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Cell Circuitry || Science Teaches English || The Chicken Genome Is Hot || Magnets in Medicine SEPTEMBER 2002 www.hhmi.org/bulletin Leading Doublea Life It’s a stretch, but doctors who work bench to bedside say they wouldn’t do it any other way. FEATURES 14 On Human Terms 24 The Evolutionary War A small—some say too small—group of Efforts to undermine evolution education have physician-scientists believes the best science evolved into a 21st-century marketing cam- requires patient contact. paign that relies on legal acumen, manipulation By Marlene Cimons of scientific literature and grassroots tactics. 20 Engineering the Cell By Trisha Gura Adam Arkin sees the cell as a mechanical system. He hopes to transform molecular 28 Call of the Wild biology into a kind of cellular engineering Could quirky, new animal models help scien- and in the process, learn how to move cells tists learn how to regenerate human limbs or from sickness to health. avert the debilitating effects of a stroke? By M. Mitchell Waldrop By Kathryn Brown 24 In front of a crowd of 1,500, Ohio’s Board of Education heard testimony on whether students should learn about intelligent design in science class. DEPARTMENTS 2 NOTA BENE 33 PERSPECTIVE ulletin Intelligent Design Is a Cop-Out 4 LETTERS September 2002 || Volume 15 Number 3 NEWS AND NOTES HHMI TRUSTEES PRESIDENT’S LETTER 5 JAMES A. BAKER, III, ESQ. 34 Senior Partner, Baker & Botts A Creative Influence In from the Fields ALEXANDER G. BEARN, M.D. Executive Officer, American Philosophical Society 35 Lost on the Tip of the Tongue Adjunct Professor, The Rockefeller University UP FRONT Professor Emeritus of Medicine, Cornell University Medical College 36 Biology by Numbers FRANK WILLIAM GAY 6 Follow the Songbird Former President and Chief Executive Officer, SUMMA Corporation JAMES H. -
Which Canadian Charities Had the Largest Assets in 2014?
www.canadiancharitylaw.ca Which Canadian charities had the largest assets in 2014? By Mark Blumberg (March 23, 2016) We recently reviewed the T3010 information for 2014. It covers about 84,370 of the 86,000 registered charities that have so far filed their return and that have been entered into the CRA’s database. Canadian registered charities are currently required to disclose on the T3010 their assets. The total assets of all the 84,370 registered charities were about $373,050,327,255.00. Below we have a table of Canadian charities and how much they spent as reported for the 2014 fiscal year. Thank you to Celeste Bonas, an intern at Blumbergs, for helping with this project. The Sean Blumberg Transparency Project is in memory of my youngest brother Sean Blumberg. Sean was a sweet, kind person, a great brother who helped me on a number of occasions with many tasks including the time consuming and arduous task of reviewing T3010 databases and making them into something useful. As part of the Sean Blumberg Transparency Project, Blumbergs has been releasing information on the Canadian charity sector to provide a better understanding of the size, scope, complexity and challenges of the sector. Please review my caveats at the end about the reliability and usage of T3010 information. 1 www.canadiancharitylaw.ca List of Canadian charities with the largest assets in 2014 Line 4200 Name of Canadian Registered Charity largest assets 1. ALBERTA HEALTH SERVICES $9,984,222,000.00 2. THE MASTERCARD FOUNDATION $9,579,790,532.00 3. THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO $7,681,040,000.00 4. -
2015 Annual Report
1 TABLE OF CONTENTS TABLE OF CONTENTS ............................................................................................................................. 2 HISTORY OF THE GAIRDNER FOUNDATION .................................................................................... 3 MISSION ...................................................................................................................................................... 3 NATIONAL AND STUDENT OUTREACH PROGRAMS ....................................................................... 4 MESSAGE FROM THE CHAIR ............................................................................................................... 5 MESSAGE FROM THE PRESIDENT/SCIENTIFIC DIRECTOR ......................................................... 6 2015 YEAR IN REVIEW ............................................................................................................................. 7 REPORT ON 2015 OBJECTIVES ............................................................................................................ 14 THE YEAR AHEAD: OBJECTIVES FOR 2016 ..................................................................................... 16 THE GAIRDNER FOUNDATION VALUES OUR 2015 SPONSORS ................................................... 18 GOVERNANCE ......................................................................................................................................... 20 MEDICAL REVIEW PANEL 2015 ......................................................................................................... -
EMBC Annual Report 2007
EMBO | EMBC annual report 2007 EUROPEAN MOLECULAR BIOLOGY ORGANIZATION | EUROPEAN MOLECULAR BIOLOGY CONFERENCE EMBO | EMBC table of contents introduction preface by Hermann Bujard, EMBO 4 preface by Tim Hunt and Christiane Nüsslein-Volhard, EMBO Council 6 preface by Marja Makarow and Isabella Beretta, EMBC 7 past & present timeline 10 brief history 11 EMBO | EMBC | EMBL aims 12 EMBO actions 2007 15 EMBC actions 2007 17 EMBO & EMBC programmes and activities fellowship programme 20 courses & workshops programme 21 young investigator programme 22 installation grants 23 science & society programme 24 electronic information programme 25 EMBO activities The EMBO Journal 28 EMBO reports 29 Molecular Systems Biology 30 journal subject categories 31 national science reviews 32 women in science 33 gold medal 34 award for communication in the life sciences 35 plenary lectures 36 communications 37 European Life Sciences Forum (ELSF) 38 ➔ 2 table of contents appendix EMBC delegates and advisers 42 EMBC scale of contributions 49 EMBO council members 2007 50 EMBO committee members & auditors 2007 51 EMBO council members 2008 52 EMBO committee members & auditors 2008 53 EMBO members elected in 2007 54 advisory editorial boards & senior editors 2007 64 long-term fellowship awards 2007 66 long-term fellowships: statistics 82 long-term fellowships 2007: geographical distribution 84 short-term fellowship awards 2007 86 short-term fellowships: statistics 104 short-term fellowships 2007: geographical distribution 106 young investigators 2007 108 installation -
Profile of Gary Ruvkun
PROFILE Profile of Gary Ruvkun wash in the faint glow of a fluo- Brush with Molecular Biology rescent lamp, a pair of serpentine The story of Ruvkun’s metamorphosis Anematode worms lie on a Petri from a keen undergraduate into a leading plate, their see-through bodies light in his field of study begins at Har- magnified 100-fold by one of several vard University, where he enrolled in microscopes arrayed in a darkened bay in a Ph.D. program in 1976 upon returning National Academy of Sciences member to the United States. Like many other Gary Ruvkun’s laboratory at Massachu- scientific institutions across the world in setts General Hospital. While one of the the mid-1970s, Harvard was astir with the worms wiggles its way around the plate, promise of recombinant DNA technol- the other shows no signs of life, ogy, and Ruvkun wasted no time em- its midsection ruptured and its innards bracing its tools. “My undergraduate strewn asunder. A filter slides into place, education had not prepared me at all for and the worms are bathed in a dull recombinant DNA, but I immersed my- green haze. The wiggling worm has a bea- self into its culture at Harvard, much of con of nerve cells in its head, the ganglia which was James Watson’s creation from lit up by a genetic trick that has rescued a decade earlier,” Ruvkun says. Propelled the worm from death; its neighbor wears Gary Ruvkun. by a desire to be a part of the culture of no such beacon. The worms were deprived basic molecular biology, all while per- of a tiny RNA molecule, called a micro- forming science with the potential to im- RNA, which helps shepherd them through not 5-year-old children. -
Professor Peter Goldreich Member of the Board of Adjudicators Chairman of the Selection Committee for the Prize in Astronomy
The Shaw Prize The Shaw Prize is an international award to honour individuals who are currently active in their respective fields and who have recently achieved distinguished and significant advances, who have made outstanding contributions in academic and scientific research or applications, or who in other domains have achieved excellence. The award is dedicated to furthering societal progress, enhancing quality of life, and enriching humanity’s spiritual civilization. Preference is to be given to individuals whose significant work was recently achieved and who are currently active in their respective fields. Founder's Biographical Note The Shaw Prize was established under the auspices of Mr Run Run Shaw. Mr Shaw, born in China in 1907, was a native of Ningbo County, Zhejiang Province. He joined his brother’s film company in China in the 1920s. During the 1950s he founded the film company Shaw Brothers (HK) Limited in Hong Kong. He was one of the founding members of Television Broadcasts Limited launched in Hong Kong in 1967. Mr Shaw also founded two charities, The Shaw Foundation Hong Kong and The Sir Run Run Shaw Charitable Trust, both dedicated to the promotion of education, scientific and technological research, medical and welfare services, and culture and the arts. ~ 1 ~ Message from the Chief Executive I warmly congratulate the six Shaw Laureates of 2014. Established in 2002 under the auspices of Mr Run Run Shaw, the Shaw Prize is a highly prestigious recognition of the role that scientists play in shaping the development of a modern world. Since the first award in 2004, 54 leading international scientists have been honoured for their ground-breaking discoveries which have expanded the frontiers of human knowledge and made significant contributions to humankind. -
Kazutoshi Mori and Peter Walter Receive the 2014 Albert Lasker Basic Medical Research Award
Kazutoshi Mori and Peter Walter receive the 2014 Albert Lasker Basic Medical Research Award Corinne L. Williams J Clin Invest. 2014;124(10):4138-4142. https://doi.org/10.1172/JCI78419. News Cells are continuously faced with life-and-death decisions based on their ability to handle stressful situations. One indicator of stress is the accumulation of unfolded proteins within the ER, which induces a transcriptional cascade aimed at increasing the folding capacity of the ER. If the burden is too great and homeostasis cannot be restored, the response shifts from damage control to the induction of apoptotic pathways. This unfolded protein response (UPR) is conserved among all eukaryotes, and dysfunction in this pathway underlies many human diseases, including diabetes and cancer. The 2014 Albert Lasker Basic Medical Research award honors Kazutoshi Mori of Kyoto University and Peter Walter of the UCSF (Figure 1) for their contributions toward unraveling the pathways involved in mediating the complex cellular response to ER stress. A simple question In the 1970s, the identification of a set of proteins that were induced in response to viral transformation set the stage for understanding heat shock-independent cellular stress responses. These particular proteins were constitutively present in cells and notably increased in response to glucose deprivation (1) or agents that block post-translational glycosylation, such as tunicamycin. Based on this apparent glucose-dependent regulation, they became known as glucose-regulated proteins (GRPs). One -
2008 Harvard / Paul F
The 2008 Harvard / Paul F. Glenn Symposium on Aging June 23, 2008 Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Welcome to the 3rd Annual Harvard/Paul F. Glenn Symposium on Aging. Each year, the Paul F. Glenn Laboratories host the Harvard Symposium on Aging with a mission to educate the wider research community about advancements in this fast-paced field and to stimulate collaborative research in this area. We have been fortunate to have many of the leaders in the aging field speak at these symposia. As a result, attendees come not only from the Harvard research community but from across the nation and from overseas for this one day event. We are glad you could join us here today. The reasons for accelerating research molecular biology of aging are clear. First and foremost, the number of aged individuals in developed countries is growing rapidly, which is going to place an unprecedented burden on the families and the economies of those nations. Because chronic illness in the elderly is a major medical cost, enormous savings would be achieved if mortality and morbidity could be compressed within a shorter duration of time at the end of life. A study by the RAND Corporation in 2006 concluded that advances in medicine arising from aging research would be 10-100 times more cost-effective than any other medical breakthrough. Advances in aging research have shown that it is possible to extend the healthy lifespan of laboratory animals through genetic and pharmacological means. Many leaders in the aging field predict that significant strides will be made in understanding how human health and lifespan are regulated, leading to novel medicines to forestall and treat diseases of aging such as diabetes, cancer, Alzheimer’s and heart disease. -
CAHS) 180 Elgin Street, Suite 1403, Ottawa, on Canada K2P 2K3
From Concept to Impact – 10 Years of Progress SCIENTIFIC ADVICE FOR A HEALTHY CANADA The Canadian Academy of Health Sciences (CAHS) 180 Elgin Street, Suite 1403, Ottawa, ON Canada K2P 2K3 Notice: This history of the Canadian Academy of ISBN 978-0-9877815-5-0 (paperback). Health Sciences was authored by John A Cairns ISBN 978-0-9877815-6-7 (pdf) (CAHS president 2013-15) and Paul W Armstrong (CAHS president 2004-07) on behalf of the 1. 2. 3. Entries to be received from Library and Academy and with the approval of the Board of Archives Canada. CAHS. The information contained herein is based Codes to be received from Library and Archives upon the personal perspectives of the authors Canada. gained since the earliest planning of the CAHS I. Canadian Academy of Health Sciences, issuing and augmented by perusal of the electronic body archives of the CAHS and the Council of Canadian Academies. Allison Hardisty, CAHS Director This report should be cited as: Canadian Academy of Operations and Executive Assistant to the of Health Sciences, 2015. From Concept to Impact – President assisted the authors in the acquisition 10 Years of Progress of files and data. Inputs were also sought from prior CAHS presidents Martin Schechter (2007-09), Disclaimer: The internet data and information Catharine Whiteside (2009–11) and Thomas Marrie referenced in this report were correct, to the best (2011–13). Any opinions, findings, or conclusions knowledge of the Canadian Academy of Health expressed in this publication are those of the Sciences at the time of publication. Due to the authors, and do not necessarily represent dynamic nature of the internet, resources that the views of their organizations of affiliation are free and publicly available may subsequently or employment. -
Department of Medicine Annual Report 2018-2020 Cover: Dr
Department of Medicine Annual Report 2018-2020 Cover: Dr. Verdu and her Research Team Top row: Dr. Heather Galipeau, Dr. Elena Verdu Middle row: Dr. Xuanyu Wang, Dr. Alba Santiago Bottom row: Dr. Marco Constante, Dr. Josie Libertucci A United Team with a common purpose: Dr. Verdu’s Research Team investigates diet-microbiota In addition to being committed to research excellence, this team interactions in chronic intestinal disorders. The team’s line of is committed to each other and to the wellbeing of others. The research includes: the metabolic activity of gut bacteria on the members of this high performing team have been consistent digestion of the dietary protein and gluten, the role of proteolytic supporters of charity events to raise awareness and funds for imbalance in ulcerative colitis, and the contribution of proteolytic the “Canadian Digestive Health Foundation” and “Crohn’s and bacteria to colonic inflammation. The team also explores Colitis of Canada” research, recently surpassing their target mechanisms through which microbes can modulate intestinal fundraising goal at the last virtual GUTSY Walk 2021event. As a inflammation and mechanisms that could help develop therapies to collective team, they have weathered the COVID-19 pandemic and treat celiac disease, and ulcerative colitis. have come together on this cover to illustrate that their common purpose and “united team” approach has not wavered even in this virtually connected world. Our Goals To facilitate the provision of the highest possible quality of care of the medical diseases of adults, giving appropriate consideration to costs and utilities. To take responsibility for the quality of the education programs offered by McMaster University for physicians in training and practice in the disciplines of general internal medicine and the medical subspecialities and to provide many of the planners and teachers for this broad undertaking. -
NCI Budget Fact Book for Fiscal Year 1996
NCI FACT BOOK National Cancer Institute 1996 U.S. DEPARTMENT NATIONAL INSTITUTES OF HEALTH AND OF HEALTH HUMAN SERVICES The information set forth in this publication is compiled and amended annually by the financial management staff of the National Cancer Institute and is intended primarily for use by members of the Institute, principal advisory groups to the Institute and others involved in the administration and management of the National Cancer Program. Questions regarding any of the information contained herein may be directed to the Financial Management Branch, National Cancer Institute, 9000 Rockville Pike, Bethesda, Maryland, 20892. TABLE OF CONTENTS Page Organization Director's Biography ........................................ 1 Former Directors of the NCI .................................. 2 National Cancer Advisory Board .............................. 3 Division Boards of Scientific Counselors ........................ 4 President's Cancer Panel .................................... 5 Executive Committee Members ............................... 5 Organization Charts: National Cancer Institute ................................... 6 Office of the Director ...................................... 7 Division of Basic Sciences .................................. 8 Division of Clinical Sciences ................................ 9 Division of Cancer Epidemiology and Genetics ................. 10 Division of Cancer Prevention and Control .................... 11 Division of Cancer Treatment, Diagnosis and Centers ............ 12 Division of -
Uot History Freidland.Pdf
Notes for The University of Toronto A History Martin L. Friedland UNIVERSITY OF TORONTO PRESS Toronto Buffalo London © University of Toronto Press Incorporated 2002 Toronto Buffalo London Printed in Canada ISBN 0-8020-8526-1 National Library of Canada Cataloguing in Publication Data Friedland, M.L. (Martin Lawrence), 1932– Notes for The University of Toronto : a history ISBN 0-8020-8526-1 1. University of Toronto – History – Bibliography. I. Title. LE3.T52F75 2002 Suppl. 378.7139’541 C2002-900419-5 University of Toronto Press acknowledges the financial assistance to its publishing program of the Canada Council for the Arts and the Ontario Arts Council. This book has been published with the help of a grant from the Humanities and Social Sciences Federation of Canada, using funds provided by the Social Sciences and Humanities Research Council of Canada. University of Toronto Press acknowledges the finacial support for its publishing activities of the Government of Canada, through the Book Publishing Industry Development Program (BPIDP). Contents CHAPTER 1 – 1826 – A CHARTER FOR KING’S COLLEGE ..... ............................................. 7 CHAPTER 2 – 1842 – LAYING THE CORNERSTONE ..... ..................................................... 13 CHAPTER 3 – 1849 – THE CREATION OF THE UNIVERSITY OF TORONTO AND TRINITY COLLEGE ............................................................................................... 19 CHAPTER 4 – 1850 – STARTING OVER ..... ..........................................................................