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  • The Effect of Selected Herbal Extracts on Lactic Acid Bacteria Activity
    applied sciences Article The Effect of Selected Herbal Extracts on Lactic Acid Bacteria Activity Małgorzata Ziarno 1,* , Mariola Kozłowska 2 , Iwona Scibisz´ 3 , Mariusz Kowalczyk 4 , Sylwia Pawelec 4 , Anna Stochmal 4 and Bartłomiej Szleszy ´nski 5 1 Division of Milk Technology, Department of Food Technology and Assessment, Institute of Food Science, Warsaw University of Life Sciences–SGGW (WULS–SGGW), 02-787 Warsaw, Poland 2 Department of Chemistry, Institute of Food Science, Warsaw University of Life Sciences–SGGW (WULS–SGGW), 02-787 Warsaw, Poland; [email protected] 3 Division of Fruit, Vegetable and Cereal Technology, Department of Food Technology and Assessment, Institute of Food Science, Warsaw University of Life Sciences–SGGW (WULS–SGGW), 02-787 Warsaw, Poland; [email protected] 4 Department of Biochemistry and Crop Quality, Institute of Soil Science and Plant Cultivation, State Research Institute, 24-100 Puławy, Poland; [email protected] (M.K.); [email protected] (S.P.); [email protected] (A.S.) 5 Institute of Horticultural Sciences, Warsaw University of Life Sciences–SGGW (WULS–SGGW), 02-787 Warsaw, Poland; [email protected] * Correspondence: [email protected]; Tel.: +48-225-937-666 Abstract: This study aimed to investigate the effect of plant extracts (valerian Valeriana officinalis L., sage Salvia officinalis L., chamomile Matricaria chamomilla L., cistus Cistus L., linden blossom Tilia L., ribwort plantain Plantago lanceolata L., marshmallow Althaea L.) on the activity and growth of lactic acid bacteria (LAB) during the fermentation and passage of milk through a digestive system model. Citation: Ziarno, M.; Kozłowska, M.; The tested extracts were also characterized in terms of their content of polyphenolic compounds and Scibisz,´ I.; Kowalczyk, M.; Pawelec, S.; antioxidant activity.
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  • A Abdominal Aortic Aneurysm, 1405–1419 ABR. See Auditory
    Index A Acute chest syndrome, 2501 Abdominal aortic aneurysm, 1405–1419 Acute cold stress, 378 ABR. See Auditory brainstem response (ABR) Acute cytokines, 3931 Abyssinones, 4064, 4073 Acute estrogen deprivation, 1336 Accelerated atherosclerosis, 3473, 3474, Acute ischemic stroke (AIS), 2195, 2198, 3476, 3478 2209, 2246–2252, 2265 Accidental hypothermia, 376 Acute kidney injury (AKI), 2582–2584, ACEIs. See Angiotensin-converting enzyme 2587–2591 inhibitors (ACEIs) Acute respiratory distress syndrome, 635 A549 cells, 177, 178 Acyl-CoA dehydrogenase (Acyl-CoADH), 307 Acetaldehyde, 651, 653, 1814 AD. See Alzheimer’s disease (AD) Acetaminophen, 630–631, 1825 Adaptation to intermittent hypoxia (AIH), N-acetyl-p-benzoquinone imine (NAPQI), 2213–2214 1771, 1773–1775 Adaptive immunity in interstitial lung N-Acetylaspartate, 2436 disease, 1616 Acetylcholine (ACh), 2277, 2278, 2280, 2281, Adaptive response, 1796–1798 2286, 2910, 2915 Adaptor protein SchA, 915 Acetylcholine receptor (ACh-R), 2910 AD assessment scale, cognitive scale Acetylcholinesterase (AChE) inhibitors, 2356, (ADAScog), 2362 2359, 3684 Ade´liepenguins (Pygoscelis adeliae),53 N-Acetyl-L-cysteine, 3588–3590, 3592 Adenine, 900, 902, 932 Acetyl radical, 2761 Adenine nucleotide translocase (ANT), 900, Acetylsalicylic acid (ASA), 2382–2383 902–905, 917, 918, 921, 922, 928 ACh. See Acetylcholine (ACh) Adenosine, 382, 387, 1951, 1953–1954, 2915 Acid b-oxidation, 798 Adenosine deaminase, 2436, 2440 Acidosis, 380–381, 3950, 3951, 3954–3956 Adenosine diphosphate (ADP), 3383–3386 Aconitase,
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  • Marker Compounds in Java Tea Characterized by HP-TLC
    See discussions, stats, and author profiles for this publication at: https://www.researchgate.net/publication/290095979 Marker compounds in Java tea characterized by HP-TLC Technical Report · September 2015 CITATIONS READS 0 55 2 authors: Rene De Vaumas Tiên Do Extrasynthese CAMAG 8 PUBLICATIONS 39 CITATIONS 7 PUBLICATIONS 43 CITATIONS SEE PROFILE SEE PROFILE Some of the authors of this publication are also working on these related projects: CAMAG application note View project Edelweiss Phenylpropanoids View project All content following this page was uploaded by Rene De Vaumas on 12 January 2016. The user has requested enhancement of the downloaded file. Marker compounds in Java tea characterized by HPTLC René de Vaumas, EXTRASYNTHESE (*) and Tiên Do, CAMAG (**) Published in : CBS 115 (2015) 13-15 The subject of this article brings together two companies who have a common interest in sharing the importance of knowledge about excellent phytochemical reference materials, medicinal plants and their constituents, and the use of HPTLC as a standardized analytical method. EXTRASYNTHESE is an independent French company with a catalogue of hundreds of reference materials which can be used for regulatory and quality testing, analyzed predominantly with HPTLC. The activities of CAMAG’s laboratory in the analysis of phytochemicals are well documented in its dedication to the world-wide recognition and acceptance of HPTLC as the standard method for plant analysis. In this article the focus is on specific markers in method development for the analysis of complex plant extracts. Introduction Orthosiphon is an Indonesian medicinal plant which is widely used as an herbal tea commonly known as Java tea.
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  • M.Sc. CHEMISTRY
    M.Sc. CHEMISTRY ANALYTICAL CHEMISTRY SPECIALISATION SYLLABUS OF III & IV SEMESTERS REVISED AS PER NEW (CB) SYLLABUS FOR STUDENTS ADMITTED FROM THE YEAR 2016 ONWARDS M.Sc. CHEMISTRY (ANALYTICAL CHEMISTRY SPECIALISATION) Syllabus for III and IV Semesters (for the batches admitted in academic year 2016 & later under CBCS pattern) [Under Restructured CBCS Scheme] Grand total marks and credits (all 4 semesters) 2400 marks – 96 credits (Approved in the P.G. BOS meeting held on 01-07-2017) Semester - III (ANALYTICAL CHEMISTRY) [Under CBCS Scheme] (for the batches admitted in academic year 2016 & later under CBCS pattern) Hrs/week Internal assessment Semester exam Total Credits CH(AC)301T (core) 4 20 marks 80 marks 100 marks 4 CH(AC)302T (core) 4 20 marks 80 marks 100 marks 4 CH(AC)303T (Elective) 4 20 marks 80 marks 100 marks 4 CH(AC)304T (Elective) 4 20 marks 80 marks 100 marks 4 CH(AC)351P (LAB-I) 9 100 marks 4 CH(AC)352P (LAB-II) 9 100 marks 4 Total 600 marks 24 Semester - IV (ANALYTICAL CHEMISTRY) Hrs/week Internal assessment Semester exam Total Credits CH(AC)401T (core) 4 20 marks 80 marks 100 marks 4 CH(AC)402T (core) 4 20 marks 80 marks 100 marks 4 CH(AC)403T (Elective) 4 20 marks 80 marks 100 marks 4 CH(AC)404T (Elective) 4 20 marks 80 marks 100 marks 4 CH(AC)451P (LAB-I) 9 100 marks 4 CH(AC)452P (LAB-II) 9 100 marks 4 Total 600 marks 24 Grand total marks and credits (all 4 semesters) 2400 marks - 96 credits M.Sc.ANALYTICAL CHEMISTRY Semester III Paper I :CH (AC) 301T: CORE : Sampling, Data handling, Classical and Atomic spectral methods
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  • Phytoalexins: Current Progress and Future Prospects
    Phytoalexins: Current Progress and Future Prospects Edited by Philippe Jeandet Printed Edition of the Special Issue Published in Molecules www.mdpi.com/journal/molecules Philippe Jeandet (Ed.) Phytoalexins: Current Progress and Future Prospects This book is a reprint of the special issue that appeared in the online open access journal Molecules (ISSN 1420-3049) in 2014 (available at: http://www.mdpi.com/journal/molecules/special_issues/phytoalexins-progress). Guest Editor Philippe Jeandet Laboratory of Stress, Defenses and Plant Reproduction U.R.V.V.C., UPRES EA 4707, Faculty of Sciences, University of Reims, PO Box. 1039, 51687 Reims cedex 02, France Editorial Office MDPI AG Klybeckstrasse 64 Basel, Switzerland Publisher Shu-Kun Lin Managing Editor Ran Dang 1. Edition 2015 MDPI • Basel • Beijing ISBN 978-3-03842-059-0 © 2015 by the authors; licensee MDPI, Basel, Switzerland. All articles in this volume are Open Access distributed under the Creative Commons Attribution 3.0 license (http://creativecommons.org/licenses/by/3.0/), which allows users to download, copy and build upon published articles even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. However, the dissemination and distribution of copies of this book as a whole is restricted to MDPI, Basel, Switzerland. III Table of Contents About the Editor ............................................................................................................... VII List of
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  • Biologically Active Substances from Unused Plant Materials
    Biologically active substances from unused plant materials Petra Lovecká1, Anna Macůrková1, Kateřina Demnerová1, Zdeněk Wimmer2 1Department of Biochemistry and Microbiology, 2Departement of Chemistry of Natural Compounds, University of Chemistry and Technology Prague Technická 3, 166 28 Prague 6, Czech Republic Keywords: Magnolia, honokiol, obovatol, biological activities. Presenting author email: [email protected] Natural products, such as plants extract, either as pure compounds or as standardized extracts, provide unlimited opportunities for new drug discoveries because of the unmatched availability of chemical diversity. Probably based on historical background we utilize only certain plant parts. In many cases there is not enough of required material or collection damages plant itself. The possible solution we could find in utilization of unused or waste plant parts. This work is focused on analysis of bioactive compounds content in different parts of medicinal plants such as genus Magnolia. Stem bark of these trees are part of Chinese traditional medicine. The collection of stem bark is devastating for the tree. Flowers and leaves from Magnolia tripetala, Magnolia obovata and their hybrids were separately extracted with 80% methanol. Resulting methanolic extract were subsequently fractionated with chloroform under acidic conditions and mixture of chloroform and methanol under basic conditions in term of increasing polarity (Harborne, 1998) into four fractions, neutral, moderately polar, basic and polar extract. Each extract was screened
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  • ABSTRACT Title of Document: BIOLOGICAL
    ABSTRACT Title of Document: BIOLOGICAL EFFICACY, MECHANISMS OF ACTIONS OF SOY-DERIVED PHYTOALEXIN GLYCEOLLINS IN PREVENTION OF CHRONIC DISEASES Haiqiu Huang, Doctor of Philosophy, 2014 Directed By: Professor Liangli (Lucy) Yu Department of Nutrition and Food Science Cardiovascular disease (CVD) is the leading cause of deaths worldwide. Prostate cancer is the most prevalent cancer in U.S. male population. Diet-induced hypercholesterolemia and chronic inflammation promote the development of both CVD and prostate cancer. Glyceollins are a group of soy phytoalexins possessing a variety of biological activities. This research project focused on characterizing glyceollins’ bioactivities in alleviating cholesterol dysregulation, prevention of prostate cancer, and regulating gut microbiome. The first part of the project aimed to evaluate glyceollins’ cholesterol- lowering effect in-vivo. Male golden Syrian hamsters were fed high-fat diet with or without glyceollins supplementation for 28 days. Glyceollins supplementation led to a significant reduction of plasma VLDL, hepatic cholesterol esters and total lipid content. Consistent with changes in circulating cholesterol, glyceollins supplementation also altered expression of the genes related to cholesterol metabolism in the liver. The second part of the study aimed to evaluate glyceollins’ effect in reducing prostate cancer tumor growth in a xenograft model. An initial delayed appearance of tumor was observed in a PC-3 xenograft model. However, no difference in tumor sizes was observed in a LNCaP xenograft model. Extrapolation analysis of tumor measurements indicated that no difference in sizes was expected for both PC-3 and LNCaP tumors. Glyceollins had no effect on the androgen responsive pathway, its proliferation, cell cycle, or on angiogenesis genes in tumor and xenobiotic metabolism, cholesterol transport, and inflammatory cytokine genes in liver.
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  • Sideritis Clandestina (Bory & Chaub.) Hayek; Sideritis Raeseri Boiss
    2 February 2016 EMA/HMPC/39455/2015 Committee on Herbal Medicinal Products (HMPC) Assessment report on Sideritis scardica Griseb.; Sideritis clandestina (Bory & Chaub.) Hayek; Sideritis raeseri Boiss. & Heldr.; Sideritis syriaca L., herba Final Based on Article 16d(1), Article 16f and Article 16h of Directive 2001/83/EC as amended (traditional use) Herbal substances (binomial scientific name of Sideritis scardica Griseb.; Sideritis clandestina the plant, including plant part) (Bory & Chaub.) Hayek; Sideritis raeseri Boiss. & Heldr.; Sideritis syriaca L., herba Herbal preparation Comminuted herbal substance Pharmaceutical form Comminuted herbal substance as herbal tea for oral use Rapporteur I. Chinou Peer-reviewer B. Kroes 30 Churchill Place ● Canary Wharf ● London E14 5EU ● United Kingdom Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5555 Send a question via our website www.ema.europa.eu/contact An agency of the European Union © European Medicines Agency, 2016. Reproduction is authorised provided the source is acknowledged. Table of contents Table of contents ................................................................................................................... 2 1. Introduction ....................................................................................................................... 4 1.1. Description of the herbal substance(s), herbal preparation(s) or combinations thereof .. 4 1.2. Search and assessment methodology ..................................................................... 8 2. Data on
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  • Treatment Repurposing for Inflammatory Bowel Disease Using Literature-Related Discovery and Innovation Kostoff RN, Briggs MB, Shores DR
    ISSN 1007-9327 (print) ISSN 2219-2840 (online) World Journal of Gastroenterology World J Gastroenterol 2020 September 7; 26(33): 4889-5059 Published by Baishideng Publishing Group Inc World Journal of W J G Gastroenterology Contents Weekly Volume 26 Number 33 September 7, 2020 FRONTIER 4889 Treatment repurposing for inflammatory bowel disease using literature-related discovery and innovation Kostoff RN, Briggs MB, Shores DR REVIEW 4900 Tumor microenvironment in primary liver tumors: A challenging role of natural killer cells Polidoro MA, Mikulak J, Cazzetta V, Lleo A, Mavilio D, Torzilli G, Donadon M MINIREVIEWS 4919 Exploring the food-gut axis in immunotherapy response of cancer patients Russo E, Nannini G, Dinu M, Pagliai G, Sofi F, Amedei A ORIGINAL ARTICLE Basic Study 4933 Tumor necrosis factor alpha receptor 1 deficiency in hepatocytes does not protect from non-alcoholic steatohepatitis, but attenuates insulin resistance in mice Bluemel S, Wang Y, Lee S, Schnabl B 4945 Resveratrol alleviates intestinal mucosal barrier dysfunction in dextran sulfate sodium-induced colitis mice by enhancing autophagy Pan HH, Zhou XX, Ma YY, Pan WS, Zhao F, Yu MS, Liu JQ Retrospective Study 4960 Effects of denosumab treatment in chronic liver disease patients with osteoporosis Saeki C, Saito M, Oikawa T, Nakano M, Torisu Y, Saruta M, Tsubota A 4972 Bowel function and quality of life after minimally invasive colectomy with D3 lymphadenectomy for right- sided colon adenocarcinoma Lee KM, Baek SJ, Kwak JM, Kim J, Kim SH 4983 Acute liver failure and death
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  • Chapter Two Biomimetic Partial Synthesis Of
    CHAPTER TWO BIOMIMETIC PARTIAL SYNTHESIS OF VALPARICINE AND APPARICINE 2.1 Introduction 2.1.1 Alkaloids of Kopsia arborea A total of 62 alkaloids were isolated from the stem-bark and leaves of Kopsia arborea of which 25 are new alkaloids. Among the alkaloids isolated are valparicine (28),26,27 pericine (31),26,28,29 pericidine (32),30,31 arbophylline (33),32 arboricine (34),30,33 arboricinine (35),30,33 arboflorine (36),30,34 arboloscine (37),30,31 and mersicarpine (38).35 14 The compounds of interest to this research are valparicine (28) and pericine (31). Valparicine (28) was isolated from the stem-bark extract of K. arborea in trace amount. It represents the first member of the pericine-type alkaloids, characterized by a 16-22 exocyclic double bond, in which bond-formation has occurred between C-3 and C-7.26 Preliminary tests indicated that valparicine (28) showed strong cytotoxic effects −1 against human KB cells (IC50 < 5 μgmL ). Valparicine (28) was obtained as a colorless oil, with [α]D −40 (c 0.22, CHCl3). The UV spectrum (228 and 297 nm) indicated the presence of an unsubstituted indolenine chromophore. The EIMS of 28 showed a molecular ion at m/z 276, which 13 analyzed for C19H20N2, differing from pericine (31) by loss of two hydrogens. The C NMR spectrum gave a total of 19 carbon resonances (one methyl, five methylenes, seven methines, and six quaternary carbons) in agreement with the molecular formula. In addition to the six carbon resonances readily attributable to the aromatic moiety, and the imine resonance at δC 186.4, two other downfield quaternary resonances were observed at δC 139.2 and 144.6.
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  • (12) Patent Application Publication (10) Pub. No.: US 2006/0165636A1 Hasebe Et Al
    US 2006O165636A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2006/0165636A1 HaSebe et al. (43) Pub. Date: Jul. 27, 2006 (54) HAIR TREATMENT COMPOSITION AND (52) U.S. Cl. .......................................................... 424/70.14 HAIR COSMETC FOR DAMAGED HAIR (76) Inventors: Kouhei Hasebe, Gifu (JP); Kikumi (57) ABSTRACT Yamada, Gifu (JP) Correspondence Address: The present invention intends to provide a composition for FRISHAUF, HOLTZ, GOODMAN & CHICK, PC hair treatment containing Y-polyglutamic acid or a salt 220 Fifth Avenue thereof, a hair cosmetic for damaged hair containing Such a 16TH Floor composition, and their uses. The composition for hair treat NEW YORK, NY 10001-7708 (US) ment containing Y-polyglutamic acid or a salt thereof and the hair cosmetic for damaged hair of the present invention have (21) Appl. No.: 10/547,492 excellent improvement effects on the strength and frictional (22) PCT Filed: Mar. 3, 2004 force of hair, so that they can provide tension, elasticity, or the like to damage hair to prevent or alleviate split hair and (86). PCT No.: PCT/PO4/O2606 broken hair as well as improvements in combing and touch. (30) Foreign Application Priority Data Furthermore, they also exert effects of moisture retention inherent to Y-polyglutamic acid or a salt thereof, preventing Mar. 10, 2003 (JP)......................................... 2003-62688 or improving effects on the generation of dandruff on the basis of such effects, preventing effects on the feeling of Publication Classification Stickiness or creak, and various effectiveness including (51) Int. Cl. appropriate residual tendency to hair in a simultaneous A6 IK 8/64 (2006.01) manner, respectively.
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  • Incorporation of Elastase Inhibitor in Silk Fibroin Nanoparticles for Transdermal Delivery
    Universidade do Minho Escola de Engenharia Ana Vanessa Fernandes Ferreira Incorporation of Elastase Inhibitor in Silk Fibroin Nanoparticles for Transdermal Delivery Incorporation of Elastase Inhibitor in Silk Fibroin DeliveryNanoparticles for Transdermal Ana Vanessa Fernandes Ferreira Fernandes Ana Vanessa Uminho | 2013 Uminho Outubro de 2013 Universidade do Minho Escola de Engenharia Ana Vanessa Fernandes Ferreira Incorporation of Elastase Inhibitor in Silk Fibroin Nanoparticles for Transdermal Delivery Dissertação de Mestrado Mestrado em Bioengenharia Trabalho efetuado sob a orientação do Professor Doutor Artur Cavaco Paulo e coorientação de Doutora Ana Sofia Lemos Machado Abreu Outubro de 2013 DECLARAÇÃO Nome: Ana Vanessa Fernandes Ferreira Endereço eletrónico: [email protected] Título da dissertação: Incorporação de Inibidor de Elastase em Nanopartículas de Fibroína de Seda para Aplicações Transdérmicas (Incorporation of Elastase Inhibitor in Silk Fibroin Nanoparticles for Transdermal Delivery) Orientador (es): Professor Artur Cavaco Paulo e Ana Sofia Lemos Machado Abreu Ano de conclusão: 2013 Designação do Mestrado: Mestrado em Bioengenharia É AUTORIZADA A REPRODUÇÃO INTEGRAL DESTA TESE/TRABALHO APENAS PARA EFEITOS DE INVESTIGAÇÃO, MEDIANTE DECLARAÇÃO ESCRITA DO INTERESSADO, QUE A TAL SE COMPROMETE. Universidade do Minho, 29/11/2013 Assinatura: ____________________________________________________________________________ No amount of experimentation can ever prove me right; a single experiment can prove me wrong. - Albert Einstein To my beloved family Este trabalho não teria sido possível sem a colaboração das pessoas que me ajudaram a concretizá-lo,Agradecimentos tanto a nível profissional / Acknoledgments como pessoal. Agradeço ao meu orientador, Professor Dr. Artur Cavaco Paulo, pela oportunidade de ingressar no seu grupo de trabalho e neste projeto de investigação, por ter confiado e acreditado nas minhas capacidades e potencial, pelo seu apoio e incentivo nestes últimos dois anos.
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