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European Society of Mycobacteriology ESM European Society of Mycobacteriology In co-organization with the Instituto Nacional de Saúde Dr. Ricardo Jorge CONTENTS • Welcome Message • Introduction to the European Society of Mycobacteriology • Congress Organization • Program at a glance • Programme of Guest Lectures, Oral Presentations and Symposia • Programme of Poster Presentations • Abstracts of Guest Lectures (GL) • Abstracts of Oral Presentations (OP) • Abstracts of Poster Presentations (PP) • Author Index European Society of Mycobacteriology | 30th Annual Congress | July 2009 | Porto - Portugal 1 WELcoME MESSAGE Dear Colleagues, It is with great pleasure that we warmly welcome you to the 30th Annual Congress of the European Society of Mycobacteriology, held in the city of Porto in Portugal from July 5-8, 2009. The aim of ESM2009 is to promote the exchange of distinguished experts from all around the world who will have the opportunity to update information in the front-line of scientific achievement, share experience and ideas, and actively participate in contribution to the field of mycobacteriology. We have worked hard to make your stay in Porto a pleasant, useful and memorable occasion. On behalf of the ESM and the Local Organisers, Suzana David 2 ESM 2009 EUROPEAN SOCIETY OF MYcoBACTERIOLOGY 30TH ANNUAL ConGRESS JULY 5-8, 2009 PORto, PORTUGAL The European Society of Mycobacteriology (ESM, http://www.esmycobacteriology.eu), founded in 1980, is a non-profit international scientific society dealing with different aspects of mycobacteriology and related diseases. It is considered one of the most active international scientific societies in this area, being committed to: - Encouraging the highest standards for research to facilitate the discovery of new knowledge; - Coordinating and providing information and expertise to other organizations worldwide; - Disseminating knowledge on all aspects of mycobacteriology and related diseases, through scientific meetings and publications, - Encouraging and providing the highest standards of training to interested health care providers; - Establishing, reviewing and revising guidelines; - Promoting high quality and cost effective diagnostic procedures; - Advising, cooperating and participating with government and non-government agencies in matters of common interest; - Participating in activities whose aim is to prevent mycobacterial diseases worldwide. The ESM meetings are held each year in a different country of Europe. The ESM2009 congress is hosted in the city of Porto, in Portugal. International specialists will treat themes at the front-line of scientific achievement in the field of mycobacteriology and related diseases. As in previous meetings, the scientific program of the conferences covers a wide range of topics in both applied and fundamental research in areas of priority such as: - Diagnostics of active and latent tuberculosis - Diagnostics of atypical mycobacteria - Molecular epidemiology of tuberculosis - Antibiotic resistance, MDR, XDR - Tuberculosis drug development - Immunology of mycobacterial infections - Molecular Biology of mycobacteria - Taxonomy of the genus Mycobacterium - Veterinarian and environmental Mycobacteriology - Methods for diagnostics adapted to economically disfavoured settings - Laboratory safety - Short and long term programs and recommendations European Society of Mycobacteriology | 30th Annual Congress | July 2009 | Porto - Portugal 3 ConGRESS ORGANIZATIon EUROPEAN SOCIETY OF MYCOBACTERIOLOGY http://www.esmycobacteriology.eu Chairman of the ESM 2009 congress Suzana David (Lisbon, Portugal) Steering Committee General Secretary Enrico Tortoli (Firenze, Italy) President Todor Kantardjiev (Sofia, Bulgaria) Treasurer Malcolm Yates (East Dulwich Grove, U.K.) Members Maria-Jesus Garcia (Madrid, Spain) Sven Hoffner (Solna, Sweden) Stefan Niemann (Borstel, Germany) Gabriela Pfyffer (Luzern, Switzerland) Nalin Rastogi (Guadeloupe, France) Veronique Vincent (Geneva, Switzerland) HONORS COMMITTEE ESM 2009 Ana Jorge Minister of Health Mariano Gago Minister of Science, Technology and Higher Education Manuel Pizarro Secretary of State for Health Francisco Ramos Secretary of State for Health José Pereira Miguel President of the National Health Institute Dr. Ricardo Jorge Jorge Sampaio UN Secretary General’s Special Envoy to Stop TB Mario Raviglione Director of the Stop TB Department, World Health Organization Maria do Céu Machado High Comissioner for Health Francisco George Director-General of Health Jorge Soares Director of the Health and Human de- velopment Service Calouste Gulbenkian Foundation Jorge Torgal Director do Institute of Hygiene and Tropical Medicine Rui Rio Mayor of the city of Porto Fernando Augusto Fiuza de Melo Director of the Clemente Ferreira Institute, São Paulo, Brasil 4 ESM 2009 COORGANIZERS European Society of Mycobacteriology http://www.esmycobacteriology.eu Instituto Nacional de Saúde Dr. Ricardo Jorge, INSA http://www.insa.pt PARTNERS Foundation for Science and Technology (FCT) http://www.fct.mctes.pt Fundação Calouste Gulbenkian http://www.gulbenkian.pt Luso-American Foundation (FLAD) http://www.flad.pt STOP-TB Working Group on New Diagnostics, Point of Care sub group http://www.stoptb.org SPONSORS The Organization expresses its thanks and appreciation to all those who gener- ously contributed to the success of the 30th Annual Congress of ESM. HAIN LifeSciences http://www.hain-lifescience.com Platinum Medal Sponsor Beckton Dickinson & Quilaban http://www.bd.com http://www.quilaban.pt Gold Medal Sponsor BioMerieux http://www.biomerieux.com Gold Medal Sponsor Microsens (logo) http://www.microsens.com Cepheid http://www.cepheid.com Genoscreen http://www.genoscreen.com European Society of Mycobacteriology | 30th Annual Congress | July 2009 | Porto - Portugal 5 PROGRAM AT A GLANCE Sunday, July 5th 09h00 REGISTRATION 11h00 – 12h00 SYMPOSIUM SPONSORED BY HAIN LIFESCIENCE GMBH: RAPID MOLECULAR GENETIC DETECTION OF MDR- AND XDR-TB Chair: Michael Weizenegger Speakers: Doris Hillemann and Christopher M Gilpin 12h00 – 13h30 SYMPOSIUM SPONSORED BY STOP-TB WORKING GROUP ON NEW DIAGNOSTICS, POINT OF CARE SUB GROUP: A SYMPOSIUM ON POINT-OF-CARE TESTS FOR TUBERCULOSIS Speakers: Catharina Boehme, Carol Nawina Nyirenda, Rosanna Peeling, Gerd Michel, Ruth McNerney and Amy P Wong 13h30 – 15h30 Break for Lunch 15h30 – 16h30 SYMPOSIUM CO-SPONSORED BY BECTON, DICKINSON AND COMPANY AND QUILABAN - QUÍMICA LABORATORIAL ANALÍTICA LDA: SUCCEPTIBILITYTESTING AND TREATMENT OF TB IN THE ERA OF MDR-TB AND XDR-TB. DO WE USE THE RIGHT DRUGS AND TOOLS? Chair: Francoise Portaels and Salman Siddiqi Speakers: Stefan Winkler, Andre De Bock, and Virginia Crews 17h00 – 19h00 OPENING SESSION Welcome Address TB CONTROL PROGRAMS Chair: Jaime Nina and Cristina Furtado Guest Lecture-1: Miguel Villar Guest Lecture-2: Fernando Fiuza de Melo 19h15 Welcome Reception Monday, July 6th 09h00 – 13h15 SCIENTIFIC SESSION ON MOLECULAR EPIDEMIOLOGY AND DRUG RESISTANCE SURVEILLANCE Chair: Stefan Niemann and Cristina Gutierez 9h00 – 9h45 Guest Lecture-3: Sebastien Gagneux 9h45 – 11h00 Oral Presentations 11h00 – 11h30 Coffee and tea Chair: Nalin Rastogi and Dr. Philip Supply 11h30 – 12h15 Guest Lecture-4: Dick van Soolingen 12h15 – 13h015 Oral Presentations 13h15 – 14h00 Lunch 6 ESM 2009 14h00 – 15h00 POSTER SESSION 15h00 – 16h45 SCIENTIFIC SESSION ON NON TUBERCULOUS MYCOBACTERIA Chair: Enrico Tortoli 15h00 – 15h45 Guest Lecture-5: Joseph O. Falkinham, III 15h45 – 16h45 Oral Presentations 16h45 – 17h15 Coffee and tea 17h15 – 19h15 SCIENTIFIC SESSION ON ISSUES IN THE MODERN TB LABORATORY Chair: Gabriela Pfyffer and Thomas Shinnick 17h15 – 18h00 Guest Lecture-6 : Dr. Jean-Pierre Zellweger 18h00 – 18h30 Guest Lecture-7 : Lee W. Riley 18h30 – 19h15 Oral Presentations 19h30 Visit and Dinner at the Port Wine Cellars Tuesday, July 7th 09h00 – 12h30 SCIENTIFIC SESSION ON VACCIN DEVELOPMENT AND PATHOGENESIS Chair: David Minnikin 09h00 – 09h45 Guest Lecture-8: Carlos Martin 09h45 – 10h30 Guest Lecture-9 : Lee W. Riley 10h30 – 11h00 Coffee and tea 11h00 – 12h30 Oral Presentations 12h30 – 13h15 Lunch 13h15 – 14h15 BUSINESS MEETING 14h15 – 18h15 SCIENTIFIC SESSION ON LABORATORY STRENGTHENING Chair: Dr. Sven Hoffner and Dr. Mark Perkins 14h15 – 15h00 Guest Lecture-10: Thomas Shinnick 15h00 – 15h45 Guest Lecture-11: Afrânio Kritski 15h45 – 16h30 Guest Lecture-12 : Moisés Palaci 16h30 – 17h00 Coffee and tea 17h00 – 17h45 Oral Presentations 17h45 – 18h15 BEST POSTER 18h30 Cultural Evening Dinner European Society of Mycobacteriology | 30th Annual Congress | July 2009 | Porto - Portugal 7 Wednes- 09h00 – 11h00 SCIENTIFIC SESSION ON DRUG DEVELOPMENT day, July 8th Chair: Dr. Nalin Rastogi 09h00-09h45 Guest Lecture-13: Clarice Queico Leite 09h45 – 10h30 Guest Lecture-14 : Moisés Palaci 10h30 – 11h00 Oral Presentations 11h00 – 11h30 Coffee and tea 11h30 – 12h20 SESSION ON PRACTICAL ASPECTS AND QUALITY ASSURANCE IN MOLECULAR EPIDEMIOLOGY Chair: Dr. Elvira Richter and Prof. Christophe Sola 11h30 – 12h00 Guest Lecture-15 : Philip Supply 12h00 – 12h20 Oral Presentation 12h20 – 12h30 Discussion 12h30 – 13h30 SYMPOSIUM SPONSORED BY INSTAND, SOCIETY FOR RESEARCH PROMOTION OF QUALITY ASSURANCE IN MEDICAL LABORATORIES, WHO COLLABORATING CENTRE, DUESSELDORF, GERMANY: EXTERNAL QUALITY ASSURANCE Speakers: Elvira Richter, Girts Skenders, Akos SomoskÖvy 13h:30 – 13h45 Closing Remarks 13h45 – 14h15 CLOSING OF CONGRESS 14h15 Conference Closes 8 ESM 2009 PROGRAMME OF GUEST LECTURES, ORAL PRESENTATIons AND SYMPOSIA Sunday, July 5th 9h00 – 11h00 REGISTRATION 11h00
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