for an orthopedic program. “This Advanced Certification means we have set the standard for best orthopedic practices in the country,” said Steven Harwin, MD, the chief of adult reconstruction and total joint replacement at Mount Sinai Beth Israel. “The Joint Commission recognizes the outstanding quality of care provided by our entire team of caregivers, from nurses in the operating room to physical therapists, internists, and orthopedic surgeons,” said Peter McCann, MD, chair of the department of orthopaedic surgery at Mount Sinai Beth Israel. “This achievement points out the quality and exceptional orthopedic care at Mount Sinai Beth Israel,” said Leesa Galatz, MD, system chair of orthopaedics at Mount Sinai Health System. “We are excited to receive this prestigious certification from The Joint Commission that sets us apart from orthopedic departments across the country,” said Susan Somerville, RN, President of Mount Sinai Beth Israel. - Susan Somerville, RN, President, Mount Sinai Beth Israel - Leesa Galatz, MD, Professor, Leni and Peter W. May Department of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, System Chair, Orthopaedics, Mount Sinai Health System - Steven Harwin, MD, Professor, Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, Chief, Adult Reconstruction and Total Joint Replacement, Mount Sinai Beth Israel - Peter McCann, MD, Professor, Orthopaedics, Icahn School of Medicine at Mount Sinai, Chair, Department of Orthopaedic Surgery, Mount Sinai Beth Israel Learn more: https://www.dotmed.com/news/story/32780

Becker’s Hospital Review – September 6 Not Your Usual Hospital Ad: 'If Our Beds Are Filled, It Means We've Failed' — Kelly Gooch Rather than focusing on a surgical specialty, new robotic device or national ranking, some health systems are taking out ad space to get patients and consumers in on their population health strategy. Mount Sinai Health System's population health advertising campaign began when the organization launched a print ad campaign designed to showcase its impact on New York City neighborhoods, contributions to research and education and collaborations in local and global communities. "The two themes of the campaign were, 'We're a different sort of system. We're in your community. We're accessible' and 'We're focused on health and wellness,'" said Niyum Gandhi, chief population health officer for the Mount Sinai Health System. "Some people might look at that and say, 'You don't care about the cutting-edge medicine. You don't care about the high-acuity care. But that's not true. We're just saying we care about something else also.” - Niyum Gandhi, Chief Population Health Officer, Mount Sinai Health System Learn more: http://www.beckershospitalreview.com/hospital-management-administration/not-your- usual-hospital-ad-if-our-beds-are-filled-it-means-we-ve-failed.html

Forbes – September 6 New Clues Into How Meditation May Boost The Immune System — Alice Walton In a new study, a team of researchers from the Icahn School of Medicine at Mount Sinai, University of California at San Francisco, and Harvard Medical School had 94 women come to the Chopra Center for Well Being in California. The team took blood samples from the participants, so they could analyze what genes were expressed, before the retreat, directly after it, one month, and 10 months later. And there were some interesting changes in the 20,000 genes studied. All the groups showed shifts in the expression of genes related to stress, inflammation and wound healing. - Icahn School of Medicine at Mount Sinai Learn more: http://www.forbes.com/sites/alicegwalton/2016/09/06/new-clues-into-how-meditation-can- boost-the-immune-system/#5b19b1901c18

Metro New York – September 7 Ask Mount Sinai: Why Vaccines Are Important — Sheila Dougherty All children ages 2 through 18 attending daycare or school in New York City (and state) are required to have been immunized against contagious diseases such as measles, mumps, rubella and chickenpox. And starting this year, seventh graders in New York state are required to be vaccinated against meningitis. Gail Shust, MD, an assistant professor in pediatrics and infectious diseases at the Icahn School of Medicine at Mount Sinai explains the importance of vaccinations. - Gail Shust, MD, Assistant Professor, Pediatrics, Infectious Diseases, Medical Education, Icahn School of Medicine at Mount Sinai Learn more: http://www.metro.us/lifestyle/ask-mt-sinai-why-vaccines-are-important/zsJpif--- coOJCUh6VKDDo/

Optics and Photonics News – September 5 Advanced OCT: Making Waves in the Market — Valerie Coffey Optical coherence tomography is poised for further growth thanks to a new wave of progress in applications with commercial potential. Here’s a cross-sectional survey of OCT advances making their way from concept to market. “What is exciting about the new speckle-variance feature is its potential to help better differentiate non-melanoma skin cancer,” said Orit Markowitz, MD, an assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai. “It can also help differentiate between melanoma and dysplastic nevi.” Dr. Markowitz and her team are putting together a large “atlas” to help dermatologists differentiate the numerous types of pigmented lesions. - Orit Markowitz, MD, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Pigmented Lesions and Skin Cancer, Mount Sinai Dermatology Faculty Practice Learn more: http://www.osa- opn.org/home/articles/volume_27/september_2016/features/advanced_oct_making_waves_in_the_market/

Fertility Authority – September 5 What are Treatments, Including Lifestyle Modifications, for Male Infertility? Natan Bar-Chama, MD, director of male reproductive medicine and surgery at The Mount Sinai Hospital, discusses the different treatments and lifestyle modifications that can help male infertility. “We know that men who are overweight have decreased fertility, so I think the first step is lifestyle. What can we do to improve your semen parameters by adhering to a healthy lifestyle?” Dr. Bar-Chama said. - Natan Bar-Chama, MD, Associate Professor, Urology, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Male Reproductive Medicine and Surgery, The Mount Sinai Hospital Learn more: https://www.fertilityauthority.com/video/what-are-treatments-including-lifestyle- modifications-male-infertility

Vocativ – September 6 Ovarian Cancer Deaths Plummet, Thanks To The Pill — Joshua Krisch A new study in Annals of Oncology suggests that ovarian cancer deaths are plummeting across Europe, due to more uniform use of oral contraceptives. “The findings of Professor La Vecchia and his colleagues are important as they show how past use of hormone treatments has an impact on the mortality from ovarian cancer at the population level,” said Paolo Boffetta, MD, MPH, chief of the Division of Cancer Prevention and Control at the Icahn School of Medicine at Mount Sinai. “As our understanding of preventable causes of this major cancer progresses, early detection strategies are being developed and novel therapeutic options become available, we enhance our ability to reduce ovarian cancer mortality.” - Paolo Boffetta, MD, MPH, Professor, Medicine, Hematology and Medical Oncology, Oncological Services, Environmental Medicine and Public Health, Associate Director, Population Sciences, Tish Cancer Institute, Chief, Division of Cancer Prevention and Control, Icahn School of Medicine at Mount Sinai Learn more: http://www.vocativ.com/356473/ovarian-cancer-pill/ Additional Coverage: Science Daily: https://www.sciencedaily.com/releases/2016/09/160906085007.htm

Graphic Online – September 6 Health Workers Trained In Early Detection of Cancer — Gracious Akande Linus Chuang, MD, a professor of gynecology and reproductive science at the Icahn School of Medicine at Mount Sinai, has said cervical cancer can be eradicated through regular screening and vaccination. He has advocated that young girls be vaccinated and all females in Ghana be regularly screened to prevent them from developing cervical cancer. The two-day workshop, held in Accra, was organized by the Ghana Health Service to equip healthcare providers with the necessary knowledge for the early detection of breast and cervical cancers, which is the major challenge health workers face in dealing with cancer cases in the country. - Linus Chuang, MD, Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Fellowship Director, Minimally Invasive Surgery in Gynecology Learn more: http://www.graphic.com.gh/news/general-news/health-workers-trained-in-early-detection- of-cancer.html

Orthopedics This Week – September 6 Advanced Workstations Guiding US Open Physicians — Elizabeth Hofheinz The high-level athletes at the US Open for the first time have available onsite advanced image-viewing workstations that can guide physicians in making a rapid diagnosis. For the fourth year in a row, Mount Sinai Hospital is the official medical services provider for the tournament. “This is one of the few major tennis events in the world that has full-time radiologists on site to provide these specific services,” said Carlos L. Benitez, MD, director of musculoskeletal imaging at Mount Sinai West and Mount Sinai St. Luke's. “Our physicians look forward to refining unique skills required to care for professional athletes at the US Open, and using this knowledge to better treat our year-round patients who participate in athletics,” said James Gladstone, MD, co-chief of the sports medicine service at The Mount Sinai Hospital. Alexis Colvin, MD, an associate professor of orthopaedic surgery at the Icahn School of Medicine at Mount Sinai, is the team physician for the US Fed Cup Team. - Carlos Benitez, MD, Assistant Professor, Radiology, Icahn School of Medicine at Mount Sinai, Director, Musculoskeletal Imaging, Mount Sinai West and Mount Sinai St. Luke’s - James Gladstone, MD, Associate Professor, Orthopaedics, Sports Medicine Service, Icahn School of Medicine at Mount Sinai, Co-Chief, Sports Medicine, The Mount Sinai Hospital - Alexis Colvin, MD, Associate Professor, Orthopaedics, Sports Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://ryortho.com/breaking/advanced-workstations-guiding-us-open-physicians/

Web MD – September 6 Disk Fixes for Lower Back Pain — Barbara Brody About 80% of Americans have low back pain at some point. It’s usually short-lived, but if yours lingers for weeks or months, you may wonder if surgery would help. Low back pain has many causes. Often it's linked to one or more of the rubbery disks that normally cushion the vertebrae in your spine. "Your disks have an outer hard shell and a soft jelly inside, and if you develop a little tear, the jelly-like material can start to push its way out and hit a nerve," says Sheeraz Qureshi, MD, an associate professor of orthopaedics at the Icahn School of Medicine at Mount Sinai. - Sheeraz Qureshi, MD, Associate Professor, Orthopaedics, Icahn School of Medicine at Mount Sinai, Associate Director, Mount Sinai Spine Center, Chief, Minimally Invasive Spine Surgery, Icahn School of Medicine at Mount Sinai Learn more: http://www.webmd.com/back-pain/features/spinal-disk-surgeries

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Slotnick, David Subject: Mount Sinai In The News - September 6, 2016 Date: Tuesday, September 06, 2016 1:08:15 PM Attachments: ATT00002.txt

In the News September 6, 2016

New York Daily News – September 2 Little Girl Born Deaf in Afghanistan Hears Sound For The First Time After Mount Sinai's Generous Surgery — Mary McDonnell Reuven Blau and Lisa L. Colangelo A 2-year-old girl who loves to dance, despite being deaf since birth, can now hear the music thanks to life-altering surgery she received as a gift from a Manhattan hospital. Nehal Farid, who was born in Afghanistan, underwent surgery last month at the New York Eye and Ear Infirmary of Mount Sinai to place a cochlear implant in her right ear. The hospital waived the cost of the Aug. 9 surgery. And the implant, which costs about $25,000, was donated by Cochlear Americas, which builds the devices. “She’s one of the brightest and most intelligent little girls that I’ve met,” said Dr. Peter Weber, 54, who performed the surgery. “The prognosis long-term is she should do great. She’ll catch up.” - Peter Weber, MD, MBA, Professor, Otolaryngology, Icahn School of Medicine at Mount Sinai, Director, Ear Institute, New York Eye and Ear Infirmary of Mount Sinai Learn more: http://www.nydailynews.com/new-york/afghani-girl-born-deaf-hears-sound-time-article- 1.2776159 Additional Coverage: New York Daily News: http://www.nydailynews.com/new-york/afghani-girl-2-cochlear-implant- turned-great-article-1.2777165 WCBS: http://newyork.cbslocal.com/2016/09/02/afghan-girl-hears-for-first-time/

Crain’s Health Pulse – September 6 Mount Sinai West to Add Surgical Capacity — Jonathan LaMantia As part of the Mount Sinai Health System's effort to reconfigure its service lines around centers of excellence, Mount Sinai West is pursuing plans to boost its surgical capacity. The Manhattan hospital has proposed a $14.3 million renovation that would relocate endoscopy services within its campus and reduce the number of rooms dedicated to the procedure from four to three. To support the additional surgical space, it will double the number of stations in its post-anesthesia care unit to 32 and create a prep/recovery space with 18 patient rooms. The construction will take place over several phases, the hospital said in its certificate-of-need application. Mount Sinai West will take on more of the health system's surgical cases "in light of the ongoing transformation of services at each of its facilities, as well as the large and growing surgical volume at its facilities," the application said. - Mount Sinai West Learn more: http://www.crainsnewyork.com/article/20160906/PULSE/160909964/new-york- presbyterians-new-mission-control-centers-lower-wait-times

Crain’s Health Pulse – September 6 Who’s News René S. Kahn, MD, has been appointed chair of the Department of Psychiatry at the Icahn School of Medicine at Mount Sinai and will start on Jan. 1. Dr. Kahn is currently a professor of psychiatry and director of the Brain Center Rudolf Magnus at the University Medical Center Utrecht in the Netherlands. - Rene S. Kahn, MD, Adjunct Associate Professor, Psychiatry, Chair, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, Learn more: http://www.crainsnewyork.com/article/20160906/PULSE/160909964/new-york- presbyterians-new-mission-control-centers-lower-wait-times

Reuters – September 2 Adult-Onset Asthma Tied to Higher Risk Of Heart Attack, Stroke and Other CVD — Marilynn Larkin An asthma diagnosis at age 18 or older is associated with an increased risk of heart attack, stroke or other cardiovascular disease (CVD)-related events, researchers say. "This was a prospective study and confounding factors were well controlled,” said Allan Stewart, MD, the director of aortic surgery at The Mount Sinai Hospital. "Although the mechanism for the association was beyond the scope of this investigation, there is a useful message in this conclusion," he noted, "because patients with adult-onset asthma, and equally importantly, the treating physician, may attribute any increase in respiratory symptoms to asthma and not pick up a cardiac event." - Allan Stewart, MD, Associate Professor, Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai, Director, Aortic Surgery, Co-Director, Valve Repair Center, The Mount Sinai Hospital Learn more: http://www.mdalert.com/news/article/adult-onset-asthma-tied-to-higher-risk-of-heart- attack-stroke-and-other-cvd-events

The Science Explorer – September 2 Why do some Children of Holocaust Survivors Show Signs of Trauma? Epigenetics could be the Answer Animal studies have demonstrated that epigenetic changes from stress exposure can be passed on to the offspring. In the new study, Rachel Yehuda, PhD, director of the Traumatic Stress Studies Division at the Icahn School of Medicine at Mount Sinai, and colleagues examine these relationships for the first time in humans, with methylation of FKBP5, a stress-related gene that has been associated with PTSD and depression. The analysis revealed that both Holocaust survivors and their offspring show epigenetic changes at the same site of FKBP5 intron 7, but in the opposite direction; Holocaust survivors had 10% higher methylation than control parents, whereas Holocaust offspring had 7.7% lower methylation than control offspring. "These observations suggest that parental trauma is a relevant contributor to offspring biology," said Dr. Yehuda. - Rachel Yehuda, PhD, Professor, Psychiatry, Neuroscience, Director, Traumatic Stress Studies Division, Icahn School of Medicine at Mount Sinai Learn more: http://thescienceexplorer.com/humanity/why-do-some-children-holocaust-survivors-show- signs-trauma-epigenetics-could-be-answer

Bel Marra Health – September 2 Reversing Impaired Kidney Function In Diabetics May Be Possible With Ketogenic Diet — Devon Andre Reversing impaired kidney function in diabetics may be possible with the ketogenic diet. The researchers at the Icahn School of Medicine at Mount Sinai found that the ketogenic diet, a style of eating based on high-fat and low-carbohydrate intake, may be beneficial in reversing kidney function. “Our study is the first to show that a dietary intervention alone is enough to reverse this serious complication of diabetes,” said Charles Mobbs, PhD, a professor of endocrinology, diabetes and bone disease at the Icahn School of Medicine at Mount Sinai. “This finding has significant implications for the tens of thousands of Americans diagnosed with diabetic kidney failure, and possibly other complications, each year.” - Charles Mobbs, PhD, Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Geriatrics and Palliative Medicine, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: http://www.belmarrahealth.com/reversing-impaired-kidney-function-diabetics-may- possible-ketogenic-diet/

Web MD – September 2 Fried, Grilled or Baked Foods? They May Affect Type 2 Diabetes Risk — Serena Gordon Changing the way you cook could help reduce your risk of getting type 2 diabetes, a new study suggests. When you fry, grill or bake foods -- also called dry-heat cooking—foods produce substances called advanced glycation end products (AGEs). Higher levels of AGEs have been linked to insulin resistance, stress on the body's cells and inflammation, according to the study authors. These are troublemakers in terms of diabetes risk. "When you look at people with chronic diseases like type 2 diabetes or dementia put on a high-AGE diet or a low one, those on the low-AGE diet show signs of decreasing inflammation," said the study's lead author, Jaime Uribarri, MD, a professor of medicine at the Icahn School of Medicine at Mount Sinai. - Jaime Uribarri, MD, Professor, Medicine, Nephrology, Icahn School of Medicine at Mount Sinai Learn more: http://www.webmd.com/diabetes/news/20160902/fried-grilled-or-baked-foods-they-may- affect-type-2-diabetes-risk Additional Coverage: Tech Times: http://www.techtimes.com/articles/176254/20160904/how-you-cook-meals-can-affect-your- risk-for-type-2-diabetes-study.htm

American Pharmacists Association – September 2 Why It's Bad To Skip Prescribed Drugs After A Heart Attack Heart attack survivors fail to follow their medication regimens, researchers find, even though doing so can protect them from another cardio-related event or death. A team from Mount Sinai Heart gauged adherence to statins for more than 4,000 people recovering from heart attack and adherence to ACE inhibitors for nearly 13,000 people suffering from clogged arteries - Mount Sinai Heart Learn more: http://www.pharmacist.com/why-its-bad-skip-prescribed-drugs-after-heart-attack

Time Warner Cable News – September 5 Fifteen Years after the Towers Fell, Doctors Still Trying to Understand the Full Health Impact of the Attacks — Erin Billups Fifteen years after the September 11 attacks researchers are still trying to understand the full impact of the toxins that were created when the towers fell. In recent months, the World Trade Center Health Program Clinical Center of Excellence at The Mount Sinai Hospital has seen 30 to 40 responders walking in for treatment each week—for the first time. "They had a very, very difficult mixed exposure of really awful stuff and I think now we're beginning to see the consequences of that," said Michael Crane, MD, director of the program. Dr. Crane says exposure to the cocktail of toxins has made some of these cancers more difficult to treat. "It wasn't just one substance, it wasn't just asbestos fibers, it wasn't just aromatic hydrocarbons, it was a whole gimmish of everything going right into people's lungs," Dr. Crane said. - Michael Crane, MD, MPH, Assistant Professor, Preventive Medicine, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital Learn more: http://www.ny1.com/nyc/all-boroughs/911-fifteenth-anniversary/2016/09/5/fifteen-years- after-the-towers-fell--doctors-still-trying-to-understand-the-full-health-impact-of-the-attacks.html

Genome Magazine – September Determining a Drug Response — Sonya Collins Researchers have the data to predict how people might respond to certain drugs. But healthcare system infrastructure lags far behind science in its ability to put pharmacogenomics into practice. Relatively few hospitals use pharmacogenomic testing today. Some estimates say it is fewer than 10 percent. “To actually get reimbursed for a genetic test for pharmacogenetics, there have to be very specific indications for doing that test. That’s a real challenge,” said Stuart Scott, PhD, an assistant professor of genetics and genomic sciences at the Icahn School of Medicine at Mount Sinai. Dr. Scott’s research includes clinical implementation of genetic testing and personalized medicine. - Stuart Scott, PhD, Assistant Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai Learn more: http://genomemag.com/pharmacogenomics/#.V87gRksrIdX

Healio’s HemOnc Today – September 2 Choice Between Lumpectomy, Mastectomy Requires Patient-Provider Collaboration — Ryan McDonald The decision to undergo either a mastectomy or a lumpectomy is an incredibly personal decision that the majority of patients with breast cancer will have to face during treatment, Susan Boolbol, MD, chief of the division of breast surgery at Mount Sinai Beth Israel, told HemOnc Today. “The reality is – and it’s really good – that in our country, most breast cancers are diagnosed early – meaning smaller – and patients do have the option between a lumpectomy and a mastectomy,” she said. The positive, Boolbol mentions, is that the type of surgery does not impact overall survival rates. Instead, survival is dictated on the biology of the cancer and the course of the disease. - Susan Boolbol, MD, Associate Professor, Surgery, Icahn School of Medicine at Mount Sinai, Chief, Breast Surgery, Mount Sinai Beth Israel Learn more: http://www.healio.com/hematology-oncology/breast-cancer/news/online/%7Bac8f162a- 8cdc-490e-b030-41e4ce6a5c17%7D/choice-between-lumpectomy-mastectomy-requires-patient-provider- collaboration

Fox News – September 1 Program Helps Families 'Adopt' Embryos Donated By Other Couples — Lindsay Carlton When IVF couples finish their family building, "extra" embryos can be terminated, frozen indefinitely, given to science for research or donated for reproduction. Programs allow potential parents to adopt the frozen embryos. Joseph Davis, DO, a reproductive endocrinologist and infertility specialist at The Mount Sinai Hospital, said transferring an embryo is an office-based procedure that typically takes a few minutes. “We place a speculum much like a pap smear and through a very small catheter or straw are able to transfer a single embryo into the uterus under guidance of an ultrasound,” Dr. Davis. - Joseph B. Davis, DO, Reproductive Endocrinologist and Infertility Specialist, Reproductive Medicine, Division of Reproductive Endocrinology and Infertility, The Mount Sinai Hospital Learn more: http://www.foxnews.com/health/2016/09/01/program-helps-families-adopt-embryos- donated-by-other-couples.html

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Werle, Laura Subject: Mount Sinai In the News - September 2, 2016 Date: Friday, September 02, 2016 12:49:01 PM Attachments: ATT00003.txt

In the News September 2, 2016

Becker’s Hospital Review – September 1 32 CMIOs to Know The role of the CMIO is gaining importance in healthcare as hospitals and health systems seek to marry clinical processes with information systems. Health IT is emerging as a priority for many healthcare providers, largely bolstered by federal initiatives and a push toward interoperability and data exchanges. Bruce Darrow, MD, PhD, an associate professor of cardiology at the Icahn School of Medicine at Mount Sinai, has been the CMIO for the Mount Sinai Health System since February 2012. Dr. Darrow is board certified in clinical informatics by the American Board of Preventive Medicine. - Bruce Darrow, MD, PhD, Associate Professor, Medicine, Cardiology, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Chief Medical Officer, Vice President of Information Technology, Mount Sinai Health System Learn more: http://www.beckershospitalreview.com/lists/32-cmios-to-know.html

Becker’s Health IT and CIO Review – September 1 Innovative New Contact Lenses Dispense Medication While Worn — Alyssa Rege Researchers have created a new type of contact lens capable of delivering medication to an individual's eyes while worn. Janet B. Serle, MD, a professor of ophthalmology at Icahn School of Medicine at Mount Sinai, said the lenses are more convenient for some patients and ensure patients receive the appropriate amount of medication with each dose. - Janet B. Serle, MD, Professor, Ophthalmology, Icahn School of Medicine at Mount Sinai, Director, Glaucoma Clinical Fellowship, Glaucoma Research Fellowship Learn more: http://www.beckershospitalreview.com/healthcare-information-technology/innovative- new-contact-lenses-dispense-medication-while-worn.html

Web MD – September 1 New Version of RA Drug Enbrel: FAQ —Jennifer Clopton The FDA cleared the way for what is hoped may be a more affordable version of the popular arthritis drug Enbrel. The FDA says the two medications work the same way and are both safe and effective. “A biosimilar is almost identical in structure to the parent drug and there should not be any problem taking it, although long-term safety data is lacking,” said Yousaf Ali, MBBS, chief of rheumatology at Mount Sinai West. - Yousaf Ali, MBBS, Associate Professor, Medicine, Rheumatology, Icahn School of Medicine at Mount Sinai, Chief of Rheumatology, Mount Sinai West Learn more: http://www.webmd.com/rheumatoid-arthritis/news/20160901/erelzi-biosimilar-enbrel- arthritis-faq

Photonics Media – September 2 Virtual Reality May Offer Advances in Microscope Imaging A novel microscope image injection system has demonstrated the ability to relay virtual reality imaging to a surgeon through an eyepiece, known as the ocular, during microscopic surgery. "This next- generation augmented virtual reality tool provides real-time information in ways never before realized," said Joshua Bederson, MD, chairman of neurosurgery for Mount Sinai Health System. "We are driving and advancing the development of next-generation simulation and virtual reality technology, which can help improve patient outcomes and solve neurosurgical challenges.” - Joshua Bederson, MD, Professor, Neurosurgery, Icahn School of Medicine at Mount Sinai, System Chair, Neurosurgery, Mount Sinai Health System Learn more: http://www.photonics.com/Article.aspx?AID=61071

Time – September 1 Why You Need to Start Meditating on Vacations — Kerry Close It’s good for the mind, body, and soul to escape with some relaxation on the beach. But you might want to consider meditating while you’re away to give yourself even more of a healthy boost. Vacationers who meditate while on vacation may be less inclined toward depression and stress, according to new research from scientists from the Icahn School of Medicine at Mount Sinai; the University of California, San Francisco; and Harvard Medical School. - Icahn School of Medicine at Mount Sinai Learn more: http://time.com/money/4475742/vacation-meditation-benefits-study/ Additional Coverage: Huffington Post: http://www.huffingtonpost.ca/2016/09/01/meditation-retreat_n_11817520.html GEN: http://www.genengnews.com/gen-news-highlights/vacation-and-meditation-impact-stress- response-and-immune-function-related-gene-activity/81253151/

Health – August 31 Here’s What Happens to Your Body During an Aerial Yoga Class — Kathleen Mulpeter While yoga in general offers a slew of health benefits, does aerial yoga provide its own unique perks? To find out whether hanging upside down is especially good for you, I called Allan Stewart, MD, the director of aortic surgery at The Mount Sinai Hospital. If you suffer from back spasms, scoliosis, or a herniated disc, hanging upside down may ease painful symptoms. "It can lengthen your ligaments, and at least temporarily relax your muscles," Dr. Stewart explains. - Allen Stewart, MD, Associate Professor, Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai, Director, Aortic Surgery, Co-Director, Valve Repair Center, The Mount Sinai Hospital Learn more: http://www.health.com/fitness/aerial-yoga-health-benefits

HealthDay News – September 2 Fried, Grilled or Baked Foods? They May Affect Type 2 Diabetes Risk — Serena Gordon Changing the way you cook could help reduce your risk of getting type 2 diabetes, a new study suggests. When you fry, grill or bake foods -- also called dry-heat cooking—foods produce substances called advanced glycation end products (AGEs). Higher levels of AGEs have been linked to insulin resistance, stress on the body's cells and inflammation, according to the study authors. These are troublemakers in terms of diabetes risk. "When you look at people with chronic diseases like type 2 diabetes or dementia put on a high-AGE diet or a low one, those on the low-AGE diet show signs of decreasing inflammation," said the study's lead author, Jaime Uribarri, MD, a professor of medicine at the Icahn School of Medicine at Mount Sinai. - Jaime Uribarri, MD, Professor, Medicine, Nephrology, Icahn School of Medicine at Mount Sinai Learn more: https://consumer.healthday.com/diabetes-information-10/type-ii-diabetes-news- 183/cooking-with-water-may-alter-type-2-diabetes-risk-714457.html

TCT MD September 1 Short-term DAPT Not Necessarily the Best Option for All, Especially After Complex PCI — Yael Maxwel Much of the conversation around individualizing decisions on dual antiplatelet therapy (DAPT) duration after PCI has focused on clinical parameters, but a new study presented Monday at the European Society of Cardiology (ESC) Congress 2016 advocates integrating anatomical factors in order to more precisely prevent adverse outcomes. However, Gennaro Giustino, MD, a postdoctoral fellow in interventional cardiology at the Icahn School of Medicine at Mount Sinai, and colleagues used a different methodology to evaluate the efficacy and safety of short-term (3 or 6 months) or long-term (at least 12 months) dual antiplatelet therapy after PCI. The results released at the ESC Congress were simultaneously published online in the Journal of the American College of Cardiology. - Gennaro Giustino, MD, Postdoctoral Clinical Research Fellow, Interventional Cardiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.tctmd.com/show.aspx?id=136146

Genetic Engineering and Biotechnology News – September 1 Pharmacogenetics Informs Clinical Practice — DeeAnn Visk Technical hurdles to the wide-spread use of genetic data in humans are disappearing. The cost of sequencing an entire human genome is sinking to around $1,000. Institutions are working on integrating genetic data with their EHRs. “Normally, pharmacogenetic testing is done after the fact,” said Stuart Scott, PhD, an assistant professor of genetics and genomic sciences at the Icahn School of Medicine at Mount Sinai. “We see this as less helpful for patients and advocate doing pharmacogenetic testing beforehand—preemptively.” At Mount Sinai, Dr. Scott is participating in programs that preemptively test patients for genes involved in drug response variability. Patient-specific gene-drug information is added to the patient’s EHR, where it sits until the doctor orders a drug for which there is pertinent genetic information. - Stuart Scott, PhD, Assistant Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai Learn more: http://www.genengnews.com/gen-articles/pharmacogenetics-informs-clinical-practice/5816/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200

From: ITNDaily on behalf of Slotnick, David Subject: Mount Sinai In The News - September 1, 2016 Date: Thursday, September 01, 2016 1:25:17 PM Attachments: ATT00002.txt

In the News September 01, 2016

US News & World Report – August 31 Get Set for the Modern House Call— Beth Howard When Tiana Thomas went to The Mount Sinai Hospital emergency room last winter with an infection in her transplanted right kidney, she expected to be admitted for a round of high-potency intravenous antibiotics. Over the next 10 days, while she prepared her own meals and worked from home, nurses dropped by to administer the antibiotic infusion and check her vital signs, and a doctor visited via video. She was “discharged” having never left home. That’s the underlying philosophy of Hospital at Home, a novel health delivery model that is being tested at Mount Sinai and other hospitals nationwide. - The Mount Sinai Hospital Learn more: http://www.usnews.com/news/articles/2016-08-31/get-set-for-the-modern-house-call

Leadership – July 28 Collaborating Around Bundled Payments— Lola Butcher Recently, the Mount Sinai Health System worked out the care redesign needed to succeed with joint replacements in the Bundled Payments for Care Improvement program—and used that as a launching pad for a bundled payment contract with a single purchaser. "This is really taking it to completely another level that goes beyond just a payment model or a clinical model," says Niyum Gandhi, Mount Sinai’s chief population health officer. "It's actually a holistic member experience, which we couldn't have done without the complementary set of insights on what the member needs." - Niyum Gandhi, Chief Population Health Officer, Mount Sinai Health System Learn more: http://www.hfma.org/Leadership/Archives/2016/Summer/Collaborating_Around_Bundled_Payments/

News-Medical – September 1 Epigenetic Changes From Stress Exposure Can Be Passed From Traumatize Parent To Offspring The children of traumatized people have long been known to be at increased risk for posttraumatic stress disorder (PTSD), and mood and anxiety disorders. However, according to Rachel Yehuda, PhD, director of the Traumatic Stress Studies Division at the Icahn School of Medicine at Mount Sinai, who led a new study in Biological Psychiatry, there are very few opportunities to examine biologic alterations in the context of a watershed trauma in exposed people and their adult children born after the event. - Rachel Yehuda, PhD, Professor, Psychiatry, Neuroscience, Director, Traumatic Stress Studies Division, Icahn School of Medicine at Mount Sinai Learn more: http://www.news-medical.net/news/20160901/Epigenetic-changes-from-stress-exposure- can-be-passed-from-traumatized-parent-to-offspring.aspx

Crain’s Health Pulse – September 1 Mount Sinai Doubles Profits The Mount Sinai Hospital reported a $66.2 million operating profit through the first half of 2016, more than double its income from the same period a year earlier. Operating revenue rose 9.8% to $1.13 billion, as outpatient volume grew in cancer and non-cancer infusion, radiation oncology and ambulatory surgery cases, according to unaudited financial statements. - The Mount Sinai Hospital Learn more: http://www.crainsnewyork.com/article/20160901/PULSE/160909998/health-care-union-says- nyu-langone-is-plotting-to-cut-benefits

Good Magazine – September 1 Why You Absolutely Can’t Work This Labor Day Weekend — Kate Ryan According to a study published in Springer Nature's journal Translational Psychiatry earlier this week, vacations and meditation are quantifiably good for you. Scientists from the Icahn School of Medicine at Mount Sinai who were involved with the study, discovered that a resort vacation provides a strong and immediate impact on molecular networks associated with stress and immune pathways, in addition to short-term improvements in well-being, as measured by feelings of vitality and distress. - Icahn School of Medicine at Mount Sinai Learn more: https://www.good.is/articles/vacation-health-benefits-study

Lexington Herald Leader – August 31 These Futuristic Contact Lenses Dispense Drugs While You Wear Them— Ariana Eunjung Cha Researchers have come up with a new type of contact lens system that gradually delivers medication to your eye while you wear them. The research was conducted using latanoprost, a medication for glaucoma, and looked at how the contact lenses performed versus traditional daily eye drops. Janet B. Serle, MD, a professor of ophthalmology at Icahn School of Medicine at Mount Sinai explained that the new contact lens removes the burden of administration from the patient and ensures consistent delivery of medication to the eye, eliminating the ongoing concern of patient compliance with dosing. - Janet B. Serle, MD, Professor, Ophthalmology, Icahn School of Medicine at Mount Sinai, Director, Glaucoma Clinical Fellowship, Glaucoma Research Fellowship Learn more: http://www.kentucky.com/living/health-and-medicine/article99076812.html

Neurology Advisor – August 31 Nicotine Exposure During Pregnancy Linked to Tourette Syndrome in Children — Dinko Kranjac In a recent study, a team of investigators affiliated with the Icahn School of Medicine at Mount Sinai and Aarhus University, Denmark, identified more than 90 000 pregnancies from The Danish National Birth Cohort study with detailed information on lifestyle and health behaviors. This was done in order to examine the role of prenatal maternal smoking in risk for Tourette Syndrome and chronic tic disorder (TS/CT) and pediatric-onset obsessive-compulsive disorder (OCD), as well as in risk for TS/CT with comorbid ADHD or other comorbid, severe psychiatric diagnoses. - Icahn School of Medicine at Mount Sinai Learn more: http://www.neurologyadvisor.com/movement-disorders/nicotine-exposure-during- pregnancy-linked-to-tourette-syndrome-in-children/article/519775/

If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200