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30 JUNE - 3 JULY 2019 Reliable Mycobacteria Diagnostics General Information

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30 JUNE - 3 JULY 2019 Reliable Mycobacteria Diagnostics General Information 30 JUNE - 3 JULY 2019 Reliable Mycobacteria Diagnostics General information NEW: FluoroType® MTBDR – The 1st LiquidArray • Novel technology: The test system is based on the innovative LiquidArray technology. Venue * Social Media It thus enables reliable MDR-TB diagnostics within 2.5 hours only. The Westin Valencia Twitter: #ESMVal19 • True MDR-TB testing: Resistances to both first-line drugs, rifampicin and isoniazid, are reliably identified, as well as mono-resistances. Amadeo de Saboya, 16 Facebook: @ESMyco • Reliable results: The assay can detect silent mutations within the rpoB gene and 46010 Valencia therefore allows confidence when testing for resistance. +34 963 62 59 00 Delegate list and abstracts Useful venue facts Electronic copies of the delegate list and the abstracts are available in ‘My Mycobacteria Product Series: Rapid, easy-to-use and cost-effi cient! • 500m from metro station Aragon * Congress Materials’ in your ESM Perfect for TB screening FluoroType® MTB • Direct line from airport (metro online account. Perfect for MDR- / XDR-TB screening FluoroType® MTBDR, GenoType MTBDRplus / sl Alameda * - 25 minutes) Evaluation and certificate Perfect for NTM differentiation GenoType CMdirect, GenoType Mycobacterium CM / AS, • Direct line from North Station GenoType NTM-DR (metro Xativa * – 5 minutes) of attendance • 1 change from Joaquin Sorolla station We hope you enjoy the ESM annual (15 minutes) congress. We really value your feedback and would be grateful if you could www.hain-lifescience.de Registration and information complete the survey, which you will be desk sent by email after the congress. You will be able to download your certificate of Located at the congress entrance of attendance from your online account the hotel. from 15 July. Congress registration will open at 12:00 on Sunday 30 June and be open every For urgent enquiries day until Wednesday 3 July at 13:00. Please call Gaëlle Jamar, ESM Event DRIVING COMPREHENSIVE AND EFFECTIVE SOLUTIONS IN THE FIGHT TO END TB Wi-Fi access Manager: +44 7766 475379 [email protected] Network: Westin BD Sputum Collection Usuario / login: ESM2019 System BD BBL™ Mycoprep, BD BBL™ BD Epicenter™ Data Acid Fast and Fluorescent Stains Contraseña / password: ESM2019 Management System and BD BBL™ Prepared Media with BD EpiCenter™ TB-eXiST Individual Susceptibility Testing* From specimen collection to Come fi nal result, BD is here to support * See map on inside back cover your M. tuberculosis and other and visit mycobacteria testing needs SIRE and PZA fully BD booth ! automated primary DST BD MAX™ Automated with BD BACTEC™ MGIT™ Molecular System Systems BD MGIT™ TBcID Identification Test* *Not available for sale in the United States BD BACTEC™ MGIT™ Systems bd.com Products are CE marked in compliance with the European In Vitro Diagnostic Medical Device Directive 98/79/EC. BD, the BD Logo and BD Bactec, BD BBL, BD Epicenter, BD Max, and BD MGIT, are trademarks of Becton, Dickinson and Company. © 2019 BD and its subsidiaries. All rights reserved. XEUR5389-19 ESM 40th Annual Congress 2019 Valencia, Spain AD. UNION.indd 1 29/05/2019 12:10 Welcome address biology and their translational potential to We hope you enjoy this meeting. innovative control tools. It is our great pleasure and honour Best regards, Valencia is the third most populous city th in Spain and, as a result of being one of to welcome you to the 40 Annual the largest cities in Europe during the XIV century and a prominent Mediterranean trading route, Valencia today sports a Daniela M. Cirillo (President) Congress of the European Society rich and diverse architectural and cultural landscape. The city is also well known of Mycobacteriology as the birthplace of the paella, which can be enjoyed on one of the city’s many Iñaki Comas (Local) beautiful beaches. We are not only looking forward to a stimulating congress, but also to friendly and casual get-togethers in this beautiful environment. Mireia Coscolla (Local) Last year saw the first UN General starting to see promising results in the Assembly High-level Meeting on Ending vaccine field. TB. The outcome of the meeting put The ESM is a forum where not only state- the spotlight on the need to speed up of-the-art but also incipient research lines the adoption of the 2030 Agenda for are presented and shared. In order to Sustainable Development by increasing make progress in science, two conditions financial support from countries and need to be fulfilled: the availability of industry, and by intensifying research funds, and the field of research being into new tools for tuberculosis control. attractive to young and talented scientists. ESM is committed to the achievement of ESM has been instrumental in increasing these goals through full alignment with the critical mass of basic and clinical the objectives of the European and global scientists dedicated to this field of TB research agenda, and by enabling research and is committed to increasing technology and knowledge transfer their retention in the field by fuelling their to those countries where tuberculosis scientific interests. represents an alarming public health issue. The ESM 2019 programme will address After years of stagnation, the pipeline emerging issues like biomarkers, whole With special thanks to for promising TB diagnostics is now genome based diagnostics, epidemiology increasingly within reach. We expect that of tuberculosis and non-tuberculosis tests for incipient TB, biomarkers suitable mycobacteria, new treatment regimens for point of care diagnosis, and next- for MDR-TB, and ethical aspects of generation sequencing-based diagnostics whole genome sequencing. At the same for MDR-TB will become available within time, it will cover state-of-the-art topics the next few years. In addition, we are on fundamental host and pathogen ESM 40th Annual Congress 2019 Valencia, Spain ESM 40th Annual Congress 2019 Valencia, Spain Programme Programme Sunday 30 June Sunday 30 June 12:00 Registration 17:30- Opening session and awards 20:00 Chairs: Daniela M Cirillo, Iñaki Comas 14:00- Workshop on host pathogen evolution 17:30-17:40 Welcome from the organiser 16:00 Chairs: Mireia Coscollá, University of Valencia; Iñaki Comas, Biomedicine Institute of Valencia (IBV) Bouke de Jong, Institute of Tropical Medicine, Antwerp 17:40-18:00 Opening words from the President 14:00-14:30 GL01 Daniela M Cirillo, San Raffaele Scientific Institute, Milan Dissecting the genetic and evolutionary determinants of immune response variation in humans 18:00-18:45 GL04: Special Lecture Lluis Quintana Murci, Institut Pasteur, Paris What have we learned from the CRyPTIC consortium? Derrick Crook, University of Oxford 14:30-15:00 GL02 What can we learn from ancient horizontal gene transfer in 18:45-19:15 Presentation of Gertrud Meissner Award M. tuberculosis? by Stefan Nieman, Research Center Borstel FZB Olivier Neyrolles, IPSB, Toulouse 19:15-19:45 Presentation of Gardner Middlebrook Award 15:00-15:30 GL03 by Salman Siddiqi, BD Mycobacterial and host determinants of TB granuloma necrosis Antonio Pagan, University of Cambridge Welcome reception at the Palau Alameda * 20:15 (Paseo Alameda corner with Arquitecto Mora, 2 -) * See map on inside back cover 15:30-16:00 OR01 The impact of PE-PPE secretion on the evolution of the Mycobacterium tuberculosis complex Monday 1 July Louis Ates, Amsterdam UMC, University of Amsterdam 09:00- Biology of the host 16:00- Industry symposium 10:30 Chairs: Pere Joan Cardona, Institut Germans Tries i Pujol, Valencia; 17:00 Alexander Apt, Central Tuberculosis Research Institute, Moscow 16:00-16:30 FT MTBDR VER2.0: LiquidArray technology predicts 09:00-09:30 GL05 resistance to rifampicin and isoniazid with high Non-classical innate and adaptive immunity in host defence against accuracy in clinical specimens Mycobacterium tuberculosis in humans Anzaan Dippenaar, DST-NRF Centre of Excellence for Tom Ottenhoff, Leiden University Medical Centre Biomedical Tuberculosis Research | SAMRC Centre for Tuberculosis Research, Pretoria 09:30-09:50 OR02 Mycobacterium tuberculosis modulates sialylation in the lung with an 16:30-17:00 TB control: issue and role of the diagnostic laboratory impact on disease susceptibility in a tertiary care university hospital Kaori Fonseca, i3S, University of Porto Onya Opota, CHUV centre hospitalier universitaire vaudois 09:50-10:10 OR03 17:00- The genetic architecture of the dynamic immune response to 17:30 Coffee break M. tuberculosis infection in human macrophages Joaquín Sanz, Institute BIFI for Bio-computation and Physics of Complex Systems, University of Zaragoza ESM 40th Annual Congress 2019 Valencia, Spain ESM 40th Annual Congress 2019 Valencia, Spain Programme Programme Monday 1 July Monday 1 July 10:10-10:30 OR04 14:00- Poster session I TNF-alpha antagonists differentially induce TGF-beta1-dependent 15:00 Odd numbered posters (P001, P003, P005, P007 etc) Mycobacterium tuberculosis reactivation in a human, in vitro granuloma model Ainhoa Arbués Arribas, Swiss Tropical and Public Health Institute, Basel 15:00- Transmission 10:30- Coffee break 18:00 Chairs: Conor Meehan, University of Bradford; 11:00 Rana Jajou, National Institute for Pubic Health and the Environment RIVM, Bilthoven 11:00- One Health 12:10 Chairs: Thomas Kohl, Research Center Borstel FZB; 15:00-15:30 GL08 Jesús Gonzalo Asensio, University of Zaragoza Ten years and two thousand genomes: Insights from TB WGS in British Columbia, Canada 11:00-11:30 GL06 Jennifer Gardy, University of British Columbia’s School of
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