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2 an Overview of Tick-Borne Diseases Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases Committee on Lyme Disease and Other Tick-Borne Diseases: The State of the Science; Institute of Medicine ISBN: 0-309-21110-7, 520 pages, 6 x 9, (2011) This free PDF was downloaded from: http://www.nap.edu/catalog/13134.html Visit the National Academies Press online, the authoritative source for all books from the National Academy of Sciences, the National Academy of Engineering, the Institute of Medicine, and the National Research Council: • Download hundreds of free books in PDF • Read thousands of books online, free • Sign up to be notified when new books are published • Purchase printed books • Purchase PDFs • Explore with our innovative research tools Thank you for downloading this free PDF. If you have comments, questions or just want more information about the books published by the National Academies Press, you may contact our customer service department toll-free at 888-624-8373, visit us online, or send an email to [email protected]. This free book plus thousands more books are available at http://www.nap.edu. Copyright © National Academy of Sciences. Permission is granted for this material to be shared for noncommercial, educational purposes, provided that this notice appears on the reproduced materials, the Web address of the online, full authoritative version is retained, and copies are not altered. To disseminate otherwise or to republish requires written permission from the National Academies Press. Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases http://www.nap.edu/catalog/13134.html Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases: The Short-Term and Long-Term Outcomes Workshop Report Committee on Lyme Disease and Other Tick-Borne Diseases: The State of the Science Board on Population Health and Public Health Practice PREPUBLICATION COPY: UNCORRECTED PROOFS Copyright © National Academy of Sciences. All rights reserved. Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases http://www.nap.edu/catalog/13134.html THE NATIONAL ACADEMIES PRESS 500 Fifth Street, N.W. Washington, DC 20001 NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance. This project was supported by Contract No. N01-OD-4-2139 between the National Academy of Sciences and the National Institutes of Health. Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the author(s) and do not necessarily reflect the view of the organizations or agencies that provided support for this project. International Standard Book Number 0-309-XXXXX-X (Book) International Standard Book Number 0-309- XXXXX -X (PDF) Library of Congress Control Number: 00 XXXXXX Additional copies of this report are available from the National Academies Press, 500 Fifth Street, N.W., Lockbox 285, Washington, DC 20055; (800) 624-6242 or (202) 334-3313 (in the Washington metropolitan area); Internet, http://www.nap.edu. For more information about the Institute of Medicine, visit the IOM home page at www.iom.edu. Copyright 2011 by the National Academy of Sciences. All rights reserved. Printed in the United States of America. The serpent has been a symbol of long life, healing, and knowledge among almost all cultures and religions since the beginning of recorded history. The serpent adopted as a logotype by the Institute of Medicine is a relief carving from ancient Greece, now held by the Staatliche Museen in Berlin. IOM (Institute of Medicine). 2011. Critical needs and gaps in understanding prevention, amelioration, and resolution of Lyme and other tick-borne diseases: the short-term and long-term outcomes. Washington, DC: The National Academies Press. Cover images courtesy of the Centers for Disease Control and Prevention. PREPUBLICATION COPY: UNCORRECTED PROOFS Copyright © National Academy of Sciences. All rights reserved. Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases http://www.nap.edu/catalog/13134.html PREPUBLICATION COPY: UNCORRECTED PROOFS Copyright © National Academy of Sciences. All rights reserved. Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases http://www.nap.edu/catalog/13134.html The National Academy of Sciences is a private, nonprofit, self-perpetuating society of distinguished scholars engaged in scientific and engineering research, dedicated to the furtherance of science and technology and to their use for the general welfare. Upon the authority of the charter granted to it by the Congress in 1863, the Academy has a mandate that requires it to advise the federal government on scientific and technical matters. Dr. Ralph J. Cicerone is president of the National Academy of Sciences. The National Academy of Engineering was established in 1964, under the charter of the National Academy of Sciences, as a parallel organization of outstanding engineers. It is autonomous in its administration and in the selection of its members, sharing with the National Academy of Sciences the responsibility for advising the federal government. The National Academy of Engineering also sponsors engineering programs aimed at meeting national needs, encourages education and research, and recognizes the superior achievements of engineers. Dr. Charles M. Vest is president of the National Academy of Engineering. The Institute of Medicine was established in 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public. The Institute acts under the responsibility given to the National Academy of Sciences by its congressional charter to be an adviser to the federal government and, upon its own initiative, to identify issues of medical care, research, and education. Dr. Harvey V. Fineberg is president of the Institute of Medicine. The National Research Council was organized by the National Academy of Sciences in 1916 to associate the broad community of science and technology with the Academy’s purposes of furthering knowledge and advising the federal government. Functioning in accordance with general policies determined by the Academy, the Council has become the principal operating agency of both the National Academy of Sciences and the National Academy of Engineering in providing services to the government, the public, and the scientific and engineering communities. The Council is administered jointly by both Academies and the Institute of Medicine. Dr. Ralph J. Cicerone and Dr. Charles M. Vest are chair and vice chair, respectively, of the National Research Council. www.national-academies.org . PREPUBLICATION COPY: UNCORRECTED PROOFS Copyright © National Academy of Sciences. All rights reserved. Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases http://www.nap.edu/catalog/13134.html MEMBERS OF THE COMMITTEE ON LYME DISEASE AND OTHER TICK-BORNE DISEASES: THE STATE OF THE SCIENCE LONNIE J. KING, D.V.M., (Chair) Dean, The Ohio State University, Columbus, OH NAOMI L. GERBER, M.D., Director, Center for the Study of Chronic Illness & Disability, George Mason University, Fairfax, VA STEPHEN M. OSTROFF, M.D., Director, Bureau of Epidemiology, Pennsylvania Department of Health, Harrisburg, VA GUY H. PALMER, D.V.M., Ph.D., Regents Professor of Pathology and Infectious Diseases; The Creighton Chair and Director of the School for Global Animal Health, Washington State University, Pullman, WA GORDON E. SCHUTZE, M.D., Professor and Vice-Chairman for Educational Affairs, Department of Pediatrics, Vice President, Baylor International Pediatric AIDS Initiative, Baylor College of Medicine, Texas Children's Hospital, Houston, TX DAVID H. WALKER, M.D., The Carmage and Martha Walls Distinguished University Chair in Tropical Diseases, Professor and Chair, Department of Pathology, Executive Director, Center for Biodefense and Emerging Infectious Disease, University of Texas Medical Branch-Galveston, Galveston, TX Study Staff CHRISTINE M COUSSENS, Ph.D., Senior Program Officer and Study Director, Board on Population Health and Public Health Practice CAROL MASON SPICER, Ph.D., Associate Program Officer, Board on Population Health and Public Health Practice (from December 2010) RITA DENG, M.H.S., Associate Program Officer, Board on Population Health and Public Health Practice (until October 2010) TREVONNE WALFORD, B.S., Research Assistant, Board on Population Health and Public Health Practice PAM LIGHTER, B.S., Senior Program Assistant, Board on Population Health and Public Health Practice (until April 2010) HOPE HARE, M.A., Adminstrative Assistant, Board on Population Health and Public Health Practice ANDREA BANKOSKI. B.S., Consultant SANDRA HACKMAN, B.A. Consultant ROSE MARIE MARTINEZ, Sc.D., Director, Board on Population Health and Public Health Practice PATRICK KELLEY, M.D.,
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