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Table 1. Search strategy

#1 MeSH descriptor: [Apitherapy] explode all trees

#2 MeSH descriptor: [] explode all trees

#3 MeSH descriptor: [Color Therapy] explode all trees

#4 MeSH descriptor: [] explode all trees

#5 MeSH descriptor: [Flower Essences] explode all trees

#6 (Apitherapy) OR (Apitoxins) OR (Apipuncture) OR ( Venom Therapy) OR (Bee Venom) OR () OR () OR (Aromatherapy) OR (Bioenergetic) OR (Bioenergetic Therapy) OR (Bioenergetic Analysis) OR (Bioenergetic Psychotherapy) OR (Family Constellation) OR (Family Constellation Therapy) OR (Therapy, Color) OR (Chromatotherapy) OR () OR (Colour Light Therapy) OR (Geotherapy) OR () OR (Hypnosis) OR (Healing Touch) OR (Hand Imposition) OR ( Channel) OR (Therapeutic Touch) OR (Energy Heal) OR (Laying-on-of-Hands) OR (Touch, Therapeutic) OR (Ozone) OR () OR (Flower Essences) OR (Essences, Flower) OR () OR (Flower Remedies, Bach) OR (Remedies, Bach Flower) OR (Bach Flowers) OR (Flowers, Bach) OR (Bach Flower Essences) OR (Essences, Bach Flower) OR (Flower Essences, Bach) OR (Flowering Top) OR (Top, Flowering) OR (Tops, Flowering) OR (Magnoliopsida) OR (Flowering Plants) OR (Flowering Plant) OR (Plant, Flowering) OR (Plants, Flowering) OR (Rosaceae) OR (Quince, Flowering) OR (Flowering Quince) OR (Flowering Quinces) OR (Quinces, Flowering) OR (Passiflora) OR (Passion Flower) OR (Flower, Passion) OR (Flowers, Passion) OR (Passion Flowers) OR (Platycodon) OR (Balloon Flower) OR (Balloon) OR (Flower, Balloon) OR (Flowers, Balloon) OR (Fraxinus) OR (Flowering Ash) OR (Ash, Flowering) OR (Ashs, Flowering) OR (Flowering Ashs) OR (Inflorescence) OR (Flower Head) OR (Flower Heads) OR (Head, Flower) OR (Heads, Flower) OR (Florigen) OR (Flowering Hormone) OR (Hormone, Flowering) OR (Integrative)

#7 #1 or #2 or #3 or #4 or #5 or #6

Filters: in Cochrane Reviews; in Title, Abstract, Keywords Table 2. Characteristics of the included systematic reviews.

Integrative practice Study title Number of Number of Publication Overall trials participants year GRADE included (last version) asessment

Apitherapy Honey as a topical 26 3011 2015 Very low to treatment for wounds high certainty

Apitherapy Honey for acute cough in 3 568 2014 Low to high children certainty

Apitherapy Venom immunotherapy 7 392 2012 Moderate to for preventing allergic high certainty reactions to stings

Apitherapy Honey and lozenges for None None 2009 Not assessed children with non‐ specific cough

Aromatherapy Aromatherapy for 16 1036 2018 Very low to treatment of moderate postoperative nausea and certainty vomiting Aromatherapy Aromatherapy for 7 428 2014 Not assessed dementia

Aromatherapy Massage with or without 19 1274 2016 Not assessed aromatherapy for symptom relief in people with

Aromatherapy Aromatherapy for pain 2 535 2011 Not assessed management in labour

Hypnotherapy for 4 147 2007 Not assessed treatment of irritable Hypnotherapy bowel syndrome

Hypnosis during 1 63 2012 Not assessed pregnancy, childbirth, Hypnotherapy and the postnatal period for preventing postnatal depression Hypnosis for induction of None None 2014 Not assessed labour Hypnotherapy

Hypnosis for pain 9 2954 2016 Very low to low management during certainty Hypnotherapy labour and childbirth

Hypnosis for 3 149 2007 Not assessed schizophrenia Hypnotherapy

Hypnotherapy for 11 1120 2010 Not assessed smoking cessation Hypnotherapy

Ozone therapy for 3 212 2015 Not assessed treating foot ulcers in Ozone therapy people with diabetes

Ozone therapy for the 3 137 2004 Not assessed treatment of dental caries Ozone therapy