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In the News July 29, 2016

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In the News July 29, 2016 From: ITNDaily on behalf of Stephanie Sherman Subject: Mount Sinai In The News - July 29, 2016 Date: Friday, July 29, 2016 11:20:39 AM Attachments: ATT00002.txt In the News July 29, 2016 WBUR News – July 28 Doctors Need A New Skill Set For This Opioid Abuse Treatment — Karen Shakerdge Braeburn Pharmaceuticals, the company behind the newly FDA-approved treatment Probuphine, is teaching doctors how to use it. Although addiction specialists welcome Probuphine, which delivers a constant dose of the drug buprenorphine over six months, at this early stage it's complicated for physicians to add it to their repertoire. Patients using Probuphine were 14 percent more likely to stay opioid-free compared to those using a daily sublingual version of buprenophine, according to a study published this month in JAMA, the Journal of the American Medical Association. So it's good to have another way to deliver medication-assisted treatment, says Richard Rosenthal, medical director of addiction psychiatry for the Mount Sinai Health System. Rosenthal was one of two principal investigators on a Probuphine clinical trial. "Everybody is waking up to the fact that we're in the midst of an opioid epidemic," says Rosenthal. "There are actually very few medications for addiction of any kind. Given the addiction treatment system in the United States, most of the treatment that's given is psychosocial. There's very little use of FDA-approved medications." - Richard N. Rosenthal. MD, Professor, Psychiatry, Mount Sinai West Learn more: http://www.wbur.org/npr/487080738/doctors-need-a-new-skill-set-for-this-opioid-abuse- treatment MD Alert – July 28 Some Non-Celiac Gluten Sensitivity Patients May Have 'Celiac Lite' Disease — Marilynn Larkin A subset of patients with non-celiac gluten sensitivity (NCGS) may actually have a form of celiac disease, researchers in Spain report. A diagnosis of NCGS requires ruling out celiac disease on the basis of negative celiac serology and a duodenal biopsy of normal villi (no villous atrophy) in a person who is currently on a diet that contains gluten, but those diagnostic criteria may need to be revisited. Researchers conducted a small proof-of-concept study that aimed to demonstrate that gluten can trigger clinical symptoms in a subgroup of patients who currently fulfill the diagnostic criteria NCGS. Recent trials suggest that only a minority of those patients will exhibit symptoms in response to a gluten challenge. Commenting by email, Dr. Gina Sam, director of the Gastrointestinal Motility Center at The Mount Sinai Hospital in New York City said, "This study suggests that patients who do not have celiac disease but still have symptoms like a celiac patient (NCGS patients) do respond to a gluten-free diet. - Gina Sam, MD, MPH, Assistant Professor, Medicine, Gastroenterology, Icahn School of Medicine at Mount Sinai, Director, Gastrointestinal Motility Center, The Mount Sinai Hospital Learn more: http://www.mdalert.com/news/article/some-non-celiac-gluten-sensitivity-patients-may- have-celiac-lite-disease#sthash.TsRYUq2o.dpuf TDN – July 28 What Happens When You're Hypnotized? — Dennis Thompson Skeptics view hypnosis as a little-understood parlor trick, but a new study reveals real changes occur in the brain when a person enters a hypnotic state. Some parts of the brain relax during the trance while others become more active. Hypnosis was the first Western form of psychotherapy, but little is known about how it actually works. Experts selected 57 people for a study out of a pool of 545 potential participants. Thirty-six of the 57 displayed a high level of hypnotic susceptibility, while the other 21 did not appear to be very hypnotizable. Using MRI, researchers measured the subjects' brain activity by detecting changes in blood flow. This study provides "important evidence" that could help convince skeptical patients of hypnosis' potential benefits, said Guy Montgomery, PhD, associate professor of oncology, at the Icahn School of Medicine at Mount Sinai. However who specializes in integrative behavioral medicine. Montgomery added that it will take further research to make this specific knowledge directly useful in daily medicine. "How would I use this information to enhance procedures for patients?" he said. "I don't really know." - Guy H Montgomery, PhD, Oncology, Associate Professor, Director of the Integrative Behavioral Medicine Program, Icahn School of Medicine at Mount Sinai, The Mount Sinai Hospital Learn more: http://tdn.com/lifestyles/health-med-fit/what-happens-when-you-re- hypnotized/article_2e3da5d0-e793-5673-af47-4a642618e466.html The Guardian – July 28 Russian Olympic Team's Drug Usage Could Have Long Term Effects On Athletes' Health– Olga Oksman Further revelations in the Russian doping scandal have rocked the upcoming Olympic Games. Over 100 Russian athletes who would have competed in Rio have been barred due to an investigation into a state-run doping program that involved administering a cocktail of anabolic steroids to the country’s world-class athletes. Anabolic steroid use is nothing new when it comes to high-level athletes. The steroids found in Russia’s doping cocktail – nicknamed “The Duchess” by a Russian official – are often abused. Around 3%-5% of the population uses steroids, estimates Thomas Hildebrandt, assistant professor of psychiatry at the Icahn School of Medicine at Mount Sinai. While the muscle boosting effects of doping are well known, it is the mental effects, and what happens when someone finally stops using, that are often ignored. - Thomas Hildebrandt, PhD, Assistant Professor, Psychiatry, Icahn School of Medicine At Mount Sinai Learn more: https://www.theguardian.com/lifeandstyle/2016/jul/28/russian-olympic-rio-team-drug- steroids-health-effects Style Caster – July 28 Does Cold Water Actually ‘Shut’ Your Pores? — Lauren Caruso We’ve all been told approximately one million times that hot water opens your pores, and cold water, by the law of duality, shuts them. Bad news, though: We’ve been lied to—sort of. While pores aren’t exactly muscles themselves, “There are many tiny muscles in the skin attached to the hair follicles,” says Ellen Marmur, an associate clinical professor of dermatology, genetics, and genomic research at Icahn School of Medicine at Mount Sinai. “These piloerector muscles contract when cold— think goose bumps. Plus, all of the superficial muscles of the face are attached to the skin.” Plus, “Unless you’re following with moisturizer right away, splashing your face with any water will lead to evaporation and dryness of the outer layer of skin,” adds Heidi Waldorf, director of laser and cosmetic dermatology at The Mount Sinai Hospital. Looking for something more intense and long-lasting? If you’ve already walked down the road of chemical peels with little reward, both derms suggest Clear + Brilliant, an in-office laser treatment that uses similar wavelengths to Fraxel laser resurfacing but at lower energies, Dr. Waldorf says. And for now, don’t worry about ending your nightly face wash with a splash of cold water to the face—unless, of course, you’re just trying to keep yourself awake. - Heidi A Waldorf, MD, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai, Director Of Laser And Cosmetic Dermatology, The Mount Sinai Hospita, - Ellen S Marmur, MD, Assistant Professor, Dermatology, Icahn School of Medicine at Mount Sinai Learn more: http://stylecaster.com/beauty/does-cold-water-shut-pores/#ixzz4Fo4kznB5 Health Day – July 29 Is Non-Celiac Gluten Sensitivity Real? — Dennis Thompson Gluten sensitivity appears to be a real medical problem, and not a figment of the popular imagination conjured up by the gluten-free craze, a new study contends. Some people suffer changes within their bodies after eating gluten that are separate and distinct from those that accompany either celiac disease or wheat allergy, researchers report. Dr. Christina Tennyson is a gastroenterologist with The Mount Sinai Hospital. She called the new research "an exciting study as it will help further research of patients with non-celiac wheat sensitivity.” “This study demonstrates that there are objective markers of inflammation and cell damage seen in individuals with non-celiac wheat sensitivity. These mechanisms appear different than celiac disease," Tennyson added. "There have been no biomarkers available to diagnose non-celiac gluten sensitivity and this has made it difficult for doctors to accurately diagnose and monitor patients that report non-celiac gluten sensitivity," she said. - Christina Tennyson, MD, Assistant Professor, Gastroenterology, Icahn School of Medicine at Mount Sinai Learn more: https://consumer.healthday.com/vitamins-and-nutrition-information-27/gluten-975/is-non- celiac-gluten-sensitivity-real-713362.html If you have a news story, news tip, breakthrough, study, upcoming event or patient success story to share or have been contacted by the media for an interview contact: [email protected] 212-241-9200 This message and any attachments are confidential and intended solely for the use of the individual or entity to which they are addressed. If you are not the intended recipient, you are prohibited from printing, copying, forwarding, saving, or otherwise using or relying upon them in any manner. Please notify the sender immediately if you have received this message by mistake and delete it from your system. From: ITNDaily on behalf of Kozar, Matt Subject: Mount Sinai In The News - July 28, 2016 Date: Thursday, July 28, 2016 1:25:51 PM Attachments: ATT00003.txt In the News July 28, 2016 National Pain Report – July 28 Buprenorphine Implant May Help Opioid-Dependent People Better Adhere to Treatment A study published in JAMA by researchers from the Icahn School of Medicine at Mount Sinai investigated subdermal (under the skin) buprenorphine implants and their effect on opioid-dependent patients. They found that after six months patients’ maintained very low or no illicit use of opioids relative to daily sublingual (under the tongue) buprenorphine maintenance treatment.
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