DOCSLIB.ORG

April 2007 ASCB Newsletter

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
April 2007 ASCB Newsletter ASCB A P R I L 2 0 0 7 NEWSLETTER VOLUME 30, NUMBER 4 MBC: Eliminate Hogan, Meyerowitz Shapiro to the Printed Journal? Run for ASCB President Present Page 4 Brigid Hogan of Duke Medical Center and Elliot Meyerowitz of the California Institute Porter of Technology/HHMI are running for ASCB 47th ASCB President. The elected candidate will serve on the Society’s Executive Committee Lecture Annual Meeting as President-Elect in 2008 and as ASCB Lucy Shapiro President in 2009. of Stanford Program Brigid Hogan Duke Medical Eight candidates will compete for four three- University Page 8 Center year terms as Councilor. All those elected start School of service on January 1, 2008. Medicine has An email with a link to the Society’s been named NIH Director electronic ballot and candidate biographies Lucy Shapiro by ASCB Criticizes Bush will be sent to regular, postdoctoral, and President emeritus members. Bruce M. Stem Cell Policy The election closes on June 30. Results will Alberts to give the 26th Annual be announced in the July issue of the ASCB Keith R. Porter Lecture. Page 13 Elliot Meyerowitz Newsletter. Her lecture, “Spatial and California 2004 ASCB President Harvey F. Lodish Topological Components of Institute of of the Whitehead Institute for Biomedical Bacterial Cell Cycle Regulatory Inside Technology/ Circuitry,” will be presented HHMI Research served as Nominating Committee Chair; also serving on the Committee were during the 47th ASCB Annual Gary G. Borisy, Joanne Chory, Anthony P. Meeting in Washington, DC, President’s Column 2 Mahowald, Suzanne R. Pfeffer, Laura J. Robles, Pamela A. on December 4. ■ Call for Award Nominations 3 Silver, Masatoshi Takeichi, and Fiona M. Watt. ■ MBC and the Economics of Scientifi c Publishing 4 Candidates for ASCB Council Annual Meeting Program 8 InCytes from MBC 10 Each regular, postdoctoral, and emeritus member will be sent a Dear Labby 12 link to the ASCB election site. Since spam fi lters may pre- Public Policy Briefi ng 13 Ueli Aebi Holly Goodson Kathleen Green Doug vent some messages from be- University of Basel University of Northwestern Lauffenburger University Massachusetts ing received, members are en- WICB Column 16 Notre Dame Feinberg School Institute of couraged to go to www.ascb. of Medicine Technology org to vote. Your member num- ASCB Profi le 18 ber (the same number used to Members in the News 22 access MBC) will enable you to vote, and ensure that each Grants & Opportunities 23 member votes just once. If you do not receive the link and/or Member Gifts 23 do not know your member num- ber, contact the ASCB at (301) Classifed Advertising 23 Aki Nakano Paul Sternberg Clare Waterman- Maria Elena RIKEN Discovery California Storer Zavala 347-9300 or ascbinfo@ascb. Research Institute Institute of The Scripps California State org. ■ Calendar 24 Technology/HHMI Research Institute University The American Society for Cell Biology PRESIDENT’S Column 8120 Woodmont Avenue, Suite 750 Bethesda, MD 20814-2762 Tel: (301) 347-9300 Fax: (301) 347-9310 The Real “Science for Society” [email protected], www.ascb.org Recently, Shirin Ebadi, the Iranian lawyer who the NSF, less than one-fourth of U.S. adults Joan R. Goldberg won the Nobel Peace Prize in 2003 for her hu- were able to explain in their own words what it Executive Director man rights efforts, raised an important question. means to study something scientifically (NSF, Officers How, she wondered, can the U.S. be so short- 2006)? sighted and unwise in its foreign policies when Many scientists would probably answer such Bruce M. Alberts President it is so accomplished in its science? This is a dis- questions by putting the blame on others. But in Robert D. Goldman President-Elect turbing question: Why do we not apply a scien- my opinion, an important explanation for these Mary C. Beckerle Past President tific way of viewing the world paradoxes is our overly narrow Gary E. Ward Treasurer to a broader range of human view of the applicability of Jean E. Schwarzbauer Secretary problems? More narrowly, why scientific skills for society. This Council do we not even apply scientific view causes us to adopt attitudes thinking to the question of how that severely limit the spread of Kerry S. Bloom to teach science? science and its values beyond David R. Burgess our university (and science- John S. Condeelis Using the Tools of based industry) walls. Susan K. Dutcher D. Scott Emr Science Joan R. Goldberg, ex officio My 12 years at the National Making a Science Out Caroline M. Kane Academy of Sciences convinced of Science Education Sandra K. Masur me that the future success of our As a first step, can we make a Barbara J. Meyer complex human societies de- science out of science educa- Timothy J. Mitchison pends on using the tools of sci- tion? As scientists, we are all de- Erin K. O'Shea Anne J. Ridley ence much more broadly to Bruce Alberts voted to collecting and objec- Susan R. Wente create a knowledge base—re- tively evaluating data to build sembling the one that we have a powerful knowledge base in ASCB Newsletter in cell biology—that can be used to guide deci- our particular discipline, whether it is cell biol- is published twelve times per sion-making in many areas of human endeavor. ogy, organic chemistry, or astrophysics. But our year by The American Society for Cell Biology. Thus the National Academies have repeatedly reliance on data often stops there. Our disinter- addressed questions such as “How can we make est in collecting evidence on the learning of stu- Joan R. Goldberg Editor a science out of education?” and “How can we dents and using it to improve our own college John L. Saville Production Manager make a science out of sustainable development?” and graduate school teaching is legendary, and Nancy Moulding Production Assistant The answer is to embed research and research- it explains the current push from some farsight- Kevin Wilson Public Policy Briefing ers of the highest quality into a wide variety of ed colleagues for what they call “scientific teach- Ed Newman Advertising Manager ongoing efforts to improve the human condi- ing” (Handelsman et al., 2004). The ASCB has John Fleischman Science Writer Thea Clarke Editorial Manager tion. But thus far we have failed abysmally in had a major role in promoting these new efforts such tasks. through CBE—Life Sciences Deadlines for submission of There is clear evidence Education (www.lifescied. articles and advertising that our approach to teaching org). Led by Editor-in-Chief materials: science is ineffective. Why do we not apply William B. (Bill) Wood, this Issue Deadline According to the National a scientific way of pioneering, open-access ed- June May 1 Science Foundation (NSF), viewing the world to ucation journal has recently July June 1 more than five million people a broader range of expanded to cover the entire August July 1 in the U.S. work in careers human problems? range of biological sciences, requiring expertise in science and I encourage everyone to ASCB Newsletter ISSN 1060-8982 and technology, including both read it and contribute ar- Volume 30, Number 4 some 600,000 life and physical ticles. April 2007 scientists. How is it possible for such a science- Consider the area that I know best, K– rich society to produce high school graduates 12 science education in the U.S. For many © 2007 The American Society for Cell Biology who, in international comparisons, repeatedly decades, we have spent enormous amounts of rank near the bottom in their understanding time and money on all sorts of projects aimed Postmaster: Send change of address to ASCB Newsletter of science and mathematics? And how can we at improving science education in U.S. school The American Society for Cell Biology explain the fact that, in a survey conducted by districts, including some in San Francisco where 8120 Woodmont Avenue, Suite 750 Bethesda, MD 20814-2762 2 ASCB NEWSLETTER APRIL 2007 I have been personally involved. Along the Ph.D. training. I view this as a great opportuni- way, we have made many mistakes, from which ty. Can we begin to build a new type of scientif- we should have learned a great deal; instead, ic enterprise, one in which universities focus on failures are generally viewed as embarrassments seeding large numbers of highly skilled scientists and swept under the rug. As a result, those throughout society as future leaders in education working to improve education tend to make the research, pre-college teaching, journalism, busi- I am encouraged same mistakes over and over again in different ness, science policy, law, and politics? that we finally seem contexts. We should be ambitious in attempting to to have reached a There is a potential advantage to the highly demonstrate that our scientific way of viewing tipping point in the decentralized education system in the U.S.: It the world can have a profound, beneficial gives rise to a large number of varied approaches impact on a broad range of national and seriousness with toward a common goal. As scientists, we should international policies. A future article in this which most colleges be eager to treat these as “experiments” from series will suggest some possible strategies and universities which to collect data to build a sound basis of by which we might hope to address Ebadi’s are addressing knowledge on which to base future educational challenge. ■ the teaching of efforts. Only by honest, detailed research that —Bruce M. Alberts introductory college extracts the reasons for the many successes and science courses.
Load more

Recommended publications
  • Download Issue
    Cell Circuitry || Science Teaches English || The Chicken Genome Is Hot || Magnets in Medicine SEPTEMBER 2002 www.hhmi.org/bulletin Leading Doublea Life It’s a stretch, but doctors who work bench to bedside say they wouldn’t do it any other way. FEATURES 14 On Human Terms 24 The Evolutionary War A small—some say too small—group of Efforts to undermine evolution education have physician-scientists believes the best science evolved into a 21st-century marketing cam- requires patient contact. paign that relies on legal acumen, manipulation By Marlene Cimons of scientific literature and grassroots tactics. 20 Engineering the Cell By Trisha Gura Adam Arkin sees the cell as a mechanical system. He hopes to transform molecular 28 Call of the Wild biology into a kind of cellular engineering Could quirky, new animal models help scien- and in the process, learn how to move cells tists learn how to regenerate human limbs or from sickness to health. avert the debilitating effects of a stroke? By M. Mitchell Waldrop By Kathryn Brown 24 In front of a crowd of 1,500, Ohio’s Board of Education heard testimony on whether students should learn about intelligent design in science class. DEPARTMENTS 2 NOTA BENE 33 PERSPECTIVE ulletin Intelligent Design Is a Cop-Out 4 LETTERS September 2002 || Volume 15 Number 3 NEWS AND NOTES HHMI TRUSTEES PRESIDENT’S LETTER 5 JAMES A. BAKER, III, ESQ. 34 Senior Partner, Baker & Botts A Creative Influence In from the Fields ALEXANDER G. BEARN, M.D. Executive Officer, American Philosophical Society 35 Lost on the Tip of the Tongue Adjunct Professor, The Rockefeller University UP FRONT Professor Emeritus of Medicine, Cornell University Medical College 36 Biology by Numbers FRANK WILLIAM GAY 6 Follow the Songbird Former President and Chief Executive Officer, SUMMA Corporation JAMES H.
    [Show full text]
  • EMBC Annual Report 2007
    EMBO | EMBC annual report 2007 EUROPEAN MOLECULAR BIOLOGY ORGANIZATION | EUROPEAN MOLECULAR BIOLOGY CONFERENCE EMBO | EMBC table of contents introduction preface by Hermann Bujard, EMBO 4 preface by Tim Hunt and Christiane Nüsslein-Volhard, EMBO Council 6 preface by Marja Makarow and Isabella Beretta, EMBC 7 past & present timeline 10 brief history 11 EMBO | EMBC | EMBL aims 12 EMBO actions 2007 15 EMBC actions 2007 17 EMBO & EMBC programmes and activities fellowship programme 20 courses & workshops programme 21 young investigator programme 22 installation grants 23 science & society programme 24 electronic information programme 25 EMBO activities The EMBO Journal 28 EMBO reports 29 Molecular Systems Biology 30 journal subject categories 31 national science reviews 32 women in science 33 gold medal 34 award for communication in the life sciences 35 plenary lectures 36 communications 37 European Life Sciences Forum (ELSF) 38 ➔ 2 table of contents appendix EMBC delegates and advisers 42 EMBC scale of contributions 49 EMBO council members 2007 50 EMBO committee members & auditors 2007 51 EMBO council members 2008 52 EMBO committee members & auditors 2008 53 EMBO members elected in 2007 54 advisory editorial boards & senior editors 2007 64 long-term fellowship awards 2007 66 long-term fellowships: statistics 82 long-term fellowships 2007: geographical distribution 84 short-term fellowship awards 2007 86 short-term fellowships: statistics 104 short-term fellowships 2007: geographical distribution 106 young investigators 2007 108 installation
    [Show full text]
  • 2019 Annual Report
    BECKMAN CENTER 279 Campus Drive West Stanford, CA 94305 650.723.8423 Stanford University | Beckman Center 2019 Annual Report Annual 2019 | Beckman Center University Stanford beckman.stanford.edu 2019 ANNUAL REPORT ARNOLD AND MABEL BECKMAN CENTER FOR MOLECULAR AND GENETIC MEDICINE 30 Years of Innovation, Discovery, and Leadership in the Life Sciences CREDITS: Cover Design: Neil Murphy, Ghostdog Design Graphic Design: Jack Lem, AlphaGraphics Mountain View Photography: Justin Lewis Beckman Center Director Photo: Christine Baker, Lotus Pod Designs MESSAGE FROM THE DIRECTOR Dear Friends and Trustees, It has been 30 years since the Beckman Center for Molecular and Genetic Medicine at Stanford University School of Medicine opened its doors in 1989. The number of translational scientific discoveries and technological innovations derived from the center’s research labs over the course of the past three decades has been remarkable. Equally remarkable have been the number of scientific awards and honors, including Nobel prizes, received by Beckman faculty and the number of young scientists mentored by Beckman faculty who have gone on to prominent positions in academia, bio-technology and related fields. This year we include several featured articles on these accomplishments. In the field of translational medicine, these discoveries range from the causes of skin, bladder and other cancers, to the identification of human stem cells, from the design of new antifungals and antibiotics to the molecular underpinnings of autism, and from opioids for pain
    [Show full text]
  • Pnas11052ackreviewers 5098..5136
    Acknowledgment of Reviewers, 2013 The PNAS editors would like to thank all the individuals who dedicated their considerable time and expertise to the journal by serving as reviewers in 2013. Their generous contribution is deeply appreciated. A Harald Ade Takaaki Akaike Heather Allen Ariel Amir Scott Aaronson Karen Adelman Katerina Akassoglou Icarus Allen Ido Amit Stuart Aaronson Zach Adelman Arne Akbar John Allen Angelika Amon Adam Abate Pia Adelroth Erol Akcay Karen Allen Hubert Amrein Abul Abbas David Adelson Mark Akeson Lisa Allen Serge Amselem Tarek Abbas Alan Aderem Anna Akhmanova Nicola Allen Derk Amsen Jonathan Abbatt Neil Adger Shizuo Akira Paul Allen Esther Amstad Shahal Abbo Noam Adir Ramesh Akkina Philip Allen I. Jonathan Amster Patrick Abbot Jess Adkins Klaus Aktories Toby Allen Ronald Amundson Albert Abbott Elizabeth Adkins-Regan Muhammad Alam James Allison Katrin Amunts Geoff Abbott Roee Admon Eric Alani Mead Allison Myron Amusia Larry Abbott Walter Adriani Pietro Alano Isabel Allona Gynheung An Nicholas Abbott Ruedi Aebersold Cedric Alaux Robin Allshire Zhiqiang An Rasha Abdel Rahman Ueli Aebi Maher Alayyoubi Abigail Allwood Ranjit Anand Zalfa Abdel-Malek Martin Aeschlimann Richard Alba Julian Allwood Beau Ances Minori Abe Ruslan Afasizhev Salim Al-Babili Eric Alm David Andelman Kathryn Abel Markus Affolter Salvatore Albani Benjamin Alman John Anderies Asa Abeliovich Dritan Agalliu Silas Alben Steven Almo Gregor Anderluh John Aber David Agard Mark Alber Douglas Almond Bogi Andersen Geoff Abers Aneel Aggarwal Reka Albert Genevieve Almouzni George Andersen Rohan Abeyaratne Anurag Agrawal R. Craig Albertson Noga Alon Gregers Andersen Susan Abmayr Arun Agrawal Roy Alcalay Uri Alon Ken Andersen Ehab Abouheif Paul Agris Antonio Alcami Claudio Alonso Olaf Andersen Soman Abraham H.
    [Show full text]
  • Research Organizations and Major Discoveries in Twentieth-Century Science: a Case Study of Excellence in Biomedical Research
    A Service of Leibniz-Informationszentrum econstor Wirtschaft Leibniz Information Centre Make Your Publications Visible. zbw for Economics Hollingsworth, Joseph Rogers Working Paper Research organizations and major discoveries in twentieth-century science: A case study of excellence in biomedical research WZB Discussion Paper, No. P 02-003 Provided in Cooperation with: WZB Berlin Social Science Center Suggested Citation: Hollingsworth, Joseph Rogers (2002) : Research organizations and major discoveries in twentieth-century science: A case study of excellence in biomedical research, WZB Discussion Paper, No. P 02-003, Wissenschaftszentrum Berlin für Sozialforschung (WZB), Berlin This Version is available at: http://hdl.handle.net/10419/50229 Standard-Nutzungsbedingungen: Terms of use: Die Dokumente auf EconStor dürfen zu eigenen wissenschaftlichen Documents in EconStor may be saved and copied for your Zwecken und zum Privatgebrauch gespeichert und kopiert werden. personal and scholarly purposes. Sie dürfen die Dokumente nicht für öffentliche oder kommerzielle You are not to copy documents for public or commercial Zwecke vervielfältigen, öffentlich ausstellen, öffentlich zugänglich purposes, to exhibit the documents publicly, to make them machen, vertreiben oder anderweitig nutzen. publicly available on the internet, or to distribute or otherwise use the documents in public. Sofern die Verfasser die Dokumente unter Open-Content-Lizenzen (insbesondere CC-Lizenzen) zur Verfügung gestellt haben sollten, If the documents have been made available under an Open gelten abweichend von diesen Nutzungsbedingungen die in der dort Content Licence (especially Creative Commons Licences), you genannten Lizenz gewährten Nutzungsrechte. may exercise further usage rights as specified in the indicated licence. www.econstor.eu P 02 – 003 RESEARCH ORGANIZATIONS AND MAJOR DISCOVERIES IN TWENTIETH-CENTURY SCIENCE: A CASE STUDY OF EXCELLENCE IN BIOMEDICAL RESEARCH J.
    [Show full text]
  • Thank You to Our 2016 Donors
    THANK YOU TO OUR 2016 DONORS Lifetime Giving Society Rush Holt and Celeste M. Rohlfing Roger and Terry Beachy Mary E. Clutter The Lifetime Giving Margaret Lancefield Robert L. Smith Jr. Cynthia M. Beall Morrel H. Cohen Society recognizes Alice S. Huang and Daniel Vapnek Gary and Fay Beauchamp Donald G. Comb individuals who have David Baltimore contributed a cumulative Raymond G. Beausoleil Jeffrey A. Cooper total of $100,000 or more $2,500-$4,999 $25,000- $49,999 Nicholas A. Begovich Jonathan C. Coopersmith during the course of their Anonymous, in memory Kenneth A. Cowin involvement of Myrtle Ray Zeiber, Jerry A. Bell and Vincent D’Aco with AAAS. Benjamin C. Hammett Jill Sharon Sheridon, Mary Ann Stepp William H. Danforth Tucker Hake Alan and Agnes Leshner May R. Berenbaum Peter B. Danzig Kathleen S. Berger Edwin J. Adlerman Lawrence H. Linden Margaret M. Betchart Vincent Davisson Stephen and Janelle Ersen Arseven Fodor David E. Shaw and James Bielenberg David H. de Weese Beth Kobliner Shaw David R. Atkinson Richard M. Forester † Dennis M. Bier Jeffrey S. Dean Drs. Larry and Jan Allison Bigbee Sibyl R. Golden and $10,000- $24,999 Baldwin John and Mary Deane the Golden Family Thomas R. and Johanna Amy Blackwell Helena L. Chum George E. DeBoer Rush Holt and K. Baruch Peter D. Blair Hans G. Dehmelt Margaret Lancefield Jonathan Bellack Rita R. and Jack H. Colwell C. John Blankley Charles W. Dewitt Alan and Agnes Leshner Floyd E. Bloom Troy E. Daniels Carla Blumberg Ruth A. Douglas Lawrence H. Linden Fred A.
    [Show full text]
  • Stem Cell Biology
    HIGHLIGHTS AND FUTURE PROSPECTS VASSIE C. WARE, Ph.D. LEHIGH UNIVERSITY MULTIDISCIPLINARY APPROACHES BIOLOGICAL ENGINEERS BIOCHEMISTS MOLECULAR BIOLOGISTS NEUROBIOLOGISTS MICROBIOLOGISTS CHEMISTS CLINICIANS CELL BIOLOGISTS VIROLOGISTS BIOETHICISTS & PHYSICISTS MEDICAL HUMANISTS MECHANICAL ENGINEERS COMPUTER SCIENTISTS PROBLEMS IN BIOSCIENCE Genomics and Genomic Technologies Drug Delivery Ethical and social implications Obesity Cardiovascular Disease Neurological Disease Behavioral disorders Infectious Diseases Stem Cells and Regenerative Medicine Cancer Recent advances: Genomics and Genomic Technologies - understanding microbial genomes for biomedical applications and biofuel/bioremediation applications - drug development prospects - pharmacogenomics Stem Cell Biology - tracking stem cells in the brain to understand neurological disease - understanding disease mechanisms in the laboratory - drug development prospects Ethical Considerations First Bacterial Genome Transplantation Changes One Species To Another (Science, August 2007) Changed one bacterial species, Mycoplasma capricolum into another, Mycoplasma mycoides Large Colony (LC), by replacing one organism’s genome with the other one’s genome. WHY? …“We are committed to this research as we believe that synthetic genomics holds great promise in helping to solve issues like climate change and in developing new sources of energy.” ETHICAL AND SOCIAL CONCERNS? In collaboration with the Center for Strategic & International Studies (CSIS), and the Massachusetts Institute of Technology (MIT),
    [Show full text]
  • Dr. Lucy Shapiro Is a Professor of Developmental Biology at Stanford School of Medicine Where She Holds the Virginia and RESEARCH with IMPACT D.K
    UNIVERSITY LECTURE SERIES ONE SHEET Save the Date: How does a cell execute the many functions that define a living entity? We discovered that robust chemically and genetically based May 5 at 5:30 p.m. ET, Virtual Program logic circuits control cell cycle progression and cell differentiation. A critical question is how these control systems function in time and space within a tiny bacterial cell with just 4,000 genes. Lecture Title: We have observed strong parallels between these “genetic circuits” and familiar engineering circuits. These expanding insights The Living Cell as an Integrated System are providing unprecedented understanding of the asymmetric cell differentiation process essential to producing the diverse organisms found on the Earth. LUCY SHAPIRO Virginia and D.K. Ludwig Professor of Developmental Biology, Stanford University Developmental Biologist Researcher Educator Recipient of the 2020 Dickson Prize in Science “It’s the most exciting thing in the world to be a scientist, because FROM ARTIST TO SCIENTIST you’re like a detective — and what I do is try to understand what Shapiro’s start in scientific research took an unconventional life is by starting with a very, very simple bacterial cell and path. She describes her career journey from artist to scientist understanding the genetic circuitry that control a living thing.” in this profile fromThe Scientist. Her success in the field of — Lucy Shapiro developmental biology is a reminder that an interdisciplinary approach to problem-solving is fundamental to innovation. Dr. Lucy Shapiro is a professor of developmental biology at Stanford School of Medicine where she holds the Virginia and RESEARCH WITH IMPACT D.K.
    [Show full text]
  • HHMI Bulletin May 2009 Vol. 22 No. 2
    HHMI BULLETIN M AY ’09 VOL .22 • NO.02 4000 Jones Bridge Road • Chevy Chase, Maryland 20815-6789 Howard Hu www.hhmi.org BULLETIN g hes Medical Institute HHMI In the Eye of the Beholder This isn’t a pansy or a poppy blossom. It’s a mouse retina, removed and flattened to • show the entire surface of the tissue. The concentrated red staining at the top of the image www.hhmi.or indicates that the cone photoreceptors of the dorsal retina contain high levels of phos- phorylated mTOR protein. Phosphorylation of mTOR is a sign that the cells are healthy and receiving good nutrition. This finding suggests a couple of possi bilities, according to HHMI investigator Connie Cepko. First, dorsal cones may respond differently to their surrounding environment than ventral cones. Or the nutrient supply, oxygen level, and g environmental interactions may differ around the dorsal and ventral cones. Understanding normal cone photoreceptor behavior will help Cepko’s team figure out what goes wrong when cone cells die, as in the sight-robbing disease retinitis pigmentosa (see page 12). DETANGLING DNA ProtEINS CALLED HIStoNES HELP MAINTAIN vol. NuCLEAR OrdER. 22 /no. IN THIS ISSUE Early Career Scientists Claudio Punzo / Cepko lab Mathematic Modeler Mercedes Pascual 02 Science Posse OBSERVATI O NS 49 This array of shells shows obvious variety in shape, color, and size. But another quality can be used to categorize the shells: whether they are dextral (right- coiling), or sinsitral (left-coiling). Their left-right asymmetries can be traced to the same genes that affect which side of the human body different organs are found on, researchers have found.
    [Show full text]
  • Eldrin Lewis, MD, MPH New Chief, Cardiovascular Medicine
    FALL 2019 Donate to the CVI Eldrin Lewis, MD, MPH new Chief, Cardiovascular Medicine Eldrin Lewis, MD, MPH, has been number of leadership roles, both at Brigham and Women's appointed Professor of Medicine and nationally though the American Heart Association, and Division Chief, Cardiovascular serving as Chair of Heart Failure and Transplant and Vice Chair Medicine, Department of Medicine, of the Council in Clinical Cardiology Leadership Committee. effective March 1, 2020. Dr. Lewis Dr. Lewis is a clinician-scientist who specializes in the care succeeds Drs. Tom Quertermous of patients with advanced heart failure. He has extensive and Alan Yeung who have expertise in conducting clinical trials that examine diagnostic successfully led the division as a and therapeutic approaches to heart failure. He has also done collaborative partnership over the innovative work to create systems that incorporate quality last 20 years. of life measures for cardiovascular patients in electronic Dr. Lewis received his BS at Penn health records. His work has been supported by NIH, private State, his MD from the University of Pennsylvania, and an industry, and foundations, and has been published in top tier MPH from the Harvard School of Public Health. He did his medical and cardiovascular journals. Dr. Lewis also has a long internal medicine residency and fellowships in cardiovascular record of successful mentorship, and has been recognized as medicine and advance heart failure and transplant cardiology an outstanding teacher and mentor. at the Brigham and Women's Hospital in Boston. After, Dr. Dr. Lewis will make an outstanding Professor of Medicine and Lewis joined the faculty of Harvard Medical Center and the Chief of the Division of Cardiovascular Medicine.
    [Show full text]
  • Research Organizations and Major Discoveries in Twentieth-Century Science: a Case Study of Excellence in Biomedical Research Hollingsworth, J
    www.ssoar.info Research organizations and major discoveries in twentieth-century science: a case study of excellence in biomedical research Hollingsworth, J. Rogers Veröffentlichungsversion / Published Version Arbeitspapier / working paper Zur Verfügung gestellt in Kooperation mit / provided in cooperation with: SSG Sozialwissenschaften, USB Köln Empfohlene Zitierung / Suggested Citation: Hollingsworth, J. R. (2002). Research organizations and major discoveries in twentieth-century science: a case study of excellence in biomedical research. (Papers / Wissenschaftszentrum Berlin für Sozialforschung, 02-003). Berlin: Wissenschaftszentrum Berlin für Sozialforschung gGmbH. https://nbn-resolving.org/urn:nbn:de:0168-ssoar-112976 Nutzungsbedingungen: Terms of use: Dieser Text wird unter einer Deposit-Lizenz (Keine This document is made available under Deposit Licence (No Weiterverbreitung - keine Bearbeitung) zur Verfügung gestellt. Redistribution - no modifications). We grant a non-exclusive, non- Gewährt wird ein nicht exklusives, nicht übertragbares, transferable, individual and limited right to using this document. persönliches und beschränktes Recht auf Nutzung dieses This document is solely intended for your personal, non- Dokuments. Dieses Dokument ist ausschließlich für commercial use. All of the copies of this documents must retain den persönlichen, nicht-kommerziellen Gebrauch bestimmt. all copyright information and other information regarding legal Auf sämtlichen Kopien dieses Dokuments müssen alle protection. You are not allowed
    [Show full text]
  • Bacterial Chromosome Organization and Segregation
    Downloaded from http://cshperspectives.cshlp.org/ on September 24, 2021 - Published by Cold Spring Harbor Laboratory Press Bacterial Chromosome Organization and Segregation Esteban Toro and Lucy Shapiro Department of Developmental Biology, Beckman Center, Stanford University School of Medicine, Stanford, California 94305 Correspondence: [email protected] Bacterial chromosomes are generally 1000 times longer than the cells in which they reside, and concurrent replication, segregation, and transcription/translation of this crowded mass of DNA poses a challenging organizational problem. Recent advances in cell-imaging technology with subdiffraction resolution have revealed that the bacterial nucleoid is reliably oriented and highly organized within the cell. Such organization is transmitted from one generation to the next by progressive segregation of daughter chromosomes and anchoring of DNA to the cell envelope. Active segregation by a mitotic machinery appears to be common; however, the mode of chromosome segregation varies significantly from species to species. he DNA molecule is a remarkably simple wind around each other. Hence, to create two Tand elegant storage medium for genetic in- separate chromosomes, it is necessary to unlink formation. However, linear encoding of this the original two strands, which, even in the case kind demands an inordinately long molecule, of a bacterial genome, amounts to unwinding and so, bacterial chromosomes are much longer several hundreds of thousands of turns. They than the cells in which they reside. For example, wrote: “Although it is difficult at the moment Caulobacter crescentus packages a 1.3 mm (4.0 to see how these processes occur without every- Mbp) genome in a 2 micron cell. This spatial thing getting tangled, we do not feel that this constraint creates a daunting organizational objection will be insuperable” (Watson and problem that is exacerbated on DNA replica- Crick 1953).
    [Show full text]