From: ITNDaily Subject: Mount Sinai In The News - June 1, 2018 Date: Friday, June 01, 2018 1:51:23 PM Attachments: ATT00001.txt
In the News June 1, 2018
Core77 – May 31 A Clinic And Research Lab Designed To Make The Patient Experience Pleasant and Comprehensive — Emily Engle Medical spaces need a facelift, from furnishing to digital screens to the entire patient experience. This past year, Cactus team worked closely with the Mount Sinai Health System to develop Lab100, a new type of medical environment that focuses on the different ways in which developing technologies can improve how we understand and experience medical attention and healthcare. Lab100 equips scientists with longitudinal multi-scale health data and a testbed environment to develop, validate and deploy new products and services. By closing the feedback loop between discovery science and care delivery, Lab100 creates a virtuous cycle of innovation that radically accelerates the pace at which promising ideas become clinical practice. - David Stark, MD, Assistant Professor, Health System Design and Global Health, Icahn School of Medicine at Mount Sinai, Medical Director, Institute for Next Generation Health Care Learn more: http://www.core77.com/posts/77952/A-Clinic-and-Research-Lab-Designed-to-Make-the-Patient-Experience-Pleasant-and-Comprehensible
International Business Times – June 1 Mount Sinai And RenalytixAI Launch Groundbreaking Artificial Intelligence Solution For Improved Kidney Disease Management and Patient Care Mount Sinai Health System and RenalytixAI, Plc today have entered into an exclusive multi-year license and collaboration to commercialize artificial intelligence solutions to improve kidney disease detection, management and treatment for patients with diabetes and other at-risk, large-scale patient populations. “Our ability to apply the power of artificial intelligence against such a deep repository of clinical data in combination with prognostic biomarkers has the potential to change the game for all of our patients with diabetes and other populations at risk for kidney disease,” said Barbara Murphy, MD, dean for clinical integration and population health management and chair for the department of internal medicine at the Icahn School of Medicine at Mount Sinai, and chief executive officer of RenalytixAI. The accomplished innovators and rich data resources of Mount Sinai combined with the expertise and vision of our colleagues at RenalytixAI are evolving the development of cutting-edge renal prognostics for the benefit of patients and healthcare globally,” said Erik Lium, PhD, senior vice president at Mount Sinai Innovation Partners. - Barbara Murphy, MD, Dean, Clinical Integration and Population Health Management, Chair, Department of Internal Medicine, Icahn School of Medicine at Mount Sinai - Erik Lium, PhD, Senior Vice President, Mount Sinai Innovation Partners Learn more: http://markets.financialcontent.com/ibtimes/news/read/36400078 Additional coverage: Star Tribune http://markets.financialcontent.com/startribune/news/read/36400078/Mount_Sinai_and_RenalytixAI_Launch_Groundbreaking_Artificial_Intelligence_Solution_For_Improved_Kidney_Disease_Management_and_Patient_Care Pittsburgh Post-Gazette http://markets.post-gazette.com/postgazette/news/read/36400078 The Buffalo News http://markets.buffalonews.com/buffnews/news/read/36400078/Mount_Sinai_and_RenalytixAI_Launch_Groundbreaking_Artificial_Intelligence_Solution_For_Improved_Kidney_Disease_Management_and_Patient_Care Street Insider http://markets.financialcontent.com/streetinsider/news/read/36400078 Channel 8 Eyewitness News http://www.klkntv.com/story/38324263/mount-sinai-and-renalytixai-launch-groundbreaking-artificial-intelligence-solution-for-improved-kidney-disease-management-and-patient-care
Politico New York – June 1 Coked Up — Amanda Eisenberg Reprogrammed gene expression in the brain rewards circuit from cocaine use can provide clues for a new course of treatment, according to researchers at Mount Sinai. - Eric Nestler, MD, PhD, Dean, Academic and Scientific Affairs, Director, Friedman Brain Institute, Professor, Neuroscience, Pharmacological Sciences, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: https://www.politico.com/states/new-york/newsletters/politico-new-york-health-care/2018/06/01/senate-grinds-to-halt-070303 Additional coverage: Medi Magazine https://www.medimagazine.it/luso-di-cocaina-altera-lespressione-genica-nel-circuito-di-ricompensa-del-cervello/ Neuroscience News https://neurosciencenews.com/cocaine-genetics-reward-9201/ Medical Health News http://www.medicalhealthnews.net/cocaine-use-alters-gene-expression-in-brain-reward-circuits News Medical & Life Sciences https://www.news-medical.net/news/20180531/Study-highlights-complexity-of-the-braine28099s-molecular-response-to-cocaine-use.aspx Medicina TV https://www.medicinatv.com/noticias/investigadores-descubren-como-la-cocaina-afecta-a-la-expresion-genetica-en-el-cerebro
MedPage Today – May 31 Baby Teeth May Predict Autism — Judy George Zinc and copper metabolism cycles in the layers of baby teeth may be able to predict which children will develop autism spectrum disorder, a longitudinal analysis suggests. This is the first study to generate a 90 percent accurate fetal and early childhood biomarker of autism by tracking metabolic pathways over time and could lead to new diagnostic tools, reported Paul Curtin, PhD, assistant professor in the department of environmental medicine and public health at the Icahn School of Medicine at Mount Sinai, and colleagues in Science Advances. The study also represents a new direction in autism biomarker research, he added. While many studies have assessed exposure levels, this analysis examined cycles to see how metabolism might be disrupted. "With this research, we are shifting the focus to looking at metabolic cycles to understand how children are processing nutrients, as opposed to just looking at their exposure to toxicants." - Paul Curtin, PhD, Assistant Professor, Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai Learn more: https://www.medpagetoday.com/neurology/autism/73203 Additional coverage: Bioscience Technology https://www.biosciencetechnology.com/news/2018/05/clues-autism-found-baby-teeth Medicine Net https://www.medicinenet.com/script/main/art.asp?articlekey=212669
R&D Magazine – May 23 Robotically Controlled Digital Microscope Provides New Visualization System In Operating Room The Department of Neurosurgery at the Mount Sinai Health System has become one of the first hospitals in the U.S. to use Modus V, a hands-free, robotically controlled digital microscope that provides advanced visualization in the operating room. The system comprises a robotic arm featuring a high-definition camera that projects digital images of neuroanatomy on large monitors. It provides an alternative to the traditional operating microscope featuring an ocular or eyepiece that is commonly used by neurosurgeons to view magnified images of the brain. “This technology sets the stage for the next generation of digital image-based neurosurgery,” said Constantinos Hadjipanayis, MD, PhD, site chair of neurosurgery at Mount Sinai Union Square and director of neurosurgical oncology for the Mount Sinai Health System. Joshua Bederson, MD, professor and system chair of the department of neurosurgery at the Mount Sinai Health System and clinical director of the neurosurgery simulation said, “As critical information streams into multiple viewpoints in the operating room, much like in the cockpit of an aircraft, the surgeon’s goal is to utilize that information and move beyond critical structures, preserve neurologic function, and safely perform the procedure.” - Constantinos Hadjipanayis, MD, PhD, Site Chair, Neurosurgery, Mount Sinai Beth Israel, Professor, Neurosurgery, Oncological Sciences, Icahn School of Medicine at Mount Sinai - Joshua Bederson, MD, Professor, System Chair, Department of Neurosurgery, Mount Sinai Health System, Clinical Director, Neurosurgery Simulation Core Learn more: https://www.rdmag.com/news/2018/05/robotically-controlled-digital-microscope-provides-new-visualization-system-operating-room Additional coverage: News Medical & Life Sciences https://www.news-medical.net/news/20180601/Novel-microscope-technology-offers-images-of-the-brain-with-4K-resolution-and-3D-visualization.aspx Independent Recorder https://www.independentrecorder.com/brain-surgeons-obtain-a-superior-watch-from-augmented-reality-107421.html
The Daily Beast – May 31 Why Isn’t There A Lyme Disease Vaccine? — Ashley Ross Lyme disease is an infectious disease caused by the bacterium Borrelia burgdorferi. The disease is known to be difficult to diagnose, as many early symptoms are vague, like headaches and fatigue. In its earliest stages, Lyme can be combated with antibiotics—but that’s if it’s recognized early. The longer it takes to treat Lyme, the more likely it is for it to become a chronic disease. Which makes it even more odd that a vaccine for Lyme disease doesn’t exist, particularly because cases are spiking. Brian A. Kidd, PhD, assistant professor of genetics and genomic sciences at the Icahn School of Medicine at Mount Sinai said that Lyme researchers are working on genotyping different strains of bacteria to move toward more personalized diagnoses and treatment. “I think it’s important for people who are suffering with or living with the fear of Lyme disease to really have some faith and know that the tide is really changing,” said Dr. Kidd. Dr. Kidd added that researchers are using data to identify what genetics can make someone more susceptible or even resilient to Lyme and what that means for future prevention and vaccinations. - Brian A. Kidd, PhD, Assistant Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai Learn more: https://www.thedailybeast.com/why-isnt-there-a-lyme-disease-vaccine?ref=author
OncLive –May 31 Dr. Wistinghausen Discusses Targeted Therapies for Pediatric NHL Birte Wistinghausen, MD, medical director of the division of pediatric hematology-oncology at the Kravis Children’s Hospital at Mount Sinai, discusses targeted therapies for the treatment of pediatric patients with non- Hodgkin lymphoma (NHL). The Children’s Oncology Group is currently conducting trials with targeted therapies in the frontline setting. ANHL1131 is a phase II/III trial evaluating the safety and efficacy of rituximab (Rituxan) in children or adolescents with higher-risk NHL. These are patients with B-cell lymphoma or B-cell leukemia, said Dr. Wistinghausen. There is also an open study evaluating chemotherapy in combination with brentuximab vedotin (Adcetris) or crizotinib (Xalkori) in patients with newly diagnosed stage III/IV anaplastic large cell lymphoma (ALCL). - Birte Wistinghausen, MD, Medical Director, Division of Pediatric Hematology-Oncology, Kravis Children’s Hospital Learn more: https://www.onclive.com/onclive-tv/dr-wistinghausen-discusses-targeted-therapies-for-pediatric-nhl
Infectious Disease Advisor – June 1 Addressing Palliative Care In Hepatocellular Carcinoma — Jasenka Piljac Zegarac, PhD Epidemiologic research shows that hepatocellular carcinoma (HCC) is the fastest growing cause of cancer-related death in the United States. It affects predominantly people age 40 years or older and is approximately three times more common in men than in women. Patients with chronic liver disease and cirrhosis caused by chronic hepatitis B or C virus infections and those with alcoholic liver disease are at increased risk for HCC developing. Christopher D. Woodrell, assistant professor in the department of geriatrics and palliative medicine at the Icahn School of Medicine at Mount Sinai discusses the latest insights about integrating palliative care into the treatment of patients with HCC. “Patients with HCC, and older adults in particular, face unique types of challenges. Many of these patients have also been living with chronic liver disease for some time. Palliative care offers an additional layer of support to help these patients and their families navigate HCC diagnosis and treatment and maintain an acceptable quality of life,” said Dr. Woodrell. - Christopher D. Woodrell, MD, Assistant Professor, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.infectiousdiseaseadvisor.com/hepatitis-advisor/palliative-care-in-hepatocellular-carcinoma/article/769118/
Self Magazine – May 31 Primary Care Doctors Share Nine Ways To Get The Most Out Of Your Annual Checkup — Carolyn L. Todd If you can’t quite remember the last time you made it to the doctor for you annual checkup, you’re missing a huge opportunity to take your health into your own hands. Seeing your doctor at least once a year should really be non-negotiable, but there are also certain things you can do before and during your appointment to make it as worthwhile as possible. “Your primary care doctor should be your gatekeeper for understanding everything going on and piecing it together—someone who knows the whole story of you,” said Shanna Levine, MD, instructor of medicine and general internal medicine at the Icahn School of Medicine at Mount Sinai. “No patient should ever be afraid to ask their doctor anything,” said Dr. Levine. “Who else are you supposed to ask?” - Shanna Levine, MD, Instructor, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.self.com/story/annual-checkup-tips
Slate Magazine – June 1 The Best Headphones For Kids, According To Pediatric Ear Experts Finding the right protective headphones for kids is the first line of defense against the permanent hearing loss that experts have been warning about since the dawn of the iPod. Kids should only be using over-the-ear headphones with a volume limiter that reduces exposure to excessively loud noises, even if there are “kid safe” earbuds that go inside the ear. Michael Rothschild, MD, the director of pediatric otolaryngology at The Mount Sinai Hospital, said an over-the-ear set is your best bet for a comfortable fit, a noise-canceling barrier, and less irritation to the ear canal. Stellar sound quality may not seem so important, but Joey Bernstein, MD, associate professor of otolaryngology at the Icahn School of Medicine at Mount Sinai, noted that “the poorer the quality of the sound, the more likely it is for kids to crank up the volume to unsafe levels.” - Michael A. Rothschild, MD, Clinical Professor, Otolaryngology, Icahn School of Medicine at Mount Sinai, Director, Pediatric Otolaryngology, The Mount Sinai Hospital - Joseph M. Bernstein, MD, Associate Professor, Otolaryngology, Icahn School of Medicine at Mount Sinai Learn more: https://slate.com/human-interest/2018/06/best-headphones-for-kids.html
Self Magazine – May 31 How Worried Do You Really Need To Be About So-Called ‘Super-Gonorrhea?’ — Carolyn L. Todd There are an estimated 78 million new cases of gonorrhea globally every year, according to the World Health organization. In the United States, gonorrhea is the second most commonly reported sexually transmitted infection, with over 468,000 cases reported to the Centers for Disease Control and Prevention in 2016. The long-term issue is that we could run out of effective medicine for gonorrhea, said Erna Kojic, MD, senior faculty of medicine, infectious diseases at the Icahn School of Medicine at Mount Sinai and chief of the division of infectious diseases at Mount Sinai St. Luke’s and Mount Sinai West. “What we’re seeing is the emergence of an infection that we really have no good treatments for,” said Dr. Kojic. - Erna M. Kojic, MD, Senior Faculty, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai, Chief, Division of Infectious Diseases, Mount Sinai St. Luke’s, Mount Sinai West Learn more: https://www.self.com/story/super-gonorrhea-what-to-know
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 4, 2018 Date: Monday, June 04, 2018 1:38:46 PM Attachments: ATT00001.txt
In the News June 4, 2018
Healthcare IT News – June 1 Mount Sinai Teams With RenalytixAI To Employ AI and Analytics For Kidney Disease Care— Bernie Monegain Mount Sinai Health System and RenalytixAI announced that they will work together to commercialize artificial intelligence designed to improve kidney disease detection, management and treatment for patients with diabetes and other at-risk, large-scale patient populations. The partners will tap Mount Sinai’s data warehouse, which holds more than three million patient health records and 43,000 patient records in the BioMe BioBank repository. “Our ability to apply the power of artificial intelligence against such a deep repository of clinical data in combination with prognostic biomarkers has the potential to change the game for all of our patients with diabetes and other populations at risk for kidney disease,” said Barbara Murphy, MD, dean of clinical integration and population health management and chair of the department of internal medicine at the Icahn School of Medicine at Mount Sinai. Approximately one million patients cared for at Mount Sinai are either diagnosed with Type II diabetes or are of African ancestry, two of the major at-risk population segments for kidney disease. - Barbara Murphy, MD, Dean, Clinical Integration and Population Health Management, Chair, Department of Internal Medicine, Icahn School of Medicine at Mount Sinai - Erik Lium, PhD, Senior Vice President, Mount Sinai Innovation Partners Learn more: http://www.healthcareitnews.com/news/mount-sinai-teams-renalytixai-employ-ai-and-analytics-kidney- disease-care Additional coverage: Crain’s New York http://www.crainsnewyork.com/article/20180601/HEALTH_CARE/180609986/mount-sinai-partners- with-ai-startup-to-detect-and-manage-kidney-disease Crain’s Health Pulse http://www.crainsnewyork.com/article/20180604/PULSE/180609985/transgender-health-care-should- be-mainstreamed-interview (Subscription required) DOTMed https://www.dotmed.com/news/story/43202 Healthcare Analytics News http://www.hcanews.com/news/mount-sinai-announces-partnership-to-launch-renal- diseasefighting-ai-system- Health Data Management https://www.healthdatamanagement.com/news/mount-sinai-partners-with-startup-to-develop- ai-solutions-for-kidney-disease Healthcare Informatics https://www.healthcare-informatics.com/news-item/population-health/mount-sinai-apply-ai- improve-kidney-disease-detection-management Fierce Biotech https://www.fiercebiotech.com/medtech/mount-sinai-renalytixai-ally-to-use-ai-to-spot-kidney-disease The Post & Mail http://business.thepostandmail.com/thepostandmail/news/read/36404412/mount_sinai_partners_with_ai_startup_to_predict mySA https://www.mysanantonio.com/business/press-releases/article/Mount-Sinai-and-RenalytixAI-Launch- Groundbreaking-12959547.php
Newsweek – June 1 Using Cocaine Once Alters Your Brain’s Reward Circuit Forever, Study On Mice Reveals — Kashmira Gander Using cocaine, even once, has been shown to change the brain’s reward circuitry in a new study on mice. The researchers examined how six parts of the brain in control of the response to reward react when the rodents used cocaine. And while the response of mice isn't entirely comparable to humans, the researchers believe their findings could form the basis of further research into cocaine use, addiction and treatment. ”The experimental design thus allowed us to study how gene expression across brain reward regions changes over time as a result of volitional cocaine intake," said lead author Eric Nestler, MD, PhD, dean of academic and scientific affairs and director of the Friedman Brain Institute at the Icahn School of Medicine at Mount Sinai. Unlike other studies that honed in one specific gene, parts of the brain or factor of addiction, this paper tried to tie these factors together. Such studies are important. The latest figures on cocaine use in the U.S. by the State Department show that more people were using the drug in 2017 than ever before and it was easier to buy. - Eric Nestler, MD, PhD, Dean, Academic and Scientific Affairs, Director, Friedman Brain Institute, Professor, Neuroscience, Pharmacological Sciences, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.newsweek.com/using-cocaine-once-alters-your-brains-reward-circuit-forever-study-mice-953410 Additional coverage: Inverse https://www.inverse.com/article/45413-cocaine-addiction-brain-molecular-changes Reliawire https://reliawire.com/cocaine-altered-genes/ Daily Magazine http://www.dailymagazine.news/using-cocaine-once-alters-your-brain-apos-s-reward-circuit-forever- study-on-mice-reveals-nid-605690.html
Becker’s Spine Review – June 1 Mount Sinai Health System Using Zeiss Kinevo 900 For Neurosurgical Visualization — Shayna Korol Icahn School of Medicine at Mount Sinai is one of the first U.S. hospitals to use the Zeiss Kinevo 900 microscope, a robotic visualization system with 4K resolution and 3D visualization. The system works by streaming optical, navigation, and simulation information into the microscope’s eyepiece and projecting it on large monitors in the operating room so providers can view the images in real time. According to Joshua Bederson, MD, professor and system chair of the department of neurosurgery for the Mount Sinai Health System and clinical director of the neurosurgery simulation core, an advantage to projecting real-time images of the brain onto a video screen is that information sources external to the microscope can be overlaid on the monitor. - Joshua Bederson, MD, Professor, System Chair, Department of Neurosurgery, Mount Sinai Health System, Clinical Director, Neurosurgery Simulation Core Learn more: https://www.beckersspine.com/imaging/item/41328-mount-sinai-health-system-using-zeiss-kinevo-900-for- neurosurgical-visualization-5-things-to-know.html
Crain’s Health Pulse – June 4 Transgender Health Care Should Be Mainstreamed: Interview — Caroline Lewis Dr. Joshua Safer has become executive director of Mount Sinai's Center for Transgender Medicine and Surgery at a time when demand for hormones, gender-affirmation surgery and other medical services for transgender people is booming. The center saw more than 1,000 people on an outpatient basis in the past year and performed nearly 500 surgeries in the past two years, with only one full-time surgeon on staff. Volume is expected to grow when the center hires a second full- time surgeon next month. Safer spoke with Crain's Caroline Lewis about the future and challenges of transgender medicine. “We are not doing what some institutions are doing, which is finding the thing that pays the best, like surgeries. We are being thoughtful about leveraging all of the patients' needs and all the potential revenue sources and figuring out how we can do what we think is right,” Dr. Safer said about how Mount Sinai sets itself apart in serving transgender patients. - Joshua Safer, MD, Executive Director of The Center for Transgender Medicine and Surgery at Mount Sinai, Senior Faculty, Endocrinology, Icahn School of Medicine at Mount Sinai Learn more: http://www.crainsnewyork.com/article/20180604/PULSE/180609985/transgender-health-care-should-be- mainstreamed-interview
ABC Eyewitness News – June 3 Heart Surgery: Questions Every Patient Should Ask — Brandi Hitt Just hearing that you or someone you know needs to have heart surgery can be overwhelming. While you are processing the idea, you will probably be filled with questions. Experts say that asking the right questions during your consultation with a cardiac surgeon can help you approach your operation with confidence instead of fear. David H. Adams, MD, professor and system chair of cardiovascular surgery at the Icahn School of Medicine at Mount Sinai and surgeon in chief of the Mount Sinai Health System, spends about an hour with new patients, walking them through how the heart works, what the recommended procedure will accomplish and why they need it. "I like to show them their actual anatomy and compare it to normal anatomy so they really understand what their disease is," Dr. Adams said. "I think when they understand that, I think a lot of the, sort of, fear leaves them." Dr. Adams also emphasizes the importance of asking doctors about their experience, especially as it relates to the exact type of surgery you'll need. - David H. Adams, MD, Marie-Josée and Henry R. Kravis Professor, System Chair, Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai, Surgeon-in-Chief, The Mount Sinai Health System Learn more: http://abc7.com/health/heart-surgery-questions-every-patient-should-ask/3550814/ Additional coverage: WISC TV https://www.channel3000.com/news/consumer-reports-heart-surgery-questions-1/749223243
Practical Pain Management – May 30 New Imaging Tools Drive Chronic Pain Research And Understanding — Kerri Wachter Innovative technologies, developed as part of the public-private Brain Research through Advancing Innovative Neurotechnologies, or BRAIN Initiative, are allowing researchers to see the brain in ways never before possible and helping to reveal the structure and function of the circuitry involved in pain. Sarah Stanley, MBBCh, PhD, assistant professor of medicine, endocrinology, diabetes and bone disease, and neuroscience at the Icahn School of Medicine at Mount Sinai, illustrated some of this work with a brief talk on radiomagnetogenetics. Radiomagnetogenetics combine the revolutionary tools known as optogenetics and magnetogenetics to visualize causal relationships between neuronal activity and behavioral outcomes. While optogenetics allow this visualization, it can be limited by the need to “shine” light on specific cells. Magnetogenetics overcame this problem by manipulating neurons that are tagged with special proteins using magnetic stimuli. While still in animal testing, the radiomagnetogenetics’ researchers have shown that electrical or genetic modulation of neural pathways does alter pain sensation. It remains to be seen whether specific promotors can lead to cell type-specific targeting, said Dr. Stanley. - Sarah A. Stanley, MBBCh, PhD, Assistant Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: https://www.practicalpainmanagement.com/resources/news-and-research/new-imaging-tools-drive-chronic- pain-research-understanding
Cancer Network – June 4 Daratumumab/Carfilzomib Combo Effective In Lenalidomide-Refractory MM— Leah Lawrence Combining daratumumab plus carfilzomib and dexamethasone (D-Kd) in patients with lenalidomide-refractory relapsed multiple myeloma had promising efficacy and was generally well-tolerated, according to the results of a subgroup analysis of the MMY1001 trial. “Daratumumab with carfilzomib/dexamethasone is a safe and efficacious regimen regardless of prior lenalidomide exposure or refractoriness,” said Ajai Chari, MD, associate professor of medicine, hematology and medical oncology, director of clinical research in the multiple myeloma program and associate director of clinical research at the Mount Sinai Cancer Clinical Trials Office at the Icahn School of Medicine at Mount Sinai, who presented the results of the study at the 2018 Annual Meeting of the American Society of Clinical Oncology (ASCO), held June 1-5 in Chicago. “This study highlights the ability to do split dosing, particularly in community practice and to improve patient convenience,” said Dr. Chari. - Ajai Chari, MD, Associate Professor, Medicine, Hematology, Medical Oncology, Director, Clinical Research in the Multiple Myeloma Program, Associate Director, Clinical Research, Mount Sinai Cancer Clinical Trials Office, Icahn School of Medicine at Mount Sinai Learn more: http://www.cancernetwork.com/asco-multiple-myeloma/daratumumabcarfilzomib-combo-effective- lenalidomide-refractory-mm
MD Magazine – June 3 Sonali Bose, MD: Fluticasone Furoate And Other Therapies For Pediatric Asthma — Kevin Kunzmann For as good news as the US Food and Drug Administration’s (FDA) approval of fluticasone furoate (Arnuity Ellipta) was for pediatric patients with asthma, it was as welcome to physicians tasked with managing asthma in children. Sonali Bose, MD, MPH, assistant professor of medicine, pulmonary, critical care and sleep medicine at the Icahn School of Medicine at Mount Sinai, said the indication gives physicians just another option to reduce oral corticosteroid use while preserving pediatric lung function in children. “This is also great news because it also gives us the confidence to prescribe this medication in children for maintenance,” Dr. Bose said. - Sonali Bose, MD, MPH, Assistant Professor, Medicine, Pulmonary, Critical Care and Sleep Medicine, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://www.mdmag.com/post-conference-perspectives/ats-2018-perspectives/sonali-bose-md-fluticasone- furoate-and-other-therapies-for-pediatric-asthma
MedPage Today – June 1 Cardiology Culture Has Many Running For The Hills — Nicole Lou A survey of internal medicine resident physicians revealed that the top perceptions of cardiology were that, as a field, it is associated with adverse job conditions, interference with family life, and lack of diversity. Women and future non- cardiologists valued work-life balance more highly than did men or those committed to cardiology. Last fall's Transcatheter Cardiovascular Therapeutics (TCT) conference was dedicated to the theme of diversity and was supposed to be a call to attention and action for interventional cardiology. Instead, it was more of the same-old, said Roxana Mehran, MD, professor of medicine, cardiology, population health science and policy and director of interventional cardiovascular research and clinical trials at the Zena and Michael A. Weiner Cardiovascular Institute at the Icahn School of Medicine at Mount Sinai. "The intention was great; the reality, somewhat deflating. The sessions dedicated to diversity were bare. I watched many men in business suits waiting by the doors to get into the mitral and transcatheter aortic valve replacement sessions, while there were echoes in our empty rooms. Simply put, there was no interest.” - Roxana Mehran, MD, Professor, Medicine, Cardiology, Population Health Science and Policy, Director, Interventional Cardiovascular Research and Clinical Trials, Zena and Michael A. Weiner Cardiovascular Institute, Icahn School of Medicine at Mount Sinai Learn more: https://www.medpagetoday.com/publichealthpolicy/generalprofessionalissues/73220
NBC News – June 3 Melania Trump, Last Seen May 10, Won’t Attend G7 Or Singapore Summits — Tim Stelloh and Monica Alba First lady Melania Trump won’t join the president for the Group of Seven Summit in Canada this week or a planned North Korea meeting in Singapore on June 12. Mrs. Trump hasn’t made a public appearance since May 10 – found days before her embolization procedure for a “benign kidney condition.” Embolization procedures are used to block blood vessels to prevent bleeding, for example, or to block blood flow to tumors. They are often done on an outpatient basis that can require an overnight stay. Ketan Badani, MD, professor of urology at the Icahn School of Medicine at Mount Sinai, vice chairman of urology and director of the comprehensive kidney cancer program for the Mount Sinai Health System, said last month that a longer hospital stay could indicate a bleed. “That’s why they are having embolization,” he said. - Ketan Badani, MD, Professor, Urology, Icahn School of Medicine at Mount Sinai, Vice Chairman, Urology, Director, Comprehensive Kidney Cancer Program, Mount Sinai Health System Learn more: https://www.nbcnews.com/politics/white-house/melania-trump-last-seen-may-10-won-t-attend-g7-n879681 Additional coverage: AOL News https://www.aol.com/article/news/2018/06/04/melania-trump-last-seen-may-10-wont-attend-g7-or-singapore- summits/23450100/ Euro News http://www.euronews.com/2018/06/04/melania-trump-last-seen-may-10-won-t-attend-g7-n879681
Independent – June 4 Man Mystifies Researchers After Not Moving For 17-Hour Flight Between London And Perth— Joanna Whitehead A man traveling on Qantas’ recently launched 17-hour non-stop flight from Perth to London has left researchers mystified after not moving for the entire flight – even to use the bathroom. In the first collaboration of its kind between an airline and a research institution, volunteers on Qantas flights have been fitted with wearable technology to measure how flying affects mental state, anxiety levels, sleep patterns and recovery from jet-lag. Awed researchers even double-checked the equipment’s functionality, which was attached to the passenger’s wrists and thighs, to ensure that it was working correctly. The average adult is believed to urinate approximately four to seven times per day, although this is dependent on the volume and type of food and drink consumed, according to Neil Grafstein, MD, assistant professor of urology, obstetrics, gynecology and reproductive science at the Icahn School of Medicine at Mount Sinai. How much food and drink the passenger consumed is unknown. - Neil H. Grafstein, MD, Assistant Professor, Urology, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: https://www.independent.co.uk/travel/news-and-advice/qantas-flight-research-perth-london-iron-bladder- long-haul-a8382311.html
Reader’s Digest – June 1 21 Health Secrets Your Gut Is Trying To Tell You — Tina Donvito Is your digestive system a constant source of trouble and pain? Here’s what all those nagging symptoms can mean – and how to manage them. "Black-colored stool may be a sign of internal bleeding from somewhere in the digestive tract such as the stomach or small bowel," said Jack Braha, DO, chief of gastroenterology at Mount Sinai Brooklyn. Unless you've eaten dark-colored veggies like beets, taken iron supplements, or dosed yourself with Pepto Bismol, black stool may be a cause for concern. Symptoms such as weight loss, decreased appetite, fatigue, abdominal swelling, and alterations in your mental state could be the first signs of liver disease, including hepatitis, cirrhosis, or cancer. As the liver begins to enlarge, patients may experience abdominal pain on the right side near the rib cage,” said Dr. Braha. If you have these symptoms, see your doctor, especially if you have other risk factors like drug or alcohol use or obesity. - Jack Braha, DO, Chief, Gastroenterology, Mount Sinai Brooklyn Learn more: https://www.rd.com/health/conditions/gut-digestive-symptoms/
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 5, 2018 Date: Tuesday, June 05, 2018 2:36:13 PM Attachments: ATT00001.txt
In the News June 5, 2018
Bloomberg – June 4 Philanthropy Tracker: Emily and Len Blavatnik— Amanda L. Gordon Emily and Len Blavatnik, founder of Access Industries, provide $10 million to establish a women’s health research institute and expand a medical center in Chelsea that are part of the Mount Sinai Health System. The focus will be ovarian and endometrial cancers, postpartum depression, pregnancy-related deaths and severe maternal complications. The gift was made through the Blavatnik Family Foundation. - The Blavatnik Family Women’s Health Research Institute, Icahn School of Medicine at Mount Sinai Learn more: https://www.bloomberg.com/news/articles/2018-06-04/john-arnold-backs-gun-violence- research-philanthropy-tracker
Modern Healthcare – June 4 Mount Sinai Partners With AI Startup To Detect And Manage Kidney Disease— Robin Schatz Mount Sinai Health System on Friday announced an exclusive multiyear license and partnership with RenalytixAI, an artificial-intelligence startup with offices in New York and the UK. The goal is to reduce the $98 billion in preventable kidney disease and dialysis costs by predicting which patients are at the greatest risk of advanced kidney disease and taking steps to treat them early on. "The idea that we might be able to more proactively identify individuals at risk and coordinate their care in a true example of population health is very exciting," said Barbara Murphy, MD, dean of clinical integration and population health management and chair of the department of internal medicine at the Icahn School of Medicine at Mount Sinai, and chairwoman of the RenalytixAI scientific advisory board. "We're focusing on translating Mount Sinai discoveries into products that benefit patients," said Erik Lium, senior vice president at Mount Sinai Innovation Partners. "We're very pleased to be working with RenalytixAI to advance some of the technologies developed at Mount Sinai into more mature stages." - Barbara Murphy, MD, Dean, Clinical Integration and Population Health Management, Chair, Department of Internal Medicine, Icahn School of Medicine at Mount Sinai - Erik Lium, PhD, Senior Vice President, Mount Sinai Innovation Partners Learn more: http://www.modernhealthcare.com/article/20180604/NEWS/180609972 Additional coverage: Health IT Analytics https://healthitanalytics.com/news/mount-sinai-to-boost-kidney-disease- management-with-ai-big-data Becker’s Hospital Review https://www.beckershospitalreview.com/artificial-intelligence/mount-sinai-to- release-ai-kidney-care-tools-in-2019.html Fierce Biotech https://www.fiercebiotech.com/medtech/mount-sinai-renalytixai-ally-to-use-ai-to-spot- kidney-disease
The Telegraph – June 5 Dogs Can Be A Potential Risk For Future Influenza Pandemic Dogs are a potential reservoir for a future influenza pandemic, according to a study published in the journal mBio. The study demonstrated that influenza virus can jump from pigs into canines and that influenza is becoming increasingly diverse in canines. "The majority of pandemics have been associated with pigs as an intermediate host between avian viruses and human hosts. In this study, we identified influenza viruses jumping from pigs into dogs," said study investigator, Adolfo Garcia-Sastre, PhD, director of the Global Health and Emerging Pathogens Institute and professor of medicine, microbiology and infectious diseases at the Icahn School of Medicine at Mount Sinai. The researchers say it is time to think about ways to restrict the circulation of the influenza virus in dogs. The United States is free of avian influenza because every time avian influenza has been detected in poultry in this country, the chickens or turkeys are culled and eliminated from circulation," said Dr. García-Sastre. "There are attempts to restrict influenza virus in pigs through vaccination and one could consider vaccination for dogs." - Adolfo Garcia-Sastre, PhD, Director, Global Health and Emerging Pathogens Institute, Professor, Microbiology, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: https://www.telegraph.co.uk/news/0/beware-dog-flu-scientists-warn-family-pet-could- spark-next-pandemic/ Additional coverage: Dotemirates https://www.dotemirates.com/en/details/1298530539?from=dot Medical Xpress https://medicalxpress.com/news/2018-06-dogs-potential-future-influenza-pandemic.html
Medical Xpress – June 4 Digital, Mobile Advances Will Define Future Of Cardiology The future of cardiovascular care will be transformed by advances in artificial intelligence, digital health technology, and mobile as a means to prevent and treat heart disease, according to several review articles published in a Journal of the American College of Cardiology Focus Seminar on the Future Technology of Cardiovascular Care. As the type and breadth of data available to cardiologists and the cardiovascular care team continues to grow more sophisticated, physicians are increasingly being asked to provide more rapid and personalized interpretations of data to their patients. "Artificial intelligence has clear potential to enhance every stage of patient care—from research and discovery, to diagnosis, to selection of therapy," said Joel Dudley, PhD, executive vice president for precision health at the Mount Sinai Health System. "A key next step to incorporating artificial intelligence into cardiology is to align available data and technologies with clinical and business use. This way, we can prioritize short-term opportunities and understand gaps in available data or algorithms that are holding back applications of artificial intelligence in areas of high clinical need." - Joel Dudley, PhD, Director, Next Generation Healthcare Institute, Associate Professor, Genetics and Genomic Sciences, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Executive Vice President, Precision Health, Mount Sinai Health System Learn more: https://medicalxpress.com/news/2018-06-digital-mobile-advances-future-cardiology.html Additional coverage: HealthCare Business Daily News https://www.dotmed.com/news/story/43223 Science Magazine https://scienmag.com/digital-mobile-advances-will-define-future-of-cardiology/
Medical Xpress – June 5 Closing The Loop For Brain Imaging In Depression— David Mehler Depression can have a profound impact on affected individuals and those around them. It is one of the most common mental health conditions, and its symptoms include sustained feeling of sadness, hopelessness, and guilt. In severe cases, these symptoms may be aggravated by suicidal thoughts, or even attempts. Helen Mayberg, MD, senior faculty of neurosurgery, neurology, psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai and director of the center for advanced circuit therapeutics for the Mount Sinai Health System said, “Our lab takes a circuit approach to the study of major depression: Studies integrate multimodal neuroimaging strategies and quantitative behavioral and psychophysiological metrics within experimental clinical trial protocols to define brain mechanisms that mediated anti–depressant treatments.” The challenge for the ‘field’ will be to define what methods are ‘good enough’ to warrant meaningful replication studies of an encouraging finding. - Helen Mayberg, MD, Senior Faculty, Neurosurgery, Neurology, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai, Director, The Center for Advanced Circuit Therapeutics, Mount Sinai Health System Learn more: https://medicalxpress.com/news/2018-06-loop-brain-imaging-depression.html
Greenwich Free Press – June 4 Greenwich Education Group Talks Teen Migraine Triggers and Impacts — Julia Blank On Thursday night, Links Academy, a division of Greenwich Education Group hosted a talk about migraine headaches in adolescents at the YWCA of Greenwich, Migraines In Adolescents: It’s Not All In Your Head. Lauren Natbony, MD, assistant professor of neurology at the Icahn School of Medicine at Mount Sinai, gave a formal presentation and answered questions from the audience. Dr. Natbony touched upon the vast impact of migraines in multiple spheres including academic, social and emotional. She spoke of her work with various patients and developing individualized treatments. Stress, lack of sleep and disruptions in schedule can be common triggers of migraines. She emphasized the importance of families working with schools to ensure that students stay in school and don’t become isolated as a result of frequent absences. - Lauren Natbony, MD, Assistant Professor, Neurology, Icahn School of Medicine at Mount Sinai Learn more: https://greenwichfreepress.com/parenting/greenwich-education-group-talks-teen-migraine- triggers-and-impacts-107618/
WebMD – June 4 New Treatments May Boost Pancreatic Cancer Odds — Dennis Thompson Innovative ways of using chemotherapy can significantly extend the lives of patients with pancreatic cancer, one of the most deadly cancers known, two new clinical trials report. A four-drug chemo "cocktail" extended surgical patients' lives by nearly two years over the current standard single-drug chemo regimen for pancreatic cancer; a clinical trial out of France has shown. "You take overall survival from just under three years to almost five years," said Daniel Labow, MD, professor of surgery, chief of surgical oncology at the Icahn School of Medicine at Mount Sinai and site chair of the department of surgery at Mount Sinai St. Luke’s and Mount Sinai West. “That, for pancreas cancer, is a relative home run because survival in general is so poor.” Removing the pancreatic tumor using surgery is essential for long-term survival, but the patient still faces a tough road, said Dr. Labow, who wasn't involved in the studies. - Daniel M. Labow, MD, Professor, Surgery, Chief, Surgical Oncology, Hepatobiliary Surgery, Icahn School of Medicine at Mount Sinai, Site Chair, Department of Surgery, Mount Sinai St. Luke’s, Mount Sinai West Learn more: https://www.webmd.com/cancer/pancreatic-cancer/news/20180604/new-treatments-may- boost-pancreatic-cancer-odds Additional coverage: Medscape https://www.medscape.com/viewarticle/897600 U.S. News & World Report https://www.beckershospitalreview.com/artificial-intelligence/mount-sinai- to-release-ai-kidney-care-tools-in-2019.html Doctors Lounge https://www.doctorslounge.com/index.php/news/hd/80953
MD Magazine – June 4 The Importance Of Proper Inhaler Use — Kevin Kunzmann The amount of patients with asthma or chronic obstructive pulmonary disease who can properly use their inhaler is a debated number. But regardless of its true rate, the number is too low. At the 2018 American Thoracic Society International Conference this year, GlaxoSmithKline reported data which showed patients significantly struggled to manage proper inhaler use when using multiple devices versus a lone device – the triple therapy Tregely Ellipta, which is the only inhaler therapy of its kind in the US. In all the current asthma-related issues driven by pediatric obesity, pollution rates, and limited convenient therapy options, that patients being able to adhere to and proper take inhaler theapry is among the issues is almost shocking. But it’s a common conversation in the doctor’s office, said Sonali Bose, MD, MPH, assistant professor of medicine, pulmonary, critical care and sleep medicine at the Icahn School of Medicine at Mount Sinai. “Our hope is that improved adherence and improved technique in their inhaler medications will lead to downstream affects in asthma control,” added Dr. Bose. - Sonali Bose, MD, MPH, Assistant Professor, Medicine, Pulmonary, Critical Care and Sleep Medicine, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://www.mdmag.com/post-conference-perspectives/ats-2018-perspectives/the- importance-of-proper-inhaler-use
UroToday – June 4 ASCO 2018: Bladder Cancer and Germ Cell Tumors — Hanan Goldberg, MD Matthew Galsky, MD, director of the novel therapeutics program and genitourinary medical oncology at the Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai, gave a concise summary of three oral abstracts presented in a session and began with summarizing the two bladder cancer abstracts. Survival of patients with muscle invasive bladder cancer remains suboptimal, despite neoadjuvant chemotherapy and cystectomy. - Matthew Galsky, MD, Director, The Novel Therapeutics Program, Clinical Trials Program, Genitourinary Medical Oncology, The Tisch Cancer Institute at Mount Sinai, Professor, Urology, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai Learn more: https://www.urotoday.com/conference-highlights/asco-2018/asco-2018-bladder- cancer/104906-asco-2018-bladder-cancer-and-germ-cell-tumors.html
Metro NY – June 5 Ask Mount Sinai: Everything You Need To Know About Prostate Screening — Sheila Dougherty According to the Centers for Disease Control and Prevention, prostate cancer is the most common non- skin cancer among men in the United States; most men are advised to start being screened at age 50. But prostate problems don’t only happen to older men. Michael Palese, MD, chair of the department of urology for Mount Sinai Downtown, talks about men’s health and why these tests are important. “There's a lot of newer therapies and/or early detection that's available now and we're starting to see some of those benefits which really didn't exist five years ago, 10 years ago, and so that's a good thing. The main thing, I think, like any cancers, detecting it early and understanding what we're dealing with is always better than waiting until it's late stage, too late to really do anything at that point,” said Dr. Palese. - Michael A. Palese, MD, Chair, Department of Urology, Mount Sinai Downtown-Union Square Learn more: https://www.metro.us/body-and-mind/health/ask-mount-sinai-prostate-screening
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 6, 2018 Date: Wednesday, June 06, 2018 10:27:40 AM Attachments: ATT00001.txt
In the News June 6, 2018
News Channel 10 – June 6 Top Mount Sinai Executive Honored with 2018 Esperanza (Hope) Award From The Latino Commission on AIDS Jeremy Boal, MD, president of Mount Sinai Downtown and executive vice president and chief clinical officer of the Mount Sinai Health System, was presented the 2018 Esperanza Award by the Latino Commission on AIDS at their Annual Cielo Gala on Friday, June 1, at Cipriani Wall Street in Manhattan. The Esperanza Award was created by the Commission to recognize leaders in medical research, public health, and treatment dedicated to stemming the tide of HIV and AIDS. “It is an incredible honor to receive the Esperanza Award,” said Dr. Boal. “The work of the Commission is highly aligned with Mount Sinai’s commitment to provide the best health services to our community.” - Jeremy Boal, MD, President, Mount Sinai Downtown, Executive Vice President, Chief Clinical Officer, Mount Sinai Health System Learn more: http://www.newschannel10.com/story/38359287/top-mount-sinai-executive-honored-with- 2018-esperanza-hope-award-from-the-latino-commission-on-aids-at-annual-cielo-gala Additional coverage: MS News Now http://www.msnewsnow.com/story/38359287/top-mount-sinai-executive-honored-with- 2018-esperanza-hope-award-from-the-latino-commission-on-aids-at-annual-cielo-gala NBC 2 News http://www.nbc-2.com/story/38359287/top-mount-sinai-executive-honored-with-2018- esperanza-hope-award-from-the-latino-commission-on-aids-at-annual-cielo-gala KLTV News http://www.kltv.com/story/38359287/top-mount-sinai-executive-honored-with-2018- esperanza-hope-award-from-the-latino-commission-on-aids-at-annual-cielo-gala Benzinga https://www.benzinga.com/pressreleases/18/06/p11836464/top-mount-sinai-executive-honored- with-2018-esperanza-hope-award-from-
WebMD – June 5 Could Rover Unleash A Flu Pandemic? — Robert Preidt Dog lovers might be distressed by the latest research on flu pandemics. In the new study, scientists suggest that your beloved furry companion could trigger a flu pandemic among people in the future. Researchers found that flu strains can jump from pigs to dogs, and that flu is becoming increasingly diverse in dogs. "The majority of pandemics have been associated with pigs as an intermediate host between avian bird viruses and human hosts. In this study, we identified influenza viruses jumping from pigs into dogs," said study author Adolfo Garcia-Sastre, PhD, director of the Global Health and Emerging Pathogens Institute and professor of medicine, microbiology and infectious diseases at the Icahn School of Medicine at Mount Sinai. “In our study, what we found is another set of viruses that come from swine that are originally avian in origin, and now they are jumping into dogs and have been reasserted with other viruses in dogs,” he added. - Adolfo Garcia-Sastre, PhD, Director, Global Health and Emerging Pathogens Institute, Professor, Microbiology, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: https://www.webmd.com/cold-and-flu/news/20180605/could-rover-unleash-a-flu-pandemic Additional coverage: Healio: Infectious Diseases In Children https://www.healio.com/pediatrics/influenza/news/online/%7Bf4a367f9-0010-40f9-81fb- 2d98ce0b89b4%7D/pet-dogs-carry-flu-strains-that-pose-risk-to-humans Genetic Engineering & Biotechnology News https://www.genengnews.com/gen-news-highlights/dog- germs-diversify-may-threaten-humans-with-flu-pandemics/81255882 Medical News Today https://www.medicalnewstoday.com/articles/322026.php Science News https://www.sciencenews.org/article/dogs-carry-surprising-variety-flu-viruses Tech Times http://www.techtimes.com/articles/229461/20180605/scientists-warn-that-the-dog-flu-could- be-the-next-pandemic.htm Science Daily https://www.sciencedaily.com/releases/2018/06/180605103448.htm Daily Mail http://www.dailymail.co.uk/health/article-5808099/Dogs-cause-big-flu-outbreak-humans- study-warns.html Newsmax Health https://www.newsmax.com/health/health-news/dogs-source-flu- pandemic/2018/06/06/id/864480/ Deccan Chronicle https://www.deccanchronicle.com/lifestyle/health-and-wellbeing/060618/pet-dogs- could-cause-the-next-big-flu-outbreak-in-humans.html Science Codex http://www.sciencecodex.com/dogs-can-be-potential-risk-future-influenza-pandemic- 621225 Infection Control Today https://www.infectioncontroltoday.com/influenza/dogs-can-be-potential-risk- future-influenza-pandemic Drugs.com https://www.drugs.com/news/could-rover-unleash-flu-pandemic-74784.html? utm_source=ddc&utm_medium=rss&utm_campaign=Could+Rover+Unleash+a+Flu+Pandemic%3F Doctors Lounge https://www.doctorslounge.com/index.php/news/hd/80972
Daily Beast – June 6 This Top Doctor Says Transgender Hormone Therapy Is Safe— Samantha Allen How safe is transgender hormone therapy? Few have been examining that question more closely in recent years than Joshua Safer, MD, the first executive director the Center for Transgender Medicine and Surgery at Mount Sinai. So far, the answers he is finding are encouraging. Most recently, Dr. Safer helped find in an April study, that prolactin levels did not rise significantly among a sample of transgender women taking the traditional combination of estradiol and anti-androgen spironolactone, suggesting that “it may be necessary to monitor prolactin in women on this treatment combination.” The theme, Dr. Safer said, “Is that studies to date have tended to reassure that transgender hormone treatments are safer than people realized.” - Joshua Safer, MD, Executive Director of The Center for Transgender Medicine and Surgery at Mount Sinai, Senior Faculty, Endocrinology, Icahn School of Medicine at Mount Sinai Learn more: https://www.thedailybeast.com/this-top-doctor-says-transgender-hormone-therapy-is-safe
MD Magazine – June 5 Sonali Bose, MD: Respiratory Care and Research At Mount Sinai — Kevin Kunzmann As comorbidities and associations linking other conditions to asthma continue to be explored in clinical settings, facilities and practices are better off treating patients with a team-based approach across multiple disciplinaries. Such an approach has been embraced by the Mount Sinai Health System. Sonali Bose, MD, assistant professor of medicine, pulmonary, critical care and sleep medicine at the Icahn School of Medicine at Mount Sinai detailed how Mount Sinai has collaborated and initiated new means of addressing respiratory health issues. “We’re happy to announce that Mount Sinai has partnered up with National Jewish Health from Colorado to establish an independent health facility called the Mount Sinai National Jewish Respiratory Institute. And by doing that, we’ve hoped to allow for more specialty care in respiratory disease.” Dr. Bose said. “One of the efforts that’s been made has been allowing more resources to be available for patients particularly with asthma. - Sonali Bose, MD, MPH, Assistant Professor, Medicine, Pulmonary, Critical Care and Sleep Medicine, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://www.mdmag.com/post-conference-perspectives/ats-2018-perspectives/sonali-bose- md-respiratory-care-and-research-at-mount-sinai
Medscape – June 5 Gut Bacteria, Diet Significant In Multiple Sclerosis — Nancy A. Melville People with multiple sclerosis (MS) show differences in gut bacteria composition compared with those without the disease, new research shows. Addressing the issue of gut microbiota in a separate talk at the CMSC meeting, Ilana Katz Sand, MD, assistant professor of neurology at the Icahn School of Medicine at Mount Sinai and associate medical director of the Corinne Goldsmith Dickinson Center for Multiple Sclerosis, underscored the increasing interest in the bacterial composition of the gut and how it relates to MS. "We know that 70 percent of the body's immune system is housed inside the gut and there are very important communications between the immune system in the gut and the peripheral immune system, as well as direct communication between the gut and the central nervous system," she said. While results have not been published yet, Dr. Sand said the effects of diet on disease may be much more significant than many realize. "Many people are looking at the feasibility and potential for symptom management with diet changes, but I think we need to be looking at their potential as disease modifiers," she said. - Ilana Katz Sand, MD, Assistant Professor, Neurology, Icahn School of Medicine at Mount Sinai, Associate Medical Director, The Corinne Goldsmith Dickinson Center for Multiple Sclerosis Learn more: https://www.medscape.com/viewarticle/897657
MedPage Today – June 5 What Not To Try For Advance Care Planning In Dementia — Judy George An advance care planning video did not affect do-not-hospitalize directives or overall proxy preferences for advanced dementia patients, results of the EVINCE randomized clinical trial found. By six months, do-not-hospitalize directives were the same for advanced care patients whether proxies watched a 12- minute advance care video or not, according to a study published in JAMA Internal Medicine. In parts of the country where aggressive interventions occur frequently among advanced dementia patients, the intervention might be more effective but needs to be incorporated sooner, said Nathan Goldstein, MD, professor of medicine, geriatrics and palliative medicine at the Icahn School of Medicine at Mount Sinai, and Harriet Mather, MD, MSc, research program coordinator for geriatrics and palliative medicine at the Icahn School of Medicine at Mount Sinai, in an accompanying editorial. “In these regions, the focus should primarily be on improving advance care planning much earlier and not waiting until dementia is advanced,” they wrote. - Nathan E. Goldstein, MD, Professor, Medicine, Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai - Harriet L. Mather, MD, MSc, Research Program Coordinator, Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.medpagetoday.com/neurology/dementia/73303
Yahoo News – June 5 Jazz Jennings, 17, Is About To Undergo Gender Confirmation Surgery: Here’s What That Involves — Korin Miller Nearly a year after reality TV and YouTube star Jazz Jennings revealed that she plans to undergo “bottom surgery,” the transgender activist has a big announcement to share with fans: She’s going to have the surgery later this month. The surgery that Jennings is referred to is part of gender confirmation surgery, a series of surgeries that transgender patients can have to align their physical appearance with their gender identity, said Joshua Safer, MD, executive director of the Center for Transgender Medicine and Surgery at Mount Sinai. Other surgeries that transgender women may choose to undergo include facial feminization surgery and chest augmentation, he added. As Jennings has shown, it can take time for a patient to actually have the surgery once she’s decided on it. “One of the big issues now is that there is a relative shortage of surgeons who can do this in a high-quality way,” Dr. Safer said. “There’s a lot of waiting. If we could get to patients any faster, we would.” - Joshua Safer, MD, Executive Director of The Center for Transgender Medicine and Surgery at Mount Sinai, Senior Faculty, Endocrinology, Icahn School of Medicine at Mount Sinai Learn more: https://www.yahoo.com/lifestyle/jazz-jennings-undergo-gender-confirmation-surgery-heres- involves-153423051.html
MedPage Today – June 5 Clinical Challenges: Early Relapse In Follicular Lymphoma — Ian Ingram Many patients with follicular lymphoma have long-lasting remissions and can go on to live for 10 to 15 years or more following first-line treatment, but those who relapse early present a unique challenge. Often when a follicular lymphoma patient relapses, "the clock is reset" and patients can be monitored with watchful waiting or active surveillance, said Joshua Brody, MD, assistant professor of medicine, hematology and medical oncology and director of the lymphoma immunotherapy program at the Icahn School of Medicine at Mount Sinai. But in patients who relapse early, it would be the rare patient where this strategy would be viable. "Usually those patients have more aggressive disease overall," he said. -Joshua Brody, MD, Assistant Professor, Medicine, Hematology and Medical Oncology, Director, Lymphoma Immunotherapy Program, Icahn School of Medicine at Mount Sinai Learn more: https://www.medpagetoday.com/clinical-challenges/asco-lymphoma/73304
Medscape – June 5 Disrupted Sleep After Cardiac Event May Increase PTSD Risk — Megan Brooks Patients with disrupted sleep in the month after acute coronary syndrome (ACS) are at increased risk for posttraumatic stress disorder (PTSD), results of an observational study suggest. The findings were presented here at SLEEP 2018: 32nd Annual Meeting of the Associated Professional Sleep Societies. Commenting on the findings, David Rapoport, MD, professor of medicine, pulmonary, critical care and sleep medicine at the Icahn School of Medicine at Mount Sinai and director of the Sleep Medicine Research Program at Mount Sinai, noted that “people who have had a stressful event are known to develop PTSD. According to this study, people who are not sleeping after ACS are statistically likely to develop PTSD." But one shouldn't assume causality, he cautioned. "Disturbed sleep is one of the cardinal symptoms of PTSD, so I don't know if poor sleep is actually the cause of the PTSD. The conclusion that attending to sleep will prevent PTSD is probably not clearly proven by this data," said Dr. Rapoport. - David Rapoport, MD, Professor, Medicine, Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, Director of the Sleep Medicine Research Program at Mount Sinai Learn more: https://www.medscape.com/viewarticle/897635
Allure Magazine – June 6 How To Tell If Your Bloodshot Eyes Are Actually Ocular Rosacea — Kaleigh Fasanella Bloodshot eyes can be attributed to a multitude of things: allergies, a lack of sleep, or even smoking weed. But in some cases, it can be a sign of something more serious, like ocular rosacea, a condition characterized by significant inflammation of the eye and its surrounding area. Unfortunately, doctors don't know exactly what causes rosacea, and the same goes for ocular rosacea. According to Harsha Reddy, MD, assistant chief of oculoplastics and reconstructive surgery at the New York Eye and Ear Infirmary of Mount Sinai, research suggests that it's an auto-immune disease, but that genetic, bacterial, and environmental factors may also play a role in its occurrence. He adds that many people with facial rosacea also have ocular rosacea, or will develop it at a certain point. Dr. Reddy noted that it can also make you feel like you have something stuck in your eye and can cause sties in some patients. - Harsha Reddy, MD, Assistant Chief, Oculoplastics and Reconstructive Surgery, New York Eye and Ear Infirmary of Mount Sinai Learn more: https://www.allure.com/story/what-is-ocular-rosacea
Women’s Health Magazine – June 5 Everything You Need To Know About The STI — Kristin Canning With an estimated 820,000 new cases each year, gonorrhea is the second most commonly reported notifiable disease in the U.S., according to the Centers for Disease Control. Much like chlamydia, gonorrhea is hard to recognize. In fact, most women and men are asymptomatic, according to the CDC. That means they don’t experience any changes once they’re infected, said Suzanne S. Fenske, MD, assistant professor of obstetrics, gynecology and reproductive science at the Icahn School of Medicine at Mount Sinai. Only about 90 percent of cervical gonorrhea cases are found via urine tests, said Dr. Fenske, so a vaginal swab for suspected cervical gonorrhea is your best option. - Suzanne S. Fenske, MD, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: https://www.womenshealthmag.com/health/a21085491/what-is-gonorrhea/
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 7, 2018 Date: Thursday, June 07, 2018 3:22:27 PM Attachments: ATT00001.txt
In the News June 7, 2018
Politico New York – June 7 Making Rounds — Amanda Eisenberg The Latino Commission on AIDS presented Dr. Jeremy Boal, president of Mount Sinai Downtown and executive vice president and chief clinical officer of the Mount Sinai Health System, with the Esperanza Award. - Jeremy Boal, MD, President, Mount Sinai Downtown, Executive Vice President, Chief Clinical Officer, Mount Sinai Health System Learn more: https://www.politico.com/states/new-york/newsletters/politico-new-york-health-care
The Dermatologist – June 6 Breakthrough Study Could Lead To New Options for Children with Atopic Dermatitis Findings from a recent study show important phenotypic differences between children and adults with atopic dermatitis. In this article, Emma Guttman-Yassky, MD, PhD, professor of dermatology, clinical immunology, medicine, vice chair of research in the department of dermatology and director of the Center for Excellence in Eczema at the Laboratory of Inflammatory Skin Diseases at the Icahn School of Medicine at Mount Sinai, discusses these results and how they could affect the treatment of atopic dermatitis in children. - Emma Guttman-Yassky, MD, PhD, The Sol & Clara Professor, Dermatology, Clinical Immunology, Medicine, Vice Chair, Research, Department of Dermatology, Director, The Center for Excellence in Eczema, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai Learn more: https://www.the-dermatologist.com/resource/pediatric-dermatology?eclick=d
Crain’s New York – June 7 Mount Sinai’s Transgender Center Executive Director Says Transgender Health Care Should Be Mainstreamed — Caroline Lewis Dr. Joshua Safer has become executive director of Mount Sinai's Center for Transgender Medicine and Surgery at a time when demand for hormones, gender-affirmation surgery and other medical services for transgender people is booming. The center saw more than 1,000 people on an outpatient basis in the past year and performed nearly 500 surgeries in the past two years, with only one full-time surgeon on staff. Volume is expected to grow when the center hires a second full-time surgeon next month. Safer spoke with Crain's Caroline Lewis about the future and challenges of transgender medicine. “We are not doing what some institutions are doing, which is finding the thing that pays the best, like surgeries. We are being thoughtful about leveraging all of the patients' needs and all the potential revenue sources and figuring out how we can do what we think is right,” Dr. Safer said about how Mount Sinai sets itself apart in serving transgender patients. - Joshua Safer, MD, Executive Director of The Center for Transgender Medicine and Surgery at Mount Sinai, Senior Faculty, Endocrinology, Icahn School of Medicine at Mount Sinai Learn more: http://www.crainsnewyork.com/article/20180607/HEALTH_CARE/180609978/mount-sinais- executive-director-transgender-health-care-should-be
Queens Gazette – June 6 Mount Sinai Queens, UCCA Host Community Health Fair Mount Sinai Queens and the United Community Civic Association (UCCA) hosted the 19th annual Community Health Fair on Saturday, June 2, at the outdoor stage of Kaufman Astoria Studios at 36th Street and 35th Avenue. Open to the public, the free health fair is a day of health screenings and education, and fun activities for the entire family. “Mount Sinai Queens works hard to get the people in our community healthy and keep them healthy,” said Caryn A. Schwab, Executive Director of Mount Sinai Queens. “The health fair is an excellent opportunity to learn some basic personal health information and about how to use this information to improve your health and the health of your family.” Brijen Shah, MD, chief medical officer and vice president of medical affairs at Mount Sinai Queens said, “By educating the public and providing free screenings, we can help improve the health of our community. Doctors, nurses, other health care workers and staff volunteer their time to offer lectures and workshops, health screenings, and interactive programs on a wide range of health issues that we hope will empower people to make healthy lifestyle choices, which will, in turn, lead to a healthier population.” - Caryn A. Schwab, Executive Director, Mount Sinai Queens - Brijen Shah, MD, Chief Medical Officer, Vice President, Medical Affairs, Mount Sinai Queens - Ana M. Rodriguez, LCSW, Director, Community Relations and Volunteer Services, Mount Sinai Queens Learn more: http://www.qgazette.com/news/2018-06- 06/Front_Page/Mount_Sinai_Queens_UCCA_Host_Community_Health_Fair.html
Science Daily – June 6 Human Drug Addiction Behaviors Tied to Specific Impairments in Six Brain Networks The Impaired Response Inhibition and Salience Attribution (iRISA) model, first published in 2002 by Rita Goldstein, PhD, Professor of psychiatry and neuroscience and director of the Neuropsychoimaging of Addiction and Related Conditions research program at the Icahn School of Medicine at Mount Sinai, proposed that impairments of two broad neuropsychological functions - response inhibition (a cognitive process that permits individuals to inhibit their impulses) and salience attribution (the property of tagging something as valuable or important) – and their underlying neural substrates contribute to the cycle of addiction across a broad range of substances of abuse. "Our review is the first systematic approach to integrate what we know about the function of each of these networks into a comprehensive model underlying drug addiction symptomatology across the addiction cycle," said Anna Zilverstand, PhD, assistant professor of psychiatry at the Icahn School of Medicine at Mount Sinai and first author of the paper. - Rita Goldstein, PhD, Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai, Chief, Brain Imaging Core, Director, Neuropsychoimaging of Addiction and Related Conditions Research Program - Anna Zilverstand, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: https://www.sciencedaily.com/releases/2018/06/180606132718.htm
Business Insider – June 6 Digital Health Briefing: Mount Sinai Taps AI to Detect Kidney Disease — Nicky Lineaweaver New York-based Mount Sinai Health System announced a partnership with RenalytixAI, a healthcare AI startup, to create a tool that flags patients at risk of advanced kidney disease. The partners will feed Mount Sinai’s more than 3 million patient health records into a machine-learning system, developing a tool that identifies at-risk patients to inform earlier treatment interventions for improved patient outcomes. Mount Sinai’s new AI tool could inform how it treats the one million Mount Sinai patients that are either diagnosed with type II diabetes or are of African ancestry, for example — two of the major at- risk population segments for kidney disease. The partners hope to commercialize an AI product beginning in Q2 2019. - Erik Lium, PhD, Senior Vice President, Mount Sinai Innovation Partners Learn more: http://www.businessinsider.com/digital-health-briefing-apple-delivers-health-records-api- to-developers-teladoc-opens-door-to-new-global-markets-mount-sinai-taps-ai-to-detect-kidney-disease- 2018-6
Healio: Cardiology Today – June 7 Progress in Mobile Technology Can Benefit Cardiologists, Patients — Darlene Dobkowski Advances in digital health, artificial intelligence and mobile technologies may help physicians and patients prevent and treat CVD, according to three review articles published in the Journal of the American College of Cardiology. AI can help clinical practice become more convenient, efficient, effective and personalized, according to a review by Kipp W. Johnson, an MD/PhD candidate at the Institute for Next Generation Healthcare and the department of genetics and genomic sciences at the Icahn School of Medicine at Mount Sinai, and colleagues. “Artificial intelligence has clear potential to enhance every stage of patient care — from research and discovery, to diagnosis, to selection of therapy,” Joel Dudley, PhD, director of the Next Generation Healthcare Institute at the Icahn School of Medicine at Mount Sinai, said in a press release. “A key next step to incorporating artificial intelligence into cardiology is to align available data and technologies with clinical and business use. - Joel Dudley, PhD, Director, Next Generation Healthcare Institute, Associate Professor, Genetics and Genomic Sciences, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Executive Vice President, Precision Health, Mount Sinai Health System - Kipp W. Johnson, MD/PhD Candidate, Institute for Next Generation Healthcare, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai Learn more: https://www.healio.com/cardiology/arrhythmia-disorders/news/online/%7B72d4a010-46c8- 4b7c-bafe-8712c9cf1e66%7D/progress-in-mobile-technology-can-benefit-cardiologists-patients
Healio: Gastroenterology –June 6 Combined Tissue Acquisition, Imaging Identifies Most Pancreatic Cysts In this exclusive video perspective from Digestive Disease Week 2018, Christopher J. DiMaio, MD, associate professor of medicine, gastroenterology and pediatrics at the Icahn School of Medicine at Mount Sinai, discusses results of a study that examined EUS-guided microforceps biopsy for the diagnosis of pancreatic cystic lesions. “Our study was aiming to look at the use of some novel tissue acquisition and imaging techniques to see if we can better improve the diagnosis of pancreatic cysts,” Dr. DiMaio told Healio Gastroenterology and Liver Disease. - Christopher J. DiMaio, MD, Associate Professor, Medicine, Gastroenterology, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: https://www.healio.com/gastroenterology/pancreatic-disorders/news/online/%7B1ee271b5- 86a0-42f6-8065-dc9fa92c3cf8%7D/combined-tissue-acquisition-imaging-identifies-most-pancreatic-cysts
Medscape – June 7 Insomnia Common but Often Short-Lived — Megan Brooks Each year, about one quarter of Americans experience acute insomnia, but most recover without developing persistent poor sleep or chronic insomnia, a new study suggests. David Rapoport, MD, professor of medicine, pulmonary, critical care and sleep medicine at the Icahn School of Medicine at Mount Sinai and director of the Sleep Medicine Research Program at Mount Sinai, told Medscape Medical News the original work on insomnia cited an initiating factor and a perpetuating factor superimposed on a person's predisposition to insomnia. "If you are born with a tendency towards insomnia and you get stressed, you are much more likely to develop it," Dr. Rapoport explained. - David Rapoport, MD, Professor, Medicine, Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, Director of the Sleep Medicine Research Program at Mount Sinai Learn more: https://www.medscape.com/viewarticle/897772
American Veterinarian –June 7 Could Dogs Become the Source of the Next Flu Pandemic? — Amanda Carrozza As of May 2018, there have been 61 positive cases of dog flu in New York City. And with the exceptions of Hawaii, Alaska, and North Dakota, at least 1 strain of canine flu (H3N2 or H3N8) has been documented in every state—with the majority of states reporting cases of both strains. Now, researchers are speculating whether dogs could be a potential reservoir for a future influenza pandemic. This is according to a new study just published in the journal mBio that demonstrated that the influenza virus can jump from pigs into dogs and that influenza in dogs is becoming increasingly diverse. "The majority of pandemics have been associated with pigs as an intermediate host between avian viruses and human hosts. In this study, we identified influenza viruses jumping from pigs into dogs," said one of the study’s authors, Adolfo García-Sastre, PhD, director of the Global Health and Emerging Pathogens Institute and professor of medicine, microbiology and infectious diseases at the Icahn School of Medicine at Mount Sinai. - Adolfo Garcia-Sastre, PhD, Director, Global Health and Emerging Pathogens Institute, Professor, Microbiology, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: http://www.americanveterinarian.com/news/could-dogs-become-the-source-of-the-next-flu- pandemic
Everyday Health – June 6 An Immunotherapy-Chemotherapy Combo May Be A New Standard of Care for Squamous Non- Small-Cell Lung Cancer — Paul Raeburn A combination of the immunotherapy drug Keytruda (pembrolizumab) and standard chemotherapy reduced the risk of death by 36 percent in patients with metastatic squamous non-small cell lung cancer, or NSCLC, according to a report presented at the 2018 annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago. Earlier this year, data suggested that Keytruda and chemotherapy should be the standard treatment for adenocarcinoma, the most common type of lung cancer, says Thomas U. Marron, MD, PhD, assistant professor, medicine, hematology and medical oncology at the Icahn School of Medicine at Mount Sinai. “This data supports a similar combination for the treatment of squamous cell NSCLC, the second most common type of lung cancer. This is game-changing for the treatment of squamous cell NSCLC,” Dr. Marron says. - Thomas U. Marron, MD, PhD, Assistant Professor, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai Learn more: https://www.everydayhealth.com/lung-cancer/treatment/immunotherapy-chemotherapy- combo-will-new-standard-care-squamous-non-small-cell-lung-cancer/
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] From: ITNDaily Subject: Mount Sinai In The News - June 8, 2018 Date: Friday, June 08, 2018 2:11:56 PM Attachments: ATT00001.txt
In the News June 8, 2018
Health Magazine – June 7 A New Study Says ‘Dog Flu’ Could Be The Next Swine Flu. How Worried Should You Really Be? — Sarah Klein In a new study published in the journal mBio, researchers are detailing an increase in what’s called the diversity of flu viruses in dogs. Different strains of flu virus are mixing and evolving, making it more likely that one version could eventually infect a human. Plus, the researchers also found evidence that the virus can spread from pigs to pups, which makes this whole situation similar to the developments that led to widespread swine flu in 2009. "The diversity in dogs has increased so much now that the type of combinations of viruses that can be created in dogs represent potential risk for a virus to jump to a dog into a human,” said study author Adolfo Garcia-Sastre, PhD, director of the Global Health and Emerging Pathogens Institute and professor of microbiology, medicine, and infectious diseases at the Icahn School of Medicine at Mount Sinai. - Adolfo Garcia-Sastre, PhD, Director, Global Health and Emerging Pathogens Institute, Professor, Microbiology, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: http://www.health.com/cold-flu-sinus/dog-flu-pandemic
Science Daily – June 7 Active HIV In Large White Blood Cells May Drive Cognitive Impairment In Infected Mice Macrophages, large white blood cells that engulf and destroy potential pathogens, harbor active viral reserves that appear to play a key role in impaired learning and memory in mice infected with a rodent version of HIV. Chao-Jiang Gu of Icahn School of Medicine at Mount Sinai, and colleagues present these new findings in PLOS Pathogens. These findings add to growing evidence that macrophages harboring active HIV may transport HIV to the brain, leading to cognitive problems in infected people. The researchers suggest that EcoHIV infection of mice could serve as a powerful and versatile research tool for further investigation of these effects and development of strategies to prevent them. David Volsky, PhD, professor of medicine, pathology and infectious disease at the Icahn School of Medicine at Mount Sinai said, “Cognitive impairment is a common problem in a wide variety of human conditions including diabetes, aging, and Alzheimer's Disease. Studies in the EcoHIV model of cognitive impairment may have broad implications for better understanding and treatment of these conditions as well." - David J. Volsky, PhD, Professor, Medicine, Pathology, Infectious Diseases, Icahn School of Medicine at Mount Sinai - Chao-Jian Gu, PhD, Department of Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: https://www.sciencedaily.com/releases/2018/06/180607141038.htm
Politico New York – June 8 Heart Health — Amanda Eisenberg Mount Sinai Heart will host its 21st annual Live Symposium of Complex Coronary, Valvular and Vascular Cases from June 12 to June 15. - Mount Sinai Heart Learn more: https://www.politico.com/states/new-york/newsletters/politico-new-york-health- care/2018/06/08/individual-mandate-pressure-mounts-072706
Politico New York – June 8 Drug Addiction — Amanda Eisenberg Cognitive and emotional impairments in the brain support the cycle of drug addiction, according to a review of more than 10 studies by experts at the Icahn School of Medicine at Mount Sinai. - Rita Goldstein, PhD, Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai, Chief, Brain Imaging Core, Director, Neuropsychoimaging of Addiction and Related Conditions Research Program - Anna Zilverstand, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: https://www.politico.com/states/new-york/newsletters/politico-new-york-health- care/2018/06/08/individual-mandate-pressure-mounts-072706 Additional coverage: Live Science https://www.livescience.com/62767-drug-addiction-alters-six-brain-networks.html
OncLive – May 31 OncLive Salutes 21 Visionaries With Giants Of Cancer Award Twenty-one changemakers have been selected to receive a 2018 OncLive Giants of Cancer Care®award. Recipients must be catalysts for change, demonstrating great accomplishment, imagination, inspiration, courage, and—perhaps most important—a true sense of urgency. The 2018 winners were recognized on Thursday, May 31, during an exclusive celebration at the Adler Planetarium in Chicago, Illinois. One of the recipients is Bart Bargolie, MD, professor of medicine in the department of hematology and oncology at the Icahn School of Medicine at Mount Sinai. Dr. Bargolie has been at the forefront of many research efforts in the advancement of knowledge about multiple myeloma. - Bart Bargolie, MD, Professor, Medicine, Department of Hematology and Oncology, Icahn School of Medicine at Mount Sinai Learn more: https://www.onclive.com/publications/oncology-live/2018/vol-19-no-11/onclive-salutes-21- visionaries
Crain’s Health Pulse – June 8 St. Luke’s Plans $3M Psych Ward Upgrade — Caroline Lewis Mount Sinai St. Luke's is seeking state approval for a nearly $3 million renovation of its adult inpatient psychiatric unit. The project involves a makeover of 10,729 square feet of the 29-bed unit on the ninth floor of the hospital's Clark Building, according to a certificate-of-need application submitted to the state. The unit, which primarily serves geriatric patients, would be updated to make the bathrooms compliant with the Americans with Disabilities Act. The renovation would include the addition of new quiet rooms, a new nurses station and new security windows, among other improvements. - Mount Sinai St. Luke’s Learn more: http://www.crainsnewyork.com/article/20180608/PULSE/180609929/nyu-langone-health- tests-out-amazon-business-programs (Subscription Required)
Becker’s Hospital Review – June 7 Mount Sinai Takes Notes From Hospitality Industry To Adapt To New Patient Expectations Matthew Grob, senior director of IT governance and consulting at the Mount Sinai Health System will speak on a panel during the Becker’s Hospital Review 4th Annual Health IT + Revenue Cycle Conference that is titled “HIT Security & Privacy: Best Practices and Key Issues,” at 9 am Thursday, September 20. “In order to be successful, health IT professionals need to know not just the technology, but how it's used in a healthcare environment. We need to make sure that the solutions we offer and support enable clinicians to do their jobs more effectively and more safely,” he said. - Matthew Grob, Senior Director, IT Governance and Consulting, Mount Sinai Health System Learn more: https://www.beckershospitalreview.com/hospital-management-administration/mount-sinai- takes-notes-from-hospitality-industry-to-adapt-to-new-patient-expectations-3-questions-with-it-leader- matthew-grob.html
Cure Today – June 7 Beliefs On Palliative, Hospice Care Influence Use In Advanced Lung Cancer Among Minorities — Kristie L. Kahl Minority patients with advanced lung cancer reported they are more likely to prefer palliative care rather than hospice and had less favorable beliefs about hospice care compared with non-minority patients, according to study results presented at the 2018 ASCO Annual Meeting. Lung cancer is a disease that is often associated with a high morbidity and mortality rate, which is also increasingly reflective among racial and ethnic minorities. “One of the things we know is that palliative and hospice care can be extremely helpful for patients with advanced cancer, and yet, racial and ethnic minorities often have higher morbidity and less report of medical care that is in line with their wishes,” said Cardinale Smith, MD, associate professor of medicine, hematology and medical oncology, geriatrics and palliative medicine at the Icahn School of Medicine at Mount Sinai. This can be addressed with the integration of palliative and hospice care, which, with early integration in to standard oncologic care for patients with advanced lung cancer, has proven to improve quality of life, mood and survival. - Cardinale Smith, MD, Associate Professor, Medicine, Hematology and Medical Oncology, Geriatrics, Palliative Medicine, Icahn School of Medicine at Mount Sinai, Director, Quality for Cancer Services, Mount Sinai Health System Learn more: https://www.curetoday.com/articles/beliefs-on-palliative-hospice-care-influence-use-in- advanced-lung-cancer-among-minorities
Patient Power – June 5 ASCO 2018: The Pace of Research Quickens For Personalizing Care For Lung Cancer Patients Nicholas Rohs, MD, assistant professor of medicine, hematology, and medical oncology at the Icahn School of Medicine at Mount Sinai and attending physician of hematology and medical oncology at the Mount Sinai Downtown - Chelsea Center, talks about the latest developments in lung cancer care and treatment research. Dr. Rohs discusses the data presented for both branches of lung cancer; small cell and non-small cell lung cancer, and the momentum toward more personalized medicine. Dr. Rohs also explains how understanding genetic mutational status has influenced treatment strategy, promising immunotherapy and combination therapy approaches in current studies, and potential crossover therapies that may treat more than one cancer. - Nicholas Rohs, MD, Assistant Professor, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, Attending Physician, Hematology and Medical Oncology, Mount Sinai Downtown – Chelsea Center Learn more: https://www.patientpower.info/video/asco-the-pace-of-research-quickens-for-personalizing- care-for-lung-cancer-patients?autoplay=1
Medscape – June 3 Chemo Not Needed For Most Early Breast Cancer: TAILORx — Roxanne Nelson, BSN, RN Adjuvant chemotherapy is not necessary for a large proportion of women with early-stage breast cancer, according to new findings that experts agree are "practice changing." The results come from a federally funded study, the Trial Assigning IndividuaLized Options for TReatment (TAILORx), which involved more than 10,000 patients and tested the 21-tumor gene expression assay. Charles L. Shapiro, MD, director of cancer survivorship and translational breast cancer research at the Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai, emphasized that “this is definitely practice changing.” He added, “We knew about the low-risk patients and could pretty much select those out as they didn't need chemotherapy, and we knew that the high-risk patients did need chemotherapy." However, the situation was quite different with intermediate-risk patients, and there was always a question as to whether they needed chemotherapy. "Many of us were uncertain about what to do," said Dr. Shapiro. - Charles Shapiro, MD, Director, Cancer Survivorship, Translational Breast Cancer Research, The Tisch Cancer Institute, Professor, Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.medscape.com/viewarticle/897537#vp_2
Medscape – May 17 Director Resigns As Irish Cervical Screening Scandal Escalates — Roxanne Nelson, BSN, RN Amid public outrage and a growing scandal over cervical cancer screening, in which women were told they were fine and later found to have had cancer after all, the director general of Ireland's Health Service Executive (HSE) has resigned. Stephanie Blank, MD, a professor of gynecologic oncology at the Icahn School of Medicine at Mount Sinai and director of women’s health at Mount Sinai Chelsea Center, noted that “cervical cancer is a preventable disease and the best way to prevent it is to have boys and girls receive the HPV vaccine prior to sexual debut." She added that “co-testing or HPV testing alone would likely have resulted in fewer false-negatives.” - Stephanie V. Blank, MD, Professor in the Division of Gynecologic Oncology, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, and Director of Women's Health, Mount Sinai Downtown- Chelsea Center Learn more: https://www.medscape.com/viewarticle/896764#vp_3
Medscape – June 7 ERCP During Lab Chole Tied To Best Outcomes For Choledocholithiasis — Marilynn Larkin For patients with gallstones in the common bile duct, a so-called rendezvous approach is associated with the highest rates of safety and success compared with three other techniques, researchers in Italy say. The rendezvous approach, as described by the authors, involves laparoscopic cholecystectomy (LC) plus intraoperative endoscopic retrograde cholangiopancreatography (ERCP). The Italian team conducted a systematic review and network analysis to compare outcomes with this approach to outcomes with LC plus preoperative or postoperative ERCP, or with common bile duct exploration during LC (LCDBE). Matthew Dong, MD, assistant professor of metabolic endocrine and minimally invasive surgery at the Icahn School of Medicine at Mount Sinai said, “the authors did an admirable job of trying to account for study variance and draw the best conclusions they could from the available information." He added, “This is intuitive because if this procedure is done before or after the surgery, it will frequently be performed on a different day, often in a different facility. Complications vary depending on the management strategy employed." - Matthew L. Dong, MD, Assistant Professor, Metabolic Endocrine and Minimally Invasive Surgery, Icahn School of Medicine at Mount Sinai Learn more: https://www.medscape.com/viewarticle/897743
U.S. News & World Report – June 7 How To Treat Sunburn Fast— Anna Medaris Miller Remember when tanning beds, tanning oils and even aluminum reflectors to accelerate the sun’s ability to tan your skin were cool? More people are becoming educated that these burns – though they may seem insignificant at the time – the later on damage is important to think about. That damage includes accelerated skin aging and most seriously, a greater potential for skin cancer, which studies show is more likely with a history of sunburn, said Cameron K. Rokhsar, MD, associate clinical professor of dermatology at the Icahn School of Medicine at Mount Sinai. "We know that the two most common skin cancers are directly related to amount of sun exposure received over a lifetime," he said. - Cameron K. Rokhsar, MD, Associate Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: https://health.usnews.com/wellness/articles/how-to-treat-sunburn-fast
Shape Magazine – June 7 Everything You Need To Know About Getting Rid Of Blackheads — Melanie Rud Chadwick Blackheads can mar an otherwise flawless complexion, are annoyingly hard to get rid of, and can affect anyone and everyone. Contrary to what you may think, it's not dirt that gives a blackhead its color. Blackheads occur when pores become clogged with oil and dead cells from inside the pore; the black color comes from oxidation of the oil and cells when they're exposed to oxygen, explains Neal Schultz, MD, assistant clinical professor of dermatology at the Icahn School of Medicine at Mount Sinai. A thin layer of skin covers the pus underneath, so it can’t oxidize. And with a blackhead, unlike a pimple or whitehead, there’s no inflammation, which is why there’s no redness involved. - Neal B. Schultz, MD, Assistant Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: https://www.shape.com/lifestyle/beauty-style/how-to-get-rid-of-blackheads
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 11, 2018 Date: Monday, June 11, 2018 2:01:56 PM Attachments: ATT00001.txt
In the News June 11, 2018
The Wall Street Journal – June 9 Hospitals Address Widespread Doctor Burnout — Lucette Lagnado Doctors who feel stressed or burned out are getting some urgent care. To address what experts view as a national epidemic of physician discontent, hospitals are expanding their c-suites with the new position of chief wellness officer. In recent years hospitals have tried a variety of wellness programs, but there is a sense this approach didn’t treat the causes of physician angst and alienation. Jonathan Ripp, MD, senior associate dean of well-being and resilience at the Icahn School of Medicine at Mount Sinai and chief wellness officer for the Mount Sinai Health System, said that stress and burnout affect senior physicians as well as resident and medical students. One priority is reducing clerical duties. A leading cause of physician distress is electronic record-keeping, which requires doctors to do clerical and billing work, and cuts into time with patients. It has also increased “Pajama Time,” the hours doctors devote at home to electronic charting that wasn’t finished during the day, Dr. Ripp says. One solution is having doctors dictate notes directly into electronic records. He envisions a team approach where doctors focus on clinical care and leave some tasks to others. By shaving administrative minutes here and there, Dr. Ripp aims to reduce nightly electronic work by an hour. - Jonathan A. Ripp, MD, Senior Associate Dean, Well-Being and Resilience, Chief Wellness Officer, Associate Dean, Trainee Well-Being in Graduate Medical Education, Associate Professor, Medicine, General Internal Medicine, Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai - Antonia S. New, MD, Professor, Psychiatry, Residency Training Director, Vice Chair, Education, Department of Psychiatry, Icahn School of Medicine at Mount Sinai - Lauren Peccoralo, MD, MPH, Assistant Professor, Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.wsj.com/articles/hospitals-address-widespread-doctor-burnout-1528542121 (Subscription required).
The New York Times – June 11 Can Low-Intensity Care Solve High Health Costs? — Dhruv Khullar and Austin Frakt How much you spend on medical care depends on what you get, but also where you get it. A study of Medicare hospitalizations found that almost all patients are more likely to survive at teaching hospitals, which tend to be more expensive. Amid our enthusiasm for more efficient care settings, we should be clear-eyed about the limitations: Sometimes less is more, but sometimes more is more. Other academic centers are sending patients not to another hospital, but directly home. In 2014, the Mount Sinai Health System began a hospital-at-home program for patients sick enough to need a hospital but stable enough to be cared for at home. Patients get visits from doctors, nurses, physical therapists and social workers, and they can have intravenous antibiotics, lab draws and breathing treatments in the comfort of their home. Research suggests that care for patients treated at home costs less and results in fewer complications, higher satisfaction and lower mortality. - Mount Sinai Health System Learn more: https://www.nytimes.com/2018/06/11/upshot/can-low-intensity-care-solve-high-health-care- costs.html?hpw&rref=upshot&action=click&pgtype=Homepage&module=well-region®ion=bottom- well&WT.nav=bottom-well
Forbes – June 8 See How This Hospital Uses Artificial Intelligence To Find Kidney Disease — Jennifer Kite-Powell The role of artificial intelligence (AI) in healthcare continues to rise. Mount Sinai Hospital announced a partnership with the AI healthcare startup, RenalytixAI, to create an AI tool that identifies patients at the hospital who are at risk for advanced kidney disease. Mount Sinai and RenalytixAI will put more than 3 million patient health records into the AI tool to identify at-risk patients. “This venture is bringing the promise of personalized medicine and population health to fruition," said Barbara Murphy, MD, dean of clinical integration and population health and chair of the department of medicine at the Icahn School of Medicine at Mount Sinai, and chair of the RenalytixAI Scientific Advisory board. - Barbara Murphy, MD, Dean, Clinical Integration and Population Health, Chair, Department of Medicine, Icahn School of Medicine at Mount Sinai - Erik Lium, PhD, Senior Vice President, Mount Sinai Innovation Partners Learn more: https://www.forbes.com/sites/jenniferhicks/2018/06/08/see-how-this-hospital-uses-artificial- intelligence-to-find-kidney-disease/#6df907572e8f
Smithsonian Magazine – June 8 The Next Flu Pandemic Might Come From Dogs — Brigit Katz A new study has found that influenza viruses from pigs – which have previously transmitted dangerous strains of the flu to humans – can jump into dogs. What’s more, canine flu viruses are becoming increasingly diverse. “In our study, what we found is another set of viruses that come from swine that are originally avian in origin, and now they are jumping into dogs and have been re-assorted with other viruses in dogs,” said co-author, Adolfo Garcia-Sastre, PhD, director of the Global Health and Emerging Pathogens Institute and professor of microbiology, medicine and infectious diseases at the Icahn School of Medicine at Mount Sinai. “They are starting to interact with each other. This is very reminiscent of what happened in swine ten years before the H1N1 pandemic.” - Adolfo Garcia-Sastre, PhD, Director, Global Health and Emerging Pathogens Institute, Professor, Microbiology, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: https://www.smithsonianmag.com/smart-news/say-it-aint-so-next-flu-pandemic-might- come-dogs-180969289/
You’re The Expert Podcast – June 8 Chemicals In Our Teeth Christine E. Austin, PhD, postdoctoral fellow of environmental medicine and public health at the Icahn School of Medicine at Mount Sinai studies childhood exposure to chemical, stress and development. She gets all her information from a tiny tooth. - Christine E. Austin, PhD, Postdoctoral Fellow, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai Learn more: https://theexpertshow.com/listen
DiaTribe News – June 8 ADA 2018: Trends In Insulin Pen Priming —Kelly L. Close At the American Diabetes Association 78th Scientific Sessions this year, first author, Grenye O’Malley, MD, chief endocrine fellow in the division of endocrinology and bone disease at the Icahn School of Medicine at Mount Sinai, and final author Carol Levy, MD, CDE, director of the Mount Sinai Diabetes Center at the Icahn School of Medicine at Mount Sinai will be presenting a late-breaker modestly titled “Trends in Insulin Pen Priming,” which seems likely to include data from the three-month NIH-funded study of TypeZero’s inControl MDI Advisor, which is using NFC-enabled NovoPen Echos and connected Tresiba pens supplied by Novo Nordisk. - Carol Levy, MD, CDE, Associate Professor, Endocrinology, Diabetes and Bone Disease, Obstetrics, Gynecology and Reproductive Science, Director, Mount Sinai Diabetes Center, T1 Diabetes Clinical Research, Icahn School of Medicine at Mount Sinai - Grenye O’Malley, MD, Chief Endocrine Fellow, Division of Endocrinology and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: No web link available.
Univision: Nueva York – June 8 Suicides By Bourdain And Spade Reveal A Growing Public Health Problem According to a recent report from the Centers for Disease Control and Prevention, the suicide rate has been increasing in almost every state in the country in recent years and is already the tenth leading cause of death in the United States. Hansel Arroyo, MD, psychiatry director of Mount Sinai’s Center for Transgender Medicine and Surgery and associate professor of psychiatry at the Icahn School of Medicine at Mount Sinai weighs in on the recent events and statistics. - Hansel Arroyo, MD, Psychiatry Director, Mount Sinai’s Center for Transgender Medicine and Surgery, Associate Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: https://www.univision.com/nueva-york/wxtv/noticias/suicidios/suicidios-de-bourdain-y- spade-dejan-al-descubierto-un-problema-de-salud-publica-que-van-en-aumento-video
Healio: Endocrine Today – July 11 Clinical Exposure Key To Closing Education Gap In Transgender Care — Jennifer Byrne Substantial strides have been made in physician education and cultural competency in caring for transgender patients, but gaps remain in the areas of familiarity and comfort with this population, according to Joshua Safer, MD, executive director of the Mount Sinai Center for Transgender Medicine and Surgery and senior faculty member of endocrinology at the Icahn School of Medicine at Mount Sinai. “It’s been known for a number of years now that when asked to describe the barriers to transgender care, the No. 1 problem isn’t insurance, or any of those other issues you might expect,” said Dr. Safer. “It’s a lack of physicians who know what they’re doing.” When students learn about endocrinology and hormones, the curriculum addresses hormone therapy for transgender patients. For each section in the curriculum, Dr. Safer said, he began to see improvement in the students’ comfort level. - Joshua Safer, MD, Executive Director of The Center for Transgender Medicine and Surgery at Mount Sinai, Senior Faculty, Endocrinology, Icahn School of Medicine at Mount Sinai Learn more: https://www.healio.com/endocrinology/reproduction-androgen- disorders/news/online/%7Bb7f13e82-fd12-4fbe-a114-65575dbc4042%7D/clinical-exposure-key-to-closing- education-gap-in-transgender-care
Healio – June 8 Educational Video Does Not Affect Dementia Care — Alaina Tedesco An advance care planning video did not impact preferences, do-not-hospitalize directives or burdensome treatments for patients with advanced dementia, according to findings published in JAMA Internal Medicine. In an accompanying editorial, Nathan Goldstein, MD, professor of medicine, geriatrics and palliative medicine at the Icahn School of Medicine at Mount Sinai, and Harriet Mather, MD, MSc, research program coordinator for geriatrics and palliative medicine at the Icahn School of Medicine at Mount Sinai, point out that dementia affects millions of patients and is expected to affect even more as the baby-boomer generation continues to age. “Mitchell and colleagues’ outstanding work in this study demonstrates just how complicated advance care planning is in this population and how we must continue to work to improve the care of these individuals to ensure that the treatments they receive optimize quality of life and are ultimately aligned with their values, goals and preferences,” they wrote. - Nathan E. Goldstein, MD, Professor, Medicine, Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai - Harriet L. Mather, MD, MSc, Research Program Coordinator, Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.healio.com/internal-medicine/psychiatry/news/online/%7B05c1e940-53ec-4f63- 9841-f177934e221f%7D/educational-video-does-not-affect-dementia-care
Metropolis Magazine – June 8 How Architects Can Help Make The Built Environment Healthier — Sam White Faced with a challenge as important as environmental justice, architects must seek out and engage in a dialogue with potential collaborators from other disciplines. But what form might this exchange take? On March 1 Metropolis’s director of design innovation, Susan S. Szenasy, led a talk at CookFox’s New York office that teased out answers to this question. The conversation gathered experts in the seemingly disparate fields of public health, commercial real estate, and sustainable architecture, and it quickly became clear just how deeply the goals of these disciplines are interwoven. After all, “chronic health conditions are rooted in built spaces,” said Maida Galvez, MD, MPH, associate professor of pediatrics, environmental medicine and public health at the Icahn School of Medicine at Mount Sinai. Dr. Galvez delivered an empowering message that set the tone for the rest of the discussion. “The tools are in your hands,” she said, suggesting that practical design solutions can be found to address problems such as low-level lead exposure and toxic stress. - Maida Galvez, MD, MPH, Associate Professor, Environmental Medicine and Public Health, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://www.metropolismag.com/architecture/cookfox-architecture-health/
Greenwich Patch – June 7 Migraines In Adolescents: ‘It’s Not All In Your Head’ — Sue Moretti Rogers Lauren Natbony, MD, assistant professor of neurology at the Icahn School of Medicine at Mount Sinai gave a presentation at the YWCA Greenwich entitled Migraines In Adolescents: Its’ Not All In Your Head. The presentation focused on what parents and educators need to know about migraines in young adults. Dr. Natbony affirmed that migraines “impact all domains of life” and that a migraine in not “just a headache.” During her talk, Dr. Natbony suggested that medication is not necessarily the only solution. In fact, she shared details of studies in which the utilization of an exercise plan in the treatment of migraines generated favorable outcomes that were comparable to the results achieved by the use medication alone. - Lauren Natbony, MD, Assistant Professor, Neurology, Icahn School of Medicine at Mount Sinai Learn more: https://patch.com/connecticut/greenwich/migraines-adolescents-it-s-not-all-your-head
Multiple Myeloma Hub – June 7 ASCO 2018: Subgroup Analysis Of The MMY1001 Trial —Stephanie Hill Ajai Chari, MD, associate professor of medicine, hematology and medical oncology and director of clinical research in the multiple myeloma program at the Icahn School of Medicine at Mount Sinai, discusses the Subgroup analysis of the MMY1001 trial to assess daratumumab, carfilzomib, and dexamethasone. “An important development from this study is the ability to give daratumumab as a split dose because one of the limitations of using daratumumab in the community setting is the long first infusion with a median of seven hours. Here, we showed that you could do split dosing of dara over two days and the median infusion time was approximately four hours,” he said. - Ajai Chari, MD, Associate Professor, Medicine, Hematology, Medical Oncology, Director, Clinical Research in the Multiple Myeloma Program, Associate Director, Clinical Research, Mount Sinai Cancer Clinical Trials Office, Icahn School of Medicine at Mount Sinai Learn more: http://www.multiplemyelomahub.com/medical-information/ajai-chari-asco-2018-subgroup- analysis-of-the-mmy1001-trial Additional coverage: eCancer News https://ecancer.org/video/6951
International Myeloma Foundation – June 4 Daratumumab In Combination With Carfilzomib And Dex In Len-Refractory Patients With RMM Ajai Chari, MD, associate professor of medicine, hematology and medical oncology and director of clinical research in the multiple myeloma program at the Icahn School of Medicine at Mount Sinai discusses using daratumumab in combination with carfilzomib and dexamethasone in lenalidomide- refractory patients with relapsed multiple myeloma. “The purpose of this study was to look at the safety of the addition of daratumumab to various backbone drugs in myeloma,” he said. - Ajai Chari, MD, Associate Professor, Medicine, Hematology, Medical Oncology, Director, Clinical Research in the Multiple Myeloma Program, Associate Director, Clinical Research, Mount Sinai Cancer Clinical Trials Office, Icahn School of Medicine at Mount Sinai Learn more: https://www.youtube.com/watch?v=FY009m8sW0Y Additional coverage: eCancer News https://ecancer.org/video/6950
Healio: Gastroenterology – June 11 More UC Patients Achieve Remission With Entyvio vs. Anti-TNF — Alex Young Patients with ulcerative colitis treated with Entyvio had higher remission rates compared with patients treated with TNF antagonists, according to research presented at Digestive Disease Week. David Faleck, MD, post graduate in the department of gastroenterology at the Icahn School of Medicine at Mount Sinai, reported that Entyvio effectively treated patients with moderate-to-severe active ulcerative colitis who failed or were intolerant to conventional therapy or TNF-antagonists. “We’ve seen in clinical practice that prior exposure to anti-TNF therapy is a predictor of reduced vedolizumab effectiveness,” he said during his presentation. “As is the case with much of IBD literature, we have no randomized head-to-head trials of these two agents or classes, which complicates comparison.” - David M. Faleck, MD, Post Graduate, Medicine, Department of Gastroenterology, Icahn School of Medicine at Mount Sinai Learn more: https://www.healio.com/gastroenterology/inflammatory-bowel- disease/news/online/%7Be6b57b44-94c6-4f51-ab16-93bf94aa7e9b%7D/more-uc-patients-achieve- remission-with-entyvio-vs-anti-tnf
AJMC News – June 8 Is There A Link Between Autism, Food Allergies? Study Offers Hint But No Answers — Allison Inserro Researchers say they’ve found an association between autism spectrum disorder and allergic conditions in children—especially food allergies—in the largest study looking at the issue to date, but noted more research is needed before fully understanding any possible link between the two conditions. A leading pediatric allergist also cautioned against drawing any conclusions from the study. Scott Sicherer, MD, professor of pediatrics, allergy and immunology and chief of the division of allergy and immunology of the Elliot and Roslyn Jaffe Food Allergy Institute at the Icahn School of Medicine at Mount Sinai, said more studies are required in order to understand any possible biological pathways between the two conditions, both of which have been rising. - Scott Sicherer, MD, Professor, Pediatrics, Allergy and Immunology, Chief, Division of Allergy and Immunology, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai Learn more: http://www.ajmc.com/newsroom/is-there-a-link-between-autism-food-allergies-study-offers- hint-but-no-answers tctMD – June 8 Platelet Reactivity Linked With Ischemic Stroke Risk Post DES-Implantation: ADAPT-DES Substudy — Yael L. Maxwell High platelet reactivity in patients taking clopidogrel who have already had a successful coronary DES implantation is associated with a greater risk of ischemic stroke, according to post hoc analysis of the ADAPT-DES study. However, experts are warning against the temptation to use more potent P2Y12 inhibition in the hopes of preventing noncoronary events. “I believe that this is something that clinicians should have in the back of their minds in the sense that you are not only preventing events within the stent. You are probably having benefits also outside the stent, outside the coronary vasculature in terms of prevention of spontaneous MI, probably prevention of cerebrovascular events, and possibly you have to consider peripheral artery events,” said lead study author Gennaro Giustino, MD, post graduate of general internal medicine at the Icahn School of Medicine at Mount Sinai. “It sometimes gets forgotten, but it is something that is important to discuss with our patients when we are making decisions about antiplatelet therapy.” - Gennaro Giustino, MD, Post Graduate, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.tctmd.com/news/platelet-reactivity-linked-ischemic-stroke-risk-post-des- implantation-adapt-des-substudy
HealthiNation – June 4 The 8 Things You Should Do Every Day If You’re Genetically At Risk Of A Heart Attack — Tina Donvito Scientists are just learning about the role specific genes have on your risk of getting a heart attack. Although research is ongoing, what doctors know for sure is that having an immediate family member who had cardiovascular problems before 60 years old is concerning for your own health, said Mary Ann McLaughlin, MD, medical director of the Cardiac Health Program and co-director of the Women’s Cardiac Assessment and Risk Evaluation Program at the Mount Sinai Hospital. If early heart problems have occurred in your family, she recommends you have your cholesterol, blood pressure, and blood sugar tested. Your doctor may recommend certain medications to help control blood pressure or cholesterol based on the results. - Mary Ann McLaughlin, MD, Associate Professor, Medicine, Cardiology, Assistant Professor, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Medical Director, Cardiac Health Program, Co-Director, Women’s Cardiac Assessment and Risk Evaluation Program, The Mount Sinai Hospital Learn more: https://www.healthination.com/health/genetic-risk-heart-attack-lifestyle-changes
Huffington Post – June 8 How A Diuretic Called Spironolactone Can Be Used To Treat Acne — Kristen Adaway With all of the acne treatments on the market, deciding on which one to use can be a pain. Recent research found that spironolactone may be just as effective in the treatment of hormonal acne, with similar rates of patients sticking with each treatment over a year. As with every supposed “miracle product,” there are limitations with spironolactone ― the main one being that it’s only effective in treating women’s acne. Angela Lamb, MD, assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai and director of the Westside Mount Sinai Dermatology Faculty Practice, said that she would not prescribe spironolactone to men due to its hormone-blocking properties. This includes androgen, which, if found in high levels in women, may contribute to the development of cystic acne, Dr. Lamb said. - Angela Lamb, MD, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Westside Mount Sinai Dermatology Faculty Practice Learn more: https://www.huffingtonpost.com/entry/diuretic-next-acne- solution_us_5b16a804e4b0fc3b3196ef33
Fitbit Blog – June 1 Ant-Acne Diet? Here’s What Dermatologists Actually Recommend — Jenna Birch Although some small studies show an association between increased acne and foods with a high- glycemic index (white bread, sugar, processed cereals), there are no “rigorous” studies proving certain foods cause breakouts, said Hooman Khorasani, MD, assistant clinical professor of dermatology and chief of the division dermatologic and and cosmetic surgery at the Icahn School of Medicine at Mount Sinai. He discusses five nutrient-dense foods that can support healthy skin when part of a balanced diet. - Hooman Khorasani, MD, Assistant Clinical Professor, Dermatology, Chief, Division of Dermatologic and Cosmetic Surgery, Icahn School of Medicine at Mount Sinai Learn more: https://blog.fitbit.com/foods-for-healthy-skin/
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 12, 2018 Date: Tuesday, June 12, 2018 1:12:22 PM Attachments: ATT00001.txt
In the News June 12, 2018
My Palm Beach Post – June 12 Dubin Breast Center: Doctor Turns Her Experience Into A Healing Center — Jan Tuckwood All warmth, hospitality and good cheer is happening inside a chemotherapy infusion room – in the Dubin Breast Center, founded by Dr. Eva Andersson-Dubin, at the Tisch Cancer Institute at the Mount Sinai Hospital. Her life’s mission, her passion, is serving women at the 7-year-old Dubin Breast Center, a spalike oasis in the middle of Mount Sinai. Dubin shares the story of her own breast cancer openly and matter-of-factly. In this serene enclave she has created, this place of vulnerability and compassion, there’s no need to hide. She touches base often with Elisa Port, MD, director of the Dubin Breast Center and Chief of Breast Surgery at the Mount Sinai Hospital. Like Dubin, Dr. Port is a blend of efficiency and empathy. - Eva Andersson-Dubin, MD, Founder, The Dubin Breast Center, Tisch Cancer Institute, The Mount Sinai Hospital - Elisa Port, MD, FACS, Director of the Dubin Breast Center and Chief of Breast Surgery, The Mount Sinai Hospital Learn more: https://www.mypalmbeachpost.com/lifestyles/doctor- compassion/OdfKh4eL8ZIBI6KlsAuSbL/
United Press International – June 11 Study: Inexpensive Nasal Brush Test Can Diagnose Asthma — Allen Cone Researchers have developed a simple nasal brush test than can accurately identify mild to moderate asthma in a cheaper way than pulmonary diagnostics. The nasal brush – which works the way it sounds – can more easily and comfortably differentiate an asthma diagnosis from other respiratory conditions, including allergic rhinitis, smoking, upper respiratory infection and cystic fibrosis. Researchers at Mount Sinai published their findings on the new test in the journal Scientific Reports. "Mild to moderate asthma can be difficult to diagnose because symptoms change over time and can be complicated by other respiratory conditions,” said Supinda Bunyavanich, MD, MPH, associate professor of genetics and genomic sciences at the Icahn School of Medicine at Mount Sinai. "One of the most exciting components of this study is demonstrating the power of machine learning when applied to biomedical data," said Gaurav Pandy, PhD, assistant professor of genetics and genomic sciences at the Icahn School of Medicine at Mount Sinai. “We have the power of insights we didn't have many of in the past and that opens a window to an entirely new world of diagnostic tools and treatments." - Supinda Bunyavanich, MD, MPH, Associate Professor, Genetics and Genomic Sciences, Pediatrics, Icahn School of Medicine at Mount Sinai - Gaurav Pandey, PhD, Assistant Professor, Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai Learn more: https://www.upi.com/Health_News/2018/06/11/Study-Inexpensive-nasal-brush-test-can- diagnose-asthma/8131528743304/ Additional coverage: Science Daily https://www.sciencedaily.com/releases/2018/06/180611133429.htm Genetic Engineering & Biotechnology News https://www.genengnews.com/gen-news-highlights/nasal- brush-identifies-genetic-biomarker-of-asthma/81255909 Medical Xpress https://medicalxpress.com/news/2018-06-team-asthma-nasal.html Technology Networks https://www.technologynetworks.com/tn/news/nasal-brush-test-to-diagnose- asthma-304945 Medical Health News http://www.medicalhealthnews.net/bmount-sinaib-team-diagnoses-asthma-with- nasal-brush-test Med India https://www.medindia.net/news/nasal-brush-test-can-identify-mild-to-moderate-asthma- 180162-1.htm Stamford Advocate https://www.stamfordadvocate.com/business/press-releases/article/Mount-Sinai- Team-Diagnoses-Asthma-With-Nasal-12985583.php mySanAntonio https://www.mysanantonio.com/business/press-releases/article/Mount-Sinai-Team- Diagnoses-Asthma-With-Nasal-12985583.php NBC 12 News http://www.nbc12.com/story/38399092/mount-sinai-team-diagnoses-asthma-with-nasal- brush-test
MedicalResearch.com – June 11 Major Brain Networks With Altered Brain Function In Individuals With Addiction Identified – Marie Benz Rita Goldstein, PhD, professor of psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai, chief of Brain Imaging Core, and director of the neuropsychoimaging of addiction and related conditions research program, and Anna Zilverstand, PhD, assistant professor of psychiatry at the Icahn School of Medicine at Mount Sinai, found wide-spread impairments in brain function that were independent of the substance to which an individual was addicted. These alternation affected many important basic psychological processes, such as attention, learning, decision making or the ability to inhibit impulsive actions. - Rita Goldstein, PhD, Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai, Chief, Brain Imaging Core, Director, Neuropsychoimaging of Addiction and Related Conditions Research Program - Anna Zilverstand, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: https://medicalresearch.com/addiction/major-brain-networks-with-altered-brain-function-in- individuals-with-addiction-identified/42309/
Metro US – June 11 Can Humans Get Dog Flu? — Meagan Morris A study published recently in mBio found that influenza viruses from pigs – already known to transfer dangerous swine flu to humans – can “jump” into dogs, and evolve and then infect humans. "In our study, what we have found is another set of viruses that come from swine that are originally avian in origin, and now they are jumping into dogs and have been re-assorted with other viruses in dogs,” said study co-author, Adolfo Garcia-Sastre, PhD, director of the Global Health and Emerging Pathogens Institute and professor of microbiology, medicine and infectious diseases at the Icahn School of Medicine at Mount Sinai. "They are starting to interact with each other. This is very reminiscent of what happened in swine ten years before the H1N1 pandemic." - Adolfo Garcia-Sastre, PhD, Director, Global Health and Emerging Pathogens Institute, Professor, Microbiology, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: https://www.metro.us/body-and-mind/health/can-humans-get-dog-flu
The Atlanta Journal-Constitution – June 8 Baby Teeth Could Be Predictor Of Autism, Study Suggests — Najja Parker Scientists have determined there is no one cause of autism. In fact, there may be several, and a recent examination of baby teeth may have helped them identity another, according to a new report. Researchers from the Icahn School of Medicine at Mount Sinai recently conducted a study to determine how children metabolize metals. To do so, they examined the baby teeth of 200 twins in Sweden. They uncovered that a new layer of tooth is formed each day as kids develop in the womb and throughout early childhood. In each layer, the “growth rings” capture evidence of many of the chemicals and metals, including zinc and copper that naturally circulate in the body. They found that the zinc and copper cycles were abnormal in kids with autism. While copper and zinc levels naturally fluctuate, the length of the cycles were shorter and more irregular in kids with autism, compared to kids without it. - Paul Curtin, PhD, Assistant Professor, Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai Learn more: https://www.ajc.com/news/world/baby-teeth-could-predictor-autism-study- suggests/kKb93gdfzw7jYC9geiC6gM/
The Washington Post – June 10 Latest Heart Valve Treatment Allows More Patients To Avoid Open-Heart Surgery — Marlene Cimons Transcatheter aortic valve replacement, or TAVR (also called TAVI, for transcatheter aortic valve implantation), currently is approved only for patients who cannot have open-heart surgery or for whom it would be risky. These include the elderly and frail, and people with complications such as kidney disease and coronary obstructive pulmonary disease. For many of them, TAVR has been lifesaving. “We’re very thankful to have this technology,” said Paul Stelzer, MD, professor of cardiovascular surgery at the Icahn School of Medicine at Mount Sinai. “Now we can do something for octogenarians and 90- year-olds we couldn’t help before.” Many experts believe that TAVR will become the first-line valve replacement treatment for almost everyone with aortic valve disease. - Paul Stelzer, MD, Professor, Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai Learn more: https://www.washingtonpost.com/national/health-science/latest-heart-valve-treatment- allows-more-patients-to-avoid-open-heart-surgery/2018/06/08/94199f14-6379-11e8-a768- ed043e33f1dc_story.html?noredirect=on&utm_term=.3787e8a19c3c
Medscape – June 12 $200K Saved With First-Line Docetaxel For Prostate Cancer — Nick Mulcahy Two systemic drugs for the treatment of newly diagnosed metastatic prostate cancer, which have comparable overall survival benefits, have hugely different costs, according to a new cost-effectiveness modeling analysis. Bobby Liaw, MD, assistant professor of medicine, hematology and medical oncology at the Icahn School of Medicine at Mount Sinai, said the new findings are not a “big surprise,” given that one drug is still on patent. Dr. Liaw said he does not talk about differences in cost-effectiveness between these drugs with patients "unless it is something a patient wants to discuss." He keeps the conversation to clinical issues, such as mode of administration, side effects, tolerability, duration of treatment, how each agent might affect comorbidities, and drug interactions. - Bobby Liaw, MD, Assistant Professor, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai Learn more: https://www.medscape.com/viewarticle/897928
Medscape – June 8 Internal Medicine Trainees, Especially Women, Put Off By Cardiology — Patrice Wendling In perhaps the most upfront, in-your-face look thus far, a series of papers published this week examines the obstacles facing women as well as men when pursuing a career in cardiology. The present survey, from the ACC’s Women in Cardiology Council and its Task Force on Diversity and Inclusion, finds that latest generation of physicians not choosing cardiology, citing adverse job conditions, interference with family life, and a lack of diversity as the top reasons. Roxana Mehran, MD, professor of medicine, cardiology, population health science and policy, and director of interventional cardiovascular research and clinical trials at the Icahn School of Medicine at Mount Sinai, said "I do not know of a single woman who has trained in cardiology and chosen interventional cardiology as her career who has not faced some level of sexual harassment or misconduct.” She added, "This is not hyperbole. Women have been underrepresented, underestimated, and undervalued for many long years — and I have not started on the salary gap." - Roxana Mehran, MD, Professor, Medicine, Cardiology, Population Health Science and Policy, Director, Interventional Cardiovascular Research and Clinical Trials, Zena and Michael A. Weiner Cardiovascular Institute, Icahn School of Medicine at Mount Sinai Learn more: https://www.medscape.com/viewarticle/897859
Big Think – June 11 Study Finds Mysterious Link Between Food Allergies And Autism — Stephen Johnson A new study reveals a link between food allergies and autism, though many questions remain. The study showed 11.25 percent of American children diagnosed with autism spectrum disorder (ASD) also have a food allergy, more than double the 4.25 percent of kids without ASD who suffer from a food allergy. Some medical professionals say parents shouldn’t overreact to the new study. “I wouldn’t want people to misinterpret this to say that a food allergy is causing autism,” said Scott Sicherer, MD, professor of pediatrics, allergy and immunology and chief of the division of allergy and immunology at the Jaffe Food Allergy Institute at the Icahn School of Medicine at Mount Sinai. - Scott Sicherer, MD, Professor, Pediatrics, Allergy and Immunology, Chief, Division of Allergy and Immunology, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai Learn more: http://bigthink.com/stephen-johnson/study-finds-mysterious-link-between-food-allergies- and-autism
Street Insider – June 11 CryoLife Announces Publication Of An On-X Aortic Heart Valve PROACT Study CryoLife, Inc., a leading cardiac and vascular surgery company focused on aortic disease, announced the publication of a clinical study entitled “Anticoagulation and Antiplatelet Strategies After On-X Mechanical Aortic Valve Replacement” in the Journal of the American College of Cardiology. John D. Puskas, MD, site chair of cardiovascular surgery at Mount Sinai St. Luke’s and Mount Sinai West, and international principal investigator for the PROACT trial, said, “We are honored that the Journal of American College of Cardiology has recognized our clinical work in their publication. Our findings support an important lower warfarin threshold advantage specifically for the On-X valve, which decreases the risks and health concerns associated with long-term anticoagulation.” - John D. Puskas, MD, Site Chair, Cardiovascular Surgery, Mount Sinai St. Luke’s, Mount Sinai West, Mount Sinai Beth Israel, Professor, Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai Learn more: https://www.streetinsider.com/Corporate+News/CryoLife+%28CRY%29+Announces+Publication+of+On- X+Aortic+Heart+Valve+PROACT+Study/14295455.html
CNBC News – June 11 Fitbit Wants To Help Kids Move More, And Investors Love It — Angelica LaVito Fitbit is looking to a new generation for growth. The company launched its new fitness tracker, Fitbit Ace, for children 8 years old and up on Monday. It wants to encourage children to move more. It also hopes appealing to a new audience will help it grown again. Fitbit also wants to help promote healthy behaviors from childhood. Abby Allen, MD, assistant professor of orthopedics and pediatrics at the Icahn School of Medicine at Mount Sinai and chief of pediatric orthopedic surgery for the Mount Sinai Health System said anything that instills the concept of a healthy lifestyle at a young age will likely carry into adulthood. “I cannot even begin to go into the possible benefits of building healthy habits, it would take too long.” - Abby Allen, MD, Assistant Professor, Orthopedics, Pediatrics, Icahn School of Medicine at Mount Sinai, Chief, Pediatric Orthopedic Surgery, Mount Sinai Health System Learn more: https://www.cnbc.com/2018/06/11/fitbits-stock-soars-after-launching-fitbit-ace-childrens- product.html
Newsweek – June 11 Hearing Loss In Children Linked To Secondhand Smoke Exposure, New Study Finds — Dana Dovey New research from Japan has revealed that exposure to smoking, both in utero and in the first few months of a child’s life, is associated with higher prevalence of hearing impairment. Although the study cannot prove that cigarette smoke exposure was the direct cause of the children’s hearing impairment, the researchers did note that preventing this exposure was a clear way to reduce the children’s risk. Karen Wilson, MD, MPH, professor of pediatrics, the Debra and Leon Black Division Chief of general pediatrics and vice-chair for clinical and translational research for the department of pediatrics at the Icahn School of Medicine at Mount Sinai, said she was not surprised by the results, although this is the first time she had seen such an association. Hearing is important for language development and learning, and if these impairments are not caught and reversed early on, they could interfere with a child’s ability to learn, Dr. Wilson noted. - Karen M. Wilson, MD, MPH, Professor, Pediatrics, Debra and Leon Black Division Chief, General Pediatrics, Vice-Chair, Clinical and Translational Research, Department of Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://www.newsweek.com/hearing-loss-second-hand-smoke-ear-health-pediatrics-971038
Self Magazine – June 11 9 Things People With Depression Wish You Knew About Living With The Condition — Korin Miller Discussions of mental health care have taken front stage following the loss last week of Kate Spade and Anthony Bourdain, both of whom died by suicide. Although suicide is a complex issue, mental illness – especially depression – is a major risk factor, according to the Centers for Disease Control and Prevention. It’s important to ask a loved one who has depression how they’re doing, and to keep asking and checking in, said Igor Galynker, MD, professor of psychiatry at the Icahn School of Medicine at Mount Sinai and chair of psychiatry research at Mount Sinai Beth Israel. Taking the initiative to let them know that you care, and that you’re there if they want to talk, can speak volumes, he said. - Igor Galynker, MD, Professor, Psychiatry, Icahn School of Medicine at Mount Sinai, Associate Chairman, Psychiatry Research, Mount Sinai Beth Israel Learn more: https://www.self.com/story/reality-of-depression-twitter Additional coverage: Yahoo News https://www.yahoo.com/lifestyle/9-things-people-depression-wish-225206432.html
She Knows – June 12 Signs Of Cervical Cancer You Might Miss— Elizabeth Yuko Before the Pap test became a part of the routine OB-GYN appointment, cervical cancer was one of the leading causes of death of American women according to the American Cancer Society. But even today, the ACS estimates that about 13,240 new cases of invasive cervical cancer will be diagnosed, and about 4,170 people will die from it. Stephanie Blank, MD, a professor of gynecologic oncology at the Icahn School of Medicine at Mount Sinai and director of women’s health at Mount Sinai Chelsea Center, discusses the signs and symptoms we should look for. According to Dr. Blank, one of the main signs of cervical cancer is abnormal bleeding after sex and between menstrual periods. If you’re experiencing these symptoms, she said you should see a doctor for an exam. - Stephanie V. Blank, MD, Professor in the Division of Gynecologic Oncology, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, and Director of Women's Health, Mount Sinai Downtown- Chelsea Center Learn more: http://www.sheknows.com/health-and-wellness/articles/1139843/cervical-cancer-signs
Cheat Sheet – June 11 Summertime Safety: Life-Saving Facts About Sunscreen You Need To Know — Mandi Kerr Summertime means different things to different people. But one thing summer should mean for everyone is sun protection, namely sunscreen. “SPF 30 blocks out about 97 percent of UV rays,” said Francesca Fusco, MD, assistant clinical professor of dermatology at the Icahn School of Medicine at Mount Sinai. “SPF 15 block out only 93 percent, and SPF 50 blocks out 98 percent of UV rays. When in doubt, reach for SPF 50. And don’t bother with SPF 2-4, it’s like applying body lotion.” - Francesca J. Fusco, MD, Assistant Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: https://www.cheatsheet.com/health-fitness/summertime-safety-life-saving-facts-about- sunscreen-you-need-to-know.html/?a=viewall
Cosmopolitan Magazine – June 8 How To Feel Better Faster When Belly Bloat Strikes — Elizabeth Narins Bloating has so many triggers that occasional flare ups are difficult to sidestep. “It’s normal to get a little abdominal distention after eating,” said Michelle Cohen, MD, assistant professor of gastroenterology at the Icahn School of Medicine at Mount Sinai. “But sometimes it can be painful and uncomfortable, and the success of the treatment depends on properly identifying the cause.” - Michelle Cohen, MD, Assistant Professor, Gastroenterology, Icahn School of Medicine at Mount Sinai Learn more: https://www.cosmopolitan.com/health-fitness/advice/g2972/how-to-beat-bloating/
AOL News – June 11 Already Sunburnt? Here’s What Dermatologists Would Do — Jenn Sinrich The best way to prevent sunburn is to stay out of the sun – but we all make mistakes. Top dermatologists share their tips for managing the pain, redness, and peeling. At the first opportunity, apply a cool compress lightly to your skin, allowing the heat to evaporate. Ice is great, but Joshua Zeichner, MD, assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai and director of cosmetic and clinical research in dermatology at The Mount Sinai Hospital, suggests a milk compress is even better. “Proteins in the milk help cool and soothe the skin,” he explained. “Mix skim milk and ice cubes in a bowel and then soak a washcloth in it and apply to the skin for 10 minutes.” - Joshua Zeichner, MD, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research in Dermatology, The Mount Sinai Hospital Learn more: https://www.aol.com/article/lifestyle/2018/06/11/already-sunburnt-heres-what- dermatologists-would-do/23456413/
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200
From: ITNDaily Subject: Mount Sinai In The News - June 13, 2018 Date: Wednesday, June 13, 2018 1:22:05 PM Attachments: ATT00001.txt
In the News June 13, 2018
MedicalResearch.com – June 12 New Test Can Identify Asthma With Nasal Brush Biomarker—Marie Benz In this study, we report on an accurate asthma biomarker we have developed based on a simple nasal brush, said Supinda Bunyavanich, MD, MPH, associate professor of genetics and genomic sciences, and pediatrics at the Icahn School of Medicine at Mount Sinai. “This simple, inexpensive test is easy to collect in a doctor’s office and results are determined with basic follow-up data-analysis. The biomarker was identified using machine learning algorithms,” she explained. “We’re hopeful that further studies can help bring this test into primary care settings, transforming the ease and accuracy of diagnosing asthma and our ability as doctors to appropriately treat our patients.” - Supinda Bunyavanich, MD, MPH, Associate Professor, Genetics and Genomic Sciences, Pediatrics, Icahn School of Medicine at Mount Sinai - Gaurav Pandey, PhD, Assistant Professor, Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai Learn more: https://medicalresearch.com/asthma/new-test-can-identify-asthma-with-nasal-brush- biomarker/42331/ Additional coverage: New Atlas https://newatlas.com/nasal-brush-asthma/55008/ Medical Laboratory Observer https://www.mlo-online.com/mount-sinai-team-diagnoses-asthma-with- nasal-brush-test
MedPage Today – June 12 Drug Addiction Networks; New MS Biomarker; Sleep and Dementia — Judy George Specific impairments in six brain networks are linked to drug addiction behavior, reported researchers at the Icahn School of Medicine at Mount Sinai. Neuroimaging studies "suggest a crucial role of the habit network in phases of marked behavioral change, such as during the initiation of drug use and relapse," they wrote, consistent with theories that implicate this network when people transition from recreational drug use to compulsive drug-seeking behavior. - Rita Goldstein, PhD, Professor, Psychiatry, Neuroscience, Icahn School of Medicine at Mount Sinai, Chief, Brain Imaging Core, Director, Neuropsychoimaging of Addiction and Related Conditions Research Program - Anna Zilverstand, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: https://www.medpagetoday.com/neurology/generalneurology/73445
The Ophthalmologist – June 12 Rejuvenating Cataract Surgery With A Simple Device: miLoop — Sean Ianchulev, MD, MPH Microinterventional technology in surgery isn’t new; our colleagues in the cardiovascular and interventional radiology fields have been using microstents and similar devices for about 40 years, explained Sean Ianchulev, MD, MPH, professor of ophthalmology at the Icahn School of Medicine at Mount Sinai and director of the ophthalmic innovation and technology program at the New York Eye and Ear Infirmary of Mount Sinai. Nevertheless, in cataract surgery, we’re still using the capsulorhexis and chopping tools that we were using 20 years ago. I believed that it was time to rejuvenate this field, and so I developed miLOOP – a simple, low-cost device for microinterventional cataract surgery. The miLoop comprises a nitinol filament mounted on a pen-type actuator, and enables rapid non-thermal cutting of even the hardest cataracts without vibrational, laser, or heat energy, and no fluidics complications. - Sean Ianchulev, MD, MPH, Professor, Ophthalmology, Icahn School of Medicine at Mount Sinai, Director of the Ophthalmic Innovation and Technology Program, New York Eye and Ear Infirmary of Mount Sinai Learn more: https://theophthalmologist.com/issues/0618/what-goes-around/
Genetic & Engineering Biotechnology News – June 12 Addicted To Aggression? Brain Protein May Hold The Answer According to scientists at the Icahn School of Medicine at Mount Sinai and the Perelman School of Medicine at the University of Pennsylvania, ΔFosB expression has distinct roles in two different cell types in the nucleus accumbens (NAc)—regulating aggressive behavior and its rewarding qualities. The scientists published their work in the Journal of Neuroscience. Essentially, the scientists found that ΔFosB expression promotes aggressive behavior, effects that are dissociable from its effects on aggression reward. “This finding,” the scientists noted, “is a significant first step in identifying therapeutic targets for the reduction of aggressive behavior across a range of neuropsychiatric illnesses.” Scott Russo, PhD, associate professor of neuroscience at the Icahn School of Medicine at Mount Sinai, and colleagues found that higher levels of ΔFosB in NAc neurons were associated with more intense behaviors by aggressive mice defending their home cage from an intruder. - Scott J. Russo, PhD, Associate Professor, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: https://www.genengnews.com/gen-news-highlights/addicted-to-aggression-brain-protein- may-hold-the-answer/81255912 tctMD – June 12 Burden Of Anticoagulation Can Be Reduced In Some Patients With Mechanical Valves — L.A. McKeown Patients at high risk for thromboembolism who undergo aortic valve replacement with a mechanical valve can safely take less than the standard dose of warfarin after 3 months, according to results of the PROACT trial. The study also evaluated whether dual platelet therapy (DAPT) is effective for those at low risk of thromboembolism, but ultimately found that warfarin is still needed in these patients. “The fundamental importance of this trial is that it changes the calculus of risk and benefit for mechanical valves,” said the study’s lead author, John D. Puskas, MD, site chair of cardiovascular surgery at Mount Sinai St. Luke’s and Mount Sinai West, professor of cardiovascular surgery at the Icahn School of Medicine at Mount Sinai. - John D. Puskas, MD, Site Chair, Cardiovascular Surgery, Mount Sinai St. Luke’s, Mount Sinai West, Mount Sinai Beth Israel, Professor, Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai Learn more: https://www.tctmd.com/news/burden-anticoagulation-can-be-reduced-some-patients- mechanical-valves
Orthopedics This Week – June 13 Ankle Salvage Possible After Distal Tibial Nonunion — Tracey Romero Periarticular distal tibial nonunions can be tricky to treat, but Mount Sinai researchers have found that ankle-spacing bone transport can be an effective alternative to bone graft and arthrodesis. The study was published in the Foot and Ankle International. Ettore Vulcano, MD, assistant professor of orthopedics at the Icahn School of Medicine at Mount Sinai, and his colleagues evaluated radiographic and clinical outcomes of 21 patients who underwent ankle-sparing bone transport for periarticular distal tibial nonunions between January 2016 and July 2016. Dr. Vulcano concluded that the ankle-sparing bone transport technique was an effective alternative to bone graft and arthrodesis, and that is was even safe for use in patients with infected nonunions in close proximity to the ankle joint. - Ettore Vulcano, MD, Assistant Professor, Orthopedics, Icahn School of Medicine at Mount Sinai, Orthopaedic Surgeon, Mount Sinai West Learn more: https://ryortho.com/breaking/ankle-salvage-possible-after-distal-tibial-nonunion/
MedCity News – June 13 An Oncology Innovation Conference Where Health IT And Biotech Intersect — Stephanie Baum MedCity Converge is a conference on innovation in cancer treatment and precision medicine. The Philadelphia event brings together thought leaders across venture capital, providers, pharma, patient advocates, health IT, and the startup community. Joshua Brody, MD, assistant professor of medicine, hematology and medical oncology and director of the lymphoma immunotherapy program at the Icahn School of Medicine at Mount Sinai, will be the opening keynote speaker offering his perspective on the impact of immunotherapy and the hype that surrounds this innovative approach to cancer treatment. -Joshua Brody, MD, Assistant Professor, Medicine, Hematology and Medical Oncology, Director, Lymphoma Immunotherapy Program, Icahn School of Medicine at Mount Sinai Learn more: https://medcitynews.com/2018/06/medcity-converge-oncology-innovation-conference/
HealthDay – June 13 High Blood Pressure In Your 50s May Set Stage For Dementia — Dennis Thompson Elevated blood pressure in your 50s might raise your risk of developing dementia later in life, a new European study has found. People with a systolic blood pressure of 130 or more at age 50 were 45 percent more likely to be struck by dementia than people with lower blood pressure at the same age, researchers reported. Sam Gandy, MD, PhD, professor of neurology, psychiatry and associate director of the Alzheimer’s Disease Research Center at the Icahn School of Medicine at Mount Sinai, said there could be a point in the person’s life at which it’s too late to use high blood pressure as a mean of warding off dementia. The fact that no increased risk was found in people at 60 and 70 in this study is consistent with a paper released last year showing that higher blood pressure late in life can actually be protective against dementia, Dr. Gandy noted. Severe high blood pressure in the elderly should be treated, but doctors must approach such blood pressure control with a light touch, Dr. Gandy said. - Samuel Gandy, MD, PhD, Professor, Neurology, Psychiatry, Associate Director, Alzheimer’s Disease Research Center, Icahn School of Medicine at Mount Sinai, Director, The Mount Sinai Center for Cognitive Health and NFL Neurological Care Learn more: https://consumer.healthday.com/cardiovascular-health-information-20/high-blood-pressure- health-news-358/high-blood-pressure-in-your-50s-may-set-stage-for-dementia-734794.html Additional coverage: U.S. News & World Report https://health.usnews.com/health-care/articles/2018-06-13/high-blood- pressure-in-your-50s-may-set-stage-for-dementia Newsmax Health https://www.newsmax.com/health/health-news/high-blood-pressure- hypertension/2018/06/13/id/865834/ Healthy Women http://www.healthywomen.org/content/article/high-blood-pressure-your-50s-may-set- stage-dementia Doctors Lounge https://www.doctorslounge.com/index.php/news/hd/81142
Good Housekeeping – June 12 Three Women Share The Moment They Knew They Had Depression, And How They Moved Forward — Meryl Davids Landau The symptoms of depression aren’t always as obvious as feeling hopeless and suicidal. While drugs and therapy can be lifelines, lifestyle changes can significantly help in the treatment of mild or moderate depression. Many women with major depression may also have other issues, such as anxiety, substance abuse problems, eating disorders or ADHD, said James Murrough, MD, assistant professor of psychiatry, neuroscience and director of the Mood and Anxiety Disorders Program at the Icahn School of Medicine at Mount Sinai. Typically each condition is treated separately, “but sometimes treating one can help fix the other,” he added. - James Murrough, MD, Assistant Professor, Psychiatry, Neuroscience, Director, Mood and Anxiety Disorders Program, Icahn School of Medicine at Mount Sinai Learn more: https://www.goodhousekeeping.com/health/a21287862/women-depression-stories/
Greatist – June 12 The Beginner’s Guide To Better Gut Health — Sabrina Weiss and Nick English Recent research has shown that our belly bacteria have an incredible impact on everything from fat loss and inflammation levels to perhaps even our susceptibility to depression and anxiety. Each day brings new findings about how the bacteria in our gastrointestinal tract affect systems throughout the body. "The notion of optimal digestive health can't be compared from one person to another,” said Pascale M. White, MD, assistant professor of medicine and director of the gastroenterology clinic at the Icahn School of Medicine at Mount Sinai. “Everyone has their own baseline.” Other signs of intestinal issues are increased bloating, heartburn, or stomach pain. - Pascale M. White, MD, Assistant Professor, Medicine, Director, GI Fellows Clinic, The Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai Learn more: https://greatist.com/live/good-gut-health
News Medical & Life Sciences – June 13 Dermatologists Gives Tips To Safely Use Stick And Spray Sunscreen Sunscreen is a vital tool in the fight against skin cancer, including melanoma, the deadliest form. Research suggests that daily sunscreen use, when used correctly, could significantly cut the incidence of melanoma. "Sticks are easy for under the eyes and the backs of the hands, while spray sunscreens are often easier to apply on children," said Debra Wattenberg, MD, assistant clinical professor of dermatology at the Icahn School of Medicine at Mount Sinai. "However, it's important to take precautions when using stick and spray sunscreens to ensure the best protection for you and your family." As with lotion sunscreens, Dr. Wattenberg recommends looking for sticks and sprays that are broad-spectrum, water- resistant and have an SPF of 30 or higher. "Broad spectrum" means that the sunscreen will protect against both types of harmful ultraviolet rays that can cause skin cancer, not just against the ones that cause sunburn. - Debra Wattenberg, MD, Assistant Clinical Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: https://greatist.com/live/good-gut-health
Men’s Health – June 12 7 Reasons Why You’re Experiencing Hair Loss, And How You Can Fix It — Emily Shiffer When you think about going bald, you’re probably thinking about male pattern baldness, a permanent and basically irreversible form of hair loss. Male pattern baldness tends to start with a receding hairline and thinning on the crown, which usually becomes more pronounced over time. But even if you’re losing more than that, male-pattern baldness might not necessarily be at play. In fact, there could be some temporary causes of baldness you should know about. "Alopecia areata is a condition in which your immune system attacks your hair-producing cells,” said Joshua Zeichner, MD, assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai and director of cosmetic and clinical research in dermatology at The Mount Sinai Hospital. "This leads to individual, round patches of hair loss. In some cases it may be severe and affect the entire scalp, or even the eyebrows or beard." You may also notice problems with your nails, such as pitting or white spots. If you think you may have alopecia areata visit your dermatologist to discuss your options, which include cortisone injections, said Dr. Zeichner. - Joshua Zeichner, MD, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research in Dermatology, The Mount Sinai Hospital Learn more: https://www.menshealth.com/health/g21286558/hair-loss-causes-and-treatment/
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 14, 2018 Date: Thursday, June 14, 2018 1:01:20 PM Attachments: ATT00001.txt
In the News June 14, 2018
Politico New York – June 14 Currently Incurable — Dan Goldberg An experimental model of HIV infection in mice has shown the virus causes learning and memory dysfunction, a cognitive disease that is now observed in about half of HIV infected people that worsens with age, according to a new study from Icahn School of Medicine at Mount Sinai researchers, which looks at data from 2012 to 2017. - Icahn School of Medicine at Mount Sinai Learn more: https://subscriber.politicopro.com/states/new-york/newsletters/politico-new-york-health-care/2018/06/14/optometrists-want- more-responsibilities-075487 (Subscription required)
Medscape – June 13 Infusion Type Doesn’t Affect Brain Outcomes In Pediatric DKA — Miriam E. Tucker In children presenting to the emergency department with diabetic ketoacidosis (DKA), neither the rate of administration nor the sodium chloride content of intravenous fluids appears to significantly influence neurologic outcomes, new research suggests. In contrast, "in the current study, which was performed at specialized centers with specialized staff, DKA–related brain injury appears unlikely to have been caused by the composition or rate of intravenous therapy. These conclusions are likely to generate discussion and lead to revision of current recommendations," wrote Mark A. Sperling, MD, professional lecturer in the department of pediatrics in the division of endocrinology, diabetes and bone disease at the Icahn School of Medicine at Mount Sinai, in an accompanying editorial. "DKA remains the leading cause of complications, death, and excessive healthcare utilization and costs in patients with type 1 diabetes," he stresses. - Mark A. Sperling, MD, Professional Lecturer, Department of Pediatrics, Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: https://www.medscape.com/viewarticle/898013 Additional coverage: HealthDay https://consumer.healthday.com/diabetes-information-10/type-i-diabetes-news-182/can-iv-fluids-harm-the-brain-of-those-with- serious-diabetes-complication-734831.html U.S. News & World Report https://health.usnews.com/health-care/articles/2018-06-13/can-iv-fluids-harm-the-brain-of-those-with-serious- diabetes-complication Health Magazine http://www.health.com/healthday/can-iv-fluids-harm-brain-those-serious-diabetes-complication Drugs.com https://www.drugs.com/news/can-iv-fluids-harm-brain-those-serious-diabetes-complication-74980.html? utm_source=ddc&utm_medium=rss&utm_campaign=Can+IV+Fluids+Harm+the+Brain+of+Those+With+Serious+Diabetes+Complication%3F Doctors Lounge https://www.doctorslounge.com/index.php/news/hd/81168 Medical Health News http://www.medicalhealthnews.net/infusion-type-doesn39t-affect-brain-outcomes-in-pediatric-dka
MedicalResearch.com – June 13 Neurobiology Links Aggressive Behavior and Addiction — Marie Benz There is increasing evidence that aggressive behavior might share key features with addiction, said Scott Russo, PhD, associate professor of neuroscience at the Icahn School of Medicine at Mount Sinai. “For example, aggressive mice develop positive associations with environmental cues associated with previous aggressive encounters (ie. they find aggression rewarding) and aggressive animals will work very hard to obtain access to a subordinate animal in order to attack them.” Aggression is an innate behavior shared across mammalian and non-mammalian species. In most cases it’s not pathological and rather serves an adaptive purpose allowing the individual to defend its territory or procedure resources. “This will be important to consider as we seek to find drugs that aide in the treatment of aggressive disorders,” he added. - Scott J. Russo, PhD, Associate Professor, Neuroscience, Icahn School of Medicine at Mount Sinai Learn more: https://medicalresearch.com/addiction/neurobiology-links-aggressive-behavior-and-addiction/42406/
The Irish Times – June 13 Gene Activity Offers A Window Into Kidney Transplants— Claire O’Connell Barbara Murphy, MD, dean of clinical integration and population health and chair of the department of medicine at the Icahn School of Medicine at Mount Sinai said, “We are developing new ways to predict when a transplanted kidney is likely to become damaged over the long term, so the person who received the kidney can be managed more effectively in order to prolong the survival of that organ. The hope then is they will not need another transplant as quickly or hopefully not at all.” She added that that idea is that you can then use this profile to treat the recipients who are at risk, with the aim of protecting the kidney and thereby preventing it from failing. - Barbara Murphy, MD, Dean, Clinical Integration and Population Health, Chair, Department of Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.irishtimes.com/news/science/gene-activity-offers-a-window-into-kidney-transplants-1.3522836
HealthDay – June 13 Why Are Statins Underused With Black Patients? — Dennis Thompson The color of a patient's skin appears to influence the medical care they receive for high cholesterol levels, a new study shows. Blacks are less likely than whites to receive appropriate treatment with cholesterol-lowering statins, the researchers report. The black patients in this study also had more high blood pressure, diabetes and hardening of the arteries, all of which are heart risk factors that would indicate the need for statin therapy, said Usman Baber, MD, assistant professor of medicine, cardiology, and director of clinical biometrics at the Cardiovascular Institute at the Icahn School of Medicine at Mount Sinai. "Therapeutic intensity does not match patient-level risk," said Dr. Baber, who was not involved with the study. "It's troubling to see there's a racial gap where African-American patients are even less likely than white patients to receive needed medicine." - Usman Baber, MD, Assistant Professor, Medicine, Cardiology, Director, Clinical Biometrics, Cardiovascular Institute, Icahn School of Medicine at Mount Sinai Learn more: https://consumer.healthday.com/cardiovascular-health-information-20/statins-news-780/why-are-statins-underused-with- black-patients-734827.html Additional coverage: US News & World Report https://health.usnews.com/health-care/articles/2018-06-13/why-are-statins-underused-with-black-patients Newsmax Health https://www.newsmax.com/health/health-news/statins-race-underused-factor/2018/06/14/id/866087/ Drugs.comhttps://www.drugs.com/news/why-statins-underused-black-patients-74974.html? utm_source=ddc&utm_medium=rss&utm_campaign=Why+Are+Statins+Underused+With+Black+Patients%3F Doctors Lounge https://www.doctorslounge.com/index.php/news/hd/81162
Healio – June 13 Aramchol Resolves NASH Without Worsening Of Fibrosis In Phase 2b Study — Talitha Bennett Galmed Pharmaceuticals announced topline results from a phase 2b study of Aramchol, a once-daily liver-targeted stearoyl-Coenzyme A desaturase 1 modulator designed for the treatment of nonalcoholic steatohepatitis, according to a press release. “Data from my laboratory submitted to an upcoming conference confirm by transcriptomic analysis a broad anti-fibrotic effect of Aramchol in fibrogenic hepatic stellate cells, which is complementary to the data seen in this phase 2b, biopsy-based clinical study,” Scott Friedman, MD, dean for therapeutic discovery and chief of the division of liver diseases at the Icahn School of Medicine at Mount Sinai said in the release. “In my view, these results, together with its safety and tolerability, place Aramchol among the leading frontline therapeutic candidates under investigation for NASH.” - Scott Friedman, MD, Dean, Therapeutic Discovery, Fishberg Professor, Medicine, Professor, Liver Diseases, Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, Chief, Liver Diseases, The Mount Sinai Health System Learn more: https://www.healio.com/hepatology/steatohepatitis-metabolic-liver-disease/news/online/%7B14dde2cd-9624-470c-9a93- 640c8d85189e%7D/aramchol-resolves-nash-without-worsening-of-fibrosis-in-phase-2b-study
MedPage Today – June 13 ‘Prehab’ Boosts Fitness Before Upper Gi Surgery — Charles Bankhead Patients who underwent prehabilitation prior to elective surgery for esophagogastric cancer had significantly better functional capacity before and after surgery, a small randomized trial showed. Though supportive of prehabilitation prior to cancer surgery, the results are not definitive because of issues related to the study design, said Raja Flores, MD, system chair of the department of thoracic surgery for the Mount Sinai Health System. "The idea of prehabilitation is very important. We learned that in the lung volume reduction study [for chronic obstructive pulmonary disease, COPD]. It showed that preoperative, prehabilitation really made a big difference in outcome. I think that will work in esophageal surgery, but this study, itself does not prove that. You need a bigger study with more patients to show that, but this study does point you in that direction," Dr. Flores told Medpage Today. - Raja Flores, MD, Steven and Ann Ames Professorship in Thoracic Surgery, Director, Thoracic Surgical Oncology Program, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, System Chair, Thoracic Surgery, Mount Sinai Health System Learn more: https://www.medpagetoday.com/hematologyoncology/othercancers/73486
Crain’s Health Pulse – June 14 Hospital For Special Surgery To Open Hudson Yards Outpatient Center — Jonathan LaMantia Hospital for Special Surgery will open a 15,000-square-foot clinic at 35 Hudson Yards next year as it seeks to attract new patients from among the companies and residents flocking to the complex. HSS isn't the first health care provider to see an expansion opportunity at the complex. Mount Sinai said in March that it would open an 18,000-square-foot concierge clinic at 55 Hudson Yards. It will cater exclusively to the employees of commercial tenants. - Mount Sinai Health System Learn more: http://www.crainsnewyork.com/article/20180614/PULSE/180619938/hospital-for-special-surgery-to-open-hudson-yards- outpatient-center
Medicine Net –June 13 High Blood Pressure in Your 50s May Set Stage for Dementia — Dennis Thompson Elevated blood pressure in your 50s might raise your risk of developing dementia later in life, a new European study has found.People with a systolic blood pressure of 130 or more at age 50 were 45 percent more likely to be struck by dementia than people with lower blood pressure at the same age, researchers reported Sam Gandy, MD, PhD, professor of neurology, psychiatry and associate director of the Alzheimer’s Disease Research Center at the Icahn School of Medicine at Mount Sinai said, “there could be a point in a person's life at which it's too late to use high blood pressure as a means of warding off dementia. The fact that no increased risk was found in people at 60 and 70 in this study is consistent with a paper released last year showing that higher blood pressure late in life can actually be protective against dementia,” Dr. Gandy noted. - Samuel Gandy, MD, PhD, Professor, Neurology, Psychiatry, Associate Director, Alzheimer’s Disease Research Center, Icahn School of Medicine at Mount Sinai, Director, The Mount Sinai Center for Cognitive Health and NFL Neurological Care Learn more: https://www.medicinenet.com/script/main/art.asp?articlekey=212964 Additional coverage: The Health Cast https://thehealthcast.com/alzheimers/high-blood-pressure-in-your-50s-may-set-stage-for-dementia/
Becker’s Hospital Review – June 14 8 Inspiring Quotes From 2018 Medical School Graduation Speeches — Emily Rappleye It's commencement season: Medical school students around the country are donning their graduation gowns, accomplished and ready to launch into the world of healthcare. With this new crop of physicians comes a new crop of inspiration, as relevant to new graduates as it is to those who have been on healthcare's front lines for decades. One inspiring quote comes from Timothy Shriver, PhD, chairman of the board, Special Olympics, to the graduates of the Icahn School of Medicine at Mount Sinai: "Graduates, you have an extraordinary gift and moment to celebrate. All I am asking you is lift us up, bring us together, restore our faith in each other. Restore our faith in the future. Restore our trust in the relationships that bind us together, more strongly than those that divide us. And remember, eyes wide open, eyes always open, because if you can see all of our wounds and if you can bring science and the spirit together, you can heal our bodies and our country too." - Icahn School of Medicine at Mount Sinai Learn more: https://www.beckershospitalreview.com/hospital-physician-relationships/8-inspiring-quotes-from-2018-medical-school- graduation-speeches.html
Reader’s Digest – June 14 21 Twitchy, Itchy Explanations for Why Your Scalp Itches — Lauren Cahn One of the explanations for why your scalp itches is because of an allergic reaction. If you recently colored your hair, it’s possible that you’re experiencing an allergy to the dye. This is true even if you’ve used the product before without incident. “If the hair color is temporary or semi-permanent it can be washed out,” explains Joshua Zeichner, MD, assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai and director of cosmetic and clinical research in dermatology at The Mount Sinai Hospital, “but if it’s a permanent dye, that presents a more challenging situation, although there are products on the market that can remove permanent dye altogether.” - Joshua Zeichner, MD, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research in Dermatology, The Mount Sinai Hospital Learn more: https://www.rd.com/health/conditions/itchy-scalp-reasons/
She Knows –June 13 Why Endometriosis Is So Difficult to Diagnose — Megan Fu In 2010, when Kristen McRobie was 21, she went to the emergency room with intense abdominal pain. Doctors thought it was appendicitis, but after multiple ultrasounds, a CT and an MRI, they concluded that a cyst had ruptured and recommended that McRobie see an endometriosis specialist. A few months, she got the diagnosis: stage 4 endometriosis. The worst case the doctor had ever seen. “I was lucky,” said McRobie. “Compared to other women, it wasn’t a drawn-out process to get me to that diagnosis.” And she’s right. It often takes multiple years and multiple doctors before endometriosis sufferers are correctly diagnosed. In fact, studies have shown that it can take seven to eight years, according to Tamara Kolev, MD, assistant professor of obstetrics and gynecology at Mount Sinai Beth Israel. - Tamara N Kolev, MD, Assistant Professor, Obstetrics, Gynecology and Reproductive Science, Mount Sinai Beth Israel, Icahn School of Medicine at Mount Sinai Learn more: https://www.sheknows.com/health-and-wellness/articles/1139146/why-endometriosis-is-so-difficult-to-diagnose
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200
From: ITNDaily Subject: Mount Sinai In The News - June 15, 2018 Date: Friday, June 15, 2018 10:33:59 AM Attachments: ATT00001.txt
In the News June 15, 2018
GenomeWeb – June 14 Mount Sinai Led Team Develops RNA Sequencing Classifier To Diagnose Mild, Moderate Asthma A group led by Mount Sinai researchers has used nasal brush collection and RNA sequencing (RNA-seq) to identify a genetic classifier for asthma. With further validation studies, the team believes its tool could lead to the development of a minimally invasive biomarker test that would cost only around $30. In the study published in Scientific Reports, the Mount Sinai-led team used RNA-seq to profile gene expression from nasal epithelial cells collected from 190 subjects with mild to moderate asthma, as well as 140 controls. Using a machine learning-based method, they developed an asthma classifier that was able to differentiate patients with and without mild-moderate asthma. Senior author, Supinda Bunyavanich, MD, MPH, associate professor of genetics and genomic sciences, and pediatrics at the Icahn School of Medicine at Mount Sinai, said that her colleagues used a nasal brush to swab patient airways containing nasal epithelial cells because of their ease of access and connection to the lungs. Dr. Bunyavanich envisions the test being used "at the clinical frontline," whether in the office or urgent care settings, where a clinician can perform nasal brushings. - Supinda Bunyavanich, MD, MPH, Associate Professor, Genetics and Genomic Sciences, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: https://www.genomeweb.com/sequencing/mt-sinai-led-team-develops-rna-sequencing- classifier-diagnose-mild-moderate-asthma#.WyLfyBsvxQI
Cataract & Refractive Surgery Today – June 14 DREAM Interpretations Abound Following Surprising Dry Eye Findings — Rochelle Nataloni Oral omega-3 supplements were no better than placebo in relieving the signs and symptoms of dry eye disease (DED) in a clinical trial funded by the National Eye Institute. The Dry Eye Assessment and Management (DREAM) study was the first large-scale, real-world randomized clinical trial to study the long-term efficacy and safety of omega-3 supplements for patients with symptomatic DED. Penny Asbell, MD, professor of ophthalmology and director of the Cornea Service and Refractive Surgery Center at the Icahn School of Medicine at Mount Sinai, was the chair of the DREAM study. “Our goal was to study people who say, ‘My eyes still bother me even though I am using various dry eye treatments. What else can I do?’ It is very rare in clinical practice to advise a patient to stop everything he or she is doing and use only omega-3.” - Penny Asbell, MD, Professor, Ophthalmology, Director, The Cornea Service and Refractive Surgery Center, Icahn School of Medicine at Mount Sinai Learn more: https://crstoday.com/articles/june-2018/dream-interpretations-abound-following-surprising- dry-eye-study-findings/
MobiHealth News – June 14 Studies Lend Credence To Click Therapeutics’ Digital Therapeutic For Depression—Dave Muoio The past month has seen a succession of publications offering support for Click Therapeutics’ digital offering for patients with major depressive disorder (MDD). The studies showed the therapeutic to reduce symptoms, pair well with the transcranial direct-current simulation, and invoke a clear neurobiological mechanism related to cognitive control and emotional processing. “The data from these studies combined are incredibly encouraging for [Emotional Faces Memory Task (EFMT)] as an effective treatment for MDD,” said Brain Iacoviello, PhD, director of scientific affairs at Click Therapeutics and assistant professor of psychiatry at the Icahn School of Medicine at Mount Sinai. “Not only do we observe symptom improvement in adults with MDD, and adults with medication resistant depression when combined with tDCS, but for the first time we have shown that EFMT can have the neuroplastic effects expected in key brain regions involved in MDD, and that these changes are associated with symptom improvement.” - Brian Iacoviello, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.mobihealthnews.com/content/studies-lend-credence-click-therapeutics-digital- therapeutic-depression
Reuters Health – June 14 Doctors Have Cost Concerns About Genetic Tests For Disease Risk— Lisa Rapaport While many primary care providers believe genetic tests to assess risk for common chronic diseases might prove useful in treating patients, a recent study also suggests they’re worried that steep out-of- pocket costs may limit who can be tested. “If insurance does not cover costs, this can further widen disparities in access to genetic testing by keeping them the purview of patients who have more resources,” said senior study author Carol Horowitz, MD, professor of medicine, general internal medicine, population health science and policy at the Icahn School of Medicine at Mount Sinai. “As it stands, low-income, minority patients are most likely to suffer from chronic diseases,” Dr. Horowitz added. “These priority populations should not be the last to benefit from advances in genetics, or it will just be another example of ways health systems can inadvertently widen the disparities so many of us are committed to eliminating.” - Carol R. Horowitz, MD, Professor, Population Health Science and Policy, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.reuters.com/article/us-health-genetics-screening/doctors-have-cost-concerns- about-genetic-tests-for-disease-risk-idUSKBN1JA308 Additional coverage: KFGO News http://kfgo.com/news/articles/2018/jun/14/doctors-have-cost-concerns-about-genetic-tests- for-disease-risk/
The Atlantic – June 14 The Neuroscientific Case For Facing Your Fears — Ed Yong A new study shows that mice have to remember their phobias if they are to lose them effectively. When people bring up old memories, the engram neurons fire up again. They also enter a brief period of instability, when the molecules that preserved the connections between them disappear and must be remade. This process known as reconsolidation, means that humans are partly reconstructing our memories every time they bring them to mind. And it means that the act of recollection creates a window of time in which memories can be updated, and fears can be unlearned. “That was the theory,” says Daniella Schiller, associate professor of neuroscience at the Icahn School of Medicine at Mount Sinai. “It’s been speculated, but [this new study] is one of the most direct demonstrations so far.” - Daniela Schiller, PhD, Associate Professor, Neuroscience, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: https://www.theatlantic.com/science/archive/2018/06/the-neuroscientific-case-for-facing- your-fears/562820/
Greatist – May X How Often Do You Really Need To Change Your Workout to Keep From Plateauing? — Shaun Dreisbach People like to say that around the six- to eight-week mark, your body adapts to whatever workout you’ve been doing and stops getting the same results. But what’s so special about that specific length of time? And is it really true? Turns out, not so much. “There’s nothing magical about that number. It’s a myth,” said Richard Wiel, Med, exercise physiologist and director of the Mount Sinai St. Luke’s Weight Loss Program. "The fact is that research-based guidelines on how often you need to vary your workout to avoid a plateau just don't exist." There are so many other variables, “how often you work out, what shape you’re in, how much weight you’re lifting – even genetics plays a role,” - Richard Weil, MEd, Exercise Physiologist, Director, Mount Sinai St. Luke’s Weight Loss Program Learn more: https://greatist.com/move/at-what-point-do-you-hit-a-workout-plateau
Allure Magazine – June 14 Bausch & Lomb’s New Lumify Eye Drops— Kaleigh Fasanella Bausch & Lomb’s new Lumify eye drops contain an active ingredient, brimonidine tartrate. This is not supposed to cause aforementioned rebound redness. "It's a selective decongestant that hasn't shown to cause any rebound redness or loss of effect over an eight-hour period," said Tal Raviv, MD, associate clinical professor of ophthalmology at the Icahn School of Medicine at Mount Sinai. "Most ophthalmologists and optometrists would always want to address the underlying cause of the red eye, but when no specific underlying cause is found, Lumify may be a good option," he added. - Tal Raviv, MD, Associate Clinical Professor, Ophthalmology, Icahn School of Medicine at Mount Sinai Learn more: https://www.allure.com/review/bausch-and-lomb-lumify-eye-drops-review-photos
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 18, 2018 Date: Monday, June 18, 2018 12:37:17 PM Attachments: ATT00001.txt
In the News June 18, 2018
The Hill – June 16 Can We Stop The Gun Violence Epidemic? Yes, By Treating It As A Health Crisis – Kenneth L. Davis, MD After each new episode in our nation’s worsening gun violence epidemic, the same two things happen: First, our screens and social media feeds are saturated with hauntingly familiar images — and then we’re told that it’s too soon to talk about gun laws. We need to break this cycle. Kenneth L. Davis, president and CEO of the Mount Sinai Health System writes, “For physicians, this is particularly poignant. While the rest of the country sees the television coverage from a distance, we see the trauma up close. Medical workers don’t have the luxury of becoming desensitized to the repetitive violence. Which is why we also know that the predictable, repetitive conversation — the misguided idea that it would be easier to address mental health than fix our insanely insufficient gun safety laws — must stop.” He added, “We need to treat gun violence like the health crisis it is. We should prevent gun deaths the same way we’ve prevented deaths from cigarette smoking, or car crashes, or curable diseases.” - Kenneth L. Davis, MD, President, CEO, Mount Sinai Health System Learn more: http://thehill.com/opinion/healthcare/392201-can-we-stop-the-gun-violence-epidemic-yes- by-treating-it-as-a-health
Medical Xpress – June 18 Intravenous Acetaminophen Has Limited Benefit For Colectomy Patients, Study Finds Intravenous (IV) acetaminophen is no more effective than oral acetaminophen for patients undergoing colorectal procedures, Mount Sinai researchers report in a first-of-its-kind study. These findings suggest that eliminating use of IV acetaminophen, which is much more expensive than its oral counterpart, may result in very significant cost savings for hospitals with no impact on the patient experience or outcomes. "With any new drug that is introduced to the U.S. market, it is very important to monitor how it is used and if this results in the desired outcomes. Our study results do not support routine use of IV acetaminophen," explained lead investigator Jashvant Poeran, MD, PhD, assistant professor of medicine, orthopedics, population health science and policy at the Icahn School of Medicine at Mount Sinai. The study team is currently addressing this same question in other types of surgery, such as hip, knee and shoulder replacement, and anticipates more findings in the near future. - Jashvant Poeran, MD, PhD, Assistant Professor, Population Health Science and Policy, Medicine, Orthopedics, Icahn School of Medicine at Mount Sinai Learn more: https://medicalxpress.com/news/2018-06-intravenous-acetaminophen-limited-benefit- colectomy.html
Nature – June 15 Cancer Researchers Target The Dormant Cells That Seed Tumors— Heidi Ledford After decades of designing drugs to kill rapidly dividing tumor cells, many cancer researchers are switching gears: targeting malignant cells that lie silent and scattered around the body, before they give rise to new tumors. Dormant cancer cells are rare, and they are difficult to sift from the trillions of normal cells in the body. For years, researchers lacked the tools to study them, said Julio Aguirre-Ghiso, PhD, professor of medicine, hematology, medical oncology, otolaryngology and oncological sciences at the Icahn School of Medicine at Mount Sinai. But that is beginning to change. From June 19-22, researchers will gather in Montreal, Canada, for what Dr. Aguirre-Ghiso says is the first meeting dedicated to these sleeper cancer cells. “The mass of investigators has reached a critical number,” he says. “And there is the realization that it’s an important clinical need.” - Julio Aguirre-Ghiso, PhD, Professor, Medicine, Hematology, Medical Oncology, Otolaryngology, Oncological Sciences, Icahn School of Medicine at Mount Sinai Learn more: https://www.nature.com/articles/d41586-018-05445-x
News 12 – June 15 Oceanside Man’s Injury Opens Eyes To New Safety Measures An Oceanside man’s injury prompted a Nassau softball team to take added safety measures and promote awareness across Long Island. Mark Brook nearly lost vision in his right eye last year after he was hit by a softball. Brook went to the New York Eye and Ear Infirmary of Mount Sinai and saw Meenakashi Gupta, MD, assistant professor of ophthalmology at the Icahn School of Medicine at Mount Sinai and co-director of teleretinal imaging at the New York Eye and Ear Infirmary of Mount Sinai. Dr. Gupta found that his retina was twisted and that he was in need of a complicated emergency surgery. Months later, Brook has made much progress in his recovery. He can see again and is back playing softball. The team is now wearing a facial mask on their batting helmets and protective eyewear. According to several medical websites, 40 percent of all sports injuries involve the face. The injuries are most often due to direct hits with a ball or player-to-player contact. - Meenakashi Gupta, MD, Assistant Professor, Ophthalmology, Icahn School of Medicine at Mount Sinai, Co-Director, Teleretinal Imaging, New York Eye and Ear Infirmary of Mount Sinai Learn more: http://www.news12.com/story/38427062/oceanside-mans-injury-opens-eyes-to-new-safety- measures
Futurity – June 15 Not All Alzheimer’s Damage Is The Same — Jim Dryden Researchers have discovered that Alzheimer’s disease damages different types of brain cells depending on the genes involved. Alzheimer’s disease implicates multiple genes. Some are linked to early-onset Alzheimer’s, a condition that develops in one’s 30s, 40s, and 50s, while others are associated with the more common late-onset form of the disease. Using a computerized method, researchers attempted to differentiate the effects of the genes and identify pathways that might be therapeutic targets. The researchers analyzed postmortem samples from the Mount Sinai Brain Brank, the Mayo Clinic Brain Bank, and from the Knight Alzheimer’s Disease Research Center at Washington University, of people with genetic mutations that led to early on-set Alzheimer’s. Using computerized methods to identify types of brain cells in tissue samples from deceased patients, the researchers found that populations of various brain cell types are different, depending on which genes led to the development of Alzheimer’s. - Mount Sinai Brain Bank Learn more: https://www.futurity.org/alzheimers-disease-genes-brain-cell-damage-1786192/
Healio: Cardiology Today – June 15 Lower Warfarin Dose Feasible After Surgical AVR With Mechanical Valve— Erik Swain Among patients who underwent surgical aortic valve replacement with a mechanical valve designed to be used with reduced anticoagulation therapy, reduced warfarin intensity did not lead to increased thrombotic risk, researchers reported. However, using dual antiplatelet therapy instead of anticoagulants after surgical AVR was associated with elevated risk for thromboembolism and valve thrombosis. At 8.8 years of follow-up, the low-risk arm of the study was terminated due to excess cerebral thromboembolic events in the DAPT group, John Puskas, MD, site chair of cardiovascular surgery at Mount Sinai St. Luke’s and Mount Sinai West, and professor of cardiovascular surgery at the Icahn School of Medicine at Mount Sinai, and colleagues wrote, noting there was no difference between the groups in bleeding or all- cause mortality. “These findings led the FDA to support an indication for use for the On-X valve in the aortic position with an INR of 1.5 to 2.0 plus 81 mg of aspirin after 3 postoperative months of standard warfarin therapy and aspirin 81 mg per day,” Dr. Puskas and colleagues wrote. - John D. Puskas, MD, Site Chair, Cardiovascular Surgery, Mount Sinai St. Luke’s, Mount Sinai West, Mount Sinai Beth Israel, Professor, Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai Learn more: https://www.healio.com/cardiology/surgery/news/online/%7Bddac709f-92fb-4d48-bff1- 26a35ff310c5%7D/lower-warfarin-dose-feasible-after-surgical-avr-with-mechanical-valve
Healio: Orthopedics Today – June 18 Ankle-Sparing Bone Transport Effective For Periarticular Distal Tibial Nonunions— Monica Jaramillo The ankle-sparing bone transport approach was effective for the treatment of periarticular distal tibial nonunions and was considered safe for patients with infected nonunions that were close to the ankle joint. “To date, no ideal treatment has been identified as no surgical procedure has a 100% long-term success,” said Ettore Vulcano, MD, assistant professor of orthopedics at the Icahn School of Medicine at Mount Sinai and orthopedic surgeon at Mount Sinai West. “What got me thinking about finding a different way to address this problem was that I noticed that patients with an osteochondral defect found on MRIs taken for other reasons with no ankle pain had no bone bruising or marrow edema on the MRI. I therefore thought of injecting calcium phosphate cement into the affected bone underlying the cartilage defect to get rid of that bone bruising. Surprisingly the procedure worked in over 90 percent of patients.” - Ettore Vulcano, MD, Assistant Professor, Orthopedics, Icahn School of Medicine at Mount Sinai, Orthopedic Surgeon, Mount Sinai West Learn more: https://www.healio.com/orthopedics/foot-ankle/news/online/%7B3b2c8fde-0d78-4d17-9fd3- b2519e9f5727%7D/ankle-sparing-bone-transport-effective-for-periarticular-distal-tibial-nonunions
CBS News Denver – June 16 Boulder Woman Credits Doctor For Giving Her Chance To Ride Again — Michael Abeyta Sarah Guenther loves to move, and she’s happiest when she’s working up a sweat. That’s why she decided to move from New York City to Colorado; to be among the natural beauty of the state as she goes to school and races triathlons. Right before she packed up, her training hit a roadblock during a workout in Central Park. She was cut off by a tourist who was not paying attention, and instead of swerving she hit both of her brakes and flew over her handlebars. She had a lot of road rash and needed 150 stiches in her face. Worst of all she had swelling in her neck which cause severe neck and shoulder pain. Saad Chaudhary, MD, associate director of the spine surgery fellowship and assistant professor in the department of orthopedic surgery at the Icahn School of Medicine at Mount Sinai, remembers when he first saw her. “She had a very hard time lifting up her shoulder. She had a hard time even bending up her elbow to do basic tasks,” he said. Usually a spinal fusion would be performed to relieve the pressure placed on her disk, but she and Dr. Chaudhary were concerned about losing range of motion. “So the procedure we selected for her was to again, decompress and remove the disk” said Dr. Chaudhary. “But as opposed to fusing or locking that area we placed a mobile part or mobile disk in there that would allow her to retain her normal range of motion.” - Saad B. Chaudhary, MD, MBA, Minimally Invasive & Complex Spine Surgery, The Mount Sinai Hospital, Associate Director, Spine Surgery Fellowship, Assistant Professor, Department of Orthopedic Surgery, Icahn School of Medicine at Mount Sinai Learn more: http://denver.cbslocal.com/2018/06/16/woman-credits-doctor-bike/ Additional coverage: MSN News https://www.msn.com/en-us/video/movies/boulder-woman-credits-doctor-for-giving-her- the-chance-to-ride-again/vp-AAyJN9L
Self Magazine – June 15 These Common Drugs Have Been Linked To Depression, But It’s Complicated — Korin Miller A new study highlights the fact that there are many prescription drugs on the market that have been linked to depression – and many people may be taking at least one of them. The study, which was published in JAMA, found that more than one-third of Americans are taking at least one prescription drug that lists depression as a potential side effect. On top of that, people who take those drugs have higher rates of depression than those who don’t. If you’re taking one of the drugs included in this study, it’s good to have an understanding of the symptoms of depression, said Igor Galynker, MD, professor of psychiatry at the Icahn School of Medicine at Mount Sinai and associate chairman of psychiatry research at Mount Sinai Beth Israel. That includes a persistent feeling of sadness; feelings of hopelessness, guilt, worthlessness, and helplessness; a loss of interest in doing things; fatigue; difficulty concentrating; insomnia; low appetite; restlessness or irritability; unexplained aches and pains; and thoughts of death or suicide. - Igor Galynker, MD, Professor, Psychiatry, Icahn School of Medicine at Mount Sinai, Associate Chairman, Psychiatry Research, Mount Sinai Beth Israel Learn more: https://www.self.com/story/common-drugs-linked-to-depression
U.S. News & World Report – June 15 A New Shingles Vaccine: Prepare For Harsher Side Effects — Lisa Esposito If you’re 50 or older, you're advised to get immunized to protect yourself from shingles. If the new shingles vaccine made you feel worse than you expected, you're not alone. Skin rash, joint pain, flu-like symptoms, headaches and fatigue are some complaints from patients who've had the recently approved Shingrix vaccine. Side effects can last two or three days, and the injection site in the upper arm can hurt. "Part of the problem is that health care providers may not have fully understood the instructions of administration," said Talia Swartz, MD, PhD, assistant professor of medicine and infectious diseases at the Icahn School of Medicine at Mount Sinai. Providers can refer to the website of Shingrix manufacturer GSK for complete administration instructions for this relatively unfamiliar vaccine, Dr. Swartz suggested. "As providers are more comfortable with it, I believe the administration errors would be expected to be reduced," she said. - Talia Swartz, MD, PhD, Assistant Professor, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: https://health.usnews.com/health-care/patient-advice/articles/2018-06-15/a-new-shingles- vaccine-prepare-for-harsher-side-effects
HealthDay – June 18 Today’s Sleepy Teens May Be Tomorrow’s Heart Patients — Dennis Thompson Most kids don't get enough sleep, and that may put them on a path to future heart trouble, a new study finds. Young teens who slept less than seven hours a night tended to have more body fat, elevated blood pressure and less healthy cholesterol levels – all bad for the heart, researchers say. "I was really struck by how little these adolescents are sleeping," said Andrew Varga, MD, PhD, assistant professor of medicine, pulmonary, critical care and sleep medicine at the Icahn School of Medicine at Mount Sinai. "It's not totally surprising, given what I know about kids and their habits, but you would think there would be some drive for these kids to sleep more because they have a high sleep need." - Andrew W. Varga, MD, PhD, Assistant Professor, Medicine, Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://consumer.healthday.com/sleep-disorder-information-33/misc-sleep-problems-news- 626/today-s-sleepy-teens-may-be-tomorrow-s-heart-patients-734917.html Additional coverage: Doctors Lounge https://www.doctorslounge.com/index.php/news/hd/81234
Televisa News – June 12 Suicides Of Two Celebrities Impact New Yorkers The suicides of Kate Spade and Anthony Bourdain have impacted many New Yorkers. Hansel Arroyo, MD, psychiatry director of Mount Sinai’s Center for Transgender Medicine and Surgery and associate professor of psychiatry at the Icahn School of Medicine at Mount Sinai weighs in. - Hansel Arroyo, MD, Psychiatry Director, Mount Sinai’s Center for Transgender Medicine and Surgery, Associate Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: https://noticieros.televisa.com/videos/suicidios-dos-celebridades-impactan-neoyorquinos//
Men’s Health – June 15 The Only Self-Care Strategy You’ll Ever Need— Emily Abbate Whether you’re an endurance junkie or a gym rat, here are practical ways to incorporate self-care into your regular routine for a more optimized lifestyle. When the world is your oyster, it’s easy to see the exciting adventure opportunity everywhere and anywhere, from your backyard to a highway rest stop. Sometimes, what your body really needs is simply rest. “Knowing when to rest your body and mind is an incredibly important part of maintaining a healthy routine,” said Brian Mikolasko, MD, an internist at the Icahn School of Medicine at Mount Sinai. “Without time to recover from sustained or intense activity, our bodies and minds cannot grow stronger from the positive stresses we put on them. Rather, excess exertion sets us up for mental fatigue and routine disrupting injuries. Even the most elite athletes know that achieving optimum performance requires a cycle with well-timed rest.” - Brian Mikolasko, MD, Internist, Icahn School of Medicine at Mount Sinai Learn more: https://www.menshealth.com/health/a20649572/best-self-care-routines-for-men/
Self Magazine – June 15 Six Ways Your Mattress Could Be Negatively Affecting Your Health— Nina Bahadur When it comes to your mattress, adequate spine support is simply nonnegotiable. Your spine—which is made up of interlocking bones called vertebrae—has some natural curves in it. You want to sleep in a way that supports those natural curves. “When you sag, your spine gets bent, and that can lead to discomfort,” said David Rapoport, MD, director of the sleep medicine research program at the Icahn School of Medicine at Mount Sinai. “If you’re waking up sore and achy, there is good reason to believe your mattress is mismatched to what you need.” - David Rapoport, MD, Professor, Medicine, Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, Director of the Sleep Medicine Research Program at Mount Sinai Learn more: https://www.self.com/story/mattress-health-effects
Self Magazine – June 15 Six Eczema Symptoms You Should Bring Up With Your Derm— Korin Miller Eczema symptoms are hard to ignore. But, depending on the severity of your eczema symptoms, you might think you just have problematic skin – no an actual condition that you can manage with the help of a doctor. For many people, itching is the most bothersome symptom of eczema, said Gary Goldenberg, MD, assistant professor of dermatology and pathology at the Icahn School of Medicine at Mount Sinai and director of the dermatology faculty practice at The Mount Sinai Hospital. Though it can happen at any time, it’s often worse at night because you have no other distractions from the itchy feeling when you’re trying to fall asleep, said Joshua Zeichner, MD, assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai and director of cosmetic and clinical research in dermatology at the Mount Sinai Hospital. - Gary Goldenberg, MD, Assistant Professor, Dermatology, Pathology, Icahn School of Medicine at Mount Sinai, Director, Dermatology Faculty Practice, The Mount Sinai Hospital - Joshua Zeichner, MD, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research in Dermatology, The Mount Sinai Hospital Learn more: https://www.self.com/story/eczema-symptoms-to-know
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 19, 2018 Date: Tuesday, June 19, 2018 1:43:42 PM Attachments: ATT00001.txt
In the News June 19, 2018
Science Daily –June 18 Increased Risk Of Birth Defects In Babies After First-Trimester Exposure To Lithium Researchers from the Icahn School of Medicine at Mount Sinai found an elevated risk of major congenital malformations in fetuses after first-trimester exposure to lithium, in the largest study ever to examine the risk of birth defects in lithium-exposed babies. Lithium therapy is widely recommended as a first-line treatment for bipolar disorder, which affects approximately 2 percent of the world's population. Lithium helps to prevent severe depression and mania. In the United States, bipolar disorder is more commonly treated with anti-psychotic drugs instead of lithium. "Women should be informed on malformation risk in first-trimester exposed infants, but also about very high relapse risks for mental illness both during pregnancy and during the postpartum period," said the study's senior author, Veerle Bergink, MD, PhD, professor of psychiatry and of obstetrics, gynecology, and reproductive science, Icahn School of Medicine at Mount Sinai. "Given the well-documented effectiveness of lithium in reducing relapse in the perinatal period, some important clinical considerations are either to continue lithium in a lower dose during the first trimester or to restart lithium after the first trimester or immediately postpartum." - Veerle Bergink, MD, PhD, Senior Faculty, Departments of Psychiatry and Obstetrics, Gynecology and Reproductive Science at Icahn School of Medicine at Mount Sinai Learn more: https://www.sciencedaily.com/releases/2018/06/180618222457.htm Additional coverage: Healio: https://www.healio.com/psychiatry/bipolar-disorder/news/online/%7B824c39cf-4245-410a-be65- 379c937463c3%7D/first-trimester-lithium-exposure-increases-risk-for-birth-defects US News: https://health.usnews.com/health-care/articles/2018-06-18/psychiatric-drug-lithium-tied-to- birth-defect-risk Medical Xpress: https://medicalxpress.com/news/2018-06-birth-defects-babies-first-trimester- exposure.html Health.com: http://www.health.com/healthday/psychiatric-drug-lithium-tied-birth-defect-risk Healthday: : https://consumer.healthday.com/mental-health-information-25/bipolar-affective-disorder- news-60/psychiatric-drug-lithium-tied-to-birth-defect-risk-734958.html The Independent: https://www.independent.co.uk/news/health/lithium-bipolar-birth-defects-mood- disorders-major-depression-malformation-study-a8405036.html
Washington Post – June 19 The Growing Case Against IV Tylenol, Once Seen As A Solution To The Opioid Crisis — Carolyn Y. Johnson In the midst of the opioid crisis, Boston Medical Center added an intravenous version of Tylenol to its arsenal of drugs for pain management. But IV Tylenol was expensive, and after drugmaker Mallinckrodt Pharmaceuticals increased the price, the hospital projected it was on track to spend $750,000 in 2015 on acetaminophen (the active ingredient in Tylenol) in injectable form. The study being published in the July issue of the journal Anesthesiology, found that IV acetaminophen appeared no better in reducing opioid use than taking the medicine orally. “It just seems very often, physicians have magical thinking about a new preparation of an old drug,” said Andrew Leibowitz, MD, professor and system chair of the department of anesthesiology, perioperative and pain medicine at the Icahn School of Medicine at Mount Sinai, who co-authored the study. “Doctors do seem, in general when a patient is in the hospital, to favor IV medications as a knee-jerk reflex, even when equally effective oral medications are available.” - Andrew B Leibowitz, M.D, Professor and System Chair, Department of Anesthesiology, Perioperative and Pain Medicine, Professor, Surgery, Icahn School of Medicine at Mount Sinai Learn more: https://www.washingtonpost.com/news/wonk/wp/2018/06/19/the-growing-case-against-iv- tylenol-once-seen-as-a-solution-to-the-opioid-crisis/?noredirect=on&utm_term=.d33de1623fef
Spectrum News – June 19 Genetic Testing, Counseling Crucial In People With Developmental Delay -- Dr. Silvia De Rubeis and Dr. Paige Siper Brock was admitted to the hospital when he was 3 weeks old due to failure to thrive. In addition to poor weight gain and significant feeding difficulties, his reflexes had declined. Brock’s pediatrician recommended hospitalization to expedite the testing process, as it was clear he required multidisciplinary expertise. A clinical geneticist was on rotation during Brock’s hospital stay and identified a large deletion spanning FOXP1. The gene is implicated in a neurodevelopmental condition called FOXP1 syndrome. In his search for information, Brock’s father found a webinar on FOXP1 syndrome hosted by the Seaver Autism Center at the Icahn School of Medicine at Mount Sinai. We specialize in comprehensive clinical and genetic assessment of individuals with autism and related conditions, including FOXP1 syndrome. Genetic testing can be critical to a child’s health and development. If we do not know a child has a FOXP1 disruption, treatable medical issues may go undetected. Identifying a genetic disruption may give us a chance to begin intervention before delays emerge. Brock, for example, began physical therapy and feeding therapy before 6 months of age. Positive genetic findings can also inform research — for example, for creating cell and animal models of developmental conditions and for developing treatments, as we do at our center. - Silvia De Rubeis, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine at Mount Sinai, Psychiatrist, The Seaver Autism Center for Research and Treatment at Mount Sinai - Paige M. Siper, PhD, Assistant Professor, Psychiatry, Chief Psychologist, The Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai Learn more: https://www.spectrumnews.org/opinion/viewpoint/genetic-testing-counseling-crucial- people-developmental-delay/
Healio – June 19 IV Acetaminophen Shows Limited Benefits After Colorectal Surgery — Wasserman I, et al Intravenous acetaminophen was no more effective than oral delivery for patients who underwent colectomy, being associated with only marginal reductions in opioid use after surgery, according to research published in Anesthesiology. Although IV acetaminophen was used in only a minority of patients, these findings suggest its use should be eliminated, as it is much more expensive than its orally delivered counterpart, according to Jashvant Poeran, MD, PhD, assistant professor of population health and health science policy at the Icahn School of Medicine at Mount Sinai, and colleagues. This could lead to significant cost-savings for hospitals without impacting patient outcomes, they added. “With any new drug that is introduced to the U.S. market, it is very important to monitor how it is used and if this results in the desired outcomes,” Poeran said in a press release. “Our study results do not support routine use of IV acetaminophen.” - Jashvant Poeran, MD, PhD, Assistant Professor, Population Health Science and Policy, Medicine, Orthopedics, Icahn School of Medicine at Mount Sinai Learn more: https://www.healio.com/gastroenterology/intestinal-disorders/news/online/%7Ba40f0b79- a115-4999-86fa-9e751c3dc8e1%7D/iv-acetaminophen-shows-limited-benefits-after-colorectal-surgery
Web MD – June 18 Today's Sleepy Teens Tomorrow's Heart Patients? — Dennis Thompson Most kids don't get enough sleep, and that may put them on a path to future heart trouble, a new study finds. Young teens who slept less than seven hours a night tended to have more body fat, elevated blood pressure and less healthy cholesterol levels -- all bad for the heart, researchers say. "I was really struck by how little these adolescents are sleeping," said Andrew Varga, MD, PhD, assistant professor of medicine, pulmonary, critical care and sleep medicine at the Icahn School of Medicine at Mount Sinai. "It's not totally surprising, given what I know about kids and their habits, but you would think there would be some drive for these kids to sleep more because they have a high sleep need." - Andrew W. Varga, MD, PhD, Assistant Professor, Medicine, Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.webmd.com/sleep-disorders/news/20180618/todays-sleepy-teens-tomorrows- heart-patients
MD Alert – June 19 Perioperative RBC Transfusions Tied To Higher Risk Of Blood Clots — Marilynn Larkin Perioperative red blood cell (RBC) transfusions may increase patients' risk of new or progressive venous thromboembolism (VTE), researchers say. Ageliki Vouyouka, MD, associate professor of surgery and radiology at the Icahn School of Medicine at Mount told Reuters Health the study "contributes to the medical information that urges practice changes regarding blood transfusion in sick patients. However, we have to keep in mind that this is a nonrandomized trial, very dependent on the correct recording of data by each hospital's personnel, with all the inherent limitations of such a study. There might be other factors not identifiable in the NSQIP dataset that are associated with the different incidence of DVT in the transfused and not transfused group, including length of operation, vascular injury during surgery, hemodynamic changes, and amount of blood loss, all of which are associated with higher rates of transfusion but also higher rates of DVT perioperatively. In addition," Dr. Vouyouka said, "the study analyses the role of transfusion of stored blood cells on perioperative DVT/PE but not the impact of other types of transfusion, such as cell saver, etc. For all these reasons, despite the significance of this study, further investigation utilizing randomized control studies will be necessary to support this very interesting finding," she concluded. - Ageliki G Vouyouka, MD, Associate Professor, Surgery and Radiology, Icahn School of Medicine at Mount Sinai Learn more: http://www.mdalert.com/news/article/perioperative-rbc-transfusions-tied-to-higher-risk-of- blood-clots
Diabetes In Control –June 19 Jeffrey Mechanick Part 1, Introduction Trans-Cultural Endocrinology In part 1 of this exclusive interview, Jeffrey Mechanick, MD,clinical professor of medicine, endocrinology, diabetes and bone disease and director of metabolic support at the Icahn School of Medicine at Mount Sinai talks with Diabetes in Control Publisher Steve Freed during the AACE 2018 convention in Boston, MA about the concept of trans-cultural endocrinology and why it is essential to understand how differences in culture can impact diabetes care. - Jeffrey Mechanick, MD, Clinical Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Director, Metabolic Support, Icahn School of Medicine at Mount Sinai, Medical Director, The Marie-Josee and Henry R. Kravis Center for Cardiovascular Health, Mount Sinai Heart Learn more: http://www.diabetesincontrol.com/jeffrey-mechanick-part-1-introduction-trans-cultural- endocrinology/
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200
From: ITNDaily Subject: Mount Sinai In The News - June 20, 2018 Date: Wednesday, June 20, 2018 1:25:33 PM Attachments: ATT00001.txt
In the News June 20, 2018
Politico New York – June 20 Asthma Test — Nick Niedzwiadek and Amanda Eisenberg Mount Sinai researchers have identified a genetic biomarker for mild to moderate asthma, which can be tested for using a nasal brush. The test can also be used to differentiate asthma from other respiratory conditions such as allergic rhinitis, smoking, upper respiratory infection and cystic fibrosis, according to the study published in Scientific Reports. - Supinda Bunyavanich, MD, MPH, Associate Professor, Genetics and Genomic Sciences, Pediatrics, Icahn School of Medicine at Mount Sinai - Gaurav Pandey, PhD, Assistant Professor, Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai Learn more: https://www.politico.com/states/new-york/newsletters/politico-new-york-health- care/2018/06/20/drug-take-back-bill-close-to-passing-077488
Reuters – June 19 Fathers’ Antidepressant Use Doesn’t Worsen Babies’ Health Risks — Jocelyn Wiener Fathers’ use of antidepressant medications around the time mothers become pregnant does not increase babies’ risk of preterm birth, birth defects, autism or intellectual disability, according to a study in the BMJ. Study leader, Sven Sandin, PhD, assistant professor of psychiatry at the Icahn School of Medicine at Mount Sinai, said that while it has generally been assumed that paternal use of antidepressants holds no risk for a developing baby, this previously had not been well-studied. The results were not “a big surprise,” he said, but are nevertheless important, since there has been extensive research into the risk of mothers taking antidepressants, but less attention paid to fathers. “The findings from this study are reassuring for men using antidepressant medication, showing that this does not increase risk of autism, intellectual disability or birth defects for their infants.” - Sven Sandin, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: https://www.reuters.com/article/us-health-pregnancy-fathers-depression/fathers- antidepressant-use-doesnt-worsen-babies-health-risks-idUSKBN1JF34L Additional coverage: WSAU Radio http://wsau.com/news/articles/2018/jun/19/fathers-antidepressant-use-doesnt-worsen- babies-health-risks/
Huffington Post – June 18 Black Women Face More Trauma During Childbirth— Catherine Pearson According to the most recent CDC data, white women in America experience just under 13 deaths per every 100,000 live births; for black women, it’s more like 44 deaths per 100,000. And the United States is an outlier among other wealthy countries in that our maternal mortality rates continue to trend upward at the same time that every other developed nation in the world has managed to lower theirs. Maternal death has become a full-blown public health crisis that has finally begun to garner mainstream attention. Nationally, just under three-quarters of black women deliver in roughly one- quarter of this country’s hospitals — and those hospitals tend to have much higher rates of severe complications. By contrast, only 18 percent of white women deliver in those hospitals, said Elizabeth Howell, MD, director of the Blavatnik Family Women’s Health Research Institute at the Icahn School of Medicine at Mount Sinai – who led that research. “Part of the disparity that we’re becoming aware of, and hearing more and more about, is because black women are delivering in different hospitals,” she said. “We can actually think about quality improvement in hospitals as an important way to reduce disparities.” - Elizabeth Howell, MD, MPP, Professor, Population Health Science and Policy, Psychiatry, Schizophrenia, Obstetrics, Gynecology and Reproductive Science, Associate Dean, Academic Development, Director, The Blavatnik Family Women’s Health Research Institute, Icahn School of Medicine at Mount Sinai Learn more: https://www.huffingtonpost.com/entry/black-women-childbirth-mortality- trauma_us_5b045eaae4b0784cd2af0f71
News Medical & Life Sciences – June 19 Study Finds IV Acetaminophen To Be No More Effective Than Oral Counterpart For Colectomy Patients Intravenous (IV) acetaminophen is no more effective than oral acetaminophen for patients undergoing colorectal procedures, Mount Sinai researchers report in a first-of-its-kind study. These findings suggest that eliminating use of IV acetaminophen, which is much more expensive than its oral counterpart, may result in very significant cost savings for hospitals with no impact on the patient experience or outcomes. "With any new drug that is introduced to the U.S. market, it is very important to monitor how it is used and if this results in the desired outcomes. Our study results do not support routine use of IV acetaminophen," explained lead investigator Jashvant Poeran, MD, PhD, assistant professor of population health science and policy, medicine and orthopedics at the Icahn School of Medicine at Mount Sinai. "A wide variety of non-opioid adjuvants are available for use, but our knowledge of what works best in whom is still in its infancy," added Andrew Leibowitz, MD, chair of the department of anesthesiology, perioperative, and pain medicine for the Mount Sinai Health System. The study team is currently addressing this same question in other types of surgery, such as hip, knee and shoulder replacement, and anticipates more findings in the near future. - Jashvant Poeran, MD, PhD, Assistant Professor, Population Health Science and Policy, Medicine, Orthopedics, Icahn School of Medicine at Mount Sinai - Andrew B. Leibowitz, MD, Chair, Department of Anesthesiology, Perioperative and Pain Medicine, Mount Sinai Health System, Professor, Anesthesiology, Surgery, Icahn School of Medicine at Mount Sinai Learn more: https://www.news-medical.net/news/20180619/Study-finds-IV-acetaminophen-to-be-no- more-effective-than-oral-counterpart-for-colectomy-patients.aspx Additional coverage: UPI https://www.upi.com/Study-IV-acetaminophen-just-as-effective-as-oral-Tylenol-in-bowel- procedures/1131529422829/
Spectrum News – June 20 Mutations In Autism Gene Trigger Milder Effects Than Doses Its Loss — Bahar Gholipour People with mutations in SHANK3 have intellectual disability and other features of Phelan-McDermid syndrome, the condition most closely associated with this gene. However, these individuals have milder traits than do those missing a chunk of DNA that includes the gene, according to a new study. “It’s clear that other genes in the region contribute to the phenotype, but, at the same time, losing only SHANK3 is enough to cause a pretty significant phenotype,” said lead researcher, Alexander Kolevzon, MD, professor of psychiatry and pediatrics at the Icahn School of Medicine at Mount Sinai, director of child and adolescent psychiatry for the Mount Sinai Health System, and clinical director of the Seaver Autism Center for Research and Treatment at Mount Sinai. “For this study, we grouped all mutations together. But where the mutation occurs in the gene could also have relevance,” said Dr. Kolevzon. - Alexander Kolevzon, MD, Professor, Psychiatry, Pediatrics, Icahn School of Medicine at Mount Sinai, Director, Child and Adolescent Psychiatry, Mount Sinai Health System, Clinical Director, The Seaver Autism Center for Research and Treatment at Mount Sinai Learn more: https://www.spectrumnews.org/news/mutations-autism-gene-trigger-milder-effects-loss/
Lifestyles Magazine – June 19 Crystal Party Mount Sinai Health System threw its 33rd annual Crystal Party, held at the Central Park Conservatory. The event, chaired by trustee Henry Cornell and his wife, Vanessa, raised almost $4 million. More than 1,200 guests, including Mount Sinai staff, supporters, and leaders, enjoyed celebrating the organization’s achievements in research, education, and patient care. The night’s speakers were Jeannie and Jim Gaffigan, co-writers for The Jim Gaffigan Show. They spoke about Jeannie’s battle with a rare brain tumor, which was successfully treated by the hospital’s chair of neurosurgery, Dr. Joshua Bederson, who use the virtual reality technology he pioneered. - Joshua Bederson, MD, Professor, System Chair, Department of Neurosurgery, Mount Sinai Health System, Clinical Director, Neurosurgery Simulation Core Learn more: No web link available.
Lifestyles Magazine – June 19 Spotlight On Doctors Amongst the donors, administrators, thinkers, and lay-leaders, exists a subset of crucial actors: they are by the bedside, in the operating room, teaching in the lecture halls, and conducting vital research in real time. They are the doctors. Of the tens of thousands of physicians changing and saving lives on a minute- to-minute basis, we present three of Mount Sinai Hospital’s finest. Among those featured were Elisa Port, MD, director of the Dubin Breast Center and chief of breast surgery at the Mount Sinai Hospital; Frederick Friedman Jr., associate professor of obstetrics, gynecology and reproductive science at the Icahn School of Medicine at Mount Sinai and director of the division of obstetrics, gynecology and reproductive science at the Mount Sinai Health System. - Elisa Port, MD, FACS, Director of the Dubin Breast Center and Chief of Breast Surgery, The Mount Sinai Hospital - Frederick Friedman Jr., MD, Associate Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Division of Generalists, Department of Obstetrics, Gynecology and Reproductive Science, Mount Sinai Health System Learn more: No web link available.
Lifestyles Magazine – June 19 The President’s Letter – Adina Erem Isenberg Early detection of breast cancer saved Adina Erem Isenberg’s life. She was diagnosed at the age of 40. Some people believe screenings such as a mammogram and ultrasound may increase the chance of developing breast cancer and can lead to false positives, painful biopsies, and unnecessary stress. Adina is not one of those people. For her, her life was saved by a combination of a mammogram and ultrasound. During her chemotherapy, Adina was fortunate her doctors were receptive to using the Cold Cap. It is a technology from Europe, developed in the 1970s, that can prevent hair loss from chemotherapy. Thankfully, between her doctors, nurses, and dedicated cold capper, she was able to hide her cancer from the world. Adina feels it’s critical to be an advocate for yourself and have a doctor who can help us understand how these guidelines specifically apply to each one of us. - Elisa Port, MD, FACS, Director of the Dubin Breast Center and Chief of Breast Surgery, The Mount Sinai Hospital - Frederick Friedman Jr., MD, Associate Professor, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, Director, Division of Generalists, Department of Obstetrics, Gynecology and Reproductive Science, Mount Sinai Health System Learn more: No web link available.
Our Town NY – June 13 Prescribing Literacy — Angela Barbuti As a pediatrician in the Division of General Pediatrics at The Mount Sinai Hospital, Leora Mogilner, MD, brought Reach Out and Read, a national literacy nonprofit, there in 1998. When children come in for a pediatric visit, starting as newborns, they a given a brand new developmentally and culturally appropriate book to take home. Dr. Mogilner also serves as the medical director of Reach Out and Read of Greater New York, which recently marked 20 years of serving the city’s most underserved communities with the tools of literacy. On June 5, at the Leob Boathouse in Central Park, she was honored for her work with the program, which includes helping the organization grow from serving only 18 sites in 2000 to now 275,000 kids yearly at 223 sites. “We would ultimately like to ensure that we have funding so that every child who goes to the doctor for a well visit is able to leave with a brand new book they’re excited about. And parents get information they need to make reading and sharing books a part of their children’s lives,” Dr. Mogilner said. - Leora Mogilner, MD, Associate Professor, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: http://www.ourtownny.com/local-news/20180613/prescribing-literacy
MedPage Today – June 19 No Link Between Lithium in Pregnancy, Adverse Delivery Outcomes — Molly Walker There was no link between lithium use in pregnancy and certain pregnancy complications or adverse delivery outcomes, though there was a higher risk of hospital readmission and congenital malformations, a meta-analysis found. "Given the well-documented effectiveness of lithium in reducing relapse in the perinatal period, some important clinical considerations are either to continue lithium in a lower dose during the first trimester or to restart lithium after the first trimester or immediately postpartum,” said co-author, Veerle Bergink, MD, PhD, senior faculty in psychiatry, obstetrics, gynecology and reproductive science at the Icahn School of Medicine at Mount Sinai. However, there was no increased risk of major cardiac malformations in the lithium-exposed group compared with the reference group, the authors said. - Veerle Bergink, MD, PhD, Senior Faculty, Psychiatry, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: https://www.medpagetoday.com/obgyn/pregnancy/73585 Additional coverage: Newsmax Health https://www.newsmax.com/thewire/lithium-birth-defects-study- bipolar/2018/06/19/id/867132/ MindBodyGreen https://www.mindbodygreen.com/articles/june-20-2018-wellness-news
Advanced Science News – June 20 Advanced Protocol For Modeling Retinal Pigment Epithelium-Related Diseases — Nidhi Bansal Impact of a retinal degenerative disease like macular degeneration and retinitis pigmentosa is debilitating due to partial or complete vision loss. The underlying reason is damage (age-related, genetic or environmental) to a thin layer of cells, the retinal pigment epithelium (RPE), located between the photoreceptor of the neural retina and the choroidal blood supply at the back of the eye. In an era where stem cell technology holds promise for robust disease-modeling and improved targeted cell-based therapies, effective treatment for a retinal degenerative disease is an unmet clinical need. Addressing this problem, Marie Fernandes, senior associate researcher of cell, developmental and regenerative biology at the Icahn School of Medicine at Mount Sinai, and coworkers in the Blenkinsop Laboratory, have developed a technique to create a human “RPE disease in a dish model.” In a recently published article in Current Protocols in Stem Cell Biology, they elaborate highly efficient and reproducible protocols for isolation and culture of adult human RPE stem cell-derived cells. - Marie Fernandes, Senior Associate Researcher, Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai Learn more: https://www.advancedsciencenews.com/advanced-protocol-for-modeling-retinal-pigment- epithelium-related-diseases/
Wink News – June 18 Triton Tracks Blood Loss At Birth In the United States, 700 women die every year from labor and delivery complications. The leading cause of maternal death is excessive, unexpected bleeding. But now a high-tech system can alert doctors and nurses in real time if a woman is in danger. Three percent of all women experience a dangerous hemorrhage during or after labor and delivery. Daniel Katz, MD, assistant professor of anesthesiology, perioperative and pain medicine at the Icahn School of Medicine at Mount Sinai said, “The traditional way of monitoring blood loss is done by visual inspection. Meaning we essentially look at the saturated pads and the operative field and make an estimate with our best guess what the blood loss it.” Now a cutting-edge system called the Triton is taking the guess work out by using an app to analyze the amount of blood on surgical sponges and equipment. Doctors or nurses calibrate the system using a barcode. Then they hold up sponges and pads in front of the computer or iPad camera. Dr. Katz says for anything that can’t be scanned by the app, they use a Bluetooth-enabled smart scale. If a doctor types in the surgical tools that are being weighed, the computer can calculate blood loss that way. - Daniel Katz, MD, Assistant Professor, Anesthesiology, Perioperative and Pain Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.winknews.com/2018/06/18/triton-tracks-blood-loss-at-birth/
Diabetes In Control – June 19 Jeffrey Mechanick, MD: AACE 2018 Full Interview — Joy Pape In an exclusive interview during the AACE 2018 convention, Jeffrey Mechanick, MD, clinical professor of medicine, endocrinology, diabetes and bone disease at the Icahn School of Medicine at Mount Sinai, talks about transcultural endocrinology and gives a summary of the recent activities for a program focused on diabetes care across America. “The word ‘transcultural’ you could argue is a little bit of a made-up word but what it really describes is the process of taking evidence-based recommendations for a very specific medical problem, in this case, diabetes care, from a source population, a source culture with a certain distribution of races and ethnicities, and then, making it portable for a target population with perhaps a different culture, and within that culture, a different distribution of ethnicities and races,” said Dr. Mechanick. - Jeffrey Mechanick, MD, Clinical Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Director, Metabolic Support, Icahn School of Medicine at Mount Sinai, Medical Director, The Marie- Josee and Henry R. Kravis Center for Cardiovascular Health, Mount Sinai Heart Learn more: http://www.diabetesincontrol.com/jeffrey-mechanick-full-interview/
Medscape – June 19 New Treatment Guidelines And A New Biomarker In MS — Stephen Krieger, MD Stephen Krieger, MD, associate professor of neurology at the Icahn School of Medicine at Mount Sinai and a neurologist at the Corinne Goldsmith Dickinson Center for Multiple Sclerosis at the Mount Sinai Hospital, reports on two updates in multiple sclerosis (MS) that were presented at the 2018 American Academy of Neurology meeting in April. One of the updates from the meeting relates to how we currently practice MS care, and the other – a little more forward-looking – is about how this care may change in the near future. “The 2018 MS guideline recommendations are a great resource for the care of patients with MS. I also think we could cite these recommendations when helping our patients obtain third-party payer authorizations based on our treatment decisions,” said Dr. Krieger. - Stephen Krieger, MD, Associate Professor, Neurology, Icahn School of Medicine at Mount Sinai, Neurologist, The Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Mount Sinai Hospital Learn more: https://www.medscape.com/viewarticle/897963
Health Magazine – June 18 The Breast Cancer Pre-Screening Test You Should Get By Age 30 — Sarah Klein An article published in the Journal of the American College of Radiology addressing breast cancer screening recommendations for high-risk women has one idea: Let’s get all women evaluated for breast cancer risk by age 30. Not every PCP or ob-gyn will be well-versed in breast cancer risk, however. Yours may decide to refer you to a colleague or a breast clinic instead. It’s that lack of expertise among some doctors that concerns Charles L. Shapiro, MD, director of cancer survivorship and translational breast cancer research at the Tisch Cancer Institute and professor of medicine at the Icahn School of Medicine at Mount Sinai. “I think that the idea of the risk assessment at earlier ages is a good one. It’s an extension of people taking control of their own health and finding out what their risk is. But the practicality of it and logistics are not set up to do it at the current time. I’m not so sure the infrastructure’s in place.” - Charles L. Shapiro, MD, Director, Cancer Survivorship, Translational Breast Cancer Research, The Tisch Cancer Institute, Professor, Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.health.com/condition/breast-cancer/breast-cancer-risk-assessment
Healio: Psychiatrics Annals – June 18 Suicide Rates Increasing Across The U.S. — Savannah Demko Suicide rates rose significantly in 44 states, with 25 states experiencing increases of more than 30 percent, between 1999 and 2016 in the United States, CDC data revealed. “Although the authors discuss multiple suicide-related factors, its analysis of the National Vital Statistics System coded death certificate records has identified two notable new directions for the prevention efforts,” said Igor Galynker, MD, professor of psychiatry at the Icahn School of Medicine at Mount Sinai and associate chairman of psychiatry research at Mount Sinai Beth Israel. “Over the last 10 years, we obtained encouraging results defining suicide-specific mental syndromes and creating new methods of suicide risk assessment not reliant on self-disclosed suicidal ideation and intent. The data analyses reported by the CDC lend new support to this approach.” - Igor Galynker, MD, Professor, Psychiatry, Icahn School of Medicine at Mount Sinai, Associate Chairman, Psychiatry Research, Mount Sinai Beth Israel Learn more: https://www.healio.com/psychiatry/suicide/news/online/%7B1c22d47e-e6cd-4263-bbcc- 1202c3ac073a%7D/suicide-rates-increasing-across-the-us
Insider – June 19 15 Myths About Sunburn You Should Stop Believing — Arielle Tschinkel The American Academy of Dermatology estimates that one in five Americans will develop skin cancer in their lifetime, with approximately 9,500 people in the U.S. receiving a skin cancer diagnosis every single day. Even one bad sunburn during your childhood or teen years can increase your risk of developing melanoma, the most common skin cancer, as an adult. According to Joshua Zeichner, MD, assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai and director of cosmetic and clinical research in dermatology at The Mount Sinai Hospital, “a product with an SPF 30 means that you get the same amount of sun exposure after 30 minutes outside as you would get if you were unprotected outdoors for one minute.” The truth is that no sunscreen is 100% effective in blocking the sun's rays, which is why sunscreen is no longer referred to as sunblock. But a higher SPF has been shown to better protect skin, according to findings recently published in the Journal of the American Academy of Dermatology. - Joshua Zeichner, MD, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research in Dermatology, The Mount Sinai Hospital Learn more: http://www.thisisinsider.com/sunburn-facts-tips-and-healing-myths-2018-6
Women’s Health – June 19 Does Milk Cause Acne? — Korin Miller Skim milk has been linked with acne breakouts in people who are already predisposed to them, said Joshua Zeichner, MD, assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai and director of cosmetic and clinical research in dermatology at the Mount Sinai Hospital. It's hard to say whether it's due to inflammation caused by the sugars in milk or whether hormones passed on from the nursing cow are to blame, he says. For starters, using sunscreen is incredibly important for lowering your risk of developing skin cancer. Whether it will make you break out or not really depends on the product and your skin, said Gary Goldenberg, MD, assistant professor of dermatology and pathology at the Icahn School of Medicine at Mount Sinai and director of the dermatology faculty practice at Tthe Mount Sinai Hospital. “Not every brand is right for everyone's skin,” Dr. Goldenberg says. He recommends looking for the words "non-comedogenic" on your bottle—which basically means that it won't block your pores. “I counsel patients to try several brands to find the one that works best for them,” Dr. Goldenberg says. - Joshua Zeichner, MD, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research in Dermatology, The Mount Sinai Hospital - Gary Goldenberg, MD, Assistant Professor, Dermatology, Pathology, Icahn School of Medicine at Mount Sinai, Director, Dermatology Faculty Practice, The Mount Sinai Hospital Learn more: https://www.womenshealthmag.com/beauty/a21527079/acne-causes-quiz/
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 21, 2018 Date: Thursday, June 21, 2018 12:35:48 PM Attachments: ATT00001.txt
In the News June 21, 2018
International Business Times – June 21 Mount Sinai Health System Launches ‘Road To Resilience’ Podcast Mount Sinai Health System has created a new monthly podcast series, Road to Resilience, which debuts on June 27. The series is based on the well-received book Resilience: The Science of Mastering Life’s Greatest Challenges, co-authored by Dennis S. Charney, MD, Anne and Joel Ehrenkranz Dean of the Icahn School of Medicine at Mount Sinai, and Steven Southwick, MD, Professor of Psychiatry at Yale University. The podcast features thought-provoking insight from renowned experts as they explain the science behind resilience. The inaugural episode highlights Dr. Charney, who shares his journey of survival and a highly publicized recovery after being ambushed by a gunman who intentionally targeted him. “Once you’re a trauma victim you’re always a trauma victim, but part of the recovery is to make sense of that and grow. It takes time, but you can do it and have a positive outcome,” said Dr. Charney. - Dennis S. Charney, MD, Anne and Joel Ehrenkranz Dean, Icahn School of Medicine at Mount Sinai, and President for Academic Affairs, Mount Sinai Health System Learn more: http://markets.financialcontent.com/ibtimes/news/read/36499923 Additional coverage: Pittsburgh Post-Gazette http://markets.post-gazette.com/postgazette/news/read/36499923 News Channel 10 http://www.newschannel10.com/story/38474808/mount-sinai-health-system-launches-%E2%80%98road-to-resilience%E2%80%99-podcast Star Tribune http://markets.financialcontent.com/startribune/news/read/36499923/Mount_Sinai_Health_System_Launches_%C3%A2%E2%82%AC%CB%9CRoad_To_Resilience%C3%A2%E2%82%AC%E2%84%A2_Podcast? user_ref= The Buffalo News http://markets.buffalonews.com/buffnews/news/read/36499923/Mount_Sinai_Health_System_Launches_%C3%A2%E2%82%AC%CB%9CRoad_To_Resilience%C3%A2%E2%82%AC%E2%84%A2_Podcast Street Insider http://markets.financialcontent.com/streetinsider/news/read/36499923 Benzinga https://www.benzinga.com/pressreleases/18/06/p11912800/mount-sinai-health-system-launches-road-to-resilience-podcast
The New York Times – June 21 A Common Virus May Play Role In Alzheimer’s Disease, Study Finds — Pam Belluck It has long been a controversial theory about Alzheimer’s disease, often dismissed by experts as a sketchy cul-de-sac off the beaten path from mainstream research. But a new study by a team that includes prominent Alzheimer’s scientists who were previously skeptics of this theory may well change that. The research offers compelling evidence for the idea that viruses might be involved in Alzheimer’s, particularly two types of herpes that infect most people as infants and then lie dormant for years. “These viruses are probably significant players in driving the immune system in Alzheimer’s,” said Joel Dudley, PhD, the study’s senior author and the director of the Next Generation Healthcare Institute at the Icahn School of Medicine at Mount Sinai. “I think they’re like gas on the flames of some pathology that may be immune-driven.” - Joel Dudley, PhD, Director, Next Generation Healthcare Institute, Associate Professor, Genetics and Genomic Sciences, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Executive Vice President, Precision Health, Mount Sinai Health System - Samuel Gandy, MD, PhD, Professor, Neurology, Psychiatry, Associate Director, Alzheimer’s Disease Research Center, Icahn School of Medicine at Mount Sinai, Director, The Mount Sinai Center for Cognitive Health and NFL Neurological Care Learn more: https://www.nytimes.com/2018/06/21/health/alzheimers-virus-herpes.html Additional coverage: Scientific American https://www.scientificamerican.com/article/harder-evidence-builds-that-viruses-play-a-role-in-alzheimers/ STAT News https://www.statnews.com/2018/06/21/herpes-viruses-alzheimers-disease-role/ The Washington Times https://www.washingtontimes.com/news/2018/jun/21/alzheimers-breakthrough-links-viral-herpes-to-brai/ NPR https://www.npr.org/sections/health-shots/2018/06/21/621908340/researchers-find-herpes-viruses-in-brains-marked-by-alzheimers-disease Associated Press http://www.dailyherald.com/article/20180621/news/306219946/ NBC News https://www.nbcnews.com/health/health-care/childhood-virus-hhv-linked-alzheimer-s-decades-later-n885181 The Telegraph https://www.telegraph.co.uk/science/2018/06/21/alzheimers-disease-may-triggered-herpes-virus-scientists-suspect/ Healio: Psychiatric Annals https://www.healio.com/psychiatry/alzheimers-disease-dementia/news/online/%7B8dee2b36-6fbc-4d04-8754-e8923242e417%7D/viral-activity-may-play-role-in-alzheimers-disease Genetic Engineering & Biotechnology News https://www.genengnews.com/gen-news-highlights/could-alzheimers-be-triggered-by-herpes-virus/81255942 Sci-News http://www.sci-news.com/medicine/herpesvirus-brains-alzheimers-disease-patients-06122.html WPSU http://radio.wpsu.org/post/researchers-find-herpes-viruses-brains-marked-alzheimers-disease
Politico New York – June 21 Just As Good — Amanda Eisenberg & Nick Niedzwiadek IV acetaminophen is no more effective than oral acetaminophen for patients undergoing colorectal procedures, according to a new study from Mount Sinai researchers. - Jashvant Poeran, MD, PhD, Assistant Professor, Population Health Science and Policy, Medicine, Orthopedics, Icahn School of Medicine at Mount Sinai - Andrew B. Leibowitz, MD, Chair, Department of Anesthesiology, Perioperative and Pain Medicine, Mount Sinai Health System, Professor, Anesthesiology, Surgery, Icahn School of Medicine at Mount Sinai Learn more: https://www.politico.com/states/new-york/newsletters/politico-new-york-health-care/2018/06/21/city-council-grills-h-h-on-behavioral-health-treatment-078039 Additional coverage: Becker’s Hospital Review https://www.beckershospitalreview.com/opioids/iv-tylenol-no-longer-seen-as-the-solution-to-ending-the-opioid-epidemic.html JD News http://www.jdnews.com/news/20180620/your-health-growing-case-against-iv-tylenol-once-seen-as-solution-to-opioid-crisis Watertown Daily Times http://www.watertowndailytimes.com/national/iv-pain-drugs-new-studies-show-they-offer-little-benefit-over-pill-form-20180620 Infosurhoy http://www.infosurhoy.com/cocoon/saii/xhtml/en_GB/health/study-iv-acetaminophen-just-as-effective-as-oral-tylenol-in-bowel-procedures/
Crain’s Health Pulse – June 21 Who’s News Erik Lium is now executive vice president of Mount Sinai Innovation Partners, overseeing management, licensing, and commercialization of technologies at the health system and the Icahn School of Medicine at Mount Sinai. He will also manage the i3 Asset Accelerator. Lium was previously senior vice president of MSIP. http://www.crainsnewyork.com/article/20180621/PULSE/180629986/city-council-members-criticize-nonpublic-hospitals-at-hearing-on
Psych Congress Network – June 20 Paternal Periconception Antidepressant Use Doesn’t Worsen Outcomes — Jocelyn Wiener Fathers' use of antidepressant medications around the time mothers become pregnant does not increase babies' risk of preterm birth, birth defects, autism or intellectual disability, according to a study in the BMJ. Study leader Sven Sandin, PhD, assistant professor of psychiatry at the Icahn School of Medicine at Mount Sinai said, that while it has generally been assumed that paternal use of antidepressants holds no risk for a developing baby, this previously had not been well-studied. The results were not "a big surprise," he said, but are nevertheless important, since there has been extensive research into the risks of mothers taking antidepressants, but less attention paid to fathers. "The findings from this study are reassuring for men using antidepressant medication, showing that this does not increase risk of autism, intellectual disability or birth defects for their infants." - Sven Sandin, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: https://www.psychcongress.com/news/paternal-periconception-antidepressant-use-doesnt-worsen-outcomes
Orthopedics This Week – June 21 A New Data On Impact Of Spine Tumor Location — Elizabeth Hofheinz, MPH, MEd A retrospective cohort study has found that when it comes to spine tumors, the location is critical. Co-author, Samuel K. Cho, MD, associate professor of orthopedics and neurosurgery at the Icahn School of Medicine at Mount and chief of spine surgery at Mount Sinai West said, “Spine is one of the most common organs for bony metastasis. We as spine surgeons take care of tumor patients, but we as individual spine surgeons, unless you work at a tertiary cancer center, do not take care of enough tumor patients to have adequate data for meaningful research.” The authors wrote, “The purpose of this study was to assess the impact of tumor location in the cervical, thoracic, or lumbosacral spine on 30-day perioperative mortality and morbidity after surgical decompression of metastatic extradural spinal tumors.” - Samuel K. Cho, MD, Associate Professor, Orthopedics, Neurosurgery, Icahn School of Medicine at Mount Sinai, Chief, Spine Surgery, Mount Sinai West Learn more: https://ryortho.com/breaking/new-data-on-impact-of-spine-tumor-location/
Medscape – June 21 Reduced-Intensity Warfarin Safe With On-X Heart Valve — Sue Hughes Low-dose warfarin plus aspirin was associated with significantly less bleeding without significantly increasing thromboembolic events compared with standard-dose warfarin in patients who underwent aortic valve replacement with the On-X (On-X Life Technologies) mechanical valve in the PROACT study. "This trial has been more than 10 years in the making," said lead author, John D. Puskas, MD, site chair of cardiovascular surgery at Mount Sinai St. Luke’s and Mount Sinai West, professor of cardiovascular surgery at the Icahn School of Medicine at Mount Sinai. "The goal was to explore if this particular mechanical valve can be used safely with reduced doses of anticoagulation, and results show that yes, it can." He concluded, “Our results show that dual antiplatelet therapy is not appropriate for patients with mechanical heart valves.” - John D. Puskas, MD, Site Chair, Cardiovascular Surgery, Mount Sinai St. Luke’s, Mount Sinai West, Mount Sinai Beth Israel, Professor, Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai Learn more: https://www.medscape.com/viewarticle/898381
Our Town NY – June 21 Making Patients Comfortable – Michele Willens You could hardly call it a trend, but palliative care is a rapidly growing field in the medical world today. While many confuse it with hospice, it is not the same thing. Just spend a few hours at the Wiener Family Palliative Care Unit, on the sixth floor of the Klingenstein Pavilion at Mount Sinai, and you will not feel despair, but rather gratitude and hope. Considered by many the national model, the unit is not about the end of life, most associated with hospice. R. Sean Morrison, MD, professor and chair of the department of geriatrics and palliative medicine at the Icahn School of Medicine at Mount Sinai, and his colleagues conducted a study with Trinity College that was published in JAMA Internal Medicine showing that when palliative care is provided alongside “curative treatments,” patients feel better, their quality of life improves, and costs go down. - R. Sean Morrison, MD, Professor, Chair, Ellen and Howard C. Katz, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai - Evan L. Zanzula, Chaplain, Geriatrics and Palliative Medicine, The Mount Sinai Hospital Learn more: http://www.ourtownny.com/local-news/20180621/making-patients-comfortable/1
Pittsburgh Post-Gazette – June 21 MBI Group Completes 4,000 SF Urgent Care Center For Mount Sinai Doctors MBI Group, a New York City-based construction and general contracting firm, announced the successful completion of a 4,000 square-foot build-out for Mount Sinai Doctors Urgent Care Center, a walk-in medical facility, located at 516-518 East 20th Street in Manhattan’s Stuyvesant Town-Peter Cooper Village. Mount Sinai Doctors Urgent Care Center offers walk-in patients primary care and pediatric services, staffed by a team of family medicine internists and pediatricians featuring state-of-the-art exam rooms and imaging services. - Mount Sinai Doctors Urgent Care Center Learn more: http://markets.post-gazette.com/postgazette/news/read/36501216/mbi_group_completes_4 Additional coverage: WALB News http://www.walb.com/story/38476187/mbi-group-completes-4000-sf-urgent-care-center-for-mount-sinai-doctors
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 22, 2018 Date: Friday, June 22, 2018 12:13:51 PM Attachments: ATT00001.txt
In the News June 22, 2018
Metro – June 22 Mount Sinai Celebrates 50 Years Of Supporting LGBTQ And Other City Youth — Nikki M. Mascali The Mount Sinai Adolescent Health Center has long supported LGBTQ and other city youth and is celebrating a golden anniversary of its own this year. “We are New York City’s largest provider of high- quality, comprehensive, free health and wellness services for youth ages 10 through 24, ranging from primary care and mental health for all young people to special programs for transgender youth, teen parents and more,” said Angela Diaz, MD, professor of adolescent health, pediatrics and preventive medicine at the Icahn School of Medicine at Mount Sinai and director of the Mount Sinai Adolescent Health Center. More than 90 percent of MSAHC’s patients are people of color, and 70 percent do not have health insurance – including transgenders, who face large inequities in health care, especially those under 18, added Dr. Diaz. “Many of our transgender young people say the center saved their lives,” Dr. Diaz said. “We accept them as their true selves, provide a safe, gender-affirming space and help them and their families along their journey.” - Angela Diaz, MD, Jean C. & James W. Crystal Professor, Adolescent Health, Professor, Pediatrics, Preventive Medicine, Icahn School of Medicine at Mount Sinai, Director, Mount Sinai Adolescent Health Center Learn more: https://www.metro.us/news/local-news/new-york/mount-sinai-celebrates-50-years- supporting-nyc-youth
The Guardian – June 21 Alzheimer’s Link To Herpes Virus In Brain, Say Scientists— Hannah Devlin The presence of viruses in the brain has been linked to Alzheimer’s disease in research that challenges conventional theories about the onset of dementia. The results, based on tests of brain tissue from nearly 1,000 people, found that two strains of herpes virus were far more abundant in the brains of those with early-stage Alzheimer’s than in healthy controls. However, scientists are divided on whether viruses are likely to be an active trigger, or whether the brains of people already on the path towards Alzheimer’s are simply more vulnerable to infection. “The viral genomes were detectable in about 30 percent of Alzheimer’s brains and virtually undetectable in the control group,” said Samuel Gandy, MD, PhD, professor of neurology and psychiatry, director of the Alzheimer’s Disease Research Center at the Icahn School of Medicine at Mount Sinai. “While these findings do potentially open the door for new treatment options to explore in a disease where we’ve had hundreds of failed trials, they don’t change anything that we know about the risk and susceptibility of Alzheimer’s disease or our ability to treat it today,” said Dr. Gandy. - Joel Dudley, PhD, Director, Next Generation Healthcare Institute, Associate Professor, Genetics and Genomic Sciences, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Executive Vice President, Precision Health, Mount Sinai Health System - Samuel Gandy, MD, PhD, Professor, Neurology, Psychiatry, Associate Director, Alzheimer’s Disease Research Center, Icahn School of Medicine at Mount Sinai, Director, The Mount Sinai Center for Cognitive Health and NFL Neurological Care - Benjamin P. Readhead, Icahn Institute for Multiscale Biology, Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai Learn more: https://www.theguardian.com/society/2018/jun/21/alzheimers-link-to-herpes-virus-in-brain- say-scientists Additional coverage: Daily Mail http://www.dailymail.co.uk/health/article-5870075/Herpes-strains-90-percent-abundant- brains-sufferers-study-finds.html Alz Forum https://www.alzforum.org/news/research-news/aberrant-networks-alzheimers-tied-herpes- viruses News 12 Long Island http://longisland.news12.com/clip/14438487/new-study-finds-possible-trigger-for- alzheimers Axios https://www.axios.com/newsletters/axios-science-9a20240d-b7bb-44e7-9e71-9562d4009a5b.html Research Gate https://www.researchgate.net/blog/post/new-evidence-for-viruses-role-in-alzheimers Science Daily https://www.sciencedaily.com/releases/2018/06/180621121914.htm Medical News Today https://www.medicalnewstoday.com/articles/322223.php WKRN News https://www.wkrn.com/news/health-news/new-evidence-that-viruses-may-play-a-role-in- alzheimer-s/1253588861 New Atlas https://newatlas.com/herpes-virus-alzheimers-disease/55137/ ABC News https://abcnews.go.com/Health/wireStory/evidence-viruses-play-role-alzheimers-56058419 NPR https://www.npr.org/sections/health-shots/2018/06/21/621908340/researchers-find-herpes-viruses-in- brains-marked-by-alzheimers-disease Medscape https://www.medscape.com/viewarticle/898434 Science News https://www.sciencenews.org/article/alzheimers-herpesvirus-possible-link Infection Control Today https://www.infectioncontroltoday.com/viral/unusually-high-levels- herpesviruses-found-alzheimer-s-disease-brain Business Insider http://www.businessinsider.com/herpes-may-play-a-role-in-developing-alzheimers- disease-2018-6 WebMD https://www.webmd.com/alzheimers/news/20180621/could-herpes-virus-play-a-role-in- alzheimers OZY https://www.ozy.com/presidential-daily-brief/pdb-87556 NBC New York https://www.nbcnewyork.com/news/local/Migrant-Children-Reunited-Melania-Trump- Jacket-Antwon-Rose-Jr-Herpes-Viruses-Alzheimers-Gaming-Disorder-Addiction-Roseanne-Spinoff- Charles-Krauthammer-Dies-486221911.html
Politico New York – June 22 IV Acetaminophen— Amanda Eisenberg and Nick Niedzwiadek Intravenous versions of medicines like Tylenol have gained in usage as an alternative to powerful painkillers that fueled the opioid crisis. However it’s staggeringly more expensive than typical acetaminophen — roughly $40 for a 1,000-milligram dose, versus a fraction of $1 for the pill equivalent — and recent studies have show little to no increase in effectiveness. Read more here. - Jashvant Poeran, MD, PhD, Assistant Professor, Population Health Science and Policy, Medicine, Orthopedics, Icahn School of Medicine at Mount Sinai - Andrew B. Leibowitz, MD, Chair, Department of Anesthesiology, Perioperative and Pain Medicine, Mount Sinai Health System, Professor, Anesthesiology, Surgery, Icahn School of Medicine at Mount Sinai Learn more: https://www.politico.com/states/new-york/newsletters/politico-new-york-health- care/2018/06/22/short-term-health-insurance-plans-still-prohibited-078422 Additional coverage: The Fix https://www.thefix.com/can-iv-tylenol-help-curb-opioid-crisis
NY1 News – June 13 New Device Offers Relief Beyond Traditional Nasal Spray — Erin Billups Warm weather, bright skies, and blooming foliage can list the worst of moods, or, make you sneeze. Nikki Nolan has been battling allergies, or chronic rhinitis, for more than ten years now. Finding little relief through over-the-counter remedies, she adapted to the discomfort. However, her symptoms began to worsen as she dedicated more time to running. Unable to handle the worsening, she sought help. Finding only moderate relief from nasal sprays and allergy pills, Nolan decided to undergo a new procedure, Clarafix, suggested by her rhinologist, Anthony Del Signore, MD, assistant professor of otolaryngology at the Icahn School of Medicine at Mount Sinai and director of rhinology and endoscopic skull base surgery at Mount Sinai Union Square, which uses cryotherapy to freeze irritated nerves. "So we produce an injury to the nerve. There we're thinking that it's more of a nerve issue that's over sensitized and so we're hitting the reset button to allow for the nerve to sort of calm down for a period of time," said Dr. Del Signore. The procedure takes just minutes, and can be done in the doctor’s office. - Anthony Del Signore, MD, Assistant Professor, Otolaryngology, Icahn School of Medicine at Mount Sinai, Director, Rhinology and Endoscopic Skull Base Surgery, Mount Sinai Union Square Learn more: http://www.ny1.com/nyc/all-boroughs/health-and-medicine/2018/06/21/a-new-device-offers- relief-beyond-traditional-nasal-spray#
Le Quotidien Du Medecin – June 6 No Link Between Lithium in Pregnancy, Adverse Delivery Outcomes — Fabienne Rigal There was no link between lithium use in pregnancy and certain pregnancy complications or adverse delivery outcomes, though there was a higher risk of hospital readmission and congenital malformations, a meta-analysis found. "Given the well-documented effectiveness of lithium in reducing relapse in the perinatal period, some important clinical considerations are either to continue lithium in a lower dose during the first trimester or to restart lithium after the first trimester or immediately postpartum,” said co-author, Veerle Bergink, MD, PhD, senior faculty in psychiatry, obstetrics, gynecology and reproductive science at the Icahn School of Medicine at Mount Sinai. However, there was no increased risk of major cardiac malformations in the lithium-exposed group compared with the reference group, the authors said. - Veerle Bergink, MD, PhD, Senior Faculty, Psychiatry, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: https://www.lequotidiendumedecin.fr/actualites/article/2018/06/19/lithium-pendant-la- grossesse-des-malformations-foetales-mais-moins-quon-pensait-et-pas-cardiaques_858999
Cure Today – June 22 Expert Talks Immunotherapy, Unanswered Questions In Metastatic Bladder Cancer — Brielle Urciuoli The treatment landscape of patients with metastatic bladder cancer may be drastically changing in the future, as two large trials are investigating the use of immunotherapy in the second-line setting for these patients. Matthew Galsky, MD, director of the Novel Therapeutics Program, Clinical Trials Program and Genitourinary Medical Oncology at the Tisch Cancer Institute, and professor of urology, medicine, hematology and medical oncology at the Icahn School of Medicine at Mount Sinai, discussed these trials and how the role of chemotherapy may change down the line. “I see a potential scenario where chemotherapy plays a lesser role in the treatment of bladder cancer, but I don't suspect it's going away. I suspect in at least some patients the combination of chemotherapy and immune checkpoint blockade, if the clinical trials read out how we think they might read out. That will be standard of care at least for some patients,” said Dr. Galsky. “I think the question of whether or not chemotherapy alone will have any role in the treatment of bladder cancer in the future is a very interesting question. I think it's possible that it won’t.” - Matthew Galsky, MD, Director, The Novel Therapeutics Program, Clinical Trials Program, Genitourinary Medical Oncology, The Tisch Cancer Institute at Mount Sinai, Professor, Urology, Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai Learn more: https://www.curetoday.com/articles/expert-talks-immunotherapy-unanswered-questions-in- metastatic-bladder-cancer
Cure Today – June 21 Insurance Disparities Among Medicaid Patients With NSCLC Leads To Worse Survival — Kristie L. Kahl Despite the Affordable Care Act (ACA) and Medicaid expansion in 2010, insurance disparities among cause-specific mortalities in individuals with non-small cell lung cancer (NSCLC) still exist, according to study results presented at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting. “The most important thing here is to find the Medicaid population actually having the worst outcome of lung cancer survivors,” said study author Changchuan Jiang, MD, resident physician at the Icahn School of Medicine at Mount Sinai. “More importantly here, is that we found that they are more likely to die from cardiovascular disease and pulmonary disease, and their outcome is actually worse than other insurance compared with people without any insurance, which was kind of shocking to us.” - Changchuan Jiang, MD, Resident Physician, Icahn School of Medicine at Mount Sinai Learn more: https://www.curetoday.com/articles/three-types-of-mpns-get-to-know-your-disease-and- treatment-options
U.S. News & World Report – June 18 Can Your Androgen Excess Give You An Edge? — Anna Medaris Miller PCOS, which affects about 15 percent of women of reproductive age, doesn’t always involve excess androgens, and when it does, the increase is typically slight. But even that slight uptick can have devastating consequences. Not only do PCOS and other androgen excess disorders often lead to confidence-shattering side effects like male-pattern hair growth, hair loss, acne and weight gain, but studies have also linked PCOS specifically to serious long-term health problems that are often related to the condition’s effect on insulin resistance and link to obesity. "These conditions were just considered cosmetic problems 30 years ago,” said Andrea Dunaif, MD, chief of the division of endocrinology, diabetes and bone disease for the Mount Sinai Health System. “We now understand that forms of PCOS are associated with an increased risk of diabetes at a very young age and other metabolic problems.” – Andrea Dunaif, MD, Chief, Division of Endocrinology, Diabetes and Bone Disease, Mount Sinai Health System Learn more: https://health.usnews.com/wellness/articles/2018-06-18/can-your-androgen-excess-give-you- an-edge
CBS New York – June 21 Century-Old Vaccine Could Be Major Breakthrough In Diabetes Treatment— Dr. Max Gomez There’s a potential breakthrough in diabetes treatment that could help millions of people around the world. It involves a vaccine for another illness that’s been around for more than a century. The vaccine is called BCG and it’s actually used to immunize children against tuberculosis. It’s been given nearly four billion times over the past century, mostly in China, Africa and South America, but not that often in the U.S., because TB is less common here. Surprisingly, it may also treat diabetes. The study found that when adults with longstanding type one diabetes were given two BCG vaccines a month apart, three years later, their diabetes was reversed, their blood sugar stabilized and stayed stable for up to eight years, so far. “What it seems to show is that the body’s way that it processes glucose is altered when repeated administration of this vaccine,” said David W. Lam, MD, assistant professor of medicine, endocrinology, diabetes and bone disease at the Icahn School of Medicine at Mount Sinai. “This is absolutely a big deal for type one diabetes,” added Dr. Lam. Doctors aren’t ready to call it a cure just yet, but there is a lot of excitement around this – partly because the benefit has lasted for years, and also because the vaccine may stop or slow other autoimmune diseases from rheumatoid arthritis to lupus. -David W. Lam, MD, Assistant Professor, Medicine, Endocrinology, Diabetes, Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://newyork.cbslocal.com/2018/06/21/diabetes-breakthrough/
Scientific American – June 21 Scientists Pinpoint Brain Region That May Be Center Of Alcohol Addiction — Bret Stetka New research published in Science may offer insights into why some humans who drink alcohol develop an addiction whereas most do not. After caffeine, alcohol is the most commonly consumed psychoactive substance in the world. The new research confirms earlier work showing this is true for rats; but it takes things a step further and supports a study design that could help scientists better understand addiction biology, and possibly develop more effective therapies for human addictive behaviors. “In order to develop novel therapeutics for alcoholism it is critical to understand not just the actions of alcohol in the brain, but how those actions may differ between individuals who are vulnerable or resilient to the addictive properties of the drug,” said Paul Kenny, PhD, professor and chair of neuroscience and director of the Drug Discovery Institute at the Icahn School of Medicine at Mount Sinai. This Herculean effort to impressively map out a cellular mechanism that likely contributes to alcohol dependence susceptibility will likely provide important new leads in the search for more effective therapeutics.” Dr. Kenny was not involved in the new research. - Paul J. Kenny, PhD, Professor, Chair, Neuroscience, Director, Drug Discovery Institute, Icahn School of Medicine at Mount Sinai Learn more: https://www.scientificamerican.com/article/scientists-pinpoint-brain-region-that-may-be- center-of-alcohol-addiction/
MedPage Today – June 19 FLT30-ITD Inhibitor Improves Survival In Relapsed AML — Ian Ingram Single-agent treatment with quizartinib improved survival over salvage chemotherapy in adults with relapsed acute myeloid leukemia (AML) and FLT3-internal tandem duplication (ITD), a new study found. “I think the story of FLT3 is an exciting one because that’s a mutation that’s probably seen in approximately a third of patients with acute myeloid leukemia and is a poor prognostic marker,” said John Mascarenhas, MD, associate professor of medicine, hematology and medical oncology and director of the adult leukemia program at the Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai. Dr. Mascarenhas, who was not involved in the study, noted that quizartinib appeared to provide a “modest improvement” and seemed to be as tolerable as traditional chemotherapeutic approaches. “An advantage of having an oral therapy like this is that it makes the patient more ambulatory, which is nice, and less tethered to an IV and an infusion center,” he added. - John O. Mascarenhas, MD, Associate Professor, Medicine, Hematology and Medical Oncology, Director, Adult Leukemia Program, Leader, Clinical Investigation within Myeloproliferative Disorders Program, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai Learn more: https://www.medpagetoday.com/meetingcoverage/eha/73586
Crain’s Health Pulse – June 22 Oscar Expand To Three More States — Jonathan LaMantia SoHo-based health insurer Oscar said it will sell plans to individuals in nine states next year, expanding its exposure to the country’s Affordable Care Act marketplaces as many of the country’s major insurers retreat. The startup has requested approval from state regulators to enter Florida, Arizona, Michigan, while expanding to new areas in Ohio, Tennessee and Texas, where it already sells coverage. As Oscar has entered new markets, it has sought to form partnerships with well-established hospital systems. In New York, its network includes the Mount Sinai Health System, Montefiore Health System and a group of Long Island hospitals. - Mount Sinai Health System Learn more: http://www.crainsnewyork.com/article/20180622/PULSE/180629970/migrant-children- treated-at-city-ers-lack-medical-records-appear-sad
The Philadelphia Inquirer – June 22 How To Know When It’s Time For Hospice — Stacey Burling Hospice provides services aimed at caring for people at the end of life, not curing their ailments. Care is usually provided in people’s homes. Hospice provides some hands-on care, management of pain and symptoms, and drugs and supplies. “We don’t know when people are going to die,” said Diane Meier, MD, professor of geriatrics and palliative medicine at the Icahn School of Medicine at Mount Sinai and director of the Center to Advance Palliative Care at Mount Sinai. “It’s just not given to us.” Doctors are much better, she said, at knowing when patients need extra help. In general, experts such as Dr. Meier look at a “gestalt” that includes functional decline, worsening quality of life, and an increasing number of medical crises. “You look at their day-to-day life compared to six months or a year ago,” she said. - Diane E. Meier, MD, FACP, Professor, Geriatrics and Palliative Medicine, Medicine, Vice Chair, Public Policy, Icahn School of Medicine at Mount Sinai, Director, Center to Advance Palliative Care Learn more: http://www.philly.com/philly/health/how-to-know-when-its-time-for-hospice-20180622.html
HealthiNation – June 21 Six Things You Can Do Right Now To Lower Inflammation In Your Body — Jennifer Lea Reynolds Inflammation plays a role in everything: heart disease, cancer, diabetes, and autoimmune diseases such as rheumatoid arthritis and lupus all have some inflammatory process. “Inflammation can have a negative effect on the health of arteries,” said Mary Ann McLaughlin, MD, associate professor of medicine, cardiology at the Icahn School of Medicine at Mount Sinai and co-director of the women’s cardiac assessment and risk evaluation program at the Mount Sinai Hospital. When inflammatory cells linger in various parts of your body—in blood vessels, for example—it could contribute to dangerous plaques forming. - Mary Ann McLaughlin, MD, Associate Professor, Medicine, Cardiology, Assistant Professor, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Medical Director, Cardiac Health Program, Co-Director, Women’s Cardiac Assessment and Risk Evaluation Program, The Mount Sinai Hospital Learn more: https://www.healthination.com/health/how-to-lower-inflammation
MedPage Today – June 21 Physicians Unhappy With Child Immigrant Detention Policy — Shannon Firth Despite President Trump's executive order to stop immigrant children from being separated from their parents at the border, the physician community has kept up its attacks on the former policy and questioned whether the new version adequately addresses the concerns. Gabrielle L. Shapiro, MD, clinical professor of psychiatry at the Icahn School of Medicine at Mount Sinai, recalled studies of Romanian infants and toddlers separated from their parents. Those children generally have less white matter in their brain and lower IQs. “Our concern about the refugee children… being put into facilities where staff are not allowed to touch them is that the lack of primary attachment figure during early stages of development can lead to long term psychiatric, biological, and social sequelae,” she said. "The youngest children are the biggest concern," because older children already have the experience of developing an attachment to a parent or parent figure. - Gabrielle L. Shapiro, MD, Clinical Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: https://www.medpagetoday.com/pediatrics/generalpediatrics/73634
CNN – June 21 Sunscreen 101: Your Guide To Summer Sun Protection And Sunburn Care — Maddie Bender Skin cancer is the most common cancer in the United States, and UV light exposure is its most preventable risk factor. But according to the U.S. Centers for Disease Control and Prevention, in 2014, over a third of adults reported having sunburn, the skin’s natural response to UV damage, in the previous year. To treat a sunburn, Joshua Zeichner, MD, assistant professor of dermatology at the Icahn School of Medicine at Mount Sinai and director of cosmetic and clinical research in dermatology at The Mount Sinai Hospital, previously said you should take an over-the-counter anti-inflammatory medication such as ibuprofen or aspirin. Then, rinse off with cool water and use a moisturizer over the next few days to replenish dehydrated skin. Make sure to stay hydrated by drinking water and eating hydrating foods, too. - Joshua Zeichner, MD, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director, Cosmetic and Clinical Research in Dermatology, The Mount Sinai Hospital Learn more: https://www.cnn.com/2018/06/21/health/sunscreen-sun-protection-guide/index.html
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 25, 2018 Date: Monday, June 25, 2018 1:02:45 PM Attachments: ATT00001.txt
In the News June 25, 2018
The Aspen Times – June 24 Health Care System Rated Unhealthy At Aspen Ideas Festival — Carolyn Sackariason A panel of medical experts said last week that the financial realities of the health care system are so bleak that widespread change must happen. "What I worry about is that the U.S. can't afford its health care," said Kenneth L. Davis, MD, president and CEO of the Mount Sinai Health System, at the Spotlight Health panel discussion titled “Health System of the Future” as part of the Aspen Ideas Festival. “Whether it's employees, or whether it's employers, or whether it's the government, federal or state, everyone knows we are on a course of catastrophe economically." That's why industry leaders say the approach to health care has to change so that it's a continuum of care that focuses on preventative measures. "We have to get beyond the thinking of the bricks and mortar because what's really exciting is the data mash-up that comes from consumer and patient outcomes that create a data ecosystem," he said. "We really have the opportunity for a new health ecosystem that can embrace the continuity between health and wellness, as well as acute care and sickness." - Kenneth L. Davis, MD, President, CEO, Mount Sinai Health System Learn more: https://www.aspentimes.com/news/local/health-care-system-rated-unhealthy-at-aspen- ideas-festival/
The Wall Street Journal – June 24 Is Robotic Prostate Surgery Better Than Traditional Surgery? Men with prostate cancer face difficult choices. Among them: If they decide to have their prostate removed, how should it be done? The traditional open surgery, in which a surgeon operates through a long skin incision, is starting to be replaced by robotically assisted laparoscopy, with a surgeon operating a robotic system that performs the surgery through smaller incisions. Advocates of robotically assisted prostatectomy argue that the procedure brings a number of advantages. Among them: less blood loss, shorter stays in the hospital and faster recovery times. Ashutosh Tewari, MBBS, MCh, professor and system chair of urology at the Icahn School of Medicine at Mount Sinai, believes the robotic surgery is better. He regularly performs the procedure. “Robotic surgery allows us to make smaller incisions, and move the surgical instruments with virtually 360 degrees of freedom, versus the larger cuts made by traditional surgery. By not cutting deeply into a man’s gut, healing will occur much faster. It also means less pain medication might be needed,” Dr. Tewari said. “The robotic approach gives me better vision, much less bleeding and improved reconstruction ability. These are the key reasons I prefer robotic.” - Ashutosh Tewari, MBBS, MCh, Professor, System Chair, Urology, Icahn School of Medicine at Mount Sinai Learn more: https://www.wsj.com/amp/articles/is-robotic-prostate-surgery-better-than-traditional- surgery-1529892180
MedPage Today – June 25 ‘Hospital At Home’ Cuts Utilization In Pilot Trial— Nicole Lou Hospital-at-home (HaH) care may be a good replacement for traditional inpatient services among some patients who arrive at the emergency department (ED) with an acute condition, a health system reported. In 2014, the Icahn School of Medicine at Mount Sinai was given a Health Care Innovation Award by the Centers for Medicare and Medicaid Services to demonstrate the clinical effectiveness of HaH care bundled with a 30-day postacute period of home-based transitional care. Since then, the institution’s Albert Siu, MD, MSPH, chair emeritus of the Brookdale department of geriatrics and palliative medicine at the Icahn School of Medicine at Mount Sinai, and colleagues observed that several measures did favor HaH care over inpatient hospitalization. - Albert Siu, MD, MSPH, Chair Emeritus, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.medpagetoday.com/publichealthpolicy/medicare/73681 Additional coverage: HealthCare Dive https://www.healthcaredive.com/news/better-outcomes-satisfaction-with-hospital-at- home-care-programs-jama-stu/526458/
CNN – June 21 Herpes Virus May Play Role In Alzheimer’s, Study Says— Jen Christensen Doctor’s don’t know what causes Alzheimer’s disease or the best way to treat it, but they have new evidence to suggest that a common virus may play a role in who develops the condition. In a study published in the journal Neuron, researchers say they’ve found strong evidence to suggest that two strains of the human herpes virus – 6A and 7 – may contribute to the disease that robs people of their memory and cognitive functions. "This is the most compelling evidence ever presented that points to a viral contribution to the cause or progression of Alzheimer's," said study co-author Samuel Gandy, MD, PhD, professor of neurology, psychiatry and associate director of the Alzheimer’s Disease Research Center at the Icahn School of Medicine at Mount Sinai. “While these findings do potentially open the door for new treatment options to explore in a disease where we've had hundreds of failed trials, they don't change anything that we know about the risk and susceptibility of Alzheimer's disease or our ability to treat it today," Dr. Gandy said. - Joel Dudley, PhD, Director, Next Generation Healthcare Institute, Associate Professor, Genetics and Genomic Sciences, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Executive Vice President, Precision Health, Mount Sinai Health System - Samuel Gandy, MD, PhD, Professor, Neurology, Psychiatry, Associate Director, Alzheimer’s Disease Research Center, Icahn School of Medicine at Mount Sinai, Director, The Mount Sinai Center for Cognitive Health and NFL Neurological Care - Benjamin P. Readhead, Icahn Institute for Multiscale Biology, Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai Learn more: https://www.cnn.com/2018/06/21/health/herpes-virus-alzheimers-study/index.html Additional coverage: News 12 The Bronx http://bronx.news12.com/story/38481607/new-study-finds-possible-link-between- herpes-and-alzheimers Eyewitness News http://www.wfsb.com/story/38497192/herpes-virus-may-play-role-in-alzheimers- doctors-say
Drug Target Review – June 25 NIH-funded Study Finds New Evidence That Viruses May Play a Role in Alzheimer’s Disease Analysis of large data sets from post-mortem brain samples of people with and without Alzheimer’s disease has revealed new evidence that viral species, particularly herpesviruses, may have a role in Alzheimer’s disease biology. The authors emphasize that their findings do not prove that the viruses cause the onset or progression of Alzheimer’s. Rather, the findings show viral DNA sequences and activation of biological networks – the interrelated systems of DNA, RNA, proteins and metabolites – may interact with molecular, genetic and clinical aspects of Alzheimer’s. The research group included experts from the Icahn School of Medicine at Mount Sinai. They designed their study to map and compare biological networks underlying Alzheimer’s disease. They began their direct investigation of viral sequences using data from the Mount Sinai Brain Bank and were able to verify their initial observations using datasets from the Religious Orders Study, the Memory and Aging Project and the Mayo Clinic Brain Bank. - Icahn School of Medicine at Mount Sinai Learn more: https://www.drugtargetreview.com/news/32603/nih-funded-study-finds-new-evidence-that- viruses-may-play-a-role-in-alzheimers-disease/
Bloomberg – June 19 Bloomberg Markets: Data Is Key To Medical Care — Carol Massar Eric Schadt, PhD, dean of precision medicine, professor of genetics and genomic sciences at the Icahn School of Medicine at Mount Sinai and founder and chief executive officer of Sema4, discusses building a database of genetic and medical information to treat disease and provide medical care. “The end goal is to find more accurate and reliable predictions around the state of an individual’s health and wellness. With better predicting and better guiding of actionable care to the physician, they can elucidate what is going on with the patient to provide better care and treatments,” Dr. Schadt said. - Eric E. Schadt, PhD, Dean, Precision Medicine, Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Founder and CEO, Sema4 Learn more: https://www.bloomberg.com/news/audio/2018-06-19/bloomberg-markets-data-is-key-to- medical-care
BBC Radio – June 22 Sema4: Medical Data Helps To Improve Diagnosis Data could potentially be lifesaving. Eric Schadt, PhD, dean of precision medicine, professor of genetics and genomic sciences at the Icahn School of Medicine at Mount Sinai and founder and CEO of Sema4, is taking medical data from patients and using it to improve diagnoses, treatments given to patients, and prevent diseases all through deep data analysis. “Data donation is a patient or even a consumer making available data that’s generated on them in the context of their medical care for researchers to pursue a better understanding of disease. This is an individual contributing information for the greater research good, which we also view as having a favorable impact on the patient,” Dr. Schadt said. - Eric E. Schadt, PhD, Dean, Precision Medicine, Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Founder and CEO, Sema4 Learn more: No web link available.
MedPage Today – May 18 Using Biology Of Atopic Dermatitis To Improve Therapy — Charles Bankhead Following the therapeutic model of psoriasis, treatment for atopic dermatitis (AD) increasingly focuses on identifying and targeting specific molecules involved in etiology and pathogenesis, experts said. The potential for applying the psoriasis model to AD did not become apparent until recently, as AD is a more complex condition, involving abnormalities in both immune response and the skin barrier, said Emma Guttman-Yassky, MD, PhD, professor of dermatology, clinical immunology and medicine, vice chair of research in the department of dermatology, and director of the Center for Excellence in Eczema in the Laboratory of Inflammatory Skin Diseases at the Icahn School of Medicine at Mount Sinai, at the American Academy of Dermatology meeting. "Unlike psoriasis, AD cannot be explained by a single cytokine pathway," said Dr. Guttman-Yassky. "But the consistent cytokine axis activated across all phenotypes appears to be Th2. Thus far, dupilumab shows similar in intrinsic/extrinsic and filaggrin- positive and negative AD phenotypes." - Emma Guttman-Yassky, MD, PhD, The Sol & Clara Professor, Dermatology, Clinical Immunology, Medicine, Vice Chair, Research, Department of Dermatology, Director, The Center for Excellence in Eczema, Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai Learn more: https://www.medpagetoday.com/clinicalfocus/atopicdermatitis/72634? eun=g8319026d19r&xid=NLMPT_Atopic_Dermatitis&utm_source=WhatCounts&utm_medium=email
MD Magazine – June 24 Girls With Type 1 Diabetes More Likely To Have Suicidal Ideation — Kevin Kunzmann Though the threat of suicide ideation (SI) may be a greater expressed risk in children suffering from debilitating disease, researchers recently discovered that children with type 1 diabetes (T1D) do not have greater SI rates than the general population. The data was presented at the 2018 American Diabetes Association 78th Annual Scientific Sessions, this week. Andrea Dunaif, MD, chief of the division of endocrinology, diabetes and bone disease for the Mount Sinai Health System, noted that one of the greater drivers of worsened quality of life in females with diabetes in polycystic ovary syndrome (PCOS) is obesity. “I think there really need to be a much more widespread attention to looking at quality of life issues,” she said. “Women have a greater risk for depression, and have a much higher prevalence of depression than men do.” These rates similarly extend into suicidal behavior. “I think it behooves physicians to explore that in more detail,” added Dr. Dunaif. – Andrea Dunaif, MD, Chief, Division of Endocrinology, Diabetes and Bone Disease, Mount Sinai Health System Learn more: http://www.mdmag.com/conference-coverage/ada-2018/girls-with-type-1-diabetes-more- likely-to-have-suicidal-ideation
Bleacher Report – June 24 Hall Of Fame QB Jim Kelly Released From Hospital After Successful Surgery On Jaw — Joseph Zucker Hall of Fame quarterback Jim Kelly was discharged from a New York hospital Friday after undergoing surgery on his jaw. Doctors performed the procedure to place permanent dentures in Kelly’s upper jaw. Kelly will return for the surgery in September, at which time the dentures will be implanted. Jill, Kelly’s wife said, “Everything is moving forward as planned. Jim has some swelling and healing that needs to take place after this recent procedure. We are very thankful for the team of Mount Sinai doctors taking care of Jim. We appreciate the continued prayer and support and trust God with everything.” - Mark L. Urken, MD, Professor, Otolaryngology, Icahn School of Medicine at Mount Sinai, Head and Neck Surgeon, Mount Sinai West Learn more: https://bleacherreport.com/articles/2782769-hall-of-fame-qb-jim-kelly-released-from- hospital-after-successful-surgery-on-jaw Additional coverage: WGRZ News https://www.wgrz.com/article/news/local/bills-hof-quarterback-jim-kelly-doing-well-after- follow-up-surgery/71-566294733 Sports Illustrated https://www.si.com/nfl/2018/06/24/jim-kelly-hall-of-fame-bills-qb-cancer-leaves- hospital Buffalo News https://buffalonews.com/2018/06/22/jim-kelly-discharged-from-hospital-after-follow-up- surgery/ Yahoo Sports https://www.yahoo.com/amphtml/sports/jim-kelly-released-hospital-successful-follow- surgery-jaw-035528039.html
The New York Times – June 24 Opinion: When Pregnant Women Face Workplace Bias Shari Lusskin, MD, clinical professor of psychiatry, obstetrics, gynecology and reproductive science at the Icahn School of Medicine at Mount Sinai writes, “This is an era in which women’s reproductive rights are being systematically undermined within the larger context of denying health care to millions of Americans. The strain of working while dealing with morning sickness and other physical demands of pregnancy is compounded by the threat of demotion or dismissal in businesses that do not make appropriate and humane allowances for pregnancy.” She added that the resulting stress puts women at risk for anxiety and depression, conditions that can have a negative effect not just on the pregnant woman and her family but also on the developing baby. “As a reproductive psychiatrist, I have seen this play out in many women’s lives, and the fact that little has changed in the more than 20 years that I’ve been doing this work is outrageous.” - Shari I. Lusskin, MD, Clinical Professor, Psychiatry, Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai Learn more: https://www.nytimes.com/2018/06/24/opinion/pregnant-women-workplace-bias.html
Everyday Health – June 22 How To Safely Use A Neti Pot — Genevieve Scarano If you feel like your allergies, sinus, and upper respiratory problems are escalating, it might be time to try a nasal irrigation device, such as a neti pot. According to the FDA, neti pots are nasal irrigation devices that use salt water or saline solution to moisten nasal passages and clean out mucus. There are many types of neti pots on the market and they can be purchased at pharmacies, supermarkets, and online retailers. “Saline irrigations provide a non-pharmacologic way to cleanse the nose and help with symptoms of allergies, congestion, nasal drainage, and pressure,” said Anthony Del Signore, MD, assistant professor of otolaryngology at the Icahn School of Medicine at Mount Sinai and director of rhinology and endoscopic skull base surgery at Mount Sinai Union Square. “It works by reducing the allergic load within the nasal cavity by washing out the allergens and inciting factors leading to the localized allergic reaction.” Dr. Del Signore said neti pots, can also help with chronic sinus issues, since they minimize the bacterial load within the nasal cavity. - Anthony Del Signore, MD, Assistant Professor, Otolaryngology, Icahn School of Medicine at Mount Sinai, Director, Rhinology and Endoscopic Skull Base Surgery, Mount Sinai Union Square Learn more: https://www.everydayhealth.com/reviews/how-safely-use-neti-pot/
New York Magazine: The Strategist – June 22 How To Clean Your Ears (Properly), According To ENTs— Lori Keong Cleaning your ears is often a private, gross moment between you and a Q-tip, but according to ENTs, if you know what’s good for you, you’d stop fussing with your ears completely. Maura Cosetti, MD, assistant professor of otolaryngology, neurosurgery at the Icahn School of Medicine at Mount Sinai and director of the Cochlear Implant Center at the New York Eye and Ear Infirmary of Mount Sinai – explains that wax already self-regulated, and even carries health benefits. “Having wax is a sign of a healthy ear. It combines lubricating, antibacterial, and even antifungal properties. It’s not like brushing your teeth, or something you have to think about cleaning all the time. It’s quite the opposite.” - Maura K. Cosetti, MD, Assistant Professor, Otolaryngology, Neurosurgery, Icahn School of Medicine at Mount Sinai, Director, The Cochlear Implant Center, Ear Institute, New York Eye and Ear Infirmary of Mount Sinai Learn more: http://nymag.com/strategist/article/how-to-clean-your-ears.html
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 26, 2018 Date: Tuesday, June 26, 2018 3:16:01 PM Attachments: ATT00001.txt
In the News June 26, 2018
Modern Healthcare – June 25 Mount Sinai’s Hospital-At-Home Model Improves Patient Outcomes — Michelle Castellucci Patients who participated in a hospital-at-home model crafted by the Icahn School of Medicine at Mount Sinai reported shorter readmissions, fewer emergency department visits and better patient experience than those with traditional hospital stays, according to a new study. The findings, published in JAMA Internal Medicine, come as the CMS considers adding an iteration of the model to the Medicare program. "We always expected the model would be tweaked because it would be implemented nationally,” said Albert Siu, MD, MSPH, an author of the study and chair emeritus of the Brookdale Department of geriatrics and palliative medicine at the Icahn School of Medicine at Mount Sinai. “We look forward to working with the CMS in making this available to Medicare beneficiaries.” This 30-day post-acute period is unique. No other hospital-at-home model includes a post-acute period, Dr. Siu added. - Albert Siu, MD, MSPH, Chair Emeritus, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai Learn more: http://www.modernhealthcare.com/article/20180625/TRANSFORMATION03/180629954? utm_source=modernhealthcare&utm_medium=email&utm_content=20180625-TRANSFORMATION03- 180629954&utm_campaign=dose Additional coverage: AJMC News https://www.ajmc.com/newsroom/hospitalathome-bundled-program-associated-with- better-clinical-outcomes-patient-experiences Crain’s Health Pulse: http://www.crainsnewyork.com/article/20180626/PULSE/180629940/how-audicus- is-disrupting-the-hearing-aid-business (Subscription required)
Contagion Live – June 25 Herpevirus Could Potentially Be Linked To Alzheimer’s Disease — Michaela Fleming Researchers from the Icahn School of Medicine at Mount Sinai have found that herpesviruses are more abundant in the brains of Alzheimer’s patients and suggest that they may play a role in regulatory genetic networks that lead to the disease. In a large-scale analysis published in Neuron, researchers looked at data from 3 major brain banks provided by National Institutes of Health's Accelerating Medicines Partnership -- Alzheimer's Disease (AMP-AD) consortium. Although initially, they were looking for drugs to repurpose for Alzheimer’s treatment, the data directed them towards investigating viral biology themes. "Previous studies of viruses and Alzheimer's have always been very correlative. But we were able to do statistical causal inference testing and more sophisticated analysis, which allowed us to identify how the viruses are directly interacting with or co-regulating or being regulated by Alzheimer's genes,” said co-senior author Joel Dudley, PhD, director of the Next Generation HealthCare Institute and Executive Vice President for Precision Health at the Mount Sinai Health System. - Joel Dudley, PhD, Director, Next Generation Healthcare Institute, Associate Professor, Genetics and Genomic Sciences, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Executive Vice President, Precision Health, Mount Sinai Health System - Samuel Gandy, MD, PhD, Professor, Neurology, Psychiatry, Associate Director, Alzheimer’s Disease Research Center, Icahn School of Medicine at Mount Sinai, Director, The Mount Sinai Center for Cognitive Health and NFL Neurological Care - Benjamin P. Readhead, Icahn Institute for Multiscale Biology, Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai Learn more: http://www.contagionlive.com/news/herpesvirus-could-potentially-be-linked-to-alzheimers- disease Additional coverage: Outer Places https://www.outerplaces.com/science/item/18653-herpes-virus-alzheimers-disease
Healio: Infectious Diseases In Children – June 25 Nasal Brush Successfully Tests For Genetic Biomarkers Of Mild, Moderate Asthma — Katherine Bortz A genetic biomarker of asthma collected from a nasal swab can accurately diagnose asthma in patients with mild to moderate symptoms. The identification of this biomarker using the swab can also differentiate between asthma and other respiratory diseases, including allergic rhinitis, upper respiratory infections and cystic fibrosis. “Our nasal classifier of asthma represents a novel path to diagnosing asthma with a simple nasal brush,” said senior author, Supinda Bunyavanich, MD, MPH, associate professor of genetics and genomic sciences, and pediatrics at the Icahn School of Medicine at Mount Sinai. “It takes seconds to perform a nasal brushing, and interpretation of data gained from this brushing can be automated based on an algorithm we identified, yielding an output of asthma or no asthma.” - Supinda Bunyavanich, MD, MPH, Associate Professor, Genetics and Genomic Sciences, Pediatrics, Icahn School of Medicine at Mount Sinai - Gaurav Pandey, PhD, Assistant Professor, Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai Learn more: https://www.healio.com/pediatrics/allergy-asthma-immunology/news/online/%7B445c23b2- 60db-4855-a6e2-4b43a9a20114%7D/nasal-brush-successfully-tests-for-genetic-biomarkers-of-mild- moderate-asthma
U.S. News & World Report – June 26 Mount Sinai Kravis Children's Hospital Nationally Ranked in 5 Children's Specialties Mount Sinai Kravis Children's Hospital, part of The Mount Sinai Hospital, is in Manhattan, between the Upper East Side and Harlem. At about 150 patients a day, the number of admissions is in the average range. The hospital's Nurse Magnet recognition indicates its nursing excellence status. Patients and their families can learn more about specific medical conditions at the hospital's library and from the full-time resource staff and medical librarian - Mount Sinai Kravis Children’s Hospital Learn more: https://health.usnews.com/best-hospitals/area/ny/mount-sinai-kravis-childrens-hospital- PA6213140 Additional coverage: Daily News: http://www.nydailynews.com/new-york/ny-metro-childrens-hospitals-20180620-story.html
U.S. News & World Report – June 26 Where Are They Now? Stories of Adult Survivors of Pediatric Heart Surgery — Anna Medaris Miller When Patrick Lowery was born, he had 10 fingers and 10 toes, wailed upon delivery and, by all other accounts, appeared a normal, healthy baby. Twenty-four hours later, he was anything but. Lowery was hemorrhaging and having seizures, and doctors detected his kidneys were failing. They didn't think he was going to survive. Lowery had a heart defect called coarctation of the aorta, which means the blood vessel that carries blood away from the heart was narrowing Lowery is among a new group of adults who are survivors of pediatric heart surgeries. Before the 1970s and 1980s, many such surgeries didn't exist and babies born with congenital heart defects didn't make it to adulthood; many didn't even make it to their first birthdays, says Peter Pastuszko, MD, chief of pediatric cardiovascular surgery and director of pediatric cardiovascular services at Mount Sinai Health System who operated on Charlie. Since then, the procedures have advanced such that 90-plus percent of children are surviving them compared to about 50 percent in the '80s and '90s. "We've gotten so much better at taking care of those kids," Dr. Pastuszko says. - Peter Pastuszko, MD, Chief, Pediatric Cardiovascular Surgery, Director, Pediatric Cardiovascular Services, Mount Sinai Health System Learn more: https://health.usnews.com/health-care/articles/2018-06-26/where-are-they-now-stories-of- adult-survivors-of-pediatric-heart-surgery
New York Daily News – June 26 Long Island Teen With Crohn's Disease Partners With NBA Star Larry Nance Jr. To Launch Charity --- Reuven Blau Noah Weber, 14, has partnered with Larry Nance Jr. to launch a charity to bring awareness to those suffering from Crohn’s disease Noah Weber was 11 when he began to feel lethargic during sporting events with classmates. “I wasn’t able to do as much as my friends,” Noah also suddenly stopped growing. Enter Marla Dubinsky, MD, chief of pediatric gastroenterology and hepatology at the Kravis Children’s Hospital at Mount Sinai and co-director of the Susan and Leonard Feinstein IBD clinical center at The Mount Sinai Hospital She ordered a special kind of magnetic-resonance imaging test known as an MR Enterography. The test was conclusive: Noah had Crohn’s disease, a chronic inflammatory ailment of the gastrointestinal tract. Noah’s surgery has been a resounding success, and Noah has a great long-term prognosis, according to Dr. Dubinsky. “The key is finding the right family physician team,” she says. “It’s all about how can we build resiliency when they are getting derailed by a lifelong illness - Marla C. Dubinsky, MD, Professor, Pediatrics, Gastroenterology, Icahn School of Medicine at Mount Sinai, Chief, Pediatric Gastroenterology and Hepatology, Kravis Children’s Hospital at Mount Sinai, Co-Director, The Susan and Leonard Feinstein Inflammatory Bowel Disease Clinical Center, Mount Sinai Hospital Learn more: http://www.nydailynews.com/new-york/ny-metro-mt-sinai-20180619-story.html? outputType=amp
The Irish Times – June 25 Ireland Can Help UN To Stop Assad Manipulating Humanitarian Aid— Annie Sparrow, MD, MPH This week, Ireland takes over leadership of the international donor group that supports the United Nations Office for the Co-ordination of Humanitarian Affairs (OCHA). OCHA manages humanitarian crises, determines the global humanitarian budget, and allocates funds from donor governments. One of its biggest challenges is Syria. The conflict and the humanitarian crisis are the result of Assad’s violent repression of civilians seeking basic human rights, writes Annie Sparrow, MD, MPH, MBBS, assistant professor of population health science and policy, preventive medicine, and pediatrics with the Arnhold Institute of Global Health at the Icahn School of Medicine at Mount Sinai. - Annie Sparrow, MD, MPH, MBBS, Assistant Professor, Population Health Science and Policy, Preventive Medicine, Pediatrics, Icahn School of Medicine at Mount Sinai Learn more: https://www.irishtimes.com/opinion/ireland-can-help-un-to-stop-assad-manipulating- humanitarian-aid-1.3543303
MD Magazine – June 25 Andrea Dunaif, MD: PCOS Prevalence In Women With Type 2 Diabetes— Kevin Kunzmann The large-scale, transparent health issues of the United States are beneficial to researchers — if not just because of patient sample size opportunities. Studies and analysis presented at the 2018 American Diabetes Association 78th Scientific Sessions this week featured U.S.-based trials that sometimes included thousands of patients with diabetes being treated in real-world settings. Andrea Dunaif, MD, chief of the division of endocrinology, diabetes and bone disease for the Mount Sinai Health System, said her interests in sessions had particularly leaned towards those focused on polycystic ovary syndrome in women. Dr. Dunaif noted that much of the newest data in PCOS has brought clearer answers to its characteristics and association to conditions such as type 2 diabetes. Though more work needs to be done in clinical settings both in and outside of the United States, Dr. Dunaif found take-home messages pertaining to patient screening. – Andrea Dunaif, MD, Chief, Division of Endocrinology, Diabetes and Bone Disease, Mount Sinai Health System Learn more: http://www.mdmag.com/conference-coverage/ada-2018/andrea-dunaif-md-pcos-prevalence- in-women-with-type-2-diabetes
The ASCO Post – June 25 Regular Mammograms Linked To Less Aggressive Treatment In Patients With Breast Cancer— Chase Doyle A study evaluating the impact of breast cancer screening has shown that the benefits of regular mammograms extend well beyond reduced mortality. According to data presented at the American Society of Breast Surgeons (ASBrS) 2018 Annual Meeting, women with breast cancer who underwent regular mammograms were diagnosed with earlier-stage disease and were significantly less likely to require aggressive treatment compared to those who delayed or never underwent screening. “This study is notable because research on the impact of screening mammography typically focuses on its relationship to breast cancer mortality, not tumor stage and the therapies required,” said Elisa Port, MD, FACS, chief of breast surgery and director of the Dubin Breast Center at The Mount Sinai Hospital. “Although regular mammograms unquestionably have been demonstrated to reduce mortality, this study shows they also are associated with less complex treatment regimens, with less risk of undesirable side effects that can diminish a survivor’s ongoing quality of life.” - Elisa Port, MD, FACS, Director of the Dubin Breast Center and Chief of Breast Surgery, The Mount Sinai Hospital Learn more: http://www.ascopost.com/issues/june-25-2018/regular-mammograms-linked-to-less- aggressive-treatment/
The Fix – June 25 HealthCare Pros Talk Unintended Consequences Of Addressing Opioid Crisis— Kelly Burch The opioid epidemic has drawn more political and media attention than any other public health crisis in recent memory, but healthcare professionals say that the focus on preventing opioid-related deaths is having unintended consequences for patients dealing with other conditions including cancer, chronic pain and other forms of substance use disorder. One of the biggest concerns is that patients are being taken off their opioids too quickly, which can increase physical symptoms of withdrawal and leave patients feeling overwhelmed by the idea of quitting. R. Sean Morrison, MD, professor and chair of the Brookdale department of geriatrics and palliative medicine at the Icahn School of Medicine at Mount Sinai, said that he is increasingly seeing hospice patients unable to get the opioid drugs they need to make their end of life more bearable. “Almost every patient I have prescribed for recently has either a) run into pharmacies that no longer carry common opioids; b) cannot receive a full supply; and c) worst of all had their mail order pharmacy refuse to fill or have had arbitrary and non-science based dose or pill limits imposed,” he said. - R. Sean Morrison, MD, Professor, Chair, Ellen and Howard C. Katz, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.thefix.com/healthcare-pros-talk-unintended-consequences-addressing-opioid- crisis
Science Trends – June 25 What Is CBD Oil? — Daniel Nelson Cannabidiol oil (CBD) is an oil made from cannabidiol, one of the active chemical compounds found within cannabis, which reacts with the cannabinoid receptors in the brain and effects the release of neurotransmitters. CBD doesn’t have the intoxicating effect on the brain that THC does but it may have the effect of treating epilepsy and inhibited anxiety and disordered thinking. Research conducted by Yasmin Hurd, PhD, professor of psychiatry, neuroscience, pharmacology and systems therapeutics at the Icahn School of Medicine at Mount Sinai, chair of Ward-Coleman Translational Neuroscience and director of the Center for Addictive Disorders at the Mount Sinai Health System, implies that CBD could help treat people with addiction. Dr. Hurd explains, “When we looked at CBD, it decreased heroin- seeking behaviors. There’s no miracle drug, but this could be helpful for at least some aspects of craving.” - Yasmin Hurd, PhD, Professor, Psychiatry, Neuroscience, Pharmacology, Systems Therapeutics, Icahn School of Medicine at Mount Sinai, Chair, Ward-Coleman Translational Neuroscience, Director of the Center for Addictive Disorders, Mount Sinai Health System Learn more: https://sciencetrends.com/what-is-cbd-oil/
Eye World – June 25 Innovations In Challenging Glaucoma Cases— Rich Daly Glaucoma specialists agree that emerging treatments offer growing hope for their most challenging cases. Among the most challenging glaucoma cases seen by Nathan Radcliffe, MD, clinical assistant professor of ophthalmology at the Icahn School of Medicine at Mount Sinai, are cases that don’t respond to several glaucoma surgeries. “Usually when you’re on your third or fourth glaucoma surgery, you’re running probabilities that these eyes are going to have some complication with each surgery. We always think one surgery ahead so if this surgery doesn’t work, what am I doing next?” he added. “In my practice, about one-third of the people I operate on only have the one eye,” Dr. Radcliffe said. “They lost their other eye before I met them—often from glaucoma—so there is little room for error.” - Nathan Radcliffe, MD, Clinical Assistant Professor, Ophthalmology, Icahn School of Medicine at Mount Sinai Learn more: https://www.eyeworld.org/innovations-challenging-glaucoma-cases
Eye World – June 25 An Inside Look At Outflow Drugs For Glaucoma — Maxine Lipner Two new medications for lowing IOP are gaining traction in the glaucoma sector, drugs that can increase the outflow of aqueous through the drainage tissue. These unique medications, latanoprostene bunod, which became available in late 2017, and netarsudil, which emerged in early 2018, offer new options for practitioners, according to Janet Serle, MD, professor of ophthalmology and director of the glaucoma clinical and research fellowship at the Icahn School of Medicine at Mount Sinai. In patients with glaucoma, the trabecular pathway is the site of the diseased tissue, Dr. Serle explained. “The changes in this tissue lead to elevated IOP,” she said. “Medications that act directly on this critical tissue to enhance outflow are very important as it is possible that instituting therapy early in the disease and protecting these tissues from chronic changes may reduce the long-term severity of glaucoma.” - Janet B. Serle, MD, Professor, Ophthalmology, Director, Glaucoma Clinical and Research Fellowship, Icahn School of Medicine at Mount Sinai Learn more: https://www.eyeworld.org/inside-look-outflow-drugs-glaucoma
Eye World – June 25 Study Shows Little Effect From Omega-3 Fatty Acids — Rich Daly The results of the Dry Eye Assessment and Management (DREAM) study were recently published in the New England Journal of Medicine. This was a multicenter, double-blinded prospective clinical trial with dry eye patients randomly assigned to omega-3 fatty acids versus olive oil placebo for 12 months. Omega-3 fatty acids have anti-inflammatory properties and are abundant in some plant oils (walnuts, flaxseed, and canola) and fish. It is commendable that Penny Asbell, MD, professor of ophthalmology and director of the Cornea Service and Refractive Surgery Center at the Icahn School of Medicine at Mount Sinai, have successfully designed and conducted this study. - Penny Asbell, MD, Professor, Ophthalmology, Director, The Cornea Service and Refractive Surgery Center, Icahn School of Medicine at Mount Sinai Learn more: https://www.eyeworld.org/study-shows-little-effect-omega-3-fatty-acids
POZ – June 25 Coinfection Connection — Benjamin Ryan Hep C, an insidious infection of the liver for which there is no vaccine, transmits readily – much more so than HIV – through the sharing of needles, syringes and other infection-drug paraphernalia. Considerable research has indicated that when HIV remains untreated by ARVs, it accelerates HCV- related liver damage in particular. Whether HIV hastens much harm to the liver among those on successful ARV treatment has lately become a rather controversial topic, according to Daniel Fierer, MD, associate professor of medicine and infectious diseases at the Icahn School of Medicine at Mount Sinai. After all, controlling HIV is associated with reduced risk of liver disease. - Daniel Fierer, MD, Associate Professor, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: https://www.poz.com/article/coinfection-connection
Daily Mail – June 25 Marijuana Addiction Is Real: Four Million Americans Hooked On Cannabis Itself And There Is No Treatment — Natalie Rahhal Marijuana is now legal - for either medical or recreational use – in 31 states and strains are getting stronger and stronger. Its legalization has buoyed by ever-growing evidence that it does not have debilitating health consequences. Yet the National Institutes of Health estimate that four million Americans are addicted to marijuana. “One way to look at marijuana is the way we look at something like alcoholic beverages,” suggested Edwin Salsitz, MD, assistant clinical professor at the Icahn School of Medicine at Mount Sinai and addiction specialist at Mount Sinai Beth Israel. “Most people are social users and don’t run into any trouble with it, but about 20 million people in the U.S. are alcoholic dependent. There are groups of people that do develop an addiction to marijuana in the same way one can with alcohol.” - Edwin Salsitz, MD, Assistant Clinical Professor, Psychiatry, Icahn School of Medicine at Mount Sinai, Addiction Specialist, Mount Sinai Beth Israel Learn more: http://www.dailymail.co.uk/health/article-5883793/Marijuana-addiction-real-Forget- gateway-drug-fears-4-million-Americans-hooked-weed.html
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 27, 2018 Date: Wednesday, June 27, 2018 12:03:31 PM Attachments: ATT00001.txt
In the News June 27, 2018
Medscape – June 26 Hospital-At-Home Care Improved Outcomes, Patient Satisfaction — Tara Haelle Patients receiving a new model of hospital-at-home (HaH) care had better outcomes, greater satisfaction, and no increased rate of adverse events compared with similar patients who received traditional inpatient care, a study has found. Length of inpatient care stay, readmission rates, and emergency department revisits were nearly half as high in the HaH group compared with traditional inpatient care, the researchers write. Alex D. Federman, MD, MPH, professor of medicine and general internal medicine at the Icahn School of Medicine at Mount Sinai, and colleagues published their findings in JAMA Internal Medicine. HaH care involved a physician or nurse practitioner providing acute care services at the patient's home, including exam, vital signs, illness monitoring, intravenous fluids, wound care, and patient education. - Alex D. Federman, MD, Professor, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai - Albert Siu, MD, MSPH, Chair Emeritus, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.medscape.com/viewarticle/898538 Additional coverage: Doctors Lounge https://www.doctorslounge.com/index.php/news/pb/81437 Medical Xpress https://medicalxpress.com/news/2018-06-clinical-outcomes-patient-vastly-hospital.html McKnight’s Long-Term Care News https://www.mcknights.com/news/home-based-acute-care-pilot- drops-transfers-to-skilled-nursing-facilities/article/776009/
New York City Patch – June 26 Five NYC Children’s Hospitals Ranked Among Nation’s Best: U.S. News — Brendan Krisel Several New York City hospitals earned high marks on the U.S. News & World Report’s 12th annual “Best Children’s Hospitals” rankings. The rankings looked at ten pediatric specialties. In New York City, Mount Sinai, New York Presbyterian, Montefiore, the Hospital for Special Surgery and Memorial Sloan Kettering all made the list. - Mount Sinai Kravis Children’s Hospital Learn more: https://patch.com/new-york/new-york-city/new-york-citys-best-childrens-hospitals-u-s-news
MD Magazine – June 26 Trends In Insulin Pen Priming For Patients With Type 1 Diabetes — Matt Hoffman Grenye O’Malley, MD, chief endocrine fellow in the division of endocrinology, diabetes and bone disease at the Icahn School of Medicine at Mount Sinai, presented her research at the American Diabetes Association’s 78th Annual Scientific Sessions, about her study data on insulin pen priming for patients with type 1 diabetes that require multiple daily injections (MDIs). She also talked about the need to improve communication with these patients to better meet their needs and relieve them of burden. “The majority of type 1 diabetics use multiple daily injections, and it's a huge area that we just don't know anything about. I think that was probably the most surprising thing to me going through the study,” said Dr. O’Malley. - Grenye O’Malley, MD, Chief Endocrine Fellow, Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: http://www.mdmag.com/conference-coverage/ada-2018/trends-in-insulin-pen-priming-for- patients-with-type-1-diabetes
Healthline – June 23 Rheumatoid Arthritis And Huntington’s Diseases May Share A Common Link — Ashley Boynes- Shuck Scientists from the Icahn School of Medicine at Mount Sinai and the University of California San Diego School of Medicine have discovered an apparent epigenetic overlap between the origins of Huntington’s disease and that of rheumatoid arthritis (RA). The researchers shared their findings in the journal Nature Communications. Using cutting-edge analytical tools, the scientists analyzed the epigenomic landscape of RA and compared it to other conditions. The recent connection between the epigenetic origins of RA and Huntington’s may shed more light on this area of research and disease treatment. Discoveries like this may also yield more unexpected novel therapeutic drug targets for many diseases such as rheumatoid arthritis, which is sometimes treated by targeted therapies and precision medicine. - Icahn School of Medicine at Mount Sinai Learn more: https://www.healthline.com/health-news/ra-and-huntingtons-common-link tctMD – June 26 Trade-Offs Between Self-Expanding And Balloon-Expandable Valves In Very Large Annuli — Michael O’Riordan For a patient with a large aortic annulus undergoing trans catheter aortic valve replacement, a new study suggests there are different risks and benefits when it comes to the use of self-expanding and balloon- expandable transcatheter valves. “Both devices were equally safe, but the bottom line is that it comes down to what the site is comfortable using,” said lead investigator Gilbert H. Tang, MD, senior faculty of cardiovascular surgery at the Icahn School of Medicine at Mount Sinai and surgical director of the Structural Heart Program for the Mount Sinai Health System. “I think both valves perform equally well— Sapien 3 and Evolut R—with the caveat being that at least in our study the Evolut R had higher incidence of new persistent left bundle branch block and new pacemaker implantation.” - Gilbert H. Tang, MD, Senior Faculty, Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai, Surgical Director, The Structural Heart Program, Mount Sinai Health System Learn more: https://www.tctmd.com/news/trade-offs-between-self-expanding-and-balloon-expandable- valves-very-large-annuli
MD Magazine – June 26 Andrea Dunaif, MD: Cardiovascular Disease In Women — Kevin Kunzmann Cardiovascular disease (CVD) is an overwhelming presence in U.S. health care. According to the American Diabetes Association (ADA), CVD is up to four times more prevalent in adults with diabetes — a condition currently affecting about 30 million Americans. While attending the 2018 ADA 78th Annual Scientific Sessions, Andrea Dunaif, MD, chief of the division of endocrinology, diabetes and bone disease for the Mount Sinai Health System, discussed how the comorbidities and conditions most closely associated with diabetes affect female patients. Of course, none are more crucial than CVD. “But even more concerning, physicians who care for these women are not giving attention to modifiable risk factors in women that they do in men,” she said. Dr. Dunaif discussed all the elements that have led to an underwhelming national response to CVD in women. – Andrea Dunaif, MD, Chief, Division of Endocrinology, Diabetes and Bone Disease, Mount Sinai Health System Learn more: http://www.mdmag.com/conference-coverage/ada-2018/andrea-dunaif-md-cardiovascular- disease-in-women
MD Magazine – June 26 Grenye O’Malley, MD: The Importance Of Dieticians In Diabetes —Matt Hoffman Grenye O’Malley, MD, chief endocrine fellow in the division of endocrinology, diabetes and bone disease at the Icahn School of Medicine at Mount Sinai, talked at the American Diabetes Association’s 78th Annual Scientific Sessions about the role that dieticians can play in the management of diabetes. She also spoke about how although dieticians provide a skill set outside of the physician’s training, unfortunately, not enough doctors have the available resources to always have them included on their treatment team. - Grenye O’Malley, MD, Chief Endocrine Fellow, Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: https://www.youtube.com/watch?v=qnAp6U7pw44
MD Magazine – June 26 Alternative Sleep Apnea System Receives FDA Approval To Market — Cecilia Pessoa Gingerich The US Food and Drug Administration (FDA) has granted a de novo application to market the CURVE Positive Airway Pressure delivery system for the treatment of obstructive sleep apnea (OSA). The FRESCA Medical, Inc system includes a dedicated flow generator, a light and ergonomic hose for air delivery, and a nasal pillow patient interface, and is intended for use by adult patients weighing over 66 lbs. "CPAP compliance continues to be a struggle for millions of people," said the largest enroller in the FRESCA study, Gary K. Zammit, PhD, assistant clinical professor of psychiatry at the Icahn School of Medicine at Mount Sinai. “Additional options for treating obstructive sleep apnea could ultimately drive improvements in compliance and clinical outcomes." - Gary K. Zammit, PhD, Assistant Clinical Professor, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: http://www.mdmag.com/medical-news/alternative-sleep-apnea-system-receives-fda- approval-to-market Additional coverage: Medical Devices Business Review http://patientmonitoring.medicaldevices-business- review.com/news/fda-authorizes-fresca-medical-to-market-new-positive-airway-pressure-delivery- system-to-treat-osa-260618-6220162
HealthDay – June 26 Flight Attendants Show Higher Cancer Risks — Amy Norton Flight attendants may face higher-than-average risks of breast and skin cancers, a new study finds -- though the reasons why aren't yet clear. Researchers found that compared with women in the general U.S. population, female flight attendants had a 51 percent higher rate of breast cancer. Meanwhile, their rates of melanoma and non-melanoma skin cancers were about two to four times higher, respectively. It’s possible that there are factors unrelated to flight attendant’s jobs, said Paolo Boffetta, MD, professor of medicine, oncological sciences, hematology and medical oncology, and associate director of population sciences at the Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai. “For example, they may have more UV sun exposure because of their opportunity to travel,” Dr. Boffetta, who was not involved in the study, added. In addition, he said women on air crews may put off having children or have fewer kids, compared with other women. And reproductive factors like that are associated with the risk of breast cancer. - Paolo Boffetta, MD, Professor, Medicine, Oncological Sciences, Hematology and Medical Oncology, Associate Director, Population Sciences, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai Learn more: https://consumer.healthday.com/cancer-information-5/mis-cancer-news-102/flight- attendants-show-higher-cancer-risks-735180.html
ESPN – June 25 Hall Of Famer Jim Kelly Hosts Youth Camp, Days After Another Surgery Hall of Fame quarterback Jim Kelly hosted his 31st annual youth football camp at the Buffalo Bills’ New Era Field on Monday, three days after being released from the hospital following another oral surgery. Last week, Mount Sinai West head and neck surgeon Mark Urken, MD, performed surgery to add tissue into the upper portion of Kelly’s mouth following a recurrence of his cancer. Kelly had surgery back in March to remove the cancer and reconstruct his jaw. He is scheduled to have permanent dentures inserted during a follow-up procedure in September. - Mark L. Urken, MD, Professor, Otolaryngology, Icahn School of Medicine at Mount Sinai, Head and Neck Surgeon, Mount Sinai West Learn more: http://www.espn.com/nfl/story/_/id/23908067/buffalo-bills-great-jim-kelly-youth-camp- following-surgery Additional coverage: Yahoo Sports https://sports.yahoo.com/m/c902cf01-5c00-3cbf-9674-e4b8494f075e/kelly-hosts-youth-camp- days.html
Metro NY – June 26 Ask Mount Sinai: Protect Yourself From Ticks This Summer—Sheila Dougherty Most people know ticks are carriers of Lyme disease, and that if you have a pet, a monthly preventive is a must. Alexandra Abrams-Downey, MD, assistant professor of medicine and infectious diseases at the Icahn School of Medicine at Mount Sinai, talks about having a safe and tick-free summer. “If you find a tick, it’s important to remove it quickly. Using a tweezers, grasp the rick as close to the skin’s surface as possible and pull gently in a steady, upward motion. After removing the tick, clean the area with soap or water. Never use petroleum jelly, nail polish, kerosene or matches to remove a tick,” said Dr. Abrams- Downey. - Alexandra Abrams-Downey, MD, Assistant Professor, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: https://www.metro.us/body-and-mind/ask-mount-sinai-protect-yourself-ticks-summer
My Jewish Learning: Here Now – June 26 How To Help A Friend Who Is Struggling With Their Mental Health It can be challenging to know the best way to support someone who is struggling with mental health issues, but now more than ever, your friendship is needed. “As a friend, you are usually the first person to see that something is wrong and to say something,” said Kashmira Rustomji, MD, assistant professor of pediatrics, adolescent medicine and psychiatry at the Icahn School of Medicine at Mount Sinai and an adolescent psychiatrist at the Mount Sinai Adolescent Health Center. “Not everyone feels comfortable discussing mental health, but even if your friend doesn’t come flat out and say there is a problem, you may pick up on some clues yourself,” said Dr. Rustomji. - Kashmira Rustomji, MD, Assistant Professor, Pediatrics, Adolescent Medicine, Psychiatry, Icahn School of Medicine at Mount Sinai Learn more: https://www.myjewishlearning.com/here-now/how-to-help-a-friend-who-is-struggling-with- their-mental-health/
Reader’s Digest – June 26 What the Color Of Your Bruise Is Trying To Tell You— Ashley Lewis A bruise typically appears hours after you injure the tissues just below the skin’s surface, whether it’s from hitting your knee on the coffee table or falling down the stairs. As your red blood cells start to break down, your bruise will progress into a deep purple or blue color. “Macrophages, the white blood cells, start to break down those red blood cells,” said Hooman Khorasani, MD, assistant clinical professor of dermatology and chief of the division of dermatologic and cosmetic surgery at the Icahn School of Medicine at Mount Sinai. “They do the demolition.” The purple hues are a result of your blood cells rapidly losing oxygen as the cells leak into the tissues, which gives your blood a blueish hue. - Hooman Khorasani, MD, Assistant Clinical Professor, Dermatology, Chief, Division of Dermatologic and Cosmetic Surgery, Icahn School of Medicine at Mount Sinai Learn more: https://www.rd.com/health/wellness/what-the-color-of-your-bruise-is-trying-to-tell-you/
Crain’s Health Pulse – June 27 Health Home To Reward Patients For Taking Their Meds — Jonathan LaMantia Manhattan-based nonprofit Coordinated Behavioral Care (CBC) will use a health incentive program developed by startup Wellth to encourage medication compliance in patients who have recently left a psychiatric hospital. Wellth's app delivers reminders to patients to take their drugs daily, offering $30 a month to CBC participants if they adhere to their doctor's orders. Users are prompted to take a photo of each pill taken, and $2 are deducted for each missed day. Wellth's clients include Mount Sinai Health System. It has previously promoted medication adherence for conditions such as diabetes and heart failure. - Mount Sinai Health System Learn more: http://www.crainsnewyork.com/article/20180627/PULSE/180629924/new-website-focuses-on- cancer-information (Subscription required)
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 28, 2018 Date: Thursday, June 28, 2018 2:49:59 PM Attachments: ATT00001.txt
In the News June 28, 2018
Queens Gazette – June 27 Mount Sinai Queens Celebrates 19 Years; Recognizes Outstanding Hospital Staff, FDNY-EMS Mount Sinai Queens held a hospital-wide celebration on June 21 to mark its 19th anniversary of delivering high-quality health care in Queens. The festivities included awards for outstanding staff and clinicians, and FDNY-EMS Paramedics and Emergency Medical Technicians. “Since the opening of the Mount Sinai Queens Pavilion, we have experienced significant growth,” said Caryn A. Schwab, executive director of Mount Sinai Queens. “To support that growth, we have continued to expand physician faculty, RNs, technicians, and staff. We are proud to have such a strong team of caring and engaged employees.” David L. Reich, MD, president and chief operating officer of the Mount Sinai Hospital said, “Mount Sinai Queens is an outstanding model of proactive health care, a hospital dedicated to keeping the community healthy through superb outpatient services, and, when needed, excellent inpatient care.” - Caryn A. Schwab, Executive Director, Mount Sinai Queens - Judy Trilivas, Chief Operating Officer, Mount Sinai Queens - David L. Reich, MD, President, Chief Operating Officer, The Mount Sinai Hospital Learn more: http://www.qgazette.com/news/2018-06-27/Front_Page/MSQ_Celebrates_19_Years.html
Fierce Healthcare – June 27 Mount Sinai Finds Improved Outcomes, Patient Experience In ‘Hospital At Home’ Model — Paige Minemyer A "hospital at home" model can improve outcomes while also making for a better patient experience, according to a new study. Researchers at the Mount Sinai Health System followed about 500 patients from November 2014 to August 2017, with more than half receiving in the home hospital model while the rest were given traditional inpatient care. Patients in the hospital at home program had an 8.6 percent readmission rate compared to the 15.6 percent for the control group, and a 3.2-day average length of stay compared to 5.5 days. The study also found that these patients were less likely to visit the emergency department and were significantly less likely to require a transfer to a skilled nursing facility for post- acute care. Albert Siu, MD, MSPH, chair emeritus of the department of geriatrics and palliative medicine at the Icahn School of Medicine at Mount Sinai, one of the study’s authors, said that thought the program can’t offer every inpatient service at home, the results are proof that the model could be a safe alternative for many patients. - Albert Siu, MD, MSPH, Chair Emeritus, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.fiercehealthcare.com/hospitals-health-systems/mount-sinai-finds-improved- outcomes-patient-experience-hospital-at-home Additional coverage: Becker’s Hospital Review https://www.beckershospitalreview.com/quality/hospital-at-home-beats- inpatient-care-in-readmission-rates-patient-experience.html
Wired – June 27 These Beating Mini-Hearts Could Save Big Bucks, And Maybe Lives —Megan Molteni The idea of using tiny, artificial organs to test drugs isn’t new. But getting the biology to actually work is a recent development. Novoheart’s Hong Kong headquarters houses a dozen pea-shaped, pulsating blobs. They’re 3D human heart ogranoids – a simplified shrunken-down version of the real thing – the first ever to contain a hollow chamber, like one of the four that’s beating inside the human chest. And they’re the future of drug testing. When Kevin Costa, PhD, associate professor of medicine, cardiology, director of cardiovascular cell and tissue engineering at the Icahn School of Medicine at Mount Sinai, and co-founder of Novoheart, first started working on mini-hearts, scientists could only grow cells in single layer on a dish. Dr. Costa says the 3-D tissues are still more like baby hearts than adult hearts, but they respond more realistically than the strip-shaped version. - Kevin Costa, PhD, Associate Professor, Medicine, Cardiology, Director, Cardiovascular Cell and Tissue Engineering, Icahn School of Medicine at Mount Sinai Learn more: https://www.wired.com/story/these-beating-mini-hearts-could-save-big-bucksand-maybe- lives/
American Council On Science and Health – June 27 Could Herpes Cause Alzheimer’s? Maybe— Josh Bloom A recent study in the journal Neuron has found a strong link between two rather obscure and poorly understood families of herpesviruses that infect humans and Alzheimer’s disease. This is a fascinating development. Joel Dudley, PhD, director of the Next Generation Health Care Institute at the Icahn School of Medicine at Mount Sinai and executive vice president on precision health for the Mount Sinai Health System, and colleagues identified two herpes viruses that were strongly associated with AD. The group found that people who had AD when they were alive has more of two viruses, in their brains than those who did not. “This research offers strong support for a long-controversial hypothesis that viruses might be involved in the development of Alzheimers disease. We didn’t have a horse in this virus race whatsoever. It’s the data that took us there. And now, not only is the viral hypothesis resurrected: it has specific testable pathways and networks and interactions that can be explored and reconciled with the rest of the work emerging in Alzheimers,” he said. - Joel Dudley, PhD, Director, Next Generation Healthcare Institute, Associate Professor, Genetics and Genomic Sciences, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Executive Vice President, Precision Health, Mount Sinai Health System - Samuel Gandy, MD, PhD, Professor, Neurology, Psychiatry, Associate Director, Alzheimer’s Disease Research Center, Icahn School of Medicine at Mount Sinai, Director, The Mount Sinai Center for Cognitive Health and NFL Neurological Care - Benjamin P. Readhead, Icahn Institute for Multiscale Biology, Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai Learn more: https://www.acsh.org/news/2018/06/25/herpes-linked-autism-it-plausible-13118
AJMC News – June 27 Study Uses Nasal Brush Test To Identify Biomarker of Asthma— Alison Rodriguez Asthma is a common disease that affects people of all ages; however, it remains underdiagnosed. Researchers have recently identified a genetic biomarker of asthma that can be tested for using a nasal brush and basic follow-up data analysis. A study in Scientific Reports applied machine learning algorithms to the genetic RNA data retrieved from nasal brushes of patients with and without asthma. “Mild to moderate asthma can be difficult to diagnose because symptoms change over time and can be complicated by other respiratory conditions,” said senior author, Supinda Bunyavanich, MD, MPH, associate professor of genetics and genomic sciences, and pediatrics at the Icahn School of Medicine at Mount Sinai. “Our nasal brush test takes seconds to collect. For time-strapped clinicians, particularly primary care providers at the front lines of asthma diagnosis, this could greatly improve patient outcomes through early and accurate diagnosis.” - Supinda Bunyavanich, MD, MPH, Associate Professor, Genetics and Genomic Sciences, Pediatrics, Icahn School of Medicine at Mount Sinai - Gaurav Pandey, PhD, Assistant Professor, Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai Learn more: https://www.ajmc.com/newsroom/study-uses-nasal-brush-test-to-identify-biomarker-of- asthma
Associated Press – June 28 Migrating birds create flu bonanza for scientists to study – Kathy Young Huge flocks of famished birds scour the sands of Delaware Bay for the tiny greenish eggs an army of horseshoe crabs lays every spring. It’s a marvel of ecology as shorebirds migrating from South America to the Arctic time a stop critical to their survival to this mass crab spawning. It’s also one of the world’s hot spots for bird flu — a bonanza for scientists seeking clues about how influenza evolves so they just might better protect people. Experts like Adolfo Garcia-Sastre, director of the Global Health and Emerging Pathogens Institute and professor of microbiology, medicine and infectious diseases at the Icahn School of Medicine at Mount Sinai, say it’s important to know how flu changes in nature. “Now this virus, in general, stay in birds,” said Dr. Garcia-Sastre. “But from time to time, some of these birds may jump into a different host.” - Adolfo Garcia-Sastre, PhD, Director, Global Health and Emerging Pathogens Institute, Professor, Microbiology, Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai Learn more: https://apnews.com/0581a86b452d46148408c7ef843fc482/Migrating-birds-create-flu-bonanza- for-scientists-to-study
Healio: Cardiology Today – June 27 Balloon-Expandable TAVR System Safe In Very Large Annuli — Dave Quaile Transcatheter aortic valve replacement with a 29-mm balloon-expandable valve beyond manufacturer- recommended range is safe and conferred acceptable rates of paravalvular leak in patients with extremely large annuli, according to results published in JACC: Cardiovascular Interventions. “TAVR in extremely large annuli has been previously reported in small case series, but larger experience has not been described,” wrote Gilbert H. Tang, MD, senior faculty of cardiovascular surgery at the Icahn School of Medicine at Mount Sinai, surgical director of the Structural Heart Program at the Mount Sinai Health System, and colleagues in the study background. “Longer follow-up will determine valve durability and postprocedural [multidetector] CT will help identify potential mechanisms of [paravalvular leak] in patients with extremely large annuli who undergo [Sapien 3] TAVR.” - Gilbert H. Tang, MD, Senior Faculty, Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai, Surgical Director, The Structural Heart Program, Mount Sinai Health System Learn more: https://www.healio.com/cardiac-vascular-intervention/transcatheter-aortic-valve- replacement/news/online/%7Bdc902650-16c8-4097-a540-88ee0f2eb6b1%7D/balloon-expandable-tavr- system-safe-in-very-large-annuli
Nature Biotechnology – June 27 Everything But Amyloid: New Thinking Prompts FDA Revamp — Eva von Schaper In the midst of another round of grim news for Alzheimer’s disease (AD) drug developers, the US Food and Drug Administration issued a draft guidance aimed at helping industry enroll patients in studies using biomarkers, with a clear shift towards earlier stages of the disease. “The bottom line is that the pathology and biomarker changes begin in the 40s but the symptoms do not begin until the 70s or 80s,” said Samuel Gandy, MD, PhD, professor of neurology, psychiatry, and associate director of the Alzheimer’s Disease Research Center at the Icahn School of Medicine at Mount Sinai. “We will only win by discovering cures that are useful as measured by midlife biomarkers. Sadly, once there are symptoms, we are too late. The new guidance recognizes this fact and endorses for drug development for the first time,” he added. - Samuel Gandy, MD, PhD, Professor, Neurology, Psychiatry, Associate Director, Alzheimer’s Disease Research Center, Icahn School of Medicine at Mount Sinai, Director, The Mount Sinai Center for Cognitive Health and NFL Neurological Care Learn more: No web link available.
The Philadelphia Inquirer – June 27 The Era Of Circadian Lighting In Health Care Is Dawning— Stacey Burling Mariana Figueiro, director of the Lighting Research Center at Rensselaer Polytechnic Institute, worked with the Mount Sinai Hospital to improve lighting for stem-cell transplant patients. The intervention had “very positive effects” on depression, fatigue, and sleep quality. William H. Redd, PhD, professor of oncological sciences at the Icahn School of Medicine at Mount Sinai, who is involved in that light research, worries that enthusiasm for circadian lighting may have gotten ahead of the science but is himself enthusiastic. “I personally believe that this has gigantic potential,” he said. The stem-cell unit is a good place to test light, he said, because patients are there at least two weeks. - William H. Redd, PhD, Professor, Oncological Sciences, Icahn School of Medicine at Mount Sinai Learn more: http://www.philly.com/philly/health/the-era-of-circadian-lighting-in-health-care-is- dawning-20180627.html
Medscape – June 28 Finding Fascination In Medicine Again— Gregory B. Dodell, MD Research on mindfulness has demonstrated clinical improvement in a wide range of medical conditions, including chronic pain, diabetes, anxiety, and sleep disorders. Most people have heard of mindfulness at this point, and there's a reason why it has become trendy – it works. Gregory Dodell, MD, assistant clinical professor of medicine, endocrinology, diabetes and bone disease at the Icahn School of Medicine at Mount Sinai writes, “As physicians, we spend our days taking care of other people; perhaps we were built this way. Carving out this time for yourself has re-invigorated me. Ironically, I think that caring for myself has made me a better doctor, husband, father and friend.” - Gregory B. Dodell, MD, Assistant Clinical Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: https://www.medscape.com/viewarticle/898550
MedPage Today – June 27 Are Estimates Of Aspirin’s Bleeding Risk Off The Mark? — Nicole Lou Major bleeding may be more common than previously thought among people without cardiovascular disease (CVD) who are not on antiplatelets, a prospective cohort study suggested. The role of aspirin in primary prevention of cardiovascular disease remains uncertain, and the current study adds to this uncertainty by showing higher than previously assumed bleeding rates," commented Roxana Mehran, MD, professor of medicine, cardiology, population health science and policy, and director of interventional cardiovascular research and clinical trials at the Zena and Michael A. Weiner Cardiovascular Institute at the Icahn School of Medicine at Mount Sinai, who was not involved in the analysis. And even though this data may not be directly applicable to interventional cardiology trials, what the study does is it highlights the importance of accurately determining bleeding rates, she added. - Roxana Mehran, MD, Professor, Medicine, Cardiology, Population Health Science and Policy, Director, Interventional Cardiovascular Research and Clinical Trials, Zena and Michael A. Weiner Cardiovascular Institute, Icahn School of Medicine at Mount Sinai Learn more: https://www.medpagetoday.com/cardiology/prevention/73733
Cure Today – June 27 Despite Skills Training, Goals Of Care Discussions Are Still Not Always Happening — Kristie L. Kahl Goals of care discussions between patients and their oncologists are very important. However, the prevalence of and satisfaction with these discussions are somewhat lagging, according to study results presented at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting. “It is really important for patients to understand goals of care discussions because that is the way they will be able to make informed decisions about subsequent treatment that can affect key parts of their lives,” said Nina Bickell, MD, professor of population health science and policy, medicine and general internal medicine at the Icahn School of Medicine at Mount Sinai. Therefore, Dr. Bickell and colleagues set out to determine if communication skills coaching had an impact on the prevalence and satisfaction with goals of care discussions among patients with advanced cancers. - Nina A. Bickell, MD, Professor, Population Health Science and Policy, Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.curetoday.com/articles/despite-skills-training-goals-of-care-discussions-are- still-not-always-happening
TIME Magazine – June 27 What’s The Best Way To Treat Plantar Fascitis? — Markham Heid Often described as a throbbing pain that strikes the meat of the heel and radiates outward, plantar fasciitis is one of the most common foot conditions in the US. Roughly two million Americans suffer from it, and it can last anywhere from a few weeks to several months at a stretch. Running can cause microscopic tears in the plantar fascia. If those tears aren’t given enough time to heal, they can become painful, said James Gladstone, MD, associate professor of orthopedics and sports medicine at the Icahn School of Medicine at Mount Sinai and co-chief of sports medicine at The Mount Sinai Hospital. Dr. Gladstone said the foot’s connective tissues and muscles are in a constant state of breakdown and regeneration – processes that are unusually in equilibrium. “But if you’re over-training, your body isn’t able to maintain the build-up part, and so you start breaking down and getting all these overuse injuries like plantar fasciitis,” he said. - James Gladstone, MD, Associate Professor, Orthopedics, Sports Medicine, Icahn School of Medicine at Mount Sinai, Co-Chief, Sports Medicine, The Mount Sinai Hospital Learn more: http://time.com/5322861/plantar-fasciitis-treatment/
Shape Magazine – June 27 FDA Approves CBD-Based Drug To Treat Seizures— Macaela Mackenzie Derived from CBD oil, a drug called Epidiolex was just approved to treat seizures in children and adults with two rare but severe forms of epilepsy, both of which typically develop in childhood. Considering the fact that marijuana is still illegal in many states across the U.S., the FDA approval is significant; it marks the first marijuana-based drug to be approved in the country. But even though the medicinal oil has long been used as an at-home alternative therapy for seizures, neurologists admit that they still aren't quite sure how CBD oil works. "There are several different mechanisms we're exploring right now," said Steven Wolf, MD, associate professor of neurology and pediatrics at the Icahn School of Medicine at Mount Sinai, director of pediatric epilepsy unit and director of pediatric neurology at Mount Sinai St. Luke’s and Mount Sinai West. Every anti-epileptic drug's job is to stabilize the nerves from over-firing," said Dr. Wolf. "Each drug that the FDA has approved for seizures works on some aspect of preventing that neuron from firing away like crazy." Based on what neurologists know about epilepsy, for this new drug Epidiolex to accomplish that, CBD likely triggers a reaction in the brain that either blocks certain neurotransmissions or stabilizes neurons, he said. - Steven Wolf, MD, Associate Professor, Neurology, Pediatrics, Icahn School of Medicine at Mount Sinai, Director, Pediatric Epilepsy, Co-Director, Epilepsy Unit, Mount Sinai Beth Israel, Director, Pediatric Neurology, Mount Sinai St. Luke’s-Mount Sinai West, Co-Director, Tuberous Sclerosis Clinic Learn more: https://www.shape.com/lifestyle/mind-and-body/fda-approves-cbd-based-drug-treat- seizures
Survivor Net – June 27 Does Smoking Cause Lung Cancer? We all know that smoking poses a major risk for lung cancer. But there are other lifestyle choices which can reduce your risk of developing cancer or having it come back. “As someone on the front lines, who sees this every day, I’ve seen lung cancer caused by marijuana that is incredibly aggressive,” said Raja Flores, MD, chairman of the department of thoracic surgery for the Mount Sinai Health System. “There is no real good population-based study that looks at marijuana smoking and that has had enough time elapsed to show its associated with lung cancer, but I’ve seen it. I’ve seen multiple, multiple cases of it. I see it every day,” Dr. Flores added. - Raja Flores, MD, Steven and Ann Ames Professorship in Thoracic Surgery, Director, Thoracic Surgical Oncology Program, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, System Chair, Thoracic Surgery, Mount Sinai Health System Learn more: https://www.survivornet.com/articles/smoking-marijuana-may-cause-lung-cancer/ Additional coverage: https://www.survivornet.com/articles/beware-marketing-gimmicks-robotic-thoracic-surgery/ https://www.survivornet.com/articles/considering-palliative-care/ https://www.survivornet.com/articles/treatment-for-stage-iv-lung-cancer/ https://www.survivornet.com/articles/digesting-your-lung-cancer-diagnosis/ https://www.survivornet.com/articles/questions-to-ask-when-choosing-a-surgeon/
Survivor Net – June 27 Recovering From A Lumpectomy Not every breast cancer patient has to undergo a full mastectomy in order to rid their body of cancer. For many patients, a lumpectomy and radiation is also an option. The surgery typically takes about an hour and is an outpatient procedure–meaning a patient will be able to go home the same day. “It’s abnormal to have a lot of pain after a lumpectomy,” said Sarah Cate, MD, director of special surveillance and breast program at the Mount Sinai Chelsea Center. For early stage breast cancer, studies have shown that lumpectomy plus radiation is as effective a treatment in preventing a recurrence of breast cancer as mastectomy. - Sarah P. Cate, MD, Director, Special Surveillance and Breast Program, Mount Sinai Downtown- Chelsea Center Learn more: https://www.survivornet.com/articles/recovering-from-a-lumpectomy/ Additional coverage: https://www.survivornet.com/articles/lumpectomy-or-mastectomy/ https://www.survivornet.com/articles/oncoplastic-surgery/
Survivor Net – June 27 Treating Early-Stage Colon Cancer The type of colon surgery that is performed is dependent on the location of the tumor within the colon. If the tumor is located on the right side of the colon, also known as the ascending colon, then a right colectomy is performed. For tumors located in the descending colon, a left colectomy is performed. “A subtotal colectomy is required in certain cases, which is when the majority of the colon is removed and the rectum is left behind. This may have a greater impact on bowel function after surgery. However, many patients are able to adapt to the loss of this amount of colon,” said Daniel M. Labow, MD, professor of surgery, chief of surgical oncology at the Icahn School of Medicine at Mount Sinai and site chair of the department of surgery at Mount Sinai St. Luke’s and Mount Sinai West. - Daniel M. Labow, MD, Professor, Surgery, Chief, Surgical Oncology, Hepatobiliary Surgery, Icahn School of Medicine at Mount Sinai, Site Chair, Department of Surgery, Mount Sinai St. Luke’s, Mount Sinai West Learn more: https://www.survivornet.com/articles/different-operations-for-different-cancers/ Additional coverage: https://www.survivornet.com/articles/stage-3-colon-cancer/ https://www.survivornet.com/articles/hyperthermic-intraperitoneal-chemotherapy-for-colon-cancer/ https://www.survivornet.com/articles/stage-iv-colon-cancer/ https://www.survivornet.com/articles/the-benefits-of-robotic-surgery/ https://www.survivornet.com/articles/what-is-a-colostomy/
Spine Universe – June 27 Optimal End Level For Long-Segment Cervical Fusion To The Thoracic Spine? — Kristin Della Volpe Extending posterior cervical fusions for degenerative spine conditions into the thoracic spine is associated with less risk for pseudarthrosis but significantly greater blood loss and a tendency toward greater operating room time and length of hospital stay, according to a multicenter retrospective analysis published in The Spine Journal. “This is an important topic with a paucity of high level scientific evidence available for decision making. Much like the debate of stopping a fusion at the lower lumbar spine version extending a fusion into the sacrum, there are pros and cons to each approach,” said Saad B. Chaudhary, MD, MBA, associate director of the spine surgery fellowship at the Icahn School of Medicine at Mount Sinai. - Saad B. Chaudhary, MD, MBA, Minimally Invasive & Complex Spine Surgery, The Mount Sinai Hospital, Associate Director, Spine Surgery Fellowship, Assistant Professor, Department of Orthopedic Surgery, Icahn School of Medicine at Mount Sinai Learn more: https://www.spineuniverse.com/professional/news/optimal-end-level-long-segment- cervical-fusion-thoracic-spine
Healthline – June 27 Kelly Clarkson Used This Plant-Based Diet To Get Healthy — Kimberly Holland Kelly Clarkson has dropped 37 pounds in the last year. She gives credit for her waist-shrinking success to a new, clean eating plan: the Plant Paradox diet. The Plant Paradox, claims the lectins – proteins present in many foods – are responsible for a variety of health ailments, from weight gain and leaky gut to inflammation and thyroid issues. Eliminating lectins in your diet can reverse these complications. “Lectins are known as pro-inflammatory and autoimmunity-triggering proteins,” said Luiza Petre, MD, assistant clinical professor of medicine and cardiology at the Icahn School of Medicine at Mount Sinai. “Once they enter the bloodstream, they trigger an autoimmune response. They can also directly irritate the intestinal lining, leading to leaky gut syndrome, or the condition where our gut is not working as an effective filter anymore.” - Luiza Petre, MD, Assistant Clinical Professor, Medicine, Cardiology, Icahn School of Medicine at Mount Sinai Learn more: https://www.healthline.com/health-news/kelly-clarkson-diet
Furthermore – June 27 Three Lesser-Known Sources Of Antioxidants— Jessica Migala Kale, spinach, and blueberries all contain antioxidants, compounds that fight damaging free radicals in the body, improve post-exercise recovery, and lower the risk of disease. But here's why you should opt for these foods as well. The red-orange color of this rainbow trout’s flesh indicates the presence of an antioxidant called astaxanthin. It has the eye health benefits of carotenoids and similar anti-inflammatory properties as antioxidants, said Kelly Hogan, MS, RD, CDN, clinical nutrition and wellness manager at the Dubin Breast Center at The Mount Sinai Hospital. Rye, oats, and millet add important phytochemicals like lignans and flavonoids that may protect against certain cancers. - Kelly Hogan, MS, RD, CDN, Clinical Nutrition and Wellness Manager, The Dubin Breast Center, The Mount Sinai Hospital Learn more: https://furthermore.equinox.com/articles/2018/06/hidden-antioxidants
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 From: ITNDaily Subject: Mount Sinai In The News - June 29, 2018 Date: Friday, June 29, 2018 12:19:53 PM Attachments: ATT00001.txt
In the News June 29, 2018
Quartz – June 29 To Help Poor Americans Live Longer, Doctors Are Copying Rwanda, Ethiopia and Brazil – Annalisa Merelli Despite spending more money per capita on healthcare than any other country, the United States still struggles with dramatic health inequality. So to raise life expectancy in very poor areas like Oglala Lakota County in South Dakota, some researchers are looking at developing countries for advice: At Mount Sinai Health System, a research group from the Icahn School of Medicine at Mount Sinai is studying countries like Rwanda, which has added more than 30 years to citizens’ average life expectancy since 1990. “People systematically don’t look at low- and middle-income countries” as models of public health policy, acknowledges Prabhjot Singh, MD, PhD, director of the Arnhold Institute for Global Health and chair of the school’s Task Force for Global Advantage. “But not every poor country has been able to make the same breakthrough.” This, he said, suggests that some developing nations’ public health strategy plays an important and teachable role. The Mount Sinai task force, which published its first findings in April, looked at outstanding national health improvements in Rwanda, Ethiopia, and Brazil. It found a common thread: Community involvement. - Prabhjot Singh, MD, PhD, Director, Arnhold Institute for Global Health, Chair, Department of Health System Design and Global Health, Icahn School of Medicine at Mount Sinai Learn more: https://qz.com/1296206/us-life-expectancy-could-benefit-from-the-lessons-of-developing- countries-say-mount-sinai-researchers/ Additional coverage: Global Advisors http://www.globaladvisors.biz/blog/2018/06/29/to-help-poor-americans-live-longer- doctors-are-copying-rwanda-ethiopia-and-brazil/
The New York Times – June 29 Live, From The Children’s Hospital — Andy Newman Most children’s hospitals have child life departments. The one at Kravis Children’s Hospital at Mount Sinai, the 70-bed hospital overlooking Central Park, has a full-time staff of 20 (plus two therapy dogs) and offers art, creative writing and meditation among other therapies. Much of the department’s work is aimed at normalizing life for patients who cannot leave their room. To this end, it operates a television station, KidZoneTV that broadcasts live interactive shows three times a day. For patients well enough to visit it, KidZoneTV studio can be a place of transformation. Helping sick children have fun is a demanding job. “Sometimes we have very difficult runs where we have a death or two a week,” said Diane Rode, MPS, director of the child life and creative arts therapy department at the Kravis Children’s Hospital at Mount Sinai. “The potential for absorption of secondary trauma is high.” The child life workers meet regularly for reflective practice, where they process the emotions that come up when, for example, you forge a connection to a patient who does not recover. - Diane C. Rode, MPS, Assistant Professor, Pediatrics, Child Life, Icahn School of Medicine at Mount Sinai, Director, Child Life and Creative Arts Therapy Department, Kravis Children’s Hospital at Mount Sinai Learn more: https://www.nytimes.com/2018/06/29/nyregion/childrens-hospital-tv-station.html
Cardiovascular Business – June 28 3D Mini-Hearts Could Aid First-Line Testing For Drugs — Daniel Allar A company called Novoheart has created the first 3D heart organoid—a miniature version of the real thing—which contains a hollow chamber similar to one of the four in a normal human heart. According to Novoheart’s cofounder, Kevin Costa, PhD, associate professor of medicine, cardiology and director of cardiovascular cell and tissue engineering at the Icahn School of Medicine at Mount Sinai, the hollow organoids behave more like a heart than flat patches of cardiac tissue. “We don’t fully understand why the hollow sphere responds more like the real thing,” he said. “Is it something about fluid slushing around inside it? Do shear stresses impact cell development? It’s not clear to us yet, but there’s definitely something unique about being in that shape. It acts like a heart, so it is a heart.” Dr. Costa said Novoheart’s 3D organoids are actually more like a baby heart than an adult heart, but pharmaceutical companies are still interested in the drug-testing capabilities of this and other bioengineered human heart tissue technologies. - Kevin Costa, PhD, Associate Professor, Medicine, Cardiology, Director, Cardiovascular Cell and Tissue Engineering, Icahn School of Medicine at Mount Sinai Learn more: https://www.cardiovascularbusiness.com/topics/healthcare-economics/3d-mini-hearts-aid- testing-drugs
News Medical & Life Sciences – June 29 Mount Sinai Study Could Help Doctors Better Understand and Manage Diseases Affecting The Larynx In a first-of-its kind study, Mount Sinai researchers have used sensory mapping to discover that the posterior part of the larynx is the main area of the voice box to protect the airway from potentially dangerous swallowed or inhaled substances. This novel finding can potentially help doctors better understand and manage diseases affecting the larynx and lead to new, targeted treatments. The results of this study have been published in the June online edition of The Laryngoscope. "The human voice box ('larynx') is arguably one of the most life-sustaining organs in the body, yet there is still much we don't know about its basic functions. This study sheds light on a critical protective function of the larynx that we have not had definite proof of until now," explained author Catherine Sinclair, MD, assistant professor of otolaryngology at the Icahn School of Medicine at Mount Sinai. "Understanding this aspect of basic larynx physiology is essential to help us diagnose laryngeal disease, manage it appropriately, and create new therapies." - Catherine Sinclair, MD, Assistant Professor, Otolaryngology, Icahn School of Medicine at Mount Sinai, Director, Division of Head and Neck Surgery, Mount Sinai West - Sedat Ulkatan, MD, Director, Intraoperative Neurophysiology, Mount Sinai West - Maria Tellez, MD, Neurophysiologist, Mount Sinai West Learn more: https://www.news-medical.net/news/20180629/Mount-Sinai-study-could-help-doctors-to- better-understand-and-manage-diseases-affecting-the-larynx.aspx
Drug Target Review – June 29 Computational Models Provides Genetic Insight into Atherosclerosis Researchers have identified a new gene-activation pathway caused by lipids associated with coronary artery disease, a finding that could help identify new directions in research and drug development. The discovery that exposure to lipids activates a gene called MTHFD2 in the walls of blood vessels was made by researchers from the Institute for Cardiovascular Physiology of Geothe University and the Department of Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai. The researchers used a computational model of the cells lining blood vessels in the human heart developed at Mount Sinai. “Endothelial cell response to lipids has been studied extensively over the years, but it was still unknown that MTHFD2 was even functional in these cells,” said Jun Zhu, PhD, professor of genetics and genomic sciences at the Icahn School of Medicine at Mount Sinai, and head of data science at Sema4, and co-senior author of the study. “Computational biological models such as the one we used in this study are allowing us to uncover a wealth of knowledge about complex diseases that we never could before.” - Jun Zhu, PhD, Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, Head, Data Science, Sema4 Learn more: https://www.drugtargetreview.com/news/32766/computational-models-atherosclerosis/ Additional coverage: Medical Xpress https://medicalxpress.com/news/2018-06-genetic-insights-atherosclerosis.html Science Codex http://www.sciencecodex.com/computational-models-provide-novel-genetic-insights- atherosclerosis-621606 MedIndia https://www.medindia.net/news/fatty-acids-activates-gene-that-causes-atherosclerosis-180598- 1.htm Dotemirates https://www.dotemirates.com/en/details/1298601430?from=dot
PHYS.org – June 28 Researchers Identify Mesenchymal Stem Cells in Human Arteries Researchers have identified, in situ and in vivo, adventitial CD90+ and mesenchymal stem cells in human arteries for the first time. This is the first paper to show the existence of those cells in adult human vessels and provide a clear link of these cells to vascular disease. "The next step is to delve more deeply into the biology of these cells, and to identify specific ways to manipulate these cells as a clinical therapeutic tool," said senior author Jason Kovacic, MD, PhD, associate professor of medicine at the Icahn School of Medicine at Mount Sinai. - Jason Kovacic, MD, PhD, Associate Professor, Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://phys.org/wire-news/291643175/researchers-identify-mesenchymal-stem-cells-mscs- in-human-arteri.html
CBS Newswire – June 29 New Device Is Changing the Way Doctors Perform Cataract Surgery Helen Polynsky loves the theater, but then shows started getting a little blurry. She needed surgery for cataracts, a clouding of the lens of the eyes which can affect vision. Most are related to aging. Her doctor, Kira Manusis, MD, assistant professor of ophthalmology at the Icahn School of Medicine at Mount Sinai and ophthalmologist at the New York Eye and Ear Infirmary of Mount Sinai used a new handheld device called the miLoop to treat her right eye. “Generally we take out the cataract and break it up in the eye using either ultrasound energy, laser energy, and both of those modalities deliver energy into the eye. Miloop can do the same thing, but without delivering that energy,” said Dr. Manusis. No energy to the eye means less swelling and inflammation. Dr. Manusis said the new technology allows patients to recover faster. - Kira Manusis, MD, Assistant Professor, Ophthalmology, Icahn School of Medicine at Mount Sinai Learn more: https://wreg.com/2018/06/29/new-device-is-changing-the-way-doctors-perform-cataract- surgery/
CNN – June 18 FBI Official, Dead of 9/11 Related Cancer, Remembered As Number of Cases Grow — David Shortell and Nadia Kounang David LeValley, the FBI’s top agent in Atlanta, passed away in May of cancer brought on by his time as a first responder in the ruins of lower Manhattan after 9/11. As the World Trade Center towers collapsed, a dense toxic cloud of dust that included asbestos, cement, glass shards, and over 91,000 liters of jet fuel enveloped lower Manhattan. It is believed that 60,000 to 70,000 first responders breathed those toxins in during rescue and clean-up efforts. In the immediate aftermath of the attacks, doctors saw irritant-related responses. "Early on we picked up asthma, sinus problems, heartburn from breathing and swallowing the stuff," said Michael Crane, MD, MPH, director of the World Trade Center Health Program Clinical Center of Excellence at the Mount Sinai Hospital. According to the Centers for Disease Control and Prevention's World Trade Center Health Program, sinus issues, reflux and asthma are the three most common 9/11-related health issues among first responders and survivors of the attack. - Michael Crane, MD, MPH, Associate Professor, Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, Director, World Trade Center Health Program Clinical Center of Excellence, The Mount Sinai Hospital Learn more: https://www.cnn.com/2018/06/18/health/9-11-fbi-cancer/index.html
Healio: Cardiology Today – June 27 Evolocumab Reduces LDL, non-HDL in High-Risk Patients With Type 2 Diabetes—Katie Kalvaitis Treatment with the PCSK9 inhibitor evolocumab on top of maximally tolerated statin therapy resulted in significant reductions in LDL cholesterol and non-HDL cholesterol among patients with type 2 diabetes and hypercholesterolemia or mixed dyslipidemia enrolled in the BANTING study. The findings were reported at the American Diabetes Association Scientific Sessions. “These data are important, as they demonstrate that additional treatment options, such as Repatha, can help further reduce LDL and non- HDL in patients who are unable to reach targets with high-intensity statin therapy alone,” said Robert Rosenson, director of Cardiometabolic disorders at the Icahn School of Medicine at Mount Sinai. - Robert Rosenson, MD, Professor, Medicine, Cardiology, Director, Cardiometabolic Disorders, Icahn School of Medicine at Mount Sinai Learn more: https://www.healio.com/cardiology/diabetes/news/online/%7b35e84e78-8d42-48e1-90b4- 2732f03fee2f%7d/evolocumab-reduces-ldl-non-hdl-in-high-risk-patients-with-type-2-diabetes
MedPage Today – June 28 TAVR Can Work For XL Aortic Annulus— Nicole Lou Expanding the largest Sapien 3 (S3) transcatheter aortic valve replacement (TAVR) valve beyond the recommended range in patients with extra-large aortic annuli appeared safe in a multicenter report. Overexpansion of the device frame in 74 patients had 100 percent procedural success without annular rupture or coronary obstruction, reported a group led by Gilbert Tang, MD, senior faculty of cardiovascular surgery at the Icahn School of Medicine at Mount Sinai and surgical director of the Structural Heart Program for the Mount Sinai Health System, in JACC: Cardiovascular Interventions. - Gilbert H. Tang, MD, Senior Faculty, Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai, Surgical Director, The Structural Heart Program, Mount Sinai Health System Learn more: https://www.medpagetoday.com/cardiology/pci/73762
HealthPayer Intelligence – June 28 Can Retail Clinics Improve Patient Access, Reduce Costs For Payers? — Thomas Beaton Retail clinics are gaining in popularity among patients looking for quick, convenient care for minor ailments. Kiosks and no-appointment-needed offices located in corner pharmacies and big box stores have the potential to keep patients out of expensive emergency rooms or busy primary care providers. Retails clinics are sometimes confused with urgent care centers, but the two types of organizations provide different services. Mount Sinai Hospital said that an urgent care center usually operates 24/7 to offer services including x-rays, treat sprains and muscle strains, and provide treatment for nausea, vomiting, fevers, sinus problems, breathing problems, and the flu. - Mount Sinai Hospital Learn more: https://healthpayerintelligence.com/news/can-retail-clinics-improve-patient-access-reduce- costs-for-payers
The Daily Meal – June 28 Hanger Is Real, Science Confirms — Holly Van Hare Hanger, or extreme hunger that results in angry behavior, is attributed to low blood sugar. This drop in blood sugar can cause hypoglycemia if you go too long without eating a morsel. Deena Adimoolam, MD, assistant professor of medicine, endocrinology, diabetes and bone disease at the Icahn School of Medicine at Mount Sinai, said that your hormones are involved, too. When your blood sugar takes a dive, your levels of the stress hormone cortisol and adrenalines start to rise, making you feel on-edge. Another hormone, called neuropeptide Y, is also released when you’re hungry; this hormone is directly linked to aggression. - Deena Adimoolam, MD, Assistant Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai Learn more: https://www.thedailymeal.com/healthy-eating/hanger-real-science-confirms
Medical Daily – June 29 Five Ways to Relieve A Headache — Sadhana Bharanidharan Headaches can not only result in physical pain but also affect your ability to think and concentrate during the day. Mark Green, director of the Center for Headache and Pain Medicine at the Icahn School of Medicine at Mount Sinai recommended a relaxing shower to ease a headache. Make sure the temperature is hot or at least warm. “People who wake up with head pain- and that’s not rare – often try to stay in bed and pretend it’s not real, or hope that it will go away,” he said. Standing underneath hot water can reduce strain by loosening the muscles in the head, neck, and shoulder regions. - Mark W. Green, MD, Professor, Neurology, Anesthesiology, Perioperative and Pain Medicine, Director, The Center for Headache and Pain Medicine, Icahn School of Medicine at Mount Sinai Learn more: https://www.medicaldaily.com/5-ways-relieve-headache-425093
If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200