January 9, 1990, NIH Record, Vol. XLII, No. 1

Total Page:16

File Type:pdf, Size:1020Kb

January 9, 1990, NIH Record, Vol. XLII, No. 1 Januuy 9, 1990 Yol. XUJ No. I 'The Second U.S. Departnxn1 af Health Beat Thing and Human Senicea A&.utPayda.y" Natiomd. lmtitllta of Heahh Recorid Human Genome Office Attains Center Status By l.eslie Fink NIH's role in the human genome project, when it was formally ei;rablished by 11t:Cretary the worldwide effort ro sort and characterize of health and human se.rvkes Dr. Louis Sul­ the body's entire set of genetic instructions, livan. As an independent center, NCHGR took on new emphasis recently when a sepa­ will n:ceive di.reedy from Congress monies ear­ rate NIH center was established to fund and marked for human genome research which, oversee the work. The new National Center this year, will be about $60 million. The for Human Genome Research (NCHGR), for­ NCHGR ll1 also equivalent to other NIH merly the Office of Human Genome Research instirures in its role in advising the NIH under the NIH din:ctor, will now be equiv­ director on matters relating to the center's alent to other NIH institutes in its authority mission. In addition to being the focus within to award grants and plan and direct scientific NIH for usues relating to human genome research. .research, NCHGR works with other federal Directed by Dr. James D. Watson, the new agencies to coordinate, plan and develop pol­ center will distribute funds for research aimed icy on this project. Pnsidmt •mi Mt:i. 811Sh 11uitri the Clir1ital Cen­ at locating---and then analy:i:ing the chemical NOIGR currently has a staff of about 30 ur DK. 22 to wiJh NIH tmplr,ytt1 and patimtJ structure of. all the genes on the 23 pain of employees and expects to raise that number ht.,ppy hoJidayJ. The [mt /11,,,;/y flisitri a• •<bilt chromosomes contained in human cells. Scien­ eventually to about 40. As deputy director, AIDS Jldlit:nt s11ppo,, g,-OMP and a sllPJMI g,t»1p tists refer to the collection of all the genetic Dr. Elke Jordan oversees the day-to-<lay busi­ for parmtJ of rhiJdrm with AIDS, when reasO#.al information in an organism as its genome. ness of NCHGR, which is housed in the Funds distributed by NOIGR will include Lister Hill Center (Bldg. 38A). gifts wttT ~ha11gu/. 8,uh gaw a lmef •~ in MAs11r AMditorirm, toMChi,rg °" 1hr si111a1ia m grants for individual research projects as well According to Warson, "Gene mapping and Pa1ltl"1tl tl"4 thanking NIH rt1t11rrhm, mregim-1 as work in multidisciplinary centers, and sup­ analysis will be the key tools of biology of the •nd s11ppqrt stafffor thur faring ,jfonJ, par­ port fur graduate and postdoctoral training. 21st century. When finally interpreted," he tintlarly in the 11r1tgglr •g•i,ut AIDS. DHHS Befure NCHGR was established, funds ,ays, "the genetic mesaages encoded within I«nklfJ Dr. Ltmis S11IJU1tt1J and his wif, Gir1gn­ pegged fur human genome research were DNA molecules will provide the ultimate ~ thr p,rsidmt d,,rir1g his 'lliJit. Set administetcd by the National Institute: of Gen• answers to the chemical underpinnings of dttaiJ.s ;. mxl iu,u of the Record. era! Medical Sciences. NCHGR became official on Oct. 1, 1989, January Is Designated 'Remember t/r.e Man ... RellU!mber the Dream' Blood Donor Month Benjamin Hooks To Keynote King Commemorative Program What do victims of a New Year's Eve car The NIH is sponsoring a program in com­ accident, a mother giving birth, a teenager memoration of the birth, life and legacy of with leukemia and a patient undergoing heart Dr. Martin Luther King, Jr. on Friday, Jan. surgery have in common? They arc all poten­ 12 from 11:30 a.m. to 1 p.m. in Masur tial blood recipiems. The list of situations Auditorium, Bldg. 10. The theme of this requiring blood Sttms to be growing every year's program is '"Remember the Man ... day, bur one fact remains the same: there is Remember the Dream." only one source of blood-the volunteer The program will feature Dr. Benjamin L. donor. With the manufiu:t:un: of synthetic Hooks, exrcutive director of the National blood still in the future, voluntarily donated Association for the Advancement of Colored blood is still one of the bm medicines avail­ People (NAACP), where he has served since able for the treatment of a wide range of 1977. He is a well-known and highly effective illnesses. orator, a licensed minister, a businessman and January, National Blood Donor Month, has a lawyer. been set aside as the month to salute the vol­ Prior to assuming directonhip of the unteer blood donors who provide this resource NAACP, Hooks was a commissioner with the and to draw attention to the constant need for federal Communicatioll5 Commis6ion. He was new blood donon. Herc at NIH there ill a cofounder and vice president of the Mutual very strong reminder of the individuals who Federal Savings and Loan Association of need our help. The Oinical Center suppons Memphis for 15 years, from 1955 to 1969, a Hooks haa produced from Memphis and many patients who .require blood either one career he pursued while also working both in hosted his own television program, ComJma­ time or duriog an ex.tended period of time. To law and the ministry. tions ;,. Bladt. and White, coproduced anothrr, n=t these needs, the NIH blood bank (part For several years, Hooks was an as5istant Porty Prmnt Spe."1, and has been a panelist on of the hospital's department of transfusion public defender in Memphis, representing the What ls Yom Faith. He auended l.eMoyne medicine) needs mon: than 40 volunteer blood legal interests of the poor and indigent. He College and Howard University, and received donon every day. practiced general law in Memphis and was his J.D. degree from Depaul University Col­ Modem technology has increased medicine"s later selected as the first black judge in Shelby lege of law in 1948. efficiency of blood usage. Whole blood can be County (Memphu) Criminal Court, wheR he following the keynote address, the D.C. (SN DONOR WION1'H, ,._., ZJ served with dutinccion for Sn'l!ral years. CSee IUNG, ..... 2J page 2 The Record January 9, 1990 DONOR MONTH Lecture Series on Taxes (Continued from Page 1. ) Tax rime is scary enough for Americans; ir can be a nightmare for foreigners working in divided into componcnrs and the patient can the U nited Scares. be given only rhe pare he or she really needs. The Fogarty International Center's Interna­ One blood donation could save three or four tional Services and Communications B ranch is lives. However, this information should nor hosting a free lecture series ro help foreign sci­ leave the impression char the blood supply is entists unravel the U.S. rax system. overflowing. Just the opposire is true. Less The series of ninr sessions will begin J an. rhan 5 percent of che eligible popularion of 12 and run through Apr. 6. The locations and rhe Un iced Scates donates blooJ. New donors time vary. The cal ks will cover federal and are conscancly being soughr. scare annual rerurns, as well as such special This month, the NIH blood bank honors issues as tax crcary benefits. the thousands of donors who have supported The series is open to NIH Visiting Program Clinical Center patients and NIH research Dr. Harry V. Gelboi11. chief of 1he L,1bom1ory of participants, nonimmigrant guest researchers needs. Everyone who has thought of g iving Molec11lar Ca1'Ci11ogenesis , NCJ. /msmted 111•0 hon­ and special volunteers, nonimmigrants on blood is urged co scare out rhe nineties by orary !ec111mhip1 011 a recent trip to japan. He expert or expert consultant appointments, FIC donaring chis month. For more informarion, gave the Nakaso11e Lect11re at the National Cancer scholars-in-residence, flC incernarional or to make an appointment, please call Cemer Resea,rh Jmti111te in Tokyo. spomored by the research fellows and ocher nonimmig ranc sci­ 496-1048. Fo1111datio11 for P,-omotion of Cancer Resem·<'h. 1-le entists working officially at the NIH. The NIH blood bank is ntrrcnd y located in then tn;ve/ed to Sendai 10 present ,m honorary lec­ The ISCB also offers free, private rax con­ temporary quarters on rhe fifth floor of Bldg. t11re jointly sponsored by !he Fo11nda1io11 of Te1hoko su]cacions for NJH foreig n scientists. T he tax I0's D wing. le will move co permanent quar­ Medical S()(iety. The lectures are part of a series of consultant will nor prepare forms, bur will ters on the hospital's new first floor wing am111al prese111atio11s spomored by the fo1111datio11.s i11 advise scienrisrs abom problems and soon ; look for an announcement in the ncog11itio11 of i11divid11al excellence in ca11ce,­ procedures. Record. D t'eSl!Llt'Ch . Check with your intramural administrative office for a copy of the lecture schedule. for more derails about the lecrures, call 496-7357; to sched ule a consulranr appointment, phone KING 496-6166. D (Continued from Page 1. ) Yomh Chorale Alumni C horus will provide musical selections. Edward J ackson, currently director of the D.C. Youth Chorale at the The NIH Record Duke Ellington School of the Arts in W ash­ Pub lished biweekly at Bethesda, Md .. by the Edirorial ington, D.C. , and a voice instructor, will Oix·rarions Brauch, Division of Publi( lnfonnation, fur [he direct the alumni chorus. informar1on of employees of the National li,stitutes of This program is sponsored by the N IH Hcal1h, Departmenr of Health and H uman Services, and Divis ion of Equal Opporrunicy and irs I 990 circulated co nonemp loyees by subscriprion onli• through MLK planning commicree.
Recommended publications
  • Download Issue
    Cell Circuitry || Science Teaches English || The Chicken Genome Is Hot || Magnets in Medicine SEPTEMBER 2002 www.hhmi.org/bulletin Leading Doublea Life It’s a stretch, but doctors who work bench to bedside say they wouldn’t do it any other way. FEATURES 14 On Human Terms 24 The Evolutionary War A small—some say too small—group of Efforts to undermine evolution education have physician-scientists believes the best science evolved into a 21st-century marketing cam- requires patient contact. paign that relies on legal acumen, manipulation By Marlene Cimons of scientific literature and grassroots tactics. 20 Engineering the Cell By Trisha Gura Adam Arkin sees the cell as a mechanical system. He hopes to transform molecular 28 Call of the Wild biology into a kind of cellular engineering Could quirky, new animal models help scien- and in the process, learn how to move cells tists learn how to regenerate human limbs or from sickness to health. avert the debilitating effects of a stroke? By M. Mitchell Waldrop By Kathryn Brown 24 In front of a crowd of 1,500, Ohio’s Board of Education heard testimony on whether students should learn about intelligent design in science class. DEPARTMENTS 2 NOTA BENE 33 PERSPECTIVE ulletin Intelligent Design Is a Cop-Out 4 LETTERS September 2002 || Volume 15 Number 3 NEWS AND NOTES HHMI TRUSTEES PRESIDENT’S LETTER 5 JAMES A. BAKER, III, ESQ. 34 Senior Partner, Baker & Botts A Creative Influence In from the Fields ALEXANDER G. BEARN, M.D. Executive Officer, American Philosophical Society 35 Lost on the Tip of the Tongue Adjunct Professor, The Rockefeller University UP FRONT Professor Emeritus of Medicine, Cornell University Medical College 36 Biology by Numbers FRANK WILLIAM GAY 6 Follow the Songbird Former President and Chief Executive Officer, SUMMA Corporation JAMES H.
    [Show full text]
  • EMBC Annual Report 2007
    EMBO | EMBC annual report 2007 EUROPEAN MOLECULAR BIOLOGY ORGANIZATION | EUROPEAN MOLECULAR BIOLOGY CONFERENCE EMBO | EMBC table of contents introduction preface by Hermann Bujard, EMBO 4 preface by Tim Hunt and Christiane Nüsslein-Volhard, EMBO Council 6 preface by Marja Makarow and Isabella Beretta, EMBC 7 past & present timeline 10 brief history 11 EMBO | EMBC | EMBL aims 12 EMBO actions 2007 15 EMBC actions 2007 17 EMBO & EMBC programmes and activities fellowship programme 20 courses & workshops programme 21 young investigator programme 22 installation grants 23 science & society programme 24 electronic information programme 25 EMBO activities The EMBO Journal 28 EMBO reports 29 Molecular Systems Biology 30 journal subject categories 31 national science reviews 32 women in science 33 gold medal 34 award for communication in the life sciences 35 plenary lectures 36 communications 37 European Life Sciences Forum (ELSF) 38 ➔ 2 table of contents appendix EMBC delegates and advisers 42 EMBC scale of contributions 49 EMBO council members 2007 50 EMBO committee members & auditors 2007 51 EMBO council members 2008 52 EMBO committee members & auditors 2008 53 EMBO members elected in 2007 54 advisory editorial boards & senior editors 2007 64 long-term fellowship awards 2007 66 long-term fellowships: statistics 82 long-term fellowships 2007: geographical distribution 84 short-term fellowship awards 2007 86 short-term fellowships: statistics 104 short-term fellowships 2007: geographical distribution 106 young investigators 2007 108 installation
    [Show full text]
  • 2019 Annual Report
    BECKMAN CENTER 279 Campus Drive West Stanford, CA 94305 650.723.8423 Stanford University | Beckman Center 2019 Annual Report Annual 2019 | Beckman Center University Stanford beckman.stanford.edu 2019 ANNUAL REPORT ARNOLD AND MABEL BECKMAN CENTER FOR MOLECULAR AND GENETIC MEDICINE 30 Years of Innovation, Discovery, and Leadership in the Life Sciences CREDITS: Cover Design: Neil Murphy, Ghostdog Design Graphic Design: Jack Lem, AlphaGraphics Mountain View Photography: Justin Lewis Beckman Center Director Photo: Christine Baker, Lotus Pod Designs MESSAGE FROM THE DIRECTOR Dear Friends and Trustees, It has been 30 years since the Beckman Center for Molecular and Genetic Medicine at Stanford University School of Medicine opened its doors in 1989. The number of translational scientific discoveries and technological innovations derived from the center’s research labs over the course of the past three decades has been remarkable. Equally remarkable have been the number of scientific awards and honors, including Nobel prizes, received by Beckman faculty and the number of young scientists mentored by Beckman faculty who have gone on to prominent positions in academia, bio-technology and related fields. This year we include several featured articles on these accomplishments. In the field of translational medicine, these discoveries range from the causes of skin, bladder and other cancers, to the identification of human stem cells, from the design of new antifungals and antibiotics to the molecular underpinnings of autism, and from opioids for pain
    [Show full text]
  • April 2007 ASCB Newsletter
    ASCB A P R I L 2 0 0 7 NEWSLETTER VOLUME 30, NUMBER 4 MBC: Eliminate Hogan, Meyerowitz Shapiro to the Printed Journal? Run for ASCB President Present Page 4 Brigid Hogan of Duke Medical Center and Elliot Meyerowitz of the California Institute Porter of Technology/HHMI are running for ASCB 47th ASCB President. The elected candidate will serve on the Society’s Executive Committee Lecture Annual Meeting as President-Elect in 2008 and as ASCB Lucy Shapiro President in 2009. of Stanford Program Brigid Hogan Duke Medical Eight candidates will compete for four three- University Page 8 Center year terms as Councilor. All those elected start School of service on January 1, 2008. Medicine has An email with a link to the Society’s been named NIH Director electronic ballot and candidate biographies Lucy Shapiro by ASCB Criticizes Bush will be sent to regular, postdoctoral, and President emeritus members. Bruce M. Stem Cell Policy The election closes on June 30. Results will Alberts to give the 26th Annual be announced in the July issue of the ASCB Keith R. Porter Lecture. Page 13 Elliot Meyerowitz Newsletter. Her lecture, “Spatial and California 2004 ASCB President Harvey F. Lodish Topological Components of Institute of of the Whitehead Institute for Biomedical Bacterial Cell Cycle Regulatory Inside Technology/ Circuitry,” will be presented HHMI Research served as Nominating Committee Chair; also serving on the Committee were during the 47th ASCB Annual Gary G. Borisy, Joanne Chory, Anthony P. Meeting in Washington, DC, President’s Column 2 Mahowald, Suzanne R. Pfeffer, Laura J. Robles, Pamela A.
    [Show full text]
  • Pnas11052ackreviewers 5098..5136
    Acknowledgment of Reviewers, 2013 The PNAS editors would like to thank all the individuals who dedicated their considerable time and expertise to the journal by serving as reviewers in 2013. Their generous contribution is deeply appreciated. A Harald Ade Takaaki Akaike Heather Allen Ariel Amir Scott Aaronson Karen Adelman Katerina Akassoglou Icarus Allen Ido Amit Stuart Aaronson Zach Adelman Arne Akbar John Allen Angelika Amon Adam Abate Pia Adelroth Erol Akcay Karen Allen Hubert Amrein Abul Abbas David Adelson Mark Akeson Lisa Allen Serge Amselem Tarek Abbas Alan Aderem Anna Akhmanova Nicola Allen Derk Amsen Jonathan Abbatt Neil Adger Shizuo Akira Paul Allen Esther Amstad Shahal Abbo Noam Adir Ramesh Akkina Philip Allen I. Jonathan Amster Patrick Abbot Jess Adkins Klaus Aktories Toby Allen Ronald Amundson Albert Abbott Elizabeth Adkins-Regan Muhammad Alam James Allison Katrin Amunts Geoff Abbott Roee Admon Eric Alani Mead Allison Myron Amusia Larry Abbott Walter Adriani Pietro Alano Isabel Allona Gynheung An Nicholas Abbott Ruedi Aebersold Cedric Alaux Robin Allshire Zhiqiang An Rasha Abdel Rahman Ueli Aebi Maher Alayyoubi Abigail Allwood Ranjit Anand Zalfa Abdel-Malek Martin Aeschlimann Richard Alba Julian Allwood Beau Ances Minori Abe Ruslan Afasizhev Salim Al-Babili Eric Alm David Andelman Kathryn Abel Markus Affolter Salvatore Albani Benjamin Alman John Anderies Asa Abeliovich Dritan Agalliu Silas Alben Steven Almo Gregor Anderluh John Aber David Agard Mark Alber Douglas Almond Bogi Andersen Geoff Abers Aneel Aggarwal Reka Albert Genevieve Almouzni George Andersen Rohan Abeyaratne Anurag Agrawal R. Craig Albertson Noga Alon Gregers Andersen Susan Abmayr Arun Agrawal Roy Alcalay Uri Alon Ken Andersen Ehab Abouheif Paul Agris Antonio Alcami Claudio Alonso Olaf Andersen Soman Abraham H.
    [Show full text]
  • Research Organizations and Major Discoveries in Twentieth-Century Science: a Case Study of Excellence in Biomedical Research
    A Service of Leibniz-Informationszentrum econstor Wirtschaft Leibniz Information Centre Make Your Publications Visible. zbw for Economics Hollingsworth, Joseph Rogers Working Paper Research organizations and major discoveries in twentieth-century science: A case study of excellence in biomedical research WZB Discussion Paper, No. P 02-003 Provided in Cooperation with: WZB Berlin Social Science Center Suggested Citation: Hollingsworth, Joseph Rogers (2002) : Research organizations and major discoveries in twentieth-century science: A case study of excellence in biomedical research, WZB Discussion Paper, No. P 02-003, Wissenschaftszentrum Berlin für Sozialforschung (WZB), Berlin This Version is available at: http://hdl.handle.net/10419/50229 Standard-Nutzungsbedingungen: Terms of use: Die Dokumente auf EconStor dürfen zu eigenen wissenschaftlichen Documents in EconStor may be saved and copied for your Zwecken und zum Privatgebrauch gespeichert und kopiert werden. personal and scholarly purposes. Sie dürfen die Dokumente nicht für öffentliche oder kommerzielle You are not to copy documents for public or commercial Zwecke vervielfältigen, öffentlich ausstellen, öffentlich zugänglich purposes, to exhibit the documents publicly, to make them machen, vertreiben oder anderweitig nutzen. publicly available on the internet, or to distribute or otherwise use the documents in public. Sofern die Verfasser die Dokumente unter Open-Content-Lizenzen (insbesondere CC-Lizenzen) zur Verfügung gestellt haben sollten, If the documents have been made available under an Open gelten abweichend von diesen Nutzungsbedingungen die in der dort Content Licence (especially Creative Commons Licences), you genannten Lizenz gewährten Nutzungsrechte. may exercise further usage rights as specified in the indicated licence. www.econstor.eu P 02 – 003 RESEARCH ORGANIZATIONS AND MAJOR DISCOVERIES IN TWENTIETH-CENTURY SCIENCE: A CASE STUDY OF EXCELLENCE IN BIOMEDICAL RESEARCH J.
    [Show full text]
  • Thank You to Our 2016 Donors
    THANK YOU TO OUR 2016 DONORS Lifetime Giving Society Rush Holt and Celeste M. Rohlfing Roger and Terry Beachy Mary E. Clutter The Lifetime Giving Margaret Lancefield Robert L. Smith Jr. Cynthia M. Beall Morrel H. Cohen Society recognizes Alice S. Huang and Daniel Vapnek Gary and Fay Beauchamp Donald G. Comb individuals who have David Baltimore contributed a cumulative Raymond G. Beausoleil Jeffrey A. Cooper total of $100,000 or more $2,500-$4,999 $25,000- $49,999 Nicholas A. Begovich Jonathan C. Coopersmith during the course of their Anonymous, in memory Kenneth A. Cowin involvement of Myrtle Ray Zeiber, Jerry A. Bell and Vincent D’Aco with AAAS. Benjamin C. Hammett Jill Sharon Sheridon, Mary Ann Stepp William H. Danforth Tucker Hake Alan and Agnes Leshner May R. Berenbaum Peter B. Danzig Kathleen S. Berger Edwin J. Adlerman Lawrence H. Linden Margaret M. Betchart Vincent Davisson Stephen and Janelle Ersen Arseven Fodor David E. Shaw and James Bielenberg David H. de Weese Beth Kobliner Shaw David R. Atkinson Richard M. Forester † Dennis M. Bier Jeffrey S. Dean Drs. Larry and Jan Allison Bigbee Sibyl R. Golden and $10,000- $24,999 Baldwin John and Mary Deane the Golden Family Thomas R. and Johanna Amy Blackwell Helena L. Chum George E. DeBoer Rush Holt and K. Baruch Peter D. Blair Hans G. Dehmelt Margaret Lancefield Jonathan Bellack Rita R. and Jack H. Colwell C. John Blankley Charles W. Dewitt Alan and Agnes Leshner Floyd E. Bloom Troy E. Daniels Carla Blumberg Ruth A. Douglas Lawrence H. Linden Fred A.
    [Show full text]
  • Stem Cell Biology
    HIGHLIGHTS AND FUTURE PROSPECTS VASSIE C. WARE, Ph.D. LEHIGH UNIVERSITY MULTIDISCIPLINARY APPROACHES BIOLOGICAL ENGINEERS BIOCHEMISTS MOLECULAR BIOLOGISTS NEUROBIOLOGISTS MICROBIOLOGISTS CHEMISTS CLINICIANS CELL BIOLOGISTS VIROLOGISTS BIOETHICISTS & PHYSICISTS MEDICAL HUMANISTS MECHANICAL ENGINEERS COMPUTER SCIENTISTS PROBLEMS IN BIOSCIENCE Genomics and Genomic Technologies Drug Delivery Ethical and social implications Obesity Cardiovascular Disease Neurological Disease Behavioral disorders Infectious Diseases Stem Cells and Regenerative Medicine Cancer Recent advances: Genomics and Genomic Technologies - understanding microbial genomes for biomedical applications and biofuel/bioremediation applications - drug development prospects - pharmacogenomics Stem Cell Biology - tracking stem cells in the brain to understand neurological disease - understanding disease mechanisms in the laboratory - drug development prospects Ethical Considerations First Bacterial Genome Transplantation Changes One Species To Another (Science, August 2007) Changed one bacterial species, Mycoplasma capricolum into another, Mycoplasma mycoides Large Colony (LC), by replacing one organism’s genome with the other one’s genome. WHY? …“We are committed to this research as we believe that synthetic genomics holds great promise in helping to solve issues like climate change and in developing new sources of energy.” ETHICAL AND SOCIAL CONCERNS? In collaboration with the Center for Strategic & International Studies (CSIS), and the Massachusetts Institute of Technology (MIT),
    [Show full text]
  • Dr. Lucy Shapiro Is a Professor of Developmental Biology at Stanford School of Medicine Where She Holds the Virginia and RESEARCH with IMPACT D.K
    UNIVERSITY LECTURE SERIES ONE SHEET Save the Date: How does a cell execute the many functions that define a living entity? We discovered that robust chemically and genetically based May 5 at 5:30 p.m. ET, Virtual Program logic circuits control cell cycle progression and cell differentiation. A critical question is how these control systems function in time and space within a tiny bacterial cell with just 4,000 genes. Lecture Title: We have observed strong parallels between these “genetic circuits” and familiar engineering circuits. These expanding insights The Living Cell as an Integrated System are providing unprecedented understanding of the asymmetric cell differentiation process essential to producing the diverse organisms found on the Earth. LUCY SHAPIRO Virginia and D.K. Ludwig Professor of Developmental Biology, Stanford University Developmental Biologist Researcher Educator Recipient of the 2020 Dickson Prize in Science “It’s the most exciting thing in the world to be a scientist, because FROM ARTIST TO SCIENTIST you’re like a detective — and what I do is try to understand what Shapiro’s start in scientific research took an unconventional life is by starting with a very, very simple bacterial cell and path. She describes her career journey from artist to scientist understanding the genetic circuitry that control a living thing.” in this profile fromThe Scientist. Her success in the field of — Lucy Shapiro developmental biology is a reminder that an interdisciplinary approach to problem-solving is fundamental to innovation. Dr. Lucy Shapiro is a professor of developmental biology at Stanford School of Medicine where she holds the Virginia and RESEARCH WITH IMPACT D.K.
    [Show full text]
  • HHMI Bulletin May 2009 Vol. 22 No. 2
    HHMI BULLETIN M AY ’09 VOL .22 • NO.02 4000 Jones Bridge Road • Chevy Chase, Maryland 20815-6789 Howard Hu www.hhmi.org BULLETIN g hes Medical Institute HHMI In the Eye of the Beholder This isn’t a pansy or a poppy blossom. It’s a mouse retina, removed and flattened to • show the entire surface of the tissue. The concentrated red staining at the top of the image www.hhmi.or indicates that the cone photoreceptors of the dorsal retina contain high levels of phos- phorylated mTOR protein. Phosphorylation of mTOR is a sign that the cells are healthy and receiving good nutrition. This finding suggests a couple of possi bilities, according to HHMI investigator Connie Cepko. First, dorsal cones may respond differently to their surrounding environment than ventral cones. Or the nutrient supply, oxygen level, and g environmental interactions may differ around the dorsal and ventral cones. Understanding normal cone photoreceptor behavior will help Cepko’s team figure out what goes wrong when cone cells die, as in the sight-robbing disease retinitis pigmentosa (see page 12). DETANGLING DNA ProtEINS CALLED HIStoNES HELP MAINTAIN vol. NuCLEAR OrdER. 22 /no. IN THIS ISSUE Early Career Scientists Claudio Punzo / Cepko lab Mathematic Modeler Mercedes Pascual 02 Science Posse OBSERVATI O NS 49 This array of shells shows obvious variety in shape, color, and size. But another quality can be used to categorize the shells: whether they are dextral (right- coiling), or sinsitral (left-coiling). Their left-right asymmetries can be traced to the same genes that affect which side of the human body different organs are found on, researchers have found.
    [Show full text]
  • Eldrin Lewis, MD, MPH New Chief, Cardiovascular Medicine
    FALL 2019 Donate to the CVI Eldrin Lewis, MD, MPH new Chief, Cardiovascular Medicine Eldrin Lewis, MD, MPH, has been number of leadership roles, both at Brigham and Women's appointed Professor of Medicine and nationally though the American Heart Association, and Division Chief, Cardiovascular serving as Chair of Heart Failure and Transplant and Vice Chair Medicine, Department of Medicine, of the Council in Clinical Cardiology Leadership Committee. effective March 1, 2020. Dr. Lewis Dr. Lewis is a clinician-scientist who specializes in the care succeeds Drs. Tom Quertermous of patients with advanced heart failure. He has extensive and Alan Yeung who have expertise in conducting clinical trials that examine diagnostic successfully led the division as a and therapeutic approaches to heart failure. He has also done collaborative partnership over the innovative work to create systems that incorporate quality last 20 years. of life measures for cardiovascular patients in electronic Dr. Lewis received his BS at Penn health records. His work has been supported by NIH, private State, his MD from the University of Pennsylvania, and an industry, and foundations, and has been published in top tier MPH from the Harvard School of Public Health. He did his medical and cardiovascular journals. Dr. Lewis also has a long internal medicine residency and fellowships in cardiovascular record of successful mentorship, and has been recognized as medicine and advance heart failure and transplant cardiology an outstanding teacher and mentor. at the Brigham and Women's Hospital in Boston. After, Dr. Dr. Lewis will make an outstanding Professor of Medicine and Lewis joined the faculty of Harvard Medical Center and the Chief of the Division of Cardiovascular Medicine.
    [Show full text]
  • Research Organizations and Major Discoveries in Twentieth-Century Science: a Case Study of Excellence in Biomedical Research Hollingsworth, J
    www.ssoar.info Research organizations and major discoveries in twentieth-century science: a case study of excellence in biomedical research Hollingsworth, J. Rogers Veröffentlichungsversion / Published Version Arbeitspapier / working paper Zur Verfügung gestellt in Kooperation mit / provided in cooperation with: SSG Sozialwissenschaften, USB Köln Empfohlene Zitierung / Suggested Citation: Hollingsworth, J. R. (2002). Research organizations and major discoveries in twentieth-century science: a case study of excellence in biomedical research. (Papers / Wissenschaftszentrum Berlin für Sozialforschung, 02-003). Berlin: Wissenschaftszentrum Berlin für Sozialforschung gGmbH. https://nbn-resolving.org/urn:nbn:de:0168-ssoar-112976 Nutzungsbedingungen: Terms of use: Dieser Text wird unter einer Deposit-Lizenz (Keine This document is made available under Deposit Licence (No Weiterverbreitung - keine Bearbeitung) zur Verfügung gestellt. Redistribution - no modifications). We grant a non-exclusive, non- Gewährt wird ein nicht exklusives, nicht übertragbares, transferable, individual and limited right to using this document. persönliches und beschränktes Recht auf Nutzung dieses This document is solely intended for your personal, non- Dokuments. Dieses Dokument ist ausschließlich für commercial use. All of the copies of this documents must retain den persönlichen, nicht-kommerziellen Gebrauch bestimmt. all copyright information and other information regarding legal Auf sämtlichen Kopien dieses Dokuments müssen alle protection. You are not allowed
    [Show full text]