“Opioid” Definition Drug Inclusion and Exclusion List

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“Opioid” Definition Drug Inclusion and Exclusion List

WSHA WSMA Opioid Prescribing Report Medication Inclusion/Exclusion list For purposes of developing WSHA WSMA Opioid Prescribing Report metrics, the following medications tracked in the Prescription Monitoring Program database were included and counted as “opioid prescriptions”: Drug Name ACETAMINOPHEN-CODEINE ASCOMP WITH CODEINE BELLADONNA-OPIUM BUTALB-ACETAMINOPH-CAFF-CODEIN BUTALB-CAFF-ACETAMINOPH-CODEIN BUTALBITAL COMPOUND-CODEINE BUTORPHANOL TARTRATE CARISOPRODOL-ASPIRIN-CODEINE CHERATUSSIN AC CHERATUSSIN DAC CODEINE SULFATE CODEINE-GUAIFENESIN DEMEROL DILAUDID DOLOPHINE HCL DURAMORPH ENDOCET FENTANYL CITRATE FENTORA FIORICET WITH CODEINE FIORINAL WITH CODEINE #3 GUAIATUSSIN AC GUAIFENESIN AC GUAIFENESIN DAC GUAIFENESIN W/CODEINE GUAIFENESIN-CODEINE HYDROCODONE BITARTRATE HYDROCODONE BT-HOMATROPINE MBR HYDROCODONE-ACETAMINOPHEN HYDROCODONE-CHLORPHENIRAMNE ER HYDROCODONE-HOMATROPINE MBR HYDROCODONE-IBUPROFEN HYDROMET HYDROMORPHONE HCL INFUMORPH IOPHEN-C NR LAZANDA LEVORPHANOL TARTRATE LORTAB MEPERIDINE HCL MORPHINE SULFATE NORCO NUCYNTA OPANA OPIUM TINCTURE OXAYDO OXYCODONE HCL OXYCODONE HCL-ASPIRIN OXYCODONE HCL-IBUPROFEN OXYCODONE HYDROCHLORIDE OXYCODONE-ACETAMINOPHEN OXYMORPHONE HCL PENTAZOCINE-NALOXONE HCL PERCOCET PRIMLEV PROMETHAZINE VC-CODEINE PROMETHAZINE-CODEINE PROMETHAZINE-PHENYLEPH-CODEINE ROXICODONE SUBSYS SUFENTANIL CITRATE TRAMADOL HCL TRAMADOL HCL-ACETAMINOPHEN TUSSIGON TUSSIONEX TYLENOL-CODEINE NO.3 TYLENOL-CODEINE NO.4 ULTRACET ULTRAM VICODIN VICODIN ES VICODIN HP VIRTUSSIN AC Other medications, used primarily to treat opioid use disorder, were excluded from analysis: BELBUCA BUNAVAIL BUPRENORPHINE BUPRENORPHINE HCL BUPRENORPHINE-NALOXONE BUTRANS DIPHENOXYLATE-ATROPINE LOMOTIL METHADONE HCL METHADONE INTENSOL METHADOSE PROBUPHINE SUBLOCADE SUBOXONE ZUBSOLV Opioid Liquid and Syrup Conversion Assumptions: Solutions are given orally which lowers the dose efficacy (e.g. 30mg PO = 10mg IV) 1 dose = 5 MEDS = 1 vicodin 5mg tablet Morphine 10MG PO = 10 MED Oxycodone 5 mg PO = 7.5 MED (thus 3.65 is equivalent) Hydrocodone 5MG PO = 5 MED Hydromorphine 1mg PO = 4 MED (thus 1.25 is equivalent) Codein 35MG PO = 5 MED Meperidine 100mg PO = 10 MED .

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Appendix a Common Abbreviations Used in Medication
UNIVERSITY OF AMSTERDAM MASTERS THESIS Impact of Medication Grouping on Fall Risk Prediction in Elders: A Retrospective Analysis of MIMIC-III Critical Care Database Student: SRP Mentor: Noman Dormosh Dr. Martijn C. Schut Student No. 11412682 – SRP Tutor: Prof. dr. Ameen Abu-Hanna SRP Address: Amsterdam University Medical Center - Location AMC Department Medical Informatics Meibergdreef 9, 1105 AZ Amsterdam Practice teaching period: November 2018 - June 2019 A thesis submitted in fulfillment of the requirements for the degree of Master of Medical Informatics iii Abstract Background: Falls are the leading cause of injury in elderly patients. Risk factors for falls in- cluding among others history of falls, old age, and female gender. Research studies have also linked certain medications with an increased risk of fall in what is called fall-risk-increasing drugs (FRIDs), such as psychotropics and cardiovascular drugs. However, there is a lack of consistency in the definitions of FRIDs between the studies and many studies did not use any systematic classification for medications. Objective: The aim of this study was to investigate the effect of grouping medications at different levels of granularity of a medication classification system on the performance of fall risk prediction models. Methods: This is a retrospective analysis of the MIMIC-III cohort database. We created seven prediction models including demographic, comorbidity and medication variables. Medica- tions were grouped using the anatomical therapeutic chemical classification system (ATC) starting from the most specific scope of medications and moving up to the more generic groups: one model used individual medications (ATC level 5), four models used medication grouping at levels one, two, three and four of the ATC and one model did not include med- ications.
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)&F1y3x PHARMACEUTICAL APPENDIX to THE
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Injectable Anesthesia in South American Camelids
INJECTABLE ANESTHESIA IN SOUTH AMERICAN CAMELIDS Thomas Riebold DVM, Diplomate ACVAA Veterinary Teaching Hospital College of Veterinary Medicine Oregon State University Corvallis, Oregon 97331 INTRODUCTION Interest in llamas, and more recently in alpacas, as pets and as breeding and pack animals has led to increased demand for veterinary services for them. While they have some unique species characteristics regarding anesthesia, many of the principles and techniques used in food animal and equine anesthesia also apply to South American camelids. Except for differences in size, anesthetic management of alpacas and llamas is similar. Much like there are species differences between cattle, sheep, and goats in their response to xylazine, it does appear that alpacas require higher doses of sedatives, approximately 10-20%, to obtain the same response that lower doses of sedatives would obtain in llamas. PREANESTHETIC CONSIDERATIONS Consideration for preanesthetic preparation includes fasting, assessment of hematologic and blood chemistry values, venous catheterization, and estimation of bodyweight. The camelid has a stomach divided into three compartments. Therefore, potential complications similar to those of domestic ruminants, regurgitation and aspiration pneumonia, exist during anesthesia. Abdominal tympany as it occurs in anesthetized domestic ruminants does not appear to occur in anesthetized camelids. It is recommended that the animals be fasted 12-18 hours and deprived of water for 8-12 hours. In nonelective cases, this is often not possible and precautions should be taken to avoid aspiration of gastric fluid and ingesta. Fasting neonatal camelids is not advisable because hypoglycemia may result. As in other species, hematologic and blood chemistry values are determined before anesthesia.
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Use of Antitussives After the Initiation of Angiotensin-Converting Enzyme Inhibitors
저작자표시-비영리-변경금지 2.0 대한민국 이용자는 아래의 조건을 따르는 경우에 한하여 자유롭게 l 이 저작물을 복제, 배포, 전송, 전시, 공연 및 방송할 수 있습니다. 다음과 같은 조건을 따라야 합니다: 저작자표시. 귀하는 원저작자를 표시하여야 합니다. 비영리. 귀하는 이 저작물을 영리 목적으로 이용할 수 없습니다. 변경금지. 귀하는 이 저작물을 개작, 변형 또는 가공할 수 없습니다. l 귀하는, 이 저작물의 재이용이나 배포의 경우, 이 저작물에 적용된 이용허락조건 을 명확하게 나타내어야 합니다. l 저작권자로부터 별도의 허가를 받으면 이러한 조건들은 적용되지 않습니다. 저작권법에 따른 이용자의 권리는 위의 내용에 의하여 영향을 받지 않습니다. 이것은 이용허락규약(Legal Code)을 이해하기 쉽게 요약한 것입니다. Disclaimer 약학 석사학위 논문 안지오텐신 전환 효소 억제제 개시 이후 진해제의 사용 분석 Use of Antitussives After the Initiation of Angiotensin-Converting Enzyme Inhibitors 2017년 8월 서울대학교 대학원 약학과 사회약학전공 권 익 태 안지오텐신 전환 효소 억제제 개시 이후 진해제의 사용 분석 Use of Antitussives After the Initiation of Angiotensin-Converting Enzyme Inhibitors 지도교수 홍 송 희 이 논문을 권익태 석사학위논문으로 제출함 2017년 4월 서울대학교 대학원 약학과 사회약학전공 권 익 태 권익태의 석사학위논문을 인준함 2017년 6월 위 원 장 (인) 부 위 원 장 (인) 위 원 (인) Abstract Use of Antitussives After the Initiation of Angiotensin-Converting Enzyme Inhibitors Ik Tae Kwon Department of Social Pharmacy College of Pharmacy, Seoul National University Background Angiotensin-converting enzyme inhibitors (ACEI) can induce a dry cough, more frequently among Asians. If healthcare professionals fail to detect coughs induced by an ACEI, patients are at risk of getting antitussives inappropriately instead of discontinuing ACEI. The purpose of this study was to examine how the initiation of ACEI affects the likelihood of antitussive uses compared with the initiation of Angiotensin Receptor Blocker (ARB) and to determine the effect of the antitussive use on the duration and adherence of therapy in a Korean population.
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Helicidine, Un Extrait Doses May Be Given
1562 Cough Suppressants Expectorants Mucolytics and Nasal Decongestants UK preparations suggest that these doses be given up to a maxi- ◊ References. Ipecacuanha mum of 4 times daily, although in other countries higher total 1. Pons F, et al. L’effect bronchorelaxant de l’helicidine, un extrait doses may be given. d’Helix pomatia, fait intervenir une liberation de prostaglandine Hlavěnkový kořen; Ipecac; Ipecacuana; Ipécacuanha, racine d’; E2. Pathol Biol (Paris) 1999; 47: 73–80. Respiratory disorders. An FDA review of preparations avail- Ipecacuanha Root; Ipecacuanhae radix; Ipekakuána-gyökér; able over-the-counter concluded that guaifenesin was an effec- Preparations Ipekakuananjuuri (ipecacuanha root); Ipekakuanarot (ipecacuan- tive expectorant.1 The use of expectorants for productive cough Proprietary Preparations (details are given in Part 3) ha root); Ipekakuanu˛ šaknys; Korzeń ipekakuany; Raíz de ipecac- 2 uana. is discussed on p.1547. A small study found that guaifenesin Multi-ingredient: Ger.: Original Schneckensirup†. also appeared to reduce cough reflex sensitivity in patients with Ипекакуана upper respiratory-tract infections, which produce a transient in- CAS — 8012-96-2. crease in sensitivity, although it had no effect on cough reflex in ATC — R05CA04; V03AB01. Indanazoline Hydrochloride (rINNM) ⊗ healthy subjects. The mechanism for this effect was unclear. ATC Vet — QR05CA04; QV03AB01. Guaifenesin has been given to patients with altered nasal muco- Hidrocloruro de indanazolina; Indanazolin Hidroklorür; Indana- 3 Pharmacopoeias. In Eur. (see p.vii), Int., Jpn, and US. ciliary clearance associated with HIV infection. zoline, Chlorhydrate d’; Indanazolini Hydrochloridum. 1. Thomas J. Guaiphenesin—an old drug now found to be effective. Eur., Jpn, and US also include a monograph for Prepared Ipecac- Aust J Pharm 1990; 71: 101–3.
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Estonian Statistics on Medicines 2016 1/41
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How to Anesthetize Donkeys for Surgical Procedures in the Field
DRUGS AND ANESTHESIA How to Anesthetize Donkeys for Surgical Procedures in the Field Lori A. Bidwell, DVM, Diplomate ACVA Author’s address: Ross University School of Veterinary Medicine, PO Box 334, St. Kitts, West Indies; e-mail: [email protected]. © 2010 AAEP. 1. Introduction ing a local block where a catheter will be placed and Donkeys are an important part of the work force in making a small skin incision with a surgical blade much of the world. Practitioners working with before placing an intravenous catheter is recom- donkeys in the United States and those participat- mended. Intubation is more difﬁcult because of ing in equitarian initiatives abroad should under- caudal angulation of the larynx, a pharyngeal diver- stand the difference between donkeys and horses in ticulum, excess pharyngeal mucosa, and long paired relation to anesthesia. Although it is tempting to laryngeal saccules. Additionally, nasal intubation 1 treat a donkey like a horse, there are important is complicated by narrow nasal passages. Drug differences in relation to handling and drug doses. metabolism is elevated in donkeys compared with Additionally, it is important to understand alterna- horses, resulting in the use of higher doses and more 2–6 tive anesthetic protocols because a practitioner may frequent dosing intervals. The only known ex- be limited to minimal or alternative drugs when ception to this is the administration of guaifenesin, working in a developing country. which seems to require lower dosing because respi- ratory arrest is easy to achieve when using doses 7 2. Behavior and Physiology appropriate for a horse. A tame donkey can be easy to handle but a feral or minimally handled donkey can be frustrating.
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National OTC Medicines List-2018
National OTC Medicines List – First Edition 2018 NATIONAL OTC MEDICINES LIST First Edition 2018 Foreword According to the French National Agency for Medicines and Health Products Safety (ANSM), Over‐the‐ counter (OTC) drugs are medicines that are accessible to patients in pharmacies, based on criteria set to safeguard patients’ safety. FDA’s Center for Drug Evaluation and Research (CDER) regulates over‐the‐counter (OTC) which are drugs that have been found to be safe and appropriate for use without the supervision of a health care professional such as a physician, and they can be purchased by consumers without a prescription. Due to their therapeutic class, these medicines could be dispensed without physician’s intervention for diagnostic, treatment initiation or maintenance purposes. According to Arcle 43 of the Law No.367 issued in 1994 related to the pharmacy practice, and the amendment of Arcles 46 and 47 by Law No.91 issued in 2010, pharmacists do not have the right to dispense any medicine that is not requested through a unified prescription, unless the medicine is mentioned in a list which is established by the Orders of Pharmacists and Physicians In this regards, the Ministry of Public Health (MoPH) developed the National OTC list, presented it in a scientific, objective, reliable and accessible listingand issued by a Ministerial decision. At this stage, no “convenience size packaging” nor “restriction to a maximum dose” or a “maximum dose per day” or “length of treatment” were considered for some molecules to allow them to be classified as OTC. The list covers medicines that are intended to relief patients from minor to moderate symptoms for a determined period, and procured with the pharmacist’s assistance without the physician’s intervention.
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Guaifenesin, Dextromethorphan, and Phenylephrine
PATIENT & CAREGIVER EDUCATION Guaifenesin, Dextromethorphan, and Phenylephrine This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Brand Names: US Aquanaz [OTC]; Deconex DMX [OTC]; Duravent DM [OTC] [DSC]; Gcon DMX [OTC]; GoodSense Mucus Relief Child [OTC]; GoodSense Mucus/Congest/Cough [OTC]; GoodSense Tussin CF [OTC]; Mucinex Childrens Freefrom [OTC]; Mucinex Cold Childrens [OTC]; Mucinex Congest & Cough Child [OTC] [DSC]; Mucinex Cough & Congest Child [OTC]; Mucinex Fast-Max Congest Cough [OTC]; Mucinex Freefrom Sev Cngst/Cgh [OTC]; Mucinex Junior Cough/Congest [OTC]; NeoTuss- D [OTC] [DSC]; Nivanex DMX [OTC]; Relhist DMX [OTC] [DSC]; Robafen CF Multi- Symptom Cold [OTC]; Robitussin Child Cough/Cold CF [OTC]; Robitussin Multi- Symptom Max [OTC] [DSC]; Robitussin Peak Cold Multi-Sym [OTC]; Robitussin To Go Cough/Cold CF [OTC] [DSC] What is this drug used for? It is used to treat nose stuffiness. It is used to relieve coughing. It is used to thin mucus so it can be taken from the body by coughing. Guaifenesin, Dextromethorphan, and Phenylephrine 1/6 What do I need to tell the doctor BEFORE my child takes this drug? If your child is allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell the doctor about the allergy and what signs your child had. If your child has any of these health problems: Cough with a lot of mucus, a long-term cough caused by smoking or being around smoke, or lung problems like asthma.
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Ipecacuanha Mum of 4 Times Daily, Although in Other Countries Higher Total 1
1562 Cough Suppressants Expectorants Mucolytics and Nasal Decongestants UK preparations suggest that these doses be given up to a maxi- ◊ References. Ipecacuanha mum of 4 times daily, although in other countries higher total 1. Pons F, et al. L’effect bronchorelaxant de l’helicidine, un extrait doses may be given. d’Helix pomatia, fait intervenir une liberation de prostaglandine Hlavěnkový kořen; Ipecac; Ipecacuana; Ipécacuanha, racine d’; E2. Pathol Biol (Paris) 1999; 47: 73–80. Respiratory disorders. An FDA review of preparations avail- Ipecacuanha Root; Ipecacuanhae radix; Ipekakuána-gyökér; able over-the-counter concluded that guaifenesin was an effec- Preparations Ipekakuananjuuri (ipecacuanha root); Ipekakuanarot (ipecacuan- tive expectorant.1 The use of expectorants for productive cough Proprietary Preparations (details are given in Part 3) ha root); Ipekakuanu˛ šaknys; Korzeń ipekakuany; Raíz de ipecac- 2 uana. is discussed on p.1547. A small study found that guaifenesin Multi-ingredient: Ger.: Original Schneckensirup†. also appeared to reduce cough reflex sensitivity in patients with Ипекакуана upper respiratory-tract infections, which produce a transient in- CAS — 8012-96-2. crease in sensitivity, although it had no effect on cough reflex in ATC — R05CA04; V03AB01. Indanazoline Hydrochloride (rINNM) ⊗ healthy subjects. The mechanism for this effect was unclear. ATC Vet — QR05CA04; QV03AB01. Guaifenesin has been given to patients with altered nasal muco- Hidrocloruro de indanazolina; Indanazolin Hidroklorür; Indana- 3 Pharmacopoeias. In Eur. (see p.vii), Int., Jpn, and US. ciliary clearance associated with HIV infection. zoline, Chlorhydrate d’; Indanazolini Hydrochloridum. 1. Thomas J. Guaiphenesin—an old drug now found to be effective. Eur., Jpn, and US also include a monograph for Prepared Ipecac- Aust J Pharm 1990; 71: 101–3.
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Alphabetical Listing of ATC Drugs & Codes
Alphabetical Listing of ATC drugs & codes. Introduction This file is an alphabetical listing of ATC codes as supplied to us in November 1999. It is supplied free as a service to those who care about good medicine use by mSupply support. To get an overview of the ATC system, use the “ATC categories.pdf” document also alvailable from www.msupply.org.nz Thanks to the WHO collaborating centre for Drug Statistics & Methodology, Norway, for supplying the raw data. I have intentionally supplied these files as PDFs so that they are not quite so easily manipulated and redistributed. I am told there is no copyright on the files, but it still seems polite to ask before using other people’s work, so please contact <[email protected]> for permission before asking us for text files. mSupply support also distributes mSupply software for inventory control, which has an inbuilt system for reporting on medicine usage using the ATC system You can download a full working version from www.msupply.org.nz Craig Drown, mSupply Support <[email protected]> April 2000 A (2-benzhydryloxyethyl)diethyl-methylammonium iodide A03AB16 0.3 g O 2-(4-chlorphenoxy)-ethanol D01AE06 4-dimethylaminophenol V03AB27 Abciximab B01AC13 25 mg P Absorbable gelatin sponge B02BC01 Acadesine C01EB13 Acamprosate V03AA03 2 g O Acarbose A10BF01 0.3 g O Acebutolol C07AB04 0.4 g O,P Acebutolol and thiazides C07BB04 Aceclidine S01EB08 Aceclidine, combinations S01EB58 Aceclofenac M01AB16 0.2 g O Acefylline piperazine R03DA09 Acemetacin M01AB11 Acenocoumarol B01AA07 5 mg O Acepromazine N05AA04
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Equine Anesthesia
• EQUINE ANESTHESIA Lyon Lee DVM PhD DACVA Introduction • Higher morbidity and mortality associated with general anesthesia (1:100) in comparison to small animals (1:1000) or human (1: 200,000) • No change of the risk ratio for the last 30 years, but the duration of surgery extended. • Unique anatomic and physiologic characteristics presents additional challenge • More pronounced cardiovascular depression (hypotension and reduced cardiac output) at equipotent MAC than other species such as dogs and cats • The size, weight temperament and tendency to panic of the adult horse introduce the risk of injury to the patient and to the personnel. • Prolonged recumbency is unnatural in the horse • When a horse is placed in dorsal recumbency, the weight of the abdominal contents presses on the diaphragm and limits lung expansion, leading to hypoventilation. If the drugs used to produce anesthesia depress cardiovascular function, these changes will be exaggerated due to a ventilation-perfusion mismatch. Standing chemical restraint and preanesthetic agents • Due to higher risk associated with general anesthesia in this species, standing chemical restraint can offer safer alternative for many procedures • Neuroleptanalgesia (neuroleptics + opioids) or sedative/opioid combination are most popular • Produced by the concurrent administration of a sedative/tranquilizer and a narcotic analgesic (e.g. detomidine and butorphanol; acepromazine and morphine) • Better restraint and analgesia (the combination is synergistic, not merely additive) • Many procedures can be performed which would not be possible with the tranquilizer or sedative alone • Dose sparing effect on both drugs • Better cardiovascular preservation • Can provide satisfactory working condition for minor surgery when combined with local anesthesia • Less expense, less risk, less logistics • This combination can also be effective as preanesthetic medication to produce reliable sedation (e.g.
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