1980–1989

1981 1982 1984 1985 1986 1988 1989 Daivd Hubel Bengt Samuelsson Niels Jerne Michael Brown Rita Levi–Montalcini Gertrude Elion Harold Varmus

1980 1980 1981 1982 1984 1985 1987 1988 Baruk Benacerraf George Snell Torsten Wiesel John Vane Georges Köhler Joseph Goldstein Susumu Tonegawa George Hitchings

1980980 198181 1982982 198383 198484 198686 1988988 198989 Jean Dausset Robert Sperry Sune Berfstöm Barbara McClintock César Milstein Stanley Cohen Sir James Black Michael Bishop

1980 12th Epilepsy International Symposium in Copenhagen – 295 delegates 1981 13th Epilepsy International Symposium in Kyoto – 894 delegates 1981 Epilepsy International disbanded and concept of merger between IBE and ILAE abandoned 1981 First regional ILAE symposium held in Yucatán – Epilepsia Pan–American 1981 Revision of the ILAE Classifi cation of Epileptic Seizures approved 1982 14th Epilepsy International Symposium in London – 587 delegates 1982 First investigations of SPECT scanning in epilepsy 1982 Frank Morrell and Walter Whisler report the fi rst clinical epilepsy cases treated by multiple subpial transection 1982 First large published series of neurological patients, some with epilepsy, investigated by MRI 1983 DDR join the ILAE 1983 15th Epilepsy International Symposium in Washington – 700 delegates 1984 MRS studies of epilepsy initiated

1985 Progabide licensed in France, but not elswhere 1985 16th Epilepsy International Symposium in Hamburg – 1200 delegates 1985 Colombia, Ecuador, Guatemala, Indonesia and Yugoslavia join the ILAE 1985 Publication of fi rst edition of Epilepsy Syndromes in infancy, childhood and adolescence 1986 Landmark studies of prognosis in epilepsy published in Epilepsia 1987 17th Epilepsy International Congress in Jerusalem – 1126 delegates and satellite symposia for the fi rst time 1987 Algeria and Australia join the ILAE 1988 Treatment gap in epilepsy fi rst calculated – in three countries 1989 Hungary, Morocco, Panama, Venezuela and Zaire join the ILAE, and Cuba, Sweden and Peru submit revised constitutions. The ILAE now consisted of 39 chapters 1989 Wave of new drugs begins, with the introduction of vigabatrin in Europe and Zonisamide in Japan 1989 18th International Epilepsy Congress – in New Delhi

1980 Commercial production of genetically engineered insulin 1985 BSE fi rst formally described 1981 AIDs fi rst described 1986 First heart, lung and liver transplant 1982 Prions fi rst described by Stanley Prusiner 1986 First monoclonal antibody drug 1983 H. pylori described as a cause of stomach ulcers by Robin Warren and Barry Marshall 1987 Prozac makes its debut 1984 HIV identifi ed 1988 Fluvoxetine approved by the FDA 1989 Gene causing cystic fi brosis discovered

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