5Th Ovarian Cancer Consensus Conference

5th Ovarian Cancer Consensus Conference

November 6-9, 2015 Tokyo, Japan 5th Ovarian Cancer Consensus Conference

Tokyo Tower

Zojo-ji temple Shibuya Jikei University Roppongi

Senso-ji temple

Tokyo Sky Tree 5th Ovarian Cancer Consensus Conference

• Hosts: JGOG Supported by JSOG, JSGO, JSMO

• Chairs: K.Ochiai (JGOG), A.Okamoto (JGOG), G.Stuart (NCIC CTG)

• Scientific Planning Committee: D.Aoki (JGOG), M.Bookman (GOG), K.Fujiwara (GOTIC), A.Gonzalez (GEICO), P.Harter (AGO-De), JW.Kim (KGOG), J.Ledermann (MRC-NCRI), E.Pujade-Lauraine (GINECO), M.Quinn (ANZGOG)

• Rapporteurs: J.McGee (NCIC CTG), A.Karam (COGI), A.Leary (GINECO), M.Wilson (ANZGOG)

• Organization Committee: M.Bacon (GCIG), T.Takenaga (JGOG)

5th Ovarian Cancer Consensus Conference

 Venue:  Jikei University School of Medicine  Toranomon Hills

 Accommodation: The Prince Park Tower Tokyo  http://www.princehotels .com/en/parktower/

5th Ovarian Cancer Consensus Conference

Venue-1

University Building 1

Tokyo Tower [1] The Jikei University School of Medicine 3-25-8, Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, JAPAN -3F Lecture Room, Daigaku Ichigou-kan building (Nov. 7 & 9) -Official website (Eng.) http://www.jikei.ac.jp/eng/index.html 5th Ovarian Cancer Consensus Conference

Venue-2

The Jikei Univ. Building 1

Tokyo Tower [2] Toranomon Hills 1-23-3, Toranomon, Minato-ku, Tokyo, 105-6305, JAPAN -4F Hall-B, 5F Meeting Room 3+4 (Nov. 8 &9, 2015) -Official website (Eng.) http://forum.academyhills.com/toranomon/en/ 5th Ovarian Cancer Consensus Conference

 Accommodation Toranomon VENUE 2 Hills The Jikei Univ.

VENUE 1

The Prince Park Tower Tokyo Tokyo Tower 4-8-1, Shibakoen, Minato-ku, Tokyo, 105-8563, JAPAN -Tel: +81 3-5400-1111 -Official website(Eng.) http://www.princehotels.com/en/parktower/ Conference Venue and Accommodation Access from Narita Airport

Narita International Airport

The Jikei University From Narita (NRT) The easiest way to access the hotel is to use the Airport Limousine Bus which takes you directly to the hotel or to the major stations in Tokyo. To “The Prince Park Tower” Hotel 4-8-1 Shibakoen Minato-ku,Tokyo 105-8563 ‎/ Tel: +81-(0)3-5400-1111 The Prince Park Tower Hotel Map http://www.princehotels.com/content/en/parktower/media_file_678_1.pdf Transportation from Narita Airport (NRT) Depending on the traffic, 90-130 minutes, Airport Limousine Bus*(bound for By Bus Shiba area) will take you directly to the hotel [¥ 3,100] ; refer to timetable-#1

1. Narita Express (JR Line)[¥3,020/¥4,560(Green Car as the 1st class)] (1) Narita Airport→Tokyo Station (90min)→Hotel (taxi 12min.) [approx. ¥1,540] (2) Narita Airport→Tokyo Station (90min)→Hamamatsucho Station (JR By Train Yamanote Line bound for Shinagawa, Shibuya 5min.)→Hotel (taxi 5min.) [¥730] (3) Narita Airport→Tokyo Station (90min)→Hamamatsucho Station (JR Yamanote Line bound for Shinagawa, Shibuya 5min.)→Hotel (Shuttle Bus 20min.) [Free] Conference Venue and Accommodation Access from Haneda Airport

The Jikei University

The Prince Park Tower Hotel

From Haneda (HND) The easiest way to the center of Tokyo is to take the Tokyo Monorail bound for Hamamatsucho Station. To “The Prince Park Tower” Hotel Haneda Airport 4-8-1 Shibakoen Minato-ku,Tokyo 105-8563 ‎/ Tel: +81-(0)3-5400-1111 Map http://www.princehotels.com/content/en/parktower/media_file_678_1.pdf Transportation from Haneda Airport (HND) About 20 minutes by Tokyo Monorail to Hamamatsucho Station [ ¥490] By From Hamamatsucho Station Monorail 1. 2.5 minutes by Taxi [¥730] 2. 20 minutes Free Shuttle bus Participants

• Chair, co-chairs, scientific committee: 12 • Delegates of member groups (2 for 28 groups*) : 54 *: 2 duplicate with Supportive Care Plenary Session Presenter • Pathologists: 2 D.Millan (SGCTG), S.Silverberg (JGOG) • Statisticians: 2 BH.Nam (KGOG), A.Reuss (AGO-De) • Supportive Care Plenary Session Presenter: 2 • Guest: 1 A.DuBois (AGO) • Industry Partners: 11 (9 companies)

• Administration: 7 • Rapporteurs: 4 • Room supporters: 4

• Total: 99 TOPICS

 Group A/ Individualized Therapy and Patient Factors Chairs: P.Harter and M.Bookman

 Group B/ First Line Intervention Chairs: J.Ledermann and JW.Kim

 Group C/ Rare Tumors (future approaches) Chairs: M.Quinn, K.Fujiwara

 Group D/ Recurrent disease Chairs: E.Pujade-Lauraine and D.Aoki

Group A

Theme Individualized Therapy and Patient Factors Date / Time 7th November, 2015 / 10:00 a.m. ~ 11:30 a.m. Room Jikei 3F Lecture Room Co-Chairs P.Harter & M.Bookman

What are the most important factors (clinical, pathologic, and molecular) to be evaluated prior to therapy, for stratification and/or treatment selection? What are the markers/targets to be evaluated prior to therapy? 10:00 A1 Front-line Presenter: C.Marth Discussant: I.McNeish 10:30 A2 Recurrent Presenter: R.Mannel Discussant: A.Poveda Are there specific considerations for special patient subpopulations? 11:00 A3 Subpopulations Presenter: F.Hilpert Discussant: K.Hasegawa Group B

Theme First line Intervention Date / Time 7th November, 2015 / 11:30 a.m. ~ 1:00 p.m. Room Jikei 3F Lecture Room Co-Chairs J.Ledermann & JW Kim

11:30 B1 What defines the clinical subgroups that Presenter: J.Sehouli should be used for comparator trials? Discussant: K.Lu eg - neoadjuvant, no residual disease, residual disease; ip therapy; those requiring antiangiogenic therapy; BRCAm ? 12:00 B2 What different control arms could be Presenter: C.Gourley considered for trials of first-line therapy? Discussant: N.Katsumata 3-weekly carboplatin/paclitaxel; bevacizumab; weekly paclitaxel; ip regimen;? 12:30 B3 What should the endpoints be for first line Presenter: M.Friedlander trials? Discussant: BH.Nam eg - OS versus PFS and PFS2 for maintenance trials Group C

Theme Rare Tumours (future approaches) Date / Time 7th November, 2015 / 2:00 p.m. ~ 3:30 p.m. Room Jikei 3F Lecture Room Co-Chairs M.Quinn & K.Fujiwara

What are the standard treatment regimens and what investigational treatments need to be assessed ? Is it possible to perform randomised trials in these tumour types? 14:00 C1 Rare Epithelial Presenter: E.Kohn Discussant: T.Sugiyama low grade serous, mucinous, clear cell 14:30 C2 Germ Cell Presenter: R.Glasspool Discussant: R.Coleman 15:00 C3 Sex Cord Presenter: I.Ray-Coquard Discussant: N.Colombo Group D

Theme Recurrent Disease Date / Time 7th November, 2015 / 4:00 p.m. ~ 5:30 p.m. Room Jikei 3F Lecture Room Co-Chairs E.Pujade-Lauraine & D.Aoki

16:00 D1 What are the subgroups for clinical trials in Presenter:MR.Mirza recurrent ovarian cancer? Discussant: D.Lorusso i.e. multiple lines (>3), refractory, resistant, platinum-sensitive, asymptomatic CA125 rise, with or without prior antiangiogenic therapy, BRCA positive or not, etc.. 16:30 D2 What are the control arms for clinical trials Presenter: A.Oza in recurrent ovarian cancer? Discussant: A.du Bois according to the main subgroups defined in I 17:00 D3 What are the endpoints for clinical trials in Presenter: I.Vergote recurrent ovarian cancer ? Discussant: A.Reuss i.e; PFS (1&2) RECIST/CA125, OS, PROs & Symptom Benefit & Health-related QoL, cost- effectiveness, etc.. according to the main subgroups Program （Nov. 6, 2015)

Room Jikei 3F Lecture Room 9:00~ Ovarian Rare Tumors Conference -Young A.Gonzalez 13:00 Investigator Seminar

9:00 Low grade serous Keynote lecture: E.Pujade-Lauraine Discussant: J.Ledermann 10:30 Mucinous Keynote lecture: A.Gonzalez Discussant: M.Bookman 12:00 Clear cell Keynote lecture: BG.Kim Discussant: M.Quinn 15:00 Scientific Committee (Closed) 18:00 Welcome Reception and Dinner(@The Place of Tokyo TOWER ROOM) [13 min. on foot] Program （Nov. 7, 2015)

Room Jikei 3F Lecture Room 8:00 Welcome – Introductions and Background K.Ochiai 8:30 Scope, goals and Methodology G.Stuart 9:00 Questions to be addressed A.Okamoto 9:15 Obstacles to Academic Trials A.Gonzalez 9:45 Refreshment Break 10:00 GROUP A: Individualized Therapy and Patient Factors P.Harter, M.Bookman 11:30 GROUP B: First line Intervention J.Ledermann, JW Kim 13:00 Lunch (Jikei 5-6F Lecture Room) 14:00 Group C: Rare Tumours (future approaches) M.Quinn , K.Fujiwara 16:00 GROUP D: Recurrent Disease E.Pujade-Lauraine, D.Aoki 17:30 Summary and instructions for next day 18:30 Dinner (@Roppingi KINGYO) [ 20 min. by chartered bus] Program （Nov. 8, 2015)

Room Toranomon Hills 8:00 Plenary Presentation F.Joly, M.Friedlander 9:00 Plenary Discussion: Supportive Care K.Ochiai, G.Stuart 9:30 Parallel Breakout Discussion for Groups A, B, C and D. 10:30 Refreshment break 10:45 Parallel Breakout Discussion for Groups A, B, C and D. (cont.) 13:00 Lunch(Catering) 14:30 Preliminary statement presentations and audience feedback: Group A 15:15 Preliminary statement presentations and audience feedback: Group B 16:00 Refreshment break 16:30 Preliminary statement presentations and audience feedback: Group C 17:15 Preliminary statement presentations and audience feedback: Group D 19:00 Dinner (@TBD) [ in the same building] Program （Nov. 9, 2015)

Room Toranomon Hills & Jikei 3F Lecture Room 8:00 Reconvene Parallel Breakout Discussion Groups Formulation of statements 10:00 Refreshment Break 10:30 Final Presentation of Statements: Group A1, A2, A3 11:00 Group B1, B2, B3 11:30 Group C1, C2, C3 12:00 Group D1, D2, D3 12:30 Lunch Move to Jikei Univ. on foot 14:00 Final Voting on statements 15:30 Closing Remarks 17:00 Scientific Committee meeting Social Programs

DATE TIME VENUE ACCESS Info. FOODS Nov. 6th (Fri) 18:00-20:00 The Place of Tokyo 3-5-4 Shibakoen, Western Food (Buffet) Minato-ku,Tokyo,105-0011 Style : Seated Tel: 81-3-5733-6788 Free refills for 2hours http://place-tokyo.com/ (Beer, Wine, Cocktails, Softdrinks, etc.) Nov. 7th (Sat) 18:30-20:30 Roppongi KINGYO 3-14-7 Roppongi, Bento Box Minato-ku,Tokyo,106-0032 Style : Seated Tel: 81-3-3478-3000 Free refills for 2hours http://www.kingyo.co.jp/en/ (Beer, Wine, Cocktails, Softdrinks, etc.) Nov. 8th (Sun) 19:00-21:00 Green Rattan 1-23-3 Toranomon, Asian Food (Buffet) Minato-ku, Tokyo, 105-6302 Style : Seated (Tentative) TEL: 81-3-5157-5566

Green Rattan Roppongi KINGYO The Place of Tokyo 5th OCCC and Related Meetings

• Nov. 7-9, 2015 5th OCCC The Jikei University, Tokyo, Japan

• Nov. 10-11, 2015 GCIG meeting The Jikei University, Tokyo, Japan

• Nov. 12-14, 2015 The 4th Biennual Meeting of Asian Society Gynecologic Oncology (ASGO) , Seoul, Korea To ASGO SEOUL, KOREA # of direct flight from TOKYO, JAPAN Departure HND→ICN HND→GMP NRT→ICN GMP 6:00~ 2 7:00~ 8:00~ 2 9:00~ 2 2 ICN 10:00~ NRT 11:00~ 2 12:00~ 2 1 13:00~ 3 14:00~ HND 15:00~ 1 16:00~ 1 17:00~ 2 18:00~ 3 As of May 2015. The code share flights 19:00~ 1 are counted as 1 flight 20:00~ 2 2 AA EY JL KE MH NH NZ OZ UA 7C 24