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Proceedings MFHS 2014 Conference 2nd International Conference on MicroFluidic Handling Systems 8.-10. October 2014 University of Freiburg Germany Proceedings 2nd International Conference on MicroFluidic Handling Systems 1 8 { 10 October 2014, University of Freiburg, Germany Welcome to the 2nd International Conference on Microfluidic Handling Systems Dear colleagues, We are pleased to welcome you to the 2nd International Conference on Microfluidic Handling Systems (MFHS 2014) in Freiburg, as a follow-up to the successful first conference in Enschede in 2012. Worldwide, accurate handling – i.e. analysis, dosage, measurement and control – of small and extremely small mass flow rates of both gases and liquids is becoming more and more important, driven by numerous applications. Examples of economically and societally relevant applications are e.g. improvement of medical infusion pump systems, increasing the efficiency of processes that extract oil from oil wells (enhanced oil recovery), systems that measure the energy content (calorific value or Wobbe Index) of natural gas and bio- gas, monitoring of ground water pollution and the production of pharmaceuticals by means of flow chemistry. Whether in analytical instrumentation, flow chemistry, energy, semiconductor industry, food & beverage or life sciences – microfluidic handling systems are facing two major trends: (1) a need for accurate measure- ment and calibration facilities and (2) a need for complete functional systems rather than for the individual components. In the future, the impact of this field of research may become bigger and potentially large target markets may arise, especially when spin-off companies start manufacturing and selling their products, systems or pilot plants. The MFHS 2014 focuses mainly on the technology, components, devices and systems that enable the application in microfluidic systems. It provides an excellent opportunity to bring together scientists and engineers from academia, research institutes and companies to present and discuss the latest results in the field of microfluidic handling systems. The conference goals are to stimulate interaction and knowledge exchange between the delegates in a friendly atmosphere. The most recent developments in the field of microfluidic sensors, actuators, interfaces, fluidic control systems and applications will be presented. We are looking forward to seeing you at the MFHS 2014 conference! Kind regards, Dr. Peter Koltay Dr. Joost Lötters Prof. Gerald Urban Conference Co-chairs 2nd International Conference on MicroFluidic Handling Systems 2 8 { 10 October 2014, University of Freiburg, Germany Conference Committee Chairs Prof. Dr. Gerald Urban Dr. Peter Koltay University of Freiburg, Germany University of Freiburg, Germany IMTEK – Department of Microsystems IMTEK – Department of Microsystems Engineering Engineering Lab for Sensors Lab for MEMS Applications Dr. Joost Lötters University of Twente, The Netherlands Department of Transducers Science and Technology Technical program Committee Prof. Dr. Shuichi Shoji Dr. Klaus Stefan Drese Waseda University, Japan IMM Mainz Faculty of Science and Engineering Germany Prof. Dr. Han Gardeniers Dr. Holger Becker University of Twente, The Netherlands microfluidic ChipShop Mesoscale Chemical Systems Germany Prof. Dr. Miko Elwenspoek Dr. Martin Richter University of Twente, The Netherlands Fraunhofer EMFT Transducers Science and Technology Germany Prof. Dr. Göran Stemme KTH Royal Institute of Technology, Sweden Micro and Nanosystems 2nd International Conference on MicroFluidic Handling Systems 3 8 { 10 October 2014, University of Freiburg, Germany Conference sponsors In cooperation with 2nd International Conference on MicroFluidic Handling Systems 4 8 { 10 October 2014, University of Freiburg, Germany Program Wednesday, 8th of October 2014 17:00 { 18:00 Registration 18:00 { 21:00 Welcome reception Thursday, 9th of October 2014 08:00 { 09:00 Registration 09:00 { 09:15 Welcome & announcements 09:15 { 09:40 Invited talk 1 Smart Reagent Dosing - Novel Cartridge Concept for Highly Precise Dispensing of IVD Reagents down to the sub-µL Range Dr. J¨urgenSpinke Director Enabling System Technologies Roche Diagnostics GmbH, Germany 09:40 { 11:00 Session 1: Overview of the Field 11:00 { 11:30 Coffee break & exhibition 11:30 { 12:50 Session 2: Sensors 12:50 { 14:00 Lunch 14:00 { 15:20 Session 3: Actuators 15:20 { 15:45 Coffee break & exhibition 15:45 { 16:15 Invited talk 2 Lab on Chip for separations Prof. Dr. Andreas Manz Head of Research KIST Europe (Korea Institute of Science and Technology Europe Forschungsgesellschaft mbH), Germany 16:15 { 18:30 Poster session & exhibition 19:00 Conference dinner 20:30 Evening lecture 2nd International Conference on MicroFluidic Handling Systems 5 8 { 10 October 2014, University of Freiburg, Germany Friday, 10th of October 2014 08:00 { 09:00 Registration 09:00 { 09:15 Welcome & announcements 09:15 { 09:40 Invited talk 3 (Multi-)Infusion: challenges and technical solutions for medication safety Dr. Annemoon Timmerman Clinical Physicist and Patient Safety Officer Faculty of Medicine (UMC), Utrecht University, The Netherlands 09:40 { 11:00 Session 4: Fluidic Control Systems 11:00 { 11:30 Coffee break & exhibition 11:30 { 12:50 Session 5: Applications 12:50 Closure of the conference, Best paper / poster award and Next Conference 13:15 { 14:00 Lunch 15:00 { 17:00 Optional: lab tour at HSG-IMIT, IMTEK and BioFluidix 2nd International Conference on MicroFluidic Handling Systems 6 8 { 10 October 2014, University of Freiburg, Germany Session A (Thursday 09:40) 09:40 { 09:55 { A01 PRIMARY STANDARD FOR NANOFLOW RATES Peter Lucas1, Harm Tido Petter1, Wouter Sparreboom2, Joost L¨otters2 1VSL, Netherlands; 2Bronkhorst High-Tech, Netherlands 09:55 { 10:10 { A02 A COMPACT MICRO CORIOLIS MASS FLOW SENSOR WITH FLOW BYPASS FOR A MONOPROPELLANT MICRO PROPUL- SION SYSTEM Jarno Groenesteijn1, Marcel Dijkstra1, Theo S.J. Lammerink1, Joost C. L¨otters1;2, Remco J. Wiegerink1 1MESA+ Institute for Nanotechnology, University of Twente, Enschede, The Netherlands; 2Bronkhorst High-Tech BV, Ruurlo, The Netherlands 10:10 { 10:25 { A03 PERISTALTIC MICROPUMP WITH INTEGRATED AC- TIVE DAMPING Axel Schumacher1, Martin G¨otz1, Gerhard Kattinger1, J¨urgenMerz1, Simon Herrlich1, Sven Spieth1, Roland Zengerle1;2 1HSG-IMIT, Villingen-Schwenningen, Germany; 2IMTEK, University of Freiburg, Frei- burg, Germany 10:25 { 10:40 { A04 CONTACTLESS BOILING: A WAY TO IMPROVE THE RELIABILITY OF MICROFLUIDIC PROCESSES? Cor Maria Rops1, Balkrishna Patankar2, Gert Jan Snijders3, Cees v/d Geld2 1TNO technical sciences, Netherlands, The; 2Eindhoven university of Technology, Nether- lands, The; 3Bronkhorst High-Tech BV, Netherlands, The 10:40 { 10:55 { A05 3D PRINTED UNIBODY LAB-ON-A-CHIP INTEGRA- TION German Comina, Anke Suska, Daniel Filippini Link¨opingUniversity, Sweden 2nd International Conference on MicroFluidic Handling Systems 7 8 { 10 October 2014, University of Freiburg, Germany Session B (Thursday 11:30) 11:30 { 11:45 { B01 REAL-TIME COMPOSITION DETERMINATION OF GAS MIXTURES Egbert van der Wouden1, Joost L¨otters1;2 1Bronkhorst High-Tech B.V., the Netherlands; 2University of Twente, Transducers Sci- ence and Technology 11:45 { 12:00 { B02 METHOD FOR THE DETERMINATION OF THE THER- MAL PROPERTIES OF GASES UNDER FLOW CONDITIONS Diego Fernando Reyes-Romero1;2, Gerald Urban1 1University of Freiburg, Germany; 2IST AG, Switzerland 12:00 { 12:15 { B03 MICRO FLOW STANDARD FOR STEADY AND PUL- SATING FLOW Hugo Bissig, Martin Tschannen, Marc de Huu Federal Institute of Metrology METAS, Switzerland 12:15 { 12:30 { B04 DETECTION OF GAS KIND AND FLOW SPEED USING THERMAL FLOW SENSORS WITH DC EXCITATION IN A FLOWING FLUID Christoph J. Hepp1, Florian T. Krogmann1, Gerald A. Urban2 1Innovative Sensor Technology IST AG, Switzerland; 2University of Freiburg, Freiburg Institute for Advanced Studies, Freiburg, Germany 12:30 { 12:45 { B05 CALORIMETRIC FLOW SENSOR CHIP BASED ON SUR- FACE CHANNEL TECHNOLOGY Wouter Sparreboom1, Egbert van der Wouden1, Theo Lammerink2, Joost L¨otters1;2 1Bronkhorst High-Tech B.V., Ruurlo, The Netherlands; 2University of Twente, Transduc- ers Science and Technology, Enschede, The Netherlands 2nd International Conference on MicroFluidic Handling Systems 8 8 { 10 October 2014, University of Freiburg, Germany Session C (Thursday 14:00) 14:00 { 14:15 { C01 STARJET-BASED, PNEUMATICALLY ACTUATED LIQ- UID METAL DROPLET PRINTING AT UP TO 500 ◦C Bj¨orn Gerdes1, Nils Lass1, Lutz Riegger1;2, Roland Zengerle1, Peter Koltay1;2 1IMTEK University Freiburg, Germany; 2BioFluidix GmbH 14:15 { 14:30 { C02 DYNAMIC BEHAVIOUR OF A PIEZOELECTRIC MI- CROPUMP ACTUATOR Christoph Werner Jenke, Miriam K¨ohn,Martin Wackerle, Christoph Kutter, Martin Richter Fraunhofer EMFT, Germany 14:30 { 14:45 { C03 A DISPOSABLE, DISPENSING VALVE FOR NON-CON- TACT MICROLITER APPLICATIONS IN 96-WELL PLATE FORMAT Sabrina Kartmann1, Andreas Ernst1;2, Roland Zengerle1, Peter Koltay1;2 1IMTEK, University of Freiburg, Freiburg, Germany, Germany; 2BioFluidix GmbH, Frei- burg, Germany 14:45 { 15:00 { C04 VOLUME CONTROLLABLE SEQUENTAIL GENERA -TION OF THREE DIFFERENT REAGENTS INCUBATED IN MICRO DROPLETS FOR DIGITAL FLOW SYNTHESIS Afshan Jamshaid1;3, Dong Hyun Yoon1, Tetsushi Sekiguchi2, Shuichi Shoji1 1Waseda University, Japan,; 2Nano Technology Research Center, Waseda University To- kyo, JAPAN; 3Department of Physics, Syed Baber Ali School of Science & Engineering, Lahore University of Management Sciences(LUMS), Pakistan 15:00 { 15:15 { C05 DECOUPLED MICROFLUIDIC FLUID
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