Dr. Elizabeth Ann Esterl, RN October 10, 2017

CURRICULUM VITAE

Biographical Data

Name: Dr. Elizabeth Ann Esterl, RN

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Professional Objective

Transformation and Servant Nursing & Hospital Leadership, Research, and Education

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Education

2012-2015 Regis University Denver, Colorado Major- Doctor of Nursing Practice Specialization- Advanced Leadership in Health Care Graduation Honors: Graduate Honors

2000-2002 Regis University Denver, Colorado Major- Master of Science in Nursing Specialization- Leadership in Healthcare Systems Graduation Honors: Graduate Honors

1996-1997 Regis University Denver, Colorado Major- Bachelor of Science in Nursing Graduation Honors: Summa Cum Laude Elected to membership Sigma Theta Tau (1997) and Alpha Sigma Nu (1997)

1981-1983 Arapahoe Community College Littleton Colorado Major – Associate of Arts Registered Nursing

1977-1981 Metropolitan State College Denver, Colorado Major - Liberal Arts

1975-1976 Dekalb Community College Atlanta, Georgia

Certification

Certified Clinical Research Coordinator Basic Life Support

1 Dr. Elizabeth Ann Esterl, RN October 10, 2017

Pediatric Advanced Life Support PICC Line Insertion- expired

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Membership

Sigma Theta Tau - Alpha Chapter at Large since 1997 Alpha Sigma Nu- since 1997 American Academy Allergy, Asthma, and Immunology American Nurses Association Colorado Nurses Association Pediatric Nurses Association Association of Clinical Research Professionals Society of Clinical Research Administrators

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Nursing License

State of Colorado Registered Nursing License - 76685 State of California Registered Nursing License- active State of Oregon Registered Nursing License- active State of Tennessee Registered Nursing License- expired

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Professional Experience

2017-present Ignatian Faculty Scholars Program Regis University Denver, Colorado Affiliated Faculty Scholar

2016-present Friendship Bridge Nursing Project- Vietnam. Ho Chi Minh City, Vietnam Visiting Professor- Nursing Research

2011-present National Jewish Health Denver, Colorado Senior Nursing Leadership Pediatric Director- Inpatient, Outpatient, Triage, Offsite Clinics and Research Projects Principal Investigator- Clinical Research protocols

2003-present Regis University Denver, Colorado Clinical Faculty- Online and Traditional Classroom Undergraduate and Graduate Nursing Program

2009-2014 University of Phoenix Denver, Colorado Clinical Faculty- Online Graduate Nursing Research Program

2011-2011 iC42 Laboratory Aurora, Colorado

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Business Manager, Clinical Research Operations Consultant

1997-2011 The Children’s Hospital Denver, Colorado Director - Clinical Trials Organization

1988-1997 National Jewish Medical and Research Center Denver, Colorado Program Coordinator - Immunology Infusion Room Program Coordinator - Pediatric Clinical Trials Program

1988 University Hospital Denver, Colorado R.N. - Pediatric Medical Unit Charge Nurse

1987 University of California Davis Medical Center Sacramento, California R.N. - Level II Nursery

1984-1987 The Children’s Hospital Denver, Colorado R.N. III - Pediatric Medical-Surgical Unit Home Health Level II Nursery Charge Nurse Graduate Nurse Preceptor

1983 LeBonheur Children’s Medical Center Memphis, Tennessee Pediatric Nurse Internship Program ______

Research Research National Jewish Medical and Research Center Denver, Colorado

OPEN LABEL STUDY OF HIGH DOSE INTRAVENOUS IMMUNOGLOBULIN IN 1991 SEVERE CHILDHOOD ASTHMA. SANDOZ PHARMACEUTICALS.

OPEN LABEL TRIAL OF HIGH DOSE INTRAVENOUS IMMUNOGLOBULIN IN 1991 SEVERE ADULT ATOPIC DERMATITIS. SANDOZ PHARMACEUTICALS.

THE USE OF INTRAVENOUS IMMUNOGLOBULIN IN ADULTS AND PEDIATRIC 1993 STEROID DEPENDENT ASTHMATICS. MILES INC.

1995 DOUBLE BLIND IVIG STUDY AND HYPOGAMMAGLOBULINEMIA PATIENTS. CENTEON.

DOUBLE BLIND, DOSE RANGING STUDY COMPARING PRODUCTS IN 1995 TREATMENT OF ASTHMA IN CHILDREN. RHONE-POULEC RORER PHARMACEUTICALS, INC.

DOUBLE BLIND, RANDOMIZED, PARALLEL GROUP STUDY COMPARING 1995 PRODUCT TO PLACEBO IN CHILDREN WITH CHRONIC ASTHMA. MERCK &

3 Dr. Elizabeth Ann Esterl, RN October 10, 2017

CO.

1995 PREDNISONE PRODUCT COMPARISON STUDY. DURA PHARMACEUTICALS.

A PILOT STUDY ON THE MECHANISMS UNDERLYING STEROID REDUCTION IN 1996 SEVERE ASTHMATICS TREATED WITH IVIG. BAYER PHARMACEUTICALS.

A RANDOMIZED, DOUBLE BLIND, PARALLEL GROUP CLINICAL TRIAL ASSESSING THE SAFETY AND EFFICACY OF ALBUTEROL POWDER VS. 1996 AEROSOL VS. INHALER VS. PLACEBO IN CHILDREN. GLAXO WELLCOME INC.

MULTICENTERED, DOUBLE BLIND, PLACEBO CONTROLLED STUDY TO 1996 EVALUATE THE SAFETY AND EFFICACY OF ANTI IGE RECOMBINANT HUMANIZED MONOCLONAL ANTIBODY. GENENTECH.

MULTICENTERED, RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED, PARALLEL GROUP STUDY OF THE SAFETY AND EFFICACY OF LOW DOSE 1996 ALBUTEROL SOLUTION IN CHILDREN. DEY LABORATORIES.

A COMPARISON STUDY OF BECLOMETHASONE DIPROPIONATE VS PLACEBO 1997 IN PEDIATRIC PATIENTS WITH SYMPTOMATIC ASTHMA. 3M PHARMACEUTICALS, INC. Research Clinical trials Organization at The Children’s Hospital- Denver, Colorado 2008 A 12-MONTH OPEN-LABEL EXTENSION STUDY EVALUATING THE SAFETY AND TOLERABILITY OF FLEXIBLE DOSES OF PREGABALIN IN PEDIATRIC PATIENTS WITH PARTIAL ONSET SEIZURES PROTOCOL NUMBER: A0081075 2008 A PHASE 3, RANDOMIZED, DOUBLE-BLIND, MULTI-CENTER STUDY TO COMPARE THE EFFICACY AND SAFETY OF MICAFUNGIN VERSUS AMPHOTERICIN B DEOXYCHOLATE FOR THE TREATMENT OF NEONATAL CANDIDIASIS. PROTOCOL 04-0-199 2008 AN OPEN-LABEL SAFETY AND TOLERABILITY STUDY OF IMMEDIATE-RELEASE AND EXTENDED-RELEASE OXYMORPHONE IN OPIOID-TOLERANT PEDIATRIC SUBJECTS WITH CHRONIC PAIN - STUDY EN3202-036 2008 AN OPEN-LABEL, ASCENDING, TWO-PART, SINGLE- AND MULTIPLE- DOSE EVALUATION OF THE SAFETY, PHARMACOKINETICS, AND EFFECTIVENESS OF OXYMORPHONE FOR ACUTE POSTOPERATIVE PAIN IN PEDIATRIC SUBJECTS 2008 GENETIC EPIDEMIOLOGY OF LIFE-THREATENING INFLUENZA INFECTION IN CHILDREN AND YOUNG ADULTS 2008 LONGITUDINAL STUDY OF MITOCHONDRIAL HEPATOPATHY 2008 PHARMACOGENOMICS IN PULMONARY ARTERIAL HYPERTENSION 2008 PHASE II/III DOUBLE BLIND, RANDOMIZED, PLACEBO CONTROLLED, CLINICAL TRIAL TO DETERMINE THE SAFETY AND EFFICACY OF INTRAVENOUS L-CITRULLINE VERSUS PLACEBO IN CHILDREN UNDERGOING CARDIOPULMONARY BYPASS 2008 TRIAL OF BETA BLOCKER THERAPY (ATENOLOL) VS. ANGIOTENSIN II RECEPTOR BLOCKER THERAPY (LOSARTAN) IN INDIVIDUALS WITH MARFAN SYNDROME. PROTOCOL NO. AGO/2006/009

4 Dr. Elizabeth Ann Esterl, RN October 10, 2017

13-Jul-99 A PROSPECTIVE, LONGITUDINAL STUDY OF CHILDHOOD PULMONARY HYPERTENSION 11-Feb-00 A DOUBLE-BLIND, PLACEBO-CONTROLLED, VIROLOGIC EFFICACY TRIAL OF PLECONARIL (VP63843) IN THE TREATMENT OF NEONATES WITH EV SEPSIS SYNDROME (PROTOCOL VERSION 5.0/REVISED DATE 04-07-2006) 25-Apr-00 COLCHICINE THERAPY IN CHILDHOOD CIRRHOSIS 01-May-00 MAGNESIUM AND METABOLIC BONE DISEASE IN CHRONIC LIVER DISEASE 17-May-00 A MULTICENTER GROUP TO STUDY ACUTE LIVER FAILURE 17-Jul-03 STUDIES IN PEDIATRIC LIVER TRANSPLANTATION (SPLIT) 11-Sep-03 A MULTICENTER, RANDOMIZED, DOUBLE-BLIND PLACEBO- CONTROLLED STUDY TO TEST THE SAFETY AND EFFICACY OF LIPITOR (ATORVASTATIN) IN REDUCING THE PROGRESSION OF CAROTID IMT IN EARLY CHILDHOOD SLE. THE ATHEROSCLEROSIS PREVENTION IN PEDIATRIC LUPUS ERYTHEMATOSUS (APPLE)STUDY. 17-Oct-03 A MULTI-CENTER STUDY OF THE SAFETY AND EFFICACY OF N- ACETYLCYSTEINE IN THE TREATMENT OF ACUTE LIVER FAILURE NOT CAUSED BY ACETAMINOPHEN IN PEDIATRIC PATIENTS 22-Oct-03 ASSESSMENT OF INTER-OBSERVER VARIABILITY IN THE HISTOLOGICAL DIAGNOSIS OF INFANTILE CHOLESTASIS 09-Dec-03 A RETROSPECTIVE STUDY OF BILIARY ATRESIA PATIENTS UP TO 2 YEARS OF AGE 23-Apr-04 A MULTICENTER, LONG-TERM EXTENSION STUDY TO ASSESS SAFETY OF ORAL SILDENAFIL IN THE TREATMENT OF SUBJECTS WHO HAVE COMPLETED STUDY A1481131 - (PROTOCOL # A1481156- 1005) 11-May-04 BILIARY ATRESIA CLINICAL RESEARCH CONSORTIUM (BARC): A PROSPECTIVE DATABASE OF INFANTS WITH CHOLESTASIS 30-Jun-04 PEGYLATED INTERFERON +/- RIBAVIRIN FOR CHILDREN WITH HCV 12-Aug-04 CHILDHOOD ABSENCE EPILEPSY RX, PK-PD-PHARMACOGENETICS 07-Dec-04 MANAGEMENT OF HIV-INFECTED PREGNANT WOMEN 20-Jul-05 A RANDOMIZED, DOUBLE-BLINDED, PLACEBO-CONTROLLED TRIAL OF CORTICOSTEROID THERAPY FOLLOWING PORTOENTEROSTOMY IN INFANTS WITH BILIARY ATRESIA 16-Sep-05 FUNCTIONAL OUTCOMES IN PEDIATRIC LIVER TRANSPLANT 25-Oct-05 AN OPEN-LABEL, LONG-TERM, SAFETY, AND TOLERABILITY EXTENSION STUDY USING THE PEDIATRIC FORMULATION OF BOSENTAN IN THE TREATMENT OF CHILDREN WITH IDIOPATHIC OR FAMILIAL PULMONARY ARTERIAL HYPERTENSION WHO COMPLETED FUTURE 1: FUTURE 2 AC-052-367 07-Feb-06 A PHASE III, OPEN-LABEL, NON-RANDOMIZED, INTERNATIONAL, MULTICENTER TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF CARDIOLITE MYOCARDIAL PERFUSION IMAGING IN PEDIATRIC SUBJECTS WITH KAWASAKI DISEASE

5 Dr. Elizabeth Ann Esterl, RN October 10, 2017

22-Feb-06 RETROSPECTIVE LUNG BIOPSY PATHOLOGY REVIEW WITH IMAGING AND CLINICAL CORRELATION FOR CHILDREN AGES 2-18 WITH DIFFUSE LUNG DISEASE 12-Apr-06 A 16-WEEK, INTERNATIONAL, MULTICENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED COMPARISON OF THE EFFICACY AND SAFETY OF ORAL UT-15C SUSTAINED RELEASE TABLETS IN COMBINATION WITH AN ENDOTHELIN RECEPTOR ANTAGONIST AND/OR A PHOSPHODIESTERASE-5 INHIBITOR IN SUBJECTS WITH PULMONARY ARTERIAL HYPERTENSION PROTOCOL NUMBER: TDE-PH-301 12-Apr-06 AN OPEN-LABEL EXTENSION TRIAL OF UT-15C SR IN SUBJECTS WITH PULMONARY ARTERIAL HYPERTENSION PROTOCOL NUMBER: TDE- PH-304 14-Jul-06 BILIARY ATRESIA STUDY IN INFANTS AND CHILDREN (BASIC) - SPONSOR PROJECT NUMBER P005 18-Aug-06 TREATMENT OF CLOGGED TYMPANOSTOMY TUBES: AN OFF-LABEL USE OF DORNASE ALFA (PULMOZYME) STUDY NUMBER Z3816S 15-Sep-06 A MULTI-CENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED RANDOMIZED, EFFICACY AND SAFETY STUDY OF DENUFOSOL TETRASODIUM (INS37217) INHALATION SOLUTION IN PATIENTS WITH MILD CYSTIC FIBROSIS LUNG DISEASE. 12-Jan-07 A PHARMACOKINETIC/ PHARMACODYNAMIC AND SAFETY EVALUATION OF OSELTAMIVIR (TAMIFLU) FOR THE TREATMENT OF CHILDREN LESS THAN 24 MONTHS OF AGE WITH CONFIRMED INFLUENZA INFECTION (CASG 114) DMID PROTOCOL NUMBER 06- 0059, ROCHE PROTOCOL NUMBER: WP-20749 14-Mar-07 INTERNATIONAL, RANDOMIZED, DOUBLE BLIND CLINICAL STUDY EVALUATING THE EFFICACY AND SAFETY OF CLOPIDOGREL 0.2MG/KG ONCE DAILY VERSES PLACEBO IN NEONATES AND INFANTS WITH CYANOTIC CONGENTIAL HEART DISEASE PALLIATED WITH A SYSTEMIC-TO-PULMONARY ARTERY SHUNT (I.E. MODIFIED BLALOCK TAUSSIG SHUNT) PROTOCOL NO. EFC5314 21-Mar-07 A PHASE 3, OPEN-LABEL, RANDOMIZED, PARALLEL-GROUP, MULTI- CENTER STUDY TO EVALUATE THE SAFETY AND IMMUNOGENICITY OF NOVARTIS MENINGOCOCCAL ACWY CONJUGATE VACCINE WHEN ADMINISTERED WITH ROUTINE INFANT VACCINATIONS TO HEALTHY INFANTS PROTOCOL V59P14, INFANTS - US 06-Apr-07 A MULTI-CENTER, DOUBLE BLIND STUDY TO EVALUATE THE SAFETY, EFFICACY AND PHARMACOKINETICS OF THE HUMAN ANTI- TNF MONOCLONAL ANTIBODY ADALIMUMAB IN PEDIATRIC SUBJECTS WITH MODERATE TO SEVERE CROHN'S DISEASE 17-May-07 A MULTICENTER, PROSPECTIVE, LONG-TERM, OBSERVATIONAL REGISTRY OF PEDIATRIC PATIENTS WITH INFLAMMATORY BOWEL DISEASE 19-Sep-07 A LONG-TERM SAFETY STUDY OF A COMBINATION PRODUCT CONTAINING SUMATRIPTAN SUCCINATE AND NAPROXEN SODIUM FOR THE TREATMENT OF MIGRAINE IN ADOLESCENTS 29-Sep-07 LONGITUDINAL STUDY OF GENETIC CAUSES OF INTRAHEPATIC CHOLESTASIS

6 Dr. Elizabeth Ann Esterl, RN October 10, 2017

05-Oct-07 A PHASE 1, OPEN-LABEL STUDY OF THE SAFETY AND PHARMACOKINETICS OF REPEATED-DOSE MICAFUNGIN AS ANTIFUNGAL PROPHYLAXIS IN CHILDREN AND ADOLESCENTS UNDERGOING HEMATOPOIETIC STEM CELL TRANSPLANTATION 08-Nov-07 STUDIES OF PRIMARY SCLEROSING CHOLANGITIS (STOPSC) 14-Dec-07 A PHASE III, RANDOMIZED, PLACEBO-CONTROLLED, BLINDED INVESTIGATION OF SIX WEEKS VS. SIX MONTHS OF ORAL VALGANCICLOVIR THERAPY IN INFANTS WITH SYMPTOMATIC CONGENITAL CYTOMEGALOVIRUS INFECTION (CASG 112) 02-Jan-08 PILOT STUDY TO DEFINE NUTRITIONAL INTERRELATIONSHIPS OF CO-ENZYME Q10, RIBOFLAVIN AND MAGNESIUM IN THE EVALUATION AND TREATMENT OF CHILDHOOD MIGRAINE HEADACHES. 21-Mar-08 A PHASE 3, INTERNATIONAL, MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP EFFICACY AND SAFETY STUDY OF DENUFOSOL TETRASODIUM INHALATION SOLUTION IN PATIENTS WITH CYSTIC FIBROSIS LUNG DISEASE AND FEV1 GREATER THAT 75% PREDICTED A PHASE 3, INTERNATIONAL, MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP EFFICACY AND SAFETY STUDY OF DENUFOSOL TETRASODIUM INHALATION SOLUTION IN PATIENTS WITH CYSTIC FIBROSIS LUNG DISEASE AND FEV1 GREATER THAN 75% PREDICTED 25-Mar-08 A MULTICENTER INTERNATIONAL STUDY OF THE LONG-TERM SAFETY OF INFLIXIMAB (REMICADE) IN ULCERATIVE COLITIS - PROTOCOL C0168T62 27-Mar-08 DOUBLE-BLIND, PLACEBO-CONTROLLED, EFFICACY AND SAFETY STUDY OF CLOBAZAM (0.25, 0.5 AND 1.0 MG/KG/DAY) IN PATIENTS WITH LENNOX-GASTAUT SYNDROME PROTOCOL NUMBER: OV-1012 WIRB #: 20071216 28-Mar-08 A PHASE 2, RANDOMIZED, OPEN-LABEL, PARALLEL-GROUP, MULTICENTER TRIAL TO EVALUTE THE SAFETY AND EFFICACY OF INFLIXIMAB (REMICADE) IN PEDIATRIC SUBJECTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS - PROTOCOL C0168T72 03-Apr-08 SAFETY AND EFFECTIVENESS OF OPEN-LABEL CLOBAZAM IN SUBJECTS WITH LENNOX-GASTAUT SYNDROME. PROTOCOL OV-1004 24-Apr-08 SAFETY AND EFFICACY OF EXENATIDE AS MONOTHERAPY AND ADJUNCTIVE THERAPY TO ORAL ANTIDIABETIC AGENTS IN ADOLESCENTS WITH TYPE 2 DIABETES. 25-Apr-08 AN EFFICACY AND SAFETY STUDY OF RESLIZUMAB (CTX55700) IN THE TREATMENT OF EOSINOPHILIC ESOPHAGITIS IN SUBJECTS AGED 5 TO 18 YEARS 14-May-08 COLORADO CLINICAL TRANSLATIONAL SCIENCE INSTITUTE (CCTSI) 28-May-08 A PHASE 2B EFFICACY AND SAFETY STUDY OF PTC124 IN SUBJECTS WITH NONSENSE-MUTATION- MEDIATED DUCHENNE AND BECKER MUSCULAR DYSTROPHY 02-Jun-08 GORE HELEX™ SEPTAL OCCLUDER POST APPROVAL STUDY

7 Dr. Elizabeth Ann Esterl, RN October 10, 2017

18-Jun-08 A PLACEBO-CONTROLLED, ESCALATING DOSE, MULTIPLE DOSE STUDY TO EVALUATE THE SAFETY, TOLERABILITY AND PHARMACOKINETICS OF PREGABALIN IN PEDIATRIC PATIENTS WITH PARTIAL ONSET SEIZURES PROTOCOL NUMBER: A0081074 25-Jul-08 TREATMENT OPTIONS FOR TYPE 2 DIABETES IN ADOLESCENTS AND YOUTH (TODAY): GENETICS STUDY 25-Aug-08 HMP 4009: A MULTICENTER, INPATIENT, OPEN-LABEL, WITHIN SUBJECT DOSE TITRATION STUDY TO CHARACTERIZE THE PHARMACOKINETICS/PHARMACODYNAMICS, SAFETY AND EFFICACY OF HYDROMORPHONE HCL ORAL SOLUTION IN SUBJECTS FROM 28 DAYS TO 16 YEARS OF AGE, INCLUSIVE, WHO REQUIRE OPIOID ANALGESICS FOR POST-OPERATIVE PAIN 26-Aug-08 PEDIATRIC FUNGAL NETWORK DATABASE 26-Sep-08 AN OPEN-LABEL SAFETY AND EFFICACY STUDY OF RESLIZUMAB (CTX55700) FOR THE TREATMENT OF PEDIATRIC SUBJECTS WITH EOSINOPHILIC ESOPHAGITIS WHO COMPLETED STUDY RES-5-0002 (PROTOCOL RES-5-0004) WIRB #: 20080586 15-Oct-08 RSV AND PIV3 IMMUNOLOGY PILOT 21-Nov-08 ORAL VISCOUS BUDESONIDE SUSPENSION (MB-7) IN SUBJECTS WITH EOSINOPHILIC ESOPHAGITIS: A RANDOMIZED, PLACEBO- CONTROLLED, DOSE-RANGING STUDY IN CHILDREN AND ADOLESCENTS WIRB #: 20081925 25-Nov-08 PHARMACOKINETICS AND SAFETY OF AMBRISENTAN IN CHILDREN WITH PULMONARY ARTERIAL HYPERTENSION 03-Dec-08 PILOT STUDY FOR BIOMARKERS FOR SPINAL MUSCULAR ATROPHY 09-Mar-99 TELEPHONE SURVEY OF PARENTS CALLING AN AFTER-HOURS CALL CENTER 14-Jul-99 SICKLE CELL DISEASE AND OBSTRUCTIVE SLEEP APNEA 23-Aug-99 FILGRASTIM-MOBILIZED PERIPHERAL BLOOD STEM CELLS FOR PRIMARY ALLOGENEIC TRANSPLANTATION WITH UNRELATED DONORS 11-Nov-99 THE LONG TERM SAFETY AND EFFICACY OF RISPERIDAL IN CONDUCT DISORDER IN MILD MODERATE, AND BORDERLINE MENTALLY RETARDED CHILDREN AGED 5-14 YEARS 11-Nov-99 A MULTICENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO- CONTROLLED, PARALLEL STUDY OF THE SAFETY AND EFFICACY OF BOTOX (BOTULINUM TOXIN TYPE A) PURIFIED NEUROTOXIN COMPLEX FOR THE TREATMENT OF INCREASED MUSCLE TONE OF THE LOWER LIMB RESULTING IN ABNORMAL GAIT ASSOCIATED WITH PEDIATRIC CEREBRAL PALSY 15-Nov-99 EVALUATION OF ENROLLMENT INTO THE COLORADO CHILD HEALTH PLAN 17-Nov-99 A MULTI-CENTER, OPEN LABEL STUDY OF THE EFFICACY AND SAFETY OF EXISULIND AT THE HIGHEST TOLERATED DOSE IN PEDIATRIC PATIENTS WITH INTACT COLONS AND A DIAGNOSIS OF ADENOMATOUS POLYPOSIS COLI (APC) 17-Nov-99 A STUDY OF THE SAFETY, TOLERANCE AND EFFICACY OF

8 Dr. Elizabeth Ann Esterl, RN October 10, 2017

PALIVIZUMAB (MEDI-493, SYNAGIS) FOR PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS IN CHILDREN WITH CONGENITAL HEART DISEASE 18-Nov-99 AN OPEN-LABEL, NON-COMPARATIVE STUDY OF FK463 FOR THE TREATMENT OF INVASIVE ASPERGILLOSIS 18-Nov-99 ASSESSING THE SAFETY AND EFFICACY OF DIASTAT (DIAZEPAM RECTAL GEL) FOR THE TREATMENT OF FEBRILE SEIZURES 22-Nov-99 SURVEY OF HOSPITAL POLICIES AND PROCEDURES FOR NEONATAL HEPATITIS B VACCINE 22-Nov-99 CELL-MEDIATED IMMUNE FUNCTION IN HIV INFECTED PATIENTS COMPARED WITH UNINFECTED CONTROLS 23-Nov-99 ADOLESCENT ATTITUDES ABOUT PREGNANCY 23-Nov-99 THE EFFECT OF RECOMBINANT HUMAN GROWTH HORMONE TREATMENT ON THE GROWTH OF INFANTS AND TODDLERS WITH TURNER SYNDROME 24-Nov-99 OPEN-LABEL, MULTICENTER TRIAL TO EVALUATE THE SAFETY AND IMMUNOGENICITY OF A FIFTH CONSECUTIVE DOSE (BOOSTER) OF CERTIVA IN HEALTHY CHILDREN 24-Nov-99 AN OPEN-LABEL, NON-COMPARATIVE STUDY OF FK463 FOR THE TREATMENT OF CANDIDEMIA OR INVASIVE CANDIDIASIS 26-Nov-99 VALACYCLOVIR FOR THE TREATMENT OF HERPES ZOSTER IN IMMUNOCOMPROMISED CHILDREN 26-Nov-99 VALIDATION OF AN INNOVATIVE CLOSED DRUG DELIVERY SYSTEM IN CRITICALLY ILL NEONATES: EFFECT ON SEPSIS RATES AND DRUG STABILITY 30-Nov-99 AN EVALUATION OF THE PERFORMANCE OF THE CARDIOSEAL STARFLEX SEPTAL OCCLUSION SYSTEM IN PATIENTS WITH SECUNDUM ATRIAL SEPTAL DEFECT (ASD) 30-Nov-99 MANAGING INFANT IRRITABILITY: A CLINICAL TRIAL 01-Dec-99 THE EFFECTIVENESS OF SCHOOL-BASED SUPPORT GROUPS FOR ADOLESCENTS WITH AN ADDICTIVE PARENT 06-Dec-99 EFFECT OF INTENSIVE EPILEPSY TREATMENT ON HEALTH-RELATED QUALITY OF LIFE IN CHILDREN WITH MEDICALLY UNCONTROLLED EPILEPSY 07-Dec-99 DEVELOPMENT OF AN INTELLIGENT PHONCARDIOGRAPHIC SCREENING DEVICE - USING ADVANCED SIGNAL PROCESSING & NEURAL NETWORKS 08-Dec-99 A RANDOMIZED, DOUBLE-BLIND, PARALLEL GROUP, MONOTHERAPY STUDY TO COMPARE THE SAFETY AND EFFICACY OF TWO DOSES OF TOPIRAMATE IN THE TREATMENT OF NEWLY DIAGNOSED OR RECURRENT EPILEPSY 10-Dec-99 LATE STEROID RESCUE STUDY (LASRS) VERSION IV: THE EFFICACY OF CORTICOSTEROIDS AS RESCUE THERAPY FOR THE LATE PHASE OF ACUTE RESPIRATORY DISTRESS SYNDROME 10-Dec-99 PROSPECTIVE MULTIDISCIPLINARY ASSESSMENT OF NUTRITION AND HEALTH-RELATED QUALITY OF LIFE CHANGES IN CHILDREN

9 Dr. Elizabeth Ann Esterl, RN October 10, 2017

WITH REFRACTORY EPILEPSY TREATED WITH THE KETOGENIC DIET 20-Dec-99 AN OPEN, INTRAVENOUS STUDY TO EVALUATE THE PLASMA CONCENTRATION PROFILES OF MK-0826 IN PATIENTS AGED 3 MONTHS THROUGH 17 YEARS 20-Dec-99 A MULTICENTER, PLACEBO-CONTROLLED, 8-MONTH STUDY OF THE EFFECT OF TWICE DAILY CARVEDILOL IN CHILDREN WITH CONGESTIVE HEART FAILURE DUE TO SYSTEMIC VENTRICULAR SYSTOLIC DYSFUNCTION 20-Dec-99 EVALUTION OF PROJECT ENRICH'S HOME ACTIVITY AND PLAY INTERVENTION 21-Dec-99 CARDIOSEAL SEPTAL OCCLUDER SYSTEM FOR PATIENTS WITH VENTRICULAR SEPTAL DEFECT OR FENESTRATED FONTAN PROCEDURE UNDER HUMANITARIAN DEVICE EXEMPTION 22-Dec-99 A MULTICENTER STUDY TO EVALUATE THE PHARMACOKINETICS, DOSE-RESPONSE, EFFICACY, AND SAFETY OF BENAZEPRIL IN PEDIATRIC SUBJECTS 27-Dec-99 COMMUNITY HEALTH NETWORK CHILDHOOD IMMUNIZATION STUDY--POLIOVIRUS ANTIBODY SEROSURVEILLANCE 27-Dec-99 THE EFFECTS OF SECRETIN ON SYMPTOMS OF AUTISM 27-Dec-99 NUC30926, AN EXTENDED STRATIFIED FOLLOW-ON STUDY IN PEDIATRIC SUBJECTS WITH CHRONIC HEPATITIS B WHO HAVE COMPLETED PREVIOUS LAMIVUDINE STUDIES 29-Dec-99 AN INTERNATIONAL, MULTICENTER, UNCONTROLLED, OPEN EVALUATION OF CHRONIC UT-15 PLUS CONVENTIONAL THERAPY IN PATIENTS WITH PULMONARY HYPERTENSION: A CONTINUATION STUDY 29-Dec-99 EFFECT OF TOPIRAMATE ON SPIKE WAVE ACTIVITY ON THE EEG IN PATIENTS WITH PRIMARY GENERALIZED EPILIPSY 30-Dec-99 COMPUTER AND LABORATORY MODELING OF THE HEART WITH CLINICAL VALIDATION 04-Jan-00 METABOLIC AND IMMUNOGENETIC EVALUATION OF RELATIVES OF PATIENTS WITH TYPE I DIABETES EXPRESSING "BIOCHEMICAL" ANTI-ISLET AUTOANTIBODIES 07-Jan-00 ACTG316-(VERSION 4) A PHASE III RANDOMIZED, BLINDED STUDY OF NEVIRAPINE VS NEVIRAPINE PLACEBO FOR THE PREVENTION OF MATERNAL-FETAL TRANSMISSION IN PREGNANT HIV-INFECTED WOMEN WHO PRESENT DURING THE THIRD TRIMESTER OF PREGANCY 10-Jan-00 GENOTYPE PHENOTYPE RELATIONSHIPS IN FRAGILE X FAMILIES 10-Jan-00 VAGINAL DOUCHING IN ADOLESCENTS 10-Jan-00 TREATMENT OF GLUCOCORTICOID-INDUCED OSTEOPOROSIS WITH PAMIDRONATE IN CHILDREN AND ADOLESCENTS WITH SEVERE ASTHMA 13-Jan-00 THE HYPOPITUITARY CONTROL AND COMPLICATIONS STUDY 14-Jan-00 NITRIC OXIDE, NITRIC OXIDE METABOLITES, AND EXPRESSION OF INDUCIBLE NITRIC OXIDE SYNTHASE IN THE AIRWAYS OF INFANTS

10 Dr. Elizabeth Ann Esterl, RN October 10, 2017

AND CHILDREN WITH CYSTIC FIBROSIS 14-Jan-00 THE USE OF HOME OXYGEN IN THE OUTPATIENT MANAGEMENT OF BRONCHIOLITIS COMPLICATED BY HYPOXIA 14-Jan-00 MOLECULAR EXPRESSION OF THE FRAGILE X GENE 14-Jan-00 A MULTICENTER, RANDOMIZED, SINGLE-BLIND, PHARMACOKINETICS AND PHARMACODYNAMICS STUDY TO EVALUATE SINGLE AND MULTIPLE DOSES OF OMEPRAZOLE IN A PEDIATRIC POPULATION AGES 0 MONTHS-24 MONTHS, INCLUSIVE 14-Jan-00 DOUBLE BLIND, PLACEBO-CONTROLLED TRIAL OF VITAMIN E AS ADD-ON THERAPY FOR CHILDREN WITH EPILEPSY 17-Jan-00 OPEN-LABEL, NON-RANDOMIZED STUDY OF THE MIDDLE EAR FLUID PENETRATION OF GATIFLOXACIN IN CHILDREN UNDERGOING TYMPANOSTOMY TUBE PLACEMENT 17-Jan-00 A PHASE 111 PRETRANSPLANT B43-PAP IMMUNOTOXIN THERAPY IN CHILDREN WITH POOR PROGNOSIS B-LINEAGE ACUTE LYMPHOBLASTIC LEUKEMIA UNDERGOING BONE MARROW TRANSPLANTATION 20-Jan-00 A MULTICENTER, LONGITUDINAL FOLLOW-UP OF PATIENTS WITH CYSTIC FIBROSIS TO EVALUATE BREATHING FUNCTION, THE RATE OF RESPIRATORY TRACT INFECTION AND THE SAFETY OF LONG- TERM TREATMENT WITH PULMOZYME(PROTOCOL#Z0595N) 20-Jan-00 PULMONARY FUNCTION IN INFANTS WITH CYSTIC FIBROSIS 20-Jan-00 P1008 AN OBSERVATIONAL STUDY OF THE RATE OF OPPORTUNISTIC INFECTIONS EVENTS IN HIV-INFECTED CHILDREN WHO HAVE DEMONSTRATED IMMUNOLOGIC RECONSTITUTION AND WHO HAVE DISCONTINUED OI PROPHYLAXIS 21-Jan-00 PORTABLE KERATOMETRY: EFFECT OF DIFFERENT LID SPECULA IN PEDIATRIC PATIENTS UNDER GENERAL ANESTHESIA 21-Jan-00 PACTG 391- USE OF A LIVE-ATTENUATED VARICELLA-ZOSTER VIRUS (VZV) VACCINE TO BOOST IMMUNITY TO VZV IN HIV-INFECTED CHILDREN PREVIOUSLY INFECTED WITH VARICELLA (VERSION 3.0) 24-Jan-00 SERUM AMINO ACID CONCENTRATIONS AND NUTRITIONAL STATUS IN CHILDREN WITH SICKLE CELL DISEASE 26-Jan-00 CHARACTERIZATION OF CHROMOSOME 8P23.1 BREAKPOINTS 26-Jan-00 MELATONIN AND SLEEP STUDIES WITH CHILDREN WITH DEVELOPMENTAL DISABILITIES 27-Jan-00 PACTG 265 V 4.0 - PHASE I/II STUDY OF SAFETY AND IMMUNOGENICITY OF LIVE-ATTENUATED VARICELLA VACCINE (VARIVAX) IN HIV-INFECTED CHILDREN 03-Feb-00 MEASUREMENT OF METABOLIC SUBSTRATE TURNOVER RATES & INTERCONVERSION RATES IN LOW BIRTH WEIGHT INFANTS 04-Feb-00 PEDIATRIC LATE OUTCOMES PROTOCOL (ACTG 219C) 07-Feb-00 CULTURE AND DEVELOPMENT IN CHILDREN AGES 0-3 IN ONE INDIAN TRIBE 07-Feb-00 A DESCRIPTIVE STUDY ON THE USE OF A PEDIATRIC TREATMENT

11 Dr. Elizabeth Ann Esterl, RN October 10, 2017

ROOM 08-Feb-00 VAGUS NERVE STIMULATION PATIENT REGISTRY 09-Feb-00 MULTICENTER TRIAL OF SYNSORB PK IN E. COLI RELATED HEMOLYTIC UREMIC SYNDROME 09-Feb-00 PHASE I/II STUDY OF RITONAVIR THERAPY IN HIV-I INFECTED INFANTS AND CHILDREN ACTG-345 (VERSION 3.0) 10-Feb-00 EVALUATION OF COMPASSIONATE USE OF THE CARDIOSEAL DEVICE SEPTAL OCCLUSION SYSTEM 10-Feb-00 RECOMBINANT 8 SYNDROME: EXTENDING LABORATORY RESEARCH TO AN AT-RISK POPULATION 11-Feb-00 A DOUBLE-BLIND, PLACEBO-CONTROLLED, VIROLOGIC EFFICACY TRIAL OF PLECONARIL (VP63843) IN THE TREATMENT OF INFANTS WITH ENTEROVIRAL MENINGITIS (PROTOCOL VERSION 3.0/REVISED DATE 5/15/00) 11-Feb-00 NASAL POTENTIAL DIFFERENCE MEASUREMENTS IN PATIENTS WITH CYSTIC FIBROSIS AND NORMAL INDIVIDUALS 11-Feb-00 PERTUSSIS VACCINE EFFECTIVENESS STUDY 11-Feb-00 A RANDOMIZED, DOUBLE-BLIND, CONTROLLED STUDY OF AN INCREASE CALORIC DENSITY INFANT FORMULA AND ITS EFFECT ON GROWTH AND NUTRITIONAL STATUS IN HIV-INFECTED INFANTS (ACTG 247 VERSION 2.0) 11-Feb-00 TOBRAMYCIN IN YOUNG CYSTIC FIBROSIS PATIENTS 14-Feb-00 AN INQUIRY INTO THE UNDERSTANDING OF MATERNAL PKU IN HYPERPHENYLALANEMIC WOMEN 18-Feb-00 DOES IV LOADING IMPROVE EFFICACY OF ORAL AZATHIOPRINE IN TREATING CHILDREN WITH INFLAMMATORY BOWEL DISEASE 18-Feb-00 A STUDY TO INVESTIGATE USE OF NASAL NITIRIC OXIDE IN THE TREATMENT OF PULMONARY HYPERTENSION IN PEDIATRIC PATIENTS 23-Feb-00 AN OPEN-LABEL, MULTICENTER, NON-COMPARATIVE STUDY OF GATIFLOXACIN IN THE TREATMENT OF RECURRENT OTITIS MEDIA IN CHILDREN - PROTOCOL #AI420-076 23-Feb-00 INDENTIFICATION OF CHILDREN IN NEED OF REFERRAL FOR PART C SERVICES 24-Feb-00 FAMILY-CENTERED CARE IN A NICU SETTING; FAMILY/PARENT EXPECTATIONS AND PERCEPTIONS OF THEIR INFANT'S CARE IN AN URBAN PEDIATRIC HOSPITAL 24-Feb-00 HUMAN PRIMARY VASCULAR SMOOTH MUSCLE CELL CULTURE 24-Feb-00 BLOOD DRAW FOR PRE-CLINICAL IMMUNOTHERAPY LABORATORY INVESTIGATIONS 25-Feb-00 A CONTROLLED RANDOMIZED, PATIENT-MASKED PHASE II STUDY TO EVALUATE THE SAFETY AND EFFICACY OF TOPICAL CIPRO DEX (CIPROFLOXACIN 0.3%, DEXAMETHASONE 0.1%) SUSPENSION COMPARED TO CILOXAN (CIPROFLOXACIN 0.3%) SOLUTION IN THE TREATMENT OF ACUTE OTITIS MEDIA WITH TYMPANOSTOMY TUBES

12 Dr. Elizabeth Ann Esterl, RN October 10, 2017

(AOMT) 28-Feb-00 A SURVEY TO MEASURE ATTITUDES OF PATIENTS WITH CYSTIC FIBROSIS REGARDING PERCUTANEOUS ENDOSCOPIC GASTROSTOMY (PEG) TUBES 28-Feb-00 A STUDY TO ASSESS THE SAFETY, DOSE CONVERSION AND TITRATION OF DURAGESIC (FENTANYL TRANSDERMAL SYSTEM) IN PEDIATRIC SUBJECTS WITH CHRONIC PAIN REQUIRING OPIOID THERAPY 29-Feb-00 A MULTICENTER, INTERNATIONAL, RANDOMIZED, PLACEBO- CONTROLLED, DOUBLE-BLIND STUDY TO DETERMINE THE EFFECT OF PULMOZYME ON PULMONARY FUNCTION OVER 96 WEEKS IN SUBJECTS WITH CYSTIC FIBROSIS AGED 6-10 YEARS (PROTOCOL Z0713G) 29-Feb-00 THE EFFECTS OF EXOGENOUS INSULIN ON PROTEIN METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTS 02-Mar-00 CCC B947 - A GROUPWIDE PROTOCOL FOR COLLECTING AND BANKING TUMOR SPECIMENS 02-Mar-00 THE COLORADO ADOLESCENT MATERNITY PROJECT- SISTERS PROGRAM 06-Mar-00 DEVELOPMENTALLY-BASED MEDICATION INSTRUCTION 06-Mar-00 EFFECTS OF PUPILLARY DILATION AND CYCLOPLEGIA ON INTRAOCULAR PRESSURE IN A PEDIATRIC POPULATION 08-Mar-00 THE EFFECTS OF HOME VISITS ON MEDICATION ADHERENCE IN CHILDREN AND YOUTH WITH HIV. 08-Mar-00 EFFECT OF NICOTINE AND RELATED ALKALOIDS ON CELL CYCLE (A.K.A. EFFECT OF NICOTINE AND ITS MAJOR METABOLITIES ON THE LYMPHOCYTE CELL CYCLE) 09-Mar-00 THREE DIMENSIONAL ULTRASOUND METHODS FOR AORTIC STENOSIS: IN VITRO AND PROSPECTIVE CLINICAL STUDY 13-Mar-00 COMPARISON OF TWO DIFFERENT TECHNIQUES OF SPUTUM INDUCTION TO INVESTIGATE AIRWAY INFLAMMATION AND INFECTION IN CYSTIC FIBROSIS 13-Mar-00 CCG 1952 RANDOMIZED COMPARISON OF ORAL MERCAPTOPURINE VS ORAL THIOGUANINE & INTRATHECAL METHOTREXATE/ CYTARABINE/ HYDROCORTISONE FOR STANDARD RISK ACUTE LYMPHOBLASTIC LEUKEMIA 14-Mar-00 NURSING ASSESSSMENT OF INFANT PAIN: MODEL AND TOOL DEVELOPMENT 14-Mar-00 A MULTI-CENTER, OPEN-LABEL, LONG-TERM, FOLLOW-UP STUDY OF THE SAFETY AND EFFICACY OF UCB L059 (250 MG AND 500 MG TABLETS) IN CHILDREN WITH EPILEPSY 15-Mar-00 A PILOT STUDY TO DETERMINE THE EFFECTS OF TREADMILL TRAINING ON INFANTS BORN PRETERM WITH GRADE III OR GRADE IV INTRAVENTRICULAR HEMORRHAGE 15-Mar-00 THE EFFECTS OF THE PROBIOTIC AGENT LACTOBACILLUS CASEI GG ON FAT ABSORPTION, BACTERIAL OVERGROWTH AND HEPATIC

13 Dr. Elizabeth Ann Esterl, RN October 10, 2017

FUNCTION OF CHILDREN WITH SHORT BOWEL SYNDROME 16-Mar-00 THE EFFECTS OF INHALED NITRIC OXIDE IN THE TREATMENT OF ACUTE HYPOXEMIC RESPIRATORY FAILURE IN PEDIATRICS 16-Mar-00 CALCIUM AND ZINC HOMEOSTASIS IN CYSTIC FIBROSIS 20-Mar-00 INTER-NURSE RELIABILITY IN DETERMINING TRIAGE DISPOSITION WHEN USING STANDARDIZED PEDIATRIC TELEPHONE TRIAGE PROTOCOLS 20-Mar-00 PHASE I/II TRIAL OF RECOMBINANT INTERLEUKIN-2 IN SYMPTOMATIC HUMAN IMMUNODEFICIENCY VIRUS-INFECTED CHILDREN (VERSION 2.0 ACTG 299) 20-Mar-00 CYTOMEGALOVIRUS QUANTITATION IN WHITE BLOOD CELLS 24-Mar-00 INVESTIGATION OF THE EFFECT OF IMPLEMENTIATION OF COMPUTERIZED GROWTH CHARTS TO INCREASE COMPLIANCE OF CHARTING GROWTH PARAMETERS 24-Mar-00 INFLUENCE OF ENDOTHELIAL DERIVED FACTORS ON SICKLE RED BLOOD CELL ADHERENCE TO ENDOTHELIUM 27-Mar-00 RP59500V-324 OPEN LABEL, MULTICENTER, MULTIPLE DOSE, PHASE III STUDY OF THE POPULATION PHARMACOKINETICS OF IV SYNERCID (7.5 MG/KG Q 8H) IN 75 PEDIATRIC PATIENTS 27-Mar-00 REDUCING MEDICATION ERRORS THROUGH THE USE OF WIRELESS NETWORKS AND HAND-HELD COMPUTERS 29-Mar-00 A PROSPECTIVE RANDOMIZED STUDY TO COMPARE CIPROFLOXACIN WITH ESTABLISHED COMPARATIVE REGIMENS 03-Apr-00 IV IRON DEXTRAN INFUSION IN PEDIATRIC INFLAMMATORY BOWEL DISEASE 04-Apr-00 IMMUNE BILE DUCT INJURY IN CD154 DEFICIENCY (XHIM) 04-Apr-00 USE OF CHEST RADIOGRAPHS FOR EVALUATION OF FIRST TIME WHEEZING ILLNESSES 07-Apr-00 A RANDOMIZED, DOUBLE-BLINDED, PLACEBO-CONTROLLED, MULTICENTER STUDY OF THE SAFETY AND ACTIVITY OF TENOVIL (RHUIL-10) IN CLINICALLY STABLE CYSTIC FIBROSIS SUBJECTS; PROTOCOL #SP9901 07-Apr-00 THE INCIDENCE OF OSTEOPOROSIS IN PEDIATRIC BONE MARROW TRANSPLANT PATIENTS 13-Apr-00 RECOMBINANT HUMAN GROWTH HORMONE IN PEDIATRIC DIALYSIS PATIENTS 14-Apr-00 ABT-378/R (ABT-378/RITONAVIR) EARLY ACCESS PROGRAM 14-Apr-00 PREVENTION OF CHRONIC ASTHMA IN YOUNG CHILDREN 18-Apr-00 MOLECULAR MECHANISMS IN ACANTHOSIS NIGRICANS 19-Apr-00 CCG-B971 MOLECULAR BIOLOGY OF PEDIATRIC BRAIN TUMORS 21-Apr-00 THE SAFETY, VIRAL KINETICS AND PHARMACOKINETICS OF PEGASYS AFTER MULTIPLE DOSES IN YOUNG CHILDREN WITH CHRONIC HEPATITIS C INFECTION 24-Apr-00 SPECIFIC CELL-MEDIATED IMMUNITY IN HIV-INFECTED CHILDREN

14 Dr. Elizabeth Ann Esterl, RN October 10, 2017

24-Apr-00 CHROMOSOME 22G DELETION TESTING: INVESTIGATION OF CLINICAL PREDICTIVE FACTORS. 27-Apr-00 DIAGNOSTIC CRITERIA FOR URINARY TRACT INFECTIONS IN THOSE CHILDREN REFERRED FOR URINARY TRACT IMAGING STUDIES 28-Apr-00 A 12 MONTH STUDY TO ASSESS THE SAFETY AND EFFICACY OF MERIDIA (SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE) 10 AND 15 MG. IN OBESE ADOLESCENTS 01-May-00 PACTG 326: A PHASE I/II STUDY TO EVALUATE THE SAFETY AND IMMUNOGENICITY OF ALVAC HIV VACCINES ALONE AND WITH AIDSVAX B/B IN CHILDREN BORN TO HIV-INFECTED MOTHERS (VERSION 4.0) 02-May-00 EVALUATION OF THE EFFICACY, SAFETY, TOLERANCE AND PHARMACOKINETICS OF MEROPENEM FOR THE TREATMENT OF ACUTE PULMONARY EXACERBATIONS IN PATIENTS WITH CYSTIC FIBROSIS (#3591 US/0019). 03-May-00 MANOAMINE OXIDASE (MAO) IN ADOLESCENTS: RELATIONSHIP TO ALCOHOL MISUSE AND TO BEHAVIORAL PREDICTORS OF RISK FOR ALCOHOLISM 04-May-00 ROLE OF BACTERIAL SUPERANTIGENS IN KAWASAKI SYNDROME 04-May-00 AN OPEN-LABEL TRIAL EVALUATING THE SAFETY AND EFFICACY OF NOLVADEX (TAMOXIFEN CITRATE) IN THE TREATMENT OF MCCUNE- ALBRIGHT SYNDROME 08-May-00 C-AMP STIMULATED SWEAT RATE IN CYSTIC FIBROSIS 12-May-00 AUTOLOGOUS FRESH WHOLE BLOOD AND COAGULATION FOLLOWING CARDIOPULMONARY BYPASS IN INFANTS 12-May-00 PROPHYLAXIS OF EARLY ADRENAL INSUFFICIENCY TO PREVENT CHRONIC LUNG DISEASE 15-May-00 DIETARY SUPPLEMENTATION AND NUTRITIONAL STATUS IN CHILDREN WITH SICKLE CELL DISEASE 19-May-00 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL TO ASSESS THE SAFETY AND EFFICACY OF ANASTROZOLE (ZD1033, ARMIDEX) VERSUS PLACEBO FOR THE TREATMENT OF GYNECOMASTIA IN PUBERTAL BOYS 19-May-00 EFFECT OF INSULIN SENSITIVITY ON 24-H TOTAL AND DIETARY FAT OXIDATION IN NON-OBESE SUBJECTS 22-May-00 A PILOT STUDY OF PERIPHERAL BLOOD STEM CELL TRANSPLANTATION FOLLOWING PREPARATIVE THERAPY CONSISTING OF CYCLOPHOSPHAMIDE, BCNU, AND ETOPOSIDE FOR CHILDREN WITH RELASPED OR PRIMARILY REFRACTORY HODGKIN'S AND NON-HODGKIN'S LYMPHOMA (A5962) 22-May-00 MEDICAL AND FINANCIAL OUTCOMES USING TELEMEDICINE FOR DIAGNOSIS OF NEONATAL CONGENITAL HEART DISEASE 23-May-00 PROPHYLACTIC USE OF PRIMACOR IN PATIENTS AT HIGH RISK OF DEVELOPING LOW CARDIAC OUTPUT SYNDROME FOLLOWING CARDIAC SURGERY 30-May-00 FLUDARABINE AND LOW DOSE TOTAL BODY IRRADIATION

15 Dr. Elizabeth Ann Esterl, RN October 10, 2017

FOLLOWED BY UNRELATED CORD BLOOD TRANSPLANTATION FOR PATIENTS WITH HIGH RISK MALIGNANCIES 30-May-00 AN OPEN LABEL RANDOMIZED TRIAL WITH TOBRAMYCIN SOLUTION FOR INHALATION (TOBI) IN CYSTIC FIBROSIS PATIENTS WITH MILD LUNG DISEASE 02-Jun-00 A DOSE-RESPONSE STUDY OF THE EFFICACY, SAFETY AND PHARMACOKINETICS OF AMIODARONE AQUEOUS I.V. INJECTION IN PEDIATRIC PATIENTS NEONATAL TO SIXTEEN YEARS OF AGE WITH CLINICAL ARRHTHMIAS 05-Jun-00 PROGRAM EVALUATION FOR NEURO-ONCOLOGY TERMINAL CARE PROTOCOL 06-Jun-00 TREATMENT OF CHILDREN WITH DOWN SYNDROME AND ACUTE MYELOID LEUKEMIA, MYELODYSPLASTIC SYNDROME, OR TRANSIENT MYELOPROLIFERATIVE DISORDER CCG-A2971 08-Jun-00 MONITORING THORACIC GAS VOLUME USING RESPIRATORY INDUCTIVE PLETHYSMOGRAPHY 13-Jun-00 EVALUATION OF COMPASSIONATE USE (SINGLE PATIENT) OF THE CARDIOSEAL DEVICE SEPTAL OCCLUSION SYSTEM (SHUYLER LEAN) 14-Jun-00 CCG 99702: TREATMENT OF HIGH RISK MEDULLOBLASTOMA AND SUPRATENTORIAL PNETS WITH CONVENTIONAL RADIOTHERAPY AND INTENSIVE CONSOLIDATION CHEMOTHERAPY WITH PERIPHERAL BLOOD PROGENITOR CELL (PBSC) SUPPORT, A CCG LIMITED INSTITUTION STUDY 15-Jun-00 IMPROVING PROTEIN BALANCE IN POSTOPERATIVE NEONATE USING IV AMINO ACIDS 15-Jun-00 TREATMENT OF INSULIN RESISTANT ADOLESCENTS WITH METFORMIN 19-Jun-00 A COMPARISON OF PREDNISONE AND DEFLAZACORT'S EFFECT ON FUNCTIONAL SKILLS IN DUCHENNE MUSCULAR DYSTROPHY 19-Jun-00 DOES TWINNING INFLUENCE THE RELIABILITY OF THE THYROID NBN SCREENING TEST 20-Jun-00 A NATURAL HISTORY STUDY OF NEONATES WITH ENTROVIRAL SEPSIS SYNDROME 22-Jun-00 PEDIATRIC VEIN OCCLUSION 23-Jun-00 CONTINUED EVALUATION OF THE PERFORMANCE OF THE CARDIOSEAL STARFLEX SEPTAL OCCLUSION SYSTEM IN PATIENT WITH SECUNDUM ATRIAL SEPTAL DEFECT (ASD) 26-Jun-00 "SURFING THE WEB FOR GENETIC INFORMATION: PATIENT UTILIZATION OF PERCEPTIONS OF AND RELIANCE ON THE WWW AS AN INFORMATIONAL SOURCE IN THE GENERAL GENETICS SETTING 27-Jun-00 PACTG 402, VERSION 2.0: PHASE I/II OF SUBCUTANEOUS IL-2 WITH HIGHLY ACTIVE ANTIRETROVIRAL THERAPY IN HIV-INFECTED CHILDREN WITH IMMUNOSUPRESSION 27-Jun-00 CCG-09714: A PHASE II STUDY OF ORAL TOPOTECAN IN CHILDREN WITH RELAPSED ACUTE LEUKEMIA 28-Jun-00 A PHASE I-II LIMITED PILOT STUDY OF INTENSIVE CHEMOTHERAPY

16 Dr. Elizabeth Ann Esterl, RN October 10, 2017

WITH PERPHERAL BLOOD PROGENITOR CELL (PBSC) SUPPORT FOR INFANTS WITH MALIGNANT BRAIN TUMORS 28-Jun-00 CLINICAL PERFORMANCE MEASURE FOR PEDIATRIC BRAIN INJURY 29-Jun-00 A PHASE II MUTICENTER STUDY OF GRANULOCYTE-COLONY STIMULATING FACTOR (G-CSF)/DEXAMETHASONE MOBILIZED GRANULOCYTE TRANSFUSIONS FOR TREATMENT OF SERIOUS FUNGAL AND BACTERIAL INFECTIONS IN NEUTROPENIC PATIENTS AFTER CHEMOTHERAPY OR HEMATOPOIETIC TRANSPLANTATION 29-Jun-00 PREDICTIVE FACTORS FOR CEREBRAL EDEMA COMPLICATING DIABETIC KETOACIDOSIS IN CHILDREN 06-Jul-00 A PROSPECTIVE STUDY TO EVALUATE THE TESTING OF PLASMA POOLS FROM VOLUNTARY BLOOD DONATIONS FOR THE PRESENCE OF HIV-1 (HIV) RNA 06-Jul-00 A PROSPECTIVE STUDY TO EVALUATE THE TESTING OF PLASMA POOLS FROM VOLUNTARY BLOOD DONATIONS FOR THE PRESENCE OF HCV RNA 06-Jul-00 NM16189 A DOUBLE-BLIND, PLACEBO-CONTROLLED, 52-WEEK, STUDY OF THE EFFICACY AND TOLERABILITY OF XENICAL (ORLISTAT) IN THE WEIGHT MANAGEMENT OF OBESE PEDIATRIC PATIENTS 10-Jul-00 PERPETRATORS OF ABUSIVE FRACTURES 11-Jul-00 COMPARISON OF FENTANYL AND REMIFENTANIL FOR TRACK PEDIATRIC CARDIAC ANESTHESIA 11-Jul-00 COMPARISON OF FENTANYL AND REMIFENTANIL FOR FAST TRACK PEDIATRIC CARDIAC ANESTHESIA 14-Jul-00 COMPARISON OF IV VS IM KETAMINE FOR SEDATION IN A PEDIATRIC EMERGENCY DEPARTMENT 18-Jul-00 A PROSPECTIVE, OPEN-LABEL, NON-RANDOMIZED, NATURALISTIC, LONG- TERM SAFETY SURVEILLANCE, OBSERVATIONAL STUDY OF CIPROFLOXACIN (EITHER AS ORAL SUSPENSION, ORAL TABLETS, OR SEQUENTIAL IV - ORAL THERAPY OR PURELY IV THERAPY) IN THE TREATMENT OF PEDIATRIC PATIENTS WITH A VARIETY OF INFECTIOUS DIAGNOSES 20-Jul-00 RISK FACTORS FOR RSV CR1 HOSPITALIZATION 26-Jul-00 CLOSURE OF ATRIAL SEPTAL DEFECTS WITH THE AMPLATZER SEPTAL OCCLUDER (CONTINUED ACCESS) 27-Jul-00 ACTG 381(VERSION 3.0)-ESTABLISHMENT AND MAINTENANCE OF LONG TERM UNDECTABLE PLASMA HIV-1 RNA: CORRELATION WITH IMMUNOLOGIC RECONSTITUTION AND VIRAL DYNAMICS 31-Jul-00 ALTERNATE DAY STEROIDS VS FISH OILS VS PLACEBO IN CHILDREN WITH IGA NEPHROPATHY 31-Jul-00 EVALUATION OF THE PHARMACOKINETICS AND TOLERANCE OF ESCALATING DOSES OF ORAL PENTOXIFYLINE IN CHILDREN WITH ACUTE KAWASAKI DISEASE (10080, 3/24/99) 31-Jul-00 POST MARKETING SURVEY 31-Jul-00 ACTG 366 - A PHASE I/II MASTER PROTOCOL OF NOVEL

17 Dr. Elizabeth Ann Esterl, RN October 10, 2017

ANTIRETROVIAL COMBINATION THERAPIES IN ANTIRETROVIRAL EXPERIENCED CHILDREN WITH RAPIDLY PROGRESSING OR ADVANCED HIV DISEASE(RAD) VERSION 1.0 RAD-1 A PHASE I/II ANTIRETROVIRAL MANAGEMENT ALGORITHM FOR PEDIATRIC SUBJECTS OF FOUR-DRUG COMBINATION THERAPIES BASED ON PRIOR ANTIRETROVIRAL EXPERIENCE 31-Jul-00 VERSION 2.0 ACTG 367-MEDICAL CHART ABSTRACTION OF HIV- INFECTED PREGNANT WOMEN AND THEIR INFANTS RECEIVING CARE OR CONSULTATION AT STUDY SITES 02-Aug-00 A DOUBLE-BLIND, RANDOMIZED DOSE RESPONSE STUDY OF LISINOPRIL IN CHILDREN WITH HYPERTENSION 02-Aug-00 A MULTICENTER, UNCONTROLLED, OPEN STUDY IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION, TRANSITIONING FROM CHRONIC INTRAVENOUS FLOLAN THERAPY TO CHRONIC SUBCUTANEOUS UNIPROST 03-Aug-00 COMPARISON OF THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF 3 CONSISTENCY LOTS OF FROZEN MEASLES, MUMPS, RUBELLA AND VARICELLA (MMRV) IN HEALTHY CHILDREN 04-Aug-00 A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED SAFETY AND EFFICACY TRIAL OF SUSPENSION FORMULATION OF PLECONARIL IN THE TREATMENT OF VIRAL RESPIRATORY INFECTION IN CHILDREN AGE 2 TO 12 YEARS 09-Aug-00 (CCG-B973) A GROUP WIDE PROTOCOL FOR COLLECTING AND/OR BANKING NEUROBLASTOMA TUMOR SPECIMENS 10-Aug-00 IL-12 ABD IFN GAMMA PRODUCTION IN CHILDREN RECEIVING PEGYLATED INTERFERON (PEG) THERAPY FOR CHRONIC HEPATITIS 15-Aug-00 VALIDATION OF CLINICAL DECISION RULES FOR OBTAINING KNEE RADIOGRAPHS IN CHILDREN WITH ACUTE KNEE INJURIES 15-Aug-00 THE USE OF HUMAN WBC CONCENTRATED FROM RINSE-BACK OF APHERESIS PRODUCTS OBTAINED FROM BELLE BONFILS BLOOD CENTER 15-Aug-00 ENERGY EXPENDITURE IN NEONATES WITH HYPOXIC-ISCHEMIC ENCEPHALOPATHY 16-Aug-00 PHASE 1/PHASE 2 TRIAL OF ANTIOXIDANT THERAPY IN BILIARY ATRESIA 16-Aug-00 CCG 5941 A PILOT STUDY FOR THE TREATMENT OF NEWLY DIAGNOSED DISSEMINATED ANAPLASTIC LARGE CELL KI-1 AND T- LARGE CELL LYMPHOMA 18-Aug-00 ASSESSING BURN SURVIVOR'S SOCIAL EXPERIENCE AND IT'S IMPACT ON BODY IMAGE SATISFACTION 18-Aug-00 TWO-WEEK RANDOMIZED CROSSOVER AND PHARMACODYNAMIC MULTICENTER STUDY COMPARING CONVENTIONAL NEEDLE INJECTION OF GH SUBCUTANEOUSLY VERSES SUBCUTANEOUS INJECTION OF GH USING A NEEDLE-FREE INJECTOR 18-Aug-00 SIX MONTH PHARMACODYNAMIC MULTICENTER STUDY USING SUBCUTANEOUS SAIZEN IN A NEEDLE-FREE JET INJECTOR FOR CHILDREN WITH GROWTH HORMONE DEFICIENCY

18 Dr. Elizabeth Ann Esterl, RN October 10, 2017

18-Aug-00 SIX MONTH MULTICENTER STUDY USING SUBCUTANEOUS SAIZEN IN A NEEDLE-FREE JET INJECTOR FOR CHILDREN REQUIRING LONG TERM GROWTH HORMONE TREATMENT 24-Aug-00 ALLOGENIC BONE MARROW TRANSPLANTATION/PBSC TRANSPLANTATION FOR REFRACTORY HEMATOLOGIC MALIGNANCY OR HEMATOPOIETIC FAILURE 24-Aug-00 MEASUREMENT OF BONE MINERAL CONTENT USING DUAL X-RAY ABSORPTIOMETRY (DEXA) IN INFANTS AND CHILDREN WITH UNEXPLAINED FRACTURES 25-Aug-00 COMPARISON OF BODY COMPOSITION ASSESSMENT BY SKINFOLD AND DEXA IN PATIENTS WITH ANOREXIA NERVOSA 28-Aug-00 MOLECULAR ANALYSIS OF SARCOMA 29-Aug-00 PROTOCOL TO EVALUATE USE OF INTRAVENOUS FLUIDS AND ELECTROLYTE LEVELS AFTER CRANIOTOMY FOR BRAIN TUMORS 29-Aug-00 THE FORGOTTEN BOOSTER-AGE CHILD: PARENTAL ATTITUDES, KNOWLEDGE, AND REPORTED BEHAVIORS ABOUT CHILD PASSENGER SAFETY PRACTICES 30-Aug-00 THE EFFECTIVENESS OF THE FULLER INFANT ASSESSMENT TOOL FOR TEACHING NOVICE NURSES TO ASSESS AND MANAGE INFANT PAIN: A PILOT STUDY 30-Aug-00 FUNCTIONAL PROTEOMICS OF HUMAN EXOCYTIC ORGANELLES 30-Aug-00 NEEDS ASSESSMENT SURVEY IN BIOETHICS AT TCH 01-Sep-00 JUNGLEMOBILE: A MOBILE INJURY PREVENTION PROJECT FOR CHILDREN 06-Sep-00 PACTG 1010-EFFECT OF ANTIRETROVIRAL THERAPY ON BODY COMPOSITION IN HIV-INFECTED CHILDREN (VERSION 1) 12-Sep-00 PHENOTYPE AND ETIOLOGY OF PALLISTER-HALL SYNDROME 12-Sep-00 THE EFFECT OF FLUTICASONE PROPRIONATE ON GROWTH AND ADRENAL FUNCTION 22-Sep-00 PREDICTORS OF RESPONSE TO RECALL FOR IMMUNIZATION WITH A NEW VACCINE 29-Sep-00 POST REDUCTION MANAGEMENT OF INTUSSUSCEPTION: HOW LONG TO OBSERVE FOR RECURRENCE? 02-Oct-00 COLORADO SHILD WELFARE CHILDREN EXPERIENCING PARENTAL INCARCERATION: CHARACTERISTICS, NEED & HEALTH CARE UTILIZATION 11-Oct-00 STUDY OF THE SAFETY AND EFFECTIVENESS OF THE MENTOR SALINE-FILLED TESTICULAR PROSTHESIS AND ADJUNCT STUDY PROTOCOL FOR THE MENTOR SALINE-FILLED TESTICULAR PROSTHESIS 11-Oct-00 ADJUNCT STUDY PROTOCOL FOR THE MENTOR SALINE-FILLED TESTICULAR PROSTHESIS 11-Oct-00 A COMPARATIVE STUDY OF NEWLY HIRED GRADUATE NURSES' APPLICATION OF EVIDENCE-BASED PRACTICE: A PILOT STUDY 12-Oct-00 GAIT DISTURBANCE IN CHILDREN WITH OTITIS MEDIA

19 Dr. Elizabeth Ann Esterl, RN October 10, 2017

16-Oct-00 CCG-09705: A PHASE II STUDY OF NAVELBINE (VINORELBINE) IN CHILDREN WITH RECURRENT OR REFRACTORY MALIGNANCIES 16-Oct-00 EVALUATION OF HEMOPHILIC CHILDREN WITH DUAL X-RAY ABSORPTOMETRY (DEXA) 17-Oct-00 CCG-P9673 A PHASE II STUDY OF COMPOUND 506U78 IN PATIENTS WITH REFRACTORY T-CELL MALIGNANCIES - A POG/CCG INTERGROUP STUDY 20-Oct-00 CCG-0962 PHASE II STUDY OF DOCETAXEL (TAXOTERE) (NSC #628503) IN CHILDREN WITH RECURRENT SOLID TUMORS 20-Oct-00 CCG-B972: IMMUNE STATUS AND ACTIVATION IN CHILDREN PATICIPATING IN CCG-2961 (PREVIOUSLY 96-597C) 25-Oct-00 A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY TO ASSESS THE EFFECTS OF RO 47-0203 (BOSENTAN) ON EXERCISE CAPACITY IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION; PROTOCOL NUMBER AC-052-352 25-Oct-00 A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PARALLEL GROUP, PLACEBO-CONTROLLED, 12-WEEK STUDY OF FLUTICASONE PROPIONATE 44 MCG BID AND 88 MCG BID DELIVERED VIA CFC MDI AND A VALVED HOLDING CHAMBER WITH FACEMASK IN SUBJECTS WITH ASTHMA AGE 24 MONTHS TO 47 MONTHS. 25-Oct-00 A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PARALLEL GROUP, PLACEBO-CONTROLLED, 12-WEEK STUDY OF FLUTICASONE PROPIONATE 44 MCG BID AND 88 MCG BID DELIVERED VIA CFC MDI AND A VALVED HOLDING CHAMBER WITH FACEMASK IN SUBJECTS WITH ASTHMA AGE 6 MONTHS TO 23 MONTHS 25-Oct-00 TRANSCUTANEOUS CARBOXY HEMOGLOBIN (COHB) MONITORING FOR ASSESSMENT OF ENVIRONMENTAL CARBON MONOXIDE EXPOSURE IN CHILDREN HAVING SURGERY 27-Oct-00 CCG-4941: NATIONAL WILM'S TUMOR STUDY-5: THERAPEUTIC TRIAL AND BIOLOGY STUDY 27-Oct-00 SPIRITUALITY IN YOUNG ADULT BURN SURVIVORS 27-Oct-00 A SAFETY AND EFFICACY STUDY OF TWO DOSAGE-LEVELS OF PULMICORT RESPULES (BUDESONIDE INHALATION SUSPENSION, 0.5 OR 1.0 MG/DAY) VERSUS PLACEBO IN INFANTS BETWEEN THE AGES OF SIX AND TWELVE MONTHS WITH MILD TO MODERATE ASTHMA (STUDY NUMBER SD-004-0732) 30-Oct-00 A PROSPECTIVE, RANDOMIZED TRIAL OF SANDOSTATIN (OCTREOTIDE ACETATE) FOR THE TREATMENT OF PEDIATRIC HYPOTHALAMIC OBESITY 02-Nov-00 FIRST TIME AFEBRILE PEDIATRIC SEIZURES: USEFULNESS OF EMERGENT HEAD CT IN EVALUATION AND MANAGEMENT 02-Nov-00 PEDIATRIC RAPID SEQUENCE INTUBATION 09-Nov-00 FIBRINOLYSIS AND POLYCYSTIC OVARY SYNDROME 10-Nov-00 TARGETED SURVEILLANCE OF STREPTOCOCCUS PNEUMONIAE; PROTOCOL 1351-SKB-00ED 10-Nov-00 COMPARISON OF THE EFFICACY AND SAFETY OF SEDATION DRUGS

20 Dr. Elizabeth Ann Esterl, RN October 10, 2017

USED IN A PEDIATRIC EMERGENCY DEPARTMENT 14-Nov-00 GUIDED BREATHING AND IMAGERY: A PREFERENCE STUDY IN CHILDREN 20-Nov-00 USE OF AN IMMUNIZATION REGISTRY TO RECALL CHILDREN WITH ASTHMA FOR INFLUENZA VACCINATION 20-Nov-00 CCG-B942: DETECTION OF MINIMAL RESIDUE DISEASE IN CHILDREN RECEIVING THERAPY FOR AML OR MDS (PREVIOUSLY 96-597B) 20-Nov-00 EFFECTIVENESS OF PNEUMOCOCCAL CONJUGATE VACCINE IN CHILDREN 27-Nov-00 CCG-P9462: RANDOMIZED TREATMENT OF REFRACTORY NEUROBLASTOMA WITH TOPOTECAN REGIMENS, FOLLOWING DEFEROXAMINE (POG ONLY) IN AN INVESTIGATIONAL WINDOW, A POG/CCG PHASE II INTERGROUP STUDY 27-Nov-00 AN EXPLORATORY STUDY OF A WORK ENVIRONMENT MODEL WITHIN AN ACUTE CARE SETTING 27-Nov-00 EVALUATION OF LEVELS OF CANCER PROCOAGULANT IN PEDIATRIC PATIENTS WITH SARCOMAS AND CNS TUMORS AT DIAGNOSIS, REMISSION, AND RELAPSE 30-Nov-00 SAFETY AND PHARMACOKINETIC STUDY OF ZONISAMIDE (ZONEGRAN) ADMINISTERED TO CHILDREN WITH EPILEPSY 30-Nov-00 OPEN LABEL, EXTENDED TREATMENT SAFETY STUDY OF ZONISAMIDE (ZONEGRAN) ADMINISTERED TO CHILDREN WITH EPILEPSY; PROTOCOL NUMBER AN46046-226 01-Dec-00 CARDIAC DIASTOLIC FUNCTION: A NEW MEASUREMENT TECHNIQUE 04-Dec-00 CCG-4942: NATIONAL WILM'S TUMOR STUDY-5: RELAPSED PROTOCOL 11-Dec-00 OUTCOMES SURVEY OF SYNAGIS PROPHYLAXIS 13-Dec-00 A MULTI-CENTER, OPEN-LABEL, SINGLE-DOSE STUDY TO EVALUATE THE PLASMA CONCENTRATION-TIME PROFILE AND TOLERABILITY OF A SINGLE 3.5 MG INTRAVENOUS DOSE OF MONTELUKAST (SINGULAIR) IN CHILDREN AGED 2 TO 14 YEARS WITH ASTHMA; PROTOCOL NO: 215-02 18-Dec-00 CCG-4941L NATIONAL WILMS TUMOR LATE EFFECTS STUDY 18-Dec-00 A SAFETY, TOLERABILITY AND EFFICACY STUDY OF LEVALBUTEROL AND RACEMIC ALBUTEROL IN PEDIATRIC SUBJECTS BIRTH TO 48 MONTHS OLD WITH REACTIVE AIRWAY DISEASE IN AN ACUTE SETTING; PROTOCOL NUMBER 051-033 21-Dec-00 IMMUNOLOGIC RECONSTITUTION FOLLOWING HIGH DOSE CHEMOTHERAPY AND AUTOLOGOUS PERIPHERAL BLOOD PROGENITOR CELL TRANSPLANTATION (#98-383) 26-Dec-00 A PROTOCOL TO COLLECT AND EVALUATE TISSUE SAMPLES IN SUBJECTS WITH CYSTIC FIBROSIS, CARRIERS OF CYSTIC FIRBROSIS, AND HEALTHY NON-CARRIERS OF CYSTIC FIBROSIS 27-Dec-00 USE OF VIDEO TECHNOLOGY TO BRING THE PATIENT TO THE TEACHING CONFERENCE

21 Dr. Elizabeth Ann Esterl, RN October 10, 2017

28-Dec-00 T20-301/NV16504 VERSION C: A PHASE III OPEN-LABEL, RANDOMIZED ACTIVE-CONTROLLED STUDY ASSESSING THE EFFICACY AND SAFETY OF T-20/RO 29-9800 (HIV-1 FUSION INHIBITOR) IN COMBINATION WITH AN OPTIMIZED BACKGROUND REGIMEN, VERSUS OPTIMIZED BACKGROUND REGIMEN ALONE, IN PATIENTS WITH PRIOR EXPERIENCE AND/OR PRIOR DOCUMENTED RESISTANCE TO EACH OF THE THREE APPROVED CLASSES OF ANTIRETROVIRALS (NUCLEOSIDE REVERSE TRANSCRIPTASE, NON-NUCLEOSIDE REVERSE TRANSCRIPTASE AND PROTEASE INHIBITORS) 05-Jan-01 VALIDATION OF SPUTUM INDUCTION AS AN OUTCOME MEASURE FOR LOWER AIRWAY SAMPLING IN PATIENTS WITH CYSTIC FIBROSIS (CF) 05-Jan-01 REGULATION OF HUMAN ALVEOLAR MACROPHAGE CHEMOKINE PRODUCTION 05-Jan-01 RELATIONSHIP BETWEEN MOLECULAR STATUS AND COGNITIVE ABILITY IN FEMALES WITH FRAGILE X 05-Jan-01 PROSPECTIVE ASSESSMENT AFTER PEDIATRIC CARDIAC ABLATION 09-Jan-01 A PROSPECTIVE, DOUBLE-BLIND, RANDOMIZED, ACTIVELY CONTROLLED, PARALLEL GROUP STUDY ON THE EFFICACY AND SAFETY OF LIQUID IMMUNE GLOBULIN INTRAVENOUS (HUMAN) CE1160 10%, COMPARED TO IMMUNE GLOBULIN INTRAVENOUS (HUMAN) GAMIMUNE N, 10% IN SUBJECTS WITH IMMUNE THROMBOCYTOPENIC PURPURA (ITP) AMENDED AUGUST 16, 2000 09-Jan-01 MOVING TOWARD EVIDENCE-BASED DEVELOPMENTAL POSITIONING 09-Jan-01 AN OPEN-LABEL SAFETY, EFFICACY AND TOLERABILITY STUDY OF CARBATROL IN CHILDREN WITH EPILEPSY; PROTOCOL NUMBER 101.404 10-Jan-01 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER, MULTIPLE DOSE, SEQUENTIAL DOSE ESCALATION STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF NBI-6024 IN ADULT AND ADOLESCENT PATIENTS WITH INSULIN-DEPENDENT TYPE-1 DIABETES MELLITUS. AMENDMENT 1 VERSION DATE: NOV. 27,2000. FINAL VERSION DATE: SEPT. 21, 2000 11-Jan-01 THE BURDEN OF ILLNESS OF RESPIRATORY SYNCYTIAL VIRUS (RVS): A STUDY OF CHILD AND FAMILY DISTRESS AND ADJUSTMENT DURING HOSPITALIZATION AND RECOVERY 12-Jan-01 CCG-AE23 EPIDEMIOLOGY OF DOWN SYNDROME-LEUKEMIA AND DOWN SYNDROME 17-Jan-01 RESEARCH PROTOCOL C0015-40: A PHASE 2, RANDOMIZED, DOUBLE- MASKED, PLACEBO-CONTROLLED, MULTI-CENTER STUDY OF INTRANASALLY ADMINISTRATED RFI-641 FOR SECONDARY PREVENTION AND THERAPEUTIC TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS INFECTION (RSV) IN ADULTS IN HOUSEHOLDS 19-Jan-01 AN OPEN-LABEL, NON-COMPARATIVE PROTOCOL FOR THE EMERGENCY USE OF VORICONAZOLE (UK 109,496) IN PATIENTS WITH LIFE-THREATENING, INVASIVE MYCOSES WHO ARE FAILING ON CURRENTLY AVAILABLE ANITFUNGAL AGENTS

22 Dr. Elizabeth Ann Esterl, RN October 10, 2017

22-Jan-01 AN OBSERVATIONAL STUDY OF THE EPIDEMILOGY AND NATURAL HISTORY OF ASTHMA: OUTCOMES AND TREATMENT REGIMENS (Q2196N) 24-Jan-01 ROLE OF RIGHT AND LEFT VENTRICULAR ANNULAR MOTION IN RIGHT VENTRICULAR FUNCTION 25-Jan-01 ACUTE LIVER FAILURE STUDY 26-Jan-01 INFLAMMATORY AND VASOACTIVE MEDIATORS IN SEVERE RSV DISEASE 29-Jan-01 PILOT STUDY OF MYCOPHENOLATE MOFETIL (MMF) IN CHILDREN WITH STEROID-DEPENDENT NEPHROTIC SYNDROME (SDNS) A STUDY BY THE SOUTHWEST PEDIATRIC NEPHROLOGY STUDY GROUP (SPNSG) 01-Feb-01 THE USE OF DUAL ENERGY ABSORPTIOMETRY TO DETERMINE BONE MINERAL DENSITY IN CHILDREN WITH SPINA BIFIDA 02-Feb-01 A PILOT STUDY OF FISH OIL (OMEGA-3-POLYUNSATURATED FATTY ACIDS) FOR TREATMENT OF HYPERLIPIDEMIA IN CHILDREN WITH CHRONIC GLOMERULAR DISEASE 05-Feb-01 INVESTIGATION OF GROWTH HORMONE DEFICIENCY IN PATIENT WITH ORGANIC ACIDEMIA AND SHORT STATURE 07-Feb-01 2ND OSOM ULTRA STREP A TEST VS. BACK-UP CULTURE FOR THE DIAGNOSIS OF STREPTOCOCCUS PYOGENES PHARYNGITIS 12-Feb-01 A PHASE I/II STUDY OF INTERFERON GAMMA-LB BY INHALATION FOR THE TREATMENT OF PATIENTS WITH CYSTIC FIBROSIS 14-Feb-01 THREE MONTH DOUBLE MASKED, ACTIVE TREATMENT CONTROLLED, MULTICENTER STUDY OF 2% DORZOLAMIDE T.I.D. AND OF TIMOLOL MALEATE IN GEL-FORMING SOLUTION Q.D. IN PEDIATRIC PATIENTS AGE <6 YEARS WITH ELEVATED INTRAOCULAR PRESSURE OR GLAUCOMA, MERCK PROTOCOL 100-05 16-Feb-01 A 12 WEEK DOUBLE-BLIND RANDOMIZED TRIAL, WITH A 12 WEEK OPEN-LABEL EXTENSION, TO INVESTIGATE THE EFFICACY AND SAFETY OF MELOXICAM ORAL SUSPENSION ADMINISTRATION ONCE DAILY AND NAPROXEN ORAL SUSPENSION ADMINISTERED TWICE DAILY IN CHILDREN WITH JUVENILE RHEUMATOID ARTHRITIS; PROTOCOL NUMBER: 107.235 16-Feb-01 SAFETY AND EFFICACY OF PENTAVALENT (G1, G2, G3, G4, P1) HUMAN-BOVINE REASSORTANT ROTAVIRUS VACCINE IN HEALTHY INFANTS (PROTOCOL 006-00) 23-Feb-01 AN OPEN, RANDOMIZED, MULTICENTER STUDY OF THE SAFETY, TOLERABILITY, ND IMMUNOGENICITY OF FROZEN MMRV GIVEN CONCOMITANTLY VERSUS NONCONCOMITANTLY WITH OTHER PEDIATRIC VACCINES IN HEALTHY CHILDREN 12 TO 15 MONTHS OF AGE PROTOCOL 013-02 14-Mar-01 PACTG P1024 EVALUATION OF THE IMMUNOGENICITY OF PNEUMOCOCCAL CONJUGATE VACCINE AND ROUTINE PEDIATRIC IMMUNIZATIONS IN HIV-INFECTED CHILDREN TREATED WITH HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART) 14-Mar-01 VENOUS ACCESS IN PEDIATRIC POST-RUPTURED APPENDECTOMY PATIENTS

23 Dr. Elizabeth Ann Esterl, RN October 10, 2017

14-Mar-01 CHARACTERISTICS AND ROLE FUNCTIONS OF ADVANCED PRACTICE NURSES 14-Mar-01 VALPROIC ACID RELATED PROTEIN C DEFICIENCY 15-Mar-01 AN EXPLORATION OF PARENTS' PATTERNS OF STRESS AND ANXIETY WITH THEIR PREOPERATIVE CHILDREN 16-Mar-01 LINEZOLID IV/PO VS VANCOMYCIN IV FOR THE TREATMENT OF RESISTANT GRAM-POSITIVE BACTERIAL INFECTIONS IN CHILDREN; PROTOCOL NUMBER M/1260/0082 19-Mar-01 MULTICENTER PIVOTAL STUDY OF THE HELEX SEPTAL OCCLUDER 19-Mar-01 TISSUE PLASMINOGEN ACTIVATOR (TPA) DOSE-FINDING IN CHILDREN WITH VENOUS THROMBOSIS 20-Mar-01 CLINICAL VERIFICATION OF A MODIFIED DIRECTIGEN RSV KIT 28-Mar-01 A DESCRIPTIVE STUDY OF SPIRITUALITY AMONG PARENTS AND GUARDIANS OF CHILDREN WITH BRAIN TUMORS, HEAD INJURIES AND SPINAL CORD INJURIES, THEIR NURSES AND CHAPLAINS 29-Mar-01 AIRWAY EPITHELIAL CELL GENOMICS AND PSEUDOMONAS AERUGINOSA INFECTION IN CYSTIC FIBROSIS PATIENTS 29-Mar-01 MODIFIERS OF EARLY PANCREATIC INJURY IN CYSTIC FIBROSIS 29-Mar-01 COMPARISON OF FASCIA ILIACA COMPARTMENT NERVE BLOCK TO TRADITIONAL ANALGESICS FOR FEMUR FRACTURES IN A PEDIATRIC EMERGENCY DEPARTMENT 30-Mar-01 EPIDEMIOLOGY, OUTCOMES, AND REASONS FOR LATE PRESENTATION IN CHILDREN DIAGNOSED WITH KAWASKI'S DISEASE 02-Apr-01 PHARMACOKINETICS AND TOLERABILITY OF TRACLEER (BOSENTAN) IN PEDIATRIC PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION: SINGLE AND MULTIPLE ORAL DOSES; PROTOCOL NUMBER AC-052-356. 02-Apr-01 A MULTICENTER, DOUBLE BLIND, RANDOMIZED TRIAL OF STEROID WITHDRAWAL IN SIMULECT, SIROLIMUS, AND CYCLOSPORINE OR TACROLIMUS TREATED PRIMARY TRANSPLANT RECIPIENTS, CONDUCTED BY THE NORTH AMERICAN PEDIATRIC RENAL TRANSPLANT COOPERATIVE STUDY (NAPRTCS) 04-Apr-01 A RANDOMIZED, INVESTIGATOR BLIND, MULTICENTER STUDY TO ASSESS THE EFFICACY OF ORAL AUGMENTIN ES TWICE DAILY FOR 10 DAYS VERSUS ORAL ZITHROMAX ONCE DAILY FOR 5 DAYS IN THE TREATMENT OF ACUTE OTITIS MEDIA IN INFANTS AND CHILDREN (PROTOCOL BRL-25000/611) 16-Apr-01 AN INTERNET FOCUSED DISCUSSION SURVEY ON THE USE OF AUDITORY SCANNING AS AN ACCESS METHOD FOR AUGMENTATIVE AND ALTERNATIVE COMMUNICATION SYSTEMS 17-Apr-01 DEVELOPMENT OF OPTICAL METHODS TO MEASURE BLOOD COAGULATION TIMES 19-Apr-01 SAFETY AND TOLERABILITY OF OXYBUTYNIN CHLORIDE (DITROPAN XL EXTENDED RELEASE TABLETS, DITROPAN TABLETS OR DITROPAN SYRUP) IN THE TREATMENT OF DETRUSOR HYPERREFLEXIA DUE TO NEUROGENIC CONDITIONS IN CHILDREN

24 Dr. Elizabeth Ann Esterl, RN October 10, 2017

AGED 6 TO 15 YEARS (INCLUDING AMENDMENT 1) 19-Apr-01 LIMB PAIN ASSOCIATED WITH AN UNDIAGNOSED HEMOGLOBINOPATHY 23-Apr-01 SAFETY AND EFFICACY OF HMR4396 FOR THE MANAGEMENT OF ANEMIA IN PEDIATRIC SUBJECTS WITH CHRONIC RENAL FAILURE (PREDIALYSIS, HEMODIALYSIS, PERITONEAL DIALYSIS); PROTOCOL NUMBER HMR4396A/3003 25-Apr-01 OPEN LABEL USE OF HUMAN IMMUNE GLOBULIN 02-May-01 A PHASE 1B/2A ASCENDING DOSE COHORT STUDY TO ASSESS THE SAFETY, TOLERABILITY, AND EFFECTS OF FIVE DOSE LEVELS OF INS37217 AND PLACEBO FOLLOWED BY FIVE DAYS TWICE DAILY TREATMENT WITH MAXIMUM TOLERATED DOSE ADMINISTERED BY INHALATION VIA THE PARI LC STAR NEBULIZER IN ADULT AND PEDIATRIC PATIENTS WITH CYSTIC FIBROSIS 02-May-01 CORRELATION OF OUTCOME MEASURES FOR POST-THROMBOTIC SYNDROME IN CHILDREN WITH VENOUS THROMBOSIS 09-May-01 IMMUNOLOGIC ASPECTS OF THE PATHOGENESIS OF CHRONIC SINUSITIS IN CHILDREN 09-May-01 MECHANISMS OF STEROID RESISTANT ASTHMA 09-May-01 RESPIRATORY SYNCITIAL VIRUS INFECTION: INCIDENCE IN YOUNG INFANTS 13-May-01 LONG TERM FOLLOW-UP PROTOCOL TO ASSESS PEDIATRIC SUBJECTS AFTER COMPLETING 24 WEEKS OF FOLLOW-UP IN SPRI CLINICAL TRIAL FOR CHRONIC HEPATITIS C 14-May-01 LINEZOLID INJECTION: SINGLE DOSE PHARMACOKINETIC ASSESSMENT IN PEDIATRIC PATIENTS FOLLOWING AN INTRAVENOUS INFUSION; PROTOCOL NUMBER 766-INF-0026-111. 15-May-01 DEVELOPMENT OF A HOSPITAL BASED HOME PROGRAM FOR THE USE OF INHALED NITRIC OXIDE IN THE CHRONIC MANAGEMENT OF SEVERE CARDIOPULMONARY DISEASES 15-May-01 CHROMOGENIC IX ASSAY 24-May-01 ATTITUDES TOWARDS SMOKING AND SMOKING CESSATION IN ADOLESCENT PATIENTS WITH DIABETES AND WITHOUT DIABETES 01-Jun-01 HANDWASHING BEHAVIOR IN PRESCHOOL CHILDREN: OBSERVATIONS AND IMPLICATIONS IN ACCIDENTAL VS. ABUSIVE SCALD INJURY 07-Jun-01 DOSE-FINDING FOR LOW MOLECULAR WEIGHT HEPARIN (LMWH) IN CHILDREN WITH THROMBOSIS 08-Jun-01 DOSE-RANGING TRIAL UTILIZING A RECOMBINANT UROKINASE (ABT-120) IN THE TREATMENT OF OCCLUDED CENTRAL VENOUS CATHETERS PRIMARILY IN ONCOLOGY SUBJECTS, PROTOCOL NUMBER: M99-116 13-Jun-01 A RANDOMIZED, PLACEBO-CONTROLLED, TRIAL TO ASSESS SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF INFLUENZA VIRUS VACCINE, TRIVALENT, TYPES A & B, LIVE COLD-ADAPTED (FLUMIST) AND MEASLES, MUMPS, RUBELLA, (MMRII) AND VARICELLA (VARIX

25 Dr. Elizabeth Ann Esterl, RN October 10, 2017

AX) VACCINES ADMINISTERED CONCURRENTLY TO HEALTHY CHILDREN 15-Jun-01 SUPPORTIVE CARE NETWORK AT THE CHILDREN'S HOSPITAL 18-Jun-01 A MULTICENTER STUDY TO EVALUATE THE EFFICACY, SAFETY, AND PHARMACOKINETICS OF BREVIBLOC (ESMOLOL HYDROCHLORIDE) FOR THE TREATMENT OF HYPERTENSION IN INFANTS AND CHILDREN AFTER SURGICAL REPAIR OF COARCTATION OF THE AORTA; PROTOCOL NO.: 20,015-004 20-Jun-01 COMPARISON OF DISEASE SEVERITY AT TIME OF REFERRAL FOR CHILDREN WITH OBESITY AND FAILURE TO THRIVE 20-Jun-01 THE USE OF THE MINIMED CONTINUOUS GLUCOSE MONITORING SYSTEM IN THE MANAGEMENT OF GLYCOGEN STORAGE DISEASE, TYPE IA 27-Jun-01 PACTG P1006 - THE EFFECTS OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART) ON THE RECOVERY OF IMMUNE FUNCTION IN HIV - INFECTED CHILDREN. 28-Jun-01 RADIOGRAPHIC AND CLINICAL OUTCOME ASSESSMENT OF "SINGLE CURVES" IN ADOLESCENT IDIOPATHIC SCOLIOSIS: A PILOT STUDY PRELUDE TO A PROSPECTIVE INVESTIGATION. 29-Jun-01 P9962 A PHASE II STUDY OF INTRATHECAL TOPOTECAN IN PATIENTS WITH REFRACTORY MENINGEAL MALIGNANCIES 05-Jul-01 BISPECTRAL INDEX MONITORING IN SEDATED PATIENTS IN THE PEDIATRIC INTENSIVE CARE UNIT 05-Jul-01 HEMOPHILIA JOINT ATLAS 10-Jul-01 BRAIN TISSUE BANKING ACTIVITIES OF THE IMMUNOLOGY/NEURO- ONCOLOGY RESEARCH LABORATORY 13-Jul-01 PERSISTENT TACHYPNEA OF INFANCY: A RETOSPECTIVE REVIEW 16-Jul-01 A STUDY OF SEQUENTIAL HIGH DOSE CYCLOPHOSPHAMIDE AND HIGH DOSE CARBOPLATIN WITH PERIPHERAL STEM CELL RESCUE 23-Jul-01 EVALUATION OF PULMONARY FUNCTION TESTS FROM RAISED LUNG VOLUMES AS OUTCOME MEASURES FOR CLINICAL TRIALS IN INFANTS WITH CYSTIC FIBROSIS. 25-Jul-01 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED SAFETY AND EFFICACY STUDY OF SITAXSENTAN SODIUM TREATMENT IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION 25-Jul-01 AN EXTENSION STUDY TO EVALUATE THE LONG-TERM SAFETY AND PHARMACOKINETICS OF SITAXSENTAN SODIUM TREATMENT IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION 30-Jul-01 HHV-6 ASSOCIATED DISEASES OF THE CENTRAL NERVOUS SYSTEM IN IMMUNOCOMPETENT AND IMMUNOCOMPROMISED CHILDREN 01-Aug-01 INVESTIGATION OF THE FINDING OF CORONARY ARTERY PROMINENCE IN KAWASAKI DISEASE. 01-Aug-01 SUBTOTAL TONSILLAR ALBATION VS TRADITIONAL TONSILLECTOMY FOR MANAGEMENT OF OBSTRUCTIVE TONSILLAR HYPERTROPHY; PROTOCOL E1021

26 Dr. Elizabeth Ann Esterl, RN October 10, 2017

03-Aug-01 BISPECTRAL INDEX MONITORING DURING CONSCIOUS AND DEEP SEDATION 06-Aug-01 GENETIC MODIFIERS IN CYSTIC FIBROSIS LUNG DISEASE 08-Aug-01 EFFECT OF CAFFEINE ON ENERGY EXPENDITURE IN PREMATURE NEONATES 09-Aug-01 ANALYSIS OF PERPETRATORS' HISTORIES AND ADMISSIONS CONCERNING INFLICTED TRAUMATIC BRAIN INJURY IN CHILDREN. 09-Aug-01 PEDIATRIC ELECTROCARDIOGRAM (EKG) INTERPRETATION ACCURACY BY PEDIATRIC EMERGENCY MEDICINE (PEM) PHYSICIANS. 14-Aug-01 A PROSPECTIVE MULTINATIONAL, MULTICENTER, CLINICAL TRIAL OF THE SAFETY AND EFFICACY OF RECOMBINANT HUMAN ACID A- GLUCOSIDASE (RHGAA) IN CROSS-REACTING IMMUNOLOGIC MATERIAL-POSITIVE (CRIM(+)) PATIENTS WITH CLASSICAL INFANTILE POMPE DISEASE 16-Aug-01 A 6-MONTH OPEN LABEL, MULTI-NATIONAL, EFFECTIVENESS, AND SAFETY STUDY OF ELIDEL (PIMECROLIMUS) CREAM, 1% IN SUBJECTS WITH ATOPIC DERMATITIS; PROTOCOL NUMBER: CASM981C2405 17-Sep-01 EPIDEMIOLOGICAL STUDY OF THE NATURAL HISTORY OF FABRY DISEASE (AGAL 014-01) 12-Oct-01 INFLUENCE OF THE PROTONICS NEUROMUSCULAR SYSTEM ON KINEMATICS AND EMG OF PATIENTS WITH PATELLOFEMORAL PAIN SYNDROME 18-Oct-01 A MULTICENTER, RANDOMIZED STUDY TO DETERMINE THE PHARMACOKINETICS AND PHARMACODYNAMICS OF FENOLDOPAM MESYLATE IN PEDIATRIC SUBJECTS. 29-Oct-01 SURGICAL CORRECTION OF IDIOPATHIC SCOLIOSIS-ALGORITHM STUDY 01-Nov-01 FAMILY AND YOUTH SERVICES STUDY 09-Nov-01 A TWELVE WEEK, MULTICENTER, DOUBLE-MASKED, PARALLEL GROUP, PRIMARY THERAPY STUDY OF THE SAFETY AND EFFICACY OF BETOPTIC S 0.25% COMPARED TO TIMOLOL GEL FORMING SOLUTION 0.25% AND 0.57 % IN PEDIATRIC PATIENTS WITH GLAUCOMA OR OCULAR HYPERTENSION. 16-Nov-01 MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO- CONTROLLED STUDY OF THE SAFETY AND EFFICACY OF RECOMBINANT HUMAN A-GALACTOSIDASE A (R-HAGAL) ON PROGRESSION OF RENAL DISEASE AND SIGNIFICANT CLINICAL EVENTS IN PATIENTS WITH FABRY DISEASE 19-Nov-01 DEVELOPMENT OF A FINANCIALLY SELF-SUSTAINING CHILD SAFETY SEAT DISTRIBUTION PROGRAM 19-Nov-01 THE DETERMINATION OF THE HEALING PROCESS OF ANAL/GENITAL INJURIES IN CHILDREN AND ADOLESCENTS: A MULTI-CENTER RETROSPECTIVE STUDY 20-Nov-01 USE OF THE EMOTIONAL REACTIONS CHECKLIST WITH HOSPITALIZED CHILDREN AND ADOLESCENTS

27 Dr. Elizabeth Ann Esterl, RN October 10, 2017

26-Nov-01 A PHENOMENOLOGICAL APPROACH TO INPATIENT EXPERIENCES OF PEDIATRIC BURN AND TRAUMA PATIENTS IN A CRITICAL CARE UNIT 28-Nov-01 A SURVEY OF CHRONIC PAIN IN THE PEDIATRIC SPINAL CORD INJURY POPULATION 30-Nov-01 AN OPEN, NON-RANDOMIZED, MULTICENTER STUDY IN CHILDREN WITH VESICOURETERAL REFLUX GRADE II-IV RECEIVING ENDOSCOPIC CORRECTION WITH DEFLUX. 30-Nov-01 PACTG P1015: INTENSIFICATION OF HIV-SPECIFIC CD4 AND CD8 ACTIVITY BY CYCLING HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART) IN PEDIATRIC/ADOLESCENT PATIENTS WITH <50 HIV RNA COPIES/ML 30-Nov-01 DURATION OF ANTIMICROBIAL TREATMENT EFFECT FOLLOWING ADMINISTRATION OF TOBRAMYCIN FOR INHALATION (TOBI) IN YOUNG CHILDREN WITH CYSTIC FIBROSIS 05-Dec-01 CLINICAL CORRELATIONS OF SIROLIMUS CONCENTRATIONS IN BLOOD FROM LIVER AND KIDNEY TRANSPLANT PATIENTS 12-Dec-01 ADAPTATION OF THE PEDIATRIC TQPM INSTRUMENTS FOR AMBULATORY SURGERY PATIENTS 13-Dec-01 CHILD PASSENGER SAFETY: ASSESSING KNOWLEDGE OF HEALTH CARE PROVIDERS ON CURRENT RECOMMENDATIONS 20-Dec-01 CHART REVIEW OF PATIENTS WITH ABSENCE EPILEPSY 09-Jan-02 VERIFICATION OF A KIT (DIRECTIGEN LATERAL FLOW RSV TEST) FOR RAPID LABORATORY DETECTION OF RESPIRATORY SYNCYTIAL VIRUS INFECTIONS. 10-Jan-02 FABRY INTERNATIONAL RESEARCH EXCHANGE (F.I.R.E.) A REGISTRY OF FABRY DISEASE: A MULTICENTER, LONGITUDINAL OBSERVATIONAL STUDY 11-Jan-02 ESCHERICHIA COLI INFECTION STUDIES: VIRULENCE OF EXTRAINTESTINAL STRAINS 12-Jan-02 EVALUATION OF OVARIAN STEROIDOGENESIS IN A PATIENT WITH CONGENITAL LIPOID ADRENAL HYPERPLASIA 14-Jan-02 A COMPARISON OF NURSING PROFESSIONAL VALUES BETWEEN STUDENTS AND STAFF. 18-Jan-02 AN INVESTIGATION OF CAMPS FOR BURN INJURED CHILDREN: DEVELOPING A SOCIAL WORK MODEL OF PRACTICE AND EVALUATION "THE BURN CAMP PROJECT" 18-Jan-02 OPEN-LABEL, LONG-TERM SAFETY STUDY OF ZONISAMIDE (ZONEGRAN) ADMINISTERED TO CHILDREN WITH EPILEPSY 21-Jan-02 THE EFFECT OF DEHYDRATION ON THE QTC INTERVAL OF HEALTHY CHILDREN 28-Jan-02 GENETIC DETERMINANTS OF CHRONIC RHINOSINUSITIS IN CHILDREN 28-Jan-02 A RANDOMIZED PHASE 2 TRIAL OF GUIDED IMAGERY IN LYMPHOMA AND LEUKEMIA BONE MARROW TRANSPLANT PATIENTS 31-Jan-02 CYSTOVENTRICULAR SHUNTING: A TREATMENT OPTION FOR

28 Dr. Elizabeth Ann Esterl, RN October 10, 2017

INTRACRANIAL ARACHNOID CYSTS. 31-Jan-02 COMPARISON AND PREDICTABILITY OF MIDDLE AND ANTERIOR CEREBRAL ARTERY DOPPLER FLOW STUDIES IN ASPHYXIATED NEAR-TERM INFANTS UNDERGOING BRAIN COOLING VERSUS STANDARD TREATMENT 01-Feb-02 MULTICENTER INVESTIGATION OF INDUCTION OF STABLE MIXED CHIMERSIM AFTER BONE MARROW TRANSPLANTATION FROM HLA- IDENTICAL DONORS FOR SICKLE CELL DISEASE 07-Feb-02 COMPLICATIONS OF TITANIUM FLEXIBLE INTRAMEDULLARY NAILS IN TREATING PEDIATRIC FEMUR FRACTURES: DIFFERENT COMPLICATIONS FOR OLDER AND YOUNGER PATIENTS 12-Feb-02 BURN INJURIES ON PLAYGROUND EQUIPMENT 18-Feb-02 SPECTRUM OF TORSO INJURIES FROM RIDE-ON LAWNMOWERS: REPORT OF A CASE AND A REVIEW OF THE NATIONAL PEDIATRIC TRAUMA REGISTRY 18-Feb-02 DOUBLE TERMINATION OF THE ALIMENTARY TRACT IN A FEMALE: CASE REPORT AND REVIEW OF THE LITERATURE 18-Feb-02 SPECTRUM OF ANORECTAL MALFORMATIONS IN PYGOPAGUS CONJOINED TWINS 19-Feb-02 MEDICAL COSTS AND CHARACTERISTICS OF INPATIENTS WITH ACCIDENTAL AND ABUSIVE HEAD TRAUMAS 21-Feb-02 A PHASE III, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL TRIAL TO DETERMINE THE EFFICACY AND SAFETY OF ISEGANAN HCL ORAL SOLUTION IN REDUCING THE INCIDENCE AND SEVERITY OF ORAL MUCOSITIS IN PATIENTS RECEIVING STOMATOTOXIC CHEMOTHERAPY 21-Feb-02 CUTANEOUS AND OCULAR MANIFESTATIONS OF FAMILIAL JUVENILE POLYPOSIS AND OTHER GASTROINTESTINAL TRACT POLYPOSIS SYNDROMES 27-Feb-02 MINIMALLY INVASIVE OPEN APPENDECTOMY: AN EFFICACIOUS ALTERNATIVE TO LAPAROSCOPY 27-Feb-02 MORBIDITY AFTER PERCUTANEOUS INSERTION OF CENTRAL LINES IN CHILDREN 27-Feb-02 MINIMALLY INVASIVE TECHNIQUE FOR REMOVAL OF ESOPHAGEAL COINS 12-Mar-02 A SAFETY TRIAL USING RECOMBINANT UROKINASE (ABT-120, UROKINASE ALPHA) IN THE TREATMENT OF OCCLUDED CENTRAL VENOUS CATHETERS 12-Mar-02 PROMOTION OF SEAT BELT AND CHILD RESTRAINT DEVICE USE AMONG SUV OCCUPANTS 12-Mar-02 LONG-TERM SURVIVAL FROM THORACIC SPINE OSTEOSARCOMA AFTER INTRALESIONAL RESECTION AND MULTI-MODAL THERAPY IN AN ELEVEN YEAR OLD FEMALE 12-Mar-02 SCREENING CRITERIA FOR THE RECOGNITION OF CHILD PHYSICAL ABUSE 13-Mar-02 BRAIN COOLING FOR THE TREATMENT OF PERINATAL HYPOXIC-

29 Dr. Elizabeth Ann Esterl, RN October 10, 2017

ISCHEMIC ENCEPHALOPATHY 18-Mar-02 AN EVALUATION OF THE SAFETY AND EFFICACY OF THE SEPTAL REPAIR DEVICE IN PATIENTS WITH SECUNDUM ARTIAL SEPTAL DEFECT (ASD) - AMENDED TO INCLUDE SURGICAL COHORT 27-Mar-02 ADVL0022, A PHASE II STUDY OF GEMITABINE (NSC # 613327) IN CHILDREN WITH RELAPSED ACUTE LYMPHOBLASTIC LEUKEMIA OR ACUTE MYELOGENOUS LEUKEMIA 29-Mar-02 P9761 A PHASE II TRIAL OF IRINOTECAN IN CHILDREN WITH REFRACTORY SOLID TUMORS: A COG STUDY 31-Mar-02 TRAUMATIC RENOVASCULAR INJURY IN CHILDREN 31-Mar-02 ASSESSMENT OF FACTORS THAT INFLUENCE CLOSURE OF GASTROSTOMIES. 31-Mar-02 DETERMINATION OF THE EFFECTIVENESS OF TISSEEL (FIBRIN GLUE) AT REDUCING POST-OPERATIVE CHEST TUBE DRAINAGE AFTER INTERIOR SPINAL EXPOSURE. 31-Mar-02 MALIGNANT THYMOMA IN CHILDREN 03-Apr-02 FETAL ABDOMINAL WALL DEFECTS AND MODE OF DELIVERY: A REVIEW OF THE POPULATION DELIVERED AT UNIVERSITY HOSPITAL 05-Apr-02 PHASE II MULTIPLE DOSE TREATMENT OF TYPE 1 DIABETES MELLITUS WITH HOKT3GAMMA-1 (ALA-ALA) 05-Apr-02 USE OF AN OBSESSIVE-COMPULSIVE SYMPTOM SCREENING TOOL IN A PSYCHIATRIC DEPARTMENT OF A CHILDREN'S HOSPITAL. 08-Apr-02 A PROFILE OF PEDIATRIC EMERGENCY DEPARTMENT RECIDIVISM 08-Apr-02 ACTG A5093, VERSION 1.0: AN OPEN-LABEL, NON-RANDOMIZED STUDY OF PHARMACOKINETIC INTERACTIONS BETWEEN DEPO- MEDROXYYPROGESTERONE ACETATE (DMPA, DEPO-PROVERA ) AND SELECTED PROTEASE INHIBITOR (PI) AND NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR (NNRTI) THERAPIES AMONG HIV-INFECTED WOMEN 11-Apr-02 STUDY FIVE: THE SENSORY ASSESSMENT STUDY DEVELOPING A TEACHER SCALE OF SENSORY FUNCTIONING 11-Apr-02 MEDICAL COSTS, LONGITUDINAL MEDICAL HISTORY AND CHARACTERISTICS OF CHILDREN HOSPITALIZED FOR ACCIDENTAL AND ABUSIVE HEAD TRAUMAS 11-Apr-02 CLINICAL EXPERIENCE WITH 3360 C - 3360 L IN THE DIETARY MANAGEMENT OF AMINO ACID INBORN ERRORS OF METABOLISM 15-Apr-02 ANTIMICROBIAL UTILIZATION OF LEVOFLOXICIN IN A TERTIARY CARE PEDIATRIC HOSPITAL 17-Apr-02 A TWELVE-WEEK, MULTICENTER, DOUBLE MASKED, PARALLEL GROUP, PRIMARY THERAPY STUDY OF THE SAFETY AND EFFICACY OF BETAXON 0.5% COMPARED TO AZOPT 1% IN PEDIATRIC PATIENTS WITH GLAUCOMA OR OCULAR HYPERTENSION 26-Apr-02 REGISTRY OF CRANIOFACIAL TREATMENT OUTCOMES 26-Apr-02 P 9963 A PHASE II TRIAL OF REBECCAMYCIN ANALOGUE (NSC #655649) IN CHILDREN WITH SOLID TUMORS

30 Dr. Elizabeth Ann Esterl, RN October 10, 2017

03-May-02 A RANDOMIZED, DOUBLE-BLIND STUDY OF IBUPROFEN L-LYSINE INTRAVENOUS SOLUTION IN PREMATURE INFANTS FOR THE EARLY TREATMENT OF PDA 08-May-02 PILOTING AN ATTENDING NURSE CARING MODEL WITH CHILDREN IN PAIN 13-May-02 HEALTH UPDATE PROJECT: FEASIBILITY STUDY FOR INTERSEXUAL DISORDERS 16-May-02 PVR GENES IN CLEFT LIP WITH OR WITHOUT CLEFT PALATE 21-May-02 DISTINCTION OF DIFFERENT PARTS OF THE QUADRICEPS FEMORIS IN MUSCLE FIRING 22-May-02 RESPIRATORY OUTCOMES FOR INFANTS WITH CONGENITAL MYOTONIC DYSTROPHY 28-May-02 DATA ABSTRACTION FOR DOSE-FINDING FOR LOW MOLECULAR WEIGHT HEPARIN (LMWH) IN CHILDREN WITH VENOUS THROMBOSIS 28-May-02 DATA ABSTRACTION FOR DOSE-FINDING FOR TISSUE PLASMINOGEN ACTIVATOR (TPA) IN CHILDREN WITH VENOUS THROMBOSIS 31-May-02 IMPACT OF ADENOTONSILLECTOMY FOR SLEEP APNEA ON QUALITY OF LIFE 31-May-02 PREVALENCE AND CHARACTERISTICS OF A TREMOR-ATAXIA DISORDER ASSOCIATED WITH THE FRAGILE X PREMUTATION 03-Jun-02 RESPONSIVE VIRTUAL HUMAN TECHNOLOGY (RVHT) 05-Jun-02 IMPLICATIONS OF INFLUENZA IN CHILDREN WITH BACTERIAL TRACHEITIS 05-Jun-02 THE CHAIRSIDE SEPARATOR SYSTEM (CSS) USER INTERFACE STUDY 10-Jun-02 THE PREVALENCE OF URINARY TRACT INFECTION IN FEBRILE CHILDREN WITH GASTROENTERITIS. 10-Jun-02 INSTRUMENTATION FOR FUSION OF IDIOPATHIC SCOLIOSIS: LENKE 1 CURVE PATTERNS ONLY 19-Jun-02 A PHASE III, DOUBLE-BLIND, RANDOMIZED, COMPARATIVE, MULTICENTER STUDY OF THE IMMUNOGENICITY AND SAFETY OF THREE DOSES OF GLAXOSMITHKLINE BIOLOGICALS/ THIOMERSAL- FREE HEPATITIS B VACCINE (10 MCG/0.5 ML) COMPARED TO THE US- LICENSED GLAXOSMITHKLINE BIOLOGICALS' PRESERVATIVE-FREE HEPATITIS B VACCINE (ENGERIX-B, 10 MCG/0.5 ML) WHEN ADMINISTERED INTRAMUSCULARLY ON A 0, 1, 6-MONTH SCHEDULE TO HEALTHY INFANTS IN THEIR FIRST TWO WEEKS OF LIFE 19-Jun-02 OP-1 IMPLANT 21-Jun-02 COLLECTING AND BANKING RESEARCH SPECIMENS FOR THE STUDY OF ADULT MALIGNANCIES 24-Jun-02 A MULTICENTER, OPEN LABEL, NON-COMPARATIVE TRIAL OF THE SAFETY AND EFFICACY OF FLOXIN OTIC SOLUTION IN THE TREATMENT OF ACUTE OTITIS MEDIA DUE TO HIGHLY PENICILLIN- RESISTANT STREPTOCOCCUS PNEUMONIAE IN CHILDREN WITH TYMPANOSTOMY TUBES 24-Jun-02 DEPTH OF DISSECTION DURING TONSILLECTOMY AND THE

31 Dr. Elizabeth Ann Esterl, RN October 10, 2017

CORRELATION WITH POST-OPERATIVE BLEEDING AND PAIN 26-Jun-02 THE USE OF BOTULINUM TOXIN TYPE A IN THE TREATMENT OF CHILDREN WITH CONGENITAL MUSCULAR TORTICOLLIS 01-Jul-02 SPLENIC FLEXURE VOLVULUS IN CHILDREN 01-Jul-02 CONGENITAL PARAESOPHAGEAL HERNIAS IN PEDIATRIC PATIENTS 01-Jul-02 RECURRENT PSEUDOTUMORS 01-Jul-02 NEURODEVELOPMENTAL ASSESSMENT OF EXTREMELY LOW BIRTH WEIGHT (ELBW) INFANTS: SENSITIVITY AND SPECIFICITY OF THE AGES AND STAGES QUESTIONNAIRES (ASQ) 03-Jul-02 PACTG P1028S VERSION 1.0: HEPATITIS C PREVALENCE IN PERINATALLY-INFECTED HIV POSITIVE CHILDREN ENROLLED IN PACTG 219C 03-Jul-02 SUCCESSFUL MANAGEMENT OF GIANT OMPHALOCELE IN A PREMATURE LOW BIRTH WEIGHT NEONATE UTILIZING A BEDSIDE CLAMPING TECHNIQUE 19-Jul-02 PERCUTANEOUS INTERNAL PULMONARY ARTERY BANDS IN INFANTS WITH HYPOPLASTIC LEFT HEART SYNDROME (HLHS) 22-Jul-02 PROMOTING LANGUAGE DEVELOPMENT DURING WELL CHILD VISITS 23-Jul-02 PARTICIPATION IN GENZYME CORP. FABRY REGISTRY 29-Jul-02 AN OPEN-LABEL STUDY OF LEVOFLAXIN TO EVALUATE BACTERIOLOGIC OUTCOME IN THE TREATMENT OF CHILDREN WHO ARE AT RISK FOR ACUTE OTITIS MEDIA THAT IS DIFFICULT TO TREAT 01-Aug-02 MARCH OF DIMES (MOD) NEWBORN INTENSIVE CARE UNIT (NICU) PILOT PROJECT 05-Aug-02 EFFICACY OF LEFT THORACOSCOPY AND BLUNT MEDIASTINAL DISSECTION DURING NUSS PROCEDURE FOR PECTUS EXCAVATUM 06-Aug-02 PROSPECTIVE OBSERVATIONAL STUDY OF MYLOTARG (GEMTUZUMAB OZOGAMICIN) IN USUAL CARE: PROTOCOL NO. 0903X-100847 09-Aug-02 DEVELOPMENT OF A HOSPITAL-BASED HOME PROGRAM FOR THE USE OF INHALED NITRIC OXIDE IN THE CHRONIC MANAGEMENT OF SEVERE CARDIOPULMONARY DISEASES 09-Aug-02 PROSPECTIVE STUDY OF DEXAMETHASONE IN NEONATAL LUPUS CHB WITH AIM1, AIM2, AIM2A 13-Aug-02 DEVELOPMENT AND CLINICAL VALIDATION OF NEW MEASURES OF DYNAMIC BALANCE BASED ON CENTER OF MASS (COM) AND CENTER OF PRESSURE (COP) DETERMINATION. 16-Aug-02 WALKING PERFORMANCE FOLLOWING GAIT ANALYSIS: THE EFFECT OF NONCOMPLIANCE WITH THERAPEUTIC RECOMMENDATION 16-Aug-02 A MULTICENTER, OPEN-LABEL, STEADY STATE STUDY TO EVALUATE THE PHARMACOKINETICS OF BENAZEPRIL IN PEDIATRIC SUBJECTS 16-Aug-02 DISTAL ESOPHAGEAL PERFORATION AFTER BLUNT TRAUMA IN

32 Dr. Elizabeth Ann Esterl, RN October 10, 2017

CHILDREN 16-Aug-02 A MULTICENTER, RATER-BLIND, RANDOMIZED, AGE-STRATIFIED, PARALLEL-GROUP STUDY COMPARING TWO DOSES OF OXCARBAZEPINE AS MONOTHERAPY IN PEDIATRIC PATIENTS WITH INADEQUATELY-CONTROLLED PARTIAL SEIZURES 18-Aug-02 A MULTICENTER TRIAL OF TOPICAL AMINOGLYCOSIDES TO ACTIVATE CYSTIC FIBROSIS GENES IN CYSTIC FIBROSIS PATIENTS 18-Aug-02 THE EVALUATION OF PLATELET CALMODULIN AS A MARKER IN IDIOPATHIC SCOLIOSIS 21-Aug-02 CLINICAL PERFORMANCE MEASURE FOR PEDIATRIC BRAIN INJURY - PHASE II 23-Aug-02 EFFICACY AND SAFETY OF LEFLUNOMIDE VERSOS METHOTREXATE IN THE TREATMENT OF PEDIATRIC PATIENTS WITH JUVENILE RHEUMATOID ARTHRITIS 28-Aug-02 ASSESSMENT OF CHILDREN WITH SLEEP DISORDERS REQUIRING LABORATORY EVALUATION 28-Aug-02 EFFECT OF BILATERAL PULMONARY ARTERY BANDING JON SURGICAL OUTCOME OF HEART TRANSPLANTATION FOR OLDER INFANTS WITH HYPOPLASTIC LEFT HEART SYNDROME 30-Aug-02 A PHARMACOKINETICS-GUIDED PHASE II TRIAL OF THE REBECCAMYCIN ANALOG NSC# 655649 IN PEDIATRIC PATIENTS WITH RELAPSE/REFRACTORY NEUROBLASTOMA (T98-0041) 03-Sep-02 A PHASE I TRIAL COMPARING SAFETY, SERUM PHARMACOKINETICS AND DELIVERY TIME OF A CONCENTRATED TOBRAMYCIN SOLUTION FOR INHALATION (120 MG/ML) DELIVERED BY AN INVACARE MOBILAIRE(TM) COMPRESSOR TO TOBI (60 MG/ML). DELIVERED BY A DEVILBISS PULMOAIDE (TM) COMPRESSOR IN YOUNG (> 6 MONTHS TO < 12 YEARS OLD) CYSTIC FIBROSIS (CF) PATIENTS 03-Sep-02 PROSPECTIVE EVALUATION OF THE SURGICAL TREATMENT OF PEDIATRIC IDIOPATHIC SCOLIOSIS 05-Sep-02 AMPLATZER PFO OCCLUDER 05-Sep-02 CLINICAL EXPERIENCE IN THE TREATMENT OF OSTEOPOROSIS AT THE CHILDREN'S HOSPITAL - A CHART REVIEW 09-Sep-02 INVESTIGATION OF THE EFFICACY AND SAFETY OF DROTRECOGIN ALFA (ACTIVATED) IN PEDIATRIC SEVERE SEPSIS 09-Sep-02 TEMPORAL TRENDS IN SEVERE RESPIRATORY SYNCYTIAL VIRUS DISEASE IN COLORADO 13-Sep-02 A RANDOMIZED (2:1), STRATIFIED, DOUBLE-BLIND, PARALLEL- GROUP, PLACEBO-CONTROLLED, 12 -WEEK, MULTI-CENTER TRIAL OF FLUTICASONE PROPIONATE HFA INHALATION AEROSOL 88 MCG BID VERSUS PLACEBO HFA DELIVERED VIA AN MDI AND A VALVED HOLDING CHAMBER WITH FACEMASK IN PEDIATRIC SUBJECTS 1 TO 4 YEARS OF AGE WITH ASTHMA; PROTOCOL NUMBER: FAS30030. 18-Sep-02 PARENTS PERSPECTIVE ON SURVIVORSHIP 18-Sep-02 AN OPEN-LABEL, SAFETY AND EFFICACY STUDY OF CEFDINIR ORAL SUSPENSION, 25 MG/KG ONCE DAILY, IN PEDIATRIC SUBJECTS WITH

33 Dr. Elizabeth Ann Esterl, RN October 10, 2017

ACUTE OTITIS MEDIA 20-Sep-02 THE INFLUENCE OF ATTACHMENT RELATIONSHIPS ON COPING PROCESSES AND SUBJECTIVE DISTRESS OF ADOLESCENTS TREATED FOR CANCER 20-Sep-02 GEOGRAPHIC TRENDS IN PNEUMOCOCCAL HOSPITALIZATION IN COLORADO 20-Sep-02 A PHASE I, OPEN-LABEL SAFETY AND TOLERABILITY STUDY OF ORAL THERACLEC-TOTAL IN SUBJECTS WITH CYSTIC FIBROSIS 25-Sep-02 EPIDEMIOLOGY OF PEDIATRIC FEMORAL FRACTURES COMBINED WITH ADDITIONAL INJURIES, INCIDENCE. MECHANISMS AND SOCIODEMOGRAPHIC RISK FACTORS 04-Oct-02 NATURAL HISTORY OF CHRONIC RHINOSINUSITIS IN CHILDREN 04-Oct-02 RESEARCH SUBJECT ADVOCATE PROGRAM ASSESSMENT AND PROGRESS 04-Oct-02 MUSCLE ACTIVITY AND MOVEMENT OF PEOPLE WITH PARKINSON'S DISEASE AND DEEP BRAIN STIMULATORS DURING TREADMILL WALKING WITH SUPPORT 08-Oct-02 TOXIC SHOCK SYNDROME AND RHINOSINUSITIS IN CHILDREN 14-Oct-02 TREATING MENORRHAGIA IN WOMEN WITH BLEEDING DISORDERS 14-Oct-02 PILOT DOSE FINDING AND EFFICACY STUDY OF ANGIOMAX (BIVALIRUDIN) AS PRIMARY ANTICOAGULATION IN NEONATES WITH THROMBOSIS 14-Oct-02 INFLUENZA VACCINATION IN PEDIATRIC RHEUMATOLOGY PATIENTS 15-Oct-02 STUDY OF SAFETY AND EFFICACY OF ANTIHEMOPHILIC FACTOR / VON WILLEBRAND FACTOR COMPLEX (HUMATE-P) USING INDIVIDUALIZED DOSING IN PEDIATRIC AND ADULT SURGICAL PATIENTS WITH VON WILLEBRAND'S DISEASE. 15-Oct-02 SPINAL MUSCULAR ATROPHY TYPE 1: A RETROSPECTIVE REVIEW OF PULMONARY AND NUTRITIONAL INTERVENTIONS 21-Oct-02 NON-ALCOHOLIC STEATOHEPATITIS IN TYPE 2 DIABETIC CHILDREN 04-Nov-02 COMPLICATIONS OF SPINAL ANESTHESIA IN PATIENTS WITH HLHS 11-Nov-02 MEASURABLE CHANGES IN CHILDREN WITH MOVEMENT DELAY FOLLOWING A PEDIATRIC TREATMENT TRAINING COURSE 11-Nov-02 ANALYSIS OF BREATH CONDENSATE IN CHILDREN WITH CYSTIC FIBROSIS 12-Nov-02 A PILOT STUDY OF DIRECTED DONATION, BANKING AND INFUSION OF UMBILICAL CORD BLOOD IN INFANTS AT HIGH RISK FOR DEVELOPING TYPE 1 DIABETES MELLITUS 13-Nov-02 ASCT0031, A PHASE III TRIAL OF HYDROXYCHLOROQUINE + STANDARD THERAPY FOR CHRONIC GRAFT-VERSUS-HOST DISEASE 26-Nov-02 ALLOGENEIC NONMYELOABLATIVE HEMATOPOIETIC STEM CELL TRANSPLANT FOR PATIENTS WITH STI-571PH+ ACUTE LEUKEMIA - A MULTI CENTER TRIAL (FHCRC 1581.00)

34 Dr. Elizabeth Ann Esterl, RN October 10, 2017

27-Nov-02 A PILOT STUDY TO DETERMINE THE INFLUENCE OF THE APOLIPOPROTEIN E GENE ON OUTCOMES IN PEDIATRIC NEUROTRAUMA 06-Dec-02 A PHASE II STUDY OF INTRAVENOUS DX-8951F (EXATECAN MESYLATE) ADMINISTERED DAILY FOR FIVE DAYS EVERY THREE WEEKS TO PEDIATRIC PATIENTS WITH RELAPSED OR REFRACTORY RHABDOMYOSARCOMA 11-Dec-02 DOES ONDANSETRON REDUCE THE INCIDENCE OF VOMITING WHEN USED IN CONJUNCTION WITH KETAMINE DURING PROCEDURAL SEDATION IN THE PEDIATRIC EMERGENCY DEPARTMENT 14-Dec-02 GUIDELINES FOR APPROPRIATE SEDATION AND ANALGESIA PRIOR TO NEUROMUSCULAR BLOCKADE IN THE PEDIATRIC INTENSIVE CARE UNIT 18-Dec-02 THE UTILITY OF THE LANSKY PLAY PERFORMANCE SCALE IN A PEDIATRIC CHRONIC PAIN OUTPATIENT SETTING. 18-Dec-02 ISOLETTE AIR CONTROL VERSUS SKIN CONTROL FOR TEMPERATURE REGULATION OF THE NEONATE 19-Dec-02 ATAZANIVIR (BMS-232632) FOR HIV INFECTED INDIVIDUALS: AN EARLY ACCESS PROGRAM 22-Dec-02 POTENTIAL ASYTOLIC ORGAN DONORS IN A PEDIATRIC INTENSIVE CARE UNIT 02-Jan-03 A MULTICENTER, LONG-TERM, ACTIVE-SURVEILLANCE STUDY OF MUSCULOSKELETAL DISORDERS THAT OCCUR AFTER INITIATING A COURSE OF LEVOFLOXACIN (RWJ-25213-097) OR NON- FLUOROQUINOLONE THERAPY FOR ACUTE INFECTIOUS DISEASES IN CHILDREN WHO WERE ENROLLED IN PHASE 3 CLINICAL TRIALS INVOLVING LEVOFLOXACIN THERAPY PROTOCOL (LOFBO-LTSS-01 (PRI/LOF-INT-4); PHASE 4 07-Jan-03 ESTABLISHMENT AND EVALUATION OF A CASE MANAGEMENT PROGRAM TO ASSIST CLIENTS IN OBTAINING A PCP OR HEALTH INSURANCE 08-Jan-03 IMPLEMENTATION OF ONDANSETRON DOSING GUIDELINES IN POSTOPERATIVE PEDIATRIC PATIENTS 08-Jan-03 PROSPECTIVE POSTUROGRAPHIC ANALYSIS OF ACL RECONSTRUCTION IN ADOLESCENT PATIENTS 08-Jan-03 CASE REPORT OF USE OF CLONIDINE IN AN INFANT 09-Jan-03 EVALUATING THE APPROPRIATENESS OF ADMISSION TO A PEDIATRIC EMERGENCY DEPARTMENT OBSERVATION UNIT. 10-Jan-03 A PILOT, MULTICENTER, OPEN LABEL, NON COMPARATIVE STUDY OF THE SAFETY AND EFFICACY OF FLOXIN OTIC SOLUTION IN THE TREATMENT OF OTITIS MEDIA TWICE DAILY FOR SEVEN DAYS IN CHILDREN WITH TYPANOSTOMY TUBES 13-Jan-03 THE MEDICAL CAREER COLLABORATIVE (MC2) - A FORMULA THAT'S WORKING: THE EFFECTIVENESS OF THE FIRST FOUR YEARS OF MC2 ON ITS PARTICIPANTS AS THEY PREPARE TO GRADUATE 13-Jan-03 EFFECTS OF GROWTH PLATE COMPONENTS ON OSTEOSARCOMA CELLS

35 Dr. Elizabeth Ann Esterl, RN October 10, 2017

16-Jan-03 CCG-E22 A CASE-CONTROL STUDY OF MALIGNANT GERM CELL TUMORS IN CHILDREN 17-Jan-03 THERAPEUTIC DRUG MONITORING OF PROTEASE INHIBITORS IN PREGNANT WOMEN 21-Jan-03 AN OPEN-LABEL, MULTICENTER, SINGLE DOSE STUDY TO EVALUATE THE PHARMACOKINETICS OF GLIMEPIRIDE (AMARYL: IN PEDIATRIC PATIENTS WITH TYPE 2 DIABETES MELLITUS 22-Jan-03 OPEN, RANDOMIZED, PHASE II, CLINICAL TRIAL TO COMPARE THE IMMUNOGENICITY AND SAFETY OF A BOOSTER DOSE OF GSK BIOLOGICALS' DTAP-IPV VACCINE (INFANRIX-IPV) CO- ADMINISTERED WITH A BOOSTER DOSE OF MERCK AND COMPANY'S M-M-RII, TO THAT OF SEPARATE INJECTIONS OF GSK BIOLOGICALS' DTAP VACCINE (INFANRIX), AVENTIS PASTEUR'S IPV (IPOL) AND M- M-RII ADMINISTERED AS BOOSTER DOSES TO HEALTHY CHILDREN 4 TO 6 YEARS OF AGE 22-Jan-03 THE EFFECTIVENESS AND TOLERABILITY OF ATYPICAL ANTIPSYCHOTICS FOR CHILDREN AND ADOLESCENTS 23-Jan-03 ONSET OF HARLEQUIN SYNDROME AFTER NUSS BAR PLACEMENT 24-Jan-03 TRIALNET PREVENTION SCREENING AND STAGING 24-Jan-03 STUDY 08-103: A MULTI-CENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, 28-DAY STUDY OF INS37217 INHALATION SOLUTION IN SUBJECTS WITH MILD TO MODERATE CYSTIC FIBROSIS LUNG DISEASE 24-Jan-03 RETROSPECTIVE REVIEW OF PATIENT CHART AND X-RAYS TO DETERMINE A SINGLE POSSIBLE PARAMETER OF LENGTH OF STAY, I.E. DAY OF WEEK OF ADMISSION, IN SPINAL FUSION SURGERY FOR SCOLIOSIS 24-Jan-03 RETROSPECTIVE REVIEW OF PATIENT CHART AND X-RAYS TO DETERMINE INDICATIONS OR NEED FOR POST-OPERATIVE X-RAYS IN SPINAL FUSION SURGERY FOR SCOLIOSIS 24-Jan-03 A MULTI-CENTER PILOT STUDY OF HIGH-DOSE IMMUNOSUPPRESSIVE THERAPY USING CYCLOPHOSPHAMIDE AND ANTI-THYMOCYTE GLOBULIN AND FOLLOWED BY AUTOLOGOUS OR SYNGENEIC PERIPHERAL BLOOD STEM CELL TRANSPLANTATION FOR PATIENTS WITH REFRACTORY SYSTEMIC LUPUS ERYTHEMATOSUS (COMIRB 01-681/FHCRC1630.00) 27-Jan-03 RETROSPECTIVE ANALYSIS OF CHILDREN WITH TESTICULAR CANCER TREATED AT A SINGLE INSTITUTION 30-Jan-03 A PHASE I/II TRIAL OF PEG12000 INTERFERON ALFA-2B (PEG-INTRON) FOR PLEXIFORM NEUROFIBROMAS 05-Feb-03 DONATION AFTER CARDIAC DEATH (DCD): SURVEY OF THE CHILDREN'S HOSPITAL PROFESSIONAL STAFF 20-Feb-03 THE POSITIVE PREDICTIVE VALUE OF RIB FRACTURES AS IN INDICATOR OF NON-ACCIDENTAL TRAUMA 20-Feb-03 BLUNT DIAPHRAGMATIC RUPTURE IN CHILDREN 20-Feb-03 A RANDOMIZED, MULTICENTER, PARALLEL-GROUP, DOUBLE-BLIND, VEHICLE-CONTROLLED STUDY TO COMPARE PIMECROLIMUS CREAM

36 Dr. Elizabeth Ann Esterl, RN October 10, 2017

1% AND VEHICLE IN PRURITUS IMPROVEMENT AND RELIEF DURING THE FIRST 7 DAYS OF TREATMENT IN PATIENTS _>2 YEARS OLD WITH MILD TO MODERATE ATOPIC DERMATITIS 26-Feb-03 PEDIATRIC INTENSIVE CARE UNIT SEDATION: SURVEY OF FELLOWSHIP TRAINING PROGRAMS 26-Feb-03 METHODS AND COMPLICATIONS OF SPLIT-APPENDIX TECHNIQUES FOR ANTEGRADE CONTINENCE ENEMA 27-Feb-03 STUDY OF LONG-TERM SURVIVORS OF CHILDHOOD CANCER: DISTURBANCES OF THE DEVELOPING DENTITION AND ASSOCIATED ORAL STRUCTURES. 27-Feb-03 ANESTHETIC MANAGEMENT OF CHILDREN WITH NAVAJO NEUROHEPATOPATHY 03-Mar-03 REVIEW OF BOWEL VAGINOPLASTY FOR VAGINAL RECONSTRUCTION 05-Mar-03 DOES A SIMULATED POSITIVE TEST DOSE DETECT THE INTRAVASCULAR INJECTION OF BUPIVACAINE WITH EPINEPHRINE DURING TOTAL INTRAVENOUS ANESTHESIA (TIVA) WITH PROPOFOL AND REMIFENTANIL? 06-Mar-03 GAIT CLASSIFICATION IN CEREBRAL PALSY USING STATISTICAL PATTERN RECOGNITION: RETROSPECTIVE MODEL DEVELOPMENT FROM FEBRUARY 2003 14-Mar-03 A PHASE II STUDY OF INTRAVENOUS DX-8951F (EXATECAN MESYLATE) ADMINISTERED DAILY FOR FIVE DAYS EVERY THREE WEEKS TO PEDIATRIC AND YOUNG ADULT PATIENTS WITH EWING'S SARCOMA (ES), PRIMITIVE NEUROECTOFERMAL TUMOR (PNET), OR DESMOPLASTIC SMALL ROUND CELL TUMOR (DSRT) 14-Mar-03 EATING DISORDERS AND READINESS FOR CHANGE 18-Mar-03 SATISFACTION WITH SICKLE CELL CARE 26-Mar-03 BLOOD BETA-HYDROXYBUTYRATE (BETA-HBA) LEVELS DURING THE TREATMENT OF DIABETIC KETOACIDOSIS (DKA) 26-Mar-03 CHROMOSOMAL MARKERS AND THEIR GENOTYPE/PHENOTYPE CORRELATION 28-Mar-03 PHASE II RANDOMIZED TRIAL OF IRINOTECAN AND CARBOPLATIN VS. IRINOTECAN IN CHILDREN 1-21 YEARS OF AGES WITH REFRACTORY SOLID TUMORS 29-Mar-03 DESCRIPTIVE STUDY OF FAMILIES IN THE SUPPORTIVE CARE NETWORK 01-Apr-03 ASSESSMENT OF A TEEN SICKLE CELL DISEASE FOCUS GROUP 03-Apr-03 COMPASSION FATIGUE/VICARIOUS TRAUMA: A SURVEY OF CHILDREN'S HOSPITAL SOCIAL WORKERS. 03-Apr-03 A GAP ANALYSIS AND EDUCATION INITIATIVE RELATED TO STAFF AWARENESS OF COMIRB GUIDELINES 09-Apr-03 PROMOTION OF CHILD RESTRAINT DEVICE USE IN A LOCAL HISPANIC POPULATION 10-Apr-03 IMPROVING PERFORMANCE OF CF CENTERS IN THE DETECTION AND

37 Dr. Elizabeth Ann Esterl, RN October 10, 2017

MANAGEMENT OF CYSTIC FIBROSIS-RELATED DIABETES MELLITUS 15-Apr-03 PROTOCOL FOR COLLECTING AND STORING CLINICAL INFORMATION FOR THE STUDY OF PEDIATRIC CANCER PATIENTS 16-Apr-03 FLEXION TYPE SUPRACONDYLAR HUMERUS FRACTURES IN CHILDREN 23-Apr-03 THE USE OF A COMPREHENSIVE TOOL TO COMPARE PHARMACEUTICAL PRACTICES BETWEEN HOSPITALS 23-Apr-03 CHOREOATHETOSIS AFTER OPEN HEART SURGERY - AN IATROGENIC EPIDEMIC? 23-Apr-03 A COMPARISON OF EXERCISE RESPONSES IN CHILDREN AT SEA LEVEL AND ALTITUDE: A RETROSPECTIVE REVIEW 24-Apr-03 A MULTI-CENTER, IN-PATIENT, OPEN-LABEL, DOSE RANGING STUDY TO CHARACTERIZE THE PHARMACOKINETICS AND SAFETY OF AN ORAL LIQUID FORMULATION OF OXYCODONE IN PATIENTS FROM BIRTH TO 4 YEARS OF AGE, WHO REQUIRE OPIOID ANALGESIA 30-Apr-03 PREVALENCE OF EATING DISORDER SYMPTOMS IN OVERWEIGHT YOUTH 30-Apr-03 A MULTICENTER, OPEN-LABEL, MULTIPLE-DOSE STUDY OF THE CONVERSION FROM IMMEDIATE RELEASE OXYCODONE (OXYIR) TO CONTROLLED RELEASE OXYCODE (OXYCONTIN) TO EVALUATE PHARMACOKINETICS AND TO CHARACTERIZE SAFETY AND EFFICACY IN PEDIATRIC PATIENTS 6 TO 16 YEARS OF AGE (PROTOCOL # OXP3004 TREATMENT AND EXTENSION PHASE) 30-Apr-03 A RETROSPECTIVE, CHART REVIEW, DETERMINING EFFICACY AND ADVERSE EFFECTS OF PRIMSOL TRIMETHOPRIM SOLUTION FOR PROPHYLAXIS OF THE UPPER URINARY TRACT IN PEDIATRIC PATIENTS WITH VESICOURETERAL REFLUX 02-May-03 MULTICENTER, DOUBLE BLIND, RANDOMIZED, DOSE RANGING STUDY, IN PEDIATRIC PATIENTS 5 TO <16 YEARS OF AGE RECEIVING MORPHINE AS STANDARD SUPPLEMENTAL PAIN MEDICATION, TO EVALUATE PHARMACOKINETICS, SAFETY AND EFFICACY OF OXY PEDIATRIC LIQUID (1MG/ML) VERSUS PLACEBO IN THE TREATMENT OF ACUTE MODERATE TO SEVERE PAIN. 03-May-03 PROTOCOL FOR COLLECTING AND STORING CLINICAL INFORMATION FOR THE STUDY OF PEDIATRIC HEMATOPOIETIC STEM CELL TRANSPLANT 08-May-03 STAFF PERCEPTIONS OF THE ROLE OF INFORMATION TECHNOLOGY AS A RESULT OF THE HEALTH INSURANCE PORTABILITY AND PRIVACY ACT 09-May-03 TREATMENT OF PREPUBERTAL LABIAL ADHESIONS WITH BETAMETHASONE CREAM 09-May-03 CARDIOPULMONARY EXCERCISE TESTING (CPT)IN PEDIATRIC HEART TRANSPLANT CANDIDATES 14-May-03 PROTOCOL FOR COLLECTING AND STORING CLINICAL INFORMATION FOR THE STUDY OF PEDIATRIC NEUROONCOLOGY 16-May-03 A STRATIFIED, RANDOMIZED, DOUBLE-BIND, PLACEBO- CONTROLLED, PARALLEL GROUP, 12-WEEK TRIAL EVALUATING THE

38 Dr. Elizabeth Ann Esterl, RN October 10, 2017

SAFETY AND EFFICACY OF THE FLUTICASONE PROPIONATE/SALMETEROL DISKUS COMBINATION PRODUCT 100/50 MCG ONCE DAILY VERSUS FLUTICASONE PROPIONATE DISKUS 100MCG ONCE DAILY AND PLACEBO IN SYMPTOMATIC PEDIATRIC SUBJECTS (4-11 YEARS) WITH ASTHMA 19-May-03 ARE ADOLESCENTS DIAGNOSED WITH ANOREXIA NERVOSA, BINGE- EATING/PURGING TYPE MORE SIMILAR TO ADOLESCENTS DIAGNOSED WITH ANOREXIA NERVOSA, RESTRICTING TYPE OR BULIMIA NERVOSA IN TERMS OF CO-MORBID PSYCHIATRIC SYMPTOMS? 22-May-03 ASSOCIATION OF CYTOCHROME P450 GENOTYPES AND TREATMENT RESPONSE IN PEDIATRIC ACUTE LEUKEMIA 27-May-03 RETROSPECTIVE REVIEW OF PATIENTS CHARTS TO DETERMINE THE EFFECTIVENESS OF THE HIGH RISK PATHWAY FOR PATIENTS WHO UNDERWENT SPINE FUSION SURGERY FOR NEUROMUSCULAR SCOLIOSIS 03-Jun-03 A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO- CONTROLLED, PARALLEL-GROUP STUDY IN PEDIATRIC PATIENTS OF THE SAFETY AND THE PHARMACOKINETIC PROFILE OF TWO DIFFERENT INTRAVENOUS DOSES OF TMA-15 10-Jun-03 EVALUATION OF STATLOCK AS AN AID FOR SECURING INDWELLING EPIDURAL CATHETERS 13-Jun-03 INFORMED CONSENT FOR GENETIC SCREENING 16-Jun-03 NON COMPLETED REFERRALS FROM SPECIAL CARE CLINIC: AN ASSESSMENT OF FREQUENCY AND REASONS 16-Jun-03 PILOT STUDY OF OUTCOMES OF CHILDREN WITH KAISER INSURANCE TRIAGED BY THE AFTER-HOURS CALL CENTER 16-Jun-03 POINT OF CARE INSTRUMENT FOR VIRAL RESPIRATORY DIAGNOSIS 17-Jun-03 SMITH-LEMLI-OPITZ (SLO) SYNDROME QUESTIONNAIRE 17-Jun-03 CAROTID ULTRASOUND TRAINING FOR CERTIFICATION 24-Jun-03 SURVEY OF MEDICAID PARTICIPATION AMONG PEDIATRICIANS AND FAMILY PHYSICIANS IN COLORADO. 24-Jun-03 RETROSPECTIVE EVALUATION OF OUTCOMES OF IMMUNOSUPPRESSIVE THERAPY FOR SEVERE APLASTIC ANEMIA IN CHILDREN AT THE UCHSC DEPARTMENT OF PEDIATRICS/DIVISION OF HEMATOLOGY, 1900-2002 27-Jun-03 A PHASE II, OPEN-LABEL STUDY OF CLOFAREX IN PEDIATRIC PATIENTS WITH REFRACTORY OR RELAPSED ACUTE MYELOGENOUS LEUKEMIA 01-Jul-03 CLINICAL EFFICACY AND SAFETY OF MESALAMINE SUPPOSITORIES (CANASA SALOFALK) IN THE TREATMENT OF PEDIATRIC ULCERATIVE PROCTITIS: A MULTI-CENTER, OPEN LABEL, PARALLEL GROUP STUDY 03-Jul-03 CONTROLLED TRIAL OF INDUCTION THERAPY IN RENAL TRANSPLANTATION / COOPERATIVE CLINICAL TRIALS IN PEDIATRIC TRANSPLANTATION

39 Dr. Elizabeth Ann Esterl, RN October 10, 2017

03-Jul-03 PROCLEIX WEST NILE VIRUS ASSAY FOR SCREENING OF VOLUNTARY DONATIONS OF WHOLE BLOOD OR SOURCE PLASMA 10-Jul-03 AN EVALUATION OF PROVIDER - PATIENT COMMUNICATION: QUALITY ASSURANCE AND NEEDS ASSESSMENT 15-Jul-03 BREATHE BETTER ASTHMA SCREENING: DETECTION OF ASTHMA SYMPTOMS IN AN UNDERSERVED POPULATION 18-Jul-03 AN OPEN-LABEL MULTICENTER, STUDY OF THE SAFETY AND ANTIEMETIC EFFECT OF 0.15 MG/KG INTRAVENOUS ONDANSETRON HYDROCHLORIDE ADMINISTERED FOR THREE DOSES TO PEDIATRIC CANCER PATIENTS AGE 6 MONTHS TO 48 MONTHS WHO ARE RECEIVING MODERATELY TO HIGHLY EMETOGENIC CHEMOTHERAPY. S3A40320 18-Jul-03 A 7-DAY, OPEN-LABEL, MULTICENTER, PHARMACOKINETIC STUDY (PART 1) FOLLOWED BY A 7-DAY, RANDOMIZED, MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-RANGING, PARALLEL GROUP STUDY (PART 2) OF IV SILDENAFIL IN THE TREATMENT OF NEONATES WITH PERSISTENT PULMONARY HYPERTENSION OF THE NEWBORN (PPHN) OR HYPOXIC RESPIRATORY FAILURE AT RISK FOR PPHN 18-Jul-03 NURSES' PERCEPTIONS OF THE WORK ENVIRONMENT IN A PEDIATRIC TERTIARY CARE SETTING 22-Jul-03 A COMPREHENSIVE ASSESSMENT OF PEDIATRIC AFTER-HOURS TELEPHONE CARE: ONE YEAR'S EXPERIENCE 22-Jul-03 CORRECTION OF FACTITIOUS HYPERKALEMIA IN HEMOLYZED SPECIMENS 01-Aug-03 THE IMPACT OF HOSPITALIZATION UPON SLEEP EFFICIENCY IN CYSTIC FIBROSIS PATIENTS 05-Aug-03 A PHASE 1 SINGLE-DOSE, DOSE-ESCALATION TRIAL COMPARING SAFETY, PHARMACOKINETICS, AND DELIVERY TIME OF TOBRAMYCIN POWDER FOR INHALATION (TPI POWDER) ADMINISTERED BY THE NEKTAR T-326 DRY POWDER INHALER DEVICE (T-326 INHALER) TO TOBRAMYCIN SOLUTION FOR INHALATION (TOBIr AT 300MG/5ML) ADMINISTERED BY A PARI LC PLUS JET NEBULIZER/DEVILBISS PULMOAIDE COMPRESSOR IN CYSTIC FIBROSIS (CF) PATIENTS 07-Aug-03 PROSPECTIVE EVALUATION OF DAILY LOW-DOSE WARFARIN PROPHYLAXIS FOR CENTRAL VENOUS CATHETER-ASSOCIATED THROMBOSIS IN CHILDREN WITH CANCER 12-Aug-03 HEALTH CARE SERVICES FOR CHILDREN PLACED IN FOSTER OR KINSHIP CARE 12-Aug-03 A PILOT STUDY TO DETERMINE THE FREQUENCY AND SIGNIFICANCE OF BCL-6 EXPRESSION AND MUTATION IN POST-TRANSPLANTATION LYMPHOPROLIFERATIVE DISORDER IN CHILDREN 12-Aug-03 COMPARISON OF THE SAFETY AND EFFICACY OF DRUGS USED FOR PEDIATRIC PROCEDURAL SEDATION AND ANALGESIA IN THE EMERGENCY DEPARTMENT. 14-Aug-03 A COMPARISON OF ORAL PREDNISONE VERSUS ORAL DEXAMETHASONE IN THE MANAGEMENT OF PEDIATRIC ASTHMA

40 Dr. Elizabeth Ann Esterl, RN October 10, 2017

EXACERBATIONS 14-Aug-03 KIMS-DATA ENTRY FOR ADULTS ON GROWTH HORMONE 19-Aug-03 NATIONAL AIRWAY CLEARANCE REGISTRY (NACR) 19-Aug-03 "STUDY OF MEDICATIONS FOR TREATMENT OF NEUROLOGICAL SYMPTOMS ASSOCIATED WITH THE FRAGILE X PREMUTATION" 22-Aug-03 A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, DOSE RANGING, PARALLEL GROUP STUDY OF ORAL SILDENAFIL IN THE TREATMENT OF CHILDREN, AGED 1-16 YEARS, WITH PULMONARY ARTERIAL HYPERTENSION (PROTOCOL A1481131 AND AMENDMENT 1-28, AUGUST 2003 AND AMENDMENT 2-17, DECEMBER 2003) 26-Aug-03 RETROSPECTIVE REVIEW OF CHILDREN WITH TRACHEOSTOMY TREATED AT THE CHILDREN'S HOSPITAL 26-Aug-03 DETERMINATION OF NURSES' PERCEPTIONS OF THE NON-TASK DEPENDENCIES OF PATIENTS, THEIR FAMILIES, AND THEIR CAREGIVERS 29-Aug-03 PERCUTANEOUS PULMONARY ARTERY BANDING WITH THE AMPLATZER FLOW RESTRICTOR DEVICE 29-Aug-03 A RANDOMIZED, MULTICENTER, DOUBLE-BLIND, PLACEBO- CONTROLLED, DOSE-RANGING, PARALLEL GROUP STUDY OF INTRAVENOUS SILDENAFIL IN THE TREATMENT OF CHILDREN, AGED 0 TO 17 WITH PULMONARY HYPERTENSION AFTER CORRECTIVE CARDIAC SURGERY 29-Aug-03 A MULTICENTER, RANDOMIZED, DOUBLE-BLIND CLINICAL TRIAL EVALUATING THE SAFETY AND EFFICACY OF GLUCOVANCE VERSUS METFORMIN AND GLYBURIDE MONOTHERAPIES IN PEDIATRIC PATIENTS WITH TYPE 2 DIABETES MELLITUS (CV 138-059) 03-Sep-03 A PHASE IIA, SAFETY AND EFFICACY STUDY OF ORAL SPI-8811 IN PATIENTS WITH CYSTIC FIBROSIS (CF) 03-Sep-03 EXPRESSION OF CYCLOXYGENASE AND LIPOXYGENASE ENZYMES IN NASAL POLYP TISSUE FROM ASPIRIN-SENSITIVE AND ASPIRIN- TOLERANT AND CYSTIC FIBROSIS PATIENTS 04-Sep-03 PARENTS' PERCEPTION OF DEAF AND HARD OF HEARING TODDLER GROUP 04-Sep-03 CEREBRAL ISCHEMIA AND CEREBRAL EDEMA IN CHILDREN WITH DIABETIC KETOACIDOSIS 09-Sep-03 PLATELET FUNCTION ANALYSIS POST TRANSFUSION IN CHILDREN FOLLOWING HEMATOPOIETIC STEM CELL TRANSPLANTATION 11-Sep-03 COMPARISON OF ANTIBIOTIC USAGE BETWEEN HOSPITALS 19-Sep-03 AN OPEN-LABEL, RANDOMIZED, NON-INFERIORITY STUDY OF NOVEL ERYTHROPOIESIS STIMULATING PROTEIN (NESP) AND RECOMBINANT HUMAN ERYTHROPOIETIN (RHUEPO) FOR THE TREATMENT OF ANEMIA IN PEDIATRIC SUBJECTS WITH CHRONIC RENAL INSUFFICIENCY (CRI) OR END-STAGE RENAL DISEASE (ESRD) RECEIVING DIALYSIS 25-Sep-03 A COMPARATIVE EVALUATION OF CLINICAL INTERPRETIVE MODALITIES: TELEPHONIC VERSUS IN-PERSON

41 Dr. Elizabeth Ann Esterl, RN October 10, 2017

02-Oct-03 RETROSPECTIVE STUDY OF COMPUTERIZED TOMOGRAPHY- GUIDED/CONFIRMED PEDIATRIC INTERVENTIONAL PAIN PROCEDURES 02-Oct-03 MUCOPOLYSACCHARIDOSIS, TYPE I (MPS 1) DISEASE REGISTRY: A MULTICENTER, LONGITUDINAL, OBSERVATIONAL STUDY 02-Oct-03 PILOT STUDY OF AN EVIDENCE SUPPORTED, FAMILY BASED WEIGHT LOSS PROGRAM FOR CHILDREN AND ADOLESCENTS WITH TYPE 2 DIABETES 04-Oct-03 RELIABILITY OF VENTRICULAR SIZE IN ASSESSING CSF SHUNT FAILURE 09-Oct-03 A PHASE II/III CLINICAL STUDY FOR THE DETERMINATION OF THE EFFICACY AND SAFETY OF PROTEIN C CONCENTRATE IN SUBJECTS WITH SEVERE CONGENITAL PROTEIN C DEFICIENCY 10-Oct-03 A PHASE III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED SAFETY AND EFFICACY STUDY OF SITAXSENTAN SODIUM TREATMENT WITH AN OPEN-LABEL BOSENTAN ARM IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION 10-Oct-03 OCULAR INJURIES IN CHILDREN AFTER MAJOR TRAUMA 10-Oct-03 AACTG A5084, VERSION 1.0: EVALUATION OF METABOLIC COMPLICATIONS ASSOCIATED WITH ANTIRETROVIRAL MEDICATIONS IN HIV-1-INFECTED PREGNANT WOMEN 14-Oct-03 GENETIC MODIFIERS OF CF: SIBLING STUDY 14-Oct-03 EPIDEMIOLOGY AND NATURAL HISTORY OF CF 14-Oct-03 BEDSIDE STERILITY TESTING OF REPACKAGED FAT EMULSION AT 20 - 24 HOURS AFTER INFUSION INITIATION 14-Oct-03 A DOUBLE BLIND, RANDOMIZED, MULTICENTER STRATIFIED STUDY TO ASSESS THE SAFETY OF AN INTRAVENOUS STAPHYLOCOCCUS AUREUS IMMUNE GLOBULIN (HUMAN) {ALTASTAPH} IN LOW BIRTH WEIGHT NEONATES 17-Oct-03 A PHASE I STUDY OF COMBINATION THERAPY WITH IMMUNOTOXINS IMTOX 19 (IGG-HD370SMPTODGA) PLUS IMTOX 22 (IGG-RFB4-SMPT- DGA) IN CHILDREN WITH REFRACTORY/RELAPSED CD10 (+), CD22 (+) B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA 21-Oct-03 EFFECTS OF MULTIPLE ANTI-SPASTICITY INJECTIONS ON GAIT IN CEREBRAL PALSY 21-Oct-03 LATE PRESENTING SHUNT INFECTIONS 21-Oct-03 THREE-YEAR EXPERIENCE WITH INFLIXIMAB INFUSIONS IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE (IBD). 21-Oct-03 BRAIN-COOLING FOR THE TREATMENT OF PERINATAL HYPOXIC- ISCHEMIC ENCEPHALOPATHY - CONTINUED ACCESS PROTOCOL 23-Oct-03 CORTICOSTEROID TREATMENT IN DUCHENNE MUSCVULAR DYSTROPHY: LONG-TERM EFFECTS IN DISEASE PROGRESS 23-Oct-03 PEDIATRIC ANESTHETIC IMPLICATIONS ASSOCIATED WITH KAWASAKI DISEASE 23-Oct-03 EFFECTIVE CLINICAL PERFORMANCE MONITORING OF

42 Dr. Elizabeth Ann Esterl, RN October 10, 2017

BRONCHIOLITIS PATIENTS 24-Oct-03 EVALUATION OF INFANTILE ACID AND NON-ACID GASTROESOPHAGEAL REFLUX UTILIZING COMBINED PH MONITORING AND IMPEDANCE MEASUREMENT. 24-Oct-03 EVALUATION OF GASTROESOPHAGEAL REFLUX IN PEDIATRIC PATIENTS WITH PULMONARY DISEASE UTILIZING IMPEDANCE MONITORING 28-Oct-03 A MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE II STUDY OF AEROSOLIZED TGAAVCF FOR THE TREATMENT OF CYSTIC FIBROSIS 28-Oct-03 MICAFUNGIN PROTOCOL FG-463-21-08-"A MULTICENTER, DOUBLE- BLIND, COMPARATIVE, RANDOMIZED,STUDY TO EVALUATE THE EFFICACY AND SAFETY OF MICAFUNGIN (FK463) VERSUS LIPOSOMAL AMPHOTERICIN B (AMBISOME) IN THE TREATMENT OF INVASIVE CANDIDIASIS AND CANDIDEMIA" 28-Oct-03 GREATER TROCHANTERIC TRANSFER: BIOMECHANICAL ANALYSIS AND RESULTS. 28-Oct-03 GONADOBLASTOMA AND TURNERS SYNDROME 28-Oct-03 TEEN AND YOUNG ADULT GROUP 30-Oct-03 LOCAL RESISTANCE PATTERNS IN PEDIATRIC URINARY TRACT INFECTIONS - A RETROSPECTIVE REVIEW 30-Oct-03 OUTCOME OF HEART TRANSPLANTATION FOLLOWING FAILED FONTAN OR CAVO-PULMONARY SHUNT PALLIATION 06-Nov-03 PROTOCOL CANCER RESEARCH NETWORK (CCRN) 06-Nov-03 PILOT STUDY OF SUB SARTORIAL SAPHENOUS NERVE BLOCK 06-Nov-03 RETROSPECTIVE CHART REVIEW OF: "INTRAVENOUS VALPROATE (VPA) FOR ACUTE ADOLESCENT MIGRAINE" 06-Nov-03 PEDS-CORI PEDIATRIC ENDOSCOPIC DATABASE SYSTEM - CLINICAL OUTCOMES RESEARCH INITIATIVE 10-Nov-03 OPEN-LABEL STUDY TO EVALUATE THE LONG-TERM SAFETY OF SITAXSENTAN SODIUM TREATMENT WITH A BOSENTAN ARM IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION. 10-Nov-03 A LONG-TERM OPEN-LABEL STUDY TO EVALUATE THE SAFETY OF SITAXSENTAN SODIUM TREATMENT IN PATIENTS WITH PULMONARY HYPERTENSION. 12-Nov-03 IMPACT OF SPECIAL PRIMARY CARE CLINIC ON TCH 14-Nov-03 A BLINDED, MULTICENTER, RANDOMIZED, PLACEBO-CONTROLLED TRIAL WITH AZTREONAM FOR INHALATION (AI) IN CYSTIC FIBROSIS PATIENTS WITH LUNG DISEASE DUE TO P. AERUGINOSA INFECTION (CP-AI-003) 24-Nov-03 ENDOTHELIAL FUNCTION IN PATIENTS WITH MARFAN SYNDROME: A PILOT INVESTIGATION 25-Nov-03 USE OF BOTULINUM TOXIN INJUECTIONS TO DELAY ACHILLES TENDON LENGTHENINGS, A RETROSPECTIVE REVIEW 03-Dec-03 A FOUR-WEEK, RANDOMIZED, DOUBLE-BLIND, PLACEBO-

43 Dr. Elizabeth Ann Esterl, RN October 10, 2017

CONTROLLED, PARALLEL-GROUP, MULTI-CENTER STUDY OF VENTOLIN-F HFA MDI DELIVERED WITH A FACEMASK AND TWO DIFFERENT HOLDING CHAMBERS IN SUBJECTS AGED 24 TO <48 MONTHS WITH ASTHMA SYMPTOMS (I.E., WHEEZE, COUGH, DYSPNEA, OR CHEST TIGHTNESS) OR CONSISTENT WITH ASTHMA OR OBSTRUCTIVE AIRWAY DISEASE OR BRONCHOSPASM. 09-Dec-03 A RANDOMIZED, 2-PERIOD, MULTICENTER, DOUBLE-BLIND, PARALLEL-GROUP STUDY COMPARING THE EFFECTS OF 2 DOSES OF MONTELUKAST GRANULES AND PLACEBO IN THE TREATMENT OF RESPIRATORY SYMPTOMS ASSOCIATED WITH RESPIRATORY SYNCTIAL VIRUS-INDUCED BRONCHIOLITIS IN CHILDREN AGED 3 TO 24 MONTHS( PROTOCOL/AMENDMENT 272-07) 09-Dec-03 FREQUENCY OF ASCA ANTIBODIES IN PEDIATRIC PATIENTS WITH CYSTIC FIBROSIS 10-Dec-03 INFLUENZA VACCINE EFFECTIVENESS STUDY AMONG HEALTH CARE WORKERS 12-Dec-03 STUDY OF THE SAFETY AND EFFECTIVENESS OF THE MENTOR SOFT- SOLID TESTICULAR PROSTHESIS 17-Dec-03 PARTICIPATION BY CHILDREN IN LIFE SITUATIONS FOLLOWING NEUROTRAUMA: A PRELIMINARY INVESTIGATION INTO THE RELATIONSHIP BETWEEN FUNCTIONAL SKILL COMPETENCE AND OCCUPATIONAL PERFORMANCE. 18-Dec-03 ACCEPTABILITY OF USING GENERAL ANESTHESIA FOR DRESSING CHANGES IN EB PATIENTS 30-Dec-03 CEREBROSPINAL FLUID VANCOMYCIN CONCENTRATIONS FOLLOWING INTRAVENOUS THERAPY IN CHILDREN 30-Dec-03 FORMOCRESOL VS. FERRIC SULFATE AS PULPOTOMY MEDICAMENTS: A RETROSPECTIVE CHART REVIEW 07-Jan-04 TREATMENT OF ADOLESCENT HALLUX VALGUS WITH THE DOUBLE FIRST METATARSAL OSTEOTOMY: THE DENVER EXPERIENCE 07-Jan-04 ALTE02C1 QUALITY OF LIFE IN CHILDREN WHO SURVIVED NEUROBLASTOMA 16-Jan-04 ASSESSMENT AND MONITORING OF LIPID ABNORMALITIES IN HIV- INFECTED INDIVIDUALS ON PROTEASE INHIBITORS 16-Jan-04 A RETROSPECTIVE REVIEW OF THE USE OF RISPERIDONE FOR THE TREATMENT OF ANOREXIA NERVOSA 16-Jan-04 A PHASE I/II STUDY OF LOPINAVIR/RITONAVIR IN HIV-1 INFECTED INFANTS < 6 MONTHS OF AGE (PACTG P1030) 20-Jan-04 RETROSPECTIVE STUDY OF NON-CT GUIDED PEDIATRIC INTERVENTIONAL PAIN PROCEDURES 20-Jan-04 ORIENTATION OF THE LARYNX DURING USE OF THE COBRA PERILARYNGEAL AIRWAY (PLA) AND LARYNGEAL MASK AIRWAY (LMA) IN INFANTS AND CHILDREN 23-Jan-04 A RANDOMIZED, INVESTIGATOR-BLIND, MULTICENTER STUDY TO ASSESS THE BACTERIOLOGICAL EFFICACY OF ORAL AMOXICILLIN/CLAVULANATE (AUGMENTIN ES-600) 90/6.4MG/KG/D TWICE DAILY FOR 10 DAYS VERSUS ORAL CEFDINIR (OMNICEF) 14

44 Dr. Elizabeth Ann Esterl, RN October 10, 2017

MG/KG/D TWICE DAILY FOR 10 DAYS IN THE TREATMENT OF ACUTE OTITIS MEDIA IN INFANTS AND CHILDREN 27-Jan-04 AN EVALUATION OF THE DURATION OF PLATELET DYSFUNCTION FOLLOWING NSAID USE 29-Jan-04 KIDSTREET PROGRAM EVALUATION 03-Feb-04 PROTOCOL FOR COLLECTING AND STORING CLINICAL INFORMATION FOR THE STUDY OF THROMBOPHILIA 04-Feb-04 AN OUTBREAK OF ENTEROVIRUS-71 DISEASE IN COLORADO 06-Feb-04 PACTG P1045: PREVALENCE OF MORPHOLOGIC AND METABOLIC ABNORMALITIES IN VERTICALLY HIV-INFECTED AND UNINFECTED CHILDREN AND YOUTH 10-Feb-04 CAN EARLY HOSPITAL DISCHARGE, REGARDLESS OF ANC, BE SAFELY EXECUTED IN NEUTROPENIC CHILDREN UNDERGOING INDUCTION TREATMENTS FOR NEWLY DIAGNOSED ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)? 11-Feb-04 EFFECTS OF PALATAL FEEDING OBUTURATOR ON PATIENTS WITH CLEFT LIP AND/OR PALATE 17-Feb-04 RESULTS AND COMPLICATIONS WITH SECOND LOOK SURGERY IN THE TREATMENT OF PEDIATRIC EPENDYMOMAS 17-Feb-04 A DOUBLE-BLIND SAFETY AND EFFICACY STUDY OF SITAXSENTAN SODIUM TREATMENT IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION WHO HAVE FAILED BOSENTAN THERAPY 17-Feb-04 IMPACT OF HLA MATCHING ON OUTCOME IN PEDIATRIC PATIENTS UNDERGOING UNRELATED UMBILICAL CORD BLOOD TRANSPLANTATION 19-Feb-04 THE ORAL HEALTH KNOWLEDGE, OPINIONS, AND PRACTICES OF NON-ENGLISH SPEAKING HISPANIC PARENTS COMPARED TO ENGLISH SPEAKING HISPANIC PARENTS. 25-Feb-04 VACCINE PREVENTABLE DISEASE IN THE USA 25-Feb-04 THE EFFECT OF INTRATHECAL BACLOFEN ON SCOLIOSIS 03-Mar-04 SUBMUSCULAR BRIDGE PLATING FOR PEDIATRIC FEMUR FRACTURES. 03-Mar-04 PROPHYLACTIC ANTIBIOTICS AND CSF SHUNT INFECTION 08-Mar-04 THE USE OF BOTULINUM TOXIN A (BOTOX) IN TREATING THE SUBSCAPULARIS MUSCLE IN CHILDREN WHO HAVE CONGENITAL BRACHIAL PLEXUS LESIONS AND INTERNAL ROTATION LIMITATIONS 09-Mar-04 EVALUATION OF EFFICACY OF CIDOFOVIR FOR TREATMENT OF ADENOVIRAL INFECTIONS IN BONE MARROW TRANSPLANT PATIENTS 09-Mar-04 CAREGIVER ASSESSMENT OF PUSHRIM-ACTIVATED, POWER-ASSIST WHEELCHAIRS IN PEDIATRICS 09-Mar-04 PULMONARY VASCULAR REACTIVITY IN CHILDREN AND ADOLESCENTS WITH BRONCHOPULMONARY DYSPLASIA 17-Mar-04 PACTG P1042S: COGNITIVE, BEHAVIORAL, AND PSYCHOSOCIAL

45 Dr. Elizabeth Ann Esterl, RN October 10, 2017

CORRELATES OF MEDICATION ADHERENCE IN CHILDREN AND ADOLESCENTS WITH HIV-1 INFECTION 26-Mar-04 SAFETY AND EFFICACY OF THORACIC EPIDURALS IN PEDIATRIC POPULATION 26-Mar-04 GROWTH AND METABOLIC CONSEQUENCES OF BLADDER AUGMENTATION IN CHILDREN WITH MYELOMENINGOCELE AND BLADDER EXSTROPHY 26-Mar-04 AN INTERNATIONAL, MULTICENTER, RANDOMIZED, OPEN-LABEL, PARALLEL EFFICACY AND SAFETY TRIAL OF INTRAVENOUS ZOLEDRONIC ACID COMPARED TO INTRAVENOUS PAMIDRONATE IN CHILDREN WITH SEVERE OSTEOGENESIS IMPERFECTA 31-Mar-04 PATTERN RECOGNITION IN CHILDREN BY PEDIATRIC RESIDENTS 31-Mar-04 A PHASE 2, RANDOMIZED, DOUBLE BLIND, PARALLEL DOSE RANGING STUDY OF ORAL THERACLECTM-TOTAL IN CYSTIC FIBROSIS SUBJECTS WITH EXOCRINE PANCREATIC INSUFFICIENCY (TC-2A) 01-Apr-04 PARENTAL PERCEPTION OF ORAL REHABILITATION UTILIZING GENERAL ANESTHESIA AT 2-3 WEEK POST-OPERATIVE APPOINTMENT; RISK VERSUS BENEFIT, IS IT WORTH IT? 06-Apr-04 HIP SPICA CASTS AND SKIN FITNESS IN CHILDREN: GORE-TEX VERSUS TRADITIONAL COTTON CAST LINERS. 06-Apr-04 TRENDS IN PEDIATRIC SKIER AND SNOWBOARDER INJURIES IN COLORADO 06-Apr-04 CHILDHOOD DEATHS FROM NON-ACCIDENTAL TRAUMA 08-Apr-04 FAMILY SATISFACTION WITH CLINICAL SOCIAL WORK IN A CHILDREN'S HOSPITAL 21-Apr-04 PSYCHIATRIC DAY TREATMENT FOR SCHOOL REFUSAL 27-Apr-04 TREATMENT OF CYSTIC FIBROSIS PATIENTS WITH ANTIOXIDANT SOLUTION: A PILOT STUDY 28-Apr-04 SENSITIVITY AND SPECIFICITY OF A NOVEL MYCOBACTERIUM AVIUM SUBSPECIES PARATUBERCULOSIS PROBE IN PEDIATRIC BOWEL DISEASES 28-Apr-04 FOLLOW-UP IMAGING OF CLOSED HEAD INJURY WITH INTRACRANIAL BLEED – ARE REPEAT HEAD CT’S NECESSARY? 30-Apr-04 PRESSURE ANALYSIS IN PULMONARY HYPERTENSION 03-May-04 PHYSICIAN KNOWLEDGE OF EMTALA AT AN ACADEMIC TERTIARY CARE PEDIATRIC HOSPITAL 05-May-04 MEASUREMENT OF CARDIAC OUTPUT IN CHILDREN UNDERGOING CARDIAC SURGERY 05-May-04 SEROPREVALENCE AND INCIDENCE OF WEST NILE VIRUS ANTIBODIES IN TRANSPLANT RECIPIENTS: CORRELATION WITH CLINICAL OUTCOME AND NEUROLOGIC SEQUELAE 11-May-04 EFFECTIVENESS OF CARIOLOGY AND ART IN A RESIDENCY PROGRAM 13-May-04 SURVEY FOR ASSESSING DENTAL CARE IN THE HOSPITAL SETTING

46 Dr. Elizabeth Ann Esterl, RN October 10, 2017

14-May-04 THE EFFECT OF EXERCISE ON THE DEVELOPMENT OF HYPOGLYCEMIA IN CHILDREN WITH TYPE 1 DIABETES 14-May-04 SEVERE PEDIATRIC OPHTHALMIC TRAUMA SECONDARY TO GOLF- RELATED INJURY 18-May-04 ASSESSMENT OF INDUCED SPUTUM AS A TOOL TO EVALUATE ANTI- INFLAMMATORY AGENTS IN PATIENTS WITH CYSTIC FIBROSIS 18-May-04 A PROSPECTIVE STUDY TO EVALUATE AND DETERMINE THE EFFICACY OF A BOWEL AND BLADDER TREATMENT PROGRAM FOR PATIENTS WITH DYSFUNCTIONAL ELIMINATION SYNDROME 25-May-04 DNA EXTRACTION FOR COLORADO SUBJECTS WITH AUTISM 01-Jun-04 DIASTOLIC DYSFUNCTION IN MARFAN'S SYNDROME IN CHILDREN AND YOUNG ADULTS 04-Jun-04 OUTCOME OF HEART TRANSPLANTATION FOR HYPOPLASTIC LEFT HEART SYNDROME 04-Jun-04 SINGLE BREATH CARDIAC OUTPUT DETERMINATION DURING EXERCISE IN INDIVIDUALS WITH AND WITHOUT HEART DISEASE 08-Jun-04 PILOT STUDY OF VEGF AND ENOS POLYMORPHISMS IN NEONATES AT RISK FOR BRONCHOPULMONARY DYSPLASIA 24-Jun-04 TIME REDUCTION IN CLASSROOM ORIENTATION FOR NURSING STAFF FOLLOWING THE IMPLEMENTATION OF A BLENDED LEARNING FORMAT (INSTRUCTOR-LED AND ONLINE LEARNING MODULES). 02-Jul-04 UNILATERAL ABSENT PULMONARY ARTERY: SURGICAL RECONSTRUCTION AND LONG-TERM FOLLOW-UP 07-Jul-04 A PROSPECTIVE OBSERVATIONAL STUDY OF AIRWAY MANAGEMENT BY PRE-HOSPITAL PROVIDERS WHO TRANSPORT PATIENTS TO A DENVER METRO HOSPITAL 16-Jul-04 EXPLORING THE EXPERIENCES OF PEDIATRIC ONCOLOGY PATIENTS IN THE YOUTH AND PETS SURVIVORS PROGRAM (YAPS) 21-Jul-04 EARLY EXPERIENCE WITH LAPAROSCOPIC PLYOROMYOTOMY IN A TEACHING INSTITUTION 27-Jul-04 RETROSPECTIVE CHART REVIEW OF COMPLICATIONS OF INFLUENZA IN THE PICU 28-Jul-04 TRANSITION FOR YOUTH WITH SPECIAL HEALTH CARE NEEDS FROM PEDIATRIC TO ADULT ORIENTED CARE 03-Aug-04 PROTOCOL NUMBER: C200-002 A PLACEBO-CONTROLLED STUDY TO EALUATE THE SAFETY AND PILOT EFFICACY OF ILOPROST INHALATION SOLUTIONS AS ADD-ON THERAPY WITH BOSENTAN IN SUBJECTS WITH PULMONARY ARTERIAL HYPERTENSION. 12-Aug-04 SINGLE DOSE ESCALATION STUDY TO EVALUATE SAFETY OF NASAL ADMINISTRATION OF CFTR001 GENE TRANSFER VECTOR TO SUBJECTS WITH CYSTIC FIBROSIS 16-Aug-04 A MULTICENTER, EPIDEMIOLOGICAL, OBSERVATIONAL SURVEY OF THE MANAGEMENT OF ANEMIA IN CRITICALLY ILL PEDIATRIC PATIENTS

47 Dr. Elizabeth Ann Esterl, RN October 10, 2017

16-Aug-04 MULTICENTER PROSPECTIVE ANALYSIS OF PEDIATRIC SEDATION PRACTICE - THE PEDIATRIC SEDATION RESEARCH CONSORTIUM 17-Aug-04 PREMATURE LOSS OF THE PRIMARY MAXILLARY INCISORS: ITS EFFECTS ON MAXILLARY INTER-CANINE ARCH WIDTH 18-Aug-04 ANALYSIS OF FACTOR VIII AND D-DIMER LEVELS WITH RESPECT TO THROMBOTIC OUTCOMES IN CHILDREN (SUMMARY PER DOUG FORD REQUEST) 25-Aug-04 A RANDOMIZED CONTROLLED TRIAL OF THE SHOTBLOCKER FOR IMMUNIZATION INJECTION PAIN 25-Aug-04 LAPAROSCOPIC ASSISTED PERCUTANEOUS ENDOSCOPIC GASTROSTOMY IN CHILDREN AND ADOLESCENTS 25-Aug-04 A RANDOMIZED, DOUBLE-BLIND, PARALLEL-GROUP, MULTI-CENTER STUDY OF ALBUTEROL SULFATE HFA INHALATION AEROSOL DELIVERED CUMULATIVELY WITH A VALVED HOLDING CHAMBER AND AN ATTACHED FACEMASK IN SUBJECTS BETWEEN BIRTH TO 23 MONTHS OF AGE WITH ACUTE WHEEZING DUE TO OBSTRUCTIVE AIRWAYS DISEASE (SB030002) 26-Aug-04 PARENT AND FAMLIY CARE PROVIDER EXPERIENCES WITH PASTORAL CARE SUPPORT IN THE CONTEXT OF SHAKEN BABY SYNDROME 31-Aug-04 POSITIONING FOR THE NUSS PROCEDURE: AVOIDING BRACHIAL PLEXUS INJURIES 31-Aug-04 VERIFICATION OF THE GENEXPERT FOR LABORATORY DETECTION OF ENTEROVIRUS IN CLINICAL SPECIMENS 02-Sep-04 AEROBIC CAPACITY OF PHYSICIANS IN TRAINING PROGRAMS: THE FIT-DOC STUDY 14-Sep-04 THE EFFECTIVENESS OF PSOAS LENGTHENING AND PROXIMAL RECTUS FEMORIS RELEASES ON ANTERIOR PELVIC TILT AND HIP EXTENSION 14-Sep-04 LAPAROSCOPIC GUIDANCE OR REVISION OF VENTRICULOPERITONEAL SHUNTS 14-Sep-04 PRESERVATION OF AN ABERRANT LEFT HEPATIC ARTERY DURING LAPAROSCOPIC NISSEN FUNDOPLICATION. 22-Sep-04 OUTCOMES OF SUBMUCOSAL RESECTION VS RADIO FREQUENCY TISSUE ABLATION ON INFERIOR NASAL TURBINATES IN CHILDREN: A CHART REVIEW 27-Sep-04 COLLABORATIVE IMPROVEMENT OF NUTRITIONAL MANAGEMENT FOR CYSTIC FIBROSIS: THE MOUNTAIN WEST CYSTIC FIBROSIS CONSORTIUM 28-Sep-04 COMPARISON OF OUTCOMES IN CHILDREN WITH CEREBRAL PALSY WHEN THE RECOMMENDATIONS FROM GAIT ANALYSIS ARE OBSERVED 28-Sep-04 THERAPEUTIC RECOMMENDATIONS FOR CHILDREN WITH CEREBRAL PALSY: A COMPARISON BETWEEN RECOMMENDATIONS FOLLOWING COMPREHENSIVE GAIT ANALYSIS AND RECOMMENDATIONS USING CLINICAL DATA ONLY

48 Dr. Elizabeth Ann Esterl, RN October 10, 2017

28-Sep-04 PATHOLOGY AND IMAGING CORRELATION AND CLASSIFICATION FOR PEDIATRIC INTERSTITIAL LUNG DISEASE (PILD) 28-Sep-04 PACTG P1057: A PHASE I/II RANDOMIZED TRIAL OF THE SAFETY AND IMMUNOGENICITY OF COLD ADAPTED INFLUENZA VACCINE (FLUMIST™)IN HIV-INFECTED CHILDREN AND ADOLESCENTS 04-Oct-04 SURGICAL MANAGEMENT OF THE DUPLICATED KIDNEY: A REVIEW 06-Oct-04 THE NEUROPSYCHOLOGICAL DIFFERENCES BETWEEN A CONTROL GROUP OF PHYSICIANS AND PHYSICIANS REFERRED FOR COMPETENCY EVALUATIONS. 08-Oct-04 A PHASE II, OPEN-LABEL STUDY OF CLOFARABINE IN PEDIATRIC PATIENTS WITH REFRACTORY OR RELAPSED ACUTE LYMPHOBLASTIC LEUKEMIA 08-Oct-04 TELEPHONE TRIAGE PARENTAL PRIOR INTENT STUDY 08-Oct-04 STEM CELL CORRELATION STUDY OF HEMATOLOGY ANALYZERS VS. FLOW CYTOMETER: VALIDATION OF BECKMAN COULTER LH AND MAXM HEMATOLOGY ANALYZERS TO COUNT HEMOPOIETIC PROGENITOR CELL ( STEM CELLS ) WBCS 08-Oct-04 THE DETERMINATION OF ENCEPHALITIC EPIDEMIOLOGY WITHIN THE HOSPITALIZED POPULATION OF COLORADO DURING THE YEARS 1993 TO 2002. 12-Oct-04 GAIT ANALYSIS ALTERS DECISION MAKING IN THERAPEUTIC RECOMMENDATIONS FOR CHILDREN WITH CEREBRAL PALSY 12-Oct-04 INFLIXIMAB (REMICADE) FOR PATIENTS WITH ACUTE KAWASAKI DISEASE WHO FAIL TO BECOME AFEBRILE AFTER INTRAVENOUS GAMMA GLOBULIN THERAPY 12-Oct-04 PSYCHIATRIC DIAGNOSES IN PRESCHOOL CHILDREN WITH FETAL ALCOHOL SPECTRUM DISORDERS 25-Oct-04 REPETITIVE BEHAVIORS AND SENSORY PROFILES IN CHILDREN WITH AUTISM SPECTRUM DISORDERS AND DEVELOPMENTAL DISABILITIES (CHART REVIEW) 25-Oct-04 AALL01B1 - MULTIPARAMETER FLOW CYTOMETRY FOR ASSESSMENT OF EARLY MARROW RESPONSE IN PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA (ALL): A COMPANION STUDY TO CCG 1991 29-Oct-04 A MULTICENTER PHASE I TRIAL OF 17-N-ALLYLAMINO-17- DEMETHOXYGELDANAMYCIN (17-AAG, NSC#330507) IN PATIENTS WITH RECURRENT/REFRACTORY PEDIATRIC SOLID TUMORS (EWING'S SARCOMA, DESMOPLASTIC SMALL ROUND CELL TUMOR, OSTEOSARCOMA, NEUROBLASTOMA, AND RHABDOMYOSARCOMA) AND LEUKEMIA, NCI PROTOCOL NUMBER 6323 29-Oct-04 A PIVOTAL PHASE 3 STUDY OF MEDI-524 (NUMAX), AN ENHANCED POTENCY HUMANIZED RESPIRATORY SYNCYTIAL VIRUS (RSV) MONOCLONAL ANTIBODY, FOR THE PROPHYLAXIS OF SERIOUS RSV DISEASE IN HIGH-RISK CHILDREN 04-Nov-04 ALTERNATIVE INTERMITTENT CHEMOPROPHYLAXIS FOR PNEUMOCYSTIS CARINII IN PEDIATRIC LEUKEMIA AND LYMPHOMA PATIENTS, THE CHILDRENS HOSPITAL EXPERIENCE

49 Dr. Elizabeth Ann Esterl, RN October 10, 2017

05-Nov-04 NATIONAL SURVEILLANCE FOR EMERGING ADENOVIRUS INFECTIONS 12-Nov-04 A MULTICENTER, OPEN LABEL EXTENSION TO STUDY THE SAFETY OF TWICE DAILY ORAL CARVEDILOL IN PEDIATRIC PATIENTS WITH CHRONIC HEART FAILURE 16-Nov-04 ANTIMICROBIAL UTILIZATION IN THE NEONATAL INTENSIVE CARE UNIT 16-Nov-04 CRITERIA FOR TRACHEAL EXTUBATION OF PEDIATRIC LIVER TRANSPLANT PATIENTS IN THE OPERATING ROOM 16-Nov-04 A REVIEW OF PEDIATRIC PULMONARY HYPERTENSION PATIENTS UNDERGOING GENERAL ANESTHESIA 16-Nov-04 PENTOBARBITAL VERSUS PROPOFOL FOR SEDATION OF PEDIATRIC PATIENTS DURING RADIOLOGIC STUDIES 16-Nov-04 SEVOFLURANE AS THE SOLE ANESTHETIC FOR COMPUTED TOMOGRAPHY (CT) IMAGING 16-Nov-04 A PHASE II, MULTI-CENTER, OPEN-LABEL, REPEAT-DOSE STUDY OF FORODESINE HYDROCHLORIDE IN PATIENTS WITH ADVANCED T- CELL LEUKEMIA WITH AN OPTION OF LONG-TERM FORODESINE HYDROCHLORIDE USE 16-Nov-04 A 19-WEEK, RANDOMIZED, DOUBLE-BLIND, MULTICENTER, PLACEBO-CONTROLLED SAFETY STUDY TO EVALUATE THE COGNITIVE AND NEUROPSYCHOLOGICAL EFFECTS OF LEVETIRACETAM 20-60 MG/KG/DAY, DIVIDED IN TWICE DAILY DOSING, AS ADJUNCTIVE TREATMENT IN CHILDREN 4-16 YEARS OLD, INCLUSIVE, WITH PARTIAL ONSET SEIZURES. 16-Nov-04 FAMILY INFANT RELATIONSHIP SUPPORT TRAINING (FIRST): SUPPORTING INFANT-PARENT RELATIONSHIP DEVELOPMENT AFTER DISCHARGE FROM THE NICU 01-Dec-04 REVIEW OF KIDNEY STONES AND TREATMENT EFFECTIVENESS IN A PEDIATRIC POPULATION 03-Dec-04 LESSONS LEARNED IN ESTABLISHING A PEDIATRIC BOTOX CLINIC FOR TREATMENT OF HEADACHES 06-Dec-04 CORRELATIONSHIP OF IL-13RA MRNA EXPRESSION WITH CLINICAL PROGNOSTIC FACTORS IN EPENDYMOMA 06-Dec-04 EVALUATION FOR THE PRESENCE OF LYMPHOTROPIC POLYOMAVIRUS, SIMIAN VIRUS 40, JC VIRUS AND BK VIRUS IN LYMPHOBLASTS. 07-Dec-04 PERNIO IN PEDATRICS: A COLORADO EPIDEMIC? 07-Dec-04 FIVE-YEAR SAFETY SURVEILLANCE FOR "AN OPEN-LABEL TRIAL EVALUATING THE SAFETY AND EFFICACY OF TAMOXIFEN CITRATE (NOLVADEX) IN THE TREATMENT OF MCCUNE-ALBRIGHT SYNDROME" 07-Dec-04 A MULTI-CENTER, OPEN-LABEL, LONG-TERM, FOLLOW-UP STUDY OF THE SAFETY AND EFFICACY OF LEVETIRACETAM IN CHILDREN WITH PARTIAL ONSET SEIZURES: N01148 09-Dec-04 THE ASSESSMENT OF PAIN SENSATION DURING LOCAL ANESTHESIA

50 Dr. Elizabeth Ann Esterl, RN October 10, 2017

DELIVERY USING THE VIBRAJECT DENTAL SYRINGE ATTACHMENT VERSES A TRADITIONAL DENTAL INJECTION WHILE SHAKING THE LIP AS A FORM OF STIMULATION. 10-Dec-04 NEUROHORMONAL REGULATION OF ENERGY BALANCE AMONG PEDIATRIC BRAIN TUMOR SUBJECTS 10-Dec-04 DIRECTIGEN TM- EZ FLU A+B CLINICAL EVALUATION FOR DETECTION OF INFLUENZA A AND B: DRY SWAB EVALUATION (TRIAL NO.: 03C1-025-EZFLUD-CHD) 15-Dec-04 NURSES' PERCEPTIONS OF FEEDING INFANTS IN THE NICU AS ILLUSTRATED BY THEIR STORIES 15-Dec-04 PACTG 394, A PHASE I STUDY OF THE SAFETY, TOLERANCE, AND PHARMACOKINETICS OF TENOFOVIR DISOPROXIL FUMARATE (TDF) AND THE COMBINATION OF TDF PLUS EMTRICITABINE IN HIV-1 INFECTED PREGNANT WOMEN AND THEIR INFANTS 20-Dec-04 THE EFFECT OF RECTUS FEMORIS TRANSFER LOCATION ON CRITICAL KNEE JOINT KINEMATIC VALUES IN CHILDREN WITH CEREBRAL PALSY. 21-Dec-04 DEVELOPMENT OF A PEDIATRIC FELLOWSHIP TRAINING PROGRAM REPORT CARD 28-Dec-04 RETROSPECTIVE COMPARISON OF OUTCOMES IN ANTERIOR SPINE FUSION TECHNIQUE: THORACOTOMY VS. THORASCOPY 30-Dec-04 PARENTAL SURVEY OF CHILD'S POST-SEDATION, 24-HOUR RECOVERY 04-Jan-05 MARKETING FIELD EVALUATION OF NON-INVASIVE CRITSCAN HEMATOCRIT MEASUREMENT TECHNOLOGY 07-Jan-05 RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-1 (RHIGF-1) TREATMENT OF PREPUBERTAL CHILDREN WITH GROWTH FAILURE ASSOCIATED WITH PRIMARY IGF-1 DEFICIENCY: A PHASE 3, RANDOMIZED, OPEN-LABEL, OBSERVATION-CONTROLLED, MULTICENTER, PARALLEL-DOSE COMPARISON TRIAL (MS301) 13-Jan-05 SEDATION ASSESSMENT PRACTICES AMONG EXPERIENCED CICU NURSES 13-Jan-05 PARENT-CHILD CONFLICT, AUTONOMY AND DIABETES SELF-CARE, ANCILLARY TO THE TODAY STUDY 14-Jan-05 A RANDOMIZED, MULTICENTER, DOUBLE-BLIND TRIAL OF SANDOSTATIN LAR DEPOT (40MG) VERSUS SALINE-CONTROL IN THE TREATMENT OF PEDIATRIC HYPOTHALAMIC OBESITY 18-Jan-05 ACNS0122, A PHASE II STUDY TO ASSESS THE ABILITY OF NEOADJUVANT CHEMOTHERAPY +/- SECOND LOOK SURGERY TO ELIMINATE ALL MEASURABLE DISEASE PRIOR TO RADIOTHERAPY FOR NGGCT 18-Jan-05 AALL01P2 INTENSIVE INDUCTION THERAPY FOR CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) WHO EXPERIENCE A BONE MARROW RELAPSE 25-Jan-05 PILOT STUDY TO EVALUATE THE NAVIGATOR CONTINUOUS GLUCOSE SENSOR IN THE MANAGEMENT OF TYPE 1 DIABETES IN CHILDREN: A MULTICENTER TRIAL BEING CONDUCTED BY THE

51 Dr. Elizabeth Ann Esterl, RN October 10, 2017

DIABETES RESEARCH IN CHILDREN NETWORK 01-Feb-05 OBLIQUE PEDICLE SUBTRACTION OSTEOTOMY FOR THE TREATMENT OF CONGENITAL KYPHOSCOLIOSIS 08-Feb-05 A 6-WEEK, INTERNATIONAL, MULTICENTER, RANDOMIZED, DOUBLE- BLIND, PARALLEL-GROUP, PLACEBO-CONTROLLED, PHASE IIIB STUDY OF THE EFFICACY AND SAFETY OF QUETIAPINE FUMARATE (SEROQUEL) IMMEDIATE-RELEASE TABLETS IN DAILY DOSES OF 400 MG AND 800 MG COMPARED WITH PLACEBO IN THE TREATMENT OF ADOLESCENTS WITH SCHIZOPHRENIA 08-Feb-05 A 3-WEEK, RANDOMIZED, DOUBLE-BLIND, PARALLEL-GROUP, PLACEBO-CONTROLLED, PHASE IIIB STUDY OF THE EFFICACY AND SAFETY OF QUETIAPINE FUMARATE (SEROQUEL) IMMEDIATE- RELEASE TABLETS IN DAILY DOSES OF 400 MG AND 600 MG COMPARED WITH PLACEBO IN THE TREATMENT OF CHILDREN AND ADOLESCENTS WITH BIPOLAR I MANIA 08-Feb-05 A 26-WEEK, INTERNATIONAL, MULTICENTER, OPEN-LABEL PHASE IIIB STUDY OF THE SAFETY AND TOLERABILITY OF QUETIAPINE FUMARATE (SEROQUEL) IMMEDIATE-RELEASE TABLETS IN DAILY DOSES OF 400 MG TO 800 MG IN CHILDREN AND ADOLESCENTS WITH BIPOLAR I DISORDER AND ADOLESCENTS WITH SCHIZOPHRENIA 11-Feb-05 CHART REVIEW DESCRIBING/REGARDING THE EFFECT OF FENOLDOPAM ON MEAN ARTERIAL BLOOD PRESSURE AND URINE OUTPUT IN PEDIATRIC CARDIAC INTENSIVE CARE PATIENTS 11-Feb-05 OPERATIVE COMPLICATIONS IN CHILDREN WITH KAWASAKI SYNDROME 18-Feb-05 THROMBOTIC OUTCOMES AND UNDERLYING CONDITIONS IN LEMIERRE SYNDROME (THROMBOSIS OF THE JUGULAR VEIN IN ASSOCIATION WITH HEAD AND NECK INFECTION) IN CHILDREN: AN ANALYSIS OF DATA COLLECTED ON COMIRB PROTOCOLS 02-255 AND 03-368 18-Feb-05 PEDIATRIC DENTAL RAMIFICATIONS OF KAWASAKI SYNDROME 18-Feb-05 EVALUATION OF THE EFFECTIVENESS OF NURSING INITIATIVES ON PATIENT OUTCOMES: A RETROSPECTIVE STUDY 23-Feb-05 SENSORMEDICS VMAX ST: AGREEMENT WITH A BREATH-BY- BREATH METABOLIC SYSTEM 23-Feb-05 SHORT TERM CONSEQUENCES OF AN EDUCATIONAL CONFERENCE FOR THE MANAGEMENT OF PKU 25-Feb-05 YOUTH AND PET SURVIVORS PROGRAM: ASSESSING QUALITY OF LIFE AMONG PEDIATRIC ONCOLOGY PATIENTS USING THE PEDIATRIC ONCOLOGY QUALITY OF LIFE SCALE. 09-Mar-05 EVALUATION OF THE PROGRAM IN BIOETHICS AT THE CHILDREN'S HOSPITAL (PB@TCH) 16-Mar-05 ECHOCARDIOGRAPHIC ASSESSMENT OF AORTIC DIMENSIONS IN CHILDREN WITH ISOLATED BICUSPID AORTIC VALVE 16-Mar-05 THE ANALGESIC EFFICACY OF PREOPERATIVE HIGH DOSE (40 MG/KG) ORAL ACETAMINOPHEN DURING DENTAL PROCEDURES IN CHILDREN

52 Dr. Elizabeth Ann Esterl, RN October 10, 2017

21-Mar-05 A 12-WEEK, MULTI-CENTER EVALUATION OF THE MEDTRONIC MINIMED 407C INFUSION PUMP FOR DELIVERY OF INTRAVENOUS REMODULIN IN PEDIATRIC PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION 30-Mar-05 A MULTI-CENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO- CONTROLLED, 28-DAY STUDY OF DENUFOSOL TETRASODIUM (INS37217) INHALATION SOLUTION IN PATIENTS WITH CYSTIC FIBROSIS LUNG DISEASE 30-Mar-05 ACNS0231, A PHASE III RANDOMIZED TRIAL FOR THE TREATMENT OF PEDIATRIC HIGH GRADE GLIOMAS AT FIRST RECURRENCE WITH A SINGLE HIGH DOSE CHEMOTHERAPY AND AUTOLOGOUS STEM CELL TRANSPLANT VERSUS THREE COURSES OF INTERMEDIATE DOSE CHEMOTHERAPY WITH PERIPHERAL BLOOD STEM CELL (PBSC) 01-Apr-05 PREVALENCE OF PORTOPULMONARY HYPERTENSION AND HEPATOPULMONARY SYNDROME IN PEDIATRIC PATIENTS WITH PORTAL HYPERTENSION 06-Apr-05 AAML00P2, A DOSE FINDING STUDY OF THE SAFETY OF GEMTUZUMAB OZOGAMICIN COMBINED WITH CONVENTIONAL CHEMOTHERAPY FOR PATIENTS WITH RELAPSED, REFRACTORY, OR SECONDARY ACUTE MYELOID LEUKEMIA 06-Apr-05 RACIAL AND ETHNIC VARIATIONS IN LIFE COURSE DEVELOPMENT OF ADOLESCENT MOTHERS OVER A 2-YEAR INTERVAL FOLLOWING THE BIRTH OF THEIR FIRST CHILD 06-Apr-05 SATISFACTION WITH QUALITY OF LIFE IN ADOLESCENT CARDIAC TRANSPLANT RECIPIENTS. 06-Apr-05 AN EXAMINATION OF PSYCHIATRIC TREATMENT'S INFLUENCE ON THE HELP SEEKING ATTITUDES OF CHILDREN AND ADOLESCENTS 08-Apr-05 POST OPERATIVE COMPLICATIONS AND RISK FOR RE-TREATMENT WITH PAN RETINAL LASER PHOTOCOAGULATION FOR RETINOPATHY OF PREMATURITY 12-Apr-05 ADVL0421, A PHASE II STUDY OF OXALIPLATIN IN CHILDREN WITH RECURRENT SOLID TUMORS 15-Apr-05 THE EFFECT OF RECTUS FEMORIS WITH AND WITHOUT CONCOMITANT HAMSTRING LENGTHENING AT THE HIP AND PELVIS IN CHILDREN WITH CEREBRAL PALSY 20-Apr-05 A PHASE 3, DOUBLE-BLIND, MULTICENTER, RANDOMIZED, PLACEBO- CONTROLLED TRIAL WITH AZTREONAM LYSINATE FOR INHALATION IN CYSTIC FIBROSIS PATIENTS WITH PULMONARY P. AERUGINOSA REQUIRING FREQUENT ANTIBIOTICS (AIR CF2) PROTOCOL CP-AI-005. 20-Apr-05 RETROSPECTIVE CHART REVIEW OF TREATMENTS FOR PEDIATRIC URETERAL REFLUX FROM 1990 TO PRESENT. 22-Apr-05 PATTERN OF AORTIC ROOT DILATION IN MARFAN SYNDROME VERSUS BICUSPID AORTIC VALVE 22-Apr-05 LAPSE OF CARE AS A PREDICTOR FOR MORBIDITY IN ADULTS WITH CONGENITAL HEART DISEASE 27-Apr-05 A GROUP INTERVENTION FOR EXECUTIVE FUNCTION PROBLEMS IN ADOLESCENTS WITH TRAUMATIC BRAIN INJURY

53 Dr. Elizabeth Ann Esterl, RN October 10, 2017

28-Apr-05 A PILOT STUDY OF THE SAFETY OF ORAL HIGH FREQUENCY OSCILLATION FOR AIRWAY SECRETION CLEARANCE IN CYSTIC FIBROSIS. 04-May-05 PHASE I STUDY OF ERBITUX (CETUXIMAB) IN PEDIATRIC SUBJECTS WITH REFRACTORY SOLID TUMORS: CHARACTERIZATION OF SERUM PHARMACOKINETICS, SAFETY, AND EFFICACY FOLLOWING SINGLE DOSES AND REPEATED DOSES ADMINISTRATION WHEN COMBINED WITH IRINOTECA 05-May-05 EFFECT OF AGE AND SEDATIVE AGENT ON BISPECTRAL INDEX (BIS) AND DEPTH OF SEDATION IN CHILDREN 05-May-05 FORMOCRESOL BLOOD LEVELS DURING AND AFTER PULPOTOMY IN PRESCHOOL CHILDREN UNDERGOING COMPREHENSIVE ORAL REHABILITATION UNDER GENERAL ANESTHESIA 13-May-05 RESULTS OF SPINE DEFORMITY CORRECTION IN PATIENTS WITH MYELOMENINGOCELE 13-May-05 DIVALPROEX SODIUM EXTENDED-RELEASE TABLETS FOR MIGRAINE PROPHYLAXIS IN ADOLESCENTS: AN OPEN-LABEL, LONG-TERM SAFETY STUDY. PROTOCOL #: M03-648 SPONSOR: ABBOTT LABORATORIES 20-May-05 MULTINATIONAL, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY, COMPARATIVE STUDY TO EVALUATE THE EFFICACY AND SAFETY OF TELITHROMYCIN 25MG/KG GIVEN ONCE DAILY FOR 5 OR 10 DAYS DEPENDING ON AGE AND PREVIOUS TREATMENT HISTORY VERSUS CEFUROXIME AXETIL 15 MG/KG, GIVEN TWICE DAILY FOR 10 DAYS, IN CHILDREN WITH ACUTE OTITIS MEDIA (HMR3647B/3001) 20-May-05 NEURODEVELOPMENTAL DISORDERS AND PSYCHOPHARMACOLOGY IN PATIENTS WITH SEX CHROMSOME ANEUPLOIDY 25-May-05 PRACTICE PATTERNS AND MEDICAL MANAGEMENT OF CARCINOID TUMORS WITH OR WITHOUT CARCINOID SYNDROME: A CHART REVIEW OF 500 PATIENTS 27-May-05 IDURONATE-2-SULFATASE ENZYME REPLACEMENT THERAPY IN MUCOPOLYSACCHARIDOSIS II (MPSII); TKT CLINICAL PROTOCOL NO. TKT024EXT 31-May-05 AGCT01P1, PILOT STUDY OF CISPLATIN, ETOPOSIDE, BLEOMYCIN AND ESCALATING DOSE CYCLOPHOSPHAMIDE THERAPY FOR CHILDREN WITH HIGH-RISK MALIGNANT GERM CELL TUMORS 06-Jun-05 A MULTI-CENTER, OPEN-LABEL, ACTIVE-CONTROLLED, DOSE- TITRATION STUDY EVALUATING THE SAFETY, EFFICACY AND PHARMACOKINETICS OF OXYBUTYNIN TRANSDERMAL SYSTEMS IN THE TREATMENT OF DETRUSOR OVERACTIVITY ASSOCIATED WITH A NEUROLOGICAL CONDITION IN PEDIATRIC PATIENTS, FOLLOWED BY A 12-WEEK OPEN-LABEL SAFETY EXTENSION STUDY 07-Jun-05 THE EFFECTS OF LIMITED ENGLISH PROFICIENCY ON PATIENT SATISFACTION 13-Jun-05 ANALYSIS OF MRNA ALTERNATIVE SPLICE VARIANTS IN CHILDHOOD LEUKEMIA: POTENTIAL FOR DIAGNOSTICS 13-Jun-05 UNDERSTANDING THE MOLECULAR BIOLOGY OF CONGENITAL NEVI 13-Jun-05 PERIPHERAL BLOOD MONONUCLEAR CELL GENE EXPRESSION IN

54 Dr. Elizabeth Ann Esterl, RN October 10, 2017

RESPONSE TO TREATMENT OF CYSTIC FIBROSIS 17-Jun-05 THREONINE AND LYSINE REQUIREMENTS FOR OPTIMAL PROTEIN ANABOLISM IN NEONATES-A PILOT STUDY 17-Jun-05 A RETROSPECTIVE STUDY OF ORAL SEDATION REGIMENS USED IN PEDIATRIC DENTISTRY 21-Jun-05 CLINICAL TRIAL OF THE GENEXPERT ENTEROVIRUS ASSAY FOR DETECTION OF ENTEROVIRUS IN CEREBROSPINAL FLUID 28-Jun-05 PLATELET AGGREGATION INHIBITION IN CHILDREN ON CLOPIDOGREL (PICOLO); DOSE-RANGING PHARMACODYNAMIC ASSESSMENT OF PLATELET AGGREGATION INHIBITION WITH CLOPIDOGREL IN CHILDREN OF BLALOCK-TAUSSIG SHUNT AGE CATEGORIES (NEONATE AND INFANTS/TODDLERS) STUDY NO: PDY4422-FINAL PROTOCOL VERSION DATE 16, DECEMBER 2002 AND INCLUDING AMENDMENT 1 DATE 09 MAY 2003 AND AMENDMENT 2 DATED 02 APRIL 2004. 28-Jun-05 EVALUATION OF AN ACUITY SYSTEM AND NURSING WORKLOAD 19-Jul-05 A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, 28-DAY STUDY OF DENUFOSOL TETRASODIUM (INS37217) INHALATION SOLUTION IN PEDIATRIC PATIENTS WITH CYSTIC FIBROSIS LUNG DISEASE 22-Jul-05 THE RELATIONSHIP OF ILIOTIBIAL BAND LENGTH AND GLUTEUS MEDIUS STRENGTH IN SUBJECTS WITH PATELLOFEMORAL PAIN AND TREATMENT IMPLICATIONS 26-Jul-05 A MULTI-CENTER PHASE IB STUDY OF OXALIPLATIN (NCS#266046) IN COMBINATION WITH FLUOROURACIL AND LEUCOVORIN IN PEDIATRIC PATIENTS WITH ADVANCED SOLID TUMORS 26-Jul-05 APHAKIC GLAUCOMA AND TREATMENT WITH ENDOLASER CYCLOPHOTOCOAGULAION-THE CHILDREN'S HOSPITAL OF DENVER EXPERIENCE 27-Jul-05 ASCENSION PIP 27-Jul-05 A CASE SERIES OF CHILDREN WITH COLPOCEPHALY AND ITS AFFECT ON THE VISUAL SYSTEM. 02-Aug-05 POST-CONTRAST DELAYED MYOCARDIAL ENHANCEMENT PATTERNS IN CONGENITAL HEART DISEASE 02-Aug-05 THE LUPUS ANTICOAGULANT AND THROMBOTIC OUTCOMES IN CHILDREN: AN ANALYSIS OF DATA COLLECTED UNDER COMIRB PROTOCOLS #02-255 AND #03-368 02-Aug-05 THE ASSOCIATION OF THROMBOPHILIC TRAITS WITH PERINATAL THROMBOSIS: AN ANALYSIS OF DATA COLLECTED UNDER COMIRB PROTOCOLS #02-255 AND #03-368. 05-Aug-05 ASSESSMENT OF AORTIC WALL COMPLIANCE IN PATIENTS WITH BICUSPID AORTIC VALVE AND COARCTATION OF THE AORTA BY TISSUE DOPPLER 05-Aug-05 A MULTICENTER, OPEN-LABEL, SINGLE-ARM, TWO-STEP STUDY TO EVALUATE THE SAFETY AND SINGLE-DOSE PHARMACOKINETICS OF FAMCICLOVIR AND MULTIPLE-DOSE SAFETY AFTER ADMINISTRATION OF FAMCICLOVIR ORAL PEDIATRIC

55 Dr. Elizabeth Ann Esterl, RN October 10, 2017

FORMULATION TO CHILDREN 1 TO 18 YEARS OF AGE WITH HERPES SIMPLEX INFECTION 05-Aug-05 A PHASE II STUDY OF CAMPATH-1H IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA IN SECOND OR REFRACTORY RELAPSE 05-Aug-05 NITRIC OXIDE METABOLISM IN STATIN-TREATED PEDIATRIC SLE 09-Aug-05 AN OPEN-LABEL MULTICENTER STUDY OF THE LONG-TERM SAFETY OF DEPAKOTE SPRINKLE CAPSULES IN THE TREATMENT OF PARTIAL SEIZURES IN CHILDREN. CLINICAL PROTOCOL M04-714 SPONSOR- ABBOTT LABORATORIES 12-Aug-05 A PHASE III RANDOMIZED, DOUBLE-BLIND TRIAL COMPARING HSPE7 AND PLACEBO IN THE TREATMENT OF CHILDREN AND YOUNG ADULTS WITH RECURRENT RESPIRATORY PAPILLOMATOSIS REQUIRING FREQUENT DEBULKING SURGERIES PROTOCOL NUMBER: SGN-00101-0401 12-Aug-05 PULMONARY HYPERTENSION AND SICKLE CELL DISEASE 25-Aug-05 FEEDING PATTERS OF INFANTS AND TODDLERS WITH BRAIN INJURIES DUE TO CHILD ABUSE 26-Aug-05 COARCTATION OF THE AORTA PRESENTING WITH SEVERE LEFT VENTRICULAR DYSFUNCTION 26-Aug-05 THE RELATION BETWEEN CHILDHOOD WORKING MEMORY PERFORMANCE AND PARENT REPORT OF EXECUTIVE FUNCTIONING FOLLOWING TRAUMATIC AND ACQUIRED BRAIN INJURY. 30-Aug-05 FOLLOW-UP STUDY OF ADULT MALES WITH FRAGILE X SYNDROME: QUALITY OF LIFE, SUPPORTS AND SERVICES 06-Sep-05 DIET RECORDS: ARE PICTURES REALLY WORTH A THOUSAND WORDS? 07-Sep-05 REMICADE (INFLIXIMAB) INFUSIONS AND VITAL SIGN MONITORING 14-Sep-05 THE INCEDENCE OF PATIENTS WHO ARE GIVEN A PRESCRIPTION BUT DISPENSED THE WRONG GLASSES 15-Sep-05 ESTABLISHING THE ETIOLOGY OF CHILDHOOD HEARING LOSS BY ROUTINE CLINICAL, LABORATORY, AND IMAGING TECHNIQUES 16-Sep-05 A PHASE 3, OPEN-LABEL, FOLLOW-ON STUDY OF MULTIPLE COURSES OF AZTREONAM LYSINATE FOR INHALATION (AI) IN CYSTIC FIBROSIS PATIENTS (AIR-CF3) 28-Sep-05 SUBCUTANEOUS GLUCAGON AS A SIMPLE AND EFFICIENT MEANS OF ASSESSING THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS IN CHILDREN 29-Sep-05 OUTCOMES ASSOCIATED WITH OFF-LABEL USE OF RECOMBINANT FACTOR VIIA IN CHILDREN. 30-Sep-05 CORRELATION BETWEEN DISTANCE WALKED IN SIX-MINUTES AND MEASURES OF PULMONARY FUNCTION IN CYSTIC FIBROSIS 30-Sep-05 THE IMPACT OF MISSING INFORMATION AT PEDIATRIC EMERGENCY AND OUTPATIENT CLINIC VISITS 30-Sep-05 TOTAL PARENTERAL NUTRITION PRIOR TO LIVER TRANSPLANT IN INFANTS WITH BILIARY ATRESIA

56 Dr. Elizabeth Ann Esterl, RN October 10, 2017

10-Oct-05 A RETROSPECTIVE REVIEW OF THE USES FOR BOTULINUM TOXIN TYPE A AND B IN A PEDIATRIC HOSPITAL 14-Oct-05 A STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND IMMUNOGENICITY OF MEDI-524, A HUMANIZED ENHANCED POTENCY MONOCLONAL ANTIBODY AGAINST RESPIRATORY SYNCYTIAL VIRUS (RSV), IN CHILDREN WITH HEMODYNAMICALLY SIGNIFICANT CONGENITAL HEART DISEASE 20-Oct-05 EVALUATION OF PERCEPTIONS, KNOWLEDGE, AND AWARENESS OF ITS EFFECTIVENESS HELD BY PEDIATRIC HEALTH CARE PROVIDERS ON AAPD BEHAVIOR MANAGEMENT TECHNIQUES 21-Oct-05 USING MEDICAL CHART REVIEW TO VALIDATE AN ELECTRONIC ANTIBIOTIC CLASSIFICATION SYSTEM 25-Oct-05 AN OPEN LABEL, MULTICENTER STUDY TO ASSESS THE PHARMACOKINETICS, TOLERABILITY, AND SAFETY OF A PEDIATRIC FORMULATION OF BOSENTAN IN CHILDREN WITH IDIOPATHIC OR FAMILIAL PULMONARY ARTERIAL HYPERTENSION PROTOCOL: FUTURE 1 AC-052-365 28-Oct-05 TOPMAT-PEP-3001: A RANDOMIZED, DOUBLE-BLIND,PLACEBO- CONTROLLED,FIXED-DOSE RANGING STUDY TO ASSESS THE SAFETY, TOLERABILITY, AND EFFICACY OF TOPIRAMATE ORAL LIQUID AND SPRINKLE FORMULATIONS AS AN ADJUNCT TO CONCURRENT ANTICONVULSANT THERAPY FOR INFANTS (1-24 MONTHS OF AGE,INCLUSIVE) WITH REFRACTORY PARTIAL ONSET SEIZURES, WITH OPEN-LABEL EXTENSION 04-Nov-05 A STUDY OF THE SAFETY AND PHARMACOKINETICS OF 552-02 FOLLOWING FOURTEEN DAYS OF DOSING BY INHALATION IN PATIENTS WITH CYSTIC FIBROSIS 04-Nov-05 RETROSPECTIVE ANALYSIS OF VALVED HOMOGRAFT SHORT-TERM PERFORMANCE: A COMPARISON OF SYNERGRAFT® DECELLULARIZED GRAFTS TO NORMAL CRYO-PRESERVED CRYOVALVE® GRAFTS 06-Nov-05 MEASURING NURSES' INDIVIDUAL PERCEPTION OF WORKLOAD USING THE INDIVIDUAL WORKLOAD PERCEPTION SCALE (IWPS) 06-Nov-05 EFFECT OF SILDENAFIL THERAPY ON CHILDHOOD PULMONARY ARTERIAL HYPERTENSION 10-Nov-05 PHARMACOGENOMICS OF PULMONARY ARTERIAL HYPERTENSION 10-Nov-05 PEDIATRIC HOSPITALIST CO-MANAGEMENT OF SPINE FUSION SURGERIES: THE EXPERIENCE AT THE CHILDRENS' HOSPITAL 15-Nov-05 INCIDENCE OF COMMUNITY-ACQUIRED METHICILLIN-RESISTANT STAPHYLOCCUS AUREUS HEAD AND NECK INFECTIONS IN A PEDIATRIC POPULATION 21-Nov-05 STEREOTACTIC RADIOSURGERY AS A CURATIVE ADJUNCT IN INCOMPLETELY RESECTED RECURRENT EPENDYMOMA 21-Nov-05 HUMAN METAPNEUMOVIRUS (HMPV) LOWER RESPIRATORY TRACT INFECTION IN CHILDREN: CLINICAL VALIDATION OF AN HMPV PCR AND DETERMINATION OF RISK FACTORS FOR SEVERE HMPV INFECTION

57 Dr. Elizabeth Ann Esterl, RN October 10, 2017

01-Dec-05 KNOWLEDGE OF NOCSAE HELMET STANDARD AMONG HIGH SCHOOL LACROSSE COACHES. 16-Dec-05 A PHASE I/II, MULTI-CENTER, OPEN-LABEL, REPEAT-DOSE STUDY OF FORODESINE HYDROCHLORIDE INFUSION IN PATIENTS WITH B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA WITH AN OPTION OF EXTENDED USE OF FORODESINE HYDROCHLORIDE 30-Dec-05 ENVIRONMENTAL FACTORS AND BILIARY ATRESIA 05-Jan-06 ANESTHETIC CHALLENGES AND COMPLICATIONS ASSOCIATED WITH RADIATION THERAPY AT AN OFFSITE HOSPITAL 06-Jan-06 MULTI-CENTER STUDY ON THE INCIDENCE OF INTRA-OPERATIVE AWARENESS AND RECALL IN THE PEDIATRIC POPULATION UNDERGOING GENERAL ANESTHESIA: CARE - CHILDHOOD AWARENESS AND RECALL EVALUATION 13-Jan-06 INVASIVE PNEUMOCOCCAL INFECTION AND THE FREQUENCY OF RENAL DYSFUNCTION, INCLUDING HEMOLYTIC UREMIC SYNDROME. A 5 YEAR RETROSPECTIVE ANALYSIS. 25-Jan-06 INCIDENCE OF RECURRENT DECAY FOLLOWING DENTAL REHABILITATION UNDER GENERAL ANESTHESIA, A CHART REVIEW OF 100 CASES. 25-Jan-06 INCIDENCE OF NEW DECAY FOLLOWING DENTAL REHABILITATION WITH CONSCIOUS SEDATION, A CHART REVIEW OF 50 CASES. 25-Jan-06 PARENTAL KNOWLEDGE AND EXPECTATIONS OF ORAL REHYDRATION THEARAPY (ORT) IN CHILDREN WITH MILD TO MODERATE DEHYDRATION 26-Jan-06 RESIDENCY TRAINING IN CHILD MALTREATMENT: A NATIONAL STUDY OF RESIDENTS AND PROGRAM DIRECTORS 07-Feb-06 CORRELATION OF ABDOMINAL OXIMETER MONITORING WITH GASTRIC TONOMETRY AS A MEASUREMENT OF SPLANCHNIC AND RENAL PERFUSION IN INFANTS WITH CONGENITAL CYANOTIC HEART DISEASE 07-Feb-06 PACTG P1059: PHASE I, OPEN-LABEL STUDY TO EVALUATE THE SAFETY AND TOLERABILITY OF RECOMBINANT HIV-1 VACCINES IN HIV-1 INFECTED YOUNG ADULTS WITH CONTROL OF HIV-1 REPLICATION AND ON STABLE HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART) 12-Feb-06 THE EFFECTIVENESS OF STAFF NURSE INTERVIEW COMMITTEE ON RETENTION/RECRUITMENT OF REGISTERED NURSES 14-Feb-06 LONG-TERM, OPEN-LABEL SAFETY STUDY OF ORAL ALMOTRIPTAN MALATE 12.5 MG IN THE TREATMENT OF MIGRAINE IN ADOLESCENTS (PROTOCOL CAPSS-368; PHASE IIIB) 22-Feb-06 A DOUBLE-BLIND, RANDOMIZED, VEHICLE-CONTROLLED TRIAL TO DETERMINE THE EFFICACY AND SAFETY OF LOCOID LIPOCREAM (HYDROCORTISONE BUTYRATE 0.1%) CREAM IN THE TREATMENT OF MILD TO MODERATE ATOPIC DERMATITIS IN PEDIATRIC SUBJECTS, PROTOCOL 04-110 24-Feb-06 OUTCOMES OF PROXIMAL FEMORAL RESECTION FOR HIP IN CEREBRAL PALSY

58 Dr. Elizabeth Ann Esterl, RN October 10, 2017

15-Mar-06 EFFECT OF EDUCATION ON PARENTAL ATTITUDES AND KNOWLEDGE REGARDING CT RADIATION. 22-Mar-06 A RETROSPECTIVE CHART REVIEW TO ASSESS THE SAFETY OF OSELTAMIVIR (TAMIFLU) COMPARED TO ALTERNATE ANTIVIRAL THERAPY (AMANTADINE OR RIMANTADINE) ADMINISTERED TO CHILDREN LESS THAN 12 MONTHS OF AGE WITH DIAGNOSED OR SUSPECTED INFLUENZA (CASG 113) 28-Mar-06 AN ONGOING EVALULATION OF THE SAFETY AND EFFICACY OF THE CARDIOSEL SEPTAL OCCLUSION SYSTEM WITH QWIK LOAD IN PATIENTS WITH VENTRICULAR SEPTAL DEFECT ("POST-MARKET VSD FOLLOW-UP REGISTRY") 28-Mar-06 FAMIY PRESENCE DURING RESUSCITATIVE EFFORTS IN A PEDIATRIC EMERGENCY DEPARTMENT 14-Apr-06 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE III STUDY OF THE PHOSPHODIESTERASE TYPE 5 (PDE5) INHIBITOR TADALAFIL IN THE TREATMENT OF PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION (PROTOCOL LVGY) 14-Apr-06 A PROSPECTIVE STUDY OF SURGICAL PROCEDURES FOR THE TREATMENT OF PERSISTENT NASOLACRIMAL DUCT OBSTRUCTION IN CHILDREN LESS THAN FOUR YEARS OLD 19-Apr-06 MEDIASTINITIS IN CHILDREN AFTER HEART SURGERY 22-Apr-06 ANGIOGENESIS OF AORTOPULMONARY COLLATERAL VESSELS IN SINGLE VENTRICLE PHYSIOLOGY 22-Apr-06 MOUNTAIN STATES GENETICS NETWORK REGIONAL COLLABORATIVE CENTER SMALL GRANT PROGRAM NATURAL HISTORY OF RECOMBINANT 8 SYNDROME 25-Apr-06 HEALTHY PEOPLE 2010 OBJECTIVES FOR A HEALTHY WORKFORCE: AN EVALUATION OF EMPLOYEE WELLNESS PROGRAMS IN METRO DENVER 26-Apr-06 A RANDOMIZED, ASSESSOR-BLIND, DOSE-RANGING, PHASE IIIB, MULTICENTER TRIAL COMPARING THE INTUBATING CONDITIONS AND TIME COURSE OF BLOCK OF THREE DIFFERENT INTUBATING DOSES (0.45MG/KG, 0.6MG/KG, AND 1.0MG/KG) OF ZEMURON IN PEDIATRIC AND ADOLESCENT SUBJECTS UNDER GENERAL ANESTHESIA 26-Apr-06 VERIFICATION OF A MONOCLONAL ANTIBODY FOR RAPID DETECTION OF HUMAN METAPNEUMOVIRUS (HMPV) BY DIRECT IMMUNOFLUORESCENCE AND CULTURE 26-Apr-06 CURRENT TRENDS IN VENTRICULAR SEPTAL DEFECT MANAGEMENT. 28-Apr-06 PO2095 OPEN LABEL, LIMITED ACCESS PROTOCOL OF POSACONAZOLE IN INVASIVE FUNGAL INFECTIONS 28-Apr-06 CLINICAL OUTCOMES OF PATIENTS IMPLANTED WITH A VAGUS NERVE STIMULATOR (VNS) AT THE CHILDREN'S HOSPITAL, DENVER. 03-May-06 PNEUMOCOCCAL VACCINE AND HOSPITALIZATION RATES IN COLORADO AND NATIONALLY 08-May-06 A DOUBLE-BLIND EXTENSION STUDY TO EVALUATE THE LONG- TERM SAFETY AND EFFICACY OF THE PHOSPHODIESTERASE TYPE 5

59 Dr. Elizabeth Ann Esterl, RN October 10, 2017

(PDE5) INHIBITOR TADALAFIL IN THE TREATMENT OF PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION; PROTOCOL LVGX 12-May-06 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP STUDY, CONDUCTED UNDER IN-HOUSE BLINDING CONDITIONS, TO EXAMINE THE SAFETY, TOLERABILITY, AND EFFICACY OF APREPITANT FOR THE PREVENTION OF CHEMOTHERAPY-INDUCED NAUSEA AND VOMITING ASSOCIATED WITH EMETOGENIC CHEMOTHERAPY IN ADOLESCENT PATIENTS. 12-May-06 DESIRED COMPETENCIES OF FUTURE HEALTHCARE PROFESSIONALS: PERSPECTIVES FROM ADMINISTRATORS, CLINICAL STAFF, PARENTS AND PATIENTS. 07-Jun-06 C-05-36: SAFETY AND EFFICACY EVALUATION OF TOPICAL MOXIDEX OTIC SOLUTION COMPARED TO MOXIFLOXACIN SOLUTION IN THE TREATMENT OF ACUTE OTITIS MEDIA WITH OTORRHEA THROUGH TYMPANOSTOMY TUBES (AOMT) 09-Jun-06 CORRELATION BETWEEN PHYSICAL EXAMINATION FINDINGS OF SPASTICITY AND KINEMATIC DATA DURING GAIT LABORATORY ANALYSIS IN CHILDREN WITH CEREBRAL PALSY 12-Jun-06 NURSES' PERCEPTIONS OF ORGANIZATIONAL RELOCATION 07-Jul-06 SAFETY AND EFFICACY OF INHALED ILOPROST IN PEDIATRIC PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION PROTOCOL NUMBER- C200-007 07-Jul-06 PEDIATRIC SPINAL CORD TUMORS AND FUNCTIONAL OUTCOMES 08-Aug-06 VOCAL CORD PARALYSIS AFTER PEDIATRIC CARDIAC SURGERY 22-Aug-06 A RANDOMIZED, SINGLE-BLIND, DOSE-RISING, PLACEBO- CONTROLLED, CROSSOVER STUDY TO EVALUATE THE PHARMACOKINETICS, PHARMACODYNAMICS, AND TOLERABILITY OF EXENATIDE IN ADOLESCENT SUBJECTS WITH TYPE 2 DIABETES MELLITUS 05-Sep-06 NURSE-PHYSICIAN RELATIONS 08-Sep-06 A FOUR WEEK, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE III TRIAL EVALUATING THE EFFICACY, SAFETY AND PHARMACOKINETICS OF FLEXIBLE DOSES OF ORAL ZIPRASIDONE IN CHILDREN AND ADOLESCENTS WITH BIPOLAR I DISORDER, (MANIC OR MIXED) 12-Sep-06 A PHASE II STUDY OF PENTOSTATIN FOR THE TREATMENT OF HIGH- RISK OR REFRACTORY CHRONIC GVHD IN CHILDREN 20-Sep-06 SAFETY OF EMERGENCY DEPARTMENT PEDIATRIC PROCEDURAL SEDATION AND ANALGESIA 27-Sep-06 26-WEEK OPEN-LABEL EXTENSION STUDY EVALUATING THE SAFETY AND TOLERABILITY OF FLEXIBLE DOSES OF ORAL ZIPRASIDONE IN CHILDREN AND ADOLESCENTS WITH BIPOLAR I DISORDER (MANIC OR MIXED) 03-Oct-06 BK: A VIRUS ON THE RISE? 10-Oct-06 CRYOVALVE SG HUMAN PULMONARY VALVE FOLLOW-UP STUDY 12-Oct-06 THE BONE MARROW TRANSPLANT REUNION PICNIC: A

60 Dr. Elizabeth Ann Esterl, RN October 10, 2017

CELEBRATION AND REJUVENATION 24-Oct-06 ASSESSMENT OF PAIN SENSATION DURING LOCAL ANESTHESIA DELIVERY IN TRADITIONAL DENTAL INJECTIONS USING THE VIBRAJECT DENTAL SYRINGE ATTACHMENT VERSUS LIP SHAKING AS MEANS OF DISTRACTIVE STIMULATION. 28-Oct-06 BLADDER URINE CONCENTRATIONS OF TRANSFORMING GROWTH FACTOR-B1 IN CHILDREN WITH UPPER URINARY TRACT DILATATION. 28-Oct-06 A PROSPECTIVE, NON-INTERVENTIONAL STUDY TO EVALUATE THE INCIDENCE OF HOSPITALIZATIONS AND MEDICALLY ATTENDED LOWER RESPIRATORY TRACT INFECTION (MALRI) IN PREMATURE INFANTS 32 TO 35 WEEKS GESTATIONAL AGE WHO ARE NOT RECOMMENDED TO RECEIVE PROPHYLAXIS FOR RSV 03-Nov-06 A MULTI-CENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO- CONTROLLED, PARALLEL-GROUP STUDY WITH THREE FIXED DOSES OF ARIPIPRAZOLE IN THE TREATMENT OF CHILDREN AND ADOLESCENTS WITH AUTISTIC DISORDER 03-Nov-06 NATIONAL US INPATIENT HEALTHCARE FACILITY METHICILLIN- RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) SURVEY 10-Nov-06 A RANDOMIZED, MULTICENTER, DOUBLE-BLIND EXPLORATORY STUDY TO EVALUATE THE EFFICACY OF AN EXTENDED CYCLE COMBINATION ORAL CONTRACEPTIVE, DP3-84/10, WHICH UTILIZES ETHINYL ESTRADIOL DURING THE USUAL HORMONE-FREE INTERVAL, COMPARED TO PLACEBO FOR THE TREATMENT OF CYCLIC PELVIC PAIN IN ADOLESCENTS. PROTOCOL NUMBER: DR- PSE-306 12-Nov-06 EVALUATION OF QUETIAPINE USE IN AN INPATIENT PEDIATRIC POPULATION AT A TEACHING HOSPITAL. 15-Nov-06 EVALUATION OF A COMPUTER-BASED AND MOCK CODE CURRICULUM TO TEACH PEDIATRIC PHARMACISTS RESUSCITATION SKILLS. 17-Nov-06 DEPTH OF ANESTHESIA AND THE INCIDENCE OF EMERGENCE AGITATION AND POST-OPERATIVE BEHAVIORAL CHANGES IN A POPULATION OF PEDIATRIC DENTAL PATIENTS 01-Dec-06 A PHARMACOKINETIC STUDY OF UT-15C IN SUBJECTS WITH PULMONARY ARTERIAL HYPERTENSION (PROTOCOL TDE-PH-306) 01-Dec-06 DIURNAL VARIATIONS IN SALIVARY STEROIDS OF BIPOLAR ADOLESCENT PATIENTS RECEIVING PSYCHOEDUCATION 08-Dec-06 ORTHOPEDIC AND REHABILITATION MEDICINE ENCOUNTERS AFTER GAIT ANALYSIS STUDIES FOR CHILDREN WITH CEREBRAL PALSY 12-Jan-07 A PHASE 3, RANDOMIZED, OBSERVER-BLIND, CONTROLLED, MULTI- CENTER STUDY TO EVALUATE THE LOT TO LOT CONSISTENCY OF NOVARTIS MENINGOCOCCAL ACWY CONJUGATE VACCINE WHEN ONE DOSE IS ADMINISTERED TO HEALTHY ADOLESCENTS 11-18 YEARS OF AGE AND TO COMPARE THE SAFETY AND IMMUNOGENICITY OF NOVARTIS MENINGOCOCCAL ACWY CONJUGATE VACCINE WITH THAT OF LICENSED MENINGOCOCCAL ACWY CONJUGATE VACCINE (MENACTRA) WHEN ONE DOSE IS ADMINISTERED TO HEALTHY SUBJECTS 11-55 YEARS OF AGE

61 Dr. Elizabeth Ann Esterl, RN October 10, 2017

PROTOCOL V59P13 19-Jan-07 RISK OF ADVERSE EVENTS OR MENINGITIS IN FEBRILE INFANTS 28-60 DAYS OF LIFE WITH UTIS AND DERIVATION OF A CLINICAL DECISION RULE TO IDENTIFY INFANTS 28-60 DAYS OF LIFE WITH UTIS AT VERY LOW RISK OF BACTEREMIA, ADVERSE EVENTS OR MENINGITIS 25-Jan-07 EVALUATION OF A CLINICAL CARE GUIDELINE FOR THE PEDIATRIC APPENDECTOMY PATIENT 06-Mar-07 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTI- CENTER, CROSSOVER STUDY TO EVALUATE THE EFFECTIVENESS AND SAFETY OF PANCRECARB MS-16 (PANCRELIPASE) IN REDUCING STEATORRHEA IN CHILDREN AND ADULTS WITH CYSTIC FIBROSIS 06-Mar-07 MOTHERS AND TODDLERS 30-Mar-07 ARST0431 INTENSIVE MULTI-AGENT THERAPY, INCLUDING DOSE- COMPRESSED CYCLES OF IFOSFAMIDE/ETOPOSIDE (IE) AND VINCRISTINE/DOXORUBICIN/CYCLOPHOSPHAMIDE (VDC) FOR PATIENTS WITH HIGH-RISK RHABDOMYOSARCOMA 06-Apr-07 ANAKINRA FOR SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS 04-May-07 EFFECTS OF ETHANOL ON ESSENTIAL TREMOR PATIENTS WITH DEEP BRAIN STIMULATORS 16-May-07 OUTCOMES OF REPARATIVE AND TRANSPLANT TREATMENT STRATEGIES FOR CONGENITAL MITRAL STENOSIS WITH ASSOCIATED MULTILEVEL LEFT HEART OBSTRUCTIONS 16-May-07 PEDIATRIC ANTI-REFLUX SURGERY AT US HOSPITALS (2000-2006) 30-May-07 PRACTICE PATTERNS IN THE EVALUATION OF FEBRILE INFANTS (30 TO 90 DAYS) WITH FEVER DURING WINTERTIME 05-Jul-07 OUTCOMES OF PEDIATRIC MITRAL VALVE REPAIR AND REPLACEMENT 12-Jul-07 EPIDEMIOLOGIC MULTICENTER STUDY ON MECHANICAL VENTILATION MANAGEMENT IN CHILDREN WITH ACUTE LUNG INJURY 18-Jul-07 ASSESSMENT OF THE SINGLE DOSE PHARMACOKINETIC CHARACTERISTICS OF ZANAFLEX CAPSULES (TIZANIDINE HYDROCHLORIDE) AFTER A STANDARD MEAL IN CHILDREN WITH CLINICAL EVIDENCE OF SPASTICITY (AT06-ZC-02) 31-Aug-07 SURGICAL REPAIR OF SUPRAVALVULAR AORTIC STENOSIS AND OTHER CONGENITAL VASCULAR DEFECTS IN PATIENTS WITH WILLIAMS SYNDROME 04-Oct-07 THE LOCATION AND DENSITY OF FUNGAL COLONIZATION OF HEALTHCARE WORKERS AND THEIR PETS: A PRELIMINARY STUDY 10-Oct-07 SAPROPTERIN EXPANDED ACCESS PROGRAM - SEAP-001 22-Oct-07 LAPAROSCOPIC PLACEMENT OF DISTAL VENTRICULOPERITONEAL SHUNTS 26-Oct-07 RELIABILITY OF THE OXYCON MOBILE GAS ANALYZER DURING A 5- MINUTE WALK TEST 15-Nov-07 EFFECT OF SILDENAFIL THERAPY ON CHILDHOOD PULMONARY

62 Dr. Elizabeth Ann Esterl, RN October 10, 2017

HYPERTENSION 21-Nov-07 EVALUATION OF PROLONGED DEXMEDETOMIDINE (DEX, PRECEDEX (R)) INFUSIONS IN CRITICALLY ILL INFANTS AND CHILDREN. 29-Nov-07 RETROSPECTIVE EVALUATION OF ERTAPENEM IN PEDIATRIC PATIENTS WITH PERFORATED APPENDICITIS 30-Nov-07 A PHASE 1, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE ESCALATING STUDY TO EVALUATE THE SAFETY, TOLERABILITY, IMMUNOGENICITY, AND VIRAL SHEDDING OF MEDI- 534, A LIVE, ATTENUATED INTRANASAL VACCINE AGAINST RESPIRATORY SYNCYTIAL VIRUS (RSV) AND PARAINFLUENZA VIRUS TYPE 3 (PIV3) IN HEALTHY CHILDREN 6 TO <24 MONTHS OF AGE PROTOCOL NUMBER: MI-CP149 30-Nov-07 AN EXPANDED PHASE 1/2A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED STUDY TO EVALUATE THE SAFETY, TOLERABILITY, IMMUNOGENICITY, AND VIRAL SHEDDING OF MEDI-560, A LIVE, ATTENUATED RECOMBINANT PARAINFLUENZA VIRUS TYPE 3 (PIV3) VACCINE, ADMINISTERED INTRANASALLY TO HEALTHY INFANTS 1 TO <12 MONTHS OF AGE PROTOCOL NUMBER: MIC-CP150 02-Jan-08 BIOMARKERS OF LUNG INJURY AND REMODELING IN CHILDREN WITH CYSTIC FIBROSIS 01-June-13 PEDIATRIC IMMUNEDEFICIENCY RESEARCH DATABASE 01 Jan 1 03-Mar-14 REDUCING VARIABILITY AMONG MULTIPLE OPERATORS USING A SINGLE TECHNIQUE AND DEVICE FOR SKIN PRICK TESTING IN CHILDREN 04-Jan-15 EXERCISE DYSPNEA AND THE LARYNX STUDY

11-Nov-15 VALIDATION OF A RAPID MOLECULAR DIAGNOSTIC METHOD FOR MRSA/MSSA IN PEDIATRIC ATOPIC DERMATITIS PATIENTS 12-Dec-15 ROLE OF Cyp11a1 IN NON-ALLERGIC CHILDREN

14-Dec-15 THE UTILITY OF FOOD-SPECIFIC IGE MEASURED WITH THE IMMULITE 2000 ASSAY TO PREDICT SYMPTOMATIC FOOD ALLERGY (SIEMENS) 15-Dec-15 SENSITIVITY AND SPECIFICITY OF EXTRACTS MIXES VERSUS COMPONENTS DURING IMMEDIATE HYPERSENSITIVITY SKIN TEST IN PEDIATRIC 19-Jan-16 INTEGRATED BIOINFORMATION AND SPECIMEN CENTER- GENERAL PROTOCOL

Publications and Abstracts

1995 Esterl B. Immunological Disorders. Medfacts. National Jewish.

1995 Esterl B. Immune Deficiencies. Medfacts. National Jewish.

1996 Gelfand EW, Esterl B, and Mazer B. Benefit of a 12% solution of IVIG in the treatment of steroid-dependent asthma. In: Immunoglobulins: Extending the Horizon. Kazatchkine MD and Louwagie A, eds. Parthenon Publishing Group Ltd. (London, UK), pp.49-62, 1995.

1996 Gelfand EW, Landwehr LP, Esterl B, and Mazer B. Intravenous Immunoglobulin: An alternative therapy in steroid-dependent

63 Dr. Elizabeth Ann Esterl, RN October 10, 2017

allergic diseases. Clin Exp Immunol, 10461-66, 1996.

1998 Landwehr LP, Jeppson JD, Katlan MG, Esterl B, McCormick D, Hamilos DL, and Gelfand EW. Benefits of high dose intravenous immunoglobulin in patients with severe steroid-dependent asthma. Chest 114:1349-1356, 1998

2001 Abzug, MA, Esterl B. Establishment of a Clinical Trials Office at a Children’s Hospital. Pediatrics 2001.

2005 Kristine M. Bisgard, Philip Rhodes, Beverly L. Connelly, Daoling Bi, Christine Hahn, Sarah Patrick, Mary P. Glodé, Kristen R. Ehresmann and the Pertussis Investigation Team. Pertussis Vaccine Effectiveness Among Children 6 to 59 Months of Age in the United States, 1998–2001. Pediatrics 2005.

2005 Utterson, E. C., Shepherd, R. W., Sokol, R. J., Bucuvalas, J., Magee, J. C., McDiarmid, S. V., & Anand, R. (2005). Biliary atresia: clinical profiles, risk factors, and outcomes of 755 patients listed for liver transplantation. The Journal of pediatrics, 147(2), 180-185.

2006 Shneider, B. L., Brown, M. B., Haber, B., Whitington, P. F., Schwarz, K., Squires, R., ... & Sokol, R. J. (2006). A multicenter study of the outcome of biliary atresia in the United States, 1997 to 2000. The Journal of pediatrics, 148(4), 467-474.

2007 DeRusso, P. A., Ye, W., Shepherd, R., Haber, B. A., Shneider, B. L., Whitington, P. F., ... & Sokol, R. J. (2007). Growth failure and outcomes in infants with biliary atresia: a report from the Biliary Atresia Research Consortium. Hepatology, 46(5), 1632-1638.

2011 Russo, P., Magee, J. C., Boitnott, J., Bove, K. E., Raghunathan, T., Finegold, M., ... & Sokol, R. J. (2011). Design and validation of the biliary atresia research consortium histologic assessment system for cholestasis in infancy. Clinical Gastroenterology and Hepatology, 9(4), 357-362.

2015 Esterl, E. (2015). Reducing Variability Among Multiple Operators Using a Single Technique and Device for Skin Prick Testing in Children. Regis University Library.

2015 Mark J. Abzug, Marian G. Michaels, Ellen Wald, Richard F. Jacobs, José R. Romero,…….. and Elizabeth Esterl (2015). A Randomized, Double-Blind, Placebo-Controlled Trial of Pleconaril for the Treatment of Neonates With Enterovirus Sepsis. Journal of the Pediatric Infectious Diseases Society, Volume 5, Issue 1, 1 March 2016, Pages 53- 62, https://doi.org/10.1093/jpids/piv015

Invited Presentations and Participations

1990 Infusions Using IVIG. Film Sandoz Pharmaceuticals

1992 IVIG Infusions. Fitzsimmons Army Medical Center Physician and Pharmacist Lecture

1994 Parvovirus and IVIG. Rose Medical Center Nursing Conference

1994 Rapid Infusions with Sandoglobulin Multi-Centered Telecommunication Conference

64 Dr. Elizabeth Ann Esterl, RN October 10, 2017

1996 Rapid Infusions. Film Bayer Pharmaceuticals

1996 The Use of Intravenous Immunoglobulin: Practical Considerations in Disease State Management. Philadelphia, Pennsylvania

1996 Rapid Infusions of IVIG. Intravenous Nurses Society. Charlotte, North Carolina

1997 Children’s Miracle Network. Immunodeficiencies and IVIG. Denver, Colorado.

1997 Rapid Infusion of IVIG. Local Chapter of Intravenous Nurses Society. Denver, Colorado.

1998 IVIG and Asthma. Case Management Society Annual Meeting. Reno, Nevada.

1998 Infusion of IVIG, How’s and Why’s. Olsten Health Care. Englewood, Colorado.

1999 Infusion of IVIG. Intravenous Nurses Society. Charlotte, North Carolina

2001 National Institute of Health. Vaccination Protocols and Grants Review. Arlington, Virginia.

2002 National Institute of Health. Vaccination Protocols and Grants Review. Arlington, Virginia.

2014 35th Annual Keystone Pulmonary and Allery Conference. Keystone, Colorado

2014 Life Scripts. Human Enterovirus 68 interview for internet publication.

2014 NPR. Human Enterovirus 68 interview for internet publication.

2014 ABC Nightline. Human Enterovirus 68 interview for televised viewers.

2015 36th Annual Keystone Pulmonary and Allery Conference. Keystone, Colorado

2015 American Academy Allergy, Asthma and Immunology annual meeting. Skin Prick Test research protocol. Houston, Texas.

2015 Channel 9 News- Ask an Expert.

2016 37th Annual Keystone Pulmonary and Allery Conference. Keystone, Colorado

2016 Good Morning Vietnam- A global perspective of nursing education. Nursing Grand Rounds. National Jewish Health. Denver, Colorado.

2016 Colorado FARE Walk Chair. Food Allergy, Education and Research. Denver, Colorado

2017 Colorado FARE Community Engagement Leader. Colorado

2017 38th Annual Keystone Pulmonary and Allery Conference. Keystone, Colorado

65 Dr. Elizabeth Ann Esterl, RN October 10, 2017

2017 Colorado FARE Walk Team Leader, Board Member. Food Allergy, Education and Research. Denver, Colorado

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