Ccdc57 (NM 027745) Mouse Tagged ORF Clone – MG211452

OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for MG211452

Ccdc57 (NM_027745) Mouse Tagged ORF Clone Product data:

Product Type: Expression Plasmids Product Name: Ccdc57 (NM_027745) Mouse Tagged ORF Clone Tag: TurboGFP Symbol: Ccdc57 Synonyms: 4933434G05Rik Vector: pCMV6-AC-GFP (PS100010) E. coli Selection: Ampicillin (100 ug/mL) Cell Selection: Neomycin ORF Nucleotide >MG211452 representing NM_027745 Sequence: Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC

ATGCTGCCGCTATGTTCAGAGCGGGAACTGAATGAGCTTTTGGCTCGAAAGGAGGAGGAATGGCGAGTCC TCCAGGCCCACCGTGCGCAGCTGCAGGAGGCAGCTCTACAGGCTGCTCAGAACCGCCTGGAGGAGACACA GGGGAAGCTGCAACGCCTACAGGAGGACTTTGTTTACAACCTTCAGGTGCTGGAAGAGCGGGACCGGGAG CTGGAGCGCTATGATGTTGAGTTCACCCAGGCCCGCCAGCGGGAGGAGGCCCAACAAGCAGAGGCCAGTG AGCTCAAGATAGAGGTGGCCAAGCTGAAACAAGACCTCACCAGGGAGGCCAGGCGAGTGGGGGAGCTGCA GCATCAGCATCAGCTAATGCTGCAGGAGCATCGCTTGGAGTTGGAGCGCGTCCACAGTGACAAGAACAGC GAACTGGCCCACCAGCGGGAACAGAATGAGCGCCTGGAGTGGGAACTGGAGCGAAAACTGAAGGAACTCG ATGGTGAACTTGCTCTGCAGAGACAGGAGCTGCTGCTGGAGTTTGAATCTAAAATGCAGAGAAGAGAGCA TGAGTTCCAGCTGAGGGCTGACGACATGAGCAACGTAGTCCTGACACATGAGCTCAAGATAAAACTACTA AACAAAGAGCTGCAAGCTCTGAGAGACGCTGGAGCACGGGCAGCAGAGAGTCTGCAGAAGGCAGAAGCAG AACACGTGGAATTAGAGAGGAAGCTGCAGGAGCGTGCCCGGGAACTCCAGGATCTGGAGGCCGTGAAGGA CGCTCGGATAAAGGGCTTGGAGAAGAAGCTTTACTCGGCACAGCTGGCCAAGAAGAAAGCTGAGGAGACT TTCAGGAGGAAACATGAAGAGCTTGACCGTCAAGCCAGGGAGAAAGACACAGTGCTGGCGGCAGTGAAGC GCGCCCATGCAGAGGAGCTGCAGACGCTGGACGCCAAGGTGCTGGAGCTTCAGTTCCTCTGTGAAACCCT GGAGGGACAACTGCGCAGGGCTGAGTGCACAAGAGCAGAGGACGCCAAGGAGAAGAACGCCCTTACTGAC AAATTTCGTGAAGATGCGGCAGCTCTGAAAGCTGCCTGGGACGCCCAGATCACGCAGATGTCCAAGGAGA CTGTCTCCAAAGACTTTCAGATTCACACGCTGCAGGAAGAAGAGATGAAGCTCAAGGCACAGGTGGCCAG ATTCCAACAGGACATAGACAGGTACAAGCAGCAGCTGTCCCTGGCAGTGGAGAGGGGACAGAGCCTGGAG CGTGAACAGGTACAGCTAGGCCTTGACTGGCAGCGTCGCTGCGATGATATTGAACGAGACCAGATCCAGA AATCGGAGACTTTGATCGAAGGGCTGACCAAGGCCAGGGATCAGGTCGCTGCTAAACTCCAGGAGACAGA GAAGGCACTGCGTCAGCAGGAGACTCTGCTGAAGGCTGTGTCACTGGAGCGAGACCAAGCTATGGAAACC CTACGTACACATGGGCTCCTTCCTGGACAGGAGGCACAGGTACCTCCTCAGCAGCATGAAGGAGAAATAA

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 4 Ccdc57 (NM_027745) Mouse Tagged ORF Clone – MG211452

GGGCAGATTCTCCATCTACTGAGATCCAGAGGCTACAGGAACAGAATGCAGGTCTGCGGAACGCTGTTTC ACAGATGAGGAGAGAGATGGAGATGCTGAGCGGTCATCTCCCCCCTGCCCAGCCAGAAGAGTGTTCAAAT GCAGACCCTGATCCCAAGGCTGGAGGAGACTCCACCCCTCCAGATTATGTTCTGACCCTTGAAGCAGAAA TGCAAAATCTAAAGCATAAACTTAAGGCATTGGAGGAACAACTACAAAGCACAGAAGAGCCAGTGAAGAC GTCCGTGGCCACTGCTGATCCACACCATGGTGTCCACAGCTCTGCAGCAGCAGCTGACGCAGCTCTGGCA GACCAGACATCCACTGCATTAGCACTCAGAAAACTTGGAGACAGAGTGCACCTCTTGAACTTGCTGGTGA CACAGCTCAAAAGGAAGCTGCGGCAGAAGCCCCGGGAGCTGGTCCCTGTCCAACACGAGGTCCCCAGTGA GGTGGACCAGGTGCACCTGGAGGTTTTGGAGCTGCAGAAGCAGGTGGCTGAGTTAAGGAAGCATCTCAAG GTGACACCCCAGGGAGAGCCTTCATCCAGGGAGCAGTTACAGAGACAGGGTGTGGCAGACCGGTACCCCA TGGGCATGGAAGACCAGACGGAGTCCCCTACTTTCCCCCAGGAAGGGGCACAGCCTCCACAGACCATATA TGTGACCCATCTGCAAAGGAAATTAAAGGATGCAGCTAGGAAAATACTCAGCCTCCGCCTAGAGAGGGAA CAGCTCCTAGAAATGGGAAATAGACTCCGAGCTGAGCAAGGCCACGCAAAAGGGAAACCAACTCCTTGCC CAGGTCCTCCCACCTCTGAACCCCAGGACCCCCAGGAGGTGCCTGAGAGATCTTTGGACCGTGGCCCACC TTTGGGACAATTGCAGCCCTACTCAACAACTCAGGACCCCAGGCACACCAAGAGAAGATGTGCTTCTGAG TATGCAGGGAAGAGTCAACCCCACTCAGCACAAGTGGGCAGCAAAACCAACACCCCACGAGGCCACAAGG CAGAAATGGCGTCAAGGCCTGCTCAGCTCTCACAGAAGCAGCACAGAATCCCCACAGAGACTTGGAAGCC AGTTTATCAGAAAGAAAACAGGACCCCAAAGCTACCACAGGCTCATGAAGTCCCTGAAGAAAGTGACCAC CGTACCCACAGATCGTCTTCATTGGCCAGCAGTTCCCTCCAAGACATCTGGAGGCTGCTAGAGCTGGGAT CCAGCCCTTCGGGCGTCCCCTCACAGGATAACTCTGTTGCAGAGTGTCCAGCACCTTCAAGACCCAGCTG TTTCCAAAAGGTCAACCGGAGCCCTGTCCCCATACAAAAGGCCTTTGCTGTCAAAGGGCTAAAGATGGAA GCTCAGCCAAAAGCCACACCCCCCAGACCCAGCAAGTCTCACCCAGCTAAACCTACAAACTGCCAGCAGC AGCGGCCCTCTAGGATCCGCAACTACAACCTCAAGGAC

ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA Protein Sequence: >MG211452 representing NM_027745 Red=Cloning site Green=Tags(s)

MLPLCSERELNELLARKEEEWRVLQAHRAQLQEAALQAAQNRLEETQGKLQRLQEDFVYNLQVLEERDRE LERYDVEFTQARQREEAQQAEASELKIEVAKLKQDLTREARRVGELQHQHQLMLQEHRLELERVHSDKNS ELAHQREQNERLEWELERKLKELDGELALQRQELLLEFESKMQRREHEFQLRADDMSNVVLTHELKIKLL NKELQALRDAGARAAESLQKAEAEHVELERKLQERARELQDLEAVKDARIKGLEKKLYSAQLAKKKAEET FRRKHEELDRQAREKDTVLAAVKRAHAEELQTLDAKVLELQFLCETLEGQLRRAECTRAEDAKEKNALTD KFREDAAALKAAWDAQITQMSKETVSKDFQIHTLQEEEMKLKAQVARFQQDIDRYKQQLSLAVERGQSLE REQVQLGLDWQRRCDDIERDQIQKSETLIEGLTKARDQVAAKLQETEKALRQQETLLKAVSLERDQAMET LRTHGLLPGQEAQVPPQQHEGEIRADSPSTEIQRLQEQNAGLRNAVSQMRREMEMLSGHLPPAQPEECSN ADPDPKAGGDSTPPDYVLTLEAEMQNLKHKLKALEEQLQSTEEPVKTSVATADPHHGVHSSAAAADAALA DQTSTALALRKLGDRVHLLNLLVTQLKRKLRQKPRELVPVQHEVPSEVDQVHLEVLELQKQVAELRKHLK VTPQGEPSSREQLQRQGVADRYPMGMEDQTESPTFPQEGAQPPQTIYVTHLQRKLKDAARKILSLRLERE QLLEMGNRLRAEQGHAKGKPTPCPGPPTSEPQDPQEVPERSLDRGPPLGQLQPYSTTQDPRHTKRRCASE YAGKSQPHSAQVGSKTNTPRGHKAEMASRPAQLSQKQHRIPTETWKPVYQKENRTPKLPQAHEVPEESDH RTHRSSSLASSSLQDIWRLLELGSSPSGVPSQDNSVAECPAPSRPSCFQKVNRSPVPIQKAFAVKGLKME AQPKATPPRPSKSHPAKPTNCQQQRPSRIRNYNLKD

TRTRPLE - GFP Tag - V Restriction Sites: SgfI-MluI

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 4 Ccdc57 (NM_027745) Mouse Tagged ORF Clone – MG211452

Cloning Scheme:

Plasmid Map:

ACCN: NM_027745 ORF Size: 3048 bp

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 3 / 4 Ccdc57 (NM_027745) Mouse Tagged ORF Clone – MG211452

OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. RefSeq: NM_027745.1, NP_082021.1 RefSeq Size: 3437 bp RefSeq ORF: 3051 bp Locus ID: 71276 UniProt ID: Q6PHN1 Gene Summary: Pleiotropic regulator of centriole duplication, mitosis, and ciliogenesis (PubMed:32402286). Critical interface between centrosome and microtubule-mediated cellular processes. Centriole duplication protein required for recruitment of CEP63, CEP152, and PLK4 to the centrosome. Independent of its centrosomal targeting, localizes to and interacts with microtubules and regulates microtubule nucleation, stability, and mitotic progression (By similarity). [UniProtKB/Swiss-Prot Function]