2020 Aetna Florida Five Tier Open Small Group ACA Plan
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Incremental Costs of Introducing Jet Injection Technology for Delivery of Routine Childhood Vaccinations: Comparative Analysis from Brazil, India, and South Africa
Vaccine 29 (2011) 969–975 Contents lists available at ScienceDirect Vaccine journal homepage: www.elsevier.com/locate/vaccine Incremental costs of introducing jet injection technology for delivery of routine childhood vaccinations: Comparative analysis from Brazil, India, and South Africa Ulla K. Griffiths a,∗, Andreia C. Santos a, Neeti Nundy b, Erica Jacoby b, Dipika Matthias b a London School of Hygiene and Tropical Medicine, Tavistock Place, London WC1H 9SH, UK b PATH, 2201 Westlake Avenue, Suite 200, Seattle, WA 98121, USA article info abstract Article history: Background: Disposable-syringe jet injectors (DSJIs) have the potential to deliver vaccines safely and Received 14 May 2010 affordably to millions of children around the world. We estimated the incremental costs of transitioning Received in revised form 9 November 2010 from needles and syringes to delivering childhood vaccines with DSJIs in Brazil, India, and South Africa. Accepted 15 November 2010 Methods: Two scenarios were assessed: (1) DSJI delivery of all vaccines at current dose and depth; (2) a Available online 27 November 2010 change to intradermal (ID) delivery with DSJIs for hepatitis B and yellow fever vaccines, while the other vaccines are delivered by DSJIs at current dose and depth. The main advantage of ID delivery is that only Keywords: a small fraction of the standard dose may be needed to obtain an immune response similar to that of Vaccine Jet injector subcutaneous or intramuscular injection. Cost categories included were vaccines, injection equipment, Costs waste management, and vaccine transport. Some delivery cost items, such as training and personnel Brazil were excluded as were treatment cost savings caused by a reduction in diseases transmitted due to India unsafe injections. -
(12) Patent Application Publication (10) Pub. No.: US 2010/0221245 A1 Kunin (43) Pub
US 2010O221245A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2010/0221245 A1 Kunin (43) Pub. Date: Sep. 2, 2010 (54) TOPICAL SKIN CARE COMPOSITION Publication Classification (51) Int. Cl. (76) Inventor: Audrey Kunin, Mission Hills, KS A 6LX 39/395 (2006.01) (US) A6II 3L/235 (2006.01) A638/16 (2006.01) Correspondence Address: (52) U.S. Cl. ......................... 424/133.1: 514/533: 514/12 HUSCH BLACKWELL SANDERS LLP (57) ABSTRACT 4801 Main Street, Suite 1000 - KANSAS CITY, MO 64112 (US) The present invention is directed to a topical skin care com position. The composition has the unique ability to treat acne without drying out the user's skin. In particular, the compo (21) Appl. No.: 12/395,251 sition includes a base, an antibacterial agent, at least one anti-inflammatory agent, and at least one antioxidant. The (22) Filed: Feb. 27, 2009 antibacterial agent may be benzoyl peroxide. US 2010/0221 245 A1 Sep. 2, 2010 TOPCAL SKIN CARE COMPOSITION stay of acne treatment since the 1950s. Skin irritation is the most common side effect of benzoyl peroxide and other anti BACKGROUND OF THE INVENTION biotic usage. Some treatments can be severe and can leave the 0001. The present invention generally relates to composi user's skin excessively dry. Excessive use of some acne prod tions and methods for producing topical skin care. Acne Vul ucts may cause redness, dryness of the face, and can actually garis, or acne, is a common skin disease that is prevalent in lead to more acne. Therefore, it would be beneficial to provide teenagers and young adults. -
Pharmacy and Poisons (Third and Fourth Schedule Amendment) Order 2017
Q UO N T FA R U T A F E BERMUDA PHARMACY AND POISONS (THIRD AND FOURTH SCHEDULE AMENDMENT) ORDER 2017 BR 111 / 2017 The Minister responsible for health, in exercise of the power conferred by section 48A(1) of the Pharmacy and Poisons Act 1979, makes the following Order: Citation 1 This Order may be cited as the Pharmacy and Poisons (Third and Fourth Schedule Amendment) Order 2017. Repeals and replaces the Third and Fourth Schedule of the Pharmacy and Poisons Act 1979 2 The Third and Fourth Schedules to the Pharmacy and Poisons Act 1979 are repealed and replaced with— “THIRD SCHEDULE (Sections 25(6); 27(1))) DRUGS OBTAINABLE ONLY ON PRESCRIPTION EXCEPT WHERE SPECIFIED IN THE FOURTH SCHEDULE (PART I AND PART II) Note: The following annotations used in this Schedule have the following meanings: md (maximum dose) i.e. the maximum quantity of the substance contained in the amount of a medicinal product which is recommended to be taken or administered at any one time. 1 PHARMACY AND POISONS (THIRD AND FOURTH SCHEDULE AMENDMENT) ORDER 2017 mdd (maximum daily dose) i.e. the maximum quantity of the substance that is contained in the amount of a medicinal product which is recommended to be taken or administered in any period of 24 hours. mg milligram ms (maximum strength) i.e. either or, if so specified, both of the following: (a) the maximum quantity of the substance by weight or volume that is contained in the dosage unit of a medicinal product; or (b) the maximum percentage of the substance contained in a medicinal product calculated in terms of w/w, w/v, v/w, or v/v, as appropriate. -
For Nexplanon® Insertion and Removal G
Wilson et al. Contraception and Reproductive Medicine (2020) 5:1 Contraception and https://doi.org/10.1186/s40834-020-00104-x Reproductive Medicine RESEARCH Open Access Comparison of traditional anesthesia method and jet injector anesthesia method (MadaJet XL®) for Nexplanon® insertion and removal G. Anthony Wilson* , Julie W. Jeter, William S. Dabbs, Amy Barger Stevens, Robert E. Heidel and Shaunta’ M. Chamberlin Abstract Background: This study compared a needle-free anesthesia method with traditional local anesthesia for insertion and removal of Nexplanon® long-acting removable contraceptive device. In our clinic, patients often avoid this highly effective form of contraception due to fear of needles. We sought to determine if patients perceived a difference in pain with the injection, anxiety level or pain with the procedure when local anesthesia was given with a needle v/s a needle-free jet injector device. Methods: Patients were randomly assigned to one of two groups: jet injector or needle lidocaine delivery. Outcomes were ease of use, patient anxiety level, painfulness, and efficacy of anesthesia method. Results: Patient pain perception with administration of jet injector lidocaine was statistically lower than traditional needle with no difference in anxiety or ease of use, or efficacy of the anesthesia. Conclusion: The jet injector device is a reasonable alternative to needle injection delivery of anesthesia prior to insertion/removal of Nexplanon® device. Further studies may determine whether this needle-free alternative for administration of local anesthetic would result in more women choosing Nexplanon® as a contraceptive method. Keywords: Local anesthetic, Nexplanon®, Patient anxiety Background injection of lidocaine differed between the methods of As with many procedures [1, 2], patients often cite a fear delivery, and whether the presence or absence of needles of needles as a major reason to decline Nexplanon® in the anesthesia method affected patient anxiety level. -
“Rapper's Delight”
1 “Rapper’s Delight” From Genre-less to New Genre I was approached in ’77. A gentleman walked up to me and said, “We can put what you’re doing on a record.” I would have to admit that I was blind. I didn’t think that somebody else would want to hear a record re-recorded onto another record with talking on it. I didn’t think it would reach the masses like that. I didn’t see it. I knew of all the crews that had any sort of juice and power, or that was drawing crowds. So here it is two years later and I hear, “To the hip-hop, to the bang to the boogie,” and it’s not Bam, Herc, Breakout, AJ. Who is this?1 DJ Grandmaster Flash I did not think it was conceivable that there would be such thing as a hip-hop record. I could not see it. I’m like, record? Fuck, how you gon’ put hip-hop onto a record? ’Cause it was a whole gig, you know? How you gon’ put three hours on a record? Bam! They made “Rapper’s Delight.” And the ironic twist is not how long that record was, but how short it was. I’m thinking, “Man, they cut that shit down to fifteen minutes?” It was a miracle.2 MC Chuck D [“Rapper’s Delight”] is a disco record with rapping on it. So we could do that. We were trying to make a buck.3 Richard Taninbaum (percussion) As early as May of 1979, Billboard magazine noted the growing popularity of “rapping DJs” performing live for clubgoers at New York City’s black discos.4 But it was not until September of the same year that the trend gar- nered widespread attention, with the release of the Sugarhill Gang’s “Rapper’s Delight,” a fifteen-minute track powered by humorous party rhymes and a relentlessly funky bass line that took the country by storm and introduced a national audience to rap. -
Title 16. Crimes and Offenses Chapter 13. Controlled Substances Article 1
TITLE 16. CRIMES AND OFFENSES CHAPTER 13. CONTROLLED SUBSTANCES ARTICLE 1. GENERAL PROVISIONS § 16-13-1. Drug related objects (a) As used in this Code section, the term: (1) "Controlled substance" shall have the same meaning as defined in Article 2 of this chapter, relating to controlled substances. For the purposes of this Code section, the term "controlled substance" shall include marijuana as defined by paragraph (16) of Code Section 16-13-21. (2) "Dangerous drug" shall have the same meaning as defined in Article 3 of this chapter, relating to dangerous drugs. (3) "Drug related object" means any machine, instrument, tool, equipment, contrivance, or device which an average person would reasonably conclude is intended to be used for one or more of the following purposes: (A) To introduce into the human body any dangerous drug or controlled substance under circumstances in violation of the laws of this state; (B) To enhance the effect on the human body of any dangerous drug or controlled substance under circumstances in violation of the laws of this state; (C) To conceal any quantity of any dangerous drug or controlled substance under circumstances in violation of the laws of this state; or (D) To test the strength, effectiveness, or purity of any dangerous drug or controlled substance under circumstances in violation of the laws of this state. (4) "Knowingly" means having general knowledge that a machine, instrument, tool, item of equipment, contrivance, or device is a drug related object or having reasonable grounds to believe that any such object is or may, to an average person, appear to be a drug related object. -
Technical Considerations for Pen, Jet, and Related Injectors Intended for Use with Drugs and Biological Products
Guidance for Industry and FDA Staff: Technical Considerations for Pen, Jet, and Related Injectors Intended for Use with Drugs and Biological Products Additional copies are available from: Office of Combination Products Office of Special Medical Programs Office of the Commissioner Food and Drug Administration 10903 New Hampshire Avenue, WO-32 Hub 5129 Silver Spring, MD 20993 (Tel) 301-796-8930 (Fax) 301-796-8619 http://www.fda.gov/CombinationProducts/default.htm This document finalizes the draft guidance issued in April 2009. For questions regarding this document, contact the Office of Combination Products at [email protected] or Patricia Y. Love, MD at 301-796-8933 or [email protected] U.S. Department of Health and Human Services Food and Drug Administration Center for Devices and Radiological Health, Center for Drug Evaluation Research, Center for Biologics Evaluation and Research, and Office of Combination Products in the Office of the Commissioner June 2013 Contains Nonbinding Recommendations Table of Contents INTRODUCTION.....................................................................................................................3 BACKGROUND .......................................................................................................................4 SECTION I: SCIENTIFIC AND TECHNICAL CONSIDERATIONS.............................5 A. INJECTOR DESCRIPTION .............................................................................................5 B. DESIGN FEATURES.........................................................................................................9 -
Growth Hormone Treatment Without a Needle Using the Preci-Jet 50
Archives of Disease in Childhood 1997;76:65–67 65 Growth hormone treatment without a needle Arch Dis Child: first published as 10.1136/adc.76.1.65 on 1 January 1997. Downloaded from using the Preci-Jet 50 transjector P Bareille, M MacSwiney, A Albanese, C De Vile, R Stanhope Abstract Patients and methods A new delivery system (Preci-Jet 50) Twenty eight patients (11 girls, 17 boys) were which administers growth hormone randomly selected from the endocrine clinic at through the skin using high pressure and Great Ormond Street Hospital for Children. without a needle was evaluated. This All patients were receiving growth hormone device was inconvenient and painful com- treatment, 19 through an autoinjector and nine pared with a pen injection system. The with needles and syringes. None was using a conclusion is that the Preci-Jet is not the pen injector system at that time but nine had used one previously. The exclusion criteria panacea for solving the problem of com- were bleeding disorders and diseases of colla- pliance with subcutaneous growth hor- gen synthesis. Mean age was 10.1 (range mone injections. 5.7–16.7) years. The growth hormone dose ( 1997;76:65–67) Arch Dis Child range was from 15 to 30 IU/m2 body surface area/week. The subjects were randomly subdi- Keywords: growth hormone treatment; transcutaneous high pressure administration (jet); needle phobia. vided into two groups, A and B. Sex distribu- tion was similar in both groups but mean age diVered, with values of 8.7 and 11.2 years in groups A and B respectively. -
Dosage Form Description CODE
Dosage Form Description CODE DOSAGE_FORM DOSAGE_FORM DESCRIPTION AERO Aerosol AEPB Aerosol Powder, Breath Activated AERB Aerosol, Breath Activated AERP Aerosol, Powder AERS Aerosol, Solution AUIJ Auto-injector AJKT Auto-injector Kit BAR Bar BEAD Beads CAPS Capsule CAPA Capsule Abuse- Deterrent CPCW Capsule Chewable CPDR Capsule Delayed Release CPEP Capsule Delayed Release Particles CSDR Capsule Delayed Release Sprinkle CDPK Capsule Delayed Release Thereapy Pack C12A Capsule ER 12 Hour Abuse-Deterrent CS12 Capsule ER 12 Hour Sprinkle C2PK Capsule ER 12 Hour Therapy Pack C24A Capsule ER 24 Hour Abuse-Deterrent CS24 Capsule ER 24 Hour Sprinkle C4PK Capsule ER 24 Hour Therapy Pack CP12 Capsule Extended Release 12 Hour CP24 Capsule Extended Release 24 Hour CPEA Capsule Extended Release Abuse-Deterrent CSER Capsule Extended Release Sprinkle CEPK Capsule Extended Release Therapy Pack CPCR Capsule Extended Release* CPSP Capsule Sprinkle CPPK Capsule Therapy Pack CART Cartridge CTKT Cartridge Kit CONC Concentrate CREA Cream CRYS Crystals DEVI Device TEST Diagnostic Test DPRH Diaphragm DISK Disk ELIX Elixir EMUL Emulsion ENEM Enema EXHA Exhaler EXHL Exhaler Liquid Dosage Form Description CODE DOSAGE_FORM DOSAGE_FORM DESCRIPTION EXHP Exhaler Powder EXHS Exhaler Solution EXHU Exhaler Suspension FILM Film FLAK Flakes EXTR Fluid Extract FOAM Foam GAS Gas GEL Gel SOLG Gel Forming Solution GRAN Granules GREF Granules Effervescent GUM Gum IMPL Implant INHA Inhaler INJ Injectable INST Insert IUD Intrauterine Device JTAJ Jet-injector (Needleless) JTKT Jet-injector -
Cold and Flu Season
The DrugSmith is The Monthly Newsletter of The Smith Drug Company A Division of J M Smith Corporation Spartanburg, SC • Paragould, AR • Valdosta, GA Cold and Flu Season National Flu Vaccination Week World AIDS Month Introducing: Inject-Safe™ Barrier Bandage The first and only bandage designed specifically for injections. • Improved Safety Relieving Symptoms of the Common Cold 4 • Lower Cost National Influenza Vaccination Week 2016 6 • More Convenient • Less Pain What's New With The Flu? 7 Why Get A Flu Shot? 9 HealthWise Connect: Coming Soon! 11 World AIDS Day 12 Colon Rectal Cancer: Basic Facts 16 Healthwise™ Clinical Solutions Healthwise™ Circular Program DollarWise™ Program Good Sense® Controlled Label Program Greeting Cards Program Continuing Education Gift and Trade Show ™ Benefits of the Inject-Safe™ Barrier Bandage Rx QuickShip Third Party Station Inject-Safe™ Barrier Bandages self-seal to help contain Pharmacy First bleeding following an injection. DrugSmith™ Monthly Newsletter Consistent with “Universal Precautions” established by Smith Weekly e-Blast OSHA. Diabeticare Program Hamacher Retail Zone Pricing Protects the healthcare provider from coming into contact with potential blood borne pathogens. Home Health Care Catalog HealthWise Signage Program Allows healthcare provider to use both hands to dispose of Smith Gift Box Gift Category the needle. Vials and Vitamin Program Meets OSHA Blood borne Pathogen Standard's definition Direct Mail Advertising of "Engineering Control," for use to reduce employee Well Staffed Customer Service -
2010 National Ambulatory Medical Care Survey Public Use Data File
2010 NAMCS MICRO-DATA FILE DOCUMENTATION PAGE 1 ABSTRACT This material provides documentation for users of the 2010 National Ambulatory Medical Care Survey (NAMCS) public use micro-data file. NAMCS is a national probability sample survey of visits to office-based physicians conducted by the National Center for Health Statistics, Centers for Disease Control and Prevention. It is a component of the National Health Care Surveys which measure health care utilization across a variety of health care providers. Section I, "Description of the National Ambulatory Medical Care Survey," includes information on the scope of the survey, the sample, field activities, data collection procedures, medical coding procedures, population estimates, and sampling errors. Section II provides technical information, including a detailed description of the contents of each data record by location, and a list of physician specialties represented in the survey. Section III contains marginal data and estimates for selected items on the data record. The appendixes contain sampling errors, instructions and definitions for completing the Patient Record form, and lists of codes used in the survey. PAGE 2 2010 NAMCS MICRO-DATA FILE DOCUMENTATION SUMMARY OF CHANGES FOR 2010 The 2010 NAMCS public use micro-data file is, for the most part, similar to the 2009 file, but there are some important changes. These are described in more detail below and reflect changes to the survey instruments, the Patient Record form and the Physician Induction Interview form. There are also new injury-related items on the public use file, but these are simply recoded data from existing items on the Patient Record form and are described in a separate section below. -
Megan Thee Stallion, Fever
REVIEWS Megan Thee Stallion Fever 8.0 1501 CERTIFIED / 300 ENTERTAINMENT • 2019 BY: TAYLOR CRUMPTON / MAY 23 2019 RAP Megan Thee Stallion’s debut is steeped in sex, pimpin, and power; it sounds like a once and future Houston rap classic. hen MeganMeganMegan TheeTheeThee StallionStallionStallion’s “Big Ole Freak” landed on Billboard’s Hot 100 in April, it was a testament to years of viral W freestyles and her devoted “hotties,” whose faithful support on social media helped the song rise to mainstream recognition. The 24- year-old has been prolific—her evolution is displayed through the invention of various rap personas, such as Tina Snow, Megan Thee Stallion, and Hot Girl Meg, the turn-up queen with serious ambition on her mind. “We have so many legends and so many greats,” she recently said of her hometown of Houston, Texas. “But I don’t feel like we ever really had a female rapper from Houston or Texas shut that shit down.” With her debut project Fever, she hopes to succeedMegan in doing Thee just Stallion that. At its core is the intersection of two beautiful rap legacies: the women rap tradition started by MCMCMC LyteLyteLyte and QueenQueenQueen LatifahLatifahLatifah, and Southern rap dynasty ushered in by Houston’s GetoGetoGeto BoysBoysBoys and UndergroundUndergroundUnderground KingsKingsKings. From the first song, Megan weaponizes misogynymisogynymisogyny through the execution of bars worthy of XXL Freshman Class President. South Park’s influence, home to fellow Houston legends ScarfaceScarfaceScarface and Lil’Lil’Lil’ KekeKekeKeke, is felt throughout “Hood Rat Shit,” which transitions into an ass-and clit-eating tutorial for her male tricks on “Pimpin,” where the spirit of Houston’s pimp tradition is embedded within every word.